301315

antibody from BioLegend

Targeting: ITGAM CD11B, CR3A, MAC-1

Antibody data

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Validation data

Product number: 301315 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#301315, RRID:AB_493015
Product name: Pacific Blue™ anti-human CD11b [ICRF44]
Antibody type: Monoclonal
Antigen: CD11b
Description: CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and Factor X.
Reactivity: Human, Porcine, Simian
Host: Mouse
Conjugate: Blue dye
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

ITGAM protein structure - 301315 shown in red.