Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- ELISA [1]
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Validation data
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- Product number
- H00000873-M01 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#H00000873-M01, RRID:AB_425345
- Product name
- CBR1 monoclonal antibody (M01), clone 4G11-1C7
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against a full length recombinant CBR1.
- Antigen sequence
MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVL
TARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSI
RALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHI
QAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSS
IMSVRALKSCSPELQQKFRSETITEEELVGLMNKF
VEDTKKGVHQKEGWPSSAYGVTKIGVTVLSRIHAR
KLSEQRKGDKILLNACCPGWVRTDMAGPKATKSPE
EGAETPVYLALLPPDAEGPHGQFVSEKRVEQW- Isotype
- IgG
- Antibody clone number
- 4G11-1C7
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Submitted references Two nonsynonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin.
Bains OS, Karkling MJ, Grigliatti TA, Reid RE, Riggs KW
Drug metabolism and disposition: the biological fate of chemicals 2009 May;37(5):1107-14
Drug metabolism and disposition: the biological fate of chemicals 2009 May;37(5):1107-14
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Detection limit for recombinant GST tagged CBR1 is approximately 1ng/ml as a capture antibody.
- Validation comment
- Sandwich ELISA (Recombinant protein)
- Protocol
- Protocol