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LearnNBP2-34720PE
antibody from Novus Biologicals
Targeting: TYRP1
b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- NBP2-34720PE - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal TYRP1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C in the dark.
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Supportive validation
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TYRP1 Antibody (TA99) [PE] [NBP2-34720PE] - An intracellular stain was performed on SK-MEL-28 cells with TYRP1 Antibody (TA99) NBP2-34720PE (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeabilized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to phycoerythrin.
