Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 55274-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55274-1-AP, RRID:AB_11182278
- Product name
- P62/SQSTM1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated P62/SQSTM1 antibody (Cat. #55274-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A new way for punicalagin to alleviate insulin resistance: regulating gut microbiota and autophagy.
Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways.
ROS-Triggered Autophagy Is Involved in PFOS-Induced Apoptosis of Human Embryo Liver L-02 Cells.
Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson's Disease.
An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles.
25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.
Tongxinluo Ameliorates Myocardial Ischemia-Reperfusion Injury Mainly via Activating Parkin-Mediated Mitophagy and Downregulating Ubiquitin-Proteasome System.
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Resveratrol promotes osteoblastic differentiation in a rat model of postmenopausal osteoporosis by regulating autophagy.
Morroniside Inhibits H2O2-Induced Podocyte Apoptosis by Down-Regulating NOX4 Expression Controlled by Autophagy In Vitro.
Differential Membrane Binding and Seeding of Distinct α-Synuclein Fibrillar Polymorphs.
Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism.
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
Hypusination Orchestrates the Antimicrobial Response of Macrophages.
GABARAPL2 Is Critical for Growth Restriction of Toxoplasma gondii in HeLa Cells Treated with Gamma Interferon.
AAV-Mig-6 Increase the Efficacy of TAE in VX2 Rabbit Model, Is Associated With JNK Mediated Autophagy.
Punicalagin Prevents Inflammation in LPS-Induced RAW264.7 Macrophages by Inhibiting FoxO3a/Autophagy Signaling Pathway.
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Cao Y, Ren G, Zhang Y, Qin H, An X, Long Y, Chen J, Yang L
Food & nutrition research 2021;65
Food & nutrition research 2021;65
Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways.
Ji J, Yu Q, Dai W, Wu L, Feng J, Zheng Y, Li Y, Guo C
PPAR research 2021;2021:6651839
PPAR research 2021;2021:6651839
ROS-Triggered Autophagy Is Involved in PFOS-Induced Apoptosis of Human Embryo Liver L-02 Cells.
Zeng HC, Zhu BQ, Wang YQ, He QZ
BioMed research international 2021;2021:6625952
BioMed research international 2021;2021:6625952
Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson's Disease.
Veys L, Devroye J, Lefevere E, Cools L, Vandenabeele M, De Groef L
Frontiers in neuroscience 2021;15:726476
Frontiers in neuroscience 2021;15:726476
An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles.
Ruan C, Wang C, Gong X, Zhang Y, Deng W, Zhou J, Huang D, Wang Z, Zhang Q, Guo A, Lu J, Gao J, Peng D, Xue Y
Autophagy 2021 Jun;17(6):1426-1447
Autophagy 2021 Jun;17(6):1426-1447
25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.
Cao Q, Luo J, Xiong Y, Liu Z, Ye Q
International immunopharmacology 2021 Jul;96:107643
International immunopharmacology 2021 Jul;96:107643
Tongxinluo Ameliorates Myocardial Ischemia-Reperfusion Injury Mainly via Activating Parkin-Mediated Mitophagy and Downregulating Ubiquitin-Proteasome System.
Yang HX, Wang P, Wang NN, Li SD, Yang MH
Chinese journal of integrative medicine 2021 Jul;27(7):542-550
Chinese journal of integrative medicine 2021 Jul;27(7):542-550
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
Liu YS, Yang Q, Li S, Luo L, Liu HY, Li XY, Gao ZN
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Liao Y, Hua Y, Li Y, Zhang C, Yu W, Guo P, Zou K, Li W, Sun Y, Wang R, Zuo Y, Sui S, Tian C, Hao J, Chen M, Hu S, Chen M, Long Q, Wang X, Zou L, Xie F, Guo W, Deng W
Cell death and differentiation 2021 Apr;28(4):1347-1363
Cell death and differentiation 2021 Apr;28(4):1347-1363
Resveratrol promotes osteoblastic differentiation in a rat model of postmenopausal osteoporosis by regulating autophagy.
Wang W, Zhang LM, Guo C, Han JF
Nutrition & metabolism 2020;17:29
Nutrition & metabolism 2020;17:29
Morroniside Inhibits H2O2-Induced Podocyte Apoptosis by Down-Regulating NOX4 Expression Controlled by Autophagy In Vitro.
Gao X, Liu Y, Wang L, Sai N, Liu Y, Ni J
Frontiers in pharmacology 2020;11:533809
Frontiers in pharmacology 2020;11:533809
Differential Membrane Binding and Seeding of Distinct α-Synuclein Fibrillar Polymorphs.
Shrivastava AN, Bousset L, Renner M, Redeker V, Savistchenko J, Triller A, Melki R
Biophysical journal 2020 Mar 24;118(6):1301-1320
Biophysical journal 2020 Mar 24;118(6):1301-1320
Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism.
Singla S, Iwamoto-Stohl LK, Zhu M, Zernicka-Goetz M
Nature communications 2020 Jun 11;11(1):2958
Nature communications 2020 Jun 11;11(1):2958
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
Ji J, Wu L, Feng J, Mo W, Wu J, Yu Q, Li S, Zhang J, Dai W, Xu X, Mao Y, Xu S, Chen K, Li J, Guo C
International immunopharmacology 2020 Jul;84:106529
International immunopharmacology 2020 Jul;84:106529
Hypusination Orchestrates the Antimicrobial Response of Macrophages.
Gobert AP, Finley JL, Latour YL, Asim M, Smith TM, Verriere TG, Barry DP, Allaman MM, Delagado AG, Rose KL, Calcutt MW, Schey KL, Sierra JC, Piazuelo MB, Mirmira RG, Wilson KT
Cell reports 2020 Dec 15;33(11):108510
Cell reports 2020 Dec 15;33(11):108510
GABARAPL2 Is Critical for Growth Restriction of Toxoplasma gondii in HeLa Cells Treated with Gamma Interferon.
Zhang Z, Gu H, Li Q, Zheng J, Cao S, Weng C, Jia H
Infection and immunity 2020 Apr 20;88(5)
Infection and immunity 2020 Apr 20;88(5)
AAV-Mig-6 Increase the Efficacy of TAE in VX2 Rabbit Model, Is Associated With JNK Mediated Autophagy.
Li Z, Tian Y, Qu L, Mao J, Zhong H
Journal of Cancer 2019;10(4):1060-1069
Journal of Cancer 2019;10(4):1060-1069
Punicalagin Prevents Inflammation in LPS-Induced RAW264.7 Macrophages by Inhibiting FoxO3a/Autophagy Signaling Pathway.
Cao Y, Chen J, Ren G, Zhang Y, Tan X, Yang L
Nutrients 2019 Nov 15;11(11)
Nutrients 2019 Nov 15;11(11)
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Feng J, Niu P, Chen K, Wu L, Liu T, Xu S, Li J, Li S, Wang W, Lu X, Yu Q, Liu N, Xu L, Wang F, Dai W, Xia Y, Fan X, Guo C
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 55274-1-AP(SQSTM1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 55274-1-AP(SQSTM1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The P62/SQSTM1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human P62/SQSTM1. This antibody recognizes human,mouse,rat antigen. The P62/SQSTM1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.