FAB5317P

antibody from R&D Systems

Targeting: NOTCH1 TAN1

Flow cytometry (Recommended by provider)

Antibody Data

Product number

FAB5317P

Provider

R&D Systems

Product name

Anti-Human Notch-1 PE-conjugated Monoclonal Antibody (Clone 527425)

Antibody type

Monoclonal

Antigen

Mouse myeloma cell line NS0-derived recombinant human Notch-1, aa 19-526

Description

Protein A or G purified from hybridoma culture supernatant

Reactivity

Human

Host

Mouse

Conjugate

Yellow dye

Antigen sequence

P46531


Isotype

IgG

Vial size

100 Tests

References

Submitted references

Activation of Notch-1 in oral epithelial cells by P. gingivalis triggers the expression of the antimicrobial protein PLA₂-IIA.

Al-Attar A, Alimova Y, Kirakodu S, Kozal A, Novak MJ, Stromberg AJ, Orraca L, Gonzalez-Martinez J, Martinez M, Ebersole JL, Gonzalez OA
Mucosal immunology 2018 Jul;11(4):1047-1059

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Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis.

Piggott K, Deng J, Warrington K, Younge B, Kubo JT, Desai M, Goronzy JJ, Weyand CM
Circulation 2011 Jan 25;123(3):309-18