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- References [7]
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- Product number
- ABIN2484779 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 329-530) antibody (Alkaline Phosphatase (AP))
- Antibody type
- Monoclonal
- Description
- Protein G Purified
- Reactivity
- Human, Mouse, Rat, Bovine
- Host
- Mouse
- Epitope
- AA 329-530
- Isotype
- IgG
- Antibody clone number
- ESEE122
- Vial size
- 100 μg
- Storage
- -20°C
Submitted references HIF1 and oxygen sensing in the brain.
Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells.
HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression.
Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1.
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
Sharp FR, Bernaudin M
Nature reviews. Neuroscience 2004 Jun;5(6):437-48
Nature reviews. Neuroscience 2004 Jun;5(6):437-48
Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells.
Fukuda R, Hirota K, Fan F, Jung YD, Ellis LM, Semenza GL
The Journal of biological chemistry 2002 Oct 11;277(41):38205-11
The Journal of biological chemistry 2002 Oct 11;277(41):38205-11
HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression.
Laughner E, Taghavi P, Chiles K, Mahon PC, Semenza GL
Molecular and cellular biology 2001 Jun;21(12):3995-4004
Molecular and cellular biology 2001 Jun;21(12):3995-4004
Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1.
Jiang BH, Jiang G, Zheng JZ, Lu Z, Hunter T, Vogt PK
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001 Jul;12(7):363-9
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001 Jul;12(7):363-9
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, von Kriegsheim A, Hebestreit HF, Mukherji M, Schofield CJ, Maxwell PH, Pugh CW, Ratcliffe PJ
Science (New York, N.Y.) 2001 Apr 20;292(5516):468-72
Science (New York, N.Y.) 2001 Apr 20;292(5516):468-72
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.
Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ
Nature 1999 May 20;399(6733):271-5
Nature 1999 May 20;399(6733):271-5
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
Wang GL, Jiang BH, Rue EA, Semenza GL
Proceedings of the National Academy of Sciences of the United States of America 1995 Jun 6;92(12):5510-4
Proceedings of the National Academy of Sciences of the United States of America 1995 Jun 6;92(12):5510-4
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
