BAF633

antibody from R&D Systems

Targeting: TNFRSF10D CD264, DcR2, TRAILR4, TRUNDD

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

BAF633

Provider

R&D Systems

Product name

Human TRAILR4/TNFRSF10D Biotinylated Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects human TRAIL R4/TNFRSF10D in ELISAs and Western blots. In sandwich immunoassays, less than 3.5% cross-reactivity with recombinant human (rh) TRAIL R3 is observed and less than 0.5% cross-reactivity with rhTRAIL R1, rhTRAIL R2, rhTRAIL, rhTNF-alpha , and rhTNF-beta is observed.

Reactivity

Human

Host

Goat

Conjugate

Biotin

Antigen sequence

Q9UBN6


Isotype

IgG

Vial size

50 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Rapid and profound potentiation of Apo2L/TRAIL-mediated cytotoxicity and apoptosis in thoracic cancer cells by the histone deacetylase inhibitor Trichostatin A: the essential role of the mitochondria-mediated caspase activation cascade.

Reddy RM, Yeow WS, Chua A, Nguyen DM, Baras A, Ziauddin MF, Shamimi-Noori SM, Maxhimer JB, Schrump DS, Nguyen DM
Apoptosis : an international journal on programmed cell death 2007 Jan;12(1):55-71

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Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin.

Tsai WS, Yeow WS, Chua A, Reddy RM, Nguyen DM, Schrump DS, Nguyen DM
Molecular cancer therapeutics 2006 Dec;5(12):2977-90