Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 337008 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#337008, RRID:AB_2162063
- Product name
- Alexa Fluor® 647 anti-Human Podoplanin [NC-08]
- Antibody type
- Monoclonal
- Antigen
- Podoplanin
- Description
- Podoplanin is a 40-43 kD type-I transmembrane sialomucin-type glycoprotein, also known as T1a, gp36, gp38, gp40, or Aggrus. Originally detected on the surface of podocytes, futher characterization showed podoplanin has a broad tissue distribution including many mesothelial cells, epithelial cells, follicular dendritic cells and a variety of tumor cells. It has been reported that podoplanin is the ligand of CLEC-2 and is involved in lymphatic vessel formation, platelet aggregation, and tumor metastasis. Podoplanin may serve as a useful marker for tumor diagnosis and prognosis.
- Reactivity
- Human
- Host
- Rat
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references A novel method for isolating individual cellular components from the adult human distal lung.
Fujino N, Kubo H, Ota C, Suzuki T, Suzuki S, Yamada M, Takahashi T, He M, Suzuki T, Kondo T, Yamaya M
American journal of respiratory cell and molecular biology 2012 Apr;46(4):422-30
American journal of respiratory cell and molecular biology 2012 Apr;46(4):422-30
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human glioblastoma cell line LN319 stained with NC-08 Alexa Fluor® 647
- Conjugate
- Red dye