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- Product number
- 10427-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10427-2-AP, RRID:AB_2069033
- Product name
- Calnexin antibody
- Antibody type
- Polyclonal
- Description
- Calnexin antibody (Cat. #10427-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exosomes Derived From Mesenchymal Stem Cells Regulating Myotube Cell Atrophy via NF-κB Signaling Pathway.
A panel of serum-derived exosomal miRNAs as markers of cardiovascular risk assessed by carotid intima-media thickness in patients with type 2 diabetes.
Seminal plasma extracellular vesicle-derived miR-296-3p targets PLA2G6 to enhance boar sperm motility by lowering Lys Phosphatidylcholine.
Atrophic Skeletal Muscle-Derived Extracellular Vesicles Transfer miR-125a-5p to Inhibit Bone Formation in Osteoporosis during Aging.
TEAD1 Enhances Exosome Secretion and Promotes Exosome-Mediated Tissue Regeneration.
Ectopic endometrial mesenchymal stem cell-derived exosomal miR-4466 promotes angiogenesis by targeting RUNX1 in adenomyosis.
A GluN2B disease-associated variant promotes the degradation of NMDA receptors via autophagy.
CCPG1-mediated reticulophagy promotes tumorigenesis and cisplatin resistance in bladder cancer.
Establishment of a simple and novel method for contact-dependent intercellular interaction analysis using extracellular vesicles.
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Canine Adipose MSC-Derived Exosomes Ameliorate Skeletal Muscle Injury in Mice.
TRIM27-controlled endothelium-derived exosomes play a central role in podocyte injury in diabetic kidney disease.
Red Blood Cell-Derived Exosomes Deliver Complement C5 to Exacerbate Neuroinflammation and Neuronal Injury after Intracerebral Hemorrhage.
Natural photosynthetic system for restoring homeostasis of animal organelle interaction network.
Complement 5a receptor 2 attenuates diabetic kidney disease by promoting mitochondria-associated endoplasmic reticulum membrane formation mediated by PSS-MFN2 interaction.
Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs-STAT3 Pathway.
Glycosylated NS3/NS3A protein of bluetongue virus facilitates efficient viral egress via lipid raft anchoring.
A dual role for ER-Golgi cargo receptor LMAN1 in supporting CSFV replication and restraining RLR signaling.
Extracellular vesicles derived from live or apoptotic mesenchymal stem cells: comparison of the effects of two extracellular vesicles on liver fibrosis.
Heat stress suppresses lactation through potential rumen-mammary communication mediated by extracellular vesicles: integrated analysis of microbiome, metabolome, and miRNA profiles.
GDF15-Treated iPSC-MSC-Derived Exosomes Alleviate Fibrosis Post-Myocardial Infarction via Repression of the MFAP4/ERK/Drp1 Axis.
Control of lysosome function by the GTPase-activating protein TBC1D9B and its binding partner TMEM55B.
Collagen-Bearing Exosomes from Breast Cancer-Associated Fibroblasts Promote T-cell Dysfunction.
Lung cancer cell-derived exosomal EHF drives M2 macrophage polarization via transcriptional activation of RNF41 to promote tumor progression.
Mechanisms and therapeutic strategies of BiP-HSPA9 axis-mediated endoplasmic reticulum-mitochondria crosstalk driven by bile acids in gastric intestinal metaplasia.
Urinary exosomes aggravate diabetic kidney disease by inducing podocyte ferroptosis via the miR-217/SIRT1/Nrf2 pathway.
Hepatocyte specific Rab27a knockout aggravates metabolic dysfunction associated fatty liver disease.
Ellagic acid alleviates ulcerative colitis in a GPR35-dependent manner associated with SDH restoration.
Plasma exosomal proteomics: Unveiling novel biomarkers for ischemic stroke in the context of diabetes.
Microenvironment-educated MSC-EVs loaded injectable smart hydrogel for targeting senescent nucleus pulposus cells and inhibiting ferroptosis against intervertebral disc degeneration.
PAM-assembled CRISPR-Cas12a activation-based fluorescent and colorimetric dual-modal biosensor for detecting prostate cancer exosomes.
A Natural LDHA Allosteric Inhibitor Geraniin Suppresses Triple-Negative Breast Cancer Cell Growth.
TAMs-derived exosomes promote breast cancer progression by regulating the IRF9/IFI6 axis.
Melatonin-engineered MSCs-exosomes deliver USP4 to stabilise ARNTL and inhibit clock rhythmic ferroptosis for enhanced flap survival.
Circular RNA-based HPV16 therapeutic vaccine elicits potent and durable antitumor immunity.
Ferroptosis-dependent small extracellular vesicles ULK1 enhances mitophagy and suppresses breast cancer migration.
MYC-driven TRIM27 upregulation promotes prostate cancer progression by enhancing CANX ubiquitination and activating PI3K/AKT signaling.
Neuroprotective Effects of Desert Milk Exosomes in LPS-Induced Cognitive Decline: Role of Microglial M2 Polarization and AMPK Signaling.
Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis.
Immunological conversion of triple-negative breast cancer by engineered extracellular vesicle-mediated pyroptosis.
Citicoline Triggers Proteome Remodeling and Proteostatic Adaptation: Evidence from Shotgun Proteomics.
GSTP1-modified exosomes derived from ADMSCs relieve LPS-induced acute lung injury.
Unconventional Secretion of Angiogenic Sonic Hedgehog-Containing Extra-Large Extracellular Vesicles is Driven by PI3K-Rab18-GDP Signalling.
E3 ligase AREL1 controls perinuclear localization of lysosomes and supports Purkinje cell survival.
Proteomics of Prostate Cancer Tissue Small Extracellular Vesicles Reveal Alteration of Metabolism.
Decreased PTGES2 Farnesylation in Granulosa Cells Compromises PGE2-Dependent Cumulus Expansion and Oocyte Maturation During Ovarian Aging.
Multifunctional extracellular vesicles inhibiting autophagy ameliorate immunotherapy in non-small cell lung cancer.
SNRPC promotes chemoresistance in Wilms tumor via the NF-κB-CXCL17 axis regulating M2-Type TAMs infiltration and targeted nanotherapy research.
Neural stem cell-derived exosomal PA2G4 induces ANXA2 degradation to promote mitophagy and alleviate neuronal oxidative stress in cerebral ischemia/reperfusion.
Acutely denervated muscle EVs reshape neuronal mitochondrial metabolism via retrograde signaling to rescue peripheral nerve injury.
Comprehensive analysis of tissue-derived small extracellular vesicles transcriptomic and extensively targeted lipidomics from patients with high-grade serous ovarian cancer.
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis.
POSTN(+) fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling.
STARD3 regulates lysosome positioning and contacts via a GSK3-controlled phosphorylation switch.
Umbilical cord mesenchymal stem cells and their extracellular vesicles attenuate cryopreservation-induced ovarian injury via the suppression of ferroptosis in an in vitro culture system.
Viperin inhibits coronavirus replication by targeting non-structural protein 8 to disrupt replication-transcription complex assembly and RNA-dependent RNA polymerase activity.
Mutant PLP1 impairs COPII vesicle formation via ER calcium depletion in Pelizaeus-Merzbacher disease.
Ascites circRNA ASCOR Drives Platinum Resistance of High-Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation.
EMCV Non-Structural Protein 2C Antagonizes cGAS-STING-Mediated Type I Interferon Signaling via Promoting K48-Linked Polyubiquitination and Degradation of STING.
MiR-423-5p inhibition alleviates podocyte apoptosis in membranous nephropathy by targeting WT1/β-catenin axis.
Mesenchymal stem cells derived EXO-miR3671 delivery promoted angiogenesis and accelerated wound healing of diabetes.
Disruption of spike protein N-glycosylation induces its endoplasmic reticulum retention and attenuates SARS-CoV-2 infectivity.
Efficient hybridoma screening using extracellular vesicles for conformation-specific antibodies to transmembrane proteins.
Exosomal miR-92b-5p regulates N4BP1 to enhance PTEN mono-ubiquitination in doxorubicin-resistant AML.
A single-sEV analysis identifies plasma EPCAM(+) sEVs as a biomarker for early diagnosis and monitoring postoperative remission of thyroid cancer.
Engineered Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Mitigate Liver Fibrosis by Delivering USP10 to Reprogram Macrophage Phenotype.
Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.
Overexpression of miRNA-216 in exosomes derived from umbilical cord mesenchymal stem cells promotes angiogenesis and improves functional recovery after spinal cord injury.
Immunological Safety Evaluation of Exosomes Derived From Human Umbilical Cord Mesenchymal Stem Cells in Mice.
Extracellular Vesicles Derived from FGF2-Primed Astrocytes Against Mitochondrial and Synaptic Toxicities in Parkinson's Disease.
Plasma-derived exosomal miRNAs as potentially novel biomarkers for type 2 diabetes mellitus with abdominal obesity.
Engineered NK92 cell-derived exosomes inhibit ovarian cancer progression by degrading GPRC5A.
Development of a prognostic model for hepatocellular carcinoma based on microvascular invasion characteristic genes by spatial transcriptomics sequencing.
An anti-FAP-scFv-functionalized exosome-carrying hydrogel delivers SKI mRNA to fibrotic nucleus pulposus cells to alleviate intervertebral disc degeneration by regulating FOXO3.
A novel pathway for stemness propagation and chemoresistance in non-small cell lung cancer via phosphorylated PKM2-loaded small extracellular vesicles.
Pharmacological targeting of mitophagy via ALT001 improves herpes simplex virus 1 (HSV1)-mediated microglial inflammation and promotes amyloid β phagocytosis by restricting HSV1 infection.
M1 macrophage-derived exosomal miR-20b promotes radiosensitization via CCND1 in HPV(+) HNSCC.
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
Chaetoglobosin A induces apoptosis in T-24 human bladder cancer cells through oxidative stress and MAPK/PI3K-AKT-mTOR pathway.
Exosomes derived from miR-26a-5p-modified adipose mesenchymal stem cells improve wound healing by targeting MAP2K4.
Curcumin-primed milk-derived extracellular vesicles remodel hair follicle microenvironment for the treatment of androgenetic alopecia.
Development of serum glycosylated exosomal microRNAs as biomarkers for early diagnosis of lung adenocarcinoma.
EMAP-II from macrophage-derived extracellular vesicles drives neutrophil extracellular traps formation via PI3K/AKT/mtROS in lung ischemia/reperfusion injury.
Exosome-derived lnc-FAM72D-3 promotes lenvatinib resistance by remodeling hepatocellular carcinoma cytoskeleton via MBNL1/FAK axis.
M2 Macrophages-Derived Exosomes Inhibited Podocyte Pyroptosis via lncRNA AFAP1-AS1/EZH2 Axis.
3D-printed advanced scaffold armed with exosomes derived from human skeletal stem cell identified by single-cell RNA sequencing enhances osteochondral regeneration.
Glyphosate targets FYN to regulate glycolysis and promote glioblastoma proliferation: A network toxicology study.
Endometrial Mesenchymal Stem Cell-Derived Exosomal miR-4669 Promotes EMT in Adenomyosis by Inducing M2 Macrophage Polarization via the DUSP6/ERK Pathway.
Disulfide bond-mediated stabilization of the oligomers of UDP-glucuronosyltransferase 2B7.
IAV NS1 carried by exosomes promotes IL-10 production by the PI3K-AKT-GSK3β-CREB pathway.
Multidimensional Engineering of Extracellular Vesicles for Targeted Delivery and Microglial Reprograming in Spinal Cord Injury Repair.
MiR-7683-3p from M2-exosomes attenuated atherosclerosis by activating the PPARγ-LXRα-ABCG1 pathway mediated cholesterol efflux of vascular smooth muscle cell derived foam cells.
MSCs-EXOs containing miR-21a-5p promoted cell proliferation in the rat retinal Müller cell rMC-1 via targeting LATS1.
Comprehensive multiomic analysis of extracellular vesicles from Mycoplasma bovis-infected bovine mammary epithelial cells identifies proteins and miRNAs that induce inflammatory responses in macrophages.
Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia.
Exosomes from small intestinal epithelium mediate cardiac fibrosis during aging.
Ellagic Acid-Loaded sEVs Encapsulated in GelMA Hydrogel Accelerate Diabetic Wound Healing by Activating EGFR on Skin Repair Cells.
AntagomiR-192-5p-engineered exosomes encapsulated in MXene-modified GelMA hydrogel facilitated epithelization of burn wounds by targeting OLFM4.
Mevalonate metabolites boost aged oocyte quality through prenylation of small GTPases.
Umbilical cord blood-derived exosomes deliver miR-182-5p to Therapeutically target the MYD88/NF-κB signaling pathway in rat peri-implantitis.
Suppression of SREBP by a transmembrane protein mutated in cardiomyopathy.
The exosomal miRNA-3184-3p derived from highly metastatic melanoma cells promotes metastatic competency via the positive feedback loop of NLK/Wnt/S100A11.
ATP2A2 regulates STING1/MITA-driven signal transduction including selective autophagy.
Urinary extracellular vesicle RNAs as novel biomarkers for diagnosis and prognosis of lupus nephritis.
Exosome-derived hsa_circ_0007132 promotes lenvatinib resistance by inhibiting the ubiquitin-mediated degradation of NONO.
Exosomal miR-382-5p prevents pre-metastatic niche formation by inhibiting GPR176/GNAS-CXCR1/CXCR2 axis in colorectal cancer liver metastasis.
POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?
Exosome-Based Proteomic Profiling for Biomarker Discovery in Pediatric Fabry Disease: Insights into Early Diagnosis Monitoring.
Exosomal miR-122-5p from tubular cells ameliorates renal interstitial fibrosis by regulating fibroblasts via HIF-1α.
Pak4-mediated crosstalk between necroptotic macrophages and tendon stem/progenitor cells contributes to traumatic heterotopic ossification formation.
Extracellular vesicles derived from menstrual blood-derived mesenchymal stem cells suppress inflammatory atherosclerosis by inhibiting NF-κB signaling.
The APOE ε4 allele affects the survival of patients with Parkinson's disease independent of dementia.
Bta-miR-199a-3p in embryonic bovine lung cells-derived extracellular vesicles enhances pro-inflammatory cytokine expression in macrophages via DUSP5 upregulation during Mycoplasma bovis infection.
The significance of urine extracellular vesicle DNA methylation detection in the diagnosis and classification of prostate cancer.
Dual-targeting exosome vaccine confers efficient protection against CVB3-induced myocarditis.
RAB22A triggers intercellular chemoresistance transmission in colorectal cancer by promoting exosome release via the PKM2-pSNAP23 axis.
M2 Macrophage-Derived Migrasomes Mediate Ischaemia-Induced Retinal Neovascularization by Targeting TREM2.
Gastric cancer-derived exosomal miR-196a-5p remodels the pre-metastatic niche for peritoneal dissemination.
Glabridin-Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity.
Serum exosomal lncRNA LINC00472 combined with serum CK-MB and cTnI as diagnostic biomarker for acute myocardial infarction.
Mfn2 Regulates Scleral Remodeling in Myopia by Maintaining Endoplasmic Reticulum Homeostasis in Scleral Fibroblasts.
Antihypertension and Improvement Effects of Hexapeptide APPLRP on Exosomes-Mediated Vascular Endothelial Inflammation in Spontaneously Hypertensive Rats.
Study on the Mechanism of Acanthopanax senticosus Extract Intervening in the Regulation of Parkinson's Disease by BV2 Microglial Cell-Derived Exosomes.
Extracellular vesicle derived miRNAs from plasma as promising diagnosis and prognosis biomarkers for neuroblastoma.
Fusobacterium nucleatum-derived extracellular vesicles carrying virulence factor DNA trigger AIM2 inflammasome activation to facilitate UC progression.
Epigenetic silencing of MSTN via m6A modification underlies the renoprotective effects of engineered MSC exosomes with RBM15 depletion in diabetic nephropathy.
Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Transfer CD59 to Astrocytes to Alleviate Complement-Dependent Cytotoxicity.
Characteristics of extracellular vesicle-derived lncRNAs during the progression of HBV-related hepatocellular carcinoma.
Construction of a prognostic model for nasopharyngeal carcinoma based on serum exosomal circular RNAs and analysis of immune microenvironment.
MiR-519d-3p from Placenta-Derived Exosomes Induce Immune Intolerance Regulating Immune Cells, Contributing to the Pathogenesis of Preeclampsia.
Exosomes Derived From BMMSCs Promote B10 Cell Differentiation but Not IL-10 Production.
Lipid droplets restrict phagosome formation in antifungal immunity.
The ER protein CANX (calnexin)-mediated autophagy protects against alzheimer disease.
Targeting capacity, safety and efficacy of engineered extracellular vesicles delivered by transdermal microneedles to treat plasmacytoma in mice.
Syntaxin 17 Translocation Mediated Mitophagy Switching Drives Hyperglycemia-Induced Vascular Injury.
HucMSCs-Derived Extracellular Vesicles Deliver RPS27A Protein to Manipulate the MDM2-P53 Axis and Ameliorate Neurological Dysfunction in Parkinson's Disease.
Extracellular vesicles derived from bone marrow mesenchymal stem cells regulate SREBF2/HMGB1 axis by transporting miR-378a-3p to inhibit ferroptosis in intestinal ischemia-reperfusion injury.
Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response.
Exosomal miR-432-5p, miR-4433b-5p, and miR-599: Biomarkers for Monitoring the Severity of Anti-N-methyl-D-aspartate Receptor Encephalitis.
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma.
Chaihu-Shugan-San alleviates post-stroke depression in mice: Mechanistic insights into exosome-mediated neuroprotection.
Evaluating the feasibility of gene replacement strategies to treat MTRFR deficiency.
AKAP1/PKA-mediated GRP75 phosphorylation at mitochondria-associated endoplasmic reticulum membranes protects cancer cells against ferroptosis.
Aggregated proinsulin in pancreatic β-cells is degraded by the autophagy pathway.
Exosomal miR-184 facilitates bladder cancer progression by targeting AKR1C3 and inducing immune escape via IRF2-CXCL10 axis.
Inducible global knockout of surfeit locus protein 4 in adult mice results in hypolipidemia, intestinal lipid accumulation, liver injury, and increased mortality.
Extracellular vesicle-packaged PKM2 from endometriotic stromal cells promotes endometrial collagen I deposition by inhibiting autophagy in endometriosis.
Extracellular vesicular delivery of ceramides from pulmonary macrophages to endothelial cells facilitates chronic obstructive pulmonary disease.
Extracellular vesicles derived from mesenchymal stem cells ameliorate sulfur mustard-induced lung injury by regulating apoptosis via miR-146a-5p.
STT3B promotes porcine epidemic diarrhea virus replication by regulating N-glycosylation of PEDV S protein.
Organelle-tuning condition robustly fabricates energetic mitochondria for cartilage regeneration.
Exosomes containing miR-152-3p targeting FGFR3 mediate SLC7A7-induced angiogenesis in bladder cancer.
Static Topographical Cue Combined with Dynamic Fluid Stimulation Enhances the Macrophage Extracellular Vesicle Yield and Therapeutic Potential for Bone Defects.
Mannose-modified exosomes loaded with MiR-23b-3p target alveolar macrophages to alleviate acute lung injury in Sepsis.
E-jet 3D printed aligned nerve guidance conduits incorporated with decellularized extracellular matrix hydrogel encapsulating extracellular vesicles for peripheral nerve repair.
Multifunctional magneto-electric and exosome-loaded hydrogel enhances neuronal differentiation and immunoregulation through remote non-invasive electrical stimulation for neurological recovery after spinal cord injury.
Exosomal miR-196a-5p Secreted by Bone Marrow Mesenchymal Stem Cells Inhibits Ferroptosis and Promotes Drug Resistance of Acute Myeloid Leukemia.
Engineered Extracellular Vesicles Loaded with MiR-100-5p Antagonist Selectively Target the Lesioned Region to Promote Recovery from Brain Damage.
Antimicrobial dual-crosslinked hydrogel synergizes bioengineered extracellular vesicles for enhanced diabetic wound healing.
Endoscopic nasal delivery of engineered endothelial progenitor cell-derived exosomes improves angiogenesis and neurological deficits in rats with intracerebral hemorrhage.
Charge-reversed small extracellular vesicles from human adipose-derived mesenchymal stromal cells attenuate renal fibrosis postacute kidney injury by inhibiting epithelial-mesenchymal transition progression in SD rat model.
Senescent cartilage endplate stem cells-derived exosomes induce oxidative stress injury in nucleus pulposus cells and aggravate intervertebral disc degeneration by regulating FOXO3.
Macrophages-derived small extracellular vesicles regulate chondrocyte proliferation and affect osteoarthritis progression via upregulating Osteopontin expression.
Targeting RPSA to modulate endosomal trafficking and amyloidogenesis in genetic Alzheimer's disease.
YTHDF1 differentiates the contributing roles of mTORC1 in aging.
Brain-derived exosomal hemoglobin transfer contributes to neuronal mitochondrial homeostasis under hypoxia.
Protocol for isolating extracellular vesicles from human or mouse airway macrophages for functional assays and in vivo or in vitro experimentation.
Loss of Bbs8 leads to cystic kidney disease in mice with reduced acetylation of ciliary alpha-tubulin through HDAC2.
The crosstalk between lung adenocarcinoma cells and M2 macrophages promotes cancer cell development via the SFRS1/miR-708-5p/PD-L1 axis.
Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
Exploring Exosome Contributions to Gouty Arthritis: A Proteomics and Experimental Study.
Ultrasound-Guided Functionalized Extracellular Vesicles for Visualized, Controlled, and Efficient Renal Delivery for Enhanced Kidney Repair.
Embryonic stem cell-derived small extracellular vesicles alleviate lead-induced cochlear spiral ganglion neurons injury by activating PI3 K/AKT signaling pathway.
Low-intensity pulsed ultrasound as a strategy to boost exosome secretion by adipose-derived stem cells and uptake for myocardial infarction therapy.
Zika virus disrupts steroidogenesis and impairs spermatogenesis by stalling the translation of CYP17A1 mRNA.
Injectable HAMA-CPC hydrogels loaded with high-yield 3D bioprinted adipose-derived stem cell small extracellular vesicles for increased bone repair.
Design, synthesis and biological evaluation of novel β-caryophyllene derivatives as potential anti-cancer agents through the ROS-mediated apoptosis pathway.
Exosomal miRNA Profiling in Liquid Biopsy of Vitreous in Proliferative Diabetic Retinopathy.
Yellow Fever Virus Interactomes Reveal Common and Divergent Strategies of Replication and Evolution for Mosquito-borne Flaviviruses.
The Lipid Droplet Protein DHRS3 Is a Regulator of Melanoma Cell State.
Enhancing epithelial regeneration with gelatin methacryloyl hydrogel loaded with extracellular vesicles derived from adipose mesenchymal stem cells for decellularized tracheal patching.
BBSome-deficient cells activate intraciliary CDC42 to trigger actin-dependent ciliary ectocytosis.
Calcium-mediated mitochondrial fission and mitophagy drive glycolysis to facilitate arterivirus proliferation.
Lipidomic and transcriptomic characteristics of boar seminal plasma extracellular vesicles associated with sperm motility.
Improved Predictability of Diagnosis and Prognosis Using Serum- and Tissue-Derived Extracellular Vesicles From Bulk mRNA Sequencing in Pancreatic Ductal Adenocarcinoma.
A novel de novo GABRA2 gene missense variant causing developmental epileptic encephalopathy in a Chinese patient.
Efficient Isolation and Characterization Methods for Chicken Serum Extracellular Vesicles.
Inhibition of macrophage polarization and pyroptosis in collagen-induced arthritis through MSC-exo and ginsenoside Rh2.
Exosomal NEDD4L derived from HG+oxLDL-induced vascular endothelial cells accelerates macrophage M1 polarization and oxLDL uptake by ubiquitinating IκBα and PPARγ.
Ubiquitin ligase MARCH5 controls the formation of mitochondria-derived pre-peroxisomes.
Exosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity.
One-dimensional nanosonosensitizer boosted multiple branches of immune responses against MHC-deficient immune-evasive urologic tumor.
Dental pulp stem cell-derived intracellular vesicles prevent orthodontic relapse by inhibiting PI3K/Akt/NF-κB-mediated osteoclast activity.
The Expression Pattern and Functional Analysis of Extracellular Vesicle Long Non-Coding RNAs from Uterine Fluid During Implantation in Pig.
Four-dimensional trapped ion mobility spectrometry proteomics reveals circulating extracellular vesicles encapsulated drivers of nasopharyngeal carcinoma distant dissemination.
Choline kinase alpha regulates autophagy-associated exosome release to promote glioma cell progression.
HIF-1α/BNIP3-Mediated Endoplasmic Reticulum Degradation via Autophagy Protects Against Ischemia Reperfusion-Induced Acute Kidney Injury.
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy.
PNPO-Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β-Catenin Pathway.
Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3.
Genomewide Screen Identifies Peroxisomal Role in APOL1 Podocytopathy.
Metabolomic and Proteomic Profiling of Serum-Derived Extracellular Vesicles from Early-Stage Amyotrophic Lateral Sclerosis Patients.
Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury.
3D-cultured DFAT spheroid-derived exosomes promote aged wound healing via modulation of the NF-κB/Serpine1 pathway.
Non-genetic inactivation of caspase-3 and P53 increases cancer cell fitness by PDIA4 redistribution.
Mesenchymal stem cell-derived small extracellular vesicles-loaded GelMA microspheres enhance diabetic wound healing by promoting M2 macrophage polarization through p38 MAPK inhibition.
TLyp-1-modified exosome-mediated delivery of circRAPGEF5 ASO inhibits lung adenocarcinoma metastasis via regulating the miR-570-3p/SPP1 axis.
Engineered BMSC-derived exosomes deliver miR-17-5p inhibitor to restore sensory conduction via the IL-11/GP130/STAT3/GAP-43 axis in dorsal column lesion.
Dietary monounsaturated fatty acid facilitates lipid droplet turnover through chaperone HSP90A-mediated lysosomal degradation of PLIN2 in hepatocellular carcinoma.
GSTK1 and RETREG1/FAM134B-mediated reticulophagy attenuates tubular injury in diabetic nephropathy through endoplasmic reticulum stress and apoptosis.
CKAP4 in Extracellular Vesicle-Derived From Podocyte Serves as a Non-Invasive Diagnostic Biomarker for Diabetic Nephropathy and Promotes Vascular Calcification.
ERβ/circAHNAK Axis Inhibits USP10-FMR1 Deubiquitination to Prevent m⁶A-Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma.
Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection.
Macrophage-derived exosomal miR-466i-5p and miR-365-2-5p stimulated by BMP-2 promote osteogenesis.
Microglia-specific interleukin-4 delivery by engineered extracellular vesicles restores inner blood-retinal barrier in diabetic retinopathy via GAS6-MERTK pathway.
Atosiban-conjugated 3WJ-pRNA nanoparticles delivering GAS1-enhanced extracellular vesicles: targeting the decidua to combat recurrent miscarriage.
Liver-breast communication of adipocyte-oriented exosomes drives primary mammary cancer progression.
SPLiCR-seq: A CRISPR-Based Screening Platform for RNA splicing Identifies Novel Regulators of IRE1α-XBP1 Signaling Under ER Stress.
MSC-sEV Promote Regeneration of Cochlear Spiral Ganglion Neurons and Myelin Sheaths in 3D Culture System.
Urine-Derived CD105-Positive Exosome Promotes Macrophage M1 Polarization Through the TGF-β1/Smad3 Signaling Axis To Exacerbate Lupus Nephritis.
β-caryolane derivatives as novel anti-colorectal cancer agents: synthesis and in vitro biological evaluation.
Exosomal miR-223-3p from mesenchymal stem cells targets FBXW7 to inhibit intervertebral disc degeneration: mechanism insights.
Ubiquitination by HRD1 is essential for TLR3 trafficking and its innate immune signaling.
De-ubiquitinase USP35 promotes peritoneal dissemination of gastric cancer by regulating metabolic reprogramming.
RalGAP complexes control secretion and primary cilia in pancreatic disease.
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice.
Deciphering the Proteomic Landscape of Circulating Extracellular Vesicles in Human Abdominal Aortic Aneurysm.
Vascular Smooth Muscle-Secreted Exosomal X26nt Impedes Atherosclerosis Progression via the c-FOS/XBP1/SOD1 Axis.
Exosomal miR-218 secreted from endothelial progenitor cells mitigates acute lung injury in sepsis mice by inhibiting HMGA1 in alveolar macrophages.
The foam cell-derived exosomes exacerbate ischemic white matter injury via transmitting metabolic defects to microglia.
Proteomic Analysis of Differentially Expressed Plasma Exosome Proteins in Heat-Stressed Holstein cows.
Exosomal Biglycan promotes gastric cancer progression via M2 polarization and CXCL10-mediated JAK/STAT1 activation.
Deletion of SH2D5 alleviates epileptic seizures and NMDAR expression via autophagic degradation of STAT1.
Engineered MEVs for photoreceptor-targeted delivery of USP25 to alleviate diabetic retinopathy.
hUC-MSCs and derived exosomes attenuate DEX-induced muscle atrophy through modulation of estrogen signaling pathway.
A functionally tunable magnetic nanochains platform for N-glycoproteomic analysis of extracellular vesicles from ultratrace biofluids.
MRO/HNRNPU/CCL5 feedback loop amplifies M2 macrophage and breast cancer cell crosstalk to drive progression.
Host sphingolipids support Plasmodium berghei liver stage development.
Olfactory mucosa mesenchymal stem cell-derived exosomes protect against neuroinflammation after subarachnoid hemorrhage by activating mitophagy.
Sustained release of miR-21 carried by mesenchymal stem cell-derived exosomes from GelMA microspheres inhibits ovarian granulosa cell apoptosis in premature ovarian insufficiency.
Upregulation of ISG15 induced by MAPT/tau accumulation represses autophagic flux by inhibiting HDAC6 activity: a vicious cycle in Alzheimer disease.
LIMA1 O-GlcNAcylation Promotes Hepatic Lipid Deposition through Inducing β-catenin-Regulated FASn Expression in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Induced Pluripotent Stem Cell-Derived Exosomes Promote Peripheral Nerve Regeneration in a Rat Sciatic Nerve Crush Injury Model: A Safety and Efficacy Study.
Peptidomic profiling of mesenchymal stem cell-derived extracellular vesicles and anti-inflammatory activity of degraded peptides.
Astrocyte-Derived Extracellular Vesicles Alleviate Optic Nerve Injury Through Remodeling of Retinal Microenvironmental Homeostasis.
Muscle-derived small extracellular vesicles induce liver fibrosis during overtraining.
Transcriptomic analysis of plasma-derived small extracellular vesicles reveals the pathological characteristics of normal tension glaucoma.
MAPK1 Mediates MAM Disruption and Mitochondrial Dysfunction in Diabetic Kidney Disease via the PACS-2-Dependent Mechanism.
Metabolic Reprogramming of CD4(+) T Cells by Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuates Autoimmune Hepatitis Through Mitochondrial Protein Transfer.
Non-Clinical Safety Evaluation of Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells in Cynomolgus Monkeys.
Pretreatment of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes with Quercetin Enhances the Healing of Diabetic Skin Wounds by Modulating Host-Microbiota Interactions.
Key Magnetized Exosomes for Effective Targeted Delivery of Doxorubicin Against Breast Cancer Cell Types in Mice Model.
M1 Microglia-Derived Exosomes Promote A1 Astrocyte Activation and Aggravate Ischemic Injury via circSTRN3/miR-331-5p/MAVS/NF-κB Pathway.
MiRNAs and Neutrophil-Related Membrane Proteins from Plasma-Derived Extracellular Vesicles for Early Prediction of Organ Dysfunction and Prognosis in Septic Patients.
Immunomodulatory effect of PLGA-encapsulated mesenchymal stem cells-derived exosomes for the treatment of allergic rhinitis.
Influential factors on urine EV DNA methylation detection and its diagnostic potential in prostate cancer.
Photoreceptor-targeted extracellular vesicles-mediated delivery of Cul7 siRNA for retinal degeneration therapy.
Engineered nanovesicles from activated neutrophils with enriched bactericidal proteins have molecular debridement ability and promote infectious wound healing.
Adipose mesenchymal stem cell-derived exosomes promote skin wound healing in diabetic mice by regulating epidermal autophagy.
mRNA expression profiles in muscle-derived extracellular vesicles of Large White and wild boar piglets reveal their potential roles in immunity and muscle phenotype.
CircPRRC2C Promotes the Oncogenic Phenotypes of Laryngeal Squamous Cell Carcinoma Cells via MiR-136-5p/HOXD11 Axis.
The expression profile of brain-derived exosomal miRNAs reveals the key molecules responsible for spontaneous motor function recovery in a rat model with permanent middle cerebral artery occlusion.
Human Umbilical Cord Mesenchymal Stem Cells-Derived Extracellular Vesicles for Rat Jawbone Regeneration in Periapical Periodontitis.
Discovery of novel quinoline scaffold selective estrogen receptor degraders (SERDs) for treatment of ER positive breast cancer with enhanced antiproliferative bioactivity through immunogenic cell death (ICD) effects.
Rate of hydrolysis of the phosphate esters of B vitamins is reduced by zinc deficiency: In vitro and in vivo.
The Delayed Turnover of Proteasome Processing of Myocilin upon Dexamethasone Stimulation Introduces the Profiling of Trabecular Meshwork Cells' Ubiquitylome.
Circulating exosomal circRNA-miRNA-mRNA network in a familial partial lipodystrophy type 3 family with a novel PPARG frameshift mutation c.418dup.
Stereotactically intracerebral transplantation of neural stem cells for ischemic stroke attenuated inflammatory responses and promoted neurogenesis: an experimental study with monkeys.
EPDR1 promotes PD-L1 expression and tumor immune evasion by inhibiting TRIM21-dependent ubiquitylation of IkappaB kinase-β.
Functional exosomes modified with chitosan effectively alleviate anthracycline-induced cardiotoxicity.
Research on the role of exosomes secreted by immortalized adipose-derived mesenchymal stem cells differentiated into pericytes in the repair of high glucose-induced retinal vascular endothelial cell damage.
Exosomes Derived from Rejuvenated Stem Cells Inactivate NLRP3 Inflammasome and Pyroptosis of Nucleus Pulposus Cells via the Transfer of Antioxidants.
Pharmacological chaperones restore proteostasis of epilepsy-associated GABA(A) receptor variants.
Intratympanic injection of MSC-derived small extracellular vesicles protects spiral ganglion neurons from degeneration.
Milk-Derived Extracellular Vesicles Carrying ssc-let-7c Alleviate Early Intestinal Inflammation and Regulate Macrophage Polarization via Targeting the PTEN-Mediated PI3K/Akt Pathway.
Bioenergetic-active exosomes for cartilage regeneration and homeostasis maintenance.
Priming Mesenchymal Stem Cells with Lipopolysaccharide Boosts the Immunomodulatory and Regenerative Activity of Secreted Extracellular Vesicles.
Quercetin inhibits endothelial & hepatocellular carcinoma cell crosstalk via reducing extracellular vesicle-mediated VEGFR2 mRNA transfer.
Comparative investigation of exosome extraction from rat bone marrow mesenchymal stem cells using three different methodologies.
Ammonia-induced lysosomal and mitochondrial damage causes cell death of effector CD8(+) T cells.
Kinesin-1 mediates proper ER folding of the Ca(V)1.2 channel and maintains mouse glucose homeostasis.
Jiedu recipe, a compound Chinese herbal medicine, suppresses hepatocellular carcinoma metastasis by inhibiting the release of tumor-derived exosomes in a hypoxic microenvironment.
PlexinA1 (PLXNA1) as a novel scaffold protein for the engineering of extracellular vesicles.
Zosuquidar Promotes Antitumor Immunity by Inducing Autophagic Degradation of PD-L1.
EP152R-mediated endoplasmic reticulum stress contributes to African swine fever virus infection via the PERK-eIF2α pathway.
Time-series metabolomic analysis revealed altered metabolism of cynomolgus monkeys after injecting exosomes.
Mesenchymal stromal cells deliver H(2)S-enhanced Nrf2 via extracellular vesicles to mediate mitochondrial homeostasis for repairing hypoxia-ischemia brain damage.
Pancreatic cancer-derived exosomal miR-510 promotes macrophage M2 polarization and facilitates cancer cell aggressive phenotypes.
Treatment of Parkinson's disease model with human umbilical cord mesenchymal stem cell-derived exosomes loaded with BDNF.
Plasma exosomes impair microglial degradation of α-synuclein through V-ATPase subunit V1G1.
Effect of human periodontal ligament stem cell-derived exosomes on cementoblast activity.
Analysis of the effects of M2 macrophage-derived PDE4C on the prognosis, metastasis and immunotherapy benefit of osteosarcoma.
Macrophage-derived ectosomal miR-350-3p promotes osteoarthritis progression through downregulating chondrocyte H3K36 methyltransferase NSD1.
Lipotoxic hepatocyte derived LIMA1 enriched small extracellular vesicles promote hepatic stellate cells activation via inhibiting mitophagy.
mir-605-3p prevents liver premetastatic niche formation by inhibiting angiogenesis via decreasing exosomal nos3 release in gastric cancer.
ANXA3-Rich Exosomes Derived from Tumor-Associated Macrophages Regulate Ferroptosis and Lymphatic Metastasis of Laryngeal Squamous Cell Carcinoma.
Exosome-mediated Delivery of miR-519e-5p Promotes Malignant Tumor Phenotype and CD8+ T-Cell Exhaustion in Metastatic PTC.
An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins.
Detection of fucosylated extracellular vesicles miR-4732-5p related to diagnosis of early lung adenocarcinoma by the electrochemical biosensor.
Low‑intensity pulsed ultrasound accelerates diabetic wound healing by ADSC‑derived exosomes via promoting the uptake of exosomes and enhancing angiogenesis.
Transcriptome sequencing of circular RNA reveals the involvement of hsa-SCMH1_0001 in the pathogenesis of Parkinson's disease.
Exosome co-delivery of a STING agonist augments immunogenicity elicited by CVB3 VP1 vaccine via promoting antigen cross-presentation of CD8 (+) DCs.
Combinatorial selective ER-phagy remodels the ER during neurogenesis.
Chemical Proteomics Reveals N(ε)-Fatty-Acylation of Septins by Rho Inactivation Domain (RID) of the Vibrio MARTX Toxin to Alter Septin Localization and Organization.
Intracerebral fate of organic and inorganic nanoparticles is dependent on microglial extracellular vesicle function.
SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins.
NDUFS4 regulates cristae remodeling in diabetic kidney disease.
The lipid droplet protein DHRS3 is a regulator of melanoma cell state.
Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis.
Metabolic profiling in tissues and urine of patients with prostatic lesions and the diagnostic value of urine extracellular vesicles metabolites in prostate cancer.
Exosomes derived from umbilical cord mesenchymal stem cells ameliorate male infertility caused by busulfan in vivo and in vitro.
Peritumoral SPARC expression induced by exosomes from nasopharyngeal carcinoma infected Epstein-Barr virus: A poor prognostic marker.
A virally encoded high-resolution screen of cytomegalovirus dependencies.
Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting.
ZNT5-6 and ZNT7 play an integral role in protein N-glycosylation by supplying Zn(2+) to Golgi α-mannosidase II.
Exosomal lncRNA-MIAT promotes neovascularization via the miR-133a-3p/MMP-X1 axis in diabetic retinopathy.
Plasma exosomes from patients with active thyroid-associated orbitopathy induce inflammation and fibrosis in orbital fibroblasts.
Extracellular vesicles activated cancer-associated fibroblasts promote lung cancer metastasis through mitophagy and mtDNA transfer.
Macrophage Phenotype Induced by Circulating Small Extracellular Vesicles from Women with Endometriosis.
Engineered extracellular vesicle-based gene therapy for the treatment of discogenic back pain.
Reducing Oxidative Stress-Mediated Alcoholic Liver Injury by Multiplexed RNAi of Cyp2e1, Cyp4a10, and Cyp4a14.
N6-Methyladenosine enhances the translation of ENO1 to promote the progression of bladder cancer by inhibiting PCNA ubiquitination.
M1 macrophage-derived exosomes inhibit cardiomyocyte proliferation through delivering miR-155.
Yoda1 pretreated BMSC derived exosomes accelerate osteogenesis by activating phospho-ErK signaling via Yoda1-mediated signal transmission.
Astragaloside IV promotes exosome secretion of endothelial progenitor cells to regulate PI3KR2/SPRED1 signaling and inhibit pyroptosis of diabetic endothelial cells.
Osteoblast-derived exosomes promote osteogenic differentiation of osteosarcoma cells via URG4/Wnt signaling pathway.
Human umbilical cord mesenchymal stem cells improve disease characterization of Sjogren's syndrome in NOD mice through regulation of gut microbiota and Treg/Th17 cellular immunity.
Nuclear membrane protein SUN2 promotes replication of flaviviruses through modulating cytoskeleton reorganization mediated by NS1.
Lactate-lactylation-HSPA6 axis promotes PRRSV replication by impairing IFN-β production.
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral disc.
Delphinidins from Maqui Berry (Aristotelia chilensis) ameliorate the subcellular organelle damage induced by blue light exposure in murine photoreceptor-derived cells.
PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4.
Single-molecule localization microscopy reveals STING clustering at the trans-Golgi network through palmitoylation-dependent accumulation of cholesterol.
Tumor-associated macrophage-derived exosomal miR-513b-5p is a target of jianpi yangzheng decoction for inhibiting gastric cancer.
The effects of boar seminal plasma extracellular vesicles on sperm fertility.
Adapting the endoplasmic reticulum proteostasis rescues epilepsy-associated NMDA receptor variants.
Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis.
UBXN1 maintains ER proteostasis and represses UPR activation by modulating translation.
MiR-141-3p-Functionalized Exosomes Loaded in Dissolvable Microneedle Arrays for Hypertrophic Scar Treatment.
Interorgan communication in neurogenic heterotopic ossification: the role of brain-derived extracellular vesicles.
SYNJ2BP ameliorates intervertebral disc degeneration by facilitating mitochondria-associated endoplasmic reticulum membrane formation and mitochondrial Zn(2+) homeostasis.
M2 macrophage-derived exosomal miR-26b-5p regulates macrophage polarization and chondrocyte hypertrophy by targeting TLR3 and COL10A1 to alleviate osteoarthritis.
Maternal fiber-rich diet promotes early-life intestinal development in offspring through milk-derived extracellular vesicles carrying miR-146a-5p.
OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB.
Glutamine sensing licenses cholesterol synthesis.
Novel injectable adhesive hydrogel loaded with exosomes for holistic repair of hemophilic articular cartilage defect.
Tissue nano-transfection of antimicrobial genes drives bacterial biofilm killing in wounds and is potentially mediated by extracellular vesicles.
NEDD4L-mediated RASGRP2 suppresses high-glucose and oxLDL-induced vascular endothelial cell dysfunctions by activating Rap1 and R-Ras.
Homozygous variant in translocase of outer mitochondrial membrane 7 leads to metabolic reprogramming and microcephalic osteodysplastic dwarfism with moyamoya disease.
Immunomodulatory effect of mesenchymal stem cells-derived extracellular vesicles to modulate the regulatory T cells and Th1/Th2 imbalance in peripheral blood mononuclear cells of patients with allergic rhinitis.
Opposing regulation of the STING pathway in hepatic stellate cells by NBR1 and p62 determines the progression of hepatocellular carcinoma.
Synthesis, anticancer and antibacterial evaluation of novel spiramycin-acylated derivatives.
The Microenvironment in an Experimental Model of Acute Pancreatitis Can Modify the Formation of the Protein Corona of sEVs, with Implications on Their Biological Function.
Adipose-derived stem cell exosomes attenuates myofibroblast transformation via inhibiting autophagy through TGF-β/Smad2 axis in oral submucosal fibrosis.
Osteoblast-derived exosomal miR-140-3p targets ACER2 and increases the progression of prostate cancer via the AKT/mTOR pathway-mediated inhibition of autophagy.
Ectopic endometrial stromal cell-derived extracellular vesicles encapsulating microRNA-25-3p induce endometrial collagen I deposition impairing decidualization in endometriosis.
Functional multi-organelle units control inflammatory lipid metabolism of macrophages.
Circulating small extracellular vesicle RNA profiling for the detection of T1a stage colorectal cancer and precancerous advanced adenoma.
AGFG1 increases cholesterol biosynthesis by disrupting intracellular cholesterol homeostasis to promote PDAC progression.
Postprandial exercise regulates tissue-specific triglyceride uptake through angiopoietin-like proteins.
N-desmethyldauricine from Menispermum dauricum DC suppresses triple-negative breast cancer growth in 2D and 3D models by downregulating the NF-κB signaling pathway.
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Cerebrospinal fluid exosomal microRNAs as biomarkers for diagnosing or monitoring the progression of non-small cell lung cancer with leptomeningeal metastases.
Detecting early-warning biomarkers associated with heart-exosome genetic-signature for acute myocardial infarction: A source-tracking study of exosome.
Cartilage stem/progenitor cells-derived exosomes facilitate knee cartilage repair in a subacute osteoarthritis rat model.
Extracellular vesicles derived from M2-like macrophages alleviate acute lung injury in a miR-709-mediated manner.
Perilipin membrane integration determines lipid droplet heterogeneity in differentiating adipocytes.
Zinc and manganese homeostasis closely interact in mammalian cells.
Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis.
Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
Mesenchymal Stem Cell-Derived Exosomes Promote Recovery of The Facial Nerve Injury through Regulating Macrophage M1 and M2 Polarization by Targeting the P38 MAPK/NF-Κb Pathway.
Common Markers and Small Molecule Inhibitors in Golgi Studies.
Immunofluorescence Microscopy of the Mammalian Golgi Apparatus.
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones.
Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials.
Identification of hsa-miR-619-5p and hsa-miR-4454 in plasma-derived exosomes as a potential biomarker for lung adenocarcinoma.
Human umbilical cord mesenchymal stem cells derived extracellular vesicles alleviate salpingitis by promoting M1-to-M2 transformation.
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution.
MAVI1, an endoplasmic reticulum-localized microprotein, suppresses antiviral innate immune response by targeting MAVS on mitochondrion.
Novel neutrophil extracellular trap-related mechanisms in diabetic wounds inspire a promising treatment strategy with hypoxia-challenged small extracellular vesicles.
Amelioration of ethanol-induced oxidative stress and alcoholic liver disease by in vivo RNAi targeting Cyp2e1.
Fluorescence Tracking of Small Extracellular Vesicles In Vivo.
Enhanced wound healing and hemostasis with exosome-loaded gelatin sponges from human umbilical cord mesenchymal stem cells.
FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson's disease via m6A-dependent regulation of ATM mRNA.
Small RNA sequencing analysis of exosomes derived from umbilical plasma in IUGR lambs.
The Exosome-Transmitted lncRNA LOC100132249 Induces Endothelial Dysfunction in Diabetic Retinopathy.
Proteomic Investigation of Differential Interactomes of Glypican 1 and a Putative Disease-Modifying Variant of Ataxia.
Lens epithelial cell-derived exosome inhibits angiogenesis in ocular pathological neovascularization through its delivery of miR-146a-5p.
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
Plasma extracellular vesicle long RNAs predict response to neoadjuvant immunotherapy and survival in patients with non-small cell lung cancer.
Exosomes derived from human umbilical cord mesenchymal stem cells alleviate Parkinson's disease and neuronal damage through inhibition of microglia.
Single-cell dissection of cellular and molecular features underlying mesenchymal stem cell therapy in ischemic acute kidney injury.
PACS-2 deficiency aggravates tubular injury in diabetic kidney disease by inhibiting ER-phagy.
Urinary exosome proteins PAK6 and EGFR as noninvasive diagnostic biomarkers of diabetic nephropathy.
Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy.
Manganese regulation of COPII condensation controls circulating lipid homeostasis.
CYP26B1-related disorder: expanding the ends of the spectrum through clinical and molecular evidence.
Prognostic and immunological role of cancer-associated fibroblasts-derived exosomal protein in esophageal squamous cell carcinoma.
Heterozygous variants c.781G>A and c.1066dup of serine protease 56 cause familial nanophthalmos by impairing serine-type endopeptidase activity.
Role of a holo-insertase complex in the biogenesis of biophysically diverse ER membrane proteins.
Extracellular Vesicles and Their Renin-Angiotensin Cargo as a Link between Metabolic Syndrome and Parkinson's Disease.
STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons.
Lymphocyte migration regulation related proteins in urine exosomes may serve as a potential biomarker for lung cancer diagnosis.
PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation.
ASTER-B regulates mitochondrial carotenoid transport and homeostasis.
Mesenchymal stem cells ameliorate cisplatin-induced acute kidney injury via let-7b-5p.
Plasma exosome-derived circGAPVD1 as a potential diagnostic marker for colorectal cancer.
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
M2 Macrophage-Derived sEV Regulate Pro-Inflammatory CCR2(+) Macrophage Subpopulations to Favor Post-AMI Cardiac Repair.
Testicular exosomes disturb the immunosuppressive phenotype of testicular macrophages mediated by miR-155-5p in uropathogenic Escherichia coli-induced orchitis.
ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer.
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Extracellular vesicle-mediated delivery of anti-miR-106b inhibits morphine-induced primary ciliogenesis in the brain.
Stress Granules Inhibit Coxsackievirus B3-Mediated Cell Death via Reduction of Mitochondrial Reactive Oxygen Species and Viral Extracellular Release.
CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation.
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Extracellular Vesicles Released from Macrophages Infected with Mycoplasma pneumoniae Stimulate Proinflammatory Response via the TLR2-NF-κB/JNK Signaling Pathway.
SERS spectroscopy with machine learning to analyze human plasma derived sEVs for coronary artery disease diagnosis and prognosis.
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
Proteomic Characterization of Peritoneal Extracellular Vesicles in a Mouse Model of Peritoneal Fibrosis.
p130Cas is required for androgen-dependent postnatal development regulation of submandibular glands.
Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps.
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Tanshinone IIA enhances the therapeutic efficacy of mesenchymal stem cells derived exosomes in myocardial ischemia/reperfusion injury via up-regulating miR-223-5p.
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
Exosomal microRNA‑4516, microRNA‑203 and SFRP1 are potential biomarkers of acute myocardial infarction.
Circulating extracellular vesicles from patients with traumatic brain injury induce cerebrovascular endothelial dysfunction.
miR-142-3p encapsulated in T lymphocyte-derived tissue small extracellular vesicles induces Treg function defect and thyrocyte destruction in Hashimoto's thyroiditis.
Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury.
TMEM41B Is an Interferon-Stimulated Gene That Promotes Pseudorabies Virus Replication.
Lipid nanoparticle delivery of siRNA targeting Cyp2e1 gene attenuates subacute alcoholic liver injury in mice.
ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies.
Extracellular vesicle-packaged ILK from mesothelial cells promotes fibroblast activation in peritoneal fibrosis.
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts.
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Two microRNAs of plasma-derived small extracellular vesicles as biomarkers for metastatic non-small cell lung cancer.
Changes in urinary exosomal protein CALM1 may serve as an early noninvasive biomarker for diagnosing diabetic kidney disease.
Extracellular Vesicles from Carcinoma-associated Fibroblasts Promote EMT of Salivary Adenoid Cystic Carcinoma Via IL-6.
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions.
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
Low-intensity pulsed ultrasound (LIPUS) enhances the anti-inflammatory effects of bone marrow mesenchymal stem cells (BMSCs)-derived extracellular vesicles.
miR-150-5p in neutrophil-derived extracellular vesicles associated with sepsis-induced cardiomyopathy in septic patients.
A RIPK3-independent role of MLKL in suppressing parthanatos promotes immune evasion in hepatocellular carcinoma.
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.
Mesenchymal stem cells-derived exosomes ameliorate high glucose and lipopolysaccharide-induced HPMECs injury through the Nrf2/HO-1 pathway.
Integrated transcriptomics, proteomics, and functional analysis to characterize the tissue-specific small extracellular vesicle network of breast cancer.
Negatively charged bladder acellular matrix loaded with positively charged adipose-derived mesenchymal stem cell-derived small extracellular vesicles for bladder tissue engineering.
SARS-CoV-2 papain-like protease plays multiple roles in regulating cellular proteins in the endoplasmic reticulum.
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism.
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10.
Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization.
Extracellular vesicles long RNA profiling identifies abundant mRNA, circRNA and lncRNA in human bile as potential biomarkers for cancer diagnosis.
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
MiR-146b-5p enriched bioinspired exosomes derived from fucoidan-directed induction mesenchymal stem cells protect chondrocytes in osteoarthritis by targeting TRAF6.
ARRDC5 deficiency impairs spermatogenesis by affecting SUN5 and NDC1.
Cultured lymphocytes' mitochondrial genome integrity is not altered by cladribine.
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.
Engineered Extracellular Vesicle-Based Therapies for Valvular Heart Disease.
The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity.
Tumor-Associated Extracellular Microvesicles with Fluorine-Modified Carbohydrate Antigens Trigger a Stronger Antitumor Immune Response.
Carcinoma-associated fibroblast-derived lysyl oxidase-rich extracellular vesicles mediate collagen crosslinking and promote epithelial-mesenchymal transition via p-FAK/p-paxillin/YAP signaling.
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
ARF6 plays a general role in targeting palmitoylated proteins from the Golgi to the plasma membrane.
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Exosomes incorporated with black phosphorus quantum dots attenuate retinal angiogenesis via disrupting glucose metabolism.
MicroRNA-19b-3p dysfunction of mesenchymal stem cell-derived exosomes from patients with abdominal aortic aneurysm impairs therapeutic efficacy.
Pharmacological chaperones restore proteostasis of epilepsy-associated GABA(A) receptor variants.
Pigmentation and TYRP1 expression are mediated by zinc through the early secretory pathway-resident ZNT proteins.
Phenylethanoid glycosides extract from Cistanche deserticola ameliorates atherosclerosis in apolipoprotein E-deficient mice and regulates intestinal PPARγ-LXRα-ABCA1 pathway.
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Signal-Retaining Autophagy Indicator as a Quantitative Imaging Method for ER-Phagy.
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.
miR-29a-3p in Exosomes from Heme Oxygenase-1 Modified Bone Marrow Mesenchymal Stem Cells Alleviates Steatotic Liver Ischemia-Reperfusion Injury in Rats by Suppressing Ferroptosis via Iron Responsive Element Binding Protein 2.
Intraneuronal sortilin aggregation relative to granulovacuolar degeneration, tau pathogenesis and sorfra plaque formation in human hippocampal formation.
The potential role of exosomal miRNAs and membrane proteins in acute HIV-infected people.
Extracellular Vesicle-Mediated Delivery of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles to Mice Brain.
Characterization and subcellular localization of Alongshan virus proteins.
Exosomal CD44 Transmits Lymph Node Metastatic Capacity Between Gastric Cancer Cells via YAP-CPT1A-Mediated FAO Reprogramming.
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Hypoxic Cell-Derived Extracellular Vesicles Aggravate Rectal Injury Following Radiotherapy via MiR-122-5p.
The activity of disease-causative STING variants can be suppressed by wild-type STING through heterocomplex formation.
Phospholipid peroxidation inhibits autophagy via stimulating the delipidation of oxidized LC3-PE.
Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.
De novo sphingolipid biosynthesis necessitates detoxification in cancer cells.
TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.
TMEΜ45B Interacts with Sindbis Virus Nsp1 and Nsp4 and Inhibits Viral Replication.
TMEM63C mutations cause mitochondrial morphology defects and underlie hereditary spastic paraplegia.
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Aberrant Cholesterol Metabolism and Wnt/β-Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth.
The role of hepatic Surf4 in lipoprotein metabolism and the development of atherosclerosis in apoE(-/-) mice.
The delivery of miR-21a-5p by extracellular vesicles induces microglial polarization via the STAT3 pathway following hypoxia-ischemia in neonatal mice.
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.
Mutated lncRNA increase the risk of type 2 diabetes by promoting β cell dysfunction and insulin resistance.
Extracellular vesicles derived from endometrial epithelial cells deliver exogenous miR-92b-3p to affect the function of embryonic trophoblast cells via targeting TSC1 and DKK3.
Extracellular Vesicles Secreted by Mouse Decidual Cells Carry Critical Information for the Establishment of Pregnancy.
Proteomic and miRNA Profiles of Exosomes Derived from Myometrial Tissue in Laboring Women.
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.
Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.
SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection.
Extracellular vesicles from human urine-derived stem cells merged in hyaluronic acid ameliorate erectile dysfunction in type 2 diabetic rats by glans administration.
Plasma Extracellular Vesicle Long RNA in Diagnosis and Prediction in Small Cell Lung Cancer.
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1.
Extracellular vesicle-derived long non-coding RNA as circulating biomarkers for endometriosis.
The endoplasmic reticulum adopts two distinct tubule forms.
Autophagic LC3(+) calcified extracellular vesicles initiate cartilage calcification in osteoarthritis.
Evaluation of plasma exosomal miRNAs as potential diagnostic biomarkers of lymph node metastasis in papillary thyroid carcinoma.
Photobiomodulation promotes hair regeneration in injured skin by enhancing migration and exosome secretion of dermal papilla cells.
Human Cytomegalovirus Hijacks WD Repeat Domain 11 for Virion Assembly Compartment Formation and Virion Morphogenesis.
ESCRT dysfunction compromises endoplasmic reticulum maturation and autophagosome biogenesis in Drosophila.
ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.
N-terminome analyses underscore the prevalence of SPPL3-mediated intramembrane proteolysis among Golgi-resident enzymes and its role in Golgi enzyme secretion.
MOSPD2 is an endoplasmic reticulum-lipid droplet tether functioning in LD homeostasis.
Preparation of Recombinant Human Collagen III Protein Hydrogels with Sustained Release of Extracellular Vesicles for Skin Wound Healing.
Micro-RNAs from Plasma-Derived Small Extracellular Vesicles as Potential Biomarkers for Tic Disorders Diagnosis.
Exosomal tRF-Leu-AAG-001 derived from mast cell as a potential non-invasive diagnostic biomarker for endometriosis.
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation.
FAM69C, a kinase critical for synaptic function and memory, is defective in neurodegenerative dementia.
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice.
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
Inflammatory capacity of exosomes released in the early stages of acute pancreatitis predicts the severity of the disease.
Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases.
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.
Golgi phosphoprotein 3 promotes angiogenesis and sorafenib resistance in hepatocellular carcinoma via upregulating exosomal miR-494-3p.
Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via M2 macrophages.
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.
Splicing factor arginine/serine-rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome-based cellular communication.
Plasma extracellular vesicle microRNA profiling and the identification of a diagnostic signature for stage I lung adenocarcinoma.
Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.
Atrophic skeletal muscle fibre-derived small extracellular vesicle miR-690 inhibits satellite cell differentiation during ageing.
Circ-CREBBP inhibits sperm apoptosis via the PI3K-Akt signaling pathway by sponging miR-10384 and miR-143-3p.
Identification of Circulating Exosomal microRNAs Associated with Radioiodine Refractory in Papillary Thyroid Carcinoma.
Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.
Exosomes from the Uterine Cavity Mediate Immune Dysregulation via Inhibiting the JNK Signal Pathway in Endometriosis.
A cryostat-based frozen section method to increase the yield of extracellular vesicles extracted from different tissues.
Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.
Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency.
Differential proteomic analysis of plasma-derived exosomes as diagnostic biomarkers for chronic HBV-related liver disease.
Tumor-promoting mechanisms of macrophage-derived extracellular vesicles-enclosed microRNA-660 in breast cancer progression.
Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway.
Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells.
miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia-reperfusion injury in steatotic grafts.
VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion.
Autophagy-Based Unconventional Secretory for AIM2 Inflammasome Drives DNA Damage Resistance During Intervertebral Disc Degeneration.
MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.
Identification of the Association Between Toll-Like Receptors and T-Cell Activation in Takayasu's Arteritis.
GATA4-driven miR-206-3p signatures control orofacial bone development by regulating osteogenic and osteoclastic activity.
LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.
SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.
Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds.
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Neuronal Exosomes Secreted under Oxygen-Glucose Deprivation/Reperfusion Presenting Differentially Expressed miRNAs and Affecting Neuronal Survival and Neurite Outgrowth.
Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1.
Differential Expression Pattern of Goat Uterine Fluids Extracellular Vesicles miRNAs during Peri-Implantation.
Hemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence.
Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.
Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation.
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Hypercholesterolemia risk associated Abca6 does not regulate lipoprotein metabolism in mice or hamster.
Comparison of MicroRNA Profiles in Extracellular Vesicles from Small and Large Goat Follicular Fluid.
hnRNPA2B1-Mediated Extracellular Vesicles Sorting of miR-122-5p Potentially Promotes Lung Cancer Progression.
AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway.
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins.
The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry.
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι.
A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation.
Identification of exosome miRNAs in bronchial epithelial cells after PM2.5 chronic exposure.
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Secretome of Activated Fibroblasts Induced by Exosomes for the Discovery of Biomarkers in Non-Small Cell Lung Cancer.
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Small RNA-seq analysis of extracellular vesicles from porcine uterine flushing fluids during peri-implantation.
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
GBA Mutations Influence the Release and Pathological Effects of Small Extracellular Vesicles from Fibroblasts of Patients with Parkinson's Disease.
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Thromboangiitis obliterans plasma-derived exosomal miR-223-5p inhibits cell viability and promotes cell apoptosis of human vascular smooth muscle cells by targeting VCAM1.
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Japanese encephalitis virus manipulates lysosomes membrane for RNA replication and utilizes autophagy components for intracellular growth.
Use of four genes in exosomes as biomarkers for the identification of lung adenocarcinoma and lung squamous cell carcinoma.
STING regulates BCR signaling in normal and malignant B cells.
Adipose-derived stem cell exosomes facilitate rotator cuff repair by mediating tendon-derived stem cells.
Extracellular-vesicle containing miRNA-503-5p released by macrophages contributes to atherosclerosis.
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage.
Mechanism of Sanguinarine in Inhibiting Macrophages to Promote Metastasis and Proliferation of Lung Cancer via Modulating the Exosomes in A549 Cells.
Enrichment of CD44 in Exosomes From Breast Cancer Cells Treated With Doxorubicin Promotes Chemoresistance.
Proteomic Profiling of Serum Exosomes From Patients With Metastatic Gastric Cancer.
GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice.
Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.
Insight into the proteomic profiling of exosomes secreted by human OM-MSCs reveals a new potential therapy.
Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging.
Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Oncoprotein SND1 hijacks nascent MHC-I heavy chain to ER-associated degradation, leading to impaired CD8(+) T cell response in tumor.
Exosomal long non-coding RNA MSTRG.292666.16 is associated with osimertinib (AZD9291) resistance in non-small cell lung cancer.
HPV + HNSCC-derived exosomal miR-9 induces macrophage M1 polarization and increases tumor radiosensitivity.
Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.
Characterization of serum small extracellular vesicles and their small RNA contents across humans, rats, and mice.
APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin.
Design of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling.
The protective effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on cisplatin-damaged granulosa cells.
Three-dimensional culture of dental pulp pluripotent-like stem cells (DPPSCs) enhances Nanog expression and provides a serum-free condition for exosome isolation.
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.
Polyethylene Glycol 35 (PEG35) Modulates Exosomal Uptake and Function.
Mycobacterium tuberculosis MmsA (Rv0753c) Interacts with STING and Blunts the Type I Interferon Response.
SCYL1 arginine methylation by PRMT1 is essential for neurite outgrowth via Golgi morphogenesis.
USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy.
Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress.
Identification of Lipid Droplet Proteomes by Proximity Labeling Proteomics Using APEX2.
Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation.
Proteomic analysis of seminal extracellular vesicle proteins involved in asthenozoospermia by iTRAQ.
Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress.
Protective effect of Barbaloin in a rat model of myocardial ischemia reperfusion injury through the regulation of the CNPY2‑PERK pathway.
Peri-Infarct Upregulation of the Oxytocin Receptor in Vascular Dementia.
Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection.
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
Two novel ANK1 loss-of-function mutations in Chinese families with hereditary spherocytosis.
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
Zika Virus Subverts Stress Granules To Promote and Restrict Viral Gene Expression.
Microglia as modulators of exosomal alpha-synuclein transmission.
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway.
Adipocyte-Derived Exosomes Carrying Sonic Hedgehog Mediate M1 Macrophage Polarization-Induced Insulin Resistance via Ptch and PI3K Pathways.
Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling.
Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway.
In Vivo Tracking of Multiple Tumor Exosomes Labeled by Phospholipid-Based Bioorthogonal Conjugation.
Enhanced MiR-711 transcription by PPARγ induces endoplasmic reticulum stress-mediated apoptosis targeting calnexin in rat cardiomyocytes after myocardial infarction.
Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.
Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.
A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.
A RAB27A 5' untranslated region structural variant associated with late-onset hemophagocytic lymphohistiocytosis and normal pigmentation.
The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.
A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Protein kinase D at the Golgi controls NLRP3 inflammasome activation.
Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis.
Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.
Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion.
REG3β modifies cell tumor function by impairing extracellular vesicle uptake.
Dominant ER Stress-Inducing WFS1 Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts.
DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.
Involvement of exosomes in lung inflammation associated with experimental acute pancreatitis.
Quantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells.
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector.
Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancer.
Development of a mitochondria-based centrifugal ultrafiltration/liquid chromatography/mass spectrometry method for screening mitochondria-targeted bioactive constituents from complex matrixes: Herbal medicines as a case study.
Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.
IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection.
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3.
PolyC-binding protein 1 interacts with 5'-untranslated region of enterovirus 71 RNA in membrane-associated complex to facilitate viral replication.
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.
Rab18 and a Rab18 GEF complex are required for normal ER structure.
Reduced expression of members of the mhc-i antigen processing machinery in ethnic Uighur women with cervical cancer in the Xinjiang region of China.
ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.
Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis.
Ke Y, Wang Y
Stem cells international 2026;2026:3606738
Stem cells international 2026;2026:3606738
A panel of serum-derived exosomal miRNAs as markers of cardiovascular risk assessed by carotid intima-media thickness in patients with type 2 diabetes.
Lu W, Yin L, Zou S, Wu M, Du X, Li H, Shi B
American journal of translational research 2026;18(1):236-247
American journal of translational research 2026;18(1):236-247
Seminal plasma extracellular vesicle-derived miR-296-3p targets PLA2G6 to enhance boar sperm motility by lowering Lys Phosphatidylcholine.
Zhao K, An Y, Zhang Y, Zhang J, Li H, Wang J, Yao Z, Wang T, Chen L, Chen X, Jin Y
Animal reproduction science 2026 May;288:108135
Animal reproduction science 2026 May;288:108135
Atrophic Skeletal Muscle-Derived Extracellular Vesicles Transfer miR-125a-5p to Inhibit Bone Formation in Osteoporosis during Aging.
Shao X, Zhang P, Fan Z, Lin J, Chen X, Liu N, Gong W, He Y, Zhou Y, Shi T, Shi Y, Ma Y, Gao W, Wang H, Fang D, Wang C, Wu W, Yan W, Qin J, Chen D, Yu H, Jiang Q, Guo B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e15362
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e15362
TEAD1 Enhances Exosome Secretion and Promotes Exosome-Mediated Tissue Regeneration.
Pu Y, Wan Y, Shi W, Li B, Zhang H, Wu J, Li L, Guo W, Ding C, Yang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e14104
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e14104
Ectopic endometrial mesenchymal stem cell-derived exosomal miR-4466 promotes angiogenesis by targeting RUNX1 in adenomyosis.
Wang J, Ni Y, Sun J, Qiu Y, Wei X, Wang B, Huang M, Li Z, Gui T
Biochemistry and biophysics reports 2026 Mar;45:102457
Biochemistry and biophysics reports 2026 Mar;45:102457
A GluN2B disease-associated variant promotes the degradation of NMDA receptors via autophagy.
Benske TM, Williams MP, Zhang PP, Palumbo AJ, Mu TW
The Journal of biological chemistry 2026 Mar;302(3):111147
The Journal of biological chemistry 2026 Mar;302(3):111147
CCPG1-mediated reticulophagy promotes tumorigenesis and cisplatin resistance in bladder cancer.
Dong Y, Tian S, Peng X, Wang P, Qian X, Xie C, Tu R, Wang X, Cui Y
Autophagy 2026 Mar;22(3):586-602
Autophagy 2026 Mar;22(3):586-602
Establishment of a simple and novel method for contact-dependent intercellular interaction analysis using extracellular vesicles.
Sakamaki R, Matsuba T, Kurihara Y
Journal of bioscience and bioengineering 2026 Mar;141(3):194-202
Journal of bioscience and bioengineering 2026 Mar;141(3):194-202
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Xie X, Bi S, Su B, Zhou R, Li X, Yan Z, Zhou X, Wang F, Yu T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
Canine Adipose MSC-Derived Exosomes Ameliorate Skeletal Muscle Injury in Mice.
Gao J, Li Y, Zhong Y
Animals : an open access journal from MDPI 2026 Mar 9;16(5)
Animals : an open access journal from MDPI 2026 Mar 9;16(5)
TRIM27-controlled endothelium-derived exosomes play a central role in podocyte injury in diabetic kidney disease.
Tian Y, Liu Y, Feng X, Wu L, Song W, Zhao T, Liu J, Miao X, Ma H, Jia B, Kang L, Liu Q, Zhang W, Guo H, Yang L, Xu J, Liu S
Cell death discovery 2026 Mar 7;12(1)
Cell death discovery 2026 Mar 7;12(1)
Red Blood Cell-Derived Exosomes Deliver Complement C5 to Exacerbate Neuroinflammation and Neuronal Injury after Intracerebral Hemorrhage.
Chen Q, Min J, Lu X, Gao Z, Xiong Y
Inflammation 2026 Mar 5;49(1)
Inflammation 2026 Mar 5;49(1)
Natural photosynthetic system for restoring homeostasis of animal organelle interaction network.
Xia C, Dai Z, Wang Y, Yu J, Wang Z, Huang Z, Pan K, Yang K, Chen Y, Zhong P, Gu C, Fan S, Lin X, Chen P
Nature communications 2026 Mar 31;17(1)
Nature communications 2026 Mar 31;17(1)
Complement 5a receptor 2 attenuates diabetic kidney disease by promoting mitochondria-associated endoplasmic reticulum membrane formation mediated by PSS-MFN2 interaction.
Zhao YY, Wang YH, Li ZH, Chang DY, Nie L, Zhao MH, Tang SCW, Chen M
Cell discovery 2026 Mar 31;12(1)
Cell discovery 2026 Mar 31;12(1)
Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs-STAT3 Pathway.
Dai B, Wang S, Peng X, Wu K, Wu M, Lu Z, Zhong H, Qian X, Tan S, Yang H, Sun T, Wang J, Zhang J, Jiang H, Tong Y, Chen T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 31;:e02791
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 31;:e02791
Glycosylated NS3/NS3A protein of bluetongue virus facilitates efficient viral egress via lipid raft anchoring.
Huang Y, Qi Y, Guan J, Shao R, Xi C, Liu X, Zhou D, Qi S, Yin X
Journal of virology 2026 Mar 24;100(3):e0214425
Journal of virology 2026 Mar 24;100(3):e0214425
A dual role for ER-Golgi cargo receptor LMAN1 in supporting CSFV replication and restraining RLR signaling.
Han K, Chang Z, Li N, Xiao D, Song M, Wang T, Guo K, Zhang L, Deng W
Journal of virology 2026 Mar 24;100(3):e0006926
Journal of virology 2026 Mar 24;100(3):e0006926
Extracellular vesicles derived from live or apoptotic mesenchymal stem cells: comparison of the effects of two extracellular vesicles on liver fibrosis.
Ju R, Tian S, Li B, Zhang M, Ma S, Hu Y, Su R, Yang F, Xia E, Shang Y, Zhou X, Han Y
BMC gastroenterology 2026 Mar 23;26(1)
BMC gastroenterology 2026 Mar 23;26(1)
Heat stress suppresses lactation through potential rumen-mammary communication mediated by extracellular vesicles: integrated analysis of microbiome, metabolome, and miRNA profiles.
Huang Q, Du D, Guo J, Liu J, Sun P
Microbiome 2026 Mar 17;14(1)
Microbiome 2026 Mar 17;14(1)
GDF15-Treated iPSC-MSC-Derived Exosomes Alleviate Fibrosis Post-Myocardial Infarction via Repression of the MFAP4/ERK/Drp1 Axis.
Qiu J, Han Q, Shen Y, Yang Q, Li Z, Hong Y, Zhao J, Lin F, Ma K, Hu B, Liang X, Zhang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 15;40(5):e71621
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 15;40(5):e71621
Control of lysosome function by the GTPase-activating protein TBC1D9B and its binding partner TMEM55B.
Duhay V, Tian M, Kosieradzka K, Ebner M, Lo WT, Krauss M, Sprengel HL, Voss M, Riechmann M, Savas JN, Schwake M, Haucke V, Damme M
Nature communications 2026 Mar 14;17(1)
Nature communications 2026 Mar 14;17(1)
Collagen-Bearing Exosomes from Breast Cancer-Associated Fibroblasts Promote T-cell Dysfunction.
Jana S, Lawton M, Lei PJ, Hui H, Emili A, Jones D
Cancer research communications 2026 Mar 1;6(3):630-647
Cancer research communications 2026 Mar 1;6(3):630-647
Lung cancer cell-derived exosomal EHF drives M2 macrophage polarization via transcriptional activation of RNF41 to promote tumor progression.
Chen Z, Ying J, Huang G, Shang W, Shi K, Wang Z, Wang L, Ding D, Zhang C, Tan Y
Regenerative therapy 2026 Jun;32:101104
Regenerative therapy 2026 Jun;32:101104
Mechanisms and therapeutic strategies of BiP-HSPA9 axis-mediated endoplasmic reticulum-mitochondria crosstalk driven by bile acids in gastric intestinal metaplasia.
He Q, Chen N, Gong S, Xu S, Song Y, Li P, Yu H, Liu Y, Jiang K, Zhao J
Free radical biology & medicine 2026 Jun;249:195-210
Free radical biology & medicine 2026 Jun;249:195-210
Urinary exosomes aggravate diabetic kidney disease by inducing podocyte ferroptosis via the miR-217/SIRT1/Nrf2 pathway.
Du X, Jiang Y, Guo H, Zhang H, Wang S, Deng H, Huang X, Li X
Journal of cell communication and signaling 2026 Jun;20:e70076
Journal of cell communication and signaling 2026 Jun;20:e70076
Hepatocyte specific Rab27a knockout aggravates metabolic dysfunction associated fatty liver disease.
Hu JY, Liao XY, Ran RZ, Lu TT, Lin Y, Wang MW, Lin MJ, Liang X, Yang MQ
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168223
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168223
Ellagic acid alleviates ulcerative colitis in a GPR35-dependent manner associated with SDH restoration.
Xiang K, Wang P, Liu Y, Chen Y, Liu D, Han Y, Shen A, Xu F, Yu W, Wei L, Piao HL, Fang Y, Wang J, Liang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158130
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158130
Plasma exosomal proteomics: Unveiling novel biomarkers for ischemic stroke in the context of diabetes.
Jiang Q, Peng G, Kong Q, Zhou Y, Zhao H, Geng X
Brain research bulletin 2026 Jun 1;239:111884
Brain research bulletin 2026 Jun 1;239:111884
Microenvironment-educated MSC-EVs loaded injectable smart hydrogel for targeting senescent nucleus pulposus cells and inhibiting ferroptosis against intervertebral disc degeneration.
Wu W, Cheng Z, Shi P, Gao H, Chen X, Wu W, Yu Z, Yang C, Zhang Y
Bioactive materials 2026 Jul;61:555-576
Bioactive materials 2026 Jul;61:555-576
PAM-assembled CRISPR-Cas12a activation-based fluorescent and colorimetric dual-modal biosensor for detecting prostate cancer exosomes.
Miao Y, Wang C, Peng Y, Sun X, Zheng Z, Zhang Q, Cheng W, Li J
Biosensors & bioelectronics 2026 Jul 15;304:118635
Biosensors & bioelectronics 2026 Jul 15;304:118635
A Natural LDHA Allosteric Inhibitor Geraniin Suppresses Triple-Negative Breast Cancer Cell Growth.
Yu Y, Ye X, Hou T, Zhou H, Liu L, Yuan W, Wang J, Liang X
Phytotherapy research : PTR 2026 Jan;40(1):21-34
Phytotherapy research : PTR 2026 Jan;40(1):21-34
TAMs-derived exosomes promote breast cancer progression by regulating the IRF9/IFI6 axis.
Zhao X, Wang Y, Yang X, Guo H
Breast cancer (Tokyo, Japan) 2026 Jan;33(1):164-177
Breast cancer (Tokyo, Japan) 2026 Jan;33(1):164-177
Melatonin-engineered MSCs-exosomes deliver USP4 to stabilise ARNTL and inhibit clock rhythmic ferroptosis for enhanced flap survival.
Jiang X, Wang Y, Zhang X, Deng H, Fang L, Tafadzwa C, Yao J, Chen H, Ye A, Zhou K, Ling X, Xiao J
Clinical and translational medicine 2026 Jan;16(1):e70565
Clinical and translational medicine 2026 Jan;16(1):e70565
Circular RNA-based HPV16 therapeutic vaccine elicits potent and durable antitumor immunity.
Zhou R, Li C, Xiang K, Cui L, Rong Y, Li L, Zhu M, Zeng J, Gao L
Journal of experimental & clinical cancer research : CR 2026 Jan 7;45(1):33
Journal of experimental & clinical cancer research : CR 2026 Jan 7;45(1):33
Ferroptosis-dependent small extracellular vesicles ULK1 enhances mitophagy and suppresses breast cancer migration.
Wang A, Chen M, Luo Y, Li L, Rong J, Liu L, Yi C
Hereditas 2026 Jan 26;163(1):30
Hereditas 2026 Jan 26;163(1):30
MYC-driven TRIM27 upregulation promotes prostate cancer progression by enhancing CANX ubiquitination and activating PI3K/AKT signaling.
Wang Z, Ning J, Xu L, Cheng F
Functional & integrative genomics 2026 Jan 20;26(1):29
Functional & integrative genomics 2026 Jan 20;26(1):29
Neuroprotective Effects of Desert Milk Exosomes in LPS-Induced Cognitive Decline: Role of Microglial M2 Polarization and AMPK Signaling.
Li Y, Lu W, Qian W, Liao X, Wang P, Wang Y, Jiao W, Wang M, Zhao J, Yang J, Gao H, Li H
Nutrients 2026 Jan 19;18(2)
Nutrients 2026 Jan 19;18(2)
Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis.
Arunagiri A, Haataja L, Alam M, Gleason NF, Mastroianni E, Cheng CY, Bazzi S, Knupp J, Metawea I, Hassan A, Larkin D, Fang D, Tsai B, Qi L, Arvan P
The Journal of clinical investigation 2026 Jan 16;136(2)
The Journal of clinical investigation 2026 Jan 16;136(2)
Immunological conversion of triple-negative breast cancer by engineered extracellular vesicle-mediated pyroptosis.
Zhang H, Sun M, Chen J, Wang S, Liu J, Yang H, Liu L, Hu S, Yang F, Teng L, Chen Z, Wang X, Dong S, Ma Y, Edwards JL, Wang X, Chang YT, Kim BYS, Jiang W, Cui Y, Yang Z
Journal of controlled release : official journal of the Controlled Release Society 2026 Jan 10;389:114493
Journal of controlled release : official journal of the Controlled Release Society 2026 Jan 10;389:114493
Citicoline Triggers Proteome Remodeling and Proteostatic Adaptation: Evidence from Shotgun Proteomics.
Cavaterra D, Giammaria S, Pandino I, Zingale GA, Delli Paoli V, Fiore R, Michelessi M, Roberti G, Carnevale C, Tanga L, Cazzato D, Peroni E, Grasso G, Manni G, Bocedi A, Oddone F, Coletta M, Sbardella D, Tundo GR
Pharmaceutics 2026 Jan 1;18(1)
Pharmaceutics 2026 Jan 1;18(1)
GSTP1-modified exosomes derived from ADMSCs relieve LPS-induced acute lung injury.
Guan H, Du J, Wang X, Zhang Z, Zhou W, Wang F
Cytotechnology 2026 Feb;78(1):9
Cytotechnology 2026 Feb;78(1):9
Unconventional Secretion of Angiogenic Sonic Hedgehog-Containing Extra-Large Extracellular Vesicles is Driven by PI3K-Rab18-GDP Signalling.
Wang S, Imai R, Kaneko Y, Tanaka Y
Journal of extracellular biology 2026 Feb;5(2):e70112
Journal of extracellular biology 2026 Feb;5(2):e70112
E3 ligase AREL1 controls perinuclear localization of lysosomes and supports Purkinje cell survival.
Jiang L, Tang J, Zhang YF, Zou WX, Deng G, Tian N, Zhao X, Han L, Liu K, Song BL, Luo J
The EMBO journal 2026 Feb;45(3):655-691
The EMBO journal 2026 Feb;45(3):655-691
Proteomics of Prostate Cancer Tissue Small Extracellular Vesicles Reveal Alteration of Metabolism.
Yu L, Ding T, Olofsson Bagge R, Zheng L, Hao X
Proteomics 2026 Feb;26(2-3):121-128
Proteomics 2026 Feb;26(2-3):121-128
Decreased PTGES2 Farnesylation in Granulosa Cells Compromises PGE2-Dependent Cumulus Expansion and Oocyte Maturation During Ovarian Aging.
Zhang S, Qi J, Liu C, Zhang H, Guo B, Wu D, Liu Y, Zhen X, Zhang Y, Kang N, Zhou J, Yan G, Li C, Ding L, Sun H
Aging cell 2026 Feb;25(2):e70374
Aging cell 2026 Feb;25(2):e70374
Multifunctional extracellular vesicles inhibiting autophagy ameliorate immunotherapy in non-small cell lung cancer.
Wang S, Chen J, Cui Y, Xing J, Liu J, Jiang H, Yang H, Zhang H, Sun M, Li J, Liu W, Chen Z, Sun W, Wang X, Yang Z
Acta pharmaceutica Sinica. B 2026 Feb;16(2):1022-1045
Acta pharmaceutica Sinica. B 2026 Feb;16(2):1022-1045
SNRPC promotes chemoresistance in Wilms tumor via the NF-κB-CXCL17 axis regulating M2-Type TAMs infiltration and targeted nanotherapy research.
Kong X, Lei L, Jin L, Ren C, Mi T, Wang Q, He D
Journal of experimental & clinical cancer research : CR 2026 Feb 28;45(1)
Journal of experimental & clinical cancer research : CR 2026 Feb 28;45(1)
Neural stem cell-derived exosomal PA2G4 induces ANXA2 degradation to promote mitophagy and alleviate neuronal oxidative stress in cerebral ischemia/reperfusion.
Dai M, Lu T, Li J, Yu H
Apoptosis : an international journal on programmed cell death 2026 Feb 20;31(3)
Apoptosis : an international journal on programmed cell death 2026 Feb 20;31(3)
Acutely denervated muscle EVs reshape neuronal mitochondrial metabolism via retrograde signaling to rescue peripheral nerve injury.
Liu Q, Xue B, Zhang Y, Qin M, Zhu Z, Wang Z, Li H, Fan S, Su M, Li S, Yang S, Qin A, Ma T, Gao X, Sun H, Hao Y, Guo L, Nie S, Wang J, Luo Z, Huang J, Xia B
Cell reports. Medicine 2026 Feb 17;7(2):102585
Cell reports. Medicine 2026 Feb 17;7(2):102585
Comprehensive analysis of tissue-derived small extracellular vesicles transcriptomic and extensively targeted lipidomics from patients with high-grade serous ovarian cancer.
Fu M, Wang J, Wu H, Peng P, Cao D
BMC cancer 2026 Feb 13;26(1)
BMC cancer 2026 Feb 13;26(1)
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
Zhang Z, Shen H, Zhang S, Zhou J, Zhang M, Wang Y, Zheng Y, Chang Y, Liang X, Hu X, Gao W
International immunopharmacology 2026 Feb 1;170:116077
International immunopharmacology 2026 Feb 1;170:116077
CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis.
Wu L, Wang J, Wang Y, Yang J, Yao Y, Wang Y, Huang D, Hu Y, Xu X, Wang R, Du W, Shi Y, Li Q, Liu L, Zhu Y, Li S, Chen FJ, Zhang X, Wang X, Guo Q, Xu L, Li P, Chen XW
Nature 2026 Apr;652(8109):471-480
Nature 2026 Apr;652(8109):471-480
POSTN(+) fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling.
Zhang C, Chen S, Qian C, Lv W, Zhang Q, Wang Y, Wu Y, Liu X
Oncology reports 2026 Apr;55(4)
Oncology reports 2026 Apr;55(4)
STARD3 regulates lysosome positioning and contacts via a GSK3-controlled phosphorylation switch.
Eichler J, Wendling C, Huver S, Zouiouich M, Hanss V, Cardinal A, Fimbel V, Birck C, McEwen AG, Knorr C, Fromental-Ramain C, Boutry M, Chenard MP, Drin G, Tomasetto C, Alpy F
The EMBO journal 2026 Apr;45(7):2239-2277
The EMBO journal 2026 Apr;45(7):2239-2277
Umbilical cord mesenchymal stem cells and their extracellular vesicles attenuate cryopreservation-induced ovarian injury via the suppression of ferroptosis in an in vitro culture system.
Xu W, Yao X, Chen C, Wang M, Chen Y, Liang D, Gao Q, Wang X, Zhou P, Wang J
Materials today. Bio 2026 Apr;37:102965
Materials today. Bio 2026 Apr;37:102965
Viperin inhibits coronavirus replication by targeting non-structural protein 8 to disrupt replication-transcription complex assembly and RNA-dependent RNA polymerase activity.
Li J, Wang Q, Du L, Chen H, Hu J, Zhou Y, Peng Q, Shi Y, Zhou J, Gu J
International journal of biological macromolecules 2026 Apr;359:151843
International journal of biological macromolecules 2026 Apr;359:151843
Mutant PLP1 impairs COPII vesicle formation via ER calcium depletion in Pelizaeus-Merzbacher disease.
Li H, Mishima R, Goto YI, Inoue K
Neurobiology of disease 2026 Apr;221:107329
Neurobiology of disease 2026 Apr;221:107329
Ascites circRNA ASCOR Drives Platinum Resistance of High-Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation.
Liu H, Zhu C, Yao X, Liu Y, Zhu J, Li Y, Xu H, Peng C, Shan G, Chen L, Zhou Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e18922
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e18922
EMCV Non-Structural Protein 2C Antagonizes cGAS-STING-Mediated Type I Interferon Signaling via Promoting K48-Linked Polyubiquitination and Degradation of STING.
Cheng R, Dong P, Xing W, Jin H, Ma T, Xie J, Wen Y, Su B, Li X, Feng R
Viruses 2026 Apr 5;18(4)
Viruses 2026 Apr 5;18(4)
MiR-423-5p inhibition alleviates podocyte apoptosis in membranous nephropathy by targeting WT1/β-catenin axis.
Liu H, Zhang S, Zhao XN, Wang ZZ, Song JN, Liu SX
International urology and nephrology 2026 Apr 4;
International urology and nephrology 2026 Apr 4;
Mesenchymal stem cells derived EXO-miR3671 delivery promoted angiogenesis and accelerated wound healing of diabetes.
Li J, Chen S, Wang H, Wang W, Liu Y
Stem cells (Dayton, Ohio) 2026 Apr 25;44(5)
Stem cells (Dayton, Ohio) 2026 Apr 25;44(5)
Disruption of spike protein N-glycosylation induces its endoplasmic reticulum retention and attenuates SARS-CoV-2 infectivity.
Kong W, Zhang J, Song Y, Song J, Xu Y, Xu X, Ma H, Chen L, Zeng C
Journal of virology 2026 Apr 21;100(4):e0027026
Journal of virology 2026 Apr 21;100(4):e0027026
Efficient hybridoma screening using extracellular vesicles for conformation-specific antibodies to transmembrane proteins.
Sakamaki R, Matsuba T, Kurihara Y
Journal of bioscience and bioengineering 2026 Apr 18;
Journal of bioscience and bioengineering 2026 Apr 18;
Exosomal miR-92b-5p regulates N4BP1 to enhance PTEN mono-ubiquitination in doxorubicin-resistant AML.
Li Q, Cheng J, Qin D, Xiao S, Yao C
Cancer drug resistance (Alhambra, Calif.) 2025;8:16
Cancer drug resistance (Alhambra, Calif.) 2025;8:16
A single-sEV analysis identifies plasma EPCAM(+) sEVs as a biomarker for early diagnosis and monitoring postoperative remission of thyroid cancer.
Yu S, Luo Y, Dang T, Peng C, Gan Q, Liang Y, Yu J, Long P, Zhou W, Dai D
Extracellular vesicles and circulating nucleic acids 2025;6(4):982-999
Extracellular vesicles and circulating nucleic acids 2025;6(4):982-999
Engineered Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Mitigate Liver Fibrosis by Delivering USP10 to Reprogram Macrophage Phenotype.
Tian S, Zhou X, Zheng L, Liu J, Zhang M, Ma S, Zheng X, Guo G, Ju R, Yang F, Liu Y, Li B, Hu Y, Xia E, Su R, Sun K, Cui L, Guo C, Zhou X, Wang J, Shang Y, Han Y
Biomaterials research 2025;29:0244
Biomaterials research 2025;29:0244
Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.
Zhou Z, Wu S, Li Y, Shao P, Jiang J
Biomaterials research 2025;29:0220
Biomaterials research 2025;29:0220
Overexpression of miRNA-216 in exosomes derived from umbilical cord mesenchymal stem cells promotes angiogenesis and improves functional recovery after spinal cord injury.
Li H, Yi R, Fan Y, Zhan G, Xiao T
Iranian journal of basic medical sciences 2025;28(10):1344-1353
Iranian journal of basic medical sciences 2025;28(10):1344-1353
Immunological Safety Evaluation of Exosomes Derived From Human Umbilical Cord Mesenchymal Stem Cells in Mice.
Wang C, Hu X, Liu Y, Xiao Y, Jiang P, Lin Y, Liu X, Zhang Z, Li LC, Qi Z
Stem cells international 2025;2025:9986368
Stem cells international 2025;2025:9986368
Extracellular Vesicles Derived from FGF2-Primed Astrocytes Against Mitochondrial and Synaptic Toxicities in Parkinson's Disease.
Wen X, Cao W, Ding H, Chen A, Sun Z, Wang Y, Xi Y, Wu S
International journal of nanomedicine 2025;20:4627-4644
International journal of nanomedicine 2025;20:4627-4644
Plasma-derived exosomal miRNAs as potentially novel biomarkers for type 2 diabetes mellitus with abdominal obesity.
Li Y, Wang Y, Li Z, Feng L, Feng R, Jia J, Xing L, Zheng L
Frontiers in endocrinology 2025;16:1656132
Frontiers in endocrinology 2025;16:1656132
Engineered NK92 cell-derived exosomes inhibit ovarian cancer progression by degrading GPRC5A.
Si C, Wang Y, Li Y, Chen Y, Fan Y, Wang Y, Tian Y, Gao J, Ma X
Frontiers in immunology 2025;16:1613178
Frontiers in immunology 2025;16:1613178
Development of a prognostic model for hepatocellular carcinoma based on microvascular invasion characteristic genes by spatial transcriptomics sequencing.
Mu X, Pan L, Wang X, Liu C, Li Y, Cai Y, He Z
Frontiers in immunology 2025;16:1529569
Frontiers in immunology 2025;16:1529569
An anti-FAP-scFv-functionalized exosome-carrying hydrogel delivers SKI mRNA to fibrotic nucleus pulposus cells to alleviate intervertebral disc degeneration by regulating FOXO3.
Li Y, Zhai Y, Wang T, Wang S, Tian Y, Bian Z, Zhang Y, Zhang C, Liu M, Li C
Theranostics 2025;15(9):3877-3899
Theranostics 2025;15(9):3877-3899
A novel pathway for stemness propagation and chemoresistance in non-small cell lung cancer via phosphorylated PKM2-loaded small extracellular vesicles.
Wang J, Liu L, Gao X, Liu X, Dai Y, Mao Z, Huang S, Li J, Wang D, Qi Y, Han Y, Xu Y, Chua CYX, Grattoni A, Xie W, Yang H, Huang G
Theranostics 2025;15(8):3439-3461
Theranostics 2025;15(8):3439-3461
Pharmacological targeting of mitophagy via ALT001 improves herpes simplex virus 1 (HSV1)-mediated microglial inflammation and promotes amyloid β phagocytosis by restricting HSV1 infection.
Oh SJ, Kim YY, Ma R, Choi ST, Choi SM, Cho JH, Hur JY, Yoo Y, Han K, Park H, Yun J, Shin OS
Theranostics 2025;15(11):4890-4908
Theranostics 2025;15(11):4890-4908
M1 macrophage-derived exosomal miR-20b promotes radiosensitization via CCND1 in HPV(+) HNSCC.
Liu H, Zhang S, Liu Z, Gong T, Duan S, Liu T, Tong F, Li W, Pan S, Wei L
Frontiers in oncology 2025;15:1693487
Frontiers in oncology 2025;15:1693487
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
Ren X, Wang Z, Wang J, Li X, Wei H, Liu C, Liu S, Zhu Y, Feng C, Yin Y, Tian Y, Wu M, Zeng X
ImmunoTargets and therapy 2025;14:151-173
ImmunoTargets and therapy 2025;14:151-173
Chaetoglobosin A induces apoptosis in T-24 human bladder cancer cells through oxidative stress and MAPK/PI3K-AKT-mTOR pathway.
Song J, Qiao J, Chen M, Li J, Wang J, Yu D, Zheng H, Shi L
PeerJ 2025;13:e19085
PeerJ 2025;13:e19085
Exosomes derived from miR-26a-5p-modified adipose mesenchymal stem cells improve wound healing by targeting MAP2K4.
Chen K, Ye W, Chi L, Xie S
Frontiers in bioengineering and biotechnology 2025;13:1662095
Frontiers in bioengineering and biotechnology 2025;13:1662095
Curcumin-primed milk-derived extracellular vesicles remodel hair follicle microenvironment for the treatment of androgenetic alopecia.
Hou C, Wang S, Li Z, Huang Q, Jiang Y, Zhou X, Ou R, Li D, Xu Y
Regenerative biomaterials 2025;12:rbaf051
Regenerative biomaterials 2025;12:rbaf051
Development of serum glycosylated exosomal microRNAs as biomarkers for early diagnosis of lung adenocarcinoma.
Huang Z, Chen J, Gao Q, Hao K, Yu C, Huang Y
Frontiers in medicine 2025;12:1695874
Frontiers in medicine 2025;12:1695874
EMAP-II from macrophage-derived extracellular vesicles drives neutrophil extracellular traps formation via PI3K/AKT/mtROS in lung ischemia/reperfusion injury.
Zhuang H, Song X, Li J, Li Z, Wu S, Wang P, Shen H, He X, Guo Y, Li Z, Lin F
Redox biology 2025 Sep;85:103750
Redox biology 2025 Sep;85:103750
Exosome-derived lnc-FAM72D-3 promotes lenvatinib resistance by remodeling hepatocellular carcinoma cytoskeleton via MBNL1/FAK axis.
Cao M, Li Y, Su X, Tang Y, Ren Y, Luo J, Yuan F, Yang G, He Z, Shi Z, Hu Z, Liang G, Zhang Q, Deng M, Yao Z, Lin N
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Sep;82:101271
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Sep;82:101271
M2 Macrophages-Derived Exosomes Inhibited Podocyte Pyroptosis via lncRNA AFAP1-AS1/EZH2 Axis.
Zhan Q, Liu H, Zhao M, Huang H
Clinical and experimental pharmacology & physiology 2025 Sep;52(9):e70056
Clinical and experimental pharmacology & physiology 2025 Sep;52(9):e70056
3D-printed advanced scaffold armed with exosomes derived from human skeletal stem cell identified by single-cell RNA sequencing enhances osteochondral regeneration.
Lou W, Qiu X, Qin Y, Lu Y, Cao Y, Lu H
Bioactive materials 2025 Sep;51:231-256
Bioactive materials 2025 Sep;51:231-256
Glyphosate targets FYN to regulate glycolysis and promote glioblastoma proliferation: A network toxicology study.
Ma A, Yang Z, He Q, Wang W, Ren H, Zhai C, Lan J
International journal of biological macromolecules 2025 Sep;321(Pt 3):146486
International journal of biological macromolecules 2025 Sep;321(Pt 3):146486
Endometrial Mesenchymal Stem Cell-Derived Exosomal miR-4669 Promotes EMT in Adenomyosis by Inducing M2 Macrophage Polarization via the DUSP6/ERK Pathway.
Qiu Y, Wei X, Cao J, Wang J, Dou Q, Zhou F, Chen X, Liu Y, Wan G, Huang M, Li Z, Gui T
Reproductive sciences (Thousand Oaks, Calif.) 2025 Sep;32(9):2922-2945
Reproductive sciences (Thousand Oaks, Calif.) 2025 Sep;32(9):2922-2945
Disulfide bond-mediated stabilization of the oligomers of UDP-glucuronosyltransferase 2B7.
Miyauchi Y, Koba H, Sawai M, Kansui H, Takechi S, Hishinuma E, Matsukawa N, Hiratsuka M, Mackenzie PI, Ishii Y
The Journal of biological chemistry 2025 Sep;301(9):110502
The Journal of biological chemistry 2025 Sep;301(9):110502
IAV NS1 carried by exosomes promotes IL-10 production by the PI3K-AKT-GSK3β-CREB pathway.
Huang HM, Yang HH, Qin YC, Luo JY, Jiang ZS, Zhang ZR, Ning LJ, Li L, Wu Y
Microbial pathogenesis 2025 Sep;206:107777
Microbial pathogenesis 2025 Sep;206:107777
Multidimensional Engineering of Extracellular Vesicles for Targeted Delivery and Microglial Reprograming in Spinal Cord Injury Repair.
Xiong W, Liu M, Wang J, Liu J, Zheng M, Chan P, Zhu Q, Li C, Kong G, Tang C, Fan J
ACS nano 2025 Sep 9;19(35):31551-31571
ACS nano 2025 Sep 9;19(35):31551-31571
MiR-7683-3p from M2-exosomes attenuated atherosclerosis by activating the PPARγ-LXRα-ABCG1 pathway mediated cholesterol efflux of vascular smooth muscle cell derived foam cells.
Wang S, Lv Y, Wang X, Zhang Z, Li J, Pan TI, Yung MAC, Zhang F, Zhang H, Meng J, Lian H, Wen S, Hao X, Wang P, Zhang Q, He T, Zhang Y, Wang X, Song J, Cui Y
Journal of nanobiotechnology 2025 Sep 29;23(1):618
Journal of nanobiotechnology 2025 Sep 29;23(1):618
MSCs-EXOs containing miR-21a-5p promoted cell proliferation in the rat retinal Müller cell rMC-1 via targeting LATS1.
Deng L, Wang Y
Stem cell research & therapy 2025 Sep 29;16(1):529
Stem cell research & therapy 2025 Sep 29;16(1):529
Comprehensive multiomic analysis of extracellular vesicles from Mycoplasma bovis-infected bovine mammary epithelial cells identifies proteins and miRNAs that induce inflammatory responses in macrophages.
Wu Y, Yuan X, Ma J, Xu L, Li M, Zhao G, Wang Y
Veterinary research 2025 Sep 25;56(1):185
Veterinary research 2025 Sep 25;56(1):185
Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia.
Liu X, Li R, Sun J, Yang Y, Hu L
European journal of histochemistry : EJH 2025 Sep 22;69(4)
European journal of histochemistry : EJH 2025 Sep 22;69(4)
Exosomes from small intestinal epithelium mediate cardiac fibrosis during aging.
He Y, Lu X, Pang S, Xia F, Lv Y, Yu J, Ding G, Sheng Y
The journals of gerontology. Series A, Biological sciences and medical sciences 2025 Sep 19;80(10)
The journals of gerontology. Series A, Biological sciences and medical sciences 2025 Sep 19;80(10)
Ellagic Acid-Loaded sEVs Encapsulated in GelMA Hydrogel Accelerate Diabetic Wound Healing by Activating EGFR on Skin Repair Cells.
Tian L, Wang Z, Chen S, Guo K, Hao Y, Ma L, Ma K, Chen J, Liu X, Li L, Fu X, Zhang C
Cell proliferation 2025 Oct;58(10):e70064
Cell proliferation 2025 Oct;58(10):e70064
AntagomiR-192-5p-engineered exosomes encapsulated in MXene-modified GelMA hydrogel facilitated epithelization of burn wounds by targeting OLFM4.
Liu W, Huang H, Shu F, Liu Y, Lin J, Yang L, Zhang W, Jiang L, Liu T, Xie C, Li L, He Y, Xiao S, Zheng Y, Xia Z
Bioactive materials 2025 Oct;52:318-337
Bioactive materials 2025 Oct;52:318-337
Mevalonate metabolites boost aged oocyte quality through prenylation of small GTPases.
Liu C, Zhang H, Mao J, Zhang S, Tian X, Zhu Y, Wang C, Fang J, Pan H, Kang N, Zhang Y, Zhou J, Zhen X, Yan G, Li C, Hu Y, Ye C, Xie R, So C, Sun H, Ding L
Nature aging 2025 Oct;5(10):2022-2038
Nature aging 2025 Oct;5(10):2022-2038
Umbilical cord blood-derived exosomes deliver miR-182-5p to Therapeutically target the MYD88/NF-κB signaling pathway in rat peri-implantitis.
Liu H, Zhu D, Lang L, Liu M, Yang Z, Zhang Z, Shen Z
Materials today. Bio 2025 Oct;34:102246
Materials today. Bio 2025 Oct;34:102246
Suppression of SREBP by a transmembrane protein mutated in cardiomyopathy.
Takemoto Y, Tserendagva M, Uesugi M
The Journal of biological chemistry 2025 Oct;301(10):110644
The Journal of biological chemistry 2025 Oct;301(10):110644
The exosomal miRNA-3184-3p derived from highly metastatic melanoma cells promotes metastatic competency via the positive feedback loop of NLK/Wnt/S100A11.
Chen Y, Zeng B, Xiang M, Han X, Zhang X, Chen H, Zhao Q, Liu D, Li X, Li J, Zhang Y, Shi L, Li B, Chen Y, Tang Y, Li J, Xing HR, Wang J
Biochemical pharmacology 2025 Oct;240:117086
Biochemical pharmacology 2025 Oct;240:117086
ATP2A2 regulates STING1/MITA-driven signal transduction including selective autophagy.
Yang X, Lv L, Zhang Y, Zhang Z, Zeng S, Zhang X, Wang Q, Dorf M, Li S, Fu B
Autophagy 2025 Oct;21(10):2230-2245
Autophagy 2025 Oct;21(10):2230-2245
Urinary extracellular vesicle RNAs as novel biomarkers for diagnosis and prognosis of lupus nephritis.
Zhang H, Zheng X, Huang S, Qian L, Wu J, Shi Z, Jia M, Bai Y, Jiang L, Jia S, Zen K, Yuan Y, Liang J, Liang H
Clinical kidney journal 2025 Oct;18(10):sfaf295
Clinical kidney journal 2025 Oct;18(10):sfaf295
Exosome-derived hsa_circ_0007132 promotes lenvatinib resistance by inhibiting the ubiquitin-mediated degradation of NONO.
Cao M, Li Y, Su X, Tang Y, Yuan F, Ren Y, Deng M, Yao Z
Non-coding RNA research 2025 Oct;14:1-13
Non-coding RNA research 2025 Oct;14:1-13
Exosomal miR-382-5p prevents pre-metastatic niche formation by inhibiting GPR176/GNAS-CXCR1/CXCR2 axis in colorectal cancer liver metastasis.
Yang L, Zhu H, Chen L, Zhang J, Huang J, Zeng L, Zong Z
Cellular signalling 2025 Oct;134:111963
Cellular signalling 2025 Oct;134:111963
POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?
Liu H, Li X, Li M, Sun Z, Wang X, Li J, Xu B, Chen Q, Fan C, Ruan H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e07951
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e07951
Exosome-Based Proteomic Profiling for Biomarker Discovery in Pediatric Fabry Disease: Insights into Early Diagnosis Monitoring.
Lu Z, Xia Y, Wang B, Jiang P, Mao J
Biomedicines 2025 Oct 23;13(11)
Biomedicines 2025 Oct 23;13(11)
Exosomal miR-122-5p from tubular cells ameliorates renal interstitial fibrosis by regulating fibroblasts via HIF-1α.
Yang J, Bai F, Li Y, Gao Q, Li L, Zeng Z, Jia J, Jia N, Zhang Y, Gao Y, Zhang H
Cell death discovery 2025 Oct 21;11(1):474
Cell death discovery 2025 Oct 21;11(1):474
Pak4-mediated crosstalk between necroptotic macrophages and tendon stem/progenitor cells contributes to traumatic heterotopic ossification formation.
Sun Z, Liu H, Xu Y, Chen Q, Luo G, Yuan Z, Chen Z, He K, Fan C, Li J, Ruan H
Bone research 2025 Oct 20;13(1):88
Bone research 2025 Oct 20;13(1):88
Extracellular vesicles derived from menstrual blood-derived mesenchymal stem cells suppress inflammatory atherosclerosis by inhibiting NF-κB signaling.
Yu J, Liu X, Jin L, Li H, Wang S, Yang Y, Chen X, Wang H, Li Y, Lian J, Shi C, Li H, Zhang Y, Moses EJ, Zhang H, Zheng C, Zhu X
BMC medicine 2025 Oct 15;23(1):565
BMC medicine 2025 Oct 15;23(1):565
The APOE ε4 allele affects the survival of patients with Parkinson's disease independent of dementia.
Wang Z, Li L, Xu Q, Pan H, Wang Y, Long Q, Huang Y, Dai Y, Zhang S, Zhou Q, Zhao G, Li B, Tang B, Qiu J, Li J
Journal of translational medicine 2025 Oct 14;23(1):1094
Journal of translational medicine 2025 Oct 14;23(1):1094
Bta-miR-199a-3p in embryonic bovine lung cells-derived extracellular vesicles enhances pro-inflammatory cytokine expression in macrophages via DUSP5 upregulation during Mycoplasma bovis infection.
He J, Guo Y, Wang Y, Zhao G
International immunopharmacology 2025 Oct 10;163:115252
International immunopharmacology 2025 Oct 10;163:115252
The significance of urine extracellular vesicle DNA methylation detection in the diagnosis and classification of prostate cancer.
Ding T, Diao Y, Fu R, Gong C, He Q, He W, Zhang L, Yang X, Zeng X, Yu L, Liu J, Shi W, Zhang K, Hao X
Journal of advanced research 2025 Oct 1;
Journal of advanced research 2025 Oct 1;
Dual-targeting exosome vaccine confers efficient protection against CVB3-induced myocarditis.
Cao Q, Ge Y, Wang T, Lin K, Xiong S, Yue Y
Nanomedicine : nanotechnology, biology, and medicine 2025 Nov;70:102865
Nanomedicine : nanotechnology, biology, and medicine 2025 Nov;70:102865
RAB22A triggers intercellular chemoresistance transmission in colorectal cancer by promoting exosome release via the PKM2-pSNAP23 axis.
Yin Y, Ming L, Qin Y, Tang J, Liu B, Liu Y, Jin G, Jiang L, Yao S, Qi X, Huang Z
Oncogene 2025 Nov;44(43):4205-4217
Oncogene 2025 Nov;44(43):4205-4217
M2 Macrophage-Derived Migrasomes Mediate Ischaemia-Induced Retinal Neovascularization by Targeting TREM2.
Li B, Chen J, Zhu J, Zhou H, Zhang Q, Deng H, Wen H, Xu F, Tang F, Yoshida S, Zhou Y
Journal of extracellular vesicles 2025 Nov;14(11):e70180
Journal of extracellular vesicles 2025 Nov;14(11):e70180
Gastric cancer-derived exosomal miR-196a-5p remodels the pre-metastatic niche for peritoneal dissemination.
Zhang Z, Wang M, Gao X, Tai G, Li F, Wang Z
Cellular signalling 2025 Nov;135:112039
Cellular signalling 2025 Nov;135:112039
Glabridin-Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity.
Wang Z, Wang M, Chen Q, Wang M, Li F, Lv L, Wen Z, Xu Z, Yang Y, Bi C, Liu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e04729
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e04729
Serum exosomal lncRNA LINC00472 combined with serum CK-MB and cTnI as diagnostic biomarker for acute myocardial infarction.
Zuo Y
Heart & lung : the journal of critical care 2025 Nov-Dec;74:96-103
Heart & lung : the journal of critical care 2025 Nov-Dec;74:96-103
Mfn2 Regulates Scleral Remodeling in Myopia by Maintaining Endoplasmic Reticulum Homeostasis in Scleral Fibroblasts.
Wang Y, Liu S, Huang Q, Cheng Y
Investigative ophthalmology & visual science 2025 Nov 3;66(14):40
Investigative ophthalmology & visual science 2025 Nov 3;66(14):40
Antihypertension and Improvement Effects of Hexapeptide APPLRP on Exosomes-Mediated Vascular Endothelial Inflammation in Spontaneously Hypertensive Rats.
Cai Q, Zhang T, Zhai K, Guo B, Gong Q, Yang Y, Ding YY, Gu Z, Song T
Journal of agricultural and food chemistry 2025 Nov 26;73(47):30458-30472
Journal of agricultural and food chemistry 2025 Nov 26;73(47):30458-30472
Study on the Mechanism of Acanthopanax senticosus Extract Intervening in the Regulation of Parkinson's Disease by BV2 Microglial Cell-Derived Exosomes.
Lu N, Wang Y, Lu Y, Lu F, Liu S
Molecular neurobiology 2025 Nov 24;63(1):159
Molecular neurobiology 2025 Nov 24;63(1):159
Extracellular vesicle derived miRNAs from plasma as promising diagnosis and prognosis biomarkers for neuroblastoma.
Zhou D, Wang Y, Zhu M, Li L, Peng J, Hu Y, Xiong J, Tao T, Wang J, Zhao Z
iScience 2025 Nov 21;28(11):113636
iScience 2025 Nov 21;28(11):113636
Fusobacterium nucleatum-derived extracellular vesicles carrying virulence factor DNA trigger AIM2 inflammasome activation to facilitate UC progression.
Zhao Y, Wu R, Duan Y, Kong X, Zhang Y, You Y, Zhang J, Wang Y, Zhou L, Duan L
Cellular & molecular biology letters 2025 Nov 17;30(1):138
Cellular & molecular biology letters 2025 Nov 17;30(1):138
Epigenetic silencing of MSTN via m6A modification underlies the renoprotective effects of engineered MSC exosomes with RBM15 depletion in diabetic nephropathy.
Dong Q, Dong L, Zhu Y, Wang X, Yan X
Functional & integrative genomics 2025 Nov 17;25(1):244
Functional & integrative genomics 2025 Nov 17;25(1):244
Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Transfer CD59 to Astrocytes to Alleviate Complement-Dependent Cytotoxicity.
Shen Q, Wang X, Ou Q, Wang Q, Zhao Z, Chen Z, Zhu X, Li D, Jin C, Gao F, Wang J, Lu L, Bi Y, Wan W, Guan Y, Xu GT, Xu JY, Tian H
Molecular neurobiology 2025 Nov 14;63(1):41
Molecular neurobiology 2025 Nov 14;63(1):41
Characteristics of extracellular vesicle-derived lncRNAs during the progression of HBV-related hepatocellular carcinoma.
Ma Y, Lou C, Liang J, Guo C, Zhang J, Lu C, Zhang J, Gao Y
BMC cancer 2025 Nov 14;25(1):1768
BMC cancer 2025 Nov 14;25(1):1768
Construction of a prognostic model for nasopharyngeal carcinoma based on serum exosomal circular RNAs and analysis of immune microenvironment.
Feng HJ, Liang S, Wang DT, Xu SE, Qin G
Clinical and experimental medicine 2025 Nov 11;25(1):370
Clinical and experimental medicine 2025 Nov 11;25(1):370
MiR-519d-3p from Placenta-Derived Exosomes Induce Immune Intolerance Regulating Immune Cells, Contributing to the Pathogenesis of Preeclampsia.
Cao SQ, Jiang TX, Guo YY, Lin R, Lin L
Immunological investigations 2025 May;54(4):522-543
Immunological investigations 2025 May;54(4):522-543
Exosomes Derived From BMMSCs Promote B10 Cell Differentiation but Not IL-10 Production.
Wang J, Gu Y, Wang J, Zhang N, Han X, Bai Y
Cell biochemistry and function 2025 May;43(5):e70083
Cell biochemistry and function 2025 May;43(5):e70083
Lipid droplets restrict phagosome formation in antifungal immunity.
Sun W, Wu H, Zhao G, Shui Q, Zhang L, Luan X, Chen T, Liu F, Zheng Y, Zhao W, Qi X, Liu B, Gao C
Cellular & molecular immunology 2025 May;22(5):468-484
Cellular & molecular immunology 2025 May;22(5):468-484
The ER protein CANX (calnexin)-mediated autophagy protects against alzheimer disease.
Shen H, Xie Y, Wang Y, Xie Y, Wang Y, Su Z, Zhao L, Yao S, Cao X, Liang J, Long J, Zhong R, Tang J, Wang S, Zhang L, Wang X, Stork B, Cui L, Wu W
Autophagy 2025 May;21(5):1096-1115
Autophagy 2025 May;21(5):1096-1115
Targeting capacity, safety and efficacy of engineered extracellular vesicles delivered by transdermal microneedles to treat plasmacytoma in mice.
Cao Y, Hu X, Wu D, Jiang Y, Yu Y, Wang S, Chen W, Long Y, Xu L, Qu J, Yang B, Chakhabi B, Wang H, Deng Y, Chen L, Chen Z, Li Q
Clinical and translational medicine 2025 May;15(5):e70327
Clinical and translational medicine 2025 May;15(5):e70327
Syntaxin 17 Translocation Mediated Mitophagy Switching Drives Hyperglycemia-Induced Vascular Injury.
Luo A, Wang R, Gong J, Wang S, Yun C, Chen Z, Jiang Y, Liu X, Dai H, Liu H, Zheng Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2414960
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2414960
HucMSCs-Derived Extracellular Vesicles Deliver RPS27A Protein to Manipulate the MDM2-P53 Axis and Ameliorate Neurological Dysfunction in Parkinson's Disease.
Xu J, Lei H, Yang C, Qiu Y, Wu X
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 May 8;20(1):52
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 May 8;20(1):52
Extracellular vesicles derived from bone marrow mesenchymal stem cells regulate SREBF2/HMGB1 axis by transporting miR-378a-3p to inhibit ferroptosis in intestinal ischemia-reperfusion injury.
Liu Z, Zhao Z, Xiao Z, Li M, Wang X, Huang Y, Li Y
Cell death discovery 2025 May 7;11(1):223
Cell death discovery 2025 May 7;11(1):223
Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response.
Wang Z, Guo W, Zhang X, Wei Y, Zhang W, Du N, Li C, Wu X, Yi F, Zhou T, Dong X, Guo Q, Xu H, Wang E, Li N, Cheng R, Li Z, Song X, Sun Y, Sun X, Cao L
Cell reports 2025 May 27;44(5):115679
Cell reports 2025 May 27;44(5):115679
Exosomal miR-432-5p, miR-4433b-5p, and miR-599: Biomarkers for Monitoring the Severity of Anti-N-methyl-D-aspartate Receptor Encephalitis.
Xie Z, Liu L, Guo Y, Jiang H, Li L, Qiao Z, Wang J
Journal of integrative neuroscience 2025 May 27;24(5):37513
Journal of integrative neuroscience 2025 May 27;24(5):37513
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma.
Ma T, Guo WW, Zhang M, He W, Dongzhi C, Gongye X, Xia P, Chai Y, Chen Z, Zhu Y, Qu C, Liu J, Yang Z, Ma W, Tian M, Yuan Y
Cell death & disease 2025 May 15;16(1):382
Cell death & disease 2025 May 15;16(1):382
Chaihu-Shugan-San alleviates post-stroke depression in mice: Mechanistic insights into exosome-mediated neuroprotection.
Wu Q, Xie Z, Cao X, Hu D, Sheng L, Guo X, Yan D, Ding C, Li C, Xiao J, Liu C, Wu K, Gong Y, Fan Q, Wang Q, Liu J, Liu Y
Journal of ethnopharmacology 2025 May 12;347:119700
Journal of ethnopharmacology 2025 May 12;347:119700
Evaluating the feasibility of gene replacement strategies to treat MTRFR deficiency.
Pratt SL, Zarate-Mendez M, Koludarova L, Jansson S, Airavaara M, Hlushchuk I, Coleman D, Heffner C, Horvath R, Battersby BJ, Burgess RW
Disease models & mechanisms 2025 May 1;18(5)
Disease models & mechanisms 2025 May 1;18(5)
AKAP1/PKA-mediated GRP75 phosphorylation at mitochondria-associated endoplasmic reticulum membranes protects cancer cells against ferroptosis.
Liu H, Zheng S, Hou G, Dai J, Zhao Y, Yang F, Xiang Z, Zhang W, Wang X, Gong Y, Li L, Zhang N, Hu Y
Cell death and differentiation 2025 Mar;32(3):488-505
Cell death and differentiation 2025 Mar;32(3):488-505
Aggregated proinsulin in pancreatic β-cells is degraded by the autophagy pathway.
Madey YF, Syed SK, Van Horn RD, Pineros AR, Efanov AM
The Journal of biological chemistry 2025 Mar;301(3):108257
The Journal of biological chemistry 2025 Mar;301(3):108257
Exosomal miR-184 facilitates bladder cancer progression by targeting AKR1C3 and inducing immune escape via IRF2-CXCL10 axis.
Ying W, Zhao Y, He Y, Deng Y, Gan X, Li P, Chen X, Ding Z
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167627
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167627
Inducible global knockout of surfeit locus protein 4 in adult mice results in hypolipidemia, intestinal lipid accumulation, liver injury, and increased mortality.
Chen W, Chen Y, Song B, Zhai L, Tao G, Wang B, Liu B, Wang H, Zhang CX, Gu HM, Yin D, Qin S, Zhang DW
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Mar;1870(2):159577
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Mar;1870(2):159577
Extracellular vesicle-packaged PKM2 from endometriotic stromal cells promotes endometrial collagen I deposition by inhibiting autophagy in endometriosis.
Zhu Y, Gao L, Zhang J, Li M, Zhou J, Zhou J
Cellular signalling 2025 Mar;127:111523
Cellular signalling 2025 Mar;127:111523
Extracellular vesicular delivery of ceramides from pulmonary macrophages to endothelial cells facilitates chronic obstructive pulmonary disease.
Huang Q, Kang T, Shen S, Liu L, Zhang L, Zou X, Wu J
Cell communication and signaling : CCS 2025 Mar 7;23(1):124
Cell communication and signaling : CCS 2025 Mar 7;23(1):124
Extracellular vesicles derived from mesenchymal stem cells ameliorate sulfur mustard-induced lung injury by regulating apoptosis via miR-146a-5p.
Pei Z, Sun Y, Zhang S, Gong C, Mao G, Zhang X, Meng W, Cen J, Li S, Sun M, Xu Q, Xiao K
International immunopharmacology 2025 Mar 26;150:114285
International immunopharmacology 2025 Mar 26;150:114285
STT3B promotes porcine epidemic diarrhea virus replication by regulating N-glycosylation of PEDV S protein.
Zhu H, Lou J, Yang Z, Bai J, Jiang P, Wang X, Liu X
Journal of virology 2025 Mar 18;99(3):e0001825
Journal of virology 2025 Mar 18;99(3):e0001825
Organelle-tuning condition robustly fabricates energetic mitochondria for cartilage regeneration.
Chen X, Zhou Y, Yao W, Gao C, Sha Z, Yi J, Wang J, Liu X, Dai C, Zhang Y, Wu Z, Yao X, Zhou J, Liu H, Chen Y, Ouyang H
Bone research 2025 Mar 17;13(1):37
Bone research 2025 Mar 17;13(1):37
Exosomes containing miR-152-3p targeting FGFR3 mediate SLC7A7-induced angiogenesis in bladder cancer.
Cao C, Wang Y, Deng X, Zhao X, Chen Y, Tan W, Deng F, Li F
NPJ precision oncology 2025 Mar 12;9(1):71
NPJ precision oncology 2025 Mar 12;9(1):71
Static Topographical Cue Combined with Dynamic Fluid Stimulation Enhances the Macrophage Extracellular Vesicle Yield and Therapeutic Potential for Bone Defects.
Huang H, Xiao L, Fang L, Lei M, Liu Z, Gao S, Lei Q, Lei J, Wei R, Lei Y, Xue L, Geng Z, Cai L, Yan F
ACS nano 2025 Mar 11;19(9):8667-8691
ACS nano 2025 Mar 11;19(9):8667-8691
Mannose-modified exosomes loaded with MiR-23b-3p target alveolar macrophages to alleviate acute lung injury in Sepsis.
Lin J, Yang L, Liu T, Zhao H, Liu Y, Shu F, Huang H, Liu W, Zhang W, Jiang L, Xiao S, Zheng Y, Xia Z
Journal of controlled release : official journal of the Controlled Release Society 2025 Mar 10;379:832-847
Journal of controlled release : official journal of the Controlled Release Society 2025 Mar 10;379:832-847
E-jet 3D printed aligned nerve guidance conduits incorporated with decellularized extracellular matrix hydrogel encapsulating extracellular vesicles for peripheral nerve repair.
Fan N, Song D, Ding H, Yang H, Xu C, Wang C, Yang Y
Acta biomaterialia 2025 Mar 1;194:122-139
Acta biomaterialia 2025 Mar 1;194:122-139
Multifunctional magneto-electric and exosome-loaded hydrogel enhances neuronal differentiation and immunoregulation through remote non-invasive electrical stimulation for neurological recovery after spinal cord injury.
Liu W, Liu Q, Li Z, Zhang C, Li Z, Ke H, Xu X, Wang X, Du H, Talifu Z, Pan Y, Wang X, Mao J, Gao F, Yang D, Yu Y, Liu X, Li J
Bioactive materials 2025 Jun;48:510-528
Bioactive materials 2025 Jun;48:510-528
Exosomal miR-196a-5p Secreted by Bone Marrow Mesenchymal Stem Cells Inhibits Ferroptosis and Promotes Drug Resistance of Acute Myeloid Leukemia.
Fan B, Wang L, Hu T, Zheng L, Wang J
Antioxidants & redox signaling 2025 Jun;42(16-18):933-953
Antioxidants & redox signaling 2025 Jun;42(16-18):933-953
Engineered Extracellular Vesicles Loaded with MiR-100-5p Antagonist Selectively Target the Lesioned Region to Promote Recovery from Brain Damage.
Cheng Y, Gai C, Zhao Y, Li T, Song Y, Luo Q, Xin D, Jiang Z, Chen W, Liu D, Wang Z
Neuroscience bulletin 2025 Jun;41(6):1021-1040
Neuroscience bulletin 2025 Jun;41(6):1021-1040
Antimicrobial dual-crosslinked hydrogel synergizes bioengineered extracellular vesicles for enhanced diabetic wound healing.
Ju Y, Yang P, Liu X, Wu R, Shen N, Hsiung N, Yang A, Zhang C, Fang B, Liu L
Materials today. Bio 2025 Jun;32:101870
Materials today. Bio 2025 Jun;32:101870
Endoscopic nasal delivery of engineered endothelial progenitor cell-derived exosomes improves angiogenesis and neurological deficits in rats with intracerebral hemorrhage.
Wan G, Li Z, Gu L, Sun Y, Wang Y, Wang Y, Geng R, Chen Y, Ma W, Bao X, Wang R
Materials today. Bio 2025 Jun;32:101652
Materials today. Bio 2025 Jun;32:101652
Charge-reversed small extracellular vesicles from human adipose-derived mesenchymal stromal cells attenuate renal fibrosis postacute kidney injury by inhibiting epithelial-mesenchymal transition progression in SD rat model.
Ping W, Xu X, Jiang Y, Yang R, Xu L
Cytotherapy 2025 Jun;27(6):753-765
Cytotherapy 2025 Jun;27(6):753-765
Senescent cartilage endplate stem cells-derived exosomes induce oxidative stress injury in nucleus pulposus cells and aggravate intervertebral disc degeneration by regulating FOXO3.
Bian Z, Zhai Y, Zhang Y, Wang T, Li H, Ouyang J, Liu C, Wang S, Hu Z, Chang X, Zhang C, Liu M, Li C
Free radical biology & medicine 2025 Jun;233:39-54
Free radical biology & medicine 2025 Jun;233:39-54
Macrophages-derived small extracellular vesicles regulate chondrocyte proliferation and affect osteoarthritis progression via upregulating Osteopontin expression.
Tu M, Liu AM, Huang W, Wang D, Chen HQ, Hu XY
Journal of cell communication and signaling 2025 Jun;19(2):e70008
Journal of cell communication and signaling 2025 Jun;19(2):e70008
Targeting RPSA to modulate endosomal trafficking and amyloidogenesis in genetic Alzheimer's disease.
Limone A, Di Napoli C, Napolitano F, Imbò B, Minopoli G, Bagnoli S, Izzo A, Paladino S, Nacmias B, De Matteis MA, Montuori N, Lavecchia A, Sarnataro D
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167753
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167753
YTHDF1 differentiates the contributing roles of mTORC1 in aging.
Xu C, Yu C, Zhang J, Zhang Z, Zhang J, Meng Y, Wang M, Wen M, Chen J, Ning Y, Chen X, Gu J, Su W, Liu B
Molecular cell 2025 Jun 5;85(11):2194-2210.e8
Molecular cell 2025 Jun 5;85(11):2194-2210.e8
Brain-derived exosomal hemoglobin transfer contributes to neuronal mitochondrial homeostasis under hypoxia.
Tian Z, Li Y, Jin F, Xu Z, Gu Y, Guo M, Shao Q, Liu Y, Luo H, Wang Y, Zhang S, Yang C, Liu X, Ji X, Liu J
eLife 2025 Jun 23;13
eLife 2025 Jun 23;13
Protocol for isolating extracellular vesicles from human or mouse airway macrophages for functional assays and in vivo or in vitro experimentation.
Sari E, Richter RP, Stacks DA, Lewis C, Smith JB, Xu N, Finley DC, Genschmer KR, Margaroli C
STAR protocols 2025 Jun 20;6(2):103867
STAR protocols 2025 Jun 20;6(2):103867
Loss of Bbs8 leads to cystic kidney disease in mice with reduced acetylation of ciliary alpha-tubulin through HDAC2.
Kieckhöfer E, Günzler J, Matthiessen PA, Ebert LK, Klausen C, Wachten D, Cetiner M, Liebau MC, Benzing T, May-Simera H, Schermer B
bioRxiv : the preprint server for biology 2025 Jun 17;
bioRxiv : the preprint server for biology 2025 Jun 17;
The crosstalk between lung adenocarcinoma cells and M2 macrophages promotes cancer cell development via the SFRS1/miR-708-5p/PD-L1 axis.
Xu L, Li K, Li J, Xu F, Liang S, Kong Y, Chen B
Life sciences 2025 Jun 15;371:123599
Life sciences 2025 Jun 15;371:123599
Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
Feng CZ, Zhong SQ, Ye SW, Zheng Z, Sun H, Zhou SH
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106161
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106161
Exploring Exosome Contributions to Gouty Arthritis: A Proteomics and Experimental Study.
Lu C, Yang X, Wang X, Wang Y, Zhang B, Lin Z
International journal of molecular sciences 2025 Jun 1;26(11)
International journal of molecular sciences 2025 Jun 1;26(11)
Ultrasound-Guided Functionalized Extracellular Vesicles for Visualized, Controlled, and Efficient Renal Delivery for Enhanced Kidney Repair.
Chen Y, Sheng C, Xiao T, Jiang B, Xu X, Cui S, Shen W, Zheng X, Guo X, Chen X, Zhang C, Cai G
Advanced healthcare materials 2025 Jul;14(17):e2404719
Advanced healthcare materials 2025 Jul;14(17):e2404719
Embryonic stem cell-derived small extracellular vesicles alleviate lead-induced cochlear spiral ganglion neurons injury by activating PI3 K/AKT signaling pathway.
Wang L, Bai Y, Sun Y, Li L, He Y, Li G, Liu D, Huang Z, Song J, Wu H, Li H, Wu X
Science progress 2025 Jul-Sep;108(3):368504251358007
Science progress 2025 Jul-Sep;108(3):368504251358007
Low-intensity pulsed ultrasound as a strategy to boost exosome secretion by adipose-derived stem cells and uptake for myocardial infarction therapy.
Jiang R, Wang H, Zhong F, Hu Y, Liu J, Chen Y, Su W, Cao S, Deng Q, Zhou Q
Biomedical materials (Bristol, England) 2025 Jul 9;20(4)
Biomedical materials (Bristol, England) 2025 Jul 9;20(4)
Zika virus disrupts steroidogenesis and impairs spermatogenesis by stalling the translation of CYP17A1 mRNA.
Yang W, Li H, Wang S, Huang R, Zhang Y, Guo M, Huang L, Li S, Yang R, Zhao D, Xiong Y, Liu Y, Huang M, Hui L, Xiao W, Wu Y
Nature communications 2025 Jul 22;16(1):6756
Nature communications 2025 Jul 22;16(1):6756
Injectable HAMA-CPC hydrogels loaded with high-yield 3D bioprinted adipose-derived stem cell small extracellular vesicles for increased bone repair.
Xu W, Gao W, Zhang Y, Hou G, Zhang W, Deng J, Wang K, Xu Y, Liu B, Xu T, Liu C, Liang T
Journal of nanobiotechnology 2025 Jul 21;23(1):531
Journal of nanobiotechnology 2025 Jul 21;23(1):531
Design, synthesis and biological evaluation of novel β-caryophyllene derivatives as potential anti-cancer agents through the ROS-mediated apoptosis pathway.
Wang Z, Chen Y, Huang A, Wen H, Wu Y, Xu X, Qiao Z, Chen L, Zhao Y, Liang X
RSC medicinal chemistry 2025 Jul 16;16(7):3174-3189
RSC medicinal chemistry 2025 Jul 16;16(7):3174-3189
Exosomal miRNA Profiling in Liquid Biopsy of Vitreous in Proliferative Diabetic Retinopathy.
Yan B, Qiu J, Yang Y, Luo J, Liu D, Zhang L, Meng Z, Li H, Guo X, Zeng J, Ding C, Xie M, Long K
Investigative ophthalmology & visual science 2025 Jul 1;66(9):24
Investigative ophthalmology & visual science 2025 Jul 1;66(9):24
Yellow Fever Virus Interactomes Reveal Common and Divergent Strategies of Replication and Evolution for Mosquito-borne Flaviviruses.
Kenaston MW, Cherkashchenko L, Skawinski CLS, Fishburn AT, Peddamallu V, Florio CJ, Robertson AE, Bhattacharya T, Young JM, Malik HS, Shah PS
bioRxiv : the preprint server for biology 2025 Jul 1;
bioRxiv : the preprint server for biology 2025 Jul 1;
The Lipid Droplet Protein DHRS3 Is a Regulator of Melanoma Cell State.
Johns E, Ma Y, Louphrasitthiphol P, Peralta C, Hunter MV, Raymond JH, Molina H, Goding CR, White RM
Pigment cell & melanoma research 2025 Jan;38(1):e13208
Pigment cell & melanoma research 2025 Jan;38(1):e13208
Enhancing epithelial regeneration with gelatin methacryloyl hydrogel loaded with extracellular vesicles derived from adipose mesenchymal stem cells for decellularized tracheal patching.
Lu Y, Shan Y, Zhu J, Shen Z, Chen W, Chen H, Shi H
International journal of biological macromolecules 2025 Jan;284(Pt 1):137927
International journal of biological macromolecules 2025 Jan;284(Pt 1):137927
BBSome-deficient cells activate intraciliary CDC42 to trigger actin-dependent ciliary ectocytosis.
Prasai A, Ivashchenko O, Maskova K, Bykova S, Schmidt Cernohorska M, Stepanek O, Huranova M
EMBO reports 2025 Jan;26(1):36-60
EMBO reports 2025 Jan;26(1):36-60
Calcium-mediated mitochondrial fission and mitophagy drive glycolysis to facilitate arterivirus proliferation.
Sun Z, Ma Z, Cao W, Jiang C, Guo L, Liu K, Gao Y, Bai J, Pi J, Jiang P, Liu X
PLoS pathogens 2025 Jan;21(1):e1012872
PLoS pathogens 2025 Jan;21(1):e1012872
Lipidomic and transcriptomic characteristics of boar seminal plasma extracellular vesicles associated with sperm motility.
Ding N, Zhang Y, Wang J, Liu J, Zhang J, Zhang C, Zhou L, Cao J, Jiang L
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jan;1870(1):159561
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jan;1870(1):159561
Improved Predictability of Diagnosis and Prognosis Using Serum- and Tissue-Derived Extracellular Vesicles From Bulk mRNA Sequencing in Pancreatic Ductal Adenocarcinoma.
Zhu Q, Chen Z, Tian M, Yan X, Gongye X, Liu Z, Zhao A, Yang Z, Yuan Y
Cancer medicine 2025 Jan;14(2):e70538
Cancer medicine 2025 Jan;14(2):e70538
A novel de novo GABRA2 gene missense variant causing developmental epileptic encephalopathy in a Chinese patient.
Yang L, Wan X, Hua R, Jiang J, Wang B, Tao R, Wu D
Annals of clinical and translational neurology 2025 Jan;12(1):137-148
Annals of clinical and translational neurology 2025 Jan;12(1):137-148
Efficient Isolation and Characterization Methods for Chicken Serum Extracellular Vesicles.
Mukohda H, Binici MM, Miyake K, Sano Y, Yamada T, Terada T, Sugiyama T
Animal science journal = Nihon chikusan Gakkaiho 2025 Jan-Dec;96(1):e70092
Animal science journal = Nihon chikusan Gakkaiho 2025 Jan-Dec;96(1):e70092
Inhibition of macrophage polarization and pyroptosis in collagen-induced arthritis through MSC-exo and ginsenoside Rh2.
Zhou Z, Wu S, Li Y, Shao P, Jiang J
Arthritis research & therapy 2025 Jan 9;27(1):6
Arthritis research & therapy 2025 Jan 9;27(1):6
Exosomal NEDD4L derived from HG+oxLDL-induced vascular endothelial cells accelerates macrophage M1 polarization and oxLDL uptake by ubiquitinating IκBα and PPARγ.
Chen G, Pei Y, Jiang P, Ye Q, Xie Z, Gyawali L
Cell biology and toxicology 2025 Jan 7;41(1):23
Cell biology and toxicology 2025 Jan 7;41(1):23
Ubiquitin ligase MARCH5 controls the formation of mitochondria-derived pre-peroxisomes.
Zheng J, Chen J, Cao Z, Wu K, Wang J, Guo Y, Zhuang M
Developmental cell 2025 Jan 6;60(1):30-39.e3
Developmental cell 2025 Jan 6;60(1):30-39.e3
Exosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity.
Can C, Yang X, Jia H, Wu H, Guo X, Wei Y, Jia Z, Liu W, Zhang A, He N, Zhang H, Ma D
Molecular cancer 2025 Jan 6;24(1):4
Molecular cancer 2025 Jan 6;24(1):4
One-dimensional nanosonosensitizer boosted multiple branches of immune responses against MHC-deficient immune-evasive urologic tumor.
Yang W, Di S, Yang Z, Cao J, Fu Q, Ren H, Cheng H, Xie Y, Jia W, Dai X, Yu M, Chen Y, Cui X
Science advances 2025 Jan 31;11(5):eado7373
Science advances 2025 Jan 31;11(5):eado7373
Dental pulp stem cell-derived intracellular vesicles prevent orthodontic relapse by inhibiting PI3K/Akt/NF-κB-mediated osteoclast activity.
Peng B, Li Z, Cheng Y, Jiang H, Ye Q, Han G
Stem cell research & therapy 2025 Jan 23;16(1):22
Stem cell research & therapy 2025 Jan 23;16(1):22
The Expression Pattern and Functional Analysis of Extracellular Vesicle Long Non-Coding RNAs from Uterine Fluid During Implantation in Pig.
Shang Y, Zhang Q, Ding Y, Wang Y, Gu S, Zang X, Xu Z, Huang S, Li Z, Wu Z, Gu T, Hong L, Cai G
Animals : an open access journal from MDPI 2025 Jan 16;15(2)
Animals : an open access journal from MDPI 2025 Jan 16;15(2)
Four-dimensional trapped ion mobility spectrometry proteomics reveals circulating extracellular vesicles encapsulated drivers of nasopharyngeal carcinoma distant dissemination.
Lu P, Yang L, Chen W, Li K, Chen X, Qu S
Talanta 2025 Jan 1;282:126907
Talanta 2025 Jan 1;282:126907
Choline kinase alpha regulates autophagy-associated exosome release to promote glioma cell progression.
Li J, Zhao Y, Wu X, Zou Y, Liu Y, Ma H
Biochemical and biophysical research communications 2025 Feb;746:151269
Biochemical and biophysical research communications 2025 Feb;746:151269
HIF-1α/BNIP3-Mediated Endoplasmic Reticulum Degradation via Autophagy Protects Against Ischemia Reperfusion-Induced Acute Kidney Injury.
Zhao H, Yang M, Han Y, Jiang N, Liu Y, Li C, Yang J, Luo S, Liu C, Sun L, Liu F, Liu Y
Antioxidants & redox signaling 2025 Feb;42(4-6):212-227
Antioxidants & redox signaling 2025 Feb;42(4-6):212-227
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy.
Jia X, Wang Y, Jiang M, Chen DD, Shang G, Liu B, Xue M, Lang Y, Zhou G, Dong Y, Zhang F, Peng X, Hu Y
The Journal of biological chemistry 2025 Feb;301(2):108126
The Journal of biological chemistry 2025 Feb;301(2):108126
PNPO-Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β-Catenin Pathway.
Deng Z, Sun S, Zhou N, Peng Y, Cheng L, Yu X, Yuan Y, Guo M, Xu M, Cheng Y, Zhou F, Li N, Yang Y, Gu C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2407681
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2407681
Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3.
Ye L, Shen S, Mao Q, Lu H, Liu H, Zhang P, Jiang Z, Ma W, Sun Y, Chu Y, Zhou Z, Liu R, Li J, Li ST, Gao P, Zhang H
Cell reports 2025 Feb 25;44(2):115250
Cell reports 2025 Feb 25;44(2):115250
Genomewide Screen Identifies Peroxisomal Role in APOL1 Podocytopathy.
Kim J, Karel IZ, Song H, Dewalt M, Orwick S, Buelow DR, Lee K, Brodsky SV, Blissett A, Cocucci E, Baker SD, Lin PH, Pabla NS, Madhavan SM
medRxiv : the preprint server for health sciences 2025 Feb 18;
medRxiv : the preprint server for health sciences 2025 Feb 18;
Metabolomic and Proteomic Profiling of Serum-Derived Extracellular Vesicles from Early-Stage Amyotrophic Lateral Sclerosis Patients.
Al Ojaimi Y, Vallet N, Dangoumau A, Lanznaster D, Bruno C, Lefevre A, Osman S, Dupuy C, Emond P, Vourc'h P, Corcia P, Krupova Z, Veyrat-Durebex C, Blasco H
Journal of molecular neuroscience : MN 2025 Feb 15;75(1):21
Journal of molecular neuroscience : MN 2025 Feb 15;75(1):21
Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury.
Li T, Xing HM, Qian HD, Gao Q, Xu SL, Ma H, Chi ZL
Neural regeneration research 2025 Feb 1;20(2):587-597
Neural regeneration research 2025 Feb 1;20(2):587-597
3D-cultured DFAT spheroid-derived exosomes promote aged wound healing via modulation of the NF-κB/Serpine1 pathway.
Ma X, Wei W, Zeng H, Dong M
Tissue & cell 2025 Dec;97:103049
Tissue & cell 2025 Dec;97:103049
Non-genetic inactivation of caspase-3 and P53 increases cancer cell fitness by PDIA4 redistribution.
Twito G, Abu Abayed FA, Gilad A, Biadsy S, Gavriel N, Sheikh Suliman S, Mizrahi Y, Megged H, Tenenboim M, Abu-Freha N, Igbaria A
Oncogene 2025 Dec;44(47):4565-4575
Oncogene 2025 Dec;44(47):4565-4575
Mesenchymal stem cell-derived small extracellular vesicles-loaded GelMA microspheres enhance diabetic wound healing by promoting M2 macrophage polarization through p38 MAPK inhibition.
Li W, Chen J, Yu L, Ding L, Zhang X, Yan L, Shi M
Materials today. Bio 2025 Dec;35:102423
Materials today. Bio 2025 Dec;35:102423
TLyp-1-modified exosome-mediated delivery of circRAPGEF5 ASO inhibits lung adenocarcinoma metastasis via regulating the miR-570-3p/SPP1 axis.
Hu T, Zhou C, Chen Y, Fu J, Dai Y, Ling L, Chen Y, Lu Y, He Y, Chen J, Wang Y
Materials today. Bio 2025 Dec;35:102416
Materials today. Bio 2025 Dec;35:102416
Engineered BMSC-derived exosomes deliver miR-17-5p inhibitor to restore sensory conduction via the IL-11/GP130/STAT3/GAP-43 axis in dorsal column lesion.
Wang Z, Zhang M, Wang F, Wang X, Song X, Wang X, Zhang L, Ren L, Jing X, Yang L, Wang T
International journal of biological macromolecules 2025 Dec;334(Pt 1):148958
International journal of biological macromolecules 2025 Dec;334(Pt 1):148958
Dietary monounsaturated fatty acid facilitates lipid droplet turnover through chaperone HSP90A-mediated lysosomal degradation of PLIN2 in hepatocellular carcinoma.
Luo X, Zhao J, Chen Q, Liu D, Lu Q, Tian C, Liu H, Yu X, He J, Ruan XZ, Yang P, Chen Y
Autophagy 2025 Dec;21(12):3287-3303
Autophagy 2025 Dec;21(12):3287-3303
GSTK1 and RETREG1/FAM134B-mediated reticulophagy attenuates tubular injury in diabetic nephropathy through endoplasmic reticulum stress and apoptosis.
Zhang S, Chen W, Wang W, Liu Y, Zhao C, Yang K, Dai W, Ou Y, Yin X, Long Y, Liu Y, Zhang L, Sun L, Liu F, Xiao L
Autophagy 2025 Dec;21(12):2826-2841
Autophagy 2025 Dec;21(12):2826-2841
CKAP4 in Extracellular Vesicle-Derived From Podocyte Serves as a Non-Invasive Diagnostic Biomarker for Diabetic Nephropathy and Promotes Vascular Calcification.
Zhang H, Lou K, Qian L, Zhang M, Li J, Lv L, Lu F, He G, Wu C, Wu J, Jia M, Bai Y, Qu S, Liu M, Chu L, Wang Y, Ding D, Zen K, Yuan Y, Liang H
Journal of extracellular vesicles 2025 Dec;14(12):e70208
Journal of extracellular vesicles 2025 Dec;14(12):e70208
ERβ/circAHNAK Axis Inhibits USP10-FMR1 Deubiquitination to Prevent m⁶A-Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma.
Xu C, Zhang S, Liu Y, Lv J, Cao Y, Chen Y, Sun H, Zhang B, Dai S, Li J, Li X, Shi B, Sun Q, Zhu M, Gu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e09654
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e09654
Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection.
Mehra C, Alvarado Valverde J, Matias AMN, Torelli F, Medeiros TC, Straub J, Asaki JD, Bradley PJ, Luck K, Lawo S, Treeck M, Pernas L
Nature microbiology 2025 Dec;10(12):3331-3345
Nature microbiology 2025 Dec;10(12):3331-3345
Macrophage-derived exosomal miR-466i-5p and miR-365-2-5p stimulated by BMP-2 promote osteogenesis.
Lu R, Dong H, Li W, Wang N, Yao Y, Chen S
Journal of orthopaedic surgery and research 2025 Dec 31;21(1):70
Journal of orthopaedic surgery and research 2025 Dec 31;21(1):70
Microglia-specific interleukin-4 delivery by engineered extracellular vesicles restores inner blood-retinal barrier in diabetic retinopathy via GAS6-MERTK pathway.
Fan Y, Ge P, Wang X, Xu J, Wang J, Li H, Gu Q, Xie H, Lin Y, Lu Y, Wang C, Xie P, Hu Z
Journal of nanobiotechnology 2025 Dec 29;24(1):101
Journal of nanobiotechnology 2025 Dec 29;24(1):101
Atosiban-conjugated 3WJ-pRNA nanoparticles delivering GAS1-enhanced extracellular vesicles: targeting the decidua to combat recurrent miscarriage.
Li YX, Wei SQ, Zheng PS
Journal of nanobiotechnology 2025 Dec 20;23(1):780
Journal of nanobiotechnology 2025 Dec 20;23(1):780
Liver-breast communication of adipocyte-oriented exosomes drives primary mammary cancer progression.
Li C, Lu Y, Li Y, Liu T, Deng H, Gao M, Zhou B, Liu J, Cai J, Huang D, Yang L, Jin J, Kuang D, Su S
Cell metabolism 2025 Dec 2;37(12):2402-2422.e18
Cell metabolism 2025 Dec 2;37(12):2402-2422.e18
SPLiCR-seq: A CRISPR-Based Screening Platform for RNA splicing Identifies Novel Regulators of IRE1α-XBP1 Signaling Under ER Stress.
Ying Q, Chen Y, Shen L, Xu Y, Tian R
Nature communications 2025 Dec 19;17(1):911
Nature communications 2025 Dec 19;17(1):911
MSC-sEV Promote Regeneration of Cochlear Spiral Ganglion Neurons and Myelin Sheaths in 3D Culture System.
You Y, Chen A, Qu J, Guo Y, Pan J, Yu T, Shu F, Tang J, Zhang H
Neuroscience bulletin 2025 Dec 19;
Neuroscience bulletin 2025 Dec 19;
Urine-Derived CD105-Positive Exosome Promotes Macrophage M1 Polarization Through the TGF-β1/Smad3 Signaling Axis To Exacerbate Lupus Nephritis.
Pang Y, Pan X, He L, Zuo Y, Wang X, You Y
Inflammation 2025 Dec 12;49(1):1
Inflammation 2025 Dec 12;49(1):1
β-caryolane derivatives as novel anti-colorectal cancer agents: synthesis and in vitro biological evaluation.
Xu X, Wang Z, Huang A, Qiao Z, Ge Y, Wen H, Cheng J, Zhao Y, Liang X
RSC advances 2025 Dec 12;15(58):49739-49750
RSC advances 2025 Dec 12;15(58):49739-49750
Exosomal miR-223-3p from mesenchymal stem cells targets FBXW7 to inhibit intervertebral disc degeneration: mechanism insights.
Chen R, Cao K, Gong Y, Zhu Y, Pan W, Zhou Q
Journal of orthopaedic surgery and research 2025 Dec 10;21(1)
Journal of orthopaedic surgery and research 2025 Dec 10;21(1)
Ubiquitination by HRD1 is essential for TLR3 trafficking and its innate immune signaling.
Zhao L, He Z, Sun Y, Sun M, Liu Z, Zhou Z, Qi L, Luo Y, Ji Y, Liang T
Nature communications 2025 Dec 10;17(1):525
Nature communications 2025 Dec 10;17(1):525
De-ubiquitinase USP35 promotes peritoneal dissemination of gastric cancer by regulating metabolic reprogramming.
Yan L, Chen M, Cai L, Liu A, Li F, Zhang Y, Peng X, Wang Y, Li R, Mei J, Zou D, Gao X, Wang Y, Wu L, Zhang Y
Cell death & disease 2025 Dec 10;16(1):889
Cell death & disease 2025 Dec 10;16(1):889
RalGAP complexes control secretion and primary cilia in pancreatic disease.
Apken LH, Barz H, Beel S, Michalke E, Rasche R, Verma A, Ricker A, Nüsse H, Klingauf J, Kerl K, Wardelmann E, Kümmel D, Steinestel K, Pethő Z, Meisterernst M, Oeckinghaus A
Life science alliance 2025 Aug;8(8)
Life science alliance 2025 Aug;8(8)
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice.
Li TT, Guo XF, Zhao YJ, Cheng YH, Xin DQ, Song Y, Liu DX, Wang Z
Acta pharmacologica Sinica 2025 Aug;46(8):2105-2119
Acta pharmacologica Sinica 2025 Aug;46(8):2105-2119
Deciphering the Proteomic Landscape of Circulating Extracellular Vesicles in Human Abdominal Aortic Aneurysm.
Yu C, Zhang G, Pei S, Zhang Y, Yuan P, Miao R, Kadier K, Zhang P, Gu T, Wu R, Zhang H, Zhang S, Yang B, Wu H, Xu Y, Hu K, Xu Q, Chen Y, Wang J, Cai Z, Tang J, Li T, Song Y
Journal of cellular and molecular medicine 2025 Aug;29(15):e70725
Journal of cellular and molecular medicine 2025 Aug;29(15):e70725
Vascular Smooth Muscle-Secreted Exosomal X26nt Impedes Atherosclerosis Progression via the c-FOS/XBP1/SOD1 Axis.
Zhang Z, Liu D, Zheng Y, Liu Y, Cheng X, Chang Y, Liang X, Hu X, Gao W
Immunity, inflammation and disease 2025 Aug;13(8):e70251
Immunity, inflammation and disease 2025 Aug;13(8):e70251
Exosomal miR-218 secreted from endothelial progenitor cells mitigates acute lung injury in sepsis mice by inhibiting HMGA1 in alveolar macrophages.
Liang G, Zeng M, Wang Q, Wang W, Liu J, Gao M, He Z
Stem cell research & therapy 2025 Aug 6;16(1):431
Stem cell research & therapy 2025 Aug 6;16(1):431
The foam cell-derived exosomes exacerbate ischemic white matter injury via transmitting metabolic defects to microglia.
Zhang H, Zhou LQ, Yang S, Dong MH, Chen L, Lu YL, Zhang LY, Zhang L, Chu YH, Xu LL, Pang XW, Zhu LF, Xu T, Yong TY, Wang W, Tian DS, Qin C
Cell metabolism 2025 Aug 5;37(8):1636-1654.e10
Cell metabolism 2025 Aug 5;37(8):1636-1654.e10
Proteomic Analysis of Differentially Expressed Plasma Exosome Proteins in Heat-Stressed Holstein cows.
Xia S, Jiang Y, Li W, An Z, Shen Y, Ding Q, Chen K
Animals : an open access journal from MDPI 2025 Aug 5;15(15)
Animals : an open access journal from MDPI 2025 Aug 5;15(15)
Exosomal Biglycan promotes gastric cancer progression via M2 polarization and CXCL10-mediated JAK/STAT1 activation.
Li W, Wei H, Liu J, Zhao Z, Wang F, Qiao L, Yin S, Zhang C, Huo M
Cancer letters 2025 Aug 28;626:217758
Cancer letters 2025 Aug 28;626:217758
Deletion of SH2D5 alleviates epileptic seizures and NMDAR expression via autophagic degradation of STAT1.
Guo H, Zhang H, Zhang C, Shen Y, Jiang L, Yang M, Zhang Y, Zhang N, Zhang R, Yu R, Yang Y, Tian X
JCI insight 2025 Aug 22;10(16)
JCI insight 2025 Aug 22;10(16)
Engineered MEVs for photoreceptor-targeted delivery of USP25 to alleviate diabetic retinopathy.
Sun Y, Chen S, Qi X, Sun Y, Jiang Z, Chang J, Ma Y, Huang J, You B, Sun F
Journal of nanobiotechnology 2025 Aug 20;23(1):575
Journal of nanobiotechnology 2025 Aug 20;23(1):575
hUC-MSCs and derived exosomes attenuate DEX-induced muscle atrophy through modulation of estrogen signaling pathway.
Li N, Liu X, Wang Q, Chen Y, Han C, Qu C, Guan X, Zou W, Wang X, Li A, Zhang Y, Zhu L, Du R, Liu J, Wang Y
Stem cell research & therapy 2025 Aug 2;16(1):419
Stem cell research & therapy 2025 Aug 2;16(1):419
A functionally tunable magnetic nanochains platform for N-glycoproteomic analysis of extracellular vesicles from ultratrace biofluids.
Li M, Song X, Tu H, Sun J, Deng Y, Wang B, Cai Y, Wang Y, Li B, Wang Y, Zhang X, Wei D, Yang X, Guo Y, Li X, Gu J, Ni J, Zhou Y, Gu Z, Xie Z, Li Y, Guo X
Nature communications 2025 Aug 16;16(1):7646
Nature communications 2025 Aug 16;16(1):7646
MRO/HNRNPU/CCL5 feedback loop amplifies M2 macrophage and breast cancer cell crosstalk to drive progression.
Zeng Z, Bao X, Lei S, Tang W, Tai H, Wang L, Li D, Liu S, Chen T
Journal of translational medicine 2025 Aug 15;23(1):920
Journal of translational medicine 2025 Aug 15;23(1):920
Host sphingolipids support Plasmodium berghei liver stage development.
Schroeder EA, Colón IC, Petruzziello PE, Derbyshire ER
mBio 2025 Aug 13;16(8):e0167525
mBio 2025 Aug 13;16(8):e0167525
Olfactory mucosa mesenchymal stem cell-derived exosomes protect against neuroinflammation after subarachnoid hemorrhage by activating mitophagy.
Wang J, Peng J, Gao L, He J, Lin L, Li JM, Xia Y
The Kaohsiung journal of medical sciences 2025 Apr;41(4):e12951
The Kaohsiung journal of medical sciences 2025 Apr;41(4):e12951
Sustained release of miR-21 carried by mesenchymal stem cell-derived exosomes from GelMA microspheres inhibits ovarian granulosa cell apoptosis in premature ovarian insufficiency.
Zhang X, Ma L, Liu X, Zhou X, Wang A, Lai Y, Zhang J, Li Y, Chen S
Materials today. Bio 2025 Apr;31:101469
Materials today. Bio 2025 Apr;31:101469
Upregulation of ISG15 induced by MAPT/tau accumulation represses autophagic flux by inhibiting HDAC6 activity: a vicious cycle in Alzheimer disease.
Liu Q, Wang X, Fang ZT, Zhao JN, Rui XX, Zhang BG, He Y, Liu RJ, Chen J, Chai GS, Liu GP
Autophagy 2025 Apr;21(4):807-826
Autophagy 2025 Apr;21(4):807-826
LIMA1 O-GlcNAcylation Promotes Hepatic Lipid Deposition through Inducing β-catenin-Regulated FASn Expression in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Yang F, Chen Y, Zheng G, Gu K, Fan L, Li T, Zhu L, Yan Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2415941
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2415941
Induced Pluripotent Stem Cell-Derived Exosomes Promote Peripheral Nerve Regeneration in a Rat Sciatic Nerve Crush Injury Model: A Safety and Efficacy Study.
Aldali F, Yang Y, Deng C, Li X, Cao X, Xu J, Li Y, Ding J, Chen H
Cells 2025 Apr 2;14(7)
Cells 2025 Apr 2;14(7)
Peptidomic profiling of mesenchymal stem cell-derived extracellular vesicles and anti-inflammatory activity of degraded peptides.
Chu T, Xiao Z, Xun C, Yang C, Lu M, Wang Y, Chen H, Chen P
International immunopharmacology 2025 Apr 16;152:114452
International immunopharmacology 2025 Apr 16;152:114452
Astrocyte-Derived Extracellular Vesicles Alleviate Optic Nerve Injury Through Remodeling of Retinal Microenvironmental Homeostasis.
Chen L, Yu Z, Zhu S, Song S, He G, Chi ZL, Wu W
Investigative ophthalmology & visual science 2025 Apr 1;66(4):16
Investigative ophthalmology & visual science 2025 Apr 1;66(4):16
Muscle-derived small extracellular vesicles induce liver fibrosis during overtraining.
Liu Y, Zhou R, Guo Y, Hu B, Xie L, An Y, Wen J, Liu Z, Zhou M, Kuang W, Xiao Y, Wang M, Xie G, Zhou H, Lu R, Peng H, Huang Y
Cell metabolism 2025 Apr 1;37(4):824-841.e8
Cell metabolism 2025 Apr 1;37(4):824-841.e8
Transcriptomic analysis of plasma-derived small extracellular vesicles reveals the pathological characteristics of normal tension glaucoma.
Xu SL, Li JH, Zhang WM, Fu MJ, Xing HM, Ma H, Gong XH, Wu RH, Liang YB, Cui RZ, Chi ZL
Extracellular vesicles and circulating nucleic acids 2024;5(3):438-454
Extracellular vesicles and circulating nucleic acids 2024;5(3):438-454
MAPK1 Mediates MAM Disruption and Mitochondrial Dysfunction in Diabetic Kidney Disease via the PACS-2-Dependent Mechanism.
Liu S, Han S, Wang C, Chen H, Xu Q, Feng S, Wang Y, Yao J, Zhou Q, Tang X, Lin L, Hu L, Davidson AJ, Yang B, Ye C, Yang F, Mao J, Tong C, Chen J, Jiang H
International journal of biological sciences 2024;20(2):569-584
International journal of biological sciences 2024;20(2):569-584
Metabolic Reprogramming of CD4(+) T Cells by Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuates Autoimmune Hepatitis Through Mitochondrial Protein Transfer.
Shen M, Zhou L, Fan X, Wu R, Liu S, Deng Q, Zheng Y, Liu J, Yang L
International journal of nanomedicine 2024;19:9799-9819
International journal of nanomedicine 2024;19:9799-9819
Non-Clinical Safety Evaluation of Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells in Cynomolgus Monkeys.
Hu XM, Wang CC, Xiao Y, Liu Y, Huang HR, Jiang P, Wang YK, Lin YJ, Li LC, Qi ZQ
International journal of nanomedicine 2024;19:4923-4939
International journal of nanomedicine 2024;19:4923-4939
Pretreatment of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes with Quercetin Enhances the Healing of Diabetic Skin Wounds by Modulating Host-Microbiota Interactions.
Wu S, Zhou Z, Li Y, Wu R, Jiang J
International journal of nanomedicine 2024;19:12557-12581
International journal of nanomedicine 2024;19:12557-12581
Key Magnetized Exosomes for Effective Targeted Delivery of Doxorubicin Against Breast Cancer Cell Types in Mice Model.
Xu W, Wang K, Wang K, Zhao Y, Yang Z, Li X
International journal of nanomedicine 2024;19:10711-10724
International journal of nanomedicine 2024;19:10711-10724
M1 Microglia-Derived Exosomes Promote A1 Astrocyte Activation and Aggravate Ischemic Injury via circSTRN3/miR-331-5p/MAVS/NF-κB Pathway.
Li Z, Xu P, Deng Y, Duan R, Peng Q, Wang S, Xu Z, Hong Y, Zhang Y
Journal of inflammation research 2024;17:9285-9305
Journal of inflammation research 2024;17:9285-9305
MiRNAs and Neutrophil-Related Membrane Proteins from Plasma-Derived Extracellular Vesicles for Early Prediction of Organ Dysfunction and Prognosis in Septic Patients.
Ye R, Wei Y, Li J, Xu M, Xie H, Huang J, Deng L, Li C
Journal of inflammation research 2024;17:10347-10369
Journal of inflammation research 2024;17:10347-10369
Immunomodulatory effect of PLGA-encapsulated mesenchymal stem cells-derived exosomes for the treatment of allergic rhinitis.
Shahzad KA, Wang Z, Li X, Li J, Xu M, Tan F
Frontiers in immunology 2024;15:1429442
Frontiers in immunology 2024;15:1429442
Influential factors on urine EV DNA methylation detection and its diagnostic potential in prostate cancer.
Ding T, Diao Y, Zeng X, Zhou L, Wu G, Liu J, Hao X
Frontiers in genetics 2024;15:1338468
Frontiers in genetics 2024;15:1338468
Photoreceptor-targeted extracellular vesicles-mediated delivery of Cul7 siRNA for retinal degeneration therapy.
Guo D, Sun Y, Wu J, Ding L, Jiang Y, Xue Y, Ma Y, Sun F
Theranostics 2024;14(13):4916-4932
Theranostics 2024;14(13):4916-4932
Engineered nanovesicles from activated neutrophils with enriched bactericidal proteins have molecular debridement ability and promote infectious wound healing.
Jin H, Wen X, Sun R, Yu Y, Guo Z, Yang Y, Li L, Sun B
Burns & trauma 2024;12:tkae018
Burns & trauma 2024;12:tkae018
Adipose mesenchymal stem cell-derived exosomes promote skin wound healing in diabetic mice by regulating epidermal autophagy.
Ren H, Su P, Zhao F, Zhang Q, Huang X, He C, Wu Q, Wang Z, Ma J, Wang Z
Burns & trauma 2024;12:tkae001
Burns & trauma 2024;12:tkae001
mRNA expression profiles in muscle-derived extracellular vesicles of Large White and wild boar piglets reveal their potential roles in immunity and muscle phenotype.
Yu N, Chang X, Hu J, Li J, Ma J, Huang L
Frontiers in veterinary science 2024;11:1452704
Frontiers in veterinary science 2024;11:1452704
CircPRRC2C Promotes the Oncogenic Phenotypes of Laryngeal Squamous Cell Carcinoma Cells via MiR-136-5p/HOXD11 Axis.
Peng X, Chen X, Peng S, Chen Y, Li Y, Tian Y
Molecular biotechnology 2024 Sep;66(9):2381-2395
Molecular biotechnology 2024 Sep;66(9):2381-2395
The expression profile of brain-derived exosomal miRNAs reveals the key molecules responsible for spontaneous motor function recovery in a rat model with permanent middle cerebral artery occlusion.
Liu L, Chen S, Liang S, Liang Z
Mammalian genome : official journal of the International Mammalian Genome Society 2024 Sep;35(3):362-376
Mammalian genome : official journal of the International Mammalian Genome Society 2024 Sep;35(3):362-376
Human Umbilical Cord Mesenchymal Stem Cells-Derived Extracellular Vesicles for Rat Jawbone Regeneration in Periapical Periodontitis.
Gao J, Zhu D, Fan Y, Liu H, Shen Z
ACS biomaterials science & engineering 2024 Sep 9;10(9):5784-5795
ACS biomaterials science & engineering 2024 Sep 9;10(9):5784-5795
Discovery of novel quinoline scaffold selective estrogen receptor degraders (SERDs) for treatment of ER positive breast cancer with enhanced antiproliferative bioactivity through immunogenic cell death (ICD) effects.
Lu Y, Liang Z, Liu L, Zhou Y, Liu C, Zhao Z, Zheng T, Du Q, Liu W
European journal of medicinal chemistry 2024 Sep 5;275:116534
European journal of medicinal chemistry 2024 Sep 5;275:116534
Rate of hydrolysis of the phosphate esters of B vitamins is reduced by zinc deficiency: In vitro and in vivo.
Yuasa H, Miyazaki K, Kido T, Nishino K, Shiotsu M, Fukuwatari T, Suka M, Nagao M, Kambe T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 30;38(18):e70025
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 30;38(18):e70025
The Delayed Turnover of Proteasome Processing of Myocilin upon Dexamethasone Stimulation Introduces the Profiling of Trabecular Meshwork Cells' Ubiquitylome.
Tundo GR, Cavaterra D, Pandino I, Zingale GA, Giammaria S, Boccaccini A, Michelessi M, Roberti G, Tanga L, Carnevale C, Figus M, Grasso G, Coletta M, Bocedi A, Oddone F, Sbardella D
International journal of molecular sciences 2024 Sep 17;25(18)
International journal of molecular sciences 2024 Sep 17;25(18)
Circulating exosomal circRNA-miRNA-mRNA network in a familial partial lipodystrophy type 3 family with a novel PPARG frameshift mutation c.418dup.
Zhou L, Li S, Ren J, Wang D, Yu R, Zhao Y, Zhang Q, Xiao X
American journal of physiology. Endocrinology and metabolism 2024 Sep 1;327(3):E357-E370
American journal of physiology. Endocrinology and metabolism 2024 Sep 1;327(3):E357-E370
Stereotactically intracerebral transplantation of neural stem cells for ischemic stroke attenuated inflammatory responses and promoted neurogenesis: an experimental study with monkeys.
Liu YF, Liu HT, Chang C, Yang CX, Liu XN, Wang X, Ge W, Wang RZ, Bao XJ
International journal of surgery (London, England) 2024 Sep 1;110(9):5417-5433
International journal of surgery (London, England) 2024 Sep 1;110(9):5417-5433
EPDR1 promotes PD-L1 expression and tumor immune evasion by inhibiting TRIM21-dependent ubiquitylation of IkappaB kinase-β.
Qian X, Cai J, Zhang Y, Shen S, Wang M, Liu S, Meng X, Zhang J, Ye Z, Qiu S, Zhong X, Gao P
The EMBO journal 2024 Oct;43(19):4248-4273
The EMBO journal 2024 Oct;43(19):4248-4273
Functional exosomes modified with chitosan effectively alleviate anthracycline-induced cardiotoxicity.
Wen Z, Qin S, Huang H, Xia X, Zhang W, Wu W
International journal of biological macromolecules 2024 Oct;277(Pt 3):134495
International journal of biological macromolecules 2024 Oct;277(Pt 3):134495
Research on the role of exosomes secreted by immortalized adipose-derived mesenchymal stem cells differentiated into pericytes in the repair of high glucose-induced retinal vascular endothelial cell damage.
Wu S, Zhang Y, Hou Y, Zhu J, Yang H, Cui Y
Experimental eye research 2024 Oct;247:110046
Experimental eye research 2024 Oct;247:110046
Exosomes Derived from Rejuvenated Stem Cells Inactivate NLRP3 Inflammasome and Pyroptosis of Nucleus Pulposus Cells via the Transfer of Antioxidants.
Peng S, Liu X, Chang L, Liu B, Zhang M, Mao Y, Shen X
Tissue engineering and regenerative medicine 2024 Oct;21(7):1061-1077
Tissue engineering and regenerative medicine 2024 Oct;21(7):1061-1077
Pharmacological chaperones restore proteostasis of epilepsy-associated GABA(A) receptor variants.
Wang YJ, Seibert H, Ahn LY, Schaffer AE, Mu TW
Pharmacological research 2024 Oct;208:107356
Pharmacological research 2024 Oct;208:107356
Intratympanic injection of MSC-derived small extracellular vesicles protects spiral ganglion neurons from degeneration.
Chen A, Qu J, You Y, Pan J, Scheper V, Lin Y, Tian X, Shu F, Luo Y, Tang J, Zhang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117392
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117392
Milk-Derived Extracellular Vesicles Carrying ssc-let-7c Alleviate Early Intestinal Inflammation and Regulate Macrophage Polarization via Targeting the PTEN-Mediated PI3K/Akt Pathway.
Lu D, Zhang X, Ye H, Wang J, Han D
Journal of agricultural and food chemistry 2024 Oct 9;72(40):22092-22104
Journal of agricultural and food chemistry 2024 Oct 9;72(40):22092-22104
Bioenergetic-active exosomes for cartilage regeneration and homeostasis maintenance.
Liu X, Jiang S, Jiang T, Lan Z, Zhang X, Zhong Z, Wu X, Xu C, Du Y, Zhang S
Science advances 2024 Oct 18;10(42):eadp7872
Science advances 2024 Oct 18;10(42):eadp7872
Priming Mesenchymal Stem Cells with Lipopolysaccharide Boosts the Immunomodulatory and Regenerative Activity of Secreted Extracellular Vesicles.
Areny-Balagueró A, Camprubí-Rimblas M, Campaña-Duel E, Solé-Porta A, Ceccato A, Roig A, Laffey JG, Closa D, Artigas A
Pharmaceutics 2024 Oct 10;16(10)
Pharmaceutics 2024 Oct 10;16(10)
Quercetin inhibits endothelial & hepatocellular carcinoma cell crosstalk via reducing extracellular vesicle-mediated VEGFR2 mRNA transfer.
Xiong W, Zheng B, Liu D, Pu M, Zhou S, Deng Y
Molecular carcinogenesis 2024 Nov;63(11):2254-2268
Molecular carcinogenesis 2024 Nov;63(11):2254-2268
Comparative investigation of exosome extraction from rat bone marrow mesenchymal stem cells using three different methodologies.
Wang N, Yin M, Yu J, Zhang J, Pan X
Electrophoresis 2024 Nov;45(21-22):2045-2053
Electrophoresis 2024 Nov;45(21-22):2045-2053
Ammonia-induced lysosomal and mitochondrial damage causes cell death of effector CD8(+) T cells.
Zhang H, Liu J, Yuan W, Zhang Q, Luo X, Li Y, Peng Y, Feng J, Liu X, Chen J, Zhou Y, Lv J, Zhou N, Ma J, Tang K, Huang B
Nature cell biology 2024 Nov;26(11):1892-1902
Nature cell biology 2024 Nov;26(11):1892-1902
Kinesin-1 mediates proper ER folding of the Ca(V)1.2 channel and maintains mouse glucose homeostasis.
Tanaka Y, Farkhondeh A, Yang W, Ueno H, Noda M, Hirokawa N
EMBO reports 2024 Nov;25(11):4777-4802
EMBO reports 2024 Nov;25(11):4777-4802
Jiedu recipe, a compound Chinese herbal medicine, suppresses hepatocellular carcinoma metastasis by inhibiting the release of tumor-derived exosomes in a hypoxic microenvironment.
Jia WT, Xiang S, Zhang JB, Yuan JY, Wang YQ, Liang SF, Lin WF, Zhai XF, Shang Y, Ling CQ, Cheng BB
Journal of integrative medicine 2024 Nov;22(6):696-708
Journal of integrative medicine 2024 Nov;22(6):696-708
PlexinA1 (PLXNA1) as a novel scaffold protein for the engineering of extracellular vesicles.
Zhao H, Li Z, Liu D, Zhang J, You Z, Shao Y, Li H, Yang J, Liu X, Wang M, Wu C, Chen J, Wang J, Kong G, Zhao L
Journal of extracellular vesicles 2024 Nov;13(11):e70012
Journal of extracellular vesicles 2024 Nov;13(11):e70012
Zosuquidar Promotes Antitumor Immunity by Inducing Autophagic Degradation of PD-L1.
Ding L, Guo H, Zhang J, Zheng M, Zhang W, Wang L, Du Q, Zhou C, Xu Y, Wu H, He Q, Yang B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2400340
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2400340
EP152R-mediated endoplasmic reticulum stress contributes to African swine fever virus infection via the PERK-eIF2α pathway.
Liang R, Fu Y, Li G, Shen Z, Guo F, Shi J, Guo Y, Zhang D, Wang Z, Chen C, Shi Y, Peng G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 30;38(22):e70187
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 30;38(22):e70187
Time-series metabolomic analysis revealed altered metabolism of cynomolgus monkeys after injecting exosomes.
Hu X, Wang C, Xiao Y, Jiang P, Huang D, Li LC, Qi Z
Journal of nanobiotechnology 2024 Nov 26;22(1):732
Journal of nanobiotechnology 2024 Nov 26;22(1):732
Mesenchymal stromal cells deliver H(2)S-enhanced Nrf2 via extracellular vesicles to mediate mitochondrial homeostasis for repairing hypoxia-ischemia brain damage.
Gai C, Li T, Zhao Y, Cheng Y, Song Y, Luo Q, Liu D, Wang Z
Free radical biology & medicine 2024 Nov 20;225:528-545
Free radical biology & medicine 2024 Nov 20;225:528-545
Pancreatic cancer-derived exosomal miR-510 promotes macrophage M2 polarization and facilitates cancer cell aggressive phenotypes.
Wang T, Ye L, Zhou Y, Zhang X, Li R, Zhou Y, Weng J, Mo Q, Yu Y
Human cell 2024 Nov 12;38(1):17
Human cell 2024 Nov 12;38(1):17
Treatment of Parkinson's disease model with human umbilical cord mesenchymal stem cell-derived exosomes loaded with BDNF.
Wang CC, Hu XM, Long YF, Huang HR, He Y, Xu ZR, Qi ZQ
Life sciences 2024 Nov 1;356:123014
Life sciences 2024 Nov 1;356:123014
Plasma exosomes impair microglial degradation of α-synuclein through V-ATPase subunit V1G1.
Li Y, Wang Y, Kou L, Yin S, Chi X, Sun Y, Wu J, Jin Z, Zhou Q, Zou W, Wang T, Xia Y
CNS neuroscience & therapeutics 2024 May;30(5):e14738
CNS neuroscience & therapeutics 2024 May;30(5):e14738
Effect of human periodontal ligament stem cell-derived exosomes on cementoblast activity.
Li S, Guan X, Yu W, Zhao Z, Sun Y, Bai Y
Oral diseases 2024 May;30(4):2511-2522
Oral diseases 2024 May;30(4):2511-2522
Analysis of the effects of M2 macrophage-derived PDE4C on the prognosis, metastasis and immunotherapy benefit of osteosarcoma.
Pan F, Pan R, Hu R, Zhang H, Lei S, Zhang L, Zhou C, Zeng Z, Tian X, Xie Q
Journal of cellular and molecular medicine 2024 May;28(10):e18395
Journal of cellular and molecular medicine 2024 May;28(10):e18395
Macrophage-derived ectosomal miR-350-3p promotes osteoarthritis progression through downregulating chondrocyte H3K36 methyltransferase NSD1.
Lin R, Yin J, Huang J, Zou L, Liu L, Tang W, Zhang H, Yang L, Zhang Y, Li G, Wang G, Cai D, Zhang H, Liu Y, Shao Y
Cell death discovery 2024 May 8;10(1):223
Cell death discovery 2024 May 8;10(1):223
Lipotoxic hepatocyte derived LIMA1 enriched small extracellular vesicles promote hepatic stellate cells activation via inhibiting mitophagy.
Li S, Yang F, Cheng F, Zhu L, Yan Y
Cellular & molecular biology letters 2024 May 31;29(1):82
Cellular & molecular biology letters 2024 May 31;29(1):82
mir-605-3p prevents liver premetastatic niche formation by inhibiting angiogenesis via decreasing exosomal nos3 release in gastric cancer.
Hu Y, Zang W, Feng Y, Mao Q, Chen J, Zhu Y, Xue W
Cancer cell international 2024 May 27;24(1):184
Cancer cell international 2024 May 27;24(1):184
ANXA3-Rich Exosomes Derived from Tumor-Associated Macrophages Regulate Ferroptosis and Lymphatic Metastasis of Laryngeal Squamous Cell Carcinoma.
Xu L, Li W, Liu D, Cao J, Ge J, Liu X, Wang Y, Teng Y, Liu P, Guo X, He C, Liu M, Tian L
Cancer immunology research 2024 May 2;12(5):614-630
Cancer immunology research 2024 May 2;12(5):614-630
Exosome-mediated Delivery of miR-519e-5p Promotes Malignant Tumor Phenotype and CD8+ T-Cell Exhaustion in Metastatic PTC.
Li G, Chen W, Jiang K, Huang J, Zhong J, Liu X, Wei T, Gong R, Li Z, Zhu J, Shi H, Lei J
The Journal of clinical endocrinology and metabolism 2024 May 17;109(6):1601-1617
The Journal of clinical endocrinology and metabolism 2024 May 17;109(6):1601-1617
An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins.
Ji J, Cui MK, Zou R, Wu MZ, Ge MX, Li J, Zhang ZR
Molecular cell 2024 May 16;84(10):1917-1931.e15
Molecular cell 2024 May 16;84(10):1917-1931.e15
Detection of fucosylated extracellular vesicles miR-4732-5p related to diagnosis of early lung adenocarcinoma by the electrochemical biosensor.
Zhu S, Chen J, Yu L, Li J, You S, Zheng Y, Zhuang W, Qiu B, Huang Y
Scientific reports 2024 May 16;14(1):11217
Scientific reports 2024 May 16;14(1):11217
Low‑intensity pulsed ultrasound accelerates diabetic wound healing by ADSC‑derived exosomes via promoting the uptake of exosomes and enhancing angiogenesis.
Zhong F, Cao S, Yang L, Liu J, Gui B, Wang H, Jiang N, Zhou Q, Deng Q
International journal of molecular medicine 2024 Mar;53(3)
International journal of molecular medicine 2024 Mar;53(3)
Transcriptome sequencing of circular RNA reveals the involvement of hsa-SCMH1_0001 in the pathogenesis of Parkinson's disease.
Wang Q, Wang H, Zhao X, Han C, Liu C, Li Z, Du T, Sui Y, Zhang X, Zhang J, Xiao Y, Cai G, Meng F
CNS neuroscience & therapeutics 2024 Mar;30(3):e14435
CNS neuroscience & therapeutics 2024 Mar;30(3):e14435
Exosome co-delivery of a STING agonist augments immunogenicity elicited by CVB3 VP1 vaccine via promoting antigen cross-presentation of CD8 (+) DCs.
Zhang C, Cao Q, Li Y, Lu J, Xiong S, Yue Y
International journal of biological macromolecules 2024 Mar;261(Pt 1):129518
International journal of biological macromolecules 2024 Mar;261(Pt 1):129518
Combinatorial selective ER-phagy remodels the ER during neurogenesis.
Hoyer MJ, Capitanio C, Smith IR, Paoli JC, Bieber A, Jiang Y, Paulo JA, Gonzalez-Lozano MA, Baumeister W, Wilfling F, Schulman BA, Harper JW
Nature cell biology 2024 Mar;26(3):378-392
Nature cell biology 2024 Mar;26(3):378-392
Chemical Proteomics Reveals N(ε)-Fatty-Acylation of Septins by Rho Inactivation Domain (RID) of the Vibrio MARTX Toxin to Alter Septin Localization and Organization.
Xu Y, Ding K, Peng T
Molecular & cellular proteomics : MCP 2024 Mar;23(3):100730
Molecular & cellular proteomics : MCP 2024 Mar;23(3):100730
Intracerebral fate of organic and inorganic nanoparticles is dependent on microglial extracellular vesicle function.
Gao J, Song Q, Gu X, Jiang G, Huang J, Tang Y, Yu R, Wang A, Huang Y, Zheng G, Chen H, Gao X
Nature nanotechnology 2024 Mar;19(3):376-386
Nature nanotechnology 2024 Mar;19(3):376-386
SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins.
Zheng N, Liu S, Chen J, Xu Y, Cao W, Lin J, Lu G, Zhang G
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159
NDUFS4 regulates cristae remodeling in diabetic kidney disease.
Mise K, Long J, Galvan DL, Ye Z, Fan G, Sharma R, Serysheva II, Moore TI, Jeter CR, Anna Zal M, Araki M, Wada J, Schumacker PT, Chang BH, Danesh FR
Nature communications 2024 Mar 4;15(1):1965
Nature communications 2024 Mar 4;15(1):1965
The lipid droplet protein DHRS3 is a regulator of melanoma cell state.
Johns E, Ma Y, Louphrasitthipol P, Peralta C, Hunter MV, Raymond JH, Molina H, Goding CR, White RM
bioRxiv : the preprint server for biology 2024 Mar 28;
bioRxiv : the preprint server for biology 2024 Mar 28;
Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis.
Chen G, Li X, Zhou X, Li Y, Yu H, Peng X, Bai X, Zhang C, Feng Z, Mei Y, Li L, Liu Y, Gou X, Jiang Y
Scientific reports 2024 Mar 20;14(1):6720
Scientific reports 2024 Mar 20;14(1):6720
Metabolic profiling in tissues and urine of patients with prostatic lesions and the diagnostic value of urine extracellular vesicles metabolites in prostate cancer.
Ding T, He W, Yan H, Wei Z, Zeng X, Hao X
Clinica chimica acta; international journal of clinical chemistry 2024 Mar 15;556:117845
Clinica chimica acta; international journal of clinical chemistry 2024 Mar 15;556:117845
Exosomes derived from umbilical cord mesenchymal stem cells ameliorate male infertility caused by busulfan in vivo and in vitro.
Yue D, Wang F, Han Y, Xiong C, Yang R
Ecotoxicology and environmental safety 2024 Mar 1;272:116063
Ecotoxicology and environmental safety 2024 Mar 1;272:116063
Peritumoral SPARC expression induced by exosomes from nasopharyngeal carcinoma infected Epstein-Barr virus: A poor prognostic marker.
Dochi H, Kondo S, Komura S, Moriyama-Kita M, Komori T, Nanbo A, Sakaguchi M, Fukuyo M, Hamabe-Horiike T, Tanaka M, Mizokami H, Kano M, Kitagawa Y, Kobayashi E, Hirai N, Ueno T, Nakanishi Y, Endo K, Sugimoto H, Hanayama R, Kaneda A, Yoshizaki T
International journal of cancer 2024 Mar 1;154(5):895-911
International journal of cancer 2024 Mar 1;154(5):895-911
A virally encoded high-resolution screen of cytomegalovirus dependencies.
Finkel Y, Nachshon A, Aharon E, Arazi T, Simonovsky E, Dobešová M, Saud Z, Gluck A, Fisher T, Stanton RJ, Schwartz M, Stern-Ginossar N
Nature 2024 Jun;630(8017):712-719
Nature 2024 Jun;630(8017):712-719
Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting.
Ma W, Wu D, Long C, Liu J, Xu L, Zhou L, Dou Q, Ge Y, Zhou C, Jia R
Journal of controlled release : official journal of the Controlled Release Society 2024 Jun;370:66-81
Journal of controlled release : official journal of the Controlled Release Society 2024 Jun;370:66-81
ZNT5-6 and ZNT7 play an integral role in protein N-glycosylation by supplying Zn(2+) to Golgi α-mannosidase II.
Yuasa H, Morino N, Wagatsuma T, Munekane M, Ueda S, Matsunaga M, Uchida Y, Katayama T, Katoh T, Kambe T
The Journal of biological chemistry 2024 Jun;300(6):107378
The Journal of biological chemistry 2024 Jun;300(6):107378
Exosomal lncRNA-MIAT promotes neovascularization via the miR-133a-3p/MMP-X1 axis in diabetic retinopathy.
Li X, Cao Q, Xu C, Wang J, Pan T, Liu Q, Xie P, Hu Z
Experimental eye research 2024 Jun;243:109912
Experimental eye research 2024 Jun;243:109912
Plasma exosomes from patients with active thyroid-associated orbitopathy induce inflammation and fibrosis in orbital fibroblasts.
Wei L, Huang Q, Tu Y, Song S, Zhang X, Yu B, Liu Y, Li Z, Huang Q, Chen L, Liu B, Xu S, Li T, Liu X, Hu X, Liu W, Chi ZL, Wu W
Journal of translational medicine 2024 Jun 7;22(1):546
Journal of translational medicine 2024 Jun 7;22(1):546
Extracellular vesicles activated cancer-associated fibroblasts promote lung cancer metastasis through mitophagy and mtDNA transfer.
Zhou Z, Qu C, Zhou P, Zhou Q, Li D, Wu X, Yang L
Journal of experimental & clinical cancer research : CR 2024 Jun 3;43(1):158
Journal of experimental & clinical cancer research : CR 2024 Jun 3;43(1):158
Macrophage Phenotype Induced by Circulating Small Extracellular Vesicles from Women with Endometriosis.
Martínez-Zamora MA, Armengol-Badia O, Quintas-Marquès L, Carmona F, Closa D
Biomolecules 2024 Jun 21;14(7)
Biomolecules 2024 Jun 21;14(7)
Engineered extracellular vesicle-based gene therapy for the treatment of discogenic back pain.
Tang SN, Salazar-Puerta AI, Heimann MK, Kuchynsky K, Rincon-Benavides MA, Kordowski M, Gunsch G, Bodine L, Diop K, Gantt C, Khan S, Bratasz A, Kokiko-Cochran O, Fitzgerald J, Laudier DM, Hoyland JA, Walter BA, Higuita-Castro N, Purmessur D
Biomaterials 2024 Jul;308:122562
Biomaterials 2024 Jul;308:122562
Reducing Oxidative Stress-Mediated Alcoholic Liver Injury by Multiplexed RNAi of Cyp2e1, Cyp4a10, and Cyp4a14.
Zhang Q, Wu S, Chen Q, Zhang Y, Zhang C, Yin R, Ouyang Z, Wei Y
Biomedicines 2024 Jul 6;12(7)
Biomedicines 2024 Jul 6;12(7)
N6-Methyladenosine enhances the translation of ENO1 to promote the progression of bladder cancer by inhibiting PCNA ubiquitination.
Shen C, Liu J, Xie F, Yu Y, Ma X, Hu D, Liu C, Wang Y
Cancer letters 2024 Jul 28;595:217002
Cancer letters 2024 Jul 28;595:217002
M1 macrophage-derived exosomes inhibit cardiomyocyte proliferation through delivering miR-155.
He X, Liu S, Zhang Z, Liu Q, Dong J, Lin Z, Chen J, Li L, Liu W, Liu S, Liu S
BMC cardiovascular disorders 2024 Jul 16;24(1):365
BMC cardiovascular disorders 2024 Jul 16;24(1):365
Yoda1 pretreated BMSC derived exosomes accelerate osteogenesis by activating phospho-ErK signaling via Yoda1-mediated signal transmission.
He X, Liu Y, Dai Z, Chen Y, Liu W, Dai H, Hu Y
Journal of nanobiotechnology 2024 Jul 10;22(1):407
Journal of nanobiotechnology 2024 Jul 10;22(1):407
Astragaloside IV promotes exosome secretion of endothelial progenitor cells to regulate PI3KR2/SPRED1 signaling and inhibit pyroptosis of diabetic endothelial cells.
Xiong W, Zhang X, Zhou J, Chen J, Liu Y, Yan Y, Tan M, Huang H, Si Y, Wei Y
Cytotherapy 2024 Jan;26(1):36-50
Cytotherapy 2024 Jan;26(1):36-50
Osteoblast-derived exosomes promote osteogenic differentiation of osteosarcoma cells via URG4/Wnt signaling pathway.
Leng Y, Li J, Long Z, Li C, Zhang L, Huang Z, Xi J, Liu Y
Bone 2024 Jan;178:116933
Bone 2024 Jan;178:116933
Human umbilical cord mesenchymal stem cells improve disease characterization of Sjogren's syndrome in NOD mice through regulation of gut microbiota and Treg/Th17 cellular immunity.
Zou Y, Xiao W, Liu D, Li X, Li L, Peng L, Xiong Y, Gan H, Ren X
Immunity, inflammation and disease 2024 Jan;12(1):e1139
Immunity, inflammation and disease 2024 Jan;12(1):e1139
Nuclear membrane protein SUN2 promotes replication of flaviviruses through modulating cytoskeleton reorganization mediated by NS1.
Huang Y, Peng Q, Tian X, Chen C, Zhu X, Huang C, Huo Z, Liu Y, Yang C, Liu C, Zhang P
Nature communications 2024 Jan 5;15(1):296
Nature communications 2024 Jan 5;15(1):296
Lactate-lactylation-HSPA6 axis promotes PRRSV replication by impairing IFN-β production.
Pang Y, Zhou Y, Wang Y, Fang L, Xiao S
Journal of virology 2024 Jan 23;98(1):e0167023
Journal of virology 2024 Jan 23;98(1):e0167023
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
Wang W, Ren X, Chen X, Hong Q, Cai G
JCI insight 2024 Jan 23;9(2)
JCI insight 2024 Jan 23;9(2)
Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral disc.
Jia C, Xiang Z, Zhang P, Liu L, Zhu X, Yu R, Liu Z, Wang S, Liu K, Wang Z, Vasilev K, Zhou S, Geng Z, Liu X, Zhao Y, Gao Y, Cheng L, Li Y
Cellular and molecular life sciences : CMLS 2024 Jan 22;81(1):49
Cellular and molecular life sciences : CMLS 2024 Jan 22;81(1):49
Delphinidins from Maqui Berry (Aristotelia chilensis) ameliorate the subcellular organelle damage induced by blue light exposure in murine photoreceptor-derived cells.
Yamazaki K, Ishida K, Otsu W, Muramatsu A, Nakamura S, Yamada W, Tsusaki H, Shimoda H, Hara H, Shimazawa M
BMC complementary medicine and therapies 2024 Jan 2;24(1):3
BMC complementary medicine and therapies 2024 Jan 2;24(1):3
PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4.
Tao H, Song SJ, Fan ZW, Li WT, Jin X, Jiang W, Bai J, Shi ZZ
Antioxidants (Basel, Switzerland) 2024 Jan 17;13(1)
Antioxidants (Basel, Switzerland) 2024 Jan 17;13(1)
Single-molecule localization microscopy reveals STING clustering at the trans-Golgi network through palmitoylation-dependent accumulation of cholesterol.
Kemmoku H, Takahashi K, Mukai K, Mori T, Hirosawa KM, Kiku F, Uchida Y, Kuchitsu Y, Nishioka Y, Sawa M, Kishimoto T, Tanaka K, Yokota Y, Arai H, Suzuki KGN, Taguchi T
Nature communications 2024 Jan 11;15(1):220
Nature communications 2024 Jan 11;15(1):220
Tumor-associated macrophage-derived exosomal miR-513b-5p is a target of jianpi yangzheng decoction for inhibiting gastric cancer.
Zhang R, Chen X, Miao C, Chen Y, Li Y, Shen J, Yuan M, Chen M, Cheng J, Liu S, Sun Q, Wu J
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117013
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117013
The effects of boar seminal plasma extracellular vesicles on sperm fertility.
Xu Z, Xie Y, Wu C, Gu T, Zhang X, Yang J, Yang H, Zheng E, Huang S, Xu Z, Li Z, Cai G, Liu D, Hong L, Wu Z
Theriogenology 2024 Jan 1;213:79-89
Theriogenology 2024 Jan 1;213:79-89
Adapting the endoplasmic reticulum proteostasis rescues epilepsy-associated NMDA receptor variants.
Zhang PP, Benske TM, Ahn LY, Schaffer AE, Paton JC, Paton AW, Mu TW, Wang YJ
Acta pharmacologica Sinica 2024 Feb;45(2):282-297
Acta pharmacologica Sinica 2024 Feb;45(2):282-297
Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis.
Zhang W, Zhang Z, Xiang Y, Gu DD, Chen J, Chen Y, Zhai S, Liu Y, Jiang T, Liu C, He B, Yan M, Wang Z, Xu J, Cao YL, Deng B, Zeng D, Lei J, Zhuo J, Lei X, Long Z, Jin B, Chen T, Li D, Shen Y, Hu J, Gao S, Liu Q
Nature structural & molecular biology 2024 Feb;31(2):219-231
Nature structural & molecular biology 2024 Feb;31(2):219-231
UBXN1 maintains ER proteostasis and represses UPR activation by modulating translation.
Ahlstedt BA, Ganji R, Mukkavalli S, Paulo JA, Gygi SP, Raman M
EMBO reports 2024 Feb;25(2):672-703
EMBO reports 2024 Feb;25(2):672-703
MiR-141-3p-Functionalized Exosomes Loaded in Dissolvable Microneedle Arrays for Hypertrophic Scar Treatment.
Meng S, Wei Q, Chen S, Liu X, Cui S, Huang Q, Chu Z, Ma K, Zhang W, Hu W, Li S, Wang Z, Tian L, Zhao Z, Li H, Fu X, Zhang C
Small (Weinheim an der Bergstrasse, Germany) 2024 Feb;20(8):e2305374
Small (Weinheim an der Bergstrasse, Germany) 2024 Feb;20(8):e2305374
Interorgan communication in neurogenic heterotopic ossification: the role of brain-derived extracellular vesicles.
Lu W, Yan J, Wang C, Qin W, Han X, Qin Z, Wei Y, Xu H, Gao J, Gao C, Ye T, Tay FR, Niu L, Jiao K
Bone research 2024 Feb 22;12(1):11
Bone research 2024 Feb 22;12(1):11
SYNJ2BP ameliorates intervertebral disc degeneration by facilitating mitochondria-associated endoplasmic reticulum membrane formation and mitochondrial Zn(2+) homeostasis.
Song Y, Geng W, Zhu D, Liang H, Du Z, Tong B, Wang K, Li S, Gao Y, Feng X, Liao Z, Mei R, Yang C
Free radical biology & medicine 2024 Feb 20;212:220-233
Free radical biology & medicine 2024 Feb 20;212:220-233
M2 macrophage-derived exosomal miR-26b-5p regulates macrophage polarization and chondrocyte hypertrophy by targeting TLR3 and COL10A1 to alleviate osteoarthritis.
Qian Y, Chu G, Zhang L, Wu Z, Wang Q, Guo JJ, Zhou F
Journal of nanobiotechnology 2024 Feb 19;22(1):72
Journal of nanobiotechnology 2024 Feb 19;22(1):72
Maternal fiber-rich diet promotes early-life intestinal development in offspring through milk-derived extracellular vesicles carrying miR-146a-5p.
Lu D, Liu Y, Kang L, Zhang X, Hu J, Ye H, Huang B, Wu Y, Zhao J, Dai Z, Wang J, Han D
Journal of nanobiotechnology 2024 Feb 16;22(1):65
Journal of nanobiotechnology 2024 Feb 16;22(1):65
OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB.
Ma W, Sun Y, Yan R, Zhang P, Shen S, Lu H, Zhou Z, Jiang Z, Ye L, Mao Q, Xiong N, Jia W, Sun L, Gao P, Zhang H
Molecular cell 2024 Feb 1;84(3):538-551.e7
Molecular cell 2024 Feb 1;84(3):538-551.e7
Glutamine sensing licenses cholesterol synthesis.
Garcia BM, Melchinger P, Medeiros T, Hendrix S, Prabhu K, Corrado M, Kingma J, Gorbatenko A, Deshwal S, Veronese M, Scorrano L, Pearce E, Giavalisco P, Zelcer N, Pernas L
The EMBO journal 2024 Dec;43(23):5837-5856
The EMBO journal 2024 Dec;43(23):5837-5856
Novel injectable adhesive hydrogel loaded with exosomes for holistic repair of hemophilic articular cartilage defect.
Yang Q, Liu G, Chen G, Chen G, Chen K, Fan L, Tu Y, Chen J, Shi Z, Chen C, Liu S, Deng G, Deng X, Sun C, Li X, Yang S, Zheng S, Chen B
Bioactive materials 2024 Dec;42:85-111
Bioactive materials 2024 Dec;42:85-111
Tissue nano-transfection of antimicrobial genes drives bacterial biofilm killing in wounds and is potentially mediated by extracellular vesicles.
Cuellar-Gaviria TZ, Rincon-Benavides MA, Halipci Topsakal HN, Salazar-Puerta AI, Jaramillo-Garrido S, Kordowski M, Vasquez-Martinez CA, Nguyen KT, Rima XY, Rana PSJB, Combita-Heredia O, Deng B, Dathathreya K, McComb DW, Reategui E, Wozniak D, Higuita-Castro N, Gallego-Perez D
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:1300-1315
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:1300-1315
NEDD4L-mediated RASGRP2 suppresses high-glucose and oxLDL-induced vascular endothelial cell dysfunctions by activating Rap1 and R-Ras.
Chen G, Pei Y, Ye Q, Xie Z, Gyawali L, Liang X
Biochimica et biophysica acta. Molecular cell research 2024 Dec;1871(8):119844
Biochimica et biophysica acta. Molecular cell research 2024 Dec;1871(8):119844
Homozygous variant in translocase of outer mitochondrial membrane 7 leads to metabolic reprogramming and microcephalic osteodysplastic dwarfism with moyamoya disease.
Li CY, Chen LW, Tsai MC, Chou YY, Lin PX, Chang YM, Hwu WL, Chien YH, Lin JL, Chen HA, Lee NC, Su PH, Hsieh TC, Klinkhammer H, Wang YC, Huang YT, Krawitz PM, Lin SH, Huang LLH, Chiang PM, Shih MH, Chen PC
EBioMedicine 2024 Dec;110:105476
EBioMedicine 2024 Dec;110:105476
Immunomodulatory effect of mesenchymal stem cells-derived extracellular vesicles to modulate the regulatory T cells and Th1/Th2 imbalance in peripheral blood mononuclear cells of patients with allergic rhinitis.
Wang Z, Shahzad KA, Li X, Cai B, Xu M, Li J, Tan F
Scandinavian journal of immunology 2024 Dec;100(6):e13416
Scandinavian journal of immunology 2024 Dec;100(6):e13416
Opposing regulation of the STING pathway in hepatic stellate cells by NBR1 and p62 determines the progression of hepatocellular carcinoma.
Nishimura S, Linares JF, L'Hermitte A, Duran A, Cid-Diaz T, Martinez-Ordoñez A, Ruiz-Martinez M, Kudo Y, Marzio A, Heikenwalder M, Roberts LR, Diaz-Meco MT, Moscat J
Molecular cell 2024 Dec 5;84(23):4660-4676.e10
Molecular cell 2024 Dec 5;84(23):4660-4676.e10
Synthesis, anticancer and antibacterial evaluation of novel spiramycin-acylated derivatives.
Wang Z, Cheng J, Wen H, Hou T, Luo F, Wang Y, Xu X, Liu Y, Zhao Y, Liang X
RSC advances 2024 Dec 3;14(52):38898-38907
RSC advances 2024 Dec 3;14(52):38898-38907
The Microenvironment in an Experimental Model of Acute Pancreatitis Can Modify the Formation of the Protein Corona of sEVs, with Implications on Their Biological Function.
Armengol-Badia O, Maggi J, Casal C, Cortés R, Abián J, Carrascal M, Closa D
International journal of molecular sciences 2024 Dec 2;25(23)
International journal of molecular sciences 2024 Dec 2;25(23)
Adipose-derived stem cell exosomes attenuates myofibroblast transformation via inhibiting autophagy through TGF-β/Smad2 axis in oral submucosal fibrosis.
Xu J, Wang Y, Shao Z, Zhou Y, Bin X, Liu L, Huang W, Wang X, Hu Y, Li K
Journal of nanobiotechnology 2024 Dec 19;22(1):780
Journal of nanobiotechnology 2024 Dec 19;22(1):780
Osteoblast-derived exosomal miR-140-3p targets ACER2 and increases the progression of prostate cancer via the AKT/mTOR pathway-mediated inhibition of autophagy.
Liu Y, Chen S, Guo K, Ma S, Wang X, Liu Q, Yan R, Huang Y, Li T, He S, Hui J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70206
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70206
Ectopic endometrial stromal cell-derived extracellular vesicles encapsulating microRNA-25-3p induce endometrial collagen I deposition impairing decidualization in endometriosis.
Zhu Y, Zheng B, Zhang Y, Li M, Jiang Y, Zhou J, Zhang Y, Kang N, Wu M, Yan Y, Xing J, Zhou J
Molecular human reproduction 2024 Dec 11;30(12)
Molecular human reproduction 2024 Dec 11;30(12)
Functional multi-organelle units control inflammatory lipid metabolism of macrophages.
Zimmermann JA, Lucht K, Stecher M, Badhan C, Glaser KM, Epple MW, Koch LR, Deboutte W, Manke T, Ebnet K, Brinkmann F, Fehler O, Vogl T, Schuster EM, Bremser A, Buescher JM, Rambold AS
Nature cell biology 2024 Aug;26(8):1261-1273
Nature cell biology 2024 Aug;26(8):1261-1273
Circulating small extracellular vesicle RNA profiling for the detection of T1a stage colorectal cancer and precancerous advanced adenoma.
Min L, Bu F, Meng J, Liu X, Guo Q, Zhao L, Li Z, Li X, Zhu S, Zhang S
eLife 2024 Aug 9;12
eLife 2024 Aug 9;12
AGFG1 increases cholesterol biosynthesis by disrupting intracellular cholesterol homeostasis to promote PDAC progression.
Duan Z, Yang M, Yang J, Wu Z, Zhu Y, Jia Q, Ma X, Yin Y, Zheng J, Yang J, Jiang S, Hu L, Zhang J, Liu D, Huo Y, Yao L, Sun Y
Cancer letters 2024 Aug 28;598:217130
Cancer letters 2024 Aug 28;598:217130
Postprandial exercise regulates tissue-specific triglyceride uptake through angiopoietin-like proteins.
Liu X, Zhang Y, Han B, Li L, Li Y, Ma Y, Kang S, Li Q, Kong L, Huang K, Song BL, Liu Y, Wang Y
JCI insight 2024 Aug 22;9(16)
JCI insight 2024 Aug 22;9(16)
N-desmethyldauricine from Menispermum dauricum DC suppresses triple-negative breast cancer growth in 2D and 3D models by downregulating the NF-κB signaling pathway.
Liu W, Yu Y, Hou T, Wei H, Lv F, Shen A, Liu Y, Wang J, Fu D
Chemico-biological interactions 2024 Aug 1;398:111113
Chemico-biological interactions 2024 Aug 1;398:111113
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Zhao JL, Zhao L, Zhan QN, Liu M, Zhang T, Chu WW
Current medical science 2024 Apr;44(2):333-345
Current medical science 2024 Apr;44(2):333-345
Cerebrospinal fluid exosomal microRNAs as biomarkers for diagnosing or monitoring the progression of non-small cell lung cancer with leptomeningeal metastases.
Li H, Xia M, Zheng S, Lin Y, Yu T, Xie Y, Shen Y, Liu X, Qian X, Yin Z
Biotechnology & genetic engineering reviews 2024 Apr;40(1):359-380
Biotechnology & genetic engineering reviews 2024 Apr;40(1):359-380
Detecting early-warning biomarkers associated with heart-exosome genetic-signature for acute myocardial infarction: A source-tracking study of exosome.
Jin X, Xu W, Wu Q, Huang C, Song Y, Lian J
Journal of cellular and molecular medicine 2024 Apr;28(8):e18334
Journal of cellular and molecular medicine 2024 Apr;28(8):e18334
Cartilage stem/progenitor cells-derived exosomes facilitate knee cartilage repair in a subacute osteoarthritis rat model.
Chen J, Ni X, Yang J, Yang H, Liu X, Chen M, Sun C, Wang Y
Journal of cellular and molecular medicine 2024 Apr;28(8):e18327
Journal of cellular and molecular medicine 2024 Apr;28(8):e18327
Extracellular vesicles derived from M2-like macrophages alleviate acute lung injury in a miR-709-mediated manner.
Yang J, Huang X, Yu Q, Wang S, Wen X, Bai S, Cao L, Zhang K, Zhang S, Wang X, Chen Z, Cai Z, Zhang G
Journal of extracellular vesicles 2024 Apr;13(4):e12437
Journal of extracellular vesicles 2024 Apr;13(4):e12437
Perilipin membrane integration determines lipid droplet heterogeneity in differentiating adipocytes.
Majchrzak M, Stojanović O, Ajjaji D, Ben M'barek K, Omrane M, Thiam AR, Klemm RW
Cell reports 2024 Apr 23;43(4):114093
Cell reports 2024 Apr 23;43(4):114093
Zinc and manganese homeostasis closely interact in mammalian cells.
Nishito Y, Kamimura Y, Nagamatsu S, Yamamoto N, Yasui H, Kambe T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23605
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23605
Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis.
Zhang Q, Shen X, Yuan X, Huang J, Zhu Y, Zhu T, Zhang T, Wu H, Wu Q, Fan Y, Ni J, Meng L, He A, Shi C, Li H, Hu Q, Wang J, Chang C, Huang F, Li F, Chen M, Liu A, Ye S, Zheng M, Fang H
Nature communications 2024 Apr 13;15(1):3213
Nature communications 2024 Apr 13;15(1):3213
Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
Fang XX, Wei P, Zhao K, Sheng ZC, Song BL, Yin L, Luo J
The Journal of cell biology 2024 Apr 1;223(4)
The Journal of cell biology 2024 Apr 1;223(4)
Mesenchymal Stem Cell-Derived Exosomes Promote Recovery of The Facial Nerve Injury through Regulating Macrophage M1 and M2 Polarization by Targeting the P38 MAPK/NF-Κb Pathway.
Xue R, Xie M, Wu Z, Wang S, Zhang Y, Han Z, Li C, Tang Q, Wang L, Li D, Wang S, Yang H, Zhao RC
Aging and disease 2024 Apr 1;15(2):851-868
Aging and disease 2024 Apr 1;15(2):851-868
Common Markers and Small Molecule Inhibitors in Golgi Studies.
Bui S, Stark D, Li J, Zhang J, Wang Y
Methods in molecular biology (Clifton, N.J.) 2023;2557:453-493
Methods in molecular biology (Clifton, N.J.) 2023;2557:453-493
Immunofluorescence Microscopy of the Mammalian Golgi Apparatus.
Arab M, Nayak SC, Vitali T, Lowe M
Methods in molecular biology (Clifton, N.J.) 2023;2557:101-111
Methods in molecular biology (Clifton, N.J.) 2023;2557:101-111
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones.
Tao S, Yang EJ, Zong G, Mou PK, Ren G, Pu Y, Chen L, Kwon HJ, Zhou J, Hu Z, Khosravi A, Zhang Q, Du Y, Shi WQ, Shim JS
International journal of biological sciences 2023;19(13):4020-4035
International journal of biological sciences 2023;19(13):4020-4035
Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials.
Wang X, Hu S, Zhu D, Li J, Cheng K, Liu G
Nano research 2023;16(5):7248-7259
Nano research 2023;16(5):7248-7259
Identification of hsa-miR-619-5p and hsa-miR-4454 in plasma-derived exosomes as a potential biomarker for lung adenocarcinoma.
Feng L, Feng Z, Hu J, Gao J, Li A, He X, Liu L, Shen Z
Frontiers in genetics 2023;14:1138230
Frontiers in genetics 2023;14:1138230
Human umbilical cord mesenchymal stem cells derived extracellular vesicles alleviate salpingitis by promoting M1-to-M2 transformation.
Zhang C, Liao W, Li W, Li M, Xu X, Sun H, Xue Y, Liu L, Qiu J, Zhang C, Zhang X, Ye J, Du J, Deng DYB, Deng W, Li T
Frontiers in physiology 2023;14:1131701
Frontiers in physiology 2023;14:1131701
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution.
Chai C, Sui K, Tang J, Yu H, Yang C, Zhang H, Li SC, Zhong JF, Wang Z, Zhang X
Theranostics 2023;13(12):3943-3963
Theranostics 2023;13(12):3943-3963
MAVI1, an endoplasmic reticulum-localized microprotein, suppresses antiviral innate immune response by targeting MAVS on mitochondrion.
Shi TT, Huang Y, Li Y, Dai XL, He YH, Ding JC, Ran T, Shi Y, Yuan Q, Li WJ, Liu W
Science advances 2023 Sep;9(35):eadg7053
Science advances 2023 Sep;9(35):eadg7053
Novel neutrophil extracellular trap-related mechanisms in diabetic wounds inspire a promising treatment strategy with hypoxia-challenged small extracellular vesicles.
Chu Z, Huang Q, Ma K, Liu X, Zhang W, Cui S, Wei Q, Gao H, Hu W, Wang Z, Meng S, Tian L, Li H, Fu X, Zhang C
Bioactive materials 2023 Sep;27:257-270
Bioactive materials 2023 Sep;27:257-270
Amelioration of ethanol-induced oxidative stress and alcoholic liver disease by in vivo RNAi targeting Cyp2e1.
Wang Y, Chen Q, Wu S, Sun X, Yin R, Ouyang Z, Yin H, Wei Y
Acta pharmaceutica Sinica. B 2023 Sep;13(9):3906-3918
Acta pharmaceutica Sinica. B 2023 Sep;13(9):3906-3918
Fluorescence Tracking of Small Extracellular Vesicles In Vivo.
Chen Y, Shi Y, Tao Z
Pharmaceutics 2023 Sep 8;15(9)
Pharmaceutics 2023 Sep 8;15(9)
Enhanced wound healing and hemostasis with exosome-loaded gelatin sponges from human umbilical cord mesenchymal stem cells.
Hu XM, Wang CC, Xiao Y, Jiang P, Liu Y, Qi ZQ
World journal of stem cells 2023 Sep 26;15(9):947-959
World journal of stem cells 2023 Sep 26;15(9):947-959
FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson's disease via m6A-dependent regulation of ATM mRNA.
Geng Y, Long X, Zhang Y, Wang Y, You G, Guo W, Zhuang G, Zhang Y, Cheng X, Yuan Z, Zan J
Journal of translational medicine 2023 Sep 22;21(1):652
Journal of translational medicine 2023 Sep 22;21(1):652
Small RNA sequencing analysis of exosomes derived from umbilical plasma in IUGR lambs.
Lu J, Li H, Zheng X, Liu Y, Zhao P
Communications biology 2023 Sep 15;6(1):943
Communications biology 2023 Sep 15;6(1):943
The Exosome-Transmitted lncRNA LOC100132249 Induces Endothelial Dysfunction in Diabetic Retinopathy.
Hu Z, Wang J, Pan T, Li X, Tao C, Wu Y, Wang X, Zhang Z, Liu Y, Zhang W, Xu C, Wu X, Gu Q, Fan Y, Qian H, Mugisha A, Yuan S, Liu Q, Xie P
Diabetes 2023 Sep 1;72(9):1307-1319
Diabetes 2023 Sep 1;72(9):1307-1319
Proteomic Investigation of Differential Interactomes of Glypican 1 and a Putative Disease-Modifying Variant of Ataxia.
Cengiz Winter N, Karakaya M, Mosen P, Brusius I, Anlar B, Haliloglu G, Winter D, Wirth B
Journal of proteome research 2023 Sep 1;22(9):3081-3095
Journal of proteome research 2023 Sep 1;22(9):3081-3095
Lens epithelial cell-derived exosome inhibits angiogenesis in ocular pathological neovascularization through its delivery of miR-146a-5p.
Pan T, Wu Y, Zhang X, Wang J, Wang X, Gu Q, Xu C, Fan Y, Li X, Xie P, Liu Q, Hu Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23192
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23192
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
Zhang Y, Peng X, Xue M, Liu J, Shang G, Jiang M, Chen D, Liu B, Wang Y, Jia X, Xu J, Zhang F, Hu Y
Biogerontology 2023 Oct;24(5):813-827
Biogerontology 2023 Oct;24(5):813-827
Plasma extracellular vesicle long RNAs predict response to neoadjuvant immunotherapy and survival in patients with non-small cell lung cancer.
Guo W, Zhou B, Zhao L, Huai Q, Tan F, Xue Q, Lv F, Gao S, He J
Pharmacological research 2023 Oct;196:106921
Pharmacological research 2023 Oct;196:106921
Exosomes derived from human umbilical cord mesenchymal stem cells alleviate Parkinson's disease and neuronal damage through inhibition of microglia.
Zhang ZX, Zhou YJ, Gu P, Zhao W, Chen HX, Wu RY, Zhou LY, Cui QZ, Sun SK, Zhang LQ, Zhang K, Xu HJ, Chai XQ, An SJ
Neural regeneration research 2023 Oct;18(10):2291-2300
Neural regeneration research 2023 Oct;18(10):2291-2300
Single-cell dissection of cellular and molecular features underlying mesenchymal stem cell therapy in ischemic acute kidney injury.
Wang W, Zhang M, Ren X, Song Y, Xu Y, Zhuang K, Xiao T, Guo X, Wang S, Hong Q, Feng Z, Chen X, Cai G
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Oct 4;31(10):3067-3083
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Oct 4;31(10):3067-3083
PACS-2 deficiency aggravates tubular injury in diabetic kidney disease by inhibiting ER-phagy.
Yang J, Li L, Li C, Chen W, Liu Y, Luo S, Zhao C, Han Y, Yang M, Zhao H, Jiang N, Xi Y, Tang C, Cai J, Xiao L, Liu H, Sun L
Cell death & disease 2023 Oct 4;14(10):649
Cell death & disease 2023 Oct 4;14(10):649
Urinary exosome proteins PAK6 and EGFR as noninvasive diagnostic biomarkers of diabetic nephropathy.
Li T, Liu TC, Liu N, Li MJ, Zhang M
BMC nephrology 2023 Oct 3;24(1):291
BMC nephrology 2023 Oct 3;24(1):291
Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy.
Sun Y, Zheng H, Qian L, Liu Y, Zhu D, Xu Z, Chang W, Xu J, Wang L, Sun B, Gu L, Yuan H, Lou H
JACS Au 2023 Oct 23;3(10):2749-2762
JACS Au 2023 Oct 23;3(10):2749-2762
Manganese regulation of COPII condensation controls circulating lipid homeostasis.
Wang X, Huang R, Wang Y, Zhou W, Hu Y, Yao Y, Cheng K, Li X, Xu B, Zhang J, Xu Y, Zeng F, Zhu Y, Chen XW
Nature cell biology 2023 Nov;25(11):1650-1663
Nature cell biology 2023 Nov;25(11):1650-1663
CYP26B1-related disorder: expanding the ends of the spectrum through clinical and molecular evidence.
Silveira KC, Fonseca IC, Oborn C, Wengryn P, Ghafoor S, Beke A, Dreseris ES, Wong C, Iacovone A, Soltys CL, Babul-Hirji R, Artigalas O, Antolini-Tavares A, Gingras AC, Campos E, Cavalcanti DP, Kannu P
Human genetics 2023 Nov;142(11):1571-1586
Human genetics 2023 Nov;142(11):1571-1586
Prognostic and immunological role of cancer-associated fibroblasts-derived exosomal protein in esophageal squamous cell carcinoma.
Wang Z, Zhang M, Liu L, Yang Y, Qiu J, Yu Y, Li J
International immunopharmacology 2023 Nov;124(Pt A):110837
International immunopharmacology 2023 Nov;124(Pt A):110837
Heterozygous variants c.781G>A and c.1066dup of serine protease 56 cause familial nanophthalmos by impairing serine-type endopeptidase activity.
Wu W, Xu J, Yin H, Fu C, Yao K, Chen X
The British journal of ophthalmology 2023 Nov;107(11):1750-1756
The British journal of ophthalmology 2023 Nov;107(11):1750-1756
Role of a holo-insertase complex in the biogenesis of biophysically diverse ER membrane proteins.
Page KR, Nguyen VN, Pleiner T, Tomaleri GP, Wang ML, Guna A, Wang TY, Chou TF, Voorhees RM
bioRxiv : the preprint server for biology 2023 Nov 29;
bioRxiv : the preprint server for biology 2023 Nov 29;
Extracellular Vesicles and Their Renin-Angiotensin Cargo as a Link between Metabolic Syndrome and Parkinson's Disease.
Pedrosa MA, Labandeira CM, Lago-Baameiro N, Valenzuela R, Pardo M, Labandeira-Garcia JL, Rodriguez-Perez AI
Antioxidants (Basel, Switzerland) 2023 Nov 26;12(12)
Antioxidants (Basel, Switzerland) 2023 Nov 26;12(12)
STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons.
Serwach K, Nurowska E, Klukowska M, Zablocka B, Gruszczynska-Biegala J
Cellular and molecular life sciences : CMLS 2023 Nov 21;80(12):368
Cellular and molecular life sciences : CMLS 2023 Nov 21;80(12):368
Lymphocyte migration regulation related proteins in urine exosomes may serve as a potential biomarker for lung cancer diagnosis.
Jin S, Liu T, Wang W, Li T, Liu Z, Zhang M
BMC cancer 2023 Nov 18;23(1):1125
BMC cancer 2023 Nov 18;23(1):1125
PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation.
Inoue C, Mukai K, Matsudaira T, Nakayama J, Kono N, Aoki J, Arai H, Uchida Y, Taguchi T
Scientific reports 2023 Nov 13;13(1):19740
Scientific reports 2023 Nov 13;13(1):19740
ASTER-B regulates mitochondrial carotenoid transport and homeostasis.
Bandara S, Moon J, Ramkumar S, von Lintig J
Journal of lipid research 2023 May;64(5):100369
Journal of lipid research 2023 May;64(5):100369
Mesenchymal stem cells ameliorate cisplatin-induced acute kidney injury via let-7b-5p.
Wang SY, Xu Y, Hong Q, Chen XM, Cai GY
Cell and tissue research 2023 May;392(2):517-533
Cell and tissue research 2023 May;392(2):517-533
Plasma exosome-derived circGAPVD1 as a potential diagnostic marker for colorectal cancer.
Li T, Zhou T, Wu J, Lv H, Zhou H, Du M, Zhang X, Wu N, Gong S, Ren Z, Zhang P, Zhang C, Liu G, Liu X, Zhang Y
Translational oncology 2023 May;31:101652
Translational oncology 2023 May;31:101652
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
Ji Y, Luo Y, Wu Y, Sun Y, Zhao L, Xue Z, Sun M, Wei X, He Z, Wu SA, Lin LL, Lu Y, Chang L, Chen F, Chen S, Qian W, Xu X, Chen S, Pan D, Zhou Z, Xia S, Hu CA, Liang T, Qi L
Nature cell biology 2023 May;25(5):726-739
Nature cell biology 2023 May;25(5):726-739
M2 Macrophage-Derived sEV Regulate Pro-Inflammatory CCR2(+) Macrophage Subpopulations to Favor Post-AMI Cardiac Repair.
Li L, Cao J, Li S, Cui T, Ni J, Zhang H, Zhu Y, Mao J, Gao X, Midgley AC, Zhu M, Fan G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2202964
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2202964
Testicular exosomes disturb the immunosuppressive phenotype of testicular macrophages mediated by miR-155-5p in uropathogenic Escherichia coli-induced orchitis.
Xu J, He C, Fang YW, Hu ZY, Peng ML, Chen YY, Su YF, Liu CY, Zhang HP, Zhao K
Asian journal of andrology 2023 May-Jun;25(3):389-397
Asian journal of andrology 2023 May-Jun;25(3):389-397
ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer.
Yi J, Wang L, Du J, Wang M, Shen H, Liu Z, Qin Y, Liu J, Hu G, Xiao R, Ding J, Chen X, Wang H, Huang H, Ouyang G, Liu W
Developmental cell 2023 May 8;58(9):760-778.e6
Developmental cell 2023 May 8;58(9):760-778.e6
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Wu SA, Shen C, Wei X, Zhang X, Wang S, Chen X, Torres M, Lu Y, Lin LL, Wang HH, Hunter AH, Fang D, Sun S, Ivanova MI, Lin Y, Qi L
Nature communications 2023 May 30;14(1):3132
Nature communications 2023 May 30;14(1):3132
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Liu JL, Zhang L, Huang Y, Li XH, Liu YF, Zhang SM, Zhao YE, Chen XJ, Liu Y, He LY, Dong Z, Liu FY, Sun L, Xiao L
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Extracellular vesicle-mediated delivery of anti-miR-106b inhibits morphine-induced primary ciliogenesis in the brain.
Ma R, Kutchy NA, Wang Z, Hu G
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1332-1345
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1332-1345
Stress Granules Inhibit Coxsackievirus B3-Mediated Cell Death via Reduction of Mitochondrial Reactive Oxygen Species and Viral Extracellular Release.
Park JY, Shin OS
Journal of microbiology and biotechnology 2023 May 28;33(5):582-590
Journal of microbiology and biotechnology 2023 May 28;33(5):582-590
CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation.
Cheng J, Zhang G, Deng T, Liu Z, Zhang M, Zhang P, Adeshakin FO, Niu X, Yan D, Wan X, Yu G
Cell death & disease 2023 May 20;14(5):333
Cell death & disease 2023 May 20;14(5):333
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Xiao X, Shi J, He C, Bu X, Sun Y, Gao M, Xiang B, Xiong W, Dai P, Mao Q, Xing X, Yao Y, Yu H, Xu G, Li S, Ren Y, Chen B, Jiang C, Meng G, Lee YR, Wei W, Freeman GJ, Xie C, Zhang J
Nature communications 2023 May 19;14(1):2859
Nature communications 2023 May 19;14(1):2859
Extracellular Vesicles Released from Macrophages Infected with Mycoplasma pneumoniae Stimulate Proinflammatory Response via the TLR2-NF-κB/JNK Signaling Pathway.
Ma C, Hao X, Gao L, Wang Y, Shi J, Luo H, Li M
International journal of molecular sciences 2023 May 11;24(10)
International journal of molecular sciences 2023 May 11;24(10)
SERS spectroscopy with machine learning to analyze human plasma derived sEVs for coronary artery disease diagnosis and prognosis.
Huang X, Liu B, Guo S, Guo W, Liao K, Hu G, Shi W, Kuss M, Duryee MJ, Anderson DR, Lu Y, Duan B
Bioengineering & translational medicine 2023 Mar;8(2):e10420
Bioengineering & translational medicine 2023 Mar;8(2):e10420
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
Chen D, Jiang X, Zou H
Journal of orthopaedic translation 2023 Mar;39:163-176
Journal of orthopaedic translation 2023 Mar;39:163-176
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
Wu T, Zhu D, Wu X, Zhang N, Zhang Q
Oncology letters 2023 Mar;25(3):119
Oncology letters 2023 Mar;25(3):119
Proteomic Characterization of Peritoneal Extracellular Vesicles in a Mouse Model of Peritoneal Fibrosis.
Huang Q, Sun Y, Sun J, Peng L, Shang H, Wei D, Li C, Hu Z, Peng H
Journal of proteome research 2023 Mar 3;22(3):908-918
Journal of proteome research 2023 Mar 3;22(3):908-918
p130Cas is required for androgen-dependent postnatal development regulation of submandibular glands.
Gao J, Li A, Fujii S, Huang F, Nakatomi C, Nakamura I, Honda H, Kiyoshima T, Jimi E
Scientific reports 2023 Mar 29;13(1):5144
Scientific reports 2023 Mar 29;13(1):5144
Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps.
Wang T, Zhou Y, Zhou Z, Zhang P, Yan R, Sun L, Ma W, Zhang T, Shen S, Liu H, Lu H, Ye L, Feng J, Chen Z, Zhong X, Wu G, Cai Y, Jia W, Gao P, Zhang H
Nature communications 2023 Mar 18;14(1):1513
Nature communications 2023 Mar 18;14(1):1513
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Zhao F, Xu Y, Liu N, Lv D, Chen Y, Liu Z, Jin X, Xiao M, Lavillette D, Zhong J, Bartenschlager R, Long G
The EMBO journal 2023 Mar 15;42(6):e112096
The EMBO journal 2023 Mar 15;42(6):e112096
Tanshinone IIA enhances the therapeutic efficacy of mesenchymal stem cells derived exosomes in myocardial ischemia/reperfusion injury via up-regulating miR-223-5p.
Li S, Yang K, Cao W, Guo R, Liu Z, Zhang J, Fan A, Huang Y, Ma C, Li L, Fan G
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:13-26
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:13-26
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
Gong W, Guo Y, Yuan H, Chai R, Wan Z, Zheng B, Hu X, Chen B, Gao S, Dai Q, Yu P, Tu S
Cancer gene therapy 2023 Jun;30(6):905-916
Cancer gene therapy 2023 Jun;30(6):905-916
Exosomal microRNA‑4516, microRNA‑203 and SFRP1 are potential biomarkers of acute myocardial infarction.
Liu P, Wang S, Li K, Yang Y, Man Y, Du F, Wang L, Tian J, Su G
Molecular medicine reports 2023 Jun;27(6)
Molecular medicine reports 2023 Jun;27(6)
Circulating extracellular vesicles from patients with traumatic brain injury induce cerebrovascular endothelial dysfunction.
Li L, Li F, Bai X, Jia H, Wang C, Li P, Zhang Q, Guan S, Peng R, Zhang S, Dong JF, Zhang J, Xu X
Pharmacological research 2023 Jun;192:106791
Pharmacological research 2023 Jun;192:106791
miR-142-3p encapsulated in T lymphocyte-derived tissue small extracellular vesicles induces Treg function defect and thyrocyte destruction in Hashimoto's thyroiditis.
Li G, He L, Huang J, Liu J, Chen W, Zhong J, Wei T, Li Z, Zhu J, Lei J
BMC medicine 2023 Jun 6;21(1):206
BMC medicine 2023 Jun 6;21(1):206
Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury.
Yuan F, Peng W, Yang Y, Xu J, Liu Y, Xie Y, Huang T, Shi C, Ding Y, Li C, Qin T, Xie S, Zhu F, Lu H, Huang J, Hu J
Journal of neuroinflammation 2023 Jun 30;20(1):156
Journal of neuroinflammation 2023 Jun 30;20(1):156
TMEM41B Is an Interferon-Stimulated Gene That Promotes Pseudorabies Virus Replication.
Li XQ, Zeng L, Liang DG, Qi YL, Yang GY, Zhong K, Chu BB, Wang J
Journal of virology 2023 Jun 29;97(6):e0041223
Journal of virology 2023 Jun 29;97(6):e0041223
Lipid nanoparticle delivery of siRNA targeting Cyp2e1 gene attenuates subacute alcoholic liver injury in mice.
Wu S, Chen Q, Wang Y, Yin H, Wei Y
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 2023 Jun 25;52(3):306-317
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 2023 Jun 25;52(3):306-317
ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.
Sun Y, Zhu L, Liu P, Zhang H, Guo F, Jin X
Cancer research 2023 Jun 15;83(12):2034-2051
Cancer research 2023 Jun 15;83(12):2034-2051
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Deng M, He J, Hao C, Guo Y, Si H, Deng X, Zhang C, Li S, Yao S, Ren W, Yao W
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
Kong Y, Wu M, Wan X, Sun M, Zhang Y, Wu Z, Li C, Liang X, Gao L, Ma C, Yue X
Redox biology 2023 Jul;63:102732
Redox biology 2023 Jul;63:102732
Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies.
Guo L, Mao Q, He J, Liu X, Piao X, Luo L, Hao X, Yu H, Song Q, Xiao B, Fan D, Gao Z, Jia Y
Cell research 2023 Jul;33(7):497-515
Cell research 2023 Jul;33(7):497-515
Extracellular vesicle-packaged ILK from mesothelial cells promotes fibroblast activation in peritoneal fibrosis.
Huang Q, Sun Y, Peng L, Sun J, Sha Z, Lin H, Li Y, Li C, Li H, Shang H, Chen Y, Dou X, Hu Z, Ye Z, Peng H
Journal of extracellular vesicles 2023 Jul;12(7):e12334
Journal of extracellular vesicles 2023 Jul;12(7):e12334
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Lei Y, VanPortfliet JJ, Chen YF, Bryant JD, Li Y, Fails D, Torres-Odio S, Ragan KB, Deng J, Mohan A, Wang B, Brahms ON, Yates SD, Spencer M, Tong CW, Bosenberg MW, West LC, Shadel GS, Shutt TE, Upton JW, Li P, West AP
Cell 2023 Jul 6;186(14):3013-3032.e22
Cell 2023 Jul 6;186(14):3013-3032.e22
A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts.
Zhou M, Kong B, Zhang X, Xiao K, Lu J, Li W, Li M, Li Z, Ji W, Hou J, Xu T
iScience 2023 Jul 21;26(7):107159
iScience 2023 Jul 21;26(7):107159
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Yang S, Sun Y, Long M, Zhou X, Yuan M, Yang L, Luo W, Cheng Y, Zhang X, Jiang W, Chao J
Particle and fibre toxicology 2023 Jul 19;20(1):29
Particle and fibre toxicology 2023 Jul 19;20(1):29
Two microRNAs of plasma-derived small extracellular vesicles as biomarkers for metastatic non-small cell lung cancer.
Geng N, Qi Y, Qin W, Li S, Jin H, Jiang Y, Wang X, Wei S, Wang P
BMC pulmonary medicine 2023 Jul 14;23(1):259
BMC pulmonary medicine 2023 Jul 14;23(1):259
Changes in urinary exosomal protein CALM1 may serve as an early noninvasive biomarker for diagnosing diabetic kidney disease.
Li T, Ci Liu T, Liu N, Zhang M
Clinica chimica acta; international journal of clinical chemistry 2023 Jul 1;547:117466
Clinica chimica acta; international journal of clinical chemistry 2023 Jul 1;547:117466
Extracellular Vesicles from Carcinoma-associated Fibroblasts Promote EMT of Salivary Adenoid Cystic Carcinoma Via IL-6.
Al-Raimi HAI, Kong J, Ran Y, Zhu L, Li J, Liu X, Yang X, Qi D, Liu T
Archives of medical research 2023 Jan;54(1):27-36
Archives of medical research 2023 Jan;54(1):27-36
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions.
Chu Q, Wang J, Du Y, Zhou T, Shi A, Xiong J, Ji WK, Deng L
Cell death and differentiation 2023 Jan;30(1):94-110
Cell death and differentiation 2023 Jan;30(1):94-110
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
Liu D, Li X, Zeng B, Zhao Q, Chen H, Zhang Y, Chen Y, Wang J, Xing HR
Stem cell reviews and reports 2023 Jan;19(1):155-169
Stem cell reviews and reports 2023 Jan;19(1):155-169
Low-intensity pulsed ultrasound (LIPUS) enhances the anti-inflammatory effects of bone marrow mesenchymal stem cells (BMSCs)-derived extracellular vesicles.
Li X, Zhong Y, Zhou W, Song Y, Li W, Jin Q, Gao T, Zhang L, Xie M
Cellular & molecular biology letters 2023 Jan 30;28(1):9
Cellular & molecular biology letters 2023 Jan 30;28(1):9
miR-150-5p in neutrophil-derived extracellular vesicles associated with sepsis-induced cardiomyopathy in septic patients.
Ye R, Lin Q, Xiao W, Mao L, Zhang P, Zhou L, Wu X, Jiang N, Zhang X, Zhang Y, Ma D, Huang J, Wang X, Deng L
Cell death discovery 2023 Jan 21;9(1):19
Cell death discovery 2023 Jan 21;9(1):19
A RIPK3-independent role of MLKL in suppressing parthanatos promotes immune evasion in hepatocellular carcinoma.
Jiang X, Deng W, Tao S, Tang Z, Chen Y, Tian M, Wang T, Tao C, Li Y, Fang Y, Pu C, Gao J, Wang X, Qu W, Gai X, Ding Z, Fu Y, Zheng Y, Cao S, Zhou J, Huang M, Liu W, Xu J, Fan J, Shi Y
Cell discovery 2023 Jan 17;9(1):7
Cell discovery 2023 Jan 17;9(1):7
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Wang J, Xu J, Dong Y, Su Z, Su H, Cheng Q, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Zou X, Liao Y, Liu Z, Xu X, Sun W, Qin H, Wang H, Liu J, Jing T
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
Ye Z, Xiong Y, Peng W, Wei W, Huang L, Yue J, Zhang C, Lin G, Huang F, Zhang L, Zheng S, Yue J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.
Ganji R, Paulo JA, Xi Y, Kline I, Zhu J, Clemen CS, Weihl CC, Purdy JG, Gygi SP, Raman M
Nature communications 2023 Feb 6;14(1):638
Nature communications 2023 Feb 6;14(1):638
Mesenchymal stem cells-derived exosomes ameliorate high glucose and lipopolysaccharide-induced HPMECs injury through the Nrf2/HO-1 pathway.
Sun H, Lu S, Qu G, Li J, Song B
Autoimmunity 2023 Dec;56(1):2290357
Autoimmunity 2023 Dec;56(1):2290357
Integrated transcriptomics, proteomics, and functional analysis to characterize the tissue-specific small extracellular vesicle network of breast cancer.
Shen L, Huang H, Wei Z, Chen W, Li J, Yao Y, Zhou J, Liu J, Sun S, Xia W, Zhang T, Yu X, Shen J, Wang W, Jiang J, Huang J, Jiang M, Ni C
MedComm 2023 Dec;4(6):e433
MedComm 2023 Dec;4(6):e433
Negatively charged bladder acellular matrix loaded with positively charged adipose-derived mesenchymal stem cell-derived small extracellular vesicles for bladder tissue engineering.
Yang T, Zhao F, Zhao J, Geng J, Shao C, Liu J, Sheng F, Zhou L, Xu H, Jia R
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:718-733
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:718-733
SARS-CoV-2 papain-like protease plays multiple roles in regulating cellular proteins in the endoplasmic reticulum.
Yang M, Mariano J, Su R, Smith CE, Das S, Gill C, Andresson T, Loncarek J, Tsai YC, Weissman AM
The Journal of biological chemistry 2023 Dec;299(12):105346
The Journal of biological chemistry 2023 Dec;299(12):105346
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism.
Sun L, Suo C, Zhang T, Shen S, Gu X, Qiu S, Zhang P, Wei H, Ma W, Yan R, Chen R, Jia W, Cao J, Zhang H, Gao P
Nature chemical biology 2023 Dec;19(12):1492-1503
Nature chemical biology 2023 Dec;19(12):1492-1503
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10.
Liu X, Jin S, Liu J, Xu X
Acta histochemica 2023 Dec;125(8):152102
Acta histochemica 2023 Dec;125(8):152102
Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization.
Yao Y, Chen C, Wang J, Xuan H, Chen X, Li Z, Yang F, Wang B, Lin S, Li S, Tang D, Gong L, Gao W
Journal of experimental & clinical cancer research : CR 2023 Dec 5;42(1):330
Journal of experimental & clinical cancer research : CR 2023 Dec 5;42(1):330
Extracellular vesicles long RNA profiling identifies abundant mRNA, circRNA and lncRNA in human bile as potential biomarkers for cancer diagnosis.
Zong H, Yu W, Lai H, Chen B, Zhang H, Zhao J, Huang S, Li Y
Carcinogenesis 2023 Dec 2;44(8-9):671-681
Carcinogenesis 2023 Dec 2;44(8-9):671-681
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Bao H, Peng Z, Cheng X, Jian C, Li X, Shi Y, Zhu W, Hu Y, Jiang M, Song J, Fang F, Chen J, Shu X
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
MiR-146b-5p enriched bioinspired exosomes derived from fucoidan-directed induction mesenchymal stem cells protect chondrocytes in osteoarthritis by targeting TRAF6.
Lou C, Jiang H, Lin Z, Xia T, Wang W, Lin C, Zhang Z, Fu H, Iqbal S, Liu H, Lin J, Wang J, Pan X, Xue X
Journal of nanobiotechnology 2023 Dec 18;21(1):486
Journal of nanobiotechnology 2023 Dec 18;21(1):486
ARRDC5 deficiency impairs spermatogenesis by affecting SUN5 and NDC1.
Liu R, Qu R, Li Q, Chen B, Mu J, Zeng Y, Luo Y, Xu F, Wang L, Zhang Z, Sang Q
Development (Cambridge, England) 2023 Dec 15;150(24)
Development (Cambridge, England) 2023 Dec 15;150(24)
Cultured lymphocytes' mitochondrial genome integrity is not altered by cladribine.
Järvinen E, Suomi F, Stewart JB, Guala D, Valori M, Jansson L, Nieminen J, McWilliams TG, Tienari PJ
Clinical and experimental immunology 2023 Dec 13;214(3):304-313
Clinical and experimental immunology 2023 Dec 13;214(3):304-313
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.
Huang J, Ding M, Lu Y, Xu L, Zhang Y, Han S, Zhu X, Li Y, Chen P
Cell death & disease 2023 Dec 1;14(12):789
Cell death & disease 2023 Dec 1;14(12):789
Engineered Extracellular Vesicle-Based Therapies for Valvular Heart Disease.
Salazar-Puerta AI, Kordowski M, Cuellar-Gaviria TZ, Rincon-Benavides MA, Hussein J, Flemister D, Mayoral-Andrade G, Barringer G, Guilfoyle E, Blackstone BN, Deng B, Zepeda-Orozco D, McComb DW, Powell H, Dasi LP, Gallego-Perez D, Higuita-Castro N
Cellular and molecular bioengineering 2023 Aug;16(4):309-324
Cellular and molecular bioengineering 2023 Aug;16(4):309-324
The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity.
Chen T, Feng Y, Sun W, Zhao G, Wu H, Cheng X, Zhao F, Zhang L, Zheng Y, Zhan P, Zhao W, Liu B, Gao C
Immunity 2023 Aug 8;56(8):1727-1742.e6
Immunity 2023 Aug 8;56(8):1727-1742.e6
Tumor-Associated Extracellular Microvesicles with Fluorine-Modified Carbohydrate Antigens Trigger a Stronger Antitumor Immune Response.
Mo J, Zou Y, Li BH, Li G, Zheng XJ, Liu Y, Ye XS
ACS applied materials & interfaces 2023 Aug 30;15(34):40201-40212
ACS applied materials & interfaces 2023 Aug 30;15(34):40201-40212
Carcinoma-associated fibroblast-derived lysyl oxidase-rich extracellular vesicles mediate collagen crosslinking and promote epithelial-mesenchymal transition via p-FAK/p-paxillin/YAP signaling.
Liu X, Li J, Yang X, Li X, Kong J, Qi D, Zhang F, Sun B, Liu Y, Liu T
International journal of oral science 2023 Aug 2;15(1):32
International journal of oral science 2023 Aug 2;15(1):32
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
Shi J, Wang W, Sun S, Xu X, Fei J, Zhou Q, Qin C, Ou S, Wu F, Wu FT, Xu T, Bai L, Xie F
iScience 2023 Aug 18;26(8):107312
iScience 2023 Aug 18;26(8):107312
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, Geng G, Mu C, Chen L, Liu Q, Luo Q, Zhang C, Long Y, Su J, Wang Y, Li Z, Sun J, Chen G, Li Y, Liao X, Shang Y, Hu G, Chen Q, Zhu Y
The EMBO journal 2023 Aug 15;42(16):e113258
The EMBO journal 2023 Aug 15;42(16):e113258
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Wang J, Cheng Q, Zhang Y, Hong C, Liu J, Liu X, Chang J
Aging and disease 2023 Aug 1;14(4):1458-1471
Aging and disease 2023 Aug 1;14(4):1458-1471
ARF6 plays a general role in targeting palmitoylated proteins from the Golgi to the plasma membrane.
Wang J, Zheng LF, Ren S, Li DL, Chen C, Sun HH, Liu LY, Guo H, Zhao TJ
Journal of cell science 2023 Aug 1;136(15)
Journal of cell science 2023 Aug 1;136(15)
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Qiu S, Zhong X, Meng X, Li S, Qian X, Lu H, Cai J, Zhang Y, Wang M, Ye Z, Zhang H, Gao P
Cell research 2023 Apr;33(4):299-311
Cell research 2023 Apr;33(4):299-311
Exosomes incorporated with black phosphorus quantum dots attenuate retinal angiogenesis via disrupting glucose metabolism.
Gui X, Zhang H, Zhang R, Li Q, Zhu W, Nie Z, Zhao J, Cui X, Hao W, Wen X, Shen W, Song H
Materials today. Bio 2023 Apr;19:100602
Materials today. Bio 2023 Apr;19:100602
MicroRNA-19b-3p dysfunction of mesenchymal stem cell-derived exosomes from patients with abdominal aortic aneurysm impairs therapeutic efficacy.
Zhang Y, Huang X, Sun T, Shi L, Liu B, Hong Y, Fu QL, Zhang Y, Li X
Journal of nanobiotechnology 2023 Apr 26;21(1):135
Journal of nanobiotechnology 2023 Apr 26;21(1):135
Pharmacological chaperones restore proteostasis of epilepsy-associated GABA(A) receptor variants.
Wang YJ, Seibert H, Ahn LY, Schaffer AE, Mu TW
bioRxiv : the preprint server for biology 2023 Apr 19;
bioRxiv : the preprint server for biology 2023 Apr 19;
Pigmentation and TYRP1 expression are mediated by zinc through the early secretory pathway-resident ZNT proteins.
Wagatsuma T, Suzuki E, Shiotsu M, Sogo A, Nishito Y, Ando H, Hashimoto H, Petris MJ, Kinoshita M, Kambe T
Communications biology 2023 Apr 18;6(1):403
Communications biology 2023 Apr 18;6(1):403
Phenylethanoid glycosides extract from Cistanche deserticola ameliorates atherosclerosis in apolipoprotein E-deficient mice and regulates intestinal PPARγ-LXRα-ABCA1 pathway.
Jia X, Liu B, Xue J, Liu Y, Zhang J, Qin S, Zhang Y
The Journal of pharmacy and pharmacology 2023 Apr 17;75(5):677-685
The Journal of pharmacy and pharmacology 2023 Apr 17;75(5):677-685
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Lu J, Yang X, He C, Chen Y, Li C, Li S, Chen Y, Wu Y, Xiang Z, Kang J, Jiang G, Wang C, Diarra MD, He R, Feng G, Yan R
Acta biomaterialia 2023 Apr 15;161:80-99
Acta biomaterialia 2023 Apr 15;161:80-99
Signal-Retaining Autophagy Indicator as a Quantitative Imaging Method for ER-Phagy.
Jimenez-Moreno N, Salomo-Coll C, Murphy LC, Wilkinson S
Cells 2023 Apr 11;12(8)
Cells 2023 Apr 11;12(8)
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Geng J, Khaket TP, Pan J, Li W, Zhang Y, Ping Y, Cobos Sillero MI, Lu B
Developmental cell 2023 Apr 10;58(7):597-615.e10
Developmental cell 2023 Apr 10;58(7):597-615.e10
Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.
Wang S, Shi M, Zhou J, Wang W, Zhang Y, Li Y
Frontiers in cardiovascular medicine 2022;9:844047
Frontiers in cardiovascular medicine 2022;9:844047
miR-29a-3p in Exosomes from Heme Oxygenase-1 Modified Bone Marrow Mesenchymal Stem Cells Alleviates Steatotic Liver Ischemia-Reperfusion Injury in Rats by Suppressing Ferroptosis via Iron Responsive Element Binding Protein 2.
Li X, Wu L, Tian X, Zheng W, Yuan M, Tian X, Zuo H, Song H, Shen Z
Oxidative medicine and cellular longevity 2022;2022:6520789
Oxidative medicine and cellular longevity 2022;2022:6520789
Intraneuronal sortilin aggregation relative to granulovacuolar degeneration, tau pathogenesis and sorfra plaque formation in human hippocampal formation.
Jiang J, Yang C, Ai JQ, Zhang QL, Cai XL, Tu T, Wan L, Wang XS, Wang H, Pan A, Manavis J, Gai WP, Che C, Tu E, Wang XP, Li ZY, Yan XX
Frontiers in aging neuroscience 2022;14:926904
Frontiers in aging neuroscience 2022;14:926904
The potential role of exosomal miRNAs and membrane proteins in acute HIV-infected people.
Li X, Wang W, Chen J, Xie B, Luo S, Chen D, Cai C, Li C, Li W
Frontiers in immunology 2022;13:939504
Frontiers in immunology 2022;13:939504
Extracellular Vesicle-Mediated Delivery of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles to Mice Brain.
Kutchy NA, Ma R, Liu Y, Buch S, Hu G
Frontiers in pharmacology 2022;13:819516
Frontiers in pharmacology 2022;13:819516
Characterization and subcellular localization of Alongshan virus proteins.
Zhao Y, Wu P, Liu L, Ma B, Pan M, Huang Y, Du N, Yu H, Sui L, Wang ZD, Hou Z, Liu Q
Frontiers in microbiology 2022;13:1000322
Frontiers in microbiology 2022;13:1000322
Exosomal CD44 Transmits Lymph Node Metastatic Capacity Between Gastric Cancer Cells via YAP-CPT1A-Mediated FAO Reprogramming.
Wang M, Yu W, Cao X, Gu H, Huang J, Wu C, Wang L, Sha X, Shen B, Wang T, Yao Y, Zhu W, Huang F
Frontiers in oncology 2022;12:860175
Frontiers in oncology 2022;12:860175
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Liang S, Zhu C, Suo C, Wei H, Yu Y, Gu X, Chen L, Yuan M, Shen S, Li S, Sun L, Gao P
Frontiers in oncology 2022;12:857968
Frontiers in oncology 2022;12:857968
Hypoxic Cell-Derived Extracellular Vesicles Aggravate Rectal Injury Following Radiotherapy via MiR-122-5p.
Xu Y, Ge Y, Chen X, Zhang Y, Chen H, Liu D, Lu Y, Liu Y, Tu W
Frontiers in cell and developmental biology 2022;10:892575
Frontiers in cell and developmental biology 2022;10:892575
The activity of disease-causative STING variants can be suppressed by wild-type STING through heterocomplex formation.
Shindo R, Kuchitsu Y, Mukai K, Taguchi T
Frontiers in cell and developmental biology 2022;10:1037999
Frontiers in cell and developmental biology 2022;10:1037999
Phospholipid peroxidation inhibits autophagy via stimulating the delipidation of oxidized LC3-PE.
Li W, Luo LX, Zhou QQ, Gong HB, Fu YY, Yan CY, Li E, Sun J, Luo Z, Ding ZJ, Zhang QY, Mu HL, Cao YF, Ouyang SH, Kurihara H, Li YF, Sun WY, Li M, He RR
Redox biology 2022 Sep;55:102421
Redox biology 2022 Sep;55:102421
Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.
Khodayari N, Oshins R, Mehrad B, Lascano JE, Qiang X, West JR, Holliday LS, Lee J, Wiesemann G, Eydgahi S, Brantly M
Respiratory research 2022 Sep 6;23(1):232
Respiratory research 2022 Sep 6;23(1):232
De novo sphingolipid biosynthesis necessitates detoxification in cancer cells.
Spears ME, Lee N, Hwang S, Park SJ, Carlisle AE, Li R, Doshi MB, Armando AM, Gao J, Simin K, Zhu LJ, Greer PL, Quehenberger O, Torres EM, Kim D
Cell reports 2022 Sep 27;40(13):111415
Cell reports 2022 Sep 27;40(13):111415
TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.
Wang L, Li J, Wang Q, Ge MX, Ji J, Liu D, Wang Z, Cao Y, Zhang Y, Zhang ZR
Molecular cell 2022 Sep 15;82(18):3453-3467.e14
Molecular cell 2022 Sep 15;82(18):3453-3467.e14
TMEΜ45B Interacts with Sindbis Virus Nsp1 and Nsp4 and Inhibits Viral Replication.
Yan F, Yang W, Wang X, Gao G
Journal of virology 2022 Sep 14;96(17):e0091922
Journal of virology 2022 Sep 14;96(17):e0091922
TMEM63C mutations cause mitochondrial morphology defects and underlie hereditary spastic paraplegia.
Tábara LC, Al-Salmi F, Maroofian R, Al-Futaisi AM, Al-Murshedi F, Kennedy J, Day JO, Courtin T, Al-Khayat A, Galedari H, Mazaheri N, Protasoni M, Johnson M, Leslie JS, Salter CG, Rawlins LE, Fasham J, Al-Maawali A, Voutsina N, Charles P, Harrold L, Keren B, Kunji ERS, Vona B, Jelodar G, Sedaghat A, Shariati G, Houlden H, Crosby AH, Prudent J, Baple EL
Brain : a journal of neurology 2022 Sep 14;145(9):3095-3107
Brain : a journal of neurology 2022 Sep 14;145(9):3095-3107
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Li GN, Zhao XJ, Wang Z, Luo MS, Shi SN, Yan DM, Li HY, Liu JH, Yang Y, Tan JH, Zhang ZY, Chen RQ, Lai HL, Huang XY, Zhou JF, Ma D, Fang Y, Gao QL
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Aberrant Cholesterol Metabolism and Wnt/β-Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth.
Zheng S, Lin J, Pang Z, Zhang H, Wang Y, Ma L, Zhang H, Zhang X, Chen M, Zhang X, Zhao C, Qi J, Cao L, Wang M, He X, Sheng R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(28):e2200750
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(28):e2200750
The role of hepatic Surf4 in lipoprotein metabolism and the development of atherosclerosis in apoE(-/-) mice.
Shen Y, Gu HM, Zhai L, Wang B, Qin S, Zhang DW
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Oct;1867(10):159196
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Oct;1867(10):159196
The delivery of miR-21a-5p by extracellular vesicles induces microglial polarization via the STAT3 pathway following hypoxia-ischemia in neonatal mice.
Xin DQ, Zhao YJ, Li TT, Ke HF, Gai CC, Guo XF, Chen WQ, Liu DX, Wang Z
Neural regeneration research 2022 Oct;17(10):2238-2246
Neural regeneration research 2022 Oct;17(10):2238-2246
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.
Wang R, Shang Y, Chen B, Xu F, Zhang J, Zhang Z, Zhao X, Wan X, Xu A, Wu L, Zhao G
Cell death & disease 2022 Oct 6;13(10):851
Cell death & disease 2022 Oct 6;13(10):851
Mutated lncRNA increase the risk of type 2 diabetes by promoting β cell dysfunction and insulin resistance.
Guo WH, Guo Q, Liu YL, Yan DD, Jin L, Zhang R, Yan J, Luo XH, Yang M
Cell death & disease 2022 Oct 27;13(10):904
Cell death & disease 2022 Oct 27;13(10):904
Extracellular vesicles derived from endometrial epithelial cells deliver exogenous miR-92b-3p to affect the function of embryonic trophoblast cells via targeting TSC1 and DKK3.
Hua R, Liu Q, Lian W, Kang TT, Gao D, Huang C, Wang Y, Lei M
Reproductive biology and endocrinology : RB&E 2022 Oct 25;20(1):152
Reproductive biology and endocrinology : RB&E 2022 Oct 25;20(1):152
Extracellular Vesicles Secreted by Mouse Decidual Cells Carry Critical Information for the Establishment of Pregnancy.
Ma Q, Beal JR, Song X, Bhurke A, Bagchi IC, Bagchi MK
Endocrinology 2022 Oct 23;163(12)
Endocrinology 2022 Oct 23;163(12)
Proteomic and miRNA Profiles of Exosomes Derived from Myometrial Tissue in Laboring Women.
Deng W, Wang X, Chen L, Wen B, Chen Y, Ji K, Liu H
International journal of molecular sciences 2022 Oct 15;23(20)
International journal of molecular sciences 2022 Oct 15;23(20)
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
Li X, Liu D, Chen H, Zeng B, Zhao Q, Zhang Y, Chen Y, Wang J, Xing HR
Biological research 2022 Oct 1;55(1):29
Biological research 2022 Oct 1;55(1):29
SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.
Han L, Zheng Y, Deng J, Nan ML, Xiao Y, Zhuang MW, Zhang J, Wang W, Gao C, Wang PH
Journal of medical virology 2022 Nov;94(11):5174-5188
Journal of medical virology 2022 Nov;94(11):5174-5188
Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.
Strohm L, Hu Z, Suk Y, Rühmkorf A, Sternburg E, Gattringer V, Riemenschneider H, Berutti R, Graf E, Weishaupt JH, Brill MS, Harbauer AB, Dormann D, Dengjel J, Edbauer D, Behrends C
Life science alliance 2022 Nov;5(11)
Life science alliance 2022 Nov;5(11)
SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection.
Zhang X, Yang Z, Pan T, Long X, Sun Q, Wang PH, Li X, Kuang E
Autophagy 2022 Nov;18(11):2576-2592
Autophagy 2022 Nov;18(11):2576-2592
Extracellular vesicles from human urine-derived stem cells merged in hyaluronic acid ameliorate erectile dysfunction in type 2 diabetic rats by glans administration.
Zhuang J, Gao P, Chen H, Fang Z, Zheng J, Zhu D, Hou J
Andrology 2022 Nov;10(8):1673-1686
Andrology 2022 Nov;10(8):1673-1686
Plasma Extracellular Vesicle Long RNA in Diagnosis and Prediction in Small Cell Lung Cancer.
Liu C, Chen J, Liao J, Li Y, Yu H, Zhao X, Sun S, Hu Z, Zhang Y, Zhu Z, Fan M, Huang S, Wang J
Cancers 2022 Nov 9;14(22)
Cancers 2022 Nov 9;14(22)
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1.
Cen X, Chen Q, Wang B, Xu H, Wang X, Ling Y, Zhang X, Qin D
Cell communication and signaling : CCS 2022 Nov 28;20(1):191
Cell communication and signaling : CCS 2022 Nov 28;20(1):191
Extracellular vesicle-derived long non-coding RNA as circulating biomarkers for endometriosis.
Shan S, Yang Y, Jiang J, Yang B, Yang Y, Sun F, Zhang J, Lin Y, Xu H
Reproductive biomedicine online 2022 May;44(5):923-933
Reproductive biomedicine online 2022 May;44(5):923-933
The endoplasmic reticulum adopts two distinct tubule forms.
Wang B, Zhao Z, Xiong M, Yan R, Xu K
Proceedings of the National Academy of Sciences of the United States of America 2022 May 3;119(18):e2117559119
Proceedings of the National Academy of Sciences of the United States of America 2022 May 3;119(18):e2117559119
Autophagic LC3(+) calcified extracellular vesicles initiate cartilage calcification in osteoarthritis.
Yan J, Shen M, Sui B, Lu W, Han X, Wan Q, Liu Y, Kang J, Qin W, Zhang Z, Chen D, Cao Y, Ying S, Tay FR, Niu LN, Jiao K
Science advances 2022 May 13;8(19):eabn1556
Science advances 2022 May 13;8(19):eabn1556
Evaluation of plasma exosomal miRNAs as potential diagnostic biomarkers of lymph node metastasis in papillary thyroid carcinoma.
Chen W, Li G, Li Z, Zhu J, Wei T, Lei J
Endocrine 2022 Mar;75(3):846-855
Endocrine 2022 Mar;75(3):846-855
Photobiomodulation promotes hair regeneration in injured skin by enhancing migration and exosome secretion of dermal papilla cells.
Zhang Y, Su J, Ma K, Li H, Fu X, Zhang C
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2022 Mar;30(2):245-257
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2022 Mar;30(2):245-257
Human Cytomegalovirus Hijacks WD Repeat Domain 11 for Virion Assembly Compartment Formation and Virion Morphogenesis.
Yang B, Yao Y, Cheng H, Wang XZ, Zhou YP, Huang SN, Ma X, Yang H, Wu J, Jiang X, Cheng S, Sun JY, Zeng WB, Chen J, Zhang FK, Shen HJ, Gu JY, McVoy MA, Britt WJ, Gong S, Luo MH
Journal of virology 2022 Mar 9;96(5):e0182721
Journal of virology 2022 Mar 9;96(5):e0182721
ESCRT dysfunction compromises endoplasmic reticulum maturation and autophagosome biogenesis in Drosophila.
Wang R, Miao G, Shen JL, Fortier TM, Baehrecke EH
Current biology : CB 2022 Mar 28;32(6):1262-1274.e4
Current biology : CB 2022 Mar 28;32(6):1262-1274.e4
ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.
Zhao Y, Hu D, Wang R, Sun X, Ropelewski P, Hubler Z, Lundberg K, Wang Q, Adams DJ, Xu R, Qi X
Nature communications 2022 Mar 2;13(1):1121
Nature communications 2022 Mar 2;13(1):1121
N-terminome analyses underscore the prevalence of SPPL3-mediated intramembrane proteolysis among Golgi-resident enzymes and its role in Golgi enzyme secretion.
Hobohm L, Koudelka T, Bahr FH, Truberg J, Kapell S, Schacht SS, Meisinger D, Mengel M, Jochimsen A, Hofmann A, Heintz L, Tholey A, Voss M
Cellular and molecular life sciences : CMLS 2022 Mar 13;79(3):185
Cellular and molecular life sciences : CMLS 2022 Mar 13;79(3):185
MOSPD2 is an endoplasmic reticulum-lipid droplet tether functioning in LD homeostasis.
Zouiouich M, Di Mattia T, Martinet A, Eichler J, Wendling C, Tomishige N, Grandgirard E, Fuggetta N, Fromental-Ramain C, Mizzon G, Dumesnil C, Carpentier M, Reina-San-Martin B, Mathelin C, Schwab Y, Thiam AR, Kobayashi T, Drin G, Tomasetto C, Alpy F
The Journal of cell biology 2022 Jun 6;221(6)
The Journal of cell biology 2022 Jun 6;221(6)
Preparation of Recombinant Human Collagen III Protein Hydrogels with Sustained Release of Extracellular Vesicles for Skin Wound Healing.
Xu L, Liu Y, Tang L, Xiao H, Yang Z, Wang S
International journal of molecular sciences 2022 Jun 3;23(11)
International journal of molecular sciences 2022 Jun 3;23(11)
Micro-RNAs from Plasma-Derived Small Extracellular Vesicles as Potential Biomarkers for Tic Disorders Diagnosis.
Wang Y, Xu X, Chen H, Zhu M, Guo X, Gao F
Brain sciences 2022 Jun 26;12(7)
Brain sciences 2022 Jun 26;12(7)
Exosomal tRF-Leu-AAG-001 derived from mast cell as a potential non-invasive diagnostic biomarker for endometriosis.
Li Y, Cui S, Xu Z, Zhang Y, Wu T, Zhang J, Chen Y
BMC women's health 2022 Jun 25;22(1):253
BMC women's health 2022 Jun 25;22(1):253
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Yan JM, Zhang WK, Yan LN, Jiao YJ, Zhou CM, Yu XJ
Autophagy 2022 Jul;18(7):1599-1612
Autophagy 2022 Jul;18(7):1599-1612
Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation.
Chen P, Tang S, Gao H, Zhang H, Chen C, Fang Z, Peng G, Weng H, Chen A, Zhang C, Qiu Z, Li S, Chen J, Chen L, Chen X
International journal of pharmaceutics 2022 Jul 25;623:121952
International journal of pharmaceutics 2022 Jul 25;623:121952
FAM69C, a kinase critical for synaptic function and memory, is defective in neurodegenerative dementia.
Mei F, Hu J, Wu Z, Zhang G, Liu A, Li X, Zhu M, Gan Y, Liang L, Zhao X, Yuan Y, Meng X, Li Y, Jin Y, Jia J, Yin Y
Cell reports 2022 Jul 19;40(3):111101
Cell reports 2022 Jul 19;40(3):111101
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
Zhou H, Shen X, Yan C, Xiong W, Ma Z, Tan Z, Wang J, Li Y, Liu J, Duan A, Liu F
Stem cell research & therapy 2022 Jul 16;13(1):322
Stem cell research & therapy 2022 Jul 16;13(1):322
The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice.
Nozawa K, Fujihara Y, Devlin DJ, Deras RE, Kent K, Larina IV, Umezu K, Yu Z, Sutton CM, Ye Q, Dean LK, Emori C, Ikawa M, Garcia TX, Matzuk MM
BMC biology 2022 Jul 13;20(1):161
BMC biology 2022 Jul 13;20(1):161
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
Chen B, Qin G, Xiao J, Deng X, Lin A, Liu H
Journal of neuroinflammation 2022 Jul 13;19(1):181
Journal of neuroinflammation 2022 Jul 13;19(1):181
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li ST, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H
Nature cancer 2022 Jan;3(1):75-89
Nature cancer 2022 Jan;3(1):75-89
Inflammatory capacity of exosomes released in the early stages of acute pancreatitis predicts the severity of the disease.
Carrascal M, Areny-Balagueró A, de-Madaria E, Cárdenas-Jaén K, García-Rayado G, Rivera R, Martin Mateos RM, Pascual-Moreno I, Gironella M, Abian J, Closa D
The Journal of pathology 2022 Jan;256(1):83-92
The Journal of pathology 2022 Jan;256(1):83-92
Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases.
Fu J, Zhou M, Gritsenko MA, Nakayasu ES, Song L, Luo ZQ
eLife 2022 Jan 27;11
eLife 2022 Jan 27;11
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.
Zheng Y, Deng J, Han L, Zhuang MW, Xu Y, Zhang J, Nan ML, Xiao Y, Zhan P, Liu X, Gao C, Wang PH
Signal transduction and targeted therapy 2022 Jan 24;7(1):22
Signal transduction and targeted therapy 2022 Jan 24;7(1):22
Golgi phosphoprotein 3 promotes angiogenesis and sorafenib resistance in hepatocellular carcinoma via upregulating exosomal miR-494-3p.
Gao Y, Yin Z, Qi Y, Peng H, Ma W, Wang R, Li W
Cancer cell international 2022 Jan 24;22(1):35
Cancer cell international 2022 Jan 24;22(1):35
Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via M2 macrophages.
Li K, Yan G, Huang H, Zheng M, Ma K, Cui X, Lu D, Zheng L, Zhu B, Cheng J, Zhao J
Journal of nanobiotechnology 2022 Jan 20;20(1):38
Journal of nanobiotechnology 2022 Jan 20;20(1):38
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Shi J, Li Z, Xu R, Zhang J, Zhou Q, Gao R, Lu H, Lan Y, Zhao K, He H, Gao F, He W
Journal of virology 2022 Jan 12;96(1):e0169521
Journal of virology 2022 Jan 12;96(1):e0169521
Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.
Bryant JD, Lei Y, VanPortfliet JJ, Winters AD, West AP
Current protocols 2022 Feb;2(2):e372
Current protocols 2022 Feb;2(2):e372
Splicing factor arginine/serine-rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome-based cellular communication.
Zhang Y, Yu X, Sun R, Min J, Tang X, Lin Z, Xie S, Li X, Lu S, Tian Z, Gu C, Teng L, Yang Y
Clinical and translational medicine 2022 Feb;12(2):e684
Clinical and translational medicine 2022 Feb;12(2):e684
Plasma extracellular vesicle microRNA profiling and the identification of a diagnostic signature for stage I lung adenocarcinoma.
Gao S, Guo W, Liu T, Liang N, Ma Q, Gao Y, Tan F, Xue Q, He J
Cancer science 2022 Feb;113(2):648-659
Cancer science 2022 Feb;113(2):648-659
Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.
Bian M, Fan R, Yang Z, Chen Y, Xu Z, Lu Y, Liu W
Journal of medicinal chemistry 2022 Feb 10;65(3):1848-1866
Journal of medicinal chemistry 2022 Feb 10;65(3):1848-1866
Atrophic skeletal muscle fibre-derived small extracellular vesicle miR-690 inhibits satellite cell differentiation during ageing.
Shao X, Gong W, Wang Q, Wang P, Shi T, Mahmut A, Qin J, Yao Y, Yan W, Chen D, Chen X, Jiang Q, Guo B
Journal of cachexia, sarcopenia and muscle 2022 Dec;13(6):3163-3180
Journal of cachexia, sarcopenia and muscle 2022 Dec;13(6):3163-3180
Circ-CREBBP inhibits sperm apoptosis via the PI3K-Akt signaling pathway by sponging miR-10384 and miR-143-3p.
Ding N, Zhang Y, Huang M, Liu J, Wang C, Zhang C, Cao J, Zhang Q, Jiang L
Communications biology 2022 Dec 7;5(1):1339
Communications biology 2022 Dec 7;5(1):1339
Identification of Circulating Exosomal microRNAs Associated with Radioiodine Refractory in Papillary Thyroid Carcinoma.
Li G, Chen W, Gong Y, Wei T, Gong R, Zhu J, Li Z, Lei J
Journal of personalized medicine 2022 Dec 7;12(12)
Journal of personalized medicine 2022 Dec 7;12(12)
Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.
Ding Y, Hu Q, Gan J, Zang X, Gu T, Wu Z, Cai G, Hong L
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Exosomes from the Uterine Cavity Mediate Immune Dysregulation via Inhibiting the JNK Signal Pathway in Endometriosis.
Jiang Y, Chai X, Chen S, Chen Z, Tian H, Liu M, Wu X
Biomedicines 2022 Dec 2;10(12)
Biomedicines 2022 Dec 2;10(12)
A cryostat-based frozen section method to increase the yield of extracellular vesicles extracted from different tissues.
Yang S, Qin W, Li X, Guo Q, Wang Y, Chen J, Li H, Zhang S, Min L
BioTechniques 2022 Aug;73(2):90-98
BioTechniques 2022 Aug;73(2):90-98
Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.
Ge X, He Z, Cao C, Xue T, Jing J, Ma R, Zhao W, Liu L, Jueraitetibaike K, Ma J, Feng Y, Qian Z, Zou Z, Chen L, Fu C, Song N, Yao B
Redox biology 2022 Aug;54:102380
Redox biology 2022 Aug;54:102380
Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency.
Wang F, Yang Y, Boudagh G, Eskelinen EL, Klionsky DJ, Malek SN
Autophagy 2022 Aug;18(8):1982-2000
Autophagy 2022 Aug;18(8):1982-2000
Differential proteomic analysis of plasma-derived exosomes as diagnostic biomarkers for chronic HBV-related liver disease.
Ye B, Shen Y, Chen H, Lin S, Mao W, Dong Y, Li X
Scientific reports 2022 Aug 24;12(1):14428
Scientific reports 2022 Aug 24;12(1):14428
Tumor-promoting mechanisms of macrophage-derived extracellular vesicles-enclosed microRNA-660 in breast cancer progression.
Li C, Li R, Hu X, Zhou G, Jiang G
Breast cancer research and treatment 2022 Apr;192(2):353-368
Breast cancer research and treatment 2022 Apr;192(2):353-368
Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway.
Liu W, Feng Y, Wang X, Ding J, Li H, Guan H, Chen Z
Bioengineered 2022 Apr;13(4):8850-8865
Bioengineered 2022 Apr;13(4):8850-8865
Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells.
Zhao Q, Chen H, Li X, Zeng B, Sun Z, Liu D, Chen Y, Zhang Y, Rosie Xing H, Wang J
Cell death discovery 2022 Apr 9;8(1):188
Cell death discovery 2022 Apr 9;8(1):188
miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia-reperfusion injury in steatotic grafts.
Wu L, Tian X, Zuo H, Zheng W, Li X, Yuan M, Tian X, Song H
Journal of nanobiotechnology 2022 Apr 22;20(1):196
Journal of nanobiotechnology 2022 Apr 22;20(1):196
VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion.
Dong X, Jiang D, Wang L, Zhao J, Yu L, Huang Y, Wu X, Zhu Y, Zhao Y, Zhao Q, Zhang G, Li X
iScience 2022 Apr 15;25(4):104042
iScience 2022 Apr 15;25(4):104042
Autophagy-Based Unconventional Secretory for AIM2 Inflammasome Drives DNA Damage Resistance During Intervertebral Disc Degeneration.
Li S, Liao Z, Luo R, Song Y, Wang K, Feng X, Ou Y, Wu X, Zhang Y, Gao Y, Yin H, Yang C
Frontiers in cell and developmental biology 2021;9:672847
Frontiers in cell and developmental biology 2021;9:672847
MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.
Yang W, Tu H, Tang K, Huang H, Ou S, Wu J
Frontiers in cardiovascular medicine 2021;8:709079
Frontiers in cardiovascular medicine 2021;8:709079
Identification of the Association Between Toll-Like Receptors and T-Cell Activation in Takayasu's Arteritis.
Tian Y, Huang B, Li J, Tian X, Zeng X
Frontiers in immunology 2021;12:792901
Frontiers in immunology 2021;12:792901
GATA4-driven miR-206-3p signatures control orofacial bone development by regulating osteogenic and osteoclastic activity.
Guo S, Gu J, Ma J, Xu R, Wu Q, Meng L, Liu H, Li L, Xu Y
Theranostics 2021;11(17):8379-8395
Theranostics 2021;11(17):8379-8395
LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.
Xiong J, Wu L, Huang L, Wu C, Liu Z, Deng W, Ma S, Zhou Z, Yu H, Cao K
Frontiers in oncology 2021;11:718876
Frontiers in oncology 2021;11:718876
SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.
Han L, Zhuang MW, Deng J, Zheng Y, Zhang J, Nan ML, Zhang XJ, Gao C, Wang PH
Journal of medical virology 2021 Sep;93(9):5376-5389
Journal of medical virology 2021 Sep;93(9):5376-5389
Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds.
Huang J, Yu M, Yin W, Liang B, Li A, Li J, Li X, Zhao S, Liu F
Bioactive materials 2021 Sep;6(9):2841-2853
Bioactive materials 2021 Sep;6(9):2841-2853
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Liu H, Chen B, Guo B, Deng X, Wang B, Dou X
Molecular neurobiology 2021 Sep;58(9):4251-4267
Molecular neurobiology 2021 Sep;58(9):4251-4267
Neuronal Exosomes Secreted under Oxygen-Glucose Deprivation/Reperfusion Presenting Differentially Expressed miRNAs and Affecting Neuronal Survival and Neurite Outgrowth.
Chiang CS, Fu SJ, Hsu CL, Jeng CJ, Tang CY, Huang YS, Tang SC
Neuromolecular medicine 2021 Sep;23(3):404-415
Neuromolecular medicine 2021 Sep;23(3):404-415
Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1.
Jia W, Zou X, Xu Z, Bai L, Shan A, Li Y, Shi J, Yang F, Ding C, Narimatsu H, Zhang Y
Glycobiology 2021 Sep 9;31(8):947-958
Glycobiology 2021 Sep 9;31(8):947-958
Differential Expression Pattern of Goat Uterine Fluids Extracellular Vesicles miRNAs during Peri-Implantation.
Xie Y, Liu G, Zang X, Hu Q, Zhou C, Li Y, Liu D, Hong L
Cells 2021 Sep 3;10(9)
Cells 2021 Sep 3;10(9)
Hemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence.
Zheng H, Liang X, Han Q, Shao Z, Zhang Y, Shi L, Hong Y, Li W, Mai C, Mo Q, Fu Q, Ma X, Lin F, Li M, Hu B, Li X, Zhang Y
Journal of nanobiotechnology 2021 Oct 21;19(1):332
Journal of nanobiotechnology 2021 Oct 21;19(1):332
Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.
Rimal S, Li Y, Vartak R, Geng J, Tantray I, Li S, Huh S, Vogel H, Glabe C, Grinberg LT, Spina S, Seeley WW, Guo S, Lu B
Acta neuropathologica communications 2021 Oct 18;9(1):169
Acta neuropathologica communications 2021 Oct 18;9(1):169
Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation.
Zhang X, Qu YY, Liu L, Qiao YN, Geng HR, Lin Y, Xu W, Cao J, Zhao JY
Cell reports 2021 Oct 12;37(2):109821
Cell reports 2021 Oct 12;37(2):109821
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Cheng L, Yu P, Li F, Jiang X, Jiao X, Shen Y, Lai X
Human cell 2021 Nov;34(6):1697-1708
Human cell 2021 Nov;34(6):1697-1708
Hypercholesterolemia risk associated Abca6 does not regulate lipoprotein metabolism in mice or hamster.
He B, Kang S, Chen Z, Liu X, Wang J, Li X, Liu X, Zheng L, Luo M, Wang Y
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 Nov;1866(11):159006
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 Nov;1866(11):159006
Comparison of MicroRNA Profiles in Extracellular Vesicles from Small and Large Goat Follicular Fluid.
Ding Q, Jin M, Kalds P, Meng C, Wang H, Zhong J, Wang X, Chen Y
Animals : an open access journal from MDPI 2021 Nov 8;11(11)
Animals : an open access journal from MDPI 2021 Nov 8;11(11)
hnRNPA2B1-Mediated Extracellular Vesicles Sorting of miR-122-5p Potentially Promotes Lung Cancer Progression.
Li C, Qin F, Wang W, Ni Y, Gao M, Guo M, Sun G
International journal of molecular sciences 2021 Nov 28;22(23)
International journal of molecular sciences 2021 Nov 28;22(23)
AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway.
Mak HY, Ouyang Q, Tumanov S, Xu J, Rong P, Dong F, Lam SM, Wang X, Lukmantara I, Du X, Gao M, Brown AJ, Gong X, Shui G, Stocker R, Huang X, Chen S, Yang H
Nature communications 2021 Nov 25;12(1):6877
Nature communications 2021 Nov 25;12(1):6877
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
Wang D, Ye Z, Wei W, Yu J, Huang L, Zhang H, Yue J
eLife 2021 Nov 19;10
eLife 2021 Nov 19;10
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Liu H, Liang J, Zhong Y, Xiao G, Efferth T, Georgiev MI, Vargas-De-La-Cruz C, Bajpai VK, Caprioli G, Liu J, Lin J, Wu H, Peng L, Li Y, Ma L, Xiao J, Wang Q
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
Long F, Yang D, Wang J, Wang Q, Ni T, Wei G, Zhu Y, Liu X
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins.
Chen F, Yan B, Ren J, Lyu R, Wu Y, Guo Y, Li D, Zhang H, Hu J
The Journal of cell biology 2021 May 3;220(5)
The Journal of cell biology 2021 May 3;220(5)
The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry.
Zhang J, Huang F, Xia B, Yuan Y, Yu F, Wang G, Chen Q, Wang Q, Li Y, Li R, Song Z, Pan T, Chen J, Lu G, Zhang H
Signal transduction and targeted therapy 2021 May 12;6(1):189
Signal transduction and targeted therapy 2021 May 12;6(1):189
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Shi M, Huang XY, Ren XY, Wei XY, Ma Y, Lin ZZ, Liu DT, Song L, Zhao TJ, Li G, Yao L, Zhu M, Zhang C, Xie C, Wu Y, Wu HM, Fan LP, Ou J, Zhan YH, Lin SY, Lin SC
Nature cell biology 2021 Mar;23(3):268-277
Nature cell biology 2021 Mar;23(3):268-277
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι.
Zhang Y, Chen Y, Li Y, Huang F, Luo B, Yuan Y, Xia B, Ma X, Yang T, Yu F, Liu J, Liu B, Song Z, Chen J, Yan S, Wu L, Pan T, Zhang X, Li R, Huang W, He X, Xiao F, Zhang J, Zhang H
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 8;118(23)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 8;118(23)
A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation.
Takahashi K, Niki T, Ogawa E, Fumika K, Nishioka Y, Sawa M, Arai H, Mukai K, Taguchi T
Scientific reports 2021 Jun 7;11(1):11996
Scientific reports 2021 Jun 7;11(1):11996
Identification of exosome miRNAs in bronchial epithelial cells after PM2.5 chronic exposure.
Wang Y, Zhong Y, Sun K, Fan Y, Liao J, Wang G
Ecotoxicology and environmental safety 2021 Jun 1;215:112127
Ecotoxicology and environmental safety 2021 Jun 1;215:112127
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
Chai P, Cheng Y, Hou C, Yin L, Zhang D, Hu Y, Chen Q, Zheng P, Teng J, Chen J
The Journal of cell biology 2021 Jul 5;220(7)
The Journal of cell biology 2021 Jul 5;220(7)
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Huang R, Hao C, Wang D, Zhao Q, Li C, Wang C, Yao W
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Secretome of Activated Fibroblasts Induced by Exosomes for the Discovery of Biomarkers in Non-Small Cell Lung Cancer.
Zhang J, Fu B, Li M, Mi S
Small (Weinheim an der Bergstrasse, Germany) 2021 Jan;17(4):e2004750
Small (Weinheim an der Bergstrasse, Germany) 2021 Jan;17(4):e2004750
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Yang J, Cao LL, Wang XP, Guo W, Guo RB, Sun YQ, Xue TF, Cai ZY, Ji J, Cheng H, Sun XL
Cell death & disease 2021 Jan 6;12(1):23
Cell death & disease 2021 Jan 6;12(1):23
Small RNA-seq analysis of extracellular vesicles from porcine uterine flushing fluids during peri-implantation.
Hua R, Wang Y, Lian W, Li W, Xi Y, Xue S, Kang T, Lei M
Gene 2021 Jan 15;766:145117
Gene 2021 Jan 15;766:145117
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
Xin D, Li T, Chu X, Ke H, Liu D, Wang Z
Pharmacological research 2021 Feb;164:105322
Pharmacological research 2021 Feb;164:105322
GBA Mutations Influence the Release and Pathological Effects of Small Extracellular Vesicles from Fibroblasts of Patients with Parkinson's Disease.
Cerri S, Ghezzi C, Ongari G, Croce S, Avenali M, Zangaglia R, Di Monte DA, Valente EM, Blandini F
International journal of molecular sciences 2021 Feb 23;22(4)
International journal of molecular sciences 2021 Feb 23;22(4)
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Wang X, Wang H, Xu B, Huang D, Nie C, Pu L, Zajac GJM, Yan H, Zhao J, Shi F, Emmer BT, Lu J, Wang R, Dong X, Dai J, Zhou W, Wang C, Gao G, Wang Y, Willer C, Lu X, Zhu Y, Chen XW
Cell metabolism 2021 Feb 2;33(2):350-366.e7
Cell metabolism 2021 Feb 2;33(2):350-366.e7
Thromboangiitis obliterans plasma-derived exosomal miR-223-5p inhibits cell viability and promotes cell apoptosis of human vascular smooth muscle cells by targeting VCAM1.
Deng Y, Tong J, Shi W, Tian Z, Yu B, Tang J
Annals of medicine 2021 Dec;53(1):1129-1141
Annals of medicine 2021 Dec;53(1):1129-1141
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Gao L, Nie X, Gou R, Hu Y, Dong H, Li X, Lin B
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Chen Y, Hu M, Deng F, Wang P, Lin J, Zheng Z, Liu Y, Dong L, Lu X, Chen Z, Zhou J, Zuo D
Cell calcium 2021 Dec;100:102477
Cell calcium 2021 Dec;100:102477
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.
Liu SJ, Meng MY, Han S, Gao H, Zhao YY, Yang Y, Lin ZY, Yang LR, Zhu K, Han R, Huang WW, Wang RQ, Yang LL, Wang WJ, Li L, Wang XD, Hou ZL, Liao LW, Yang L
Rejuvenation research 2021 Aug;24(4):283-293
Rejuvenation research 2021 Aug;24(4):283-293
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
Zhao Y, He L, Wang T, Zhu L, Yan N
Metabolites 2021 Aug 23;11(8)
Metabolites 2021 Aug 23;11(8)
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Du Y, Wang J, Xiong J, Fang N, Ji WK
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Japanese encephalitis virus manipulates lysosomes membrane for RNA replication and utilizes autophagy components for intracellular growth.
Xu Q, Huang L, Xing J, Zhang J, Li H, Liu L, Hu C, Liao M, Yue J, Qi W
Veterinary microbiology 2021 Apr;255:109025
Veterinary microbiology 2021 Apr;255:109025
Use of four genes in exosomes as biomarkers for the identification of lung adenocarcinoma and lung squamous cell carcinoma.
Cao B, Wang P, Gu L, Liu J
Oncology letters 2021 Apr;21(4):249
Oncology letters 2021 Apr;21(4):249
STING regulates BCR signaling in normal and malignant B cells.
Tang CA, Lee AC, Chang S, Xu Q, Shao A, Lo Y, Spalek WT, Pinilla-Ibarz JA, Del Valle JR, Hu CA
Cellular & molecular immunology 2021 Apr;18(4):1016-1031
Cellular & molecular immunology 2021 Apr;18(4):1016-1031
Adipose-derived stem cell exosomes facilitate rotator cuff repair by mediating tendon-derived stem cells.
Fu G, Lu L, Pan Z, Fan A, Yin F
Regenerative medicine 2021 Apr;16(4):359-372
Regenerative medicine 2021 Apr;16(4):359-372
Extracellular-vesicle containing miRNA-503-5p released by macrophages contributes to atherosclerosis.
Wang Y, Xu Z, Wang X, Zheng J, Peng L, Zhou Y, Song Y, Lu Z
Aging 2021 Apr 19;13(8):12239-12257
Aging 2021 Apr 19;13(8):12239-12257
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
Torres-Odio S, Lei Y, Gispert S, Maletzko A, Key J, Menissy SS, Wittig I, Auburger G, West AP
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage.
Tung SL, Fanelli G, Matthews RI, Bazoer J, Letizia M, Vizcay-Barrena G, Faruqu FN, Philippeos C, Hannen R, Al-Jamal KT, Lombardi G, Smyth LA
Frontiers in cell and developmental biology 2020;8:317
Frontiers in cell and developmental biology 2020;8:317
Mechanism of Sanguinarine in Inhibiting Macrophages to Promote Metastasis and Proliferation of Lung Cancer via Modulating the Exosomes in A549 Cells.
Yu Y, Luo Y, Fang Z, Teng W, Yu Y, Tian J, Guo P, Xu R, Wu J, Li Y
OncoTargets and therapy 2020;13:8989-9003
OncoTargets and therapy 2020;13:8989-9003
Enrichment of CD44 in Exosomes From Breast Cancer Cells Treated With Doxorubicin Promotes Chemoresistance.
Wang X, Cheng K, Zhang G, Jia Z, Yu Y, Guo J, Hua Y, Guo F, Li X, Zou W, Sun H, Dong J, Yang Z
Frontiers in oncology 2020;10:960
Frontiers in oncology 2020;10:960
Proteomic Profiling of Serum Exosomes From Patients With Metastatic Gastric Cancer.
Ding XQ, Wang ZY, Xia D, Wang RX, Pan XR, Tong JH
Frontiers in oncology 2020;10:1113
Frontiers in oncology 2020;10:1113
GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice.
Li X, Zhang Y, Zhang M, Wang Y
Scientific reports 2020 Sep 30;10(1):16168
Scientific reports 2020 Sep 30;10(1):16168
Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.
Xin D, Li T, Chu X, Ke H, Yu Z, Cao L, Bai X, Liu D, Wang Z
Acta biomaterialia 2020 Sep 1;113:597-613
Acta biomaterialia 2020 Sep 1;113:597-613
Insight into the proteomic profiling of exosomes secreted by human OM-MSCs reveals a new potential therapy.
Xun C, Ge L, Tang F, Wang L, Zhuo Y, Long L, Qi J, Hu L, Duan D, Chen P, Lu M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110584
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110584
Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging.
Yang D, Wang Q, Wei G, Wu J, Zhu YC, Zhu Q, Ni T, Liu X, Zhu YZ
Aging 2020 Nov 3;12(21):21423-21445
Aging 2020 Nov 3;12(21):21423-21445
Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.
Song L, Liu Z, Hu HH, Yang Y, Li TY, Lin ZZ, Ye J, Chen J, Huang X, Liu DT, Zhou J, Shi Y, Zhao H, Xie C, Chen L, Song E, Lin SY, Lin SC
Nature communications 2020 Nov 17;11(1):5842
Nature communications 2020 Nov 17;11(1):5842
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Li J, Liu X, Zang S, Zhou J, Zhang F, Sun B, Qi D, Li X, Kong J, Jin D, Yang X, Luo Y, Lu Y, Lin B, Niu W, Liu T
Cancer letters 2020 Nov 1;492:71-83
Cancer letters 2020 Nov 1;492:71-83
Oncoprotein SND1 hijacks nascent MHC-I heavy chain to ER-associated degradation, leading to impaired CD8(+) T cell response in tumor.
Wang Y, Wang X, Cui X, Zhuo Y, Li H, Ha C, Xin L, Ren Y, Zhang W, Sun X, Ge L, Liu X, He J, Zhang T, Zhang K, Yao Z, Yang X, Yang J
Science advances 2020 May;6(22)
Science advances 2020 May;6(22)
Exosomal long non-coding RNA MSTRG.292666.16 is associated with osimertinib (AZD9291) resistance in non-small cell lung cancer.
Deng Q, Fang Q, Xie B, Sun H, Bao Y, Zhou S
Aging 2020 May 6;12(9):8001-8015
Aging 2020 May 6;12(9):8001-8015
HPV + HNSCC-derived exosomal miR-9 induces macrophage M1 polarization and increases tumor radiosensitivity.
Tong F, Mao X, Zhang S, Xie H, Yan B, Wang B, Sun J, Wei L
Cancer letters 2020 May 28;478:34-44
Cancer letters 2020 May 28;478:34-44
Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.
Gao M, Dong Z, Sun J, Liu W, Xu M, Li C, Zhu P, Yang X, Shang X, Wu Y, Liu S
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113717
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113717
Characterization of serum small extracellular vesicles and their small RNA contents across humans, rats, and mice.
Zhao F, Cheng L, Shao Q, Chen Z, Lv X, Li J, He L, Sun Y, Ji Q, Lu P, Ji Y, Ji J
Scientific reports 2020 Mar 6;10(1):4197
Scientific reports 2020 Mar 6;10(1):4197
APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin.
Uzureau S, Lecordier L, Uzureau P, Hennig D, Graversen JH, Homblé F, Mfutu PE, Oliveira Arcolino F, Ramos AR, La Rovere RM, Luyten T, Vermeersch M, Tebabi P, Dieu M, Cuypers B, Deborggraeve S, Rabant M, Legendre C, Moestrup SK, Levtchenko E, Bultynck G, Erneux C, Pérez-Morga D, Pays E
Cell reports 2020 Mar 17;30(11):3821-3836.e13
Cell reports 2020 Mar 17;30(11):3821-3836.e13
Design of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling.
Xu L, Faruqu FN, Liam-Or R, Abu Abed O, Li D, Venner K, Errington RJ, Summers H, Wang JT, Al-Jamal KT
Journal of extracellular vesicles 2020 Jun 19;9(1):1779458
Journal of extracellular vesicles 2020 Jun 19;9(1):1779458
The protective effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on cisplatin-damaged granulosa cells.
Zhang J, Yin H, Jiang H, Du X, Yang Z
Taiwanese journal of obstetrics & gynecology 2020 Jul;59(4):527-533
Taiwanese journal of obstetrics & gynecology 2020 Jul;59(4):527-533
Three-dimensional culture of dental pulp pluripotent-like stem cells (DPPSCs) enhances Nanog expression and provides a serum-free condition for exosome isolation.
Faruqu FN, Zhou S, Sami N, Gheidari F, Lu H, Al-Jamal KT
FASEB bioAdvances 2020 Jul;2(7):419-433
FASEB bioAdvances 2020 Jul;2(7):419-433
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Duan TL, Jiao H, He GJ, Yan YB
Cells 2020 Jan 9;9(1)
Cells 2020 Jan 9;9(1)
Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.
Li M, Wang J, Fu L, Lu Y, Xu J, Zhou L, Zhu H, Fang L, Feng Z, Xie T, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 15;26:e920376
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 15;26:e920376
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Li N, Luo X, Yu Q, Yang P, Chen Z, Wang X, Jiang J, Xu J, Gong Q, Eizirik DL, Zhou Z, Zhao J, Xiong F, Zhang S, Wang CY
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.
Zheng Y, Zhuang MW, Han L, Zhang J, Nan ML, Zhan P, Kang D, Liu X, Gao C, Wang PH
Signal transduction and targeted therapy 2020 Dec 28;5(1):299
Signal transduction and targeted therapy 2020 Dec 28;5(1):299
Polyethylene Glycol 35 (PEG35) Modulates Exosomal Uptake and Function.
Ferrero-Andrés A, Closa D, Roselló-Catafau J, Folch-Puy E
Polymers 2020 Dec 18;12(12)
Polymers 2020 Dec 18;12(12)
Mycobacterium tuberculosis MmsA (Rv0753c) Interacts with STING and Blunts the Type I Interferon Response.
Sun Y, Zhang W, Dong C, Xiong S
mBio 2020 Dec 1;11(6)
mBio 2020 Dec 1;11(6)
SCYL1 arginine methylation by PRMT1 is essential for neurite outgrowth via Golgi morphogenesis.
Amano G, Matsuzaki S, Mori Y, Miyoshi K, Han S, Shikada S, Takamura H, Yoshimura T, Katayama T
Molecular biology of the cell 2020 Aug 15;31(18):1963-1973
Molecular biology of the cell 2020 Aug 15;31(18):1963-1973
USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy.
Niu K, Fang H, Chen Z, Zhu Y, Tan Q, Wei D, Li Y, Balajee AS, Zhao Y
Autophagy 2020 Apr;16(4):724-734
Autophagy 2020 Apr;16(4):724-734
Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress.
Zheng D, Chen Y, Ai S, Zhang R, Gao Z, Liang C, Cao L, Chen Y, Hong Z, Shi Y, Wang L, Li X, Yang Z
Research (Washington, D.C.) 2019;2019:4803624
Research (Washington, D.C.) 2019;2019:4803624
Identification of Lipid Droplet Proteomes by Proximity Labeling Proteomics Using APEX2.
Bersuker K, Olzmann JA
Methods in molecular biology (Clifton, N.J.) 2019;2008:57-72
Methods in molecular biology (Clifton, N.J.) 2019;2008:57-72
Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation.
Yan H, Gao Y, Ding Q, Liu J, Li Y, Jin M, Xu H, Ma S, Wang X, Zeng W, Chen Y
International journal of biological sciences 2019;15(7):1368-1382
International journal of biological sciences 2019;15(7):1368-1382
Proteomic analysis of seminal extracellular vesicle proteins involved in asthenozoospermia by iTRAQ.
Lin Y, Liang A, He Y, Li Z, Li Z, Wang G, Sun F
Molecular reproduction and development 2019 Sep;86(9):1094-1105
Molecular reproduction and development 2019 Sep;86(9):1094-1105
Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress.
Merriman C, Fu D
The Journal of biological chemistry 2019 Nov 8;294(45):16992-17006
The Journal of biological chemistry 2019 Nov 8;294(45):16992-17006
Protective effect of Barbaloin in a rat model of myocardial ischemia reperfusion injury through the regulation of the CNPY2‑PERK pathway.
Cui Y, Wang Y, Liu G
International journal of molecular medicine 2019 May;43(5):2015-2023
International journal of molecular medicine 2019 May;43(5):2015-2023
Peri-Infarct Upregulation of the Oxytocin Receptor in Vascular Dementia.
McKay EC, Beck JS, Khoo SK, Dykema KJ, Cottingham SL, Winn ME, Paulson HL, Lieberman AP, Counts SE
Journal of neuropathology and experimental neurology 2019 May 1;78(5):436-452
Journal of neuropathology and experimental neurology 2019 May 1;78(5):436-452
Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection.
Wang J, Teng Y, Zhao G, Li F, Hou A, Sun B, Kong W, Gao F, Cai L, Jiang C
International journal of molecular sciences 2019 Mar 27;20(7)
International journal of molecular sciences 2019 Mar 27;20(7)
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
Du Y, Hu H, Pei X, Du K, Wei T
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
Two novel ANK1 loss-of-function mutations in Chinese families with hereditary spherocytosis.
Hao L, Li S, Ma D, Chen S, Zhang B, Xiao D, Zhang J, Jiang N, Jiang S, Ma J
Journal of cellular and molecular medicine 2019 Jun;23(6):4454-4463
Journal of cellular and molecular medicine 2019 Jun;23(6):4454-4463
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
An H, Ordureau A, Paulo JA, Shoemaker CJ, Denic V, Harper JW
Molecular cell 2019 Jun 6;74(5):891-908.e10
Molecular cell 2019 Jun 6;74(5):891-908.e10
Zika Virus Subverts Stress Granules To Promote and Restrict Viral Gene Expression.
Bonenfant G, Williams N, Netzband R, Schwarz MC, Evans MJ, Pager CT
Journal of virology 2019 Jun 15;93(12)
Journal of virology 2019 Jun 15;93(12)
Microglia as modulators of exosomal alpha-synuclein transmission.
Xia Y, Zhang G, Han C, Ma K, Guo X, Wan F, Kou L, Yin S, Liu L, Huang J, Xiong N, Wang T
Cell death & disease 2019 Feb 20;10(3):174
Cell death & disease 2019 Feb 20;10(3):174
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Shi J, Hu X, Guo Y, Wang L, Ji J, Li J, Zhang ZR
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway.
Wang S, Su X, Xu M, Xiao X, Li X, Li H, Keating A, Zhao RC
Stem cell research & therapy 2019 Apr 11;10(1):117
Stem cell research & therapy 2019 Apr 11;10(1):117
Adipocyte-Derived Exosomes Carrying Sonic Hedgehog Mediate M1 Macrophage Polarization-Induced Insulin Resistance via Ptch and PI3K Pathways.
Song M, Han L, Chen FF, Wang D, Wang F, Zhang L, Wang ZH, Zhong M, Tang MX, Zhang W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(4):1416-1432
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(4):1416-1432
Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling.
Li M, Du W, Zhou M, Zheng L, Song E, Hou J
Biophysics reports 2018;4(6):329-338
Biophysics reports 2018;4(6):329-338
Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway.
Zhou X, Yan T, Huang C, Xu Z, Wang L, Jiang E, Wang H, Chen Y, Liu K, Shao Z, Shang Z
Journal of experimental & clinical cancer research : CR 2018 Oct 3;37(1):242
Journal of experimental & clinical cancer research : CR 2018 Oct 3;37(1):242
In Vivo Tracking of Multiple Tumor Exosomes Labeled by Phospholipid-Based Bioorthogonal Conjugation.
Zhang P, Dong B, Zeng E, Wang F, Jiang Y, Li D, Liu D
Analytical chemistry 2018 Oct 2;90(19):11273-11279
Analytical chemistry 2018 Oct 2;90(19):11273-11279
Enhanced MiR-711 transcription by PPARγ induces endoplasmic reticulum stress-mediated apoptosis targeting calnexin in rat cardiomyocytes after myocardial infarction.
Zhao N, Mi L, Zhang X, Xu M, Yu H, Liu Z, Liu X, Guan G, Gao W, Wang J
Journal of molecular and cellular cardiology 2018 May;118:36-45
Journal of molecular and cellular cardiology 2018 May;118:36-45
Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.
Li TY, Song L, Sun Y, Li J, Yi C, Lam SM, Xu D, Zhou L, Li X, Yang Y, Zhang CS, Xie C, Huang X, Shui G, Lin SY, Reue K, Lin SC
Nature communications 2018 May 15;9(1):1916
Nature communications 2018 May 15;9(1):1916
Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.
Xin X, Wang H, Han L, Wang M, Fang H, Hao Y, Li J, Zhang H, Zheng C, Shen C
Journal of virology 2018 May 1;92(9)
Journal of virology 2018 May 1;92(9)
A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.
Huang EY, To M, Tran E, Dionisio LTA, Cho HJ, Baney KLM, Pataki CI, Olzmann JA
Molecular biology of the cell 2018 May 1;29(9):1021-1030
Molecular biology of the cell 2018 May 1;29(9):1021-1030
A RAB27A 5' untranslated region structural variant associated with late-onset hemophagocytic lymphohistiocytosis and normal pigmentation.
Tesi B, Rascon J, Chiang SCC, Burnyte B, Löfstedt A, Fasth A, Heizmann M, Juozapaite S, Kiudeliene R, Kvedaraite E, Miseviciene V, Muleviciene A, Müller ML, Nordenskjöld M, Matuzeviciene R, Samaitiene R, Speckmann C, Stankeviciene S, Zekas V, Voss M, Ehl S, Vaiciene-Magistris N, Henter JI, Meeths M, Bryceson YT
The Journal of allergy and clinical immunology 2018 Jul;142(1):317-321.e8
The Journal of allergy and clinical immunology 2018 Jul;142(1):317-321.e8
The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.
Ganji R, Mukkavalli S, Somanji F, Raman M
Molecular and cellular biology 2018 Jul 1;38(13)
Molecular and cellular biology 2018 Jul 1;38(13)
A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.
Bersuker K, Peterson CWH, To M, Sahl SJ, Savikhin V, Grossman EA, Nomura DK, Olzmann JA
Developmental cell 2018 Jan 8;44(1):97-112.e7
Developmental cell 2018 Jan 8;44(1):97-112.e7
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Luo H, Jiang M, Lian G, Liu Q, Shi M, Li TY, Song L, Ye J, He Y, Yao L, Zhang C, Lin ZZ, Zhang CS, Zhao TJ, Jia WP, Li P, Lin SY, Lin SC
Cell metabolism 2018 Apr 3;27(4):843-853.e6
Cell metabolism 2018 Apr 3;27(4):843-853.e6
Protein kinase D at the Golgi controls NLRP3 inflammasome activation.
Zhang Z, Meszaros G, He WT, Xu Y, de Fatima Magliarelli H, Mailly L, Mihlan M, Liu Y, Puig Gámez M, Goginashvili A, Pasquier A, Bielska O, Neven B, Quartier P, Aebersold R, Baumert TF, Georgel P, Han J, Ricci R
The Journal of experimental medicine 2017 Sep 4;214(9):2671-2693
The Journal of experimental medicine 2017 Sep 4;214(9):2671-2693
Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis.
Komaki M, Numata Y, Morioka C, Honda I, Tooi M, Yokoyama N, Ayame H, Iwasaki K, Taki A, Oshima N, Morita I
Stem cell research & therapy 2017 Oct 3;8(1):219
Stem cell research & therapy 2017 Oct 3;8(1):219
Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.
Liu Z, Wang Y, Wang Y, Dong W, Xia X, Song E, Song Y
Chemical research in toxicology 2017 Oct 16;30(10):1804-1814
Chemical research in toxicology 2017 Oct 16;30(10):1804-1814
Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion.
Li P, Du J, Goodier JL, Hou J, Kang J, Kazazian HH Jr, Zhao K, Yu XF
Nucleic acids research 2017 May 5;45(8):4619-4631
Nucleic acids research 2017 May 5;45(8):4619-4631
REG3β modifies cell tumor function by impairing extracellular vesicle uptake.
Bonjoch L, Gironella M, Iovanna JL, Closa D
Scientific reports 2017 Jun 9;7(1):3143
Scientific reports 2017 Jun 9;7(1):3143
Dominant ER Stress-Inducing WFS1 Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts.
De Franco E, Flanagan SE, Yagi T, Abreu D, Mahadevan J, Johnson MB, Jones G, Acosta F, Mulaudzi M, Lek N, Oh V, Petz O, Caswell R, Ellard S, Urano F, Hattersley AT
Diabetes 2017 Jul;66(7):2044-2053
Diabetes 2017 Jul;66(7):2044-2053
DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.
Ding J, Shao L, Yao Y, Tong X, Liu H, Yue S, Xie L, Cheng SY
Scientific reports 2017 Jul 13;7(1):5296
Scientific reports 2017 Jul 13;7(1):5296
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.
Sasai M, Sakaguchi N, Ma JS, Nakamura S, Kawabata T, Bando H, Lee Y, Saitoh T, Akira S, Iwasaki A, Standley DM, Yoshimori T, Yamamoto M
Nature immunology 2017 Aug;18(8):899-910
Nature immunology 2017 Aug;18(8):899-910
Involvement of exosomes in lung inflammation associated with experimental acute pancreatitis.
Bonjoch L, Casas V, Carrascal M, Closa D
The Journal of pathology 2016 Oct;240(2):235-45
The Journal of pathology 2016 Oct;240(2):235-45
Quantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells.
Zhou Y, Xiong L, Zhang Y, Yu R, Jiang X, Xu G
Journal of proteomics 2016 Oct 4;148:94-104
Journal of proteomics 2016 Oct 4;148:94-104
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
Lin JJ, Wang RY, Chen JC, Chiu CC, Liao MH, Wu YJ
International journal of molecular sciences 2016 Oct 27;17(11)
International journal of molecular sciences 2016 Oct 27;17(11)
Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector.
Dong N, Niu M, Hu L, Yao Q, Zhou R, Shao F
Nature microbiology 2016 Dec 12;2:16236
Nature microbiology 2016 Dec 12;2:16236
Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancer.
Wang X, Xu C, Hua Y, Sun L, Cheng K, Jia Z, Han Y, Dong J, Cui Y, Yang Z
Journal of experimental & clinical cancer research : CR 2016 Dec 1;35(1):186
Journal of experimental & clinical cancer research : CR 2016 Dec 1;35(1):186
Development of a mitochondria-based centrifugal ultrafiltration/liquid chromatography/mass spectrometry method for screening mitochondria-targeted bioactive constituents from complex matrixes: Herbal medicines as a case study.
Yang XX, Xu F, Wang D, Yang ZW, Tan HR, Shang MY, Wang X, Cai SQ
Journal of chromatography. A 2015 Sep 25;1413:33-46
Journal of chromatography. A 2015 Sep 25;1413:33-46
Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.
Jokinen R, Lahtinen T, Marttinen P, Myöhänen M, Ruotsalainen P, Yeung N, Shvetsova A, Kastaniotis AJ, Hiltunen JK, Öhman T, Nyman TA, Weiler H, Battersby BJ
Genetics 2015 May;200(1):221-35
Genetics 2015 May;200(1):221-35
IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection.
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 10427-2-AP(CANX antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of A431 cells, using CANX antibody 10427-2-AP at 1:50 dilution and FITC-labeled donkey anti-rabbit IgG(green).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10427-2-AP(CANX antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10427-2-AP(CANX antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Calnexin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Calnexin. This antibody recognizes human,mouse,rat antigen. The Calnexin antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.
