ABIN183608

antibody from antibodies-online

Targeting: FLI1 EWSR2, SIC-1

Western blot (Data presented on provider website)

Antibody Data

Product number

ABIN183608

Provider

antibodies-online

Product name

anti-Friend Leukemia Virus Integration 1 (FLI1) (N-Term) antibody

Antibody type

Polyclonal

Antigen

The immunogen for anti-FLI1 antibody: synthetic peptide directed towards the N terminal of human FLI1

Description

Protein A purified

Reactivity

Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Xenopus, Zebrafish

Host

Rabbit

Antigen sequence

MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMT
ASGSP DYGQPHKINP


Epitope

N-Term

Vial size

100 μg

Concentration

1mg/mL

Storage

-20°C

Handling

Avoid repeated freeze-thaw cycles.

References

Submitted references

Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1.

Bujor AM, Haines P, Padilla C, Christmann RB, Junie M, Sampaio-Barros PD, Lafyatis R, Trojanowska M
International journal of molecular medicine 2012 Dec;30(6):1473-80

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FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family.

van den Akker E, Ano S, Shih HM, Wang LC, Pironin M, Palvimo JJ, Kotaja N, Kirsh O, Dejean A, Ghysdael J
The Journal of biological chemistry 2005 Nov 11;280(45):38035-46

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The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity.

van den Akker E, van Dijk TB, Schmidt U, Felida L, Beug H, Löwenberg B, von Lindern M
Biological chemistry 2004 May;385(5):409-13