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- Antibody Data
- Antigen structure
- References [6]
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- Product number
- MAB1029 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse Cathepsin D Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects both the pro and active forms of mouse Cathepsin D in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human Cathepsin D or recombinant mouse Cathepsin E is observed.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
P18242- Isotype
- IgG
- Antibody clone number
- 204712
- Vial size
- 500 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Lack of Cathepsin D in the Renal Proximal Tubular Cells Resulted in Increased Sensitivity against Renal Ischemia/Reperfusion Injury.
Activation of autophagy rescues synaptic and cognitive deficits in fragile X mice.
GDE2 is essential for neuronal survival in the postnatal mammalian spinal cord.
Cleavage of Histone 3 by Cathepsin D in the involuting mammary gland.
The iron export protein ferroportin 1 is differentially expressed in mouse macrophage populations and is present in the mycobacterial-containing phagosome.
Securinine, a GABAA receptor antagonist, enhances macrophage clearance of phase II C. burnetii: comparison with TLR agonists.
Suzuki C, Tanida I, Ohmuraya M, Oliva Trejo JA, Kakuta S, Sunabori T, Uchiyama Y
International journal of molecular sciences 2019 Apr 5;20(7)
International journal of molecular sciences 2019 Apr 5;20(7)
Activation of autophagy rescues synaptic and cognitive deficits in fragile X mice.
Yan J, Porch MW, Court-Vazquez B, Bennett MVL, Zukin RS
Proceedings of the National Academy of Sciences of the United States of America 2018 Oct 9;115(41):E9707-E9716
Proceedings of the National Academy of Sciences of the United States of America 2018 Oct 9;115(41):E9707-E9716
GDE2 is essential for neuronal survival in the postnatal mammalian spinal cord.
Cave C, Park S, Rodriguez M, Nakamura M, Hoke A, Pletnikov M, Sockanathan S
Molecular neurodegeneration 2017 Jan 19;12(1):8
Molecular neurodegeneration 2017 Jan 19;12(1):8
Cleavage of Histone 3 by Cathepsin D in the involuting mammary gland.
Khalkhali-Ellis Z, Goossens W, Margaryan NV, Hendrix MJ
PloS one 2014;9(7):e103230
PloS one 2014;9(7):e103230
The iron export protein ferroportin 1 is differentially expressed in mouse macrophage populations and is present in the mycobacterial-containing phagosome.
Van Zandt KE, Sow FB, Florence WC, Zwilling BS, Satoskar AR, Schlesinger LS, Lafuse WP
Journal of leukocyte biology 2008 Sep;84(3):689-700
Journal of leukocyte biology 2008 Sep;84(3):689-700
Securinine, a GABAA receptor antagonist, enhances macrophage clearance of phase II C. burnetii: comparison with TLR agonists.
Lubick K, Radke M, Jutila M
Journal of leukocyte biology 2007 Nov;82(5):1062-9
Journal of leukocyte biology 2007 Nov;82(5):1062-9
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