Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations [0]
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- Product number
- MAB419-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse IL-12 p70 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse IL-12 in ELISAs and Western blots. Detects an epitope in the p35 subunit. In sandwich ELISAs, does not cross-react with recombinant mouse IL-12 p40.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 48110
- Vial size
- 100 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Therapeutic reversal of food allergen sensitivity by mature retinoic acid-differentiated dendritic cell induction of LAG3+CD49b-Foxp3- regulatory T cells.
Eriobotrya japonica Water Extract Characterization: An Inducer of Interferon-Gamma Production Mainly by the JAK-STAT Pathway.
Dichloroacetate modulates cytokines toward T helper 1 function via induction of the interleukin-12-interferon-γ pathway.
Response patterns of cytokines/chemokines in two murine strains after irradiation.
The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function.
NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity.
Expression of bioactive single-chain murine IL-12 in transgenic plants.
Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator.
Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile.
Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages.
Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis.
Sequential ELISA to profile multiple cytokines from small volumes.
Nonlymphoid peritoneal cells suppress the T cell response to Mls.
17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells.
Dawicki W, Li C, Town J, Zhang X, Gordon JR
The Journal of allergy and clinical immunology 2017 May;139(5):1608-1620.e3
The Journal of allergy and clinical immunology 2017 May;139(5):1608-1620.e3
Eriobotrya japonica Water Extract Characterization: An Inducer of Interferon-Gamma Production Mainly by the JAK-STAT Pathway.
Matalka KZ, Abdulridha NA, Badr MM, Mansoor K, Qinna NA, Qadan F
Molecules (Basel, Switzerland) 2016 Jun 2;21(6)
Molecules (Basel, Switzerland) 2016 Jun 2;21(6)
Dichloroacetate modulates cytokines toward T helper 1 function via induction of the interleukin-12-interferon-γ pathway.
Badr MM, Qinna NA, Qadan F, Matalka KZ
OncoTargets and therapy 2014;7:193-201
OncoTargets and therapy 2014;7:193-201
Response patterns of cytokines/chemokines in two murine strains after irradiation.
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, Salzman P, Wang W, Liu C, Vidyasagar S, Zhang L, Ju S, Okunieff P, Zhang L
Cytokine 2012 May;58(2):169-77
Cytokine 2012 May;58(2):169-77
The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function.
Jin W, Qi S, Luo H
BMC immunology 2011 Dec 19;12:68
BMC immunology 2011 Dec 19;12:68
NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity.
Divangahi M, Mostowy S, Coulombe F, Kozak R, Guillot L, Veyrier F, Kobayashi KS, Flavell RA, Gros P, Behr MA
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 15;181(10):7157-65
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 15;181(10):7157-65
Expression of bioactive single-chain murine IL-12 in transgenic plants.
Liu J, Dolan MC, Reidy M, Cramer CL
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2008 Jun;28(6):381-92
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2008 Jun;28(6):381-92
Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator.
Chiang YM, Chang CL, Chang SL, Yang WC, Shyur LF
Journal of ethnopharmacology 2007 Apr 4;110(3):532-8
Journal of ethnopharmacology 2007 Apr 4;110(3):532-8
Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile.
Wen H, Hogaboam CM, Gauldie J, Kunkel SL
The American journal of pathology 2006 Jun;168(6):1940-50
The American journal of pathology 2006 Jun;168(6):1940-50
Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages.
An HJ, Jeong HJ, Um JY, Kim HM, Hong SH
Journal of ethnopharmacology 2006 Jul 19;106(3):418-24
Journal of ethnopharmacology 2006 Jul 19;106(3):418-24
Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis.
Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, Ito T, Matsukawa A
Journal of immunology (Baltimore, Md. : 1950) 2006 Dec 15;177(12):8650-7
Journal of immunology (Baltimore, Md. : 1950) 2006 Dec 15;177(12):8650-7
Sequential ELISA to profile multiple cytokines from small volumes.
Osuchowski MF, Siddiqui J, Copeland S, Remick DG
Journal of immunological methods 2005 Jul;302(1-2):172-81
Journal of immunological methods 2005 Jul;302(1-2):172-81
Nonlymphoid peritoneal cells suppress the T cell response to Mls.
Rosini L, Matlack R, Taylor J, Howell KF, Yeh K, Pennello A, Riggs JE
Immunobiology 2004;209(8):575-84
Immunobiology 2004;209(8):575-84
17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells.
Bengtsson AK, Ryan EJ, Giordano D, Magaletti DM, Clark EA
Blood 2004 Sep 1;104(5):1404-10
Blood 2004 Sep 1;104(5):1404-10
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