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LearnNBP2-47780AF700
antibody from Novus Biologicals
Targeting: PMEL
D12S53E, gp100, Pmel17, SI, SIL, SILV
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Product number
- NBP2-47780AF700 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal PMEL17/SILV Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa).
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Near infrared dye
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C in the dark.
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