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Western blot
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- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- ABIN263948 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Heat Shock Protein 60 (HSP60) antibody
- Antibody type
- Monoclonal
- Antigen
- Heat Shock Protein 60 (HSP60)
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Guinea Pig, Hamster, Porcine, Rabbit, Simian, Yeast
- Host
- Mouse
- Antigen sequence
Human Hsp60 produced through recomb
inant DNA methods in E. coli- Isotype
- IgG
- Vial size
- 0.2 mg
- Concentration
- 1.0 mg/mL
Submitted references Regulation of IGF-I receptor signaling in diabetic cardiac muscle: dysregulation of cytosolic and mitochondria HSP60.
On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60.
HSP60, Bax, apoptosis and the heart.
Interaction of antibodies against cytomegalovirus with heat-shock protein 60 in pathogenesis of atherosclerosis.
Molecular chaperones in the cytosol: from nascent chain to folded protein.
Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration.
Chlamydial heat shock proteins and disease pathology: new paradigms for old problems?
The Hsp70 and Hsp60 chaperone machines.
Molecular chaperones in cellular protein folding.
Experimental autoimmune encephalomyelitis. Qualitative and semiquantitative differences in heat shock protein 60 expression in the central nervous system.
Primary structure of a human mitochondrial protein homologous to the bacterial and plant chaperonins and to the 65-kilodalton mycobacterial antigen.
Lai HC, Liu TJ, Ting CT, Yang JY, Huang L, Wallace D, Kaiser P, Wang PH
American journal of physiology. Endocrinology and metabolism 2007 Jan;292(1):E292-7
American journal of physiology. Endocrinology and metabolism 2007 Jan;292(1):E292-7
On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60.
Deocaris CC, Kaul SC, Wadhwa R
Cell stress & chaperones 2006 Summer;11(2):116-28
Cell stress & chaperones 2006 Summer;11(2):116-28
HSP60, Bax, apoptosis and the heart.
Gupta S, Knowlton AA
Journal of cellular and molecular medicine 2005 Jan-Mar;9(1):51-8
Journal of cellular and molecular medicine 2005 Jan-Mar;9(1):51-8
Interaction of antibodies against cytomegalovirus with heat-shock protein 60 in pathogenesis of atherosclerosis.
Bason C, Corrocher R, Lunardi C, Puccetti P, Olivieri O, Girelli D, Navone R, Beri R, Millo E, Margonato A, Martinelli N, Puccetti A
Lancet 2003 Dec 13;362(9400):1971-7
Lancet 2003 Dec 13;362(9400):1971-7
Molecular chaperones in the cytosol: from nascent chain to folded protein.
Hartl FU, Hayer-Hartl M
Science (New York, N.Y.) 2002 Mar 8;295(5561):1852-8
Science (New York, N.Y.) 2002 Mar 8;295(5561):1852-8
Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration.
Itoh H, Komatsuda A, Ohtani H, Wakui H, Imai H, Sawada K, Otaka M, Ogura M, Suzuki A, Hamada F
European journal of biochemistry / FEBS 2002 Dec;269(23):5931-8
European journal of biochemistry / FEBS 2002 Dec;269(23):5931-8
Chlamydial heat shock proteins and disease pathology: new paradigms for old problems?
LaVerda D, Kalayoglu MV, Byrne GI
Infectious diseases in obstetrics and gynecology 1999;7(1-2):64-71
Infectious diseases in obstetrics and gynecology 1999;7(1-2):64-71
The Hsp70 and Hsp60 chaperone machines.
Bukau B, Horwich AL
Cell 1998 Feb 6;92(3):351-66
Cell 1998 Feb 6;92(3):351-66
Molecular chaperones in cellular protein folding.
Hartl FU
Nature 1996 Jun 13;381(6583):571-9
Nature 1996 Jun 13;381(6583):571-9
Experimental autoimmune encephalomyelitis. Qualitative and semiquantitative differences in heat shock protein 60 expression in the central nervous system.
Gao YL, Brosnan CF, Raine CS
Journal of immunology (Baltimore, Md. : 1950) 1995 Apr 1;154(7):3548-56
Journal of immunology (Baltimore, Md. : 1950) 1995 Apr 1;154(7):3548-56
Primary structure of a human mitochondrial protein homologous to the bacterial and plant chaperonins and to the 65-kilodalton mycobacterial antigen.
Jindal S, Dudani AK, Singh B, Harley CB, Gupta RS
Molecular and cellular biology 1989 May;9(5):2279-83
Molecular and cellular biology 1989 May;9(5):2279-83
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Gels were loaded with 1, 2.5, 5.0 and 7.5 μg/lane of HeLa and Raw204.4 cell lysates. 0.2 μg/ml primary antibody was used, blocking buffer (Blotto; 5% dry milk powder in TBST). R1253HRP anti Mouse IgG (H+L) secondary antibody at 1/20.000 dilution was used.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of Listeria infected mice spleens 6 days after infection with L-monocytogenes using AM03145PU (Clone LK2).
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Hsp60 visualized using AM03145PU (Clone LK2), tested on Human colon cancer cells.
