346001

antibody from BioLegend
Targeting: SIGLEC1 CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN
Provider product page for 346001
Flow cytometry

Antibody data

Product number
346001 - Provider product page
Provider
BioLegend
Product name
Purified anti-human CD169 (Sialoadhesin, Siglec-1)
Antibody type
Monoclonal
Antigen
Human Rhinovirus (HRV14) infected, monocyte derived-DCs
Description
CD169, also known as Siglec-1 and Sialoadhesin (Sn), is a 210 kD type I single membrane-spanning glycoprotein. It is the largest member of the Siglec family, consisting of 1709 amino acids and belonging to the immunoglobulin superfamily. CD169 is expressed by macrophages and dendritic cells. By its affinity to α2,3-linked sialic acid, it is involved in macrophage binding to different cell types such as granulocytes, monocytes, NK, B and T cells. Several CD169 counter receptors, such as CD227 on human breast cancer cells, CD43 on T cells and CD206 on macrophages, have been reported.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4 °C.
SIGLEC1 protein structure - 346001 shown in red.