Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB633G - Provider product page
- Provider
- R&D Systems
- Product name
- Human TRAILR4/TNFRSF10D Alexa Fluor® 488-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human TRAIL R4/TNFRSF10D in ELISAs and Western blots. In sandwich immunoassays, less than 5% cross-reactivity with recombinant human (rh) TRAIL R1, rhTRAIL R2, rhTRAIL R3, rhTRAIL, rhTNF-alpha , and rhTNF-beta is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Green dye
- Antigen sequence
Q9UBN6
- Isotype
- IgG
- Antibody clone number
- 104918
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells.
Shlyakhtina Y, Pavet V, Gronemeyer H
Cell death & disease 2017 Aug 31;8(8):e3025
Cell death & disease 2017 Aug 31;8(8):e3025
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- Detection of TRAIL R4/TNFRSF10D in Human Whole Blood Granulocytes by Flow Cytometry. Human whole blood granulocytes were stained with Mouse Anti-Human TRAIL R4/TNFRSF10D Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # FAB633G, filled histogram) or isotype control antibody (Catalog # IC002G, open histogram). View our protocol for Staining Membrane-associated Proteins.