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- Antigen structure
- References [2]
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- Validations
- Western blot [2]
- Flow cytometry [1]
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- Product number
- AM20375PU-N - Provider product page
- Provider
- Acris Antibodies GmbH
- Proper citation
- Acris Antibodies GmbH Cat#AM20375PU-N, RRID:AB_10755338
- Product name
- anti TLR7 (562-839)
- Antibody type
- Monoclonal
- Antigen
- TLR7 recombinant protein (amino acids 562-839).
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- IMG4G6
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
Submitted references Distinct autoantibody profiles in systemic lupus erythematosus patients are selectively associated with TLR7 and TLR9 upregulation.
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Chauhan SK, Singh VV, Rai R, Rai M, Rai G
Journal of clinical immunology 2013 Jul;33(5):954-64
Journal of clinical immunology 2013 Jul;33(5):954-64
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Lehmann SM, Krüger C, Park B, Derkow K, Rosenberger K, Baumgart J, Trimbuch T, Eom G, Hinz M, Kaul D, Habbel P, Kälin R, Franzoni E, Rybak A, Nguyen D, Veh R, Ninnemann O, Peters O, Nitsch R, Heppner FL, Golenbock D, Schott E, Ploegh HL, Wulczyn FG, Lehnardt S
Nature neuroscience 2012 Jun;15(6):827-35
Nature neuroscience 2012 Jun;15(6):827-35
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Supportive validation
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Western blot analysis of human TLR7 antibody in Ramos and transfected 293T lysate using TLR7 monoclonal antibody at 10 µg/ml.
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- TLR7 antibodies tested at 2 µg/ml on recombinant partial hTLR7 protein (amino acids 562-839). SP7200P and AP22295PU-N immunogen sequences are not present in recombinant protein; SP7199P is not recommended for use in western blot.
Supportive validation
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Flow cytometric analysis of TLR7 in human monocytes using 2 µg of TLR7 monoclonal antibody (red) and 2 µg of mouse IgG1 isotype control antibody. TLR intracellular flow kit was used for this test, and an anti-mouse IgG PE conjugated secondary antibody.
