Antibody data
- Antibody Data
- Antigen structure
- References [98]
- Comments [0]
- Validations
- Other assay [4]
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- Product number
- MA1-80091 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD11b Monoclonal Antibody (M1/70.15)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- This clone has been reported to block iC3b binding to its receptor.
- Antibody clone number
- M1/70.15
- Concentration
- 1 mg/mL
Submitted references A microengineered Brain-Chip to model neuroinflammation in humans.
Sourcing of human peripheral blood-derived myeloid angiogenic cells under xeno-free conditions for the treatment of critical limb ischemia.
TGFβ1 and TGFβ2 proteins in corneas with and without stromal fibrosis: Delayed regeneration of apical epithelial growth factor barrier and the epithelial basement membrane in corneas with stromal fibrosis.
ADAM8 affects glioblastoma progression by regulating osteopontin-mediated angiogenesis.
Octyl Gallate Induces Pancreatic Ductal Adenocarcinoma Cell Apoptosis and Suppresses Endothelial-Mesenchymal Transition-Promoted M2-Macrophages, HSP90α Secretion, and Tumor Growth.
Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth.
Epithelial basement membrane injury and regeneration modulates corneal fibrosis after pseudomonas corneal ulcers in rabbits.
Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague.
Adipocyte progenitor cells initiate monocyte chemoattractant protein-1-mediated macrophage accumulation in visceral adipose tissue.
In vivo transcriptional profiling of Yersinia pestis reveals a novel bacterial mediator of pulmonary inflammation.
M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells.
Early host cell targets of Yersinia pestis during primary pneumonic plague.
Maternal immune stimulation during pregnancy shapes the immunological phenotype of offspring.
The stimulated innate resistance event in Bordetella pertussis infection is dependent on reactive oxygen species production.
CD40-activated B cells can efficiently prime antigen-specific naïve CD8+ T cells to generate effector but not memory T cells.
A2A adenosine receptor signaling in lymphocytes and the central nervous system regulates inflammation during experimental autoimmune encephalomyelitis.
NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation.
Outer membrane vesicles obtained from Bordetella pertussis Tohama expressing the lipid A deacylase PagL as a novel acellular vaccine candidate.
Production of IFN-β during Listeria monocytogenes infection is restricted to monocyte/macrophage lineage.
Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis.
Myeloid cells contribute to tumor lymphangiogenesis.
Chemokine receptor CXCR5 supports solitary intestinal lymphoid tissue formation, B cell homing, and induction of intestinal IgA responses.
A defect in Marco expression contributes to systemic lupus erythematosus development via failure to clear apoptotic cells.
Endogenous IL-17 does not play a significant role in the development of experimental murine allergic conjunctivitis.
Effective induction of anti-tumor immune responses with oligomannose-coated liposome targeting to intraperitoneal phagocytic cells.
A gene-dosage effect for interleukin-4 receptor alpha-chain expression has an impact on Th2-mediated allergic inflammation during bronchopulmonary mycosis.
IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans.
IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans.
Differential gene expression in functional classes of interstitial cells of Cajal in murine small intestine.
Postburn monocytes are the major producers of TNF-alpha in the heterogeneous splenic macrophage population.
Selective labeling and isolation of functional classes of interstitial cells of Cajal of human and murine small intestine.
TLR4, TLR9 and MyD88 are not required for the positive selection of autoreactive B cells into the primary repertoire.
Bone marrow mesenchymal stem cells suppress lymphocyte proliferation in vitro but fail to prevent graft-versus-host disease in mice.
Bone marrow mesenchymal stem cells suppress lymphocyte proliferation in vitro but fail to prevent graft-versus-host disease in mice.
Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses.
Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses.
Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection.
Redistributions of macrophages expressing the macrophage galactose-type C-type lectin (MGL) during antigen-induced chronic granulation tissue formation.
Lack of antigen-specific tissue remodeling in mice deficient in the macrophage galactose-type calcium-type lectin 1/CD301a.
Tick saliva inhibits differentiation, maturation and function of murine bone-marrow-derived dendritic cells.
Time-course expression of Toll-like receptors 2 and 4 in inflammatory bowel disease and homeostatic effect of VIP.
Granulation tissue formation by nonspecific inflammatory agent occurs independently of macrophage galactose-type C-type lectin-1.
Detection of antigen-specific T cells in experimental immune-mediated blepharoconjunctivitis in DO11.10 T cell receptor transgenic mice.
Detection of antigen-specific T cells in experimental immune-mediated blepharoconjunctivitis in DO11.10 T cell receptor transgenic mice.
Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice.
Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice.
In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C.
Protection against progressive leishmaniasis by IFN-beta.
Protection against progressive leishmaniasis by IFN-beta.
Control of Leishmania major in the absence of Tyk2 kinase.
Purification of interstitial cells of Cajal by fluorescence-activated cell sorting.
Quantitative analysis by flow cytometry of interstitial cells of Cajal, pacemakers, and mediators of neurotransmission in the gastrointestinal tract.
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis.
Modulation of interferon-induced genes by lipoxin analogue in anti-glomerular basement membrane nephritis.
Modulation of interferon-induced genes by lipoxin analogue in anti-glomerular basement membrane nephritis.
Macrophages and stromal cells phagocytose apoptotic bone marrow-derived B lineage cells.
Macrophages and stromal cells phagocytose apoptotic bone marrow-derived B lineage cells.
Organ-specific and stage-dependent control of Leishmania major infection by inducible nitric oxide synthase and phagocyte NADPH oxidase.
Granulocyte-dendritic cell unbalance in the non-obese diabetic mice.
Granulocyte-dendritic cell unbalance in the non-obese diabetic mice.
Butyric acid derivative induces allospecific T cell anergy and prevents graft-versus-host disease.
TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection.
TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection.
Induction of germinal centers by MMTV encoded superantigen on B cells.
Induction of germinal centers by MMTV encoded superantigen on B cells.
Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide.
Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide.
Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease.
Reduced oncogenicity of p190 Bcr/Abl F-actin-binding domain mutants.
Antigen-specific T helper cell function: differential cytokine expression in primary and memory responses.
Antigen-specific T helper cell function: differential cytokine expression in primary and memory responses.
Disruption of CD154:CD40 blocks generation of allograft immunity without affecting APC activation.
Evolution of antigen-specific T cell receptors in vivo: preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs.
Evolution of antigen-specific T cell receptors in vivo: preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs.
Depletion of CD8+ cells abolishes memory in acquired immunity against Chlamydia pneumoniae in BALB/c mice.
Depletion of CD8+ cells abolishes memory in acquired immunity against Chlamydia pneumoniae in BALB/c mice.
Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant mice.
Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant mice.
Antigen-driven selection of TCR In vivo: related TCR alpha-chains pair with diverse TCR beta-chains.
Comparison of erythropoietic response to androgen in young and old senescence accelerated mice.
Comparison of erythropoietic response to androgen in young and old senescence accelerated mice.
Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficient mice.
Abnormal myelocytic cell development in interleukin-2 (IL-2)-deficient mice: evidence for the involvement of IL-2 in myelopoiesis.
Growth hormone stimulates the proliferation of activated mouse T lymphocytes.
Targets of p56(lck) activity in immature thymoblasts: stimulation of the Ras/Raf/MAPK pathway.
Targets of p56(lck) activity in immature thymoblasts: stimulation of the Ras/Raf/MAPK pathway.
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.
BCR/ABL P210 and P190 cause distinct leukemia in transgenic mice.
Reactive oxygen intermediates in autoimmune islet cell destruction of the NOD mouse induced by peritoneal exudate cells (rich in macrophages) but not T cells.
Reactive oxygen intermediates in autoimmune islet cell destruction of the NOD mouse induced by peritoneal exudate cells (rich in macrophages) but not T cells.
Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations.
Retrovirus-induced immunodeficiency in mice exacerbates gastrointestinal candidiasis.
Retrovirus-induced immunodeficiency in mice exacerbates gastrointestinal candidiasis.
Enhanced resistance against Listeria monocytogenes achieved by pretreatment with granulocyte colony-stimulating factor.
Enhanced resistance against Listeria monocytogenes achieved by pretreatment with granulocyte colony-stimulating factor.
Mac-1: a macrophage differentiation antigen identified by monoclonal antibody.
Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens.
Pediaditakis I, Kodella KR, Manatakis DV, Le CY, Barthakur S, Sorets A, Gravanis A, Ewart L, Rubin LL, Manolakos ES, Hinojosa CD, Karalis K
iScience 2022 Aug 19;25(8):104813
iScience 2022 Aug 19;25(8):104813
Sourcing of human peripheral blood-derived myeloid angiogenic cells under xeno-free conditions for the treatment of critical limb ischemia.
Wong CWT, Sawhney A, Wu Y, Mak YW, Tian XY, Chan HF, Blocki A
Stem cell research & therapy 2022 Aug 13;13(1):419
Stem cell research & therapy 2022 Aug 13;13(1):419
TGFβ1 and TGFβ2 proteins in corneas with and without stromal fibrosis: Delayed regeneration of apical epithelial growth factor barrier and the epithelial basement membrane in corneas with stromal fibrosis.
de Oliveira RC, Tye G, Sampaio LP, Shiju TM, DeDreu J, Menko AS, Santhiago MR, Wilson SE
Experimental eye research 2021 Jan;202:108325
Experimental eye research 2021 Jan;202:108325
ADAM8 affects glioblastoma progression by regulating osteopontin-mediated angiogenesis.
Li Y, Guo S, Zhao K, Conrad C, Driescher C, Rothbart V, Schlomann U, Guerreiro H, Bopp MH, König A, Carl B, Pagenstecher A, Nimsky C, Bartsch JW
Biological chemistry 2021 Jan 27;402(2):195-206
Biological chemistry 2021 Jan 27;402(2):195-206
Octyl Gallate Induces Pancreatic Ductal Adenocarcinoma Cell Apoptosis and Suppresses Endothelial-Mesenchymal Transition-Promoted M2-Macrophages, HSP90α Secretion, and Tumor Growth.
Chua KV, Fan CS, Chen CC, Chen LL, Hsieh SC, Huang TS
Cells 2019 Dec 30;9(1)
Cells 2019 Dec 30;9(1)
Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth.
Klein JC, Moses K, Zelinskyy G, Sody S, Buer J, Lang S, Helfrich I, Dittmer U, Kirschning CJ, Brandau S
Nature communications 2017 Mar 16;8:14600
Nature communications 2017 Mar 16;8:14600
Epithelial basement membrane injury and regeneration modulates corneal fibrosis after pseudomonas corneal ulcers in rabbits.
Marino GK, Santhiago MR, Santhanam A, Lassance L, Thangavadivel S, Medeiros CS, Bose K, Tam KP, Wilson SE
Experimental eye research 2017 Aug;161:101-105
Experimental eye research 2017 Aug;161:101-105
Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague.
Stasulli NM, Eichelberger KR, Price PA, Pechous RD, Montgomery SA, Parker JS, Goldman WE
mBio 2015 Oct 13;6(5):e01530-15
mBio 2015 Oct 13;6(5):e01530-15
Adipocyte progenitor cells initiate monocyte chemoattractant protein-1-mediated macrophage accumulation in visceral adipose tissue.
Kaplan JL, Marshall MA, C McSkimming C, Harmon DB, Garmey JC, Oldham SN, Hallowell P, McNamara CA
Molecular metabolism 2015 Nov;4(11):779-94
Molecular metabolism 2015 Nov;4(11):779-94
In vivo transcriptional profiling of Yersinia pestis reveals a novel bacterial mediator of pulmonary inflammation.
Pechous RD, Broberg CA, Stasulli NM, Miller VL, Goldman WE
mBio 2015 Feb 17;6(1):e02302-14
mBio 2015 Feb 17;6(1):e02302-14
M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells.
Döring M, Lessin I, Frenz T, Spanier J, Kessler A, Tegtmeyer P, Dağ F, Thiel N, Trilling M, Lienenklaus S, Weiss S, Scheu S, Messerle M, Cicin-Sain L, Hengel H, Kalinke U
Journal of virology 2014 Dec;88(23):13638-50
Journal of virology 2014 Dec;88(23):13638-50
Early host cell targets of Yersinia pestis during primary pneumonic plague.
Pechous RD, Sivaraman V, Price PA, Stasulli NM, Goldman WE
PLoS pathogens 2013;9(10):e1003679
PLoS pathogens 2013;9(10):e1003679
Maternal immune stimulation during pregnancy shapes the immunological phenotype of offspring.
Mandal M, Donnelly R, Elkabes S, Zhang P, Davini D, David BT, Ponzio NM
Brain, behavior, and immunity 2013 Oct;33:33-45
Brain, behavior, and immunity 2013 Oct;33:33-45
The stimulated innate resistance event in Bordetella pertussis infection is dependent on reactive oxygen species production.
Zurita E, Moreno G, Errea A, Ormazabal M, Rumbo M, Hozbor D
Infection and immunity 2013 Jul;81(7):2371-8
Infection and immunity 2013 Jul;81(7):2371-8
CD40-activated B cells can efficiently prime antigen-specific naïve CD8+ T cells to generate effector but not memory T cells.
Mathieu M, Cotta-Grand N, Daudelin JF, Boulet S, Lapointe R, Labrecque N
PloS one 2012;7(1):e30139
PloS one 2012;7(1):e30139
A2A adenosine receptor signaling in lymphocytes and the central nervous system regulates inflammation during experimental autoimmune encephalomyelitis.
Mills JH, Kim DG, Krenz A, Chen JF, Bynoe MS
Journal of immunology (Baltimore, Md. : 1950) 2012 Jun 1;188(11):5713-22
Journal of immunology (Baltimore, Md. : 1950) 2012 Jun 1;188(11):5713-22
NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation.
Haworth O, Cernadas M, Levy BD
Journal of immunology (Baltimore, Md. : 1950) 2011 Jun 1;186(11):6129-35
Journal of immunology (Baltimore, Md. : 1950) 2011 Jun 1;186(11):6129-35
Outer membrane vesicles obtained from Bordetella pertussis Tohama expressing the lipid A deacylase PagL as a novel acellular vaccine candidate.
Asensio CJ, Gaillard ME, Moreno G, Bottero D, Zurita E, Rumbo M, van der Ley P, van der Ark A, Hozbor D
Vaccine 2011 Feb 11;29(8):1649-56
Vaccine 2011 Feb 11;29(8):1649-56
Production of IFN-β during Listeria monocytogenes infection is restricted to monocyte/macrophage lineage.
Solodova E, Jablonska J, Weiss S, Lienenklaus S
PloS one 2011 Apr 11;6(4):e18543
PloS one 2011 Apr 11;6(4):e18543
Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis.
Siegemund S, Hartl A, von Buttlar H, Dautel F, Raue R, Freudenberg MA, Fejer G, Büttner M, Köhler G, Kirschning CJ, Sparwasser T, Alber G
Journal of virology 2009 Sep;83(18):9411-22
Journal of virology 2009 Sep;83(18):9411-22
Myeloid cells contribute to tumor lymphangiogenesis.
Zumsteg A, Baeriswyl V, Imaizumi N, Schwendener R, Rüegg C, Christofori G
PloS one 2009 Sep 17;4(9):e7067
PloS one 2009 Sep 17;4(9):e7067
Chemokine receptor CXCR5 supports solitary intestinal lymphoid tissue formation, B cell homing, and induction of intestinal IgA responses.
Velaga S, Herbrand H, Friedrichsen M, Jiong T, Dorsch M, Hoffmann MW, Förster R, Pabst O
Journal of immunology (Baltimore, Md. : 1950) 2009 Mar 1;182(5):2610-9
Journal of immunology (Baltimore, Md. : 1950) 2009 Mar 1;182(5):2610-9
A defect in Marco expression contributes to systemic lupus erythematosus development via failure to clear apoptotic cells.
Rogers NJ, Lees MJ, Gabriel L, Maniati E, Rose SJ, Potter PK, Morley BJ
Journal of immunology (Baltimore, Md. : 1950) 2009 Feb 15;182(4):1982-90
Journal of immunology (Baltimore, Md. : 1950) 2009 Feb 15;182(4):1982-90
Endogenous IL-17 does not play a significant role in the development of experimental murine allergic conjunctivitis.
Fukushima A, Sumi T, Ishida W, Yamada J, Iwakura Y, Ueno H
International archives of allergy and immunology 2008;147(3):206-12
International archives of allergy and immunology 2008;147(3):206-12
Effective induction of anti-tumor immune responses with oligomannose-coated liposome targeting to intraperitoneal phagocytic cells.
Ikehara Y, Shiuchi N, Kabata-Ikehara S, Nakanishi H, Yokoyama N, Takagi H, Nagata T, Koide Y, Kuzushima K, Takahashi T, Tsujimura K, Kojima N
Cancer letters 2008 Feb 18;260(1-2):137-45
Cancer letters 2008 Feb 18;260(1-2):137-45
A gene-dosage effect for interleukin-4 receptor alpha-chain expression has an impact on Th2-mediated allergic inflammation during bronchopulmonary mycosis.
Müller U, Stenzel W, Köhler G, Polte T, Blessing M, Mann A, Piehler D, Brombacher F, Alber G
The Journal of infectious diseases 2008 Dec 1;198(11):1714-21
The Journal of infectious diseases 2008 Dec 1;198(11):1714-21
IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans.
Müller U, Stenzel W, Köhler G, Werner C, Polte T, Hansen G, Schütze N, Straubinger RK, Blessing M, McKenzie AN, Brombacher F, Alber G
Journal of immunology (Baltimore, Md. : 1950) 2007 Oct 15;179(8):5367-77
Journal of immunology (Baltimore, Md. : 1950) 2007 Oct 15;179(8):5367-77
IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans.
Müller U, Stenzel W, Köhler G, Werner C, Polte T, Hansen G, Schütze N, Straubinger RK, Blessing M, McKenzie AN, Brombacher F, Alber G
Journal of immunology (Baltimore, Md. : 1950) 2007 Oct 15;179(8):5367-77
Journal of immunology (Baltimore, Md. : 1950) 2007 Oct 15;179(8):5367-77
Differential gene expression in functional classes of interstitial cells of Cajal in murine small intestine.
Chen H, Ordög T, Chen J, Young DL, Bardsley MR, Redelman D, Ward SM, Sanders KM
Physiological genomics 2007 Nov 14;31(3):492-509
Physiological genomics 2007 Nov 14;31(3):492-509
Postburn monocytes are the major producers of TNF-alpha in the heterogeneous splenic macrophage population.
Noel G, Guo X, Wang Q, Schwemberger S, Byrum D, Ogle C
Shock (Augusta, Ga.) 2007 Mar;27(3):312-9
Shock (Augusta, Ga.) 2007 Mar;27(3):312-9
Selective labeling and isolation of functional classes of interstitial cells of Cajal of human and murine small intestine.
Chen H, Redelman D, Ro S, Ward SM, Ordög T, Sanders KM
American journal of physiology. Cell physiology 2007 Jan;292(1):C497-507
American journal of physiology. Cell physiology 2007 Jan;292(1):C497-507
TLR4, TLR9 and MyD88 are not required for the positive selection of autoreactive B cells into the primary repertoire.
Silver K, Ferry H, Crockford T, Cornall RJ
European journal of immunology 2006 Jun;36(6):1404-12
European journal of immunology 2006 Jun;36(6):1404-12
Bone marrow mesenchymal stem cells suppress lymphocyte proliferation in vitro but fail to prevent graft-versus-host disease in mice.
Sudres M, Norol F, Trenado A, Grégoire S, Charlotte F, Levacher B, Lataillade JJ, Bourin P, Holy X, Vernant JP, Klatzmann D, Cohen JL
Journal of immunology (Baltimore, Md. : 1950) 2006 Jun 15;176(12):7761-7
Journal of immunology (Baltimore, Md. : 1950) 2006 Jun 15;176(12):7761-7
Bone marrow mesenchymal stem cells suppress lymphocyte proliferation in vitro but fail to prevent graft-versus-host disease in mice.
Sudres M, Norol F, Trenado A, Grégoire S, Charlotte F, Levacher B, Lataillade JJ, Bourin P, Holy X, Vernant JP, Klatzmann D, Cohen JL
Journal of immunology (Baltimore, Md. : 1950) 2006 Jun 15;176(12):7761-7
Journal of immunology (Baltimore, Md. : 1950) 2006 Jun 15;176(12):7761-7
Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses.
Grisaru D, Pick M, Perry C, Sklan EH, Almog R, Goldberg I, Naparstek E, Lessing JB, Soreq H, Deutsch V
Journal of immunology (Baltimore, Md. : 1950) 2006 Jan 1;176(1):27-35
Journal of immunology (Baltimore, Md. : 1950) 2006 Jan 1;176(1):27-35
Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses.
Grisaru D, Pick M, Perry C, Sklan EH, Almog R, Goldberg I, Naparstek E, Lessing JB, Soreq H, Deutsch V
Journal of immunology (Baltimore, Md. : 1950) 2006 Jan 1;176(1):27-35
Journal of immunology (Baltimore, Md. : 1950) 2006 Jan 1;176(1):27-35
Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection.
Haque A, Easton A, Smith D, O'Garra A, Van Rooijen N, Lertmemongkolchai G, Titball RW, Bancroft GJ
The Journal of infectious diseases 2006 Feb 1;193(3):370-9
The Journal of infectious diseases 2006 Feb 1;193(3):370-9
Redistributions of macrophages expressing the macrophage galactose-type C-type lectin (MGL) during antigen-induced chronic granulation tissue formation.
Sato K, Imai Y, Higashi N, Kumamoto Y, Mukaida N, Irimura T
International immunology 2005 May;17(5):559-68
International immunology 2005 May;17(5):559-68
Lack of antigen-specific tissue remodeling in mice deficient in the macrophage galactose-type calcium-type lectin 1/CD301a.
Sato K, Imai Y, Higashi N, Kumamoto Y, Onami TM, Hedrick SM, Irimura T
Blood 2005 Jul 1;106(1):207-15
Blood 2005 Jul 1;106(1):207-15
Tick saliva inhibits differentiation, maturation and function of murine bone-marrow-derived dendritic cells.
Cavassani KA, Aliberti JC, Dias AR, Silva JS, Ferreira BR
Immunology 2005 Feb;114(2):235-45
Immunology 2005 Feb;114(2):235-45
Time-course expression of Toll-like receptors 2 and 4 in inflammatory bowel disease and homeostatic effect of VIP.
Gomariz RP, Arranz A, Abad C, Torroba M, Martinez C, Rosignoli F, Garcia-Gómez M, Leceta J, Juarranz Y
Journal of leukocyte biology 2005 Aug;78(2):491-502
Journal of leukocyte biology 2005 Aug;78(2):491-502
Granulation tissue formation by nonspecific inflammatory agent occurs independently of macrophage galactose-type C-type lectin-1.
Sato K, Komatsu N, Higashi N, Imai Y, Irimura T
Clinical immunology (Orlando, Fla.) 2005 Apr;115(1):47-50
Clinical immunology (Orlando, Fla.) 2005 Apr;115(1):47-50
Detection of antigen-specific T cells in experimental immune-mediated blepharoconjunctivitis in DO11.10 T cell receptor transgenic mice.
Ozaki A, Ishida W, Fukata K, Fukushima A, Ueno H
Microbiology and immunology 2004;48(1):39-48
Microbiology and immunology 2004;48(1):39-48
Detection of antigen-specific T cells in experimental immune-mediated blepharoconjunctivitis in DO11.10 T cell receptor transgenic mice.
Ozaki A, Ishida W, Fukata K, Fukushima A, Ueno H
Microbiology and immunology 2004;48(1):39-48
Microbiology and immunology 2004;48(1):39-48
Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice.
Zheng SJ, Jiang J, Shen H, Chen YH
Journal of immunology (Baltimore, Md. : 1950) 2004 Nov 1;173(9):5652-8
Journal of immunology (Baltimore, Md. : 1950) 2004 Nov 1;173(9):5652-8
Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice.
Zheng SJ, Jiang J, Shen H, Chen YH
Journal of immunology (Baltimore, Md. : 1950) 2004 Nov 1;173(9):5652-8
Journal of immunology (Baltimore, Md. : 1950) 2004 Nov 1;173(9):5652-8
In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C.
Yuan Y, Shen H, Franklin DS, Scadden DT, Cheng T
Nature cell biology 2004 May;6(5):436-42
Nature cell biology 2004 May;6(5):436-42
Protection against progressive leishmaniasis by IFN-beta.
Mattner J, Wandersee-Steinhäuser A, Pahl A, Röllinghoff M, Majeau GR, Hochman PS, Bogdan C
Journal of immunology (Baltimore, Md. : 1950) 2004 Jun 15;172(12):7574-82
Journal of immunology (Baltimore, Md. : 1950) 2004 Jun 15;172(12):7574-82
Protection against progressive leishmaniasis by IFN-beta.
Mattner J, Wandersee-Steinhäuser A, Pahl A, Röllinghoff M, Majeau GR, Hochman PS, Bogdan C
Journal of immunology (Baltimore, Md. : 1950) 2004 Jun 15;172(12):7574-82
Journal of immunology (Baltimore, Md. : 1950) 2004 Jun 15;172(12):7574-82
Control of Leishmania major in the absence of Tyk2 kinase.
Schleicher U, Mattner J, Blos M, Schindler H, Röllinghoff M, Karaghiosoff M, Müller M, Werner-Felmayer G, Bogdan C
European journal of immunology 2004 Feb;34(2):519-29
European journal of immunology 2004 Feb;34(2):519-29
Purification of interstitial cells of Cajal by fluorescence-activated cell sorting.
Ordög T, Redelman D, Miller LJ, Horváth VJ, Zhong Q, Almeida-Porada G, Zanjani ED, Horowitz B, Sanders KM
American journal of physiology. Cell physiology 2004 Feb;286(2):C448-56
American journal of physiology. Cell physiology 2004 Feb;286(2):C448-56
Quantitative analysis by flow cytometry of interstitial cells of Cajal, pacemakers, and mediators of neurotransmission in the gastrointestinal tract.
Ordög T, Redelman D, Horváth VJ, Miller LJ, Horowitz B, Sanders KM
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2004 Dec;62(2):139-49
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2004 Dec;62(2):139-49
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis.
Wang T, Town T, Alexopoulou L, Anderson JF, Fikrig E, Flavell RA
Nature medicine 2004 Dec;10(12):1366-73
Nature medicine 2004 Dec;10(12):1366-73
Modulation of interferon-induced genes by lipoxin analogue in anti-glomerular basement membrane nephritis.
Ohse T, Ota T, Kieran N, Godson C, Yamada K, Tanaka T, Fujita T, Nangaku M
Journal of the American Society of Nephrology : JASN 2004 Apr;15(4):919-27
Journal of the American Society of Nephrology : JASN 2004 Apr;15(4):919-27
Modulation of interferon-induced genes by lipoxin analogue in anti-glomerular basement membrane nephritis.
Ohse T, Ota T, Kieran N, Godson C, Yamada K, Tanaka T, Fujita T, Nangaku M
Journal of the American Society of Nephrology : JASN 2004 Apr;15(4):919-27
Journal of the American Society of Nephrology : JASN 2004 Apr;15(4):919-27
Macrophages and stromal cells phagocytose apoptotic bone marrow-derived B lineage cells.
Dogusan Z, Montecino-Rodriguez E, Dorshkind K
Journal of immunology (Baltimore, Md. : 1950) 2004 Apr 15;172(8):4717-23
Journal of immunology (Baltimore, Md. : 1950) 2004 Apr 15;172(8):4717-23
Macrophages and stromal cells phagocytose apoptotic bone marrow-derived B lineage cells.
Dogusan Z, Montecino-Rodriguez E, Dorshkind K
Journal of immunology (Baltimore, Md. : 1950) 2004 Apr 15;172(8):4717-23
Journal of immunology (Baltimore, Md. : 1950) 2004 Apr 15;172(8):4717-23
Organ-specific and stage-dependent control of Leishmania major infection by inducible nitric oxide synthase and phagocyte NADPH oxidase.
Blos M, Schleicher U, Soares Rocha FJ, Meissner U, Röllinghoff M, Bogdan C
European journal of immunology 2003 May;33(5):1224-34
European journal of immunology 2003 May;33(5):1224-34
Granulocyte-dendritic cell unbalance in the non-obese diabetic mice.
Morin J, Chimènes A, Boitard C, Berthier R, Boudaly S
Cellular immunology 2003 May;223(1):13-25
Cellular immunology 2003 May;223(1):13-25
Granulocyte-dendritic cell unbalance in the non-obese diabetic mice.
Morin J, Chimènes A, Boitard C, Berthier R, Boudaly S
Cellular immunology 2003 May;223(1):13-25
Cellular immunology 2003 May;223(1):13-25
Butyric acid derivative induces allospecific T cell anergy and prevents graft-versus-host disease.
Gilbert KM, Boger S, Fifer EK
Immunopharmacology and immunotoxicology 2003 Feb;25(1):13-27
Immunopharmacology and immunotoxicology 2003 Feb;25(1):13-27
TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection.
Roach DR, Bean AG, Demangel C, France MP, Briscoe H, Britton WJ
Journal of immunology (Baltimore, Md. : 1950) 2002 May 1;168(9):4620-7
Journal of immunology (Baltimore, Md. : 1950) 2002 May 1;168(9):4620-7
TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection.
Roach DR, Bean AG, Demangel C, France MP, Briscoe H, Britton WJ
Journal of immunology (Baltimore, Md. : 1950) 2002 May 1;168(9):4620-7
Journal of immunology (Baltimore, Md. : 1950) 2002 May 1;168(9):4620-7
Induction of germinal centers by MMTV encoded superantigen on B cells.
Simmons WJ, Simms M, Chiarle R, Mackay F, Tsiagbe VK, Browning J, Inghirami G, Thorbecke GJ
Developmental immunology 2001;8(3-4):201-11
Developmental immunology 2001;8(3-4):201-11
Induction of germinal centers by MMTV encoded superantigen on B cells.
Simmons WJ, Simms M, Chiarle R, Mackay F, Tsiagbe VK, Browning J, Inghirami G, Thorbecke GJ
Developmental immunology 2001;8(3-4):201-11
Developmental immunology 2001;8(3-4):201-11
Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide.
Saio M, Radoja S, Marino M, Frey AB
Journal of immunology (Baltimore, Md. : 1950) 2001 Nov 15;167(10):5583-93
Journal of immunology (Baltimore, Md. : 1950) 2001 Nov 15;167(10):5583-93
Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide.
Saio M, Radoja S, Marino M, Frey AB
Journal of immunology (Baltimore, Md. : 1950) 2001 Nov 15;167(10):5583-93
Journal of immunology (Baltimore, Md. : 1950) 2001 Nov 15;167(10):5583-93
Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease.
Matsuoka Y, Picciano M, Malester B, LaFrancois J, Zehr C, Daeschner JM, Olschowka JA, Fonseca MI, O'Banion MK, Tenner AJ, Lemere CA, Duff K
The American journal of pathology 2001 Apr;158(4):1345-54
The American journal of pathology 2001 Apr;158(4):1345-54
Reduced oncogenicity of p190 Bcr/Abl F-actin-binding domain mutants.
Heisterkamp N, Voncken JW, Senadheera D, Gonzalez-Gomez I, Reichert A, Haataja L, Reinikainen A, Pattengale PK, Groffen J
Blood 2000 Sep 15;96(6):2226-32
Blood 2000 Sep 15;96(6):2226-32
Antigen-specific T helper cell function: differential cytokine expression in primary and memory responses.
Panus JF, McHeyzer-Williams LJ, McHeyzer-Williams MG
The Journal of experimental medicine 2000 Nov 6;192(9):1301-16
The Journal of experimental medicine 2000 Nov 6;192(9):1301-16
Antigen-specific T helper cell function: differential cytokine expression in primary and memory responses.
Panus JF, McHeyzer-Williams LJ, McHeyzer-Williams MG
The Journal of experimental medicine 2000 Nov 6;192(9):1301-16
The Journal of experimental medicine 2000 Nov 6;192(9):1301-16
Disruption of CD154:CD40 blocks generation of allograft immunity without affecting APC activation.
Shepherd DM, Kerkvliet NI
Journal of immunology (Baltimore, Md. : 1950) 1999 Sep 1;163(5):2470-7
Journal of immunology (Baltimore, Md. : 1950) 1999 Sep 1;163(5):2470-7
Evolution of antigen-specific T cell receptors in vivo: preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs.
McHeyzer-Williams LJ, Panus JF, Mikszta JA, McHeyzer-Williams MG
The Journal of experimental medicine 1999 Jun 7;189(11):1823-38
The Journal of experimental medicine 1999 Jun 7;189(11):1823-38
Evolution of antigen-specific T cell receptors in vivo: preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs.
McHeyzer-Williams LJ, Panus JF, Mikszta JA, McHeyzer-Williams MG
The Journal of experimental medicine 1999 Jun 7;189(11):1823-38
The Journal of experimental medicine 1999 Jun 7;189(11):1823-38
Depletion of CD8+ cells abolishes memory in acquired immunity against Chlamydia pneumoniae in BALB/c mice.
Penttilä JM, Anttila M, Varkila K, Puolakkainen M, Sarvas M, Mäkelä PH, Rautonen N
Immunology 1999 Jul;97(3):490-6
Immunology 1999 Jul;97(3):490-6
Depletion of CD8+ cells abolishes memory in acquired immunity against Chlamydia pneumoniae in BALB/c mice.
Penttilä JM, Anttila M, Varkila K, Puolakkainen M, Sarvas M, Mäkelä PH, Rautonen N
Immunology 1999 Jul;97(3):490-6
Immunology 1999 Jul;97(3):490-6
Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant mice.
Rodewald HR, Brocker T, Haller C
Proceedings of the National Academy of Sciences of the United States of America 1999 Dec 21;96(26):15068-73
Proceedings of the National Academy of Sciences of the United States of America 1999 Dec 21;96(26):15068-73
Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant mice.
Rodewald HR, Brocker T, Haller C
Proceedings of the National Academy of Sciences of the United States of America 1999 Dec 21;96(26):15068-73
Proceedings of the National Academy of Sciences of the United States of America 1999 Dec 21;96(26):15068-73
Antigen-driven selection of TCR In vivo: related TCR alpha-chains pair with diverse TCR beta-chains.
Mikszta JA, McHeyzer-Williams LJ, McHeyzer-Williams MG
Journal of immunology (Baltimore, Md. : 1950) 1999 Dec 1;163(11):5978-88
Journal of immunology (Baltimore, Md. : 1950) 1999 Dec 1;163(11):5978-88
Comparison of erythropoietic response to androgen in young and old senescence accelerated mice.
Saitoh T, Morimoto K, Kumagai T, Tsuboi I, Aikawa S, Horie T
Mechanisms of ageing and development 1999 Aug 30;109(2):125-39
Mechanisms of ageing and development 1999 Aug 30;109(2):125-39
Comparison of erythropoietic response to androgen in young and old senescence accelerated mice.
Saitoh T, Morimoto K, Kumagai T, Tsuboi I, Aikawa S, Horie T
Mechanisms of ageing and development 1999 Aug 30;109(2):125-39
Mechanisms of ageing and development 1999 Aug 30;109(2):125-39
Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficient mice.
Contractor NV, Bassiri H, Reya T, Park AY, Baumgart DC, Wasik MA, Emerson SG, Carding SR
Journal of immunology (Baltimore, Md. : 1950) 1998 Jan 1;160(1):385-94
Journal of immunology (Baltimore, Md. : 1950) 1998 Jan 1;160(1):385-94
Abnormal myelocytic cell development in interleukin-2 (IL-2)-deficient mice: evidence for the involvement of IL-2 in myelopoiesis.
Reya T, Contractor NV, Couzens MS, Wasik MA, Emerson SG, Carding SR
Blood 1998 Apr 15;91(8):2935-47
Blood 1998 Apr 15;91(8):2935-47
Growth hormone stimulates the proliferation of activated mouse T lymphocytes.
Postel-Vinay MC, de Mello Coelho V, Gagnerault MC, Dardenne M
Endocrinology 1997 May;138(5):1816-20
Endocrinology 1997 May;138(5):1816-20
Targets of p56(lck) activity in immature thymoblasts: stimulation of the Ras/Raf/MAPK pathway.
Lin K, Abraham KM
International immunology 1997 Feb;9(2):291-306
International immunology 1997 Feb;9(2):291-306
Targets of p56(lck) activity in immature thymoblasts: stimulation of the Ras/Raf/MAPK pathway.
Lin K, Abraham KM
International immunology 1997 Feb;9(2):291-306
International immunology 1997 Feb;9(2):291-306
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.
Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC
The Journal of experimental medicine 1996 Apr 1;183(4):1797-806
The Journal of experimental medicine 1996 Apr 1;183(4):1797-806
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.
Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC
The Journal of experimental medicine 1996 Apr 1;183(4):1797-806
The Journal of experimental medicine 1996 Apr 1;183(4):1797-806
BCR/ABL P210 and P190 cause distinct leukemia in transgenic mice.
Voncken JW, Kaartinen V, Pattengale PK, Germeraad WT, Groffen J, Heisterkamp N
Blood 1995 Dec 15;86(12):4603-11
Blood 1995 Dec 15;86(12):4603-11
Reactive oxygen intermediates in autoimmune islet cell destruction of the NOD mouse induced by peritoneal exudate cells (rich in macrophages) but not T cells.
Horio F, Fukuda M, Katoh H, Petruzzelli M, Yano N, Rittershaus C, Bonner-Weir S, Hattori M
Diabetologia 1994 Jan;37(1):22-31
Diabetologia 1994 Jan;37(1):22-31
Reactive oxygen intermediates in autoimmune islet cell destruction of the NOD mouse induced by peritoneal exudate cells (rich in macrophages) but not T cells.
Horio F, Fukuda M, Katoh H, Petruzzelli M, Yano N, Rittershaus C, Bonner-Weir S, Hattori M
Diabetologia 1994 Jan;37(1):22-31
Diabetologia 1994 Jan;37(1):22-31
Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations.
Gagnerault MC, Touraine P, Savino W, Kelly PA, Dardenne M
Journal of immunology (Baltimore, Md. : 1950) 1993 Jun 15;150(12):5673-81
Journal of immunology (Baltimore, Md. : 1950) 1993 Jun 15;150(12):5673-81
Retrovirus-induced immunodeficiency in mice exacerbates gastrointestinal candidiasis.
Cole GT, Saha K, Seshan KR, Lynn KT, Franco M, Wong PK
Infection and immunity 1992 Oct;60(10):4168-78
Infection and immunity 1992 Oct;60(10):4168-78
Retrovirus-induced immunodeficiency in mice exacerbates gastrointestinal candidiasis.
Cole GT, Saha K, Seshan KR, Lynn KT, Franco M, Wong PK
Infection and immunity 1992 Oct;60(10):4168-78
Infection and immunity 1992 Oct;60(10):4168-78
Enhanced resistance against Listeria monocytogenes achieved by pretreatment with granulocyte colony-stimulating factor.
Shinomiya N, Tsuru S, Katsura Y, Kayashima S, Nomoto K
Infection and immunity 1991 Dec;59(12):4740-3
Infection and immunity 1991 Dec;59(12):4740-3
Enhanced resistance against Listeria monocytogenes achieved by pretreatment with granulocyte colony-stimulating factor.
Shinomiya N, Tsuru S, Katsura Y, Kayashima S, Nomoto K
Infection and immunity 1991 Dec;59(12):4740-3
Infection and immunity 1991 Dec;59(12):4740-3
Mac-1: a macrophage differentiation antigen identified by monoclonal antibody.
Springer T, Galfré G, Secher DS, Milstein C
European journal of immunology 1979 Apr;9(4):301-6
European journal of immunology 1979 Apr;9(4):301-6
Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens.
Springer T, Galfrè G, Secher DS, Milstein C
European journal of immunology 1978 Aug;8(8):539-51
European journal of immunology 1978 Aug;8(8):539-51
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- Representative images of immunohistochemically stained murine gastrocnemius muscle for CD31 (green) and CD11b (red) ( n = 6). A DAPI was used to visualize nuclei staining (blue). B Quantification of CD11b- and C CD31-stained area of histological sections of muscle tissue derived from mice in the MSCs and BDACs treatment and vehicle groups
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- Reconstruction of the neurovascular unit in the Brain-Chip (A) Schematic illustration of the Brain-Chip, a two-channel microengineered chip including iPSC-derived brain endothelial-like cells cultured on all surfaces of the bottom channel, and iPSC-derived Glutamatergic and GABAergic neurons, primary human brain astrocytes, pericytes, and microglia on the surface of the top channel. (B) Confocal images of the cell coverage in the brain channel on day 7 of culture. Top image: Immunofluorescence staining of the brain channel including MAP2 (green), GFAP (magenta), NG2 (red), and DAPI (blue). Bottom images: Representative merged confocal image of the brain channel on culture day 7, stained for neurons (MAP2, green), astrocytes (GFAP, magenta, IBA1, yellow), and pericytes (alphaSMA, red) (bar, 50 mum). (C) Representative immunofluorescent staining for s100beta (red) and GLAST (green) (bar,100 mum). (D) FACS analysis of cell-specific markers of microglia: Total population of microglia within the brain channel (gray), CD11b-positive population (magenta), CD45-positive population (magenta), quantification of CD11b:CD45-positive cells. (E) Representative merged confocal image of the brain channel co-stained with VGAT (green) for GABAergic neurons and VGlut1 (red) for Glutamatergic neurons (bar, 100 mum). (F) Immunofluorescence staining of the brain channel including MAP2 (green) and SYP (red) (bar, 100 mum). (G) Levels of secreted glutamate in the brain channel on culture days 5, 6,
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- Figure 5 OG inhibits tumor growth, M2-type macrophages, and serum HSP90alpha levels in Panc 02 + EndoMT tumor model. ( A ) Measurement of the superficial tumor volumes from the C57BL/6 mice subcutaneously inoculated with Panc 02 + EndoMT cell grafts and treated with OG or control 40% PEG400 (CTRL). The measurement was started on Day 13 post-inoculation and continued every 3 days using Vernier caliper with the formula 1/2 x length x width 2 . ( B ) Tumors removed from the mice described in (A) on Day 32 post-inoculation. OG treatment significantly inhibited the tumor growth of Panc 02 + EndoMT cell grafts. ( C ) Representative H&E-stained tumor tissue sections of control and OG-treated mice. OG treatment did not obviously cause loosened cell arrangement and decreased chromatin basophilia which were observed in the Panc 02 tumor model. ( D ) Immunohistochemical staining of CK18 and alpha-SMA from the tumor tissues of control or OG-treated mice. OG treatment did not significantly change the CK18 + and alpha-SMA + cell levels of tumor tissues. ( E ) Immunohistochemical staining of CD11b + , F4/80 + , and CD163 + cells from the tumor tissues of control or OG-treated mice. ( F ) Quantitation of the levels of CD11b + , F4/80 + , and CD163 + cells from the tumor tissues of control or OG-treated mice. OG treatment caused a significant increase of F4/80 + macrophages but decreases of CD11b + myeloid cells and CD163 + macrophages in the tumor tissues. ( G ) Serum HSP90alpha level