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- References [3]
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- Product number
- OST00025W - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- TRPC4 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Reactivity
- Human, Mouse, Rat
- Host
- Sheep
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- Conc. Not Determined
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Submitted references Transient Receptor Potential Channel 4 Small-Molecule Inhibition Alleviates Migraine-Like Behavior in Mice.
Sensory Neuron-Expressed TRPC4 Is a Target for the Relief of Psoriasiform Itch and Skin Inflammation in Mice.
Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice.
Cohen CF, Prudente AS, Berta T, Lee SH
Frontiers in molecular neuroscience 2021;14:765181
Frontiers in molecular neuroscience 2021;14:765181
Sensory Neuron-Expressed TRPC4 Is a Target for the Relief of Psoriasiform Itch and Skin Inflammation in Mice.
Lee SH, Tonello R, Choi Y, Jung SJ, Berta T
The Journal of investigative dermatology 2020 Nov;140(11):2221-2229.e6
The Journal of investigative dermatology 2020 Nov;140(11):2221-2229.e6
Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice.
Lee SH, Cho PS, Tonello R, Lee HK, Jang JH, Park GY, Hwang SW, Park CK, Jung SJ, Berta T
The Journal of allergy and clinical immunology 2018 Oct;142(4):1349-1352.e16
The Journal of allergy and clinical immunology 2018 Oct;142(4):1349-1352.e16
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- FIGURE 2 Characterization of TRPC4 expression in trigeminal ganglia (TG) tissue. (A) Illustration of the TG and its three branches (V1-V3) innervating the head and face, and TRPC4 immunofluorescence (green) in the V1, V2, and V3 areas. DAPI (blue) was used as tissue counterstaining. (B) Transcriptional analysis of the TRPCs in TG tissues from male and female mice. GAPDH was used as the housekeeping gene. n = 4-6 mice/sex/group.
