Antibody data
- Antibody Data
- Antigen structure
- References [20]
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- Validations
- Flow cytometry [3]
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- Product number
- NBP2-24777 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rabbit Polyclonal TLR7 Antibody
- Antibody type
- Polyclonal
Submitted references Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE.
Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.
Analysis of the membrane proteome of ciprofloxacin-resistant macrophages by stable isotope labeling with amino acids in cell culture (SILAC).
The MyD88 pathway in plasmacytoid and CD4+ dendritic cells primarily triggers type I IFN production against measles virus in a mouse infection model.
Identification of lineage relationships and novel markers of blood and skin human dendritic cells.
Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses.
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific.
Toll-like receptor 7-triggered immune response in the lung mediates acute and long-lasting suppression of experimental asthma.
Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block.
Toll-like receptors 3, 4, and 7 are expressed in the enteric nervous system and dorsal root ganglia.
Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract.
Antitumor effects of imidazoquinolines in urothelial cell carcinoma of the bladder.
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.
Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice.
Toll-like receptor-7 modulates immune complex glomerulonephritis.
Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad.
Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad.
Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line.
TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production.
TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production.
Saito K, Kukita K, Kutomi G, Okuya K, Asanuma H, Tabeya T, Naishiro Y, Yamamoto M, Takahashi H, Torigoe T, Nakai A, Shinomura Y, Hirata K, Sato N, Tamura Y
European journal of immunology 2015 Jul;45(7):2028-41
European journal of immunology 2015 Jul;45(7):2028-41
Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.
Abdi J, Mutis T, Garssen J, Redegeld F
PloS one 2013;8(4):e60671
PloS one 2013;8(4):e60671
Analysis of the membrane proteome of ciprofloxacin-resistant macrophages by stable isotope labeling with amino acids in cell culture (SILAC).
Caceres NE, Aerts M, Marquez B, Mingeot-Leclercq MP, Tulkens PM, Devreese B, Van Bambeke F
PloS one 2013;8(3):e58285
PloS one 2013;8(3):e58285
The MyD88 pathway in plasmacytoid and CD4+ dendritic cells primarily triggers type I IFN production against measles virus in a mouse infection model.
Takaki H, Takeda M, Tahara M, Shingai M, Oshiumi H, Matsumoto M, Seya T
Journal of immunology (Baltimore, Md. : 1950) 2013 Nov 1;191(9):4740-7
Journal of immunology (Baltimore, Md. : 1950) 2013 Nov 1;191(9):4740-7
Identification of lineage relationships and novel markers of blood and skin human dendritic cells.
Harman AN, Bye CR, Nasr N, Sandgren KJ, Kim M, Mercier SK, Botting RA, Lewin SR, Cunningham AL, Cameron PU
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):66-79
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):66-79
Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses.
Krejbich-Trotot P, Denizot M, Hoarau JJ, Jaffar-Bandjee MC, Das T, Gasque P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 Jan;25(1):314-25
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 Jan;25(1):314-25
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific.
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, Bucchi A, Krux F, Dittmer U, Yang D, Roggendorf M, Gerken G, Lu M, Schlaak JF
Immunology 2010 Mar;129(3):363-74
Immunology 2010 Mar;129(3):363-74
Toll-like receptor 7-triggered immune response in the lung mediates acute and long-lasting suppression of experimental asthma.
Xirakia C, Koltsida O, Stavropoulos A, Thanassopoulou A, Aidinis V, Sideras P, Andreakos E
American journal of respiratory and critical care medicine 2010 Jun 1;181(11):1207-16
American journal of respiratory and critical care medicine 2010 Jun 1;181(11):1207-16
Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block.
Clancy RM, Alvarez D, Komissarova E, Barrat FJ, Swartz J, Buyon JP
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 15;184(4):2148-55
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 15;184(4):2148-55
Toll-like receptors 3, 4, and 7 are expressed in the enteric nervous system and dorsal root ganglia.
Barajon I, Serrao G, Arnaboldi F, Opizzi E, Ripamonti G, Balsari A, Rumio C
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 Nov;57(11):1013-23
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 Nov;57(11):1013-23
Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract.
Palladino MA, Johnson TA, Gupta R, Chapman JL, Ojha P
Biology of reproduction 2007 Jun;76(6):958-64
Biology of reproduction 2007 Jun;76(6):958-64
Antitumor effects of imidazoquinolines in urothelial cell carcinoma of the bladder.
Smith EB, Schwartz M, Kawamoto H, You X, Hwang D, Liu H, Scherr DS
The Journal of urology 2007 Jun;177(6):2347-51
The Journal of urology 2007 Jun;177(6):2347-51
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.
Brinkmann MM, Spooner E, Hoebe K, Beutler B, Ploegh HL, Kim YM
The Journal of cell biology 2007 Apr 23;177(2):265-75
The Journal of cell biology 2007 Apr 23;177(2):265-75
Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice.
Patole PS, Pawar RD, Lech M, Zecher D, Schmidt H, Segerer S, Ellwart A, Henger A, Kretzler M, Anders HJ
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006 Nov;21(11):3062-73
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006 Nov;21(11):3062-73
Toll-like receptor-7 modulates immune complex glomerulonephritis.
Pawar RD, Patole PS, Zecher D, Segerer S, Kretzler M, Schlöndorff D, Anders HJ
Journal of the American Society of Nephrology : JASN 2006 Jan;17(1):141-9
Journal of the American Society of Nephrology : JASN 2006 Jan;17(1):141-9
Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad.
François S, El Benna J, Dang PM, Pedruzzi E, Gougerot-Pocidalo MA, Elbim C
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3633-42
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3633-42
Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad.
François S, El Benna J, Dang PM, Pedruzzi E, Gougerot-Pocidalo MA, Elbim C
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3633-42
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3633-42
Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line.
Srivastava MD, Srivastava BI
Leukemia research 2005 Jul;29(7):813-20
Leukemia research 2005 Jul;29(7):813-20
TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production.
Hart OM, Athie-Morales V, O'Connor GM, Gardiner CM
Journal of immunology (Baltimore, Md. : 1950) 2005 Aug 1;175(3):1636-42
Journal of immunology (Baltimore, Md. : 1950) 2005 Aug 1;175(3):1636-42
TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production.
Hart OM, Athie-Morales V, O'Connor GM, Gardiner CM
Journal of immunology (Baltimore, Md. : 1950) 2005 Aug 1;175(3):1636-42
Journal of immunology (Baltimore, Md. : 1950) 2005 Aug 1;175(3):1636-42
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR7 Antibody [FITC] [NBP2-24777] - Intracellular staining by analysis of TLR7 in human monocytes using this antibody at 0.5 ug/10^6 cells. Shaded histogram represents cells alone, green represents rabbit IgG isotype control, red represents anti-TLR7 antibody.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR7 Antibody [FITC] [NBP2-24777] - Intracellular flow analysis of TLR7 in TLR7/HEK 293 cells using NBP2-24777 at 1 ug/10^6 cells. Green represents Vector/HEK 293 cells; red represents TLR7/HEK 293 .
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR7 Antibody [FITC] [NBP2-24777] - Analysis of TLR7 in Balb/c mouse splenocytes using this antibody. Green represents rabbit IgG isotype control ; red represents anti-TLR7 antibody.