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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [31]
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- Immunohistochemistry [4]
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- Product number
- 10529-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10529-1-AP, RRID:AB_2081122
- Product name
- Chromogranin A antibody
- Antibody type
- Polyclonal
- Description
- Chromogranin A antibody (Cat. #10529-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Geometrically Constrained Growth Factor Concentration Favors Enrichment of Goblet Cells and Mucus Formation.
Microbiota-driven tryptophan metabolism and AhR triggered intestinal stem cell differentiation: mechanisms of huangqin decoction in ulcerative colitis repair.
BLOC1S1 variants cause lysosomal and autophagic defects resulting in a hypomyelinating leukodystrophy with epileptic encephalopathy.
Study on the effects of the atractylodes macrocephala koidz-raphanus sativus l herb pair in alleviating senile constipation via the gut microbiota-SCFAs-5-HT axis.
Molecular and immune characteristics of neuroendocrine bladder carcinoma - Implications for diagnosis, prognosis, and therapy: A review.
Comparison of the Construction Methods of Parathyroid Organoids and Functional Influence of Calcium on Organoids.
CHD3 and CHD4 coordinate gene expression programs to maintain β-cell function and identity in vivo.
A novel scheme for non-invasive drug delivery with a magnetically controlled drug delivering capsule endoscope.
BLOC1S1 variants cause lysosomal and autophagic defects resulting in a hypomyelinating leukodystrophy with epileptic encephalopathy.
Piezo knockdown reduces 5‑hydroxytryptamine release from enterochromaffin cells and exacerbates intestinal dyskinesia in mice with functional constipation.
Enteric nervous system-derived VIP restrains differentiation of LGR5(+) stem cells toward the secretory lineage impeding type 2 immune programs.
Diet-dependent modulation of energy balance by CB1 signaling in peripheral sensory neurons.
Melatonin via MTNR1B regulates METTL3 to protect ileum cell differentiation.
Histone demethylase PHF8 promotes prostate cancer metastasis via the E2F1-SNAI1 axis.
PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility.
Endoplasmic reticulum stress impedes regulated secretion by governing key exocytotic and granulogenic molecular switches.
A hydrolyzed casein diet promotes Ngn3 controlling enteroendocrine cell differentiation to increase gastrointestinal motility in mice.
1,25-Dihydroxyvitamin D Enhances the Regenerative Function of Lgr5(+) Intestinal Stem Cells In Vitro and In Vivo.
Role of Forkhead Box P3 in IFNγ-Mediated PD-L1 Expression and Bladder Cancer Epithelial-to-Mesenchymal Transition.
OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion.
Depiction of neuroendocrine features associated with immunotherapy response using a novel one-class predictor in lung adenocarcinoma.
The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo.
Budget-Friendly Generation, Biochemical Analyses, and Lentiviral Transduction of Patient-Derived Colon Organoids.
Colonic L-cell impairment in aged subjects with type 2 diabetes leads to diminished GLP-1 production.
Profile of chimeric RNAs and TMPRSS2-ERG e2e4 isoform in neuroendocrine prostate cancer.
Shouhui Tongbian Capsule ameliorates constipation via gut microbiota-5-HT-intestinal motility axis.
A novel hypoxia-driven gene signature that can predict the prognosis of hepatocellular carcinoma.
The Protective Effects of Apigenin Against Radiation-Induced Intestinal Injury.
Glycerate from intestinal fructose metabolism induces islet cell damage and glucose intolerance.
Generation and characterization of CRISPR/Cas9-mediated MEN1 knockout BON1 cells: a human pancreatic neuroendocrine cell line.
Protein O-GlcNAc Modification Links Dietary and Gut Microbial Cues to the Differentiation of Enteroendocrine L Cells.
Villegas-Novoa C, Wang Y, Wang H, Jan I, Sims CE, Allbritton NL
ACS biomaterials science & engineering 2026 May 11;12(5):2700-2713
ACS biomaterials science & engineering 2026 May 11;12(5):2700-2713
Microbiota-driven tryptophan metabolism and AhR triggered intestinal stem cell differentiation: mechanisms of huangqin decoction in ulcerative colitis repair.
Li R, Liao X, Fu X, Li X, Liao X, Cen S, Zeng J, Huang L, Chi H, Zou Y
Chinese medicine 2026 Jan 13;21(1):33
Chinese medicine 2026 Jan 13;21(1):33
BLOC1S1 variants cause lysosomal and autophagic defects resulting in a hypomyelinating leukodystrophy with epileptic encephalopathy.
De Pace R, Dominguez Gonzalez CA, Williamson CD, Helman G, Sanderson LE, Disanza B, Hsiao-Sánchez N, Pizzino A, Muirhead K, Bonkowsky JL, Taft RJ, Sannaa NA, Dias P, Quintas AS, Mutlu MB, Bas H, Oztürk H, Mojarrad M, Alerasool M, Sheikhani S, Jabbar HK, Issa AH, Houlden H, Zonic E, Barakat TS, Tripolski K, Romito A, Teferedegn E, Vossough A, Whitehead MT, Bhoj E, Ahrens-Nicklas RC, Simons C, Wolvetang E, van Ham TJ, Bertoli-Avella AM, Maroofian R, Bonifacino JS, Vanderver A
American journal of human genetics 2026 Apr 2;113(4):736-753
American journal of human genetics 2026 Apr 2;113(4):736-753
Study on the effects of the atractylodes macrocephala koidz-raphanus sativus l herb pair in alleviating senile constipation via the gut microbiota-SCFAs-5-HT axis.
Gao F, Su J, Li J, Gan C, Jin X, Zhou H, Liu X, Yu J, Yan M, Chen S, Lv G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156977
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156977
Molecular and immune characteristics of neuroendocrine bladder carcinoma - Implications for diagnosis, prognosis, and therapy: A review.
Zhang T, Zhang X, Qian L, Hu C, Li J
Biomolecules & biomedicine 2025 Oct 9;26(5):711-719
Biomolecules & biomedicine 2025 Oct 9;26(5):711-719
Comparison of the Construction Methods of Parathyroid Organoids and Functional Influence of Calcium on Organoids.
Xu C, Liu H, She J, Xu T, Zhou Y, Yan X, Li T, Dai B
Artificial organs 2025 Nov;49(11):1623-1632
Artificial organs 2025 Nov;49(11):1623-1632
CHD3 and CHD4 coordinate gene expression programs to maintain β-cell function and identity in vivo.
Kanojia S, Sharma AD, George RM, Taylor AG, Wu W, Dickerson MT, Peachee SJ, Dadi PK, Kacher A, Devaguptapu H, Davidson RK, Nag S, Huter K, Osmulski M, Sandoval K, Jacobson DA, Spaeth JM
Research square 2025 Nov 7;
Research square 2025 Nov 7;
A novel scheme for non-invasive drug delivery with a magnetically controlled drug delivering capsule endoscope.
Wang W, Zhang K, Ming F, Chen B, Zhang H, Wang Z, Jiang X, Zhang H, Shang G, Bao Y, Peng H, Liu S, Ling X, Li W, Zhu H, Zhang Y, Cai S, Ding Z, Lin R
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113591
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113591
BLOC1S1 variants cause lysosomal and autophagic defects resulting in a hypomyelinating leukodystrophy with epileptic encephalopathy.
De Pace R, Gonzalez CD, Williamson CD, Helman G, Sanderson LE, Disanza B, Hsiao-Sánchez N, Pizzino A, Muirhead K, Bonkowsky JL, Taft RJ, Sannaa NA, Dias P, Quintas AS, Mutlu MB, Bas H, Oztürk H, Mojarrad M, Alerasool M, Sheikhani S, Jabbar HK, Issa AH, Houlden H, Zonic E, Barakat TS, Tripolski K, Romito A, Teferedegn E, Vossough A, Whitehead MT, Bhoj E, Ahrens-Nicklas RC, Simons C, Wolvetang E, van Ham TJ, Bertoli-Avella AM, Maroofian R, Bonifacino JS, Vanderver A
medRxiv : the preprint server for health sciences 2025 Jul 17;
medRxiv : the preprint server for health sciences 2025 Jul 17;
Piezo knockdown reduces 5‑hydroxytryptamine release from enterochromaffin cells and exacerbates intestinal dyskinesia in mice with functional constipation.
Yan X, Ma P, Wang W, Zeng W, Li Y, Hou Y, Ye J, Zheng Q, Zhang W, Yao J, Li Y
International journal of molecular medicine 2025 Dec;56(6)
International journal of molecular medicine 2025 Dec;56(6)
Enteric nervous system-derived VIP restrains differentiation of LGR5(+) stem cells toward the secretory lineage impeding type 2 immune programs.
Jakob MO, Sterczyk N, Boulekou S, Forster PM, Barleben L, Alzain N, Jarick KJ, Pirzgalska RM, Raposo B, Hansson K, Nyström EEL, Gondrand A, González-Acera M, Leclère PS, Lapson MS, Poggenseier S, Deshpande D, Velleman L, Breiderhoff T, Brunkhorst MF, Schüle AM, Guerra GM, Durek P, Mashreghi MF, Kühl AA, Chu C, Schneider C, Weidinger C, Siegmund B, Nordmann TM, Voehringer D, Patankar JV, Becker C, Birchenough GMH, Veiga-Fernandes H, Ronchi F, Kolesnichenko M, Diefenbach A, Klose CSN
Nature immunology 2025 Dec;26(12):2227-2243
Nature immunology 2025 Dec;26(12):2227-2243
Diet-dependent modulation of energy balance by CB1 signaling in peripheral sensory neurons.
Linden B, Herz H, Jarrah M, Tasabehji D, Saleh S, Fraer A, Clark P, Ye Y, Chu Y, Al-Khalil Z, Morgan DA, Zhu Z, Castorena CM, Zingman L, Rahmouni K, Mokadem M
iScience 2025 Aug 15;28(8):113124
iScience 2025 Aug 15;28(8):113124
Melatonin via MTNR1B regulates METTL3 to protect ileum cell differentiation.
Li Y, Sun Y, Chen Y, Dong Y
Inflammation 2025 Apr;48(2):935-949
Inflammation 2025 Apr;48(2):935-949
Histone demethylase PHF8 promotes prostate cancer metastasis via the E2F1-SNAI1 axis.
Wang Z, Tang P, Xiao H, Peng S, Chen J, Wang Y, Xu J, Yan Q, Zhang J, Deng J, Ma Q, Zhu H, Luo W, Zhang D, Wang L, Qin J, Lan W, Jiang J, Liu Q
The Journal of pathology 2024 Sep;264(1):68-79
The Journal of pathology 2024 Sep;264(1):68-79
PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility.
Jing N, Du X, Liang Y, Tao Z, Bao S, Xiao H, Dong B, Gao WQ, Fang YX
Journal of experimental & clinical cancer research : CR 2024 May 15;43(1):144
Journal of experimental & clinical cancer research : CR 2024 May 15;43(1):144
Endoplasmic reticulum stress impedes regulated secretion by governing key exocytotic and granulogenic molecular switches.
Mukherjee M, Mukherjee C, Ghosh V, Jain A, Sadhukhan S, Dagar S, Sahu BS
Journal of cell science 2024 Mar 15;137(6)
Journal of cell science 2024 Mar 15;137(6)
A hydrolyzed casein diet promotes Ngn3 controlling enteroendocrine cell differentiation to increase gastrointestinal motility in mice.
Liu S, Zhu H, Ren Y, Fan W, Wu H, Wu H, Huang Z, Zhu W
Food & function 2024 Feb 5;15(3):1237-1249
Food & function 2024 Feb 5;15(3):1237-1249
1,25-Dihydroxyvitamin D Enhances the Regenerative Function of Lgr5(+) Intestinal Stem Cells In Vitro and In Vivo.
Shaikh NA, Liu C, Yin Y, Baylink DJ, Tang X
Cells 2024 Aug 31;13(17)
Cells 2024 Aug 31;13(17)
Role of Forkhead Box P3 in IFNγ-Mediated PD-L1 Expression and Bladder Cancer Epithelial-to-Mesenchymal Transition.
Zhang H, Ly A, Chou E, Wang L, Zhang P, Prado K, Gu Y, Pellegrini M, Chin AI
Cancer research communications 2024 Aug 1;4(8):2228-2241
Cancer research communications 2024 Aug 1;4(8):2228-2241
OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion.
Panagiotou S, Tan KW, Nguyen PM, Müller A, Oqua AI, Tomas A, Wendt A, Eliasson L, Tengholm A, Solimena M, Idevall-Hagren O
Cell reports 2024 Apr 23;43(4):113992
Cell reports 2024 Apr 23;43(4):113992
Depiction of neuroendocrine features associated with immunotherapy response using a novel one-class predictor in lung adenocarcinoma.
Liu H, Han Y, Liu Z, Gao L, Yi T, Yu Y, Wang Y, Qu P, Xiang L, Li Y
Discover oncology 2023 May 18;14(1):71
Discover oncology 2023 May 18;14(1):71
The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo.
Davidson RK, Kanojia S, Wu W, Kono T, Xu J, Osmulski M, Bone RN, Casey N, Evans-Molina C, Sims EK, Spaeth JM
Diabetes 2023 Jun 1;72(6):746-757
Diabetes 2023 Jun 1;72(6):746-757
Budget-Friendly Generation, Biochemical Analyses, and Lentiviral Transduction of Patient-Derived Colon Organoids.
Rigaux E, Chen JW, George F, Lemaire J, Bertrand C, Faugeras L, Fattaccioli A, Gilliaux Q, D'Hondt L, Michiels C, Renard HF, Zanin N
Current protocols 2023 Dec;3(12):e943
Current protocols 2023 Dec;3(12):e943
Colonic L-cell impairment in aged subjects with type 2 diabetes leads to diminished GLP-1 production.
Wang QY, Zhang W, Zhao Y, Chen HL, Liu Q, Wang ZH, Zeng LT, Li J, Chen SJ, Wei L, Iwakuma T, Cai JP
Diabetes & metabolic syndrome 2023 Dec;17(12):102907
Diabetes & metabolic syndrome 2023 Dec;17(12):102907
Profile of chimeric RNAs and TMPRSS2-ERG e2e4 isoform in neuroendocrine prostate cancer.
Wang Q, Chen J, Singh S, Xie Z, Qin F, Shi X, Cornelison R, Li H, Huang H
Cell & bioscience 2022 Sep 10;12(1):153
Cell & bioscience 2022 Sep 10;12(1):153
Shouhui Tongbian Capsule ameliorates constipation via gut microbiota-5-HT-intestinal motility axis.
Bai J, Cai Y, Huang Z, Gu Y, Huang N, Sun R, Zhang G, Liu R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113627
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113627
A novel hypoxia-driven gene signature that can predict the prognosis of hepatocellular carcinoma.
Zeng Z, Lei S, Wang J, Yang Y, Lan J, Tian Q, Chen T, Hao X
Bioengineered 2022 May;13(5):12193-12210
Bioengineered 2022 May;13(5):12193-12210
The Protective Effects of Apigenin Against Radiation-Induced Intestinal Injury.
Liu D, Peng R, Chen Z, Yu H, Wang S, Dong S, Li W, Shao W, Dai J, Li F, Jiang Q, Sun W
Dose-response : a publication of International Hormesis Society 2022 Jul-Sep;20(3):15593258221113791
Dose-response : a publication of International Hormesis Society 2022 Jul-Sep;20(3):15593258221113791
Glycerate from intestinal fructose metabolism induces islet cell damage and glucose intolerance.
Wu Y, Wong CW, Chiles EN, Mellinger AL, Bae H, Jung S, Peterson T, Wang J, Negrete M, Huang Q, Wang L, Jang C, Muddiman DC, Su X, Williamson I, Shen X
Cell metabolism 2022 Jul 5;34(7):1042-1053.e6
Cell metabolism 2022 Jul 5;34(7):1042-1053.e6
Generation and characterization of CRISPR/Cas9-mediated MEN1 knockout BON1 cells: a human pancreatic neuroendocrine cell line.
Monazzam A, Li SC, Wargelius H, Razmara M, Bajic D, Mi J, Bergquist J, Crona J, Skogseid B
Scientific reports 2020 Sep 3;10(1):14572
Scientific reports 2020 Sep 3;10(1):14572
Protein O-GlcNAc Modification Links Dietary and Gut Microbial Cues to the Differentiation of Enteroendocrine L Cells.
Zhao M, Ren K, Xiong X, Cheng M, Zhang Z, Huang Z, Han X, Yang X, Alejandro EU, Ruan HB
Cell reports 2020 Aug 11;32(6):108013
Cell reports 2020 Aug 11;32(6):108013
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 10529-1-AP(CHGA antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 10529-1-AP(CHGA antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas using 10529-1-AP(CHGA antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Chromogranin A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Chromogranin A. This antibody recognizes human antigen. The Chromogranin A antibody has been validated for the following applications: ELISA, IHC analysis.
