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- Antibody Data
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- Product number
- 10904-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10904-1-AP, RRID:AB_2224377
- Product name
- IBA1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IBA1 antibody (Cat. #10904-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Therapeutic relevance of an EU-GMP certified Cannabis sativa L. strain in a dual in vivo model of cognitive impairment and chronic neuropathic pain.
Rosuvastatin attenuates blood-brain barrier dysfunction after ICH through modulation of CXCL12-associated VEGFR2/p38 MAPK signaling.
Stem Cell-Derived Exosomes Improve Neurological Dysfunction in a Rat Model of Moderate-to-Severe Cerebral Palsy.
Flavonoids of Ziziphora clinopodioides improve Alzheimer's cognitive impairment and inhibit NLRP3 inflammasome activation via autophagy-lysosome pathway.
Glaucine suppresses IL-16/CD4 to alleviate neuropathic pain via spinal p56(lck)-NMDA receptor signaling.
Thymic stromal lymphopoietin modification gates chronic pain via regulation of transient receptor potential vanilloid type 1-caspase1.
PROTAC-Mediated Degradation of mHTT Aggregates Attenuates Neurotoxicity in Cellular and R6/2 Mouse Models of Huntington's Disease.
Integrated stress response inhibition rescues inflammation-associated accelerated forgetting of recognition memory in mice.
Sphingosine-1-Phosphate Receptor 3 Mediated Neuroinflammation is Critically Involved in the Development of Brain Injury Following Cardiac Arrest in Mice.
Modulating GRP75 to restore calcium homeostasis: a novel neuroprotective strategy of CRSE6(#) in Parkinson's disease models.
A Ratiometric Afterglow Luminescence Probe for in Vivo Imaging of Neuroinflammation in Traumatic Brain Injury.
Blood-brain barrier-penetrative lipid nanoparticles enable systemic delivery of TRIM11 mRNA to disaggregate Tau in Alzheimer's disease models.
Tanshinone IIA-pretreated mesenchymal stem cells alleviate neuroinflammation in 3×Tg-AD mice via the TREM2/PI3K/Akt pathway.
Evodiamine alleviates MPTP-induced Parkinson's disease in mice by regulating gut microbiota and suppressing TLR4/MyD88/NF-kB pathway.
The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease.
M2 macrophage-derived exosomes delivering haptoglobin and interleukin-10 plasmids for synergistic therapy of intracerebral hemorrhage.
Triamcinolone acetonide nanoparticles ameliorate interstitial cystitis and anxiety/depression by targeting the bladder-metabolic-brain axis.
Electroacupuncture as a promising therapeutic strategy for chronic constriction injury-induced neuropathic pain: Insights into the PPARα/SIRT1/NF-κB axis.
Dynamic expression of type III collagen in the lesion core of post-ischemic brain colocalizing with angiogenesis and lipid droplets during fibrotic scar formation.
Japanese encephalitis virus activates the NLRP3/caspase-1/GSDMD signaling pathway in dopaminergic neurons.
Chronic Stress Leads to Time-Dependent Bone Loss Through HPA Axis Dysregulation and GR Nuclear Translocation Disorder.
Sodium tanshinone IIA sulfonate alleviates neuroinflammation-induced damage to hippocampal neurons by activating SIRT1 in mice with sepsis-associated encephalopathy.
Glycyrrhizic acid-loaded biomimetic hybrid liposomes targeting inflammatory cascades and PD-1/PD-L1 pathway to reverse neuroinflammation-driven cognitive decline.
Reducing Neuroinflammation via Inhibition of Fibrinogen Deposition and Microglial Activation as an Underlying Mechanism of Paning I Decoction in Ameliorating Parkinson's Disease Symptoms.
Nighttime-restricted feeding disrupts spermatogenesis in mice via gut microbiota-derived KYNA homeostasis.
Roflumilast Elicits Therapeutic and Neuroprotective Effects in 3-Nitropropionic Acid-Induced Huntington's Disease-Like Neurodegeneration in Rats by Mitigating NLRP3 Inflammasome-Mediated Pyroptosis, Ferroptosis, and Glial Activation.
Machine learning-guided Huanglian Jiedu decoction targets STING in periodontitis-induced Alzheimer's Disease.
High-intensity interval training remodels perineuronal nets in the medial prefrontal cortex to drive microglial polarization and alleviate osteoarthritis pain.
NIR-II-Responsive Biomimetic Nanoplatform for Precise Inhibition of Ischemic Stroke via Dual Modulation of Ion Channels and Microglia.
Luteolin-Loaded TGN/RAP12 Dual-Peptide Functionalized Nanoparticles: Synergistic Enhancement of BBB Penetration and Microglia Targeting in Alzheimer's Disease.
Neuro-bone-skin tri-regeneration via a microenvironment-responsive PRP-loaded chitosan hydrogel for traumatic brain injury therapy.
Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.
Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury.
RUVBL2 Regulates Microglia Metabolic Reprogramming to Mediate Stress Granules Aggregation Exacerbating Postoperative Delirium in Aged Mild Cognitive Impairment Rats.
IMR-1 ameliorates perinatal LPS-induced brain injury by promoting the conversion of glial cells into neurons.
Auditory activity sustains adult neurogenesis and cognition through the locus coeruleus-norepinephrine system.
Propionate Aggravates Anxiety and Cognitive Dysfunction in High-Fat Diet Mice by Activating Hippocampal Microglia-Mediated Neuroinflammation.
Platelet factors 4 produces an antidepressant effect in mice via inhibition of neuroinflammation.
Spermidine Attenuates Neuroimmune Dysfunction in Gulf War Illness via Modulation of the Gut- Brain Axis.
Thalamic glutamatergic neurons regulate seizure onset and generalization in temporal lobe epilepsy.
Naltrexone treatment improves anxiety- and depression-like behavior in alcohol-exposed mice.
Lipofuscin autofluorescence confounds intracellular amyloid β detection in the aged mouse brain.
Glutathione metabolism as a key regulator of oxidative hippocampal injury in sepsis-associated encephalopathy: an integrated proteomics and metabolomics study.
Coixol ameliorates dopaminergic neurodegeneration by inhibiting neuroinflammation and protecting mitochondrial function.
The protective effect of Blautia coccoides in secondary injury of intracerebral hemorrhage.
Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.
Effect of Fangxia-Dihuang Decoction on doxorubicin-induced cognitive impairment in breast cancer animal model.
Madecassoside exerts anti-neurodegeneration effects in protein l-isoaspartyl methyltransferase deficient mice via targeting PRDX2-mediated oxidative stress and inflammation.
Refinement of TSLP expression mediates chronic allodynia associated with IL22/STAT3 axis.
Thiamet-G ameliorates Parkinson's disease-associated cognitive impairment via increasing O-GlcNAcylation of STING in the microglia.
Huangqi Guizhi Wuwu decoction alleviate Oxaliplatin-Induced Peripheral Neuropathy by adjusting the myelin regeneration.
Nicotinamide Riboside Alleviates the Neurotoxic Injury of Dendritic Spine Plasticity Mediated by Hypoxic Microglial Activation.
Aging-related decline in the liver and brain is accelerated by refined diet consumption.
Human brain cell types shape host-rabies virus transcriptional interactions revealing a preexisting pro-viral astrocyte subpopulation.
Dectin-1 Drives Diabetic Retinopathy via Inducing Microglia-Mediated Inflammation and Blood-Retinal Barrier Breakdown.
Microglia in the Rostral Ventromedial Medulla Mediate Synaptic Pruning via the C1q/C3-CR3 Signaling Pathway-A Mechanism for the Chronic Orofacial Pain.
Deletion of ZNRF2 Exacerbates MPTP-Induced Parkinson's Disease by Activating mTOR-Mediated Neuroinflammatory Pathways.
Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway.
Modeling Alzheimer's Disease with APOE4 Neuron-Glial Brain Assembloids Reveals IGFBPs as Therapeutic Targets.
Ramelteon Ameliorates Isoflurane-Induced Hyperactivity and Social-Recognition Impairment in Aged Mice.
TDP-43 mediated oxidative stress induced mitochondrial dysfunction in neurons and hyperalgesia in sciatic nerve injured mice.
Disulfide-Appended siRNA Nanoeyedrops: Noninvasive Gene Therapy for Targeting Retinal Angiogenesis.
CircFGFR2 induces astrocyte pyroptosis to promote ischemic stroke.
Neuronutritional enhancement of antioxidant defense system through Nrf2/HO1/NQO1 axis in fibromyalgia.
Microglial activation drives neuronal dysregulation in alcohol-induced seizure susceptibility.
Kaempferol attenuated LPS-induced microglial neurotoxicity by promoting mitophagy to inhibit mtDNA-mediated NLRP3 inflammasome activation.
Urolithin B promotes the functional recovery of spinal cord injury by alleviating neuroinflammation via the inhibition of NLRP3 signaling pathway.
Trofinetide Improves Cognitive Function in APP/PS1 Mice by Suppressing Inflammation and Apoptosis.
Xiaoyao San against depression via glia-mediated neuroinflammation using network pharmacology and experimental validation.
Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.
GIV/Girdin Modulation of Microglial Activation in Ischemic Stroke: Impact of FTO-Mediated m6A Modification.
Berbamine alleviates neuropathic pain via suppressing spinal TMEM34/SGK1/FOXO3 axis.
Mg(2+)-Loaded Black Phosphorus Nanosheet Protects against Cerebral Ischemic Injury through Anti-Oxidative and Anti-Inflammatory Effects.
Ectoparasites enhance survival by suppressing host exploration and limiting dispersal.
Neutrophil Extracellular Traps Promote AIM2-Dependent Microglial Pyroptosis Following Stroke.
Clonidine Ameliorates Neuroinflammation in the Rat Model of Tourette Syndrome.
DANCR knockdown alleviates neuroinflammation and functional recovery after spinal cord injury via regulating the ACTN4 / STAT3 axis.
Exploring the active components and potential mechanisms of Zhimu-Huangbai herb-pair in the treatment of depression.
Inhibiting HMGB1/AGER/NF-κB pathway prevents pro-inflammatory microglia polarization and protect photoreceptors in retinitis pigmentosa.
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Transcranial magneto-acoustic stimulation enhances motor function and modulates cortical excitability of motor cortex in a Parkinson's disease mouse model.
Sinomenine alleviates neuroinflammation in chronic cerebral hypoperfusion by promoting M2 microglial polarization and inhibiting neuronal pyroptosis via exosomal miRNA-223-3p.
Multiple synergistic anti-aging effects of vascular cell adhesion molecule 1 functionalized nanoplatform to improve age-related neurodegenerative diseases.
Nanoemulsion-based pseudopolyrotaxane hydrogel for enhanced corneal bioavailability and treatment of corneal inflammation.
Allograft inflammatory Factor-1 induces the dedifferentiation of Vascular Smooth Muscle cells into a macrophage-like phenotype both in vivo and in vitro.
Electromagnetic pulse exposure induces neuroinflammation and blood-brain barrier disruption by activating the NLRP3 inflammasome/NF-κB signaling pathway in mice.
Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model.
Juvenile fluoxetine treatment affects the maturation of the medial prefrontal cortex and behavior of adolescent female rats.
Myelination Trajectory and Microglial Dynamics Following Repeated Sevoflurane Exposure in Developing Brain.
Chaperone-mediated autophagy, heat shock protein 70, and serotonin: novel targets of beta-hydroxybutyrate in HFFD/LPS-induced sporadic Alzheimer's disease model.
Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4.
Allopregnanolone relieves paclitaxel induced mechanical hypersensitivity via inhibiting spinal cord PGE(2)-EP2 mediated microglia-neuron signaling.
CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1-Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis.
Dragon's Blood Modulates Disulfidptosis-Related Genes to Alleviate Ischemic Brain Injury in Mice.
miR-210 Regulates Autophagy Through the AMPK/mTOR Signaling Pathway, Reduces Neuronal Cell Death and Inflammatory Responses, and Enhances Functional Recovery Following Cerebral Hemorrhage in Mice.
Visualization of P2X7 Receptors in Living Human Gliomas: An 18F-GSK1482160 PET Imaging and Neuropathology Study.
Qinglongyi nanoparticles alleviate neuroinflammation and promote neuronal survival by inhibiting neuronal ferroptosis in intracerebral hemorrhage.
miR-29a nanoparticles improve chronic insomnia by regulating microglia activation and hippocampal neuronal cell pyroptosis through PER2/NF-κB axis.
Senolytic Treatment Attenuates Global Ischemic Brain Injury and Enhances Cognitive Recovery by Targeting Mitochondria.
Targeting glial fibrillary acidic protein in glaucoma: a monoclonal antibody approach to modulate glial reactivity and neuroinflammation for neuroprotection.
GLUT1 maintains esophageal cancer stem cell-like characteristics by inhibiting autophagy-dependent ferroptosis via EGFR.
Anticonvulsant effect of Stachydrine on pentylenetetrazole-induced kindling seizure mouse model via Notch and NMDAR signaling pathways.
Human brain cell types shape host-rabies virus transcriptional interactions revealing a preexisting pro-viral astrocyte subpopulation.
Mesenchymal Stem Cell-Derived Mitochondrial Transfer Promotes Tip Cell Phenotype via Glutathione Metabolic Reprogramming in Stroke Mice.
Cyclophilin D knockdown/knockout promotes microglia M2 polarization by inhibiting STAT1 to alleviate neuroinflammation in neonatal white matter injury.
Targeting PD-L1 for Ischemic Stroke Recovery: Age-Dependent Modulation of Immune and BBB Pathways.
Incorporation of graphene oxide into collagenous biomaterials attenuates scar-forming phenotype transition of reactive astrocytes in vitro.
Developmental wave of programmed ganglion cell death in human retinal organoids.
Candesartan Mitigates Perioperative Neurocognitive Disorders by Modulating Hypertension-Linked Neuroinflammatory Factor.
The expression profile of type 1 equilibrative nucleoside transporter in aged C57BL/6J mouse brain.
Cannabidiol ameliorates seizures and neuronal damage in ferric chloride-induced posttraumatic epilepsy by targeting TRPV1 channel.
Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model.
Mild subcortical stroke induces widespread astrogliosis independent of microglia and age.
Botulinum toxin type A inhibits microglia pyroptosis by suppressing Cblb-mediated degradation of Pdlim1 to attenuate neuropathic pain.
Kaempferol ameliorated central nervous injury induced by alcohol uptake through improving intestinal barrier function.
Effects of ATF2/TSC1 on epilepsy by modulating the microphages polarization of microglia.
Poldip2 Aggravates inflammation in diabetic retinopathy by impairing mitophagy via the AMPK/ULK1/Pink1 pathway.
Integrative analysis identifies IL-6/JUN/MMP-9 pathway destroyed blood-brain-barrier in autism mice via machine learning and bioinformatic analysis.
Targeting modulation of the choroid plexus blood-CSF barrier and CSF hypersecretion via lipid nanoparticle-mediated co-delivery of siRNA and resveratrol.
SETD1B promotes brain cell ferroptosis in ischemic stroke mice via increasing H3K4me3 enrichment on the Tfrc promoter.
THSG counteracts microglial glycolytic reprogramming and neuronal necroptosis both in vivo and in vitro under conditions of neuroinflammation.
Magnolol acts as a neurorestorative agent in an A(β1‑42)‑induced mouse model of Alzheimer's disease.
Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage.
Remifentanil-induced inflammation in microglial cells: Activation of the PAK4-mediated NF-κB/NLRP3 pathway and onset of hyperalgesia.
Maternal separation during lactation affects recognition memory, emotional behaviors, hippocampus and gut microbiota composition in C57BL6J adolescent female mice.
The aqueous extract of Armadillidium vulgare Latreille alleviates neuropathic pain via inhibiting neuron-astrocyte crosstalk mediated by the IL-12-IFN-γ-IFNGR-CXCL10 pathway.
Taxus chinensis (Pilg.) Rehder fruit attenuates aging behaviors and neuroinflammation by inhibiting microglia activation via TLR4/NF-κB/NLRP3 pathway.
STEAP3-SLC39A8-mediated microglia ferroptosis involved in neurotoxicity in rats after exposure to lead and cadmium combined.
Altered ATP13A2/PARK9 Levels Influence α-Synuclein Accumulation in Neurons via Phagocytosis and Secretion in Glial Cells.
Semen Strychni Pulveratum and vomicine alleviate neuroinflammation in amyotrophic lateral sclerosis through cGAS-STING-TBK1 pathway.
Microglial activation and hypothalamic structural plasticity in HFD obesity: insights from semaglutide and minocycline.
Evaluation of TRPM2 Channel-Mediated Autophagic Signaling Pathway in Hippocampus and Cortex Tissues of Rat Offspring Following Prenatal Exposure to Elevated Alcohol Levels.
Microglia-derived Galectin-9 drives amyloid-β pathology in Alzheimer's disease.
Inhibition of Kv1.1 channels ameliorates Cu(II)-induced microglial activation and cognitive impairment in mice.
Demyelination of the amygdala mediates psychological stress-induced emotional disorders partially contributed by activation of P2X7R/NLRP3 cascade.
OTUD5 Protects Dopaminergic Neurons by Promoting the Degradation of α-Synuclein in Parkinson's Disease Model.
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.
Identification and Therapeutic Potential of Polymethoxylated Flavones in Citri Reticulatae Pericarpium for Alzheimer's Disease: Targeting Neuroinflammation.
Schisandra chinensis lignans exerts endocannabinoids-like antidepressive effect: The phagocytotic relationship of activated CB2R-mediated M2 microglia and "stressed-but-viable" neuron.
Baicalein alleviates long-term cognitive impairments induced by repeated neonatal sevoflurane exposure via inhibition of cortical microglial TLR4/NF-kB signaling.
Integrative single-cell and spatial transcriptome analysis reveals the functions of TREM2(high) macrophages and infarct border dynamics post-myocardial infarction.
MicroRNA-3473b regulates corticosterone-induced microglial polarization and inflammation through TREM2.
Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells-Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation.
VSIG2 as a novel immunosuppressive ligand interacts with Nectin-2 to regulate T cell responses.
Yueju pill and its active component- Myricetin attenuate the reinstatement of methamphetamine-seeking behavior in mice.
Ectomesenchymal Stem Cell Transplantation Induces Microglial Polarization and Anti-inflammatory IL-10 Secretion via NF-κB and MAPK Pathways to Mitigate Brain Injury Post-cerebral Hemorrhage.
Galectin-9 activates microglial asparagine endopeptidase and promotes α-synuclein pathology in Parkinson's disease.
The SARS-CoV-2 nucleocapsid protein induces microglia senescence-mediated cognitive impairment via Glycolysis.
SIRT1 Attenuates Neuropathic Pain via CDK5-Kalirin-7 Signaling Pathway in Type 2 Diabetic Rats.
More severe vascular remodeling in deep brain regions caused by hemodynamic differences is a potential mechanism of hypertensive cerebral small vessel disease.
The slow progression of Japanese encephalitis in aged mice is likely associated to B cell recruitment in the brain.
Mechanism of Dendrobium officinale polysaccharide in alleviating Alzheimer's disease: Insights from metabolomics, lipidomics, and proteomics analysis.
Synergistic microglial modulation by laminarin-based platinum nanozymes for potential intracerebral hemorrhage therapy.
Oseltamivir Phosphate Modulates CD24-Siglec-G/10 Interaction to Suppress Microglial-Driven Neuroinflammation After Cardiac Arrest.
Metformin promotes PEN2 expression to attenuate microglia-mediated neurotoxicity induced by HIV-1 Tat.
Mechanistic Study of Jaceosidin in Regulating Secondary Inflammation After Spinal Cord Injury in Mouse by Inhibiting PKM2 Activity.
The mechanism of Yizhi Qingxin formula to improve neuroinflammation in Alzheimer's disease by regulating the TLR4/NF‑κB/NLRP3 pathway.
Cerebral blood flow in elastin haploinsufficient and 3xTg-AD mice.
Monocyte-Platelet Aggregates Are Major Source of BDNF after Bacterial Stimulation of Human Peripheral Blood Immune Cells.
Salidroside improves blood-brain barrier integrity and cognitive function in hypobaric hypoxia mice by inhibiting microglia activation through GSK3β.
Recombinant human heavy-chain ferritin nanoparticles loaded with rosuvastatin attenuates secondary brain injury in intracerebral hemorrhage.
Mitochondrial respiratory complex IV deficiency recapitulates amyotrophic lateral sclerosis.
Inhibition of hippocampal mossy fiber plasticity and episodic memory by human Aβ oligomers is prevented by enhancing cAMP signaling in Alzheimer's mice.
Targeting ceramide-induced microglial pyroptosis: Icariin is a promising therapy for Alzheimer's disease.
Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia.
Photobiomodulation modulates mitochondrial energy metabolism and ameliorates neurological damage in an APP/PS1 mousmodel of Alzheimer's disease.
Green Tea Ameliorates Depression-Like Behavior and Cognitive Impairment Induced by High-Fat Diet and Chronic Mild Stress.
Luteolin attenuates cadmium neurotoxicity by suppressing glial inflammation and supporting neuronal survival.
Akkermansia muciniphila protects against dopamine neurotoxicity by modulating butyrate to inhibit microglia-mediated neuroinflammation.
Extracellular Vesicle-Liposome-Darunavir Formulation for the Treatment of HIV Neuropathogenesis.
Characterization of Chitinase 3-like protein 1 spatiotemporal distribution in human post-traumatic brain contusions and other neuropathological scenarios.
mtDNA-cGAS-STING axis-dependent NLRP3 inflammasome activation contributes to postoperative cognitive dysfunction induced by sevoflurane in mice.
(+)-Borneol inhibits neuroinflammation and M1 phenotype polarization of microglia in epileptogenesis through the TLR4-NFκB signaling pathway.
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice.
Profiling hypoxia signaling reveals a lncRNA signature contributing to immunosuppression in high-grade glioma.
Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease.
The CEBPB(+) glioblastoma subcluster specifically drives the formation of M2 tumor-associated macrophages to promote malignancy growth.
HGFIN deficiency exacerbates spinal cord injury by promoting inflammation and cell apoptosis through regulation of the PI3K/AKT signaling pathway.
Escitalopram moderately outperforms citalopram towards anti-neuroinflammation and neuroprotection in 6-hydroxydopamine-induced mouse model of Parkinson's disease.
Tyrosine phosphorylation and palmitoylation of TRPV2 ion channel tune microglial beta-amyloid peptide phagocytosis.
Regulation of leptin signaling and diet-induced obesity by SEL1L-HRD1 ER-associated degradation in POMC expressing neurons.
β-chitosan attenuates hepatic macrophage-driven inflammation and reverses aging-related cognitive impairment.
Ginsenoside compound K alleviates D-galactose-induced mild cognitive impairment by modulating gut microbiota-mediated short-chain fatty acid metabolism.
Stereotactically intracerebral transplantation of neural stem cells for ischemic stroke attenuated inflammatory responses and promoted neurogenesis: an experimental study with monkeys.
Rhein inhibits M1 polarization of BV2 microglia through MAPK/IκB signalling pathway and reduces neurotoxicity caused by neuroinflammation.
Targeting Mitochondrial Oxidative Stress to Protect Against Preterm Birth and Fetal Brain Injury via Nrf2 Induction.
ClassIIb histone deacetylase participates in perioperative neurocognitive disorders in elderly mice via HSP90/GR signaling pathway.
ADSC-derived exosomes provide neuroprotection in sepsis-associated encephalopathy by regulating hippocampal pyroptosis.
Choroid plexus CCL2‒CCR2 signaling orchestrates macrophage recruitment and cerebrospinal fluid hypersecretion in hydrocephalus.
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice.
Extracellular vesicles from neural stem cells safeguard neurons in intracerebral hemorrhage by suppressing reactive astrocyte neurotoxicity.
Electroacupuncture attenuates depressive-like behaviors in poststroke depression mice through promoting hippocampal neurogenesis and inhibiting TLR4/NF-κB/NLRP3 signaling pathway.
Remimazolam ameliorates postoperative cognitive dysfunction after deep hypothermic circulatory arrest through HMGB1-TLR4-NF-κB pathway.
Hic-5 antisense oligonucleotide inhibits advanced hepatic fibrosis and steatosis in vivo.
Single-cell transcriptomics reveals IRF7 regulation of the tumor microenvironment in isocitrate dehydrogenase wild-type glioma.
Immune-mediated impairment of tonic immobility defensive behavior in an experimental model of colonic inflammation.
Aged bone marrow macrophages drive systemic aging and age-related dysfunction via extracellular vesicle-mediated induction of paracrine senescence.
IDO-Kynurenine pathway mediates NLRP3 inflammasome activation-induced postoperative cognitive impairment in aged mice.
Neuroprotective effects of mesenchymal stromal cells in mouse models of Alzheimer's Disease: The Mediating role of gut microbes and their metabolites via the Microbiome-Gut-Brain axis.
Brain Resident Ly6C(hi) Monocytes Are Necessary for Maintaining Adult Hippocampal Neurogenesis.
Acupuncture Ameliorates Depression-Like Behaviors Through Modulating the Neuroinflammation Mediated by TLR4 Signaling Pathway in Rats Exposed to Chronic Restraint Stress.
Tonic excitation by astrocytic GABA causes neuropathic pain by augmenting neuronal activity and glucose metabolism.
Glucose-modified BSA/procyanidin C1 NPs penetrate the blood-brain barrier and alleviate neuroinflammation in Alzheimer's disease models.
MG53/GMs/HA-Dex neural scaffold promotes the functional recovery of spinal cord injury by alleviating neuroinflammation.
Modulation of Cerebrospinal Fluid Dysregulation via a SPAK and OSR1 Targeted Framework Nucleic Acid in Hydrocephalus.
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
CDDO, an Anti-Inflammatory and Antioxidant Compound, Attenuates Vasospasm and Neuronal Cell Apoptosis in Rats Subjected to Experimental Subarachnoid Hemorrhage.
Synergistic effect of mesenchymal stem cell-derived extracellular vesicle and miR-137 alleviates autism-like behaviors by modulating the NF-κB pathway.
MSC-derived exosomal miR-140-3p improves cognitive dysfunction in sepsis-associated encephalopathy by HMGB1 and S-lactoylglutathione metabolism.
RTA-408 Regulates p-NF-κB/TSLP/STAT5 Signaling to Ameliorate Nociceptive Hypersensitivity in Chronic Constriction Injury Rats.
Htr2b Promotes M1 Microglia Polarization and Neuroinflammation after Spinal Cord Injury via Inhibition of Neuregulin-1/ErbB Signaling.
Inhibiting the NLRP3 Inflammasome with MCC950 Alleviates Neurological Impairment in the Brain of EAE Mice.
Near-infrared light-activatable, analgesic nanocomposite delivery system for comprehensive therapy of diabetic wounds in rats.
Intracerebral hemorrhage-induced brain injury in mice: The role of peroxiredoxin 2-Toll-like receptor 4 inflammatory axis.
Human umbilical cord mesenchymal stem cell-derived exosomes attenuate neuroinflammation and oxidative stress through the NRF2/NF-κB/NLRP3 pathway.
Rasd1 is involved in white matter injury through neuron-oligodendrocyte communication after subarachnoid hemorrhage.
Novel perfluorocarbon-based oxygenation therapy alleviates Post-SAH hypoxic brain injury by inhibiting HIF-1α.
LncTCONS_00058568 is involved in the pathophysiologic processes mediated by P2X7R in the lower thoracic spinal cord after acute kidney injury.
Inhibition of repulsive guidance molecule-a ameliorates compromised blood-spinal cord barrier integrity associated with neuromyelitis optica in rats.
MyD88 Inhibition Attenuates Cerebral Ischemia-reperfusion Injury by Regulating the Inflammatory Response and Reducing Blood-brain Barrier Damage.
cGAS/STING signaling pathway-mediated microglial activation in the PFC underlies chronic ethanol exposure-induced anxiety-like behaviors in mice.
A disulfiram derivative against lung cancer via the Notch signaling pathway without neurotoxicity and hepatotoxicity.
The impact of Nrf2 knockout on the neuroprotective effects of dexmedetomidine in a mice model of cognitive impairment.
Echinatin alleviates inflammation and pyroptosis in hypoxic-ischemic brain damage by inhibiting TLR4/ NF-κB pathway.
Trilobatin suppresses aging-induced cognitive impairment by targeting SIRT2: Involvement of remodeling gut microbiota to mediate the brain-gut axis.
Disorder of neuroplasticity aggravates cognitive impairment via neuroinflammation associated with intestinal flora dysbiosis in chronic heart failure.
Melatonin Exerts an Anti-Panoptoic Role in Spinal Cord Ischemia-Reperfusion Injured Rats.
3-N-butylphthalide attenuates neuroinflammation in rotenone-induced Parkinson's disease models via the cGAS-STING pathway.
BAFF deficiency aggravated optic nerve crush-induced retinal ganglion cells damage by regulating apoptosis and neuroinflammation via NF-κB-IκBα signaling.
Based on spinal central sensitization creating analgesic screening approach to excavate anti-neuropathic pain ingredients of Corydalis yanhusuo W.T.Wang.
Extract of Astragali Radix and Solanum nigrum Linne regulates microglia and macrophage polarization and inhibits the growth and infiltration of C6 glioblastoma.
SEL1L-HRD1 ER-associated degradation regulates leptin receptor maturation and signaling in POMC neurons in diet-induced obesity.
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway.
The role of ApoE in fatty acid transport from neurons to astrocytes under ischemia/hypoxia conditions.
SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex.
Disease-Associated Neurotoxic Astrocyte Markers in Alzheimer Disease Based on Integrative Single-Nucleus RNA Sequencing.
Qualitative evaluations of reactive microglial heterogeneity in cultured porcine retina.
Neuroprotection of celastrol against postoperative cognitive dysfunction through dampening cGAS-STING signaling.
STING Driving Synaptic Phagocytosis of Hippocampal Microglia/Macrophages Contributes to Cognitive Impairment in Sepsis-Associated Encephalopathy in Mice.
Ginsenoside compound K alleviates brain aging by inhibiting ferroptosis through modulation of the ASK1-MKK7-JNK signaling pathway.
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
The microRNA-29ab1/Zfp36/AR Axis in the Hypothalamus Regulates Male-Typical Behaviors in Mice.
Liu-Shen-Wan inhibits PI3K/Akt and TRPV1 signaling alleviating bone cancer pain in rats.
Evaluation of the Neuroprotective Effect of Total Glycosides of Cistanche deserticola and Investigation of Novel Brain-Targeting Natural MAO-B Inhibitors.
TFEB signaling promotes autophagic degradation of NLRP3 to attenuate neuroinflammation in diabetic encephalopathy.
γ-Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer-Related Pathologies in a Mouse Model of Down Syndrome.
Propofol Mitigates Sepsis-Induced Brain Injury by Inhibiting Ferroptosis Via Activation of the Nrf2/HO-1axis.
Melatonin regulates microglial M1/M2 polarization via AMPKα2-mediated mitophagy in attenuating sepsis-associated encephalopathy.
Effects of nanoplastic exposure during pregnancy and lactation on neurodevelopment of rat offspring.
UAMC-3203 inhibits ferroptosis and promotes functional recovery in rats with spinal cord injury.
Effect of Scaffold Geometrical Structure on Macrophage Polarization during Bone Regeneration Using Honeycomb Tricalcium Phosphate.
Fisetin Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglia/Macrophage M1 Polarization and JAK2/STAT3 Signaling Pathway.
Mice with type I interferon signaling deficiency are prone to epilepsy upon HSV-1 infection.
Oral exposure of polystyrene microplastics and doxycycline affects mice neurological function via gut microbiota disruption: The orchestrating role of fecal microbiota transplantation.
Repetitive transcranial magnetic stimulation ameliorates cognitive deficits in mice with radiation-induced brain injury by attenuating microglial pyroptosis and promoting neurogenesis via BDNF pathway.
Enriched Environment Inhibits Neurotoxic Reactive Astrocytes via JAK2-STAT3 to Promote Glutamatergic Synaptogenesis and Cognitive Improvement in Chronic Cerebral Hypoperfusion Rats.
MiR-181c-5p ameliorates learning and memory in sleep-deprived mice via HMGB1/TLR4/NF-κB pathway.
PD-L1 promotes GSDMD-mediated NET release by maintaining the transcriptional activity of Stat3 in sepsis-associated encephalopathy.
Icariin reduces cognitive dysfunction induced by surgical trauma in aged rats by inhibiting hippocampal neuroinflammation.
Energy intake restriction significantly improves POCD after internal fixation of tibial fractures in mice.
Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression.
Neuroprotective Effects of Leptin on the APP/PS1 Alzheimer's Disease Mouse Model: Role of Microglial and Neuroinflammation.
IL-1β/IL-1R1 signaling is involved in the propagation of α-synuclein pathology of the gastrointestinal tract to the brain.
Biliverdin modulates the Nrf2/A20/eEF1A2 axis to alleviate cerebral ischemia-reperfusion injury by inhibiting pyroptosis.
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Clemastine fumarate attenuates tauopathy and meliorates cognition in hTau mice via autophagy enhancement.
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway.
Long-term normalization of calcineurin activity in model mice rescues Pin1 and attenuates Alzheimer's phenotypes without blocking peripheral T cell IL-2 response.
Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation.
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Aluminum exposure induces central nervous system impairment via activating NLRP3-medicated pyroptosis pathway.
NCBP1 Improves Cognitive Function in Mice by Reducing Oxidative Stress, Neuronal Loss, and Glial Activation After Status Epilepticus.
Multi-parametric MRI assessment of melatonin regulating the polarization of microglia in rats after cerebral ischemia/reperfusion injury.
The bexarotene derivative OAB-14 ameliorates cognitive decline in APP/PS1 transgenic mice by suppressing microglia-mediated neuroinflammation through the PPAR-γ pathway.
OTUD1 ameliorates cerebral ischemic injury through inhibiting inflammation by disrupting K63-linked deubiquitination of RIP2.
Nobiletin Mitigates D-Galactose-Induced Memory Impairment via Improving Hippocampal Neurogenesis in Mice.
Multi-omics analysis of a drug-induced model of bipolar disorder in zebrafish.
Adiponectin Attenuates Splenectomy-Induced Cognitive Deficits by Neuroinflammation and Oxidative Stress via TLR4/MyD88/NF-κb Signaling Pathway in Aged Rats.
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Deep Sc-RNA sequencing decoding the molecular dynamic architecture of the human retina.
Novel 2,6-disubstituted benzofuran-3-one analogues improve cerebral ischemia/reperfusion injury via neuroprotective and antioxidative effects.
Treatment with Granulocyte-Macrophage Colony-Stimulating Factor Reduces Viral Titers in the Brains of West Nile Virus-Infected Mice and Improves Survival.
Selective Targeting of Class I HDAC Reduces Microglial Inflammation in the Entorhinal Cortex of Young APP/PS1 Mice.
Neuronal loss of NCLX-dependent mitochondrial calcium efflux mediates age-associated cognitive decline.
Polydatin Alleviates Chronic Stress-Induced Depressive and Anxiety-like Behaviors in a Mouse Model.
Blocking Two-Pore Domain Potassium Channel TREK-1 Inhibits the Activation of A1-Like Reactive Astrocyte Through the NF-κB Signaling Pathway in a Rat Model of Major Depressive Disorder.
The internal ribosome entry site determines the neurotropic potential of enterovirus A71.
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Thymopentin (TP-5) prevents lipopolysaccharide-induced neuroinflammation and dopaminergic neuron injury by inhibiting the NF-κB/NLRP3 signaling pathway.
Intermittent hypoxia exacerbated depressive and anxiety-like behaviors in the bleomycin-induced pulmonary fibrosis mice.
Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice.
Emodin attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis.
Parthenolide alleviates microglia-mediated neuroinflammation via MAPK/TRIM31/NLRP3 signaling to ameliorate cognitive disorder.
ONO-2506 Can Delay Levodopa-induced Dyskinesia in the Early Stage.
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Heterozygous disruption of beclin 1 alleviates neurotoxicity induced by sub-chronic exposure of arsenite in mice.
Fra-1 induces apoptosis and neuroinflammation by targeting S100A8 to modulate TLR4 pathways in spinal cord ischemia/reperfusion injury.
Fingolimod ameliorates schizophrenia-like cognitive impairments induced by phencyclidine in male rats.
Microglia in Cultured Porcine Retina: Qualitative Immunohistochemical Analyses of Reactive Microglia in the Outer Retina.
Aluminum induces neuroinflammation via P2X7 receptor activating NLRP3 inflammasome pathway.
ASK1 inhibitor NQDI‑1 decreases oxidative stress and neuroapoptosis via the ASK1/p38 and JNK signaling pathway in early brain injury after subarachnoid hemorrhage in rats.
CXCR4 knockout induces neuropathological changes in the MPTP-lesioned model of Parkinson's disease.
Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke.
Prenatal Sevoflurane Exposure Impairs the Learning and Memory of Rat Offspring via HMGB1-Induced NLRP3/ASC Inflammasome Activation.
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Microglia trigger the structural plasticity of GABAergic neurons in the hippocampal CA1 region of a lipopolysaccharide-induced neuroinflammation model.
Antinociceptive and neuroprotective effect of echinacoside on peripheral neuropathic pain in mice through inhibiting P2X7R/FKN/CX3CR1 pathway.
Ischemic Preconditioning Alleviates Cerebral Ischemia-Reperfusion Injury by Interfering With Glycocalyx.
Spatiotemporal expression patterns of ZBP1 in the brain of mouse experimental stroke model.
Ilexchinene, a new seco-ursane triterpenoid from the leaves of Ilex chinensis with therapeutic effect on neuroinflammation by attenuating the MAPK/NF-κB signaling pathway.
Debris generated by laser and/or balloon cause cerebral infarction with different severity.
Metformin promotes Schwann cell remyelination, preserves neural tissue and improves functional recovery after spinal cord injury.
Cognitive Alterations in Old Mice Are Associated with Intestinal Barrier Dysfunction and Induced Toll-like Receptor 2 and 4 Signaling in Different Brain Regions.
Effects of Fisetin Treatment on Cellular Senescence of Various Tissues and Organs of Old Sheep.
Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition.
Ketogenic diet alleviates brain iron deposition and cognitive dysfunction via Nrf2-mediated ferroptosis pathway in APP/PS1 mouse.
Modulation of the endoplasmic reticulum stress and unfolded protein response mitigates the behavioral effects of early-life stress.
Poly-L-ornithine blocks the inhibitory effects of fibronectin on oligodendrocyte differentiation and promotes myelin repair.
Allograft inflammatory factor 1 is a potential diagnostic, immunological, and prognostic biomarker in pan-cancer.
Mitochondrial-targeting fluorescent small molecule IR-780 alleviates radiation-induced brain injury.
Ferulic acid produces neuroprotection against radiation-induced neuroinflammation by affecting NLRP3 inflammasome activation.
Probiotic Lactobacillus rhamnosus GR-1 supplementation attenuates Pb-induced learning and memory deficits by reshaping the gut microbiota.
Effects of Electroacupuncture on the Correlation between Serum and Central Immunity in AD Model Animals.
The Role of Microglia/Macrophages Activation and TLR4/NF-κB/MAPK Pathway in Distraction Spinal Cord Injury-Induced Inflammation.
Anomalous Levels of CD47/Signal Regulatory Protein Alpha in the Hippocampus Lead to Excess Microglial Engulfment in Mouse Model of Perioperative Neurocognitive Disorders.
Neuroinflammation in a Rat Model of Tourette Syndrome.
Transcranial near-infrared laser improves postoperative neurocognitive disorder in aged mice via SIRT3/AMPK/Nrf2 pathway.
Dexmedetomidine post-conditioning protects blood-brain barrier integrity by modulating microglia/macrophage polarization via inhibiting NF-κB signaling pathway in intracerebral hemorrhage.
Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.
Lipid profiles in the cerebrospinal fluid of rats with 6-hydroxydopamine-induced lesions as a model of Parkinson's disease.
LPS activates neuroinflammatory pathways to induce depression in Parkinson's disease-like condition.
α7 Nicotinic Acetylcholine Receptor May Be a Pharmacological Target for Perioperative Neurocognitive Disorders.
Acupuncture Ameliorates Depressive Behaviors by Modulating the Expression of Hippocampal Iba-1 and HMGB1 in Rats Exposed to Chronic Restraint Stress.
DAPT Attenuates Cadmium-Induced Toxicity in Mice by Inhibiting Inflammation and the Notch/HES-1 Signaling Axis.
Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice.
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Continuous theta-burst stimulation enhances and sustains neurogenesis following ischemic stroke.
Oral SARS-CoV-2 Inoculation Causes Nasal Viral Infection Leading to Olfactory Bulb Infection: An Experimental Study.
Intestinal Flora Composition Determines Microglia Activation and Improves Epileptic Episode Progress.
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Apelin-13 reduces lipopolysaccharide-induced neuroinflammation and cognitive impairment via promoting glucocorticoid receptor expression and nuclear translocation.
Celastrol inhibits pathologic neovascularization in oxygen-induced retinopathy by targeting the miR-17-5p/HIF-1α/VEGF pathway.
Panax notoginseng saponins alleviates inflammation induced by microglial activation and protects against ischemic brain injury via inhibiting HIF-1α/PKM2/STAT3 signaling.
Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2-Signal Transducer and Activator of Transcription 6 Pathway.
6-methoxyflavone suppresses neuroinflammation in lipopolysaccharide- stimulated microglia through the inhibition of TLR4/MyD88/p38 MAPK/NF-κB dependent pathways and the activation of HO-1/NQO-1 signaling.
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.
Genetic lesions of the noradrenergic system trigger induction of oxidative stress and inflammation in the ventral midbrain.
The effect of prolonged formalin fixation on the expression of proteins in human brain tissues.
Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation.
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Gut microbiota shapes social dominance through modulating HDAC2 in the medial prefrontal cortex.
Salidroside alleviates cadmium-induced toxicity in mice by restoring the notch/HES-1 and RIP1-driven inflammatory signaling axis.
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
Therapeutic Effect of Mitochondrial Division Inhibitor-1 (Mdivi-1) on Hyperglycemia-Exacerbated Early and Delayed Brain Injuries after Experimental Subarachnoid Hemorrhage.
Neuroglobin alleviates the neurotoxicity of sevoflurane to fetal rats by inhibiting neuroinflammation and affecting microglial polarization.
Ppp4r3a deficiency leads to depression-like behaviors in mice by modulating the synthesis of synaptic proteins.
Astragalin attenuates AlCl(3)/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation.
MG53 protein rejuvenates hUC-MSCs and facilitates their therapeutic effects in AD mice by activating Nrf2 signaling pathway.
Icariin attenuates ischaemic stroke through suppressing inflammation mediated by endoplasmic reticulum stress signalling pathway in rats.
Neuroprotective effects of CysLTR antagonist on Streptococcus pneumoniae-induced meningitis in rats.
Delayed administration of nafamostat mesylate inhibits thrombin-mediated blood-spinal cord barrier breakdown during acute spinal cord injury in rats.
Neonatal microglia and proteinase inhibitors-treated adult microglia improve traumatic brain injury in rats by resolving the neuroinflammation.
The intestinal microbial metabolite nicotinamide n-oxide prevents herpes simplex encephalitis via activating mitophagy in microglia.
Malignant Melanoma-Derived Exosomes Induce Endothelial Damage and Glial Activation on a Human BBB Chip Model.
Islet amyloid polypeptide cross-seeds tau and drives the neurofibrillary pathology in Alzheimer's disease.
2-PMAP Ameliorates Cerebral Vasospasm and Brain Injury after Subarachnoid Hemorrhage by Regulating Neuro-Inflammation in Rats.
Coeloglossum viride var. bracteatum extract attenuates Aβ-induced toxicity by inhibiting RIP1-driven inflammation and necroptosis.
Isoliquiritigenin attenuates neuroinflammation in mice model of Parkinson's disease by promoting Nrf2/NQO-1 pathway.
Neuroprotective effects of liraglutide against inflammation through the AMPK/NF-κB pathway in a mouse model of Parkinson's disease.
Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.
Connexin43 inhibition attenuated dopaminergic neuronal loss in the lipopolysaccharide-induced mice model of Parkinson's disease.
Neurotoxicological profile of the hallucinogenic compound 25I-NBOMe.
HIV-1 Tat drives the Fabp4/NF-κB feedback loop in microglia to mediate inflammatory response and neuronal apoptosis.
MMP-12 knockdown prevents secondary brain damage after ischemic stroke in mice.
Fluoxetine shows neuroprotective effects against LPS-induced neuroinflammation via the Notch signaling pathway.
Postmortem 7T MRI for guided histopathology and evaluation of cerebrovascular disease.
Aberrant neural activity in prefrontal pyramidal neurons lacking TDP-43 precedes neuron loss.
A pilot study: Gut microbiota, metabolism and inflammation in hypertensive intracerebral haemorrhage.
Blocking Hepatoma-Derived Growth Factor Attenuates Vasospasm and Neuron Cell Apoptosis in Rats Subjected to Subarachnoid Hemorrhage.
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
Photobiomodulation Therapy Attenuates Anxious-Depressive-Like Behavior in the TgF344 Rat Model.
Gut Microbiota Disorders Promote Inflammation and Aggravate Spinal Cord Injury Through the TLR4/MyD88 Signaling Pathway.
NU9056, a KAT 5 Inhibitor, Treatment Alleviates Brain Dysfunction by Inhibiting NLRP3 Inflammasome Activation, Affecting Gut Microbiota, and Derived Metabolites in LPS-Treated Mice.
Attenuation in Proinflammatory Factors and Reduction in Neuronal Cell Apoptosis and Cerebral Vasospasm by Minocycline during Early Phase after Subarachnoid Hemorrhage in the Rat.
Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood-brain barrier during kainic acid-induced brain damage.
Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells.
Isoliquiritigenin Confers Neuroprotection and Alleviates Amyloid-β42-Induced Neuroinflammation in Microglia by Regulating the Nrf2/NF-κB Signaling.
Class IIa HDAC Downregulation Contributes to Surgery-Induced Cognitive Impairment Through HMGB1-Mediated Inflammatory Response in the Hippocampi of Aged Mice.
Edaravone Plays Protective Effects on LPS-Induced Microglia by Switching M1/M2 Phenotypes and Regulating NLRP3 Inflammasome Activation.
Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer's-Like Pathology in the Hippocampus by Altering the Phenotype of Microglia in the APP/PS1 Mouse Model.
Catalytic patch with redox Cr/CeO(2) nanozyme of noninvasive intervention for brain trauma.
Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring.
Hypoxia-preconditioned mesenchymal stem cells attenuate microglial pyroptosis after intracerebral hemorrhage.
Edaravone attenuates cadmium-induced toxicity by inhibiting oxidative stress and inflammation in ICR mice.
Nilotinib inhibits microglia-mediated neuroinflammation to protect against dopaminergic neuronal death in Parkinson's disease models.
Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats.
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Bioinformatics analysis identifies CSF1R as an essential gene mediating Neuropathic pain - Experimental research.
Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.
TC10, a Rho family GTPase, is required for efficient axon regeneration in a neuron-autonomous manner.
A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota.
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Protective effects of melatonin on the white matter damage of neonatal rats by regulating NLRP3 inflammasome activity.
Edaravone attenuates H(2)O(2) or glutamate-induced toxicity in hippocampal neurons and improves AlCl(3)/D-galactose induced cognitive impairment in mice.
Increased Expression of Thymic Stromal Lymphopoietin in Chronic Constriction Injury of Rat Nerve.
Minocycline alleviates depression-like symptoms by rescuing decrease in neurogenesis in dorsal hippocampus via blocking microglia activation/phagocytosis.
Role of lipocalin-2 in extracellular peroxiredoxin 2-induced brain swelling, inflammation and neuronal death.
Adrenomedullin 2 attenuates LPS-induced inflammation in microglia cells by receptor-mediated cAMP-PKA pathway.
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Annexin A1 Attenuates Neutrophil Migration and IL-6 Expression through Fpr2 in a Mouse Model of Streptococcus suis-Induced Meningitis.
Gisenoside Rg1 attenuates cadmium-induced neurotoxicity in vitro and in vivo by attenuating oxidative stress and inflammation.
Schizandrin A ameliorates cognitive functions via modulating microglial polarisation in Alzheimer's disease mice.
Integration of Raman spectra with transcriptome data in glioblastoma multiforme defines tumour subtypes and predicts patient outcome.
Comprehensive transcriptomic characterization reveals core genes and module associated with immunological changes via 1619 samples of brain glioma.
Axl Alleviates Neuroinflammation and Delays Japanese Encephalitis Progression in Mice.
8-Formylophiopogonanone B antagonizes doxorubicin-induced cardiotoxicity by suppressing heme oxygenase-1-dependent myocardial inflammation and fibrosis.
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
Phytogalactolipid dLGG Inhibits Mouse Melanoma Brain Metastasis through Regulating Oxylipin Activity and Re-Programming Macrophage Polarity in the Tumor Microenvironment.
Phosphatase and Tensin Homolog Deleted on Chromosome Ten Knockdown Attenuates Cognitive Deficits by Inhibiting Neuroinflammation in a Mouse Model of Perioperative Neurocognitive Disorder.
Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage.
Microglia TREM2: A Potential Role in the Mechanism of Action of Electroacupuncture in an Alzheimer's Disease Animal Model.
Nrf2 Ablation Promotes Alzheimer's Disease-Like Pathology in APP/PS1 Transgenic Mice: The Role of Neuroinflammation and Oxidative Stress.
Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia.
Resveratrol Preincubation Enhances the Therapeutic Efficacy of hUC-MSCs by Improving Cell Migration and Modulating Neuroinflammation Mediated by MAPK Signaling in a Mouse Model of Alzheimer's Disease.
Bloodletting Puncture at Hand Twelve Jing-Well Points Improves Neurological Recovery by Ameliorating Acute Traumatic Brain Injury-Induced Coagulopathy in Mice.
Kalirin-7 contributes to type 2 diabetic neuropathic pain via the postsynaptic density-95/N-methyl-D-aspartate receptor 2B-dependent N-methyl-D-aspartate receptor 2B phosphorylation in the spinal cord in rats.
Caveolin-1 in spinal cord modulates type-2 diabetic neuropathic pain through the Rac1/NOX2/NR2B signaling pathway.
FTY720 Prevents Spatial Memory Impairment in a Rat Model of Chronic Cerebral Hypoperfusion via a SIRT3-Independent Pathway.
LongShengZhi Capsule Attenuates Alzheimer-Like Pathology in APP/PS1 Double Transgenic Mice by Reducing Neuronal Oxidative Stress and Inflammation.
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Glucagon-like peptide-1 receptor agonist Exendin-4 improves neurological outcomes by attenuating TBI- induced inflammatory responses and MAPK activation in rats.
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat.
MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis.
Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain.
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage.
IL-1β/IL-1R1 signaling induced by intranasal lipopolysaccharide infusion regulates alpha-Synuclein pathology in the olfactory bulb, substantia nigra and striatum.
Morphological analyzes of microglia heterogeneity and dynamics during photoreceptor degeneration in vitro: Presumptive dark microglia in porcine retina.
Attenuation of Acute Intracerebral Hemorrhage-Induced Microglial Activation and Neuronal Death Mediated by the Blockade of Metabotropic Glutamate Receptor 5 In Vivo.
Changes in macrophage inflammatory protein-1 (MIP-1) family members expression induced by traumatic brain injury in mice.
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Carbon dot targeting to nitrogen signaling molecules for inhibiting neuronal death.
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression.
Natural Xanthone α-Mangostin Inhibits LPS-Induced Microglial Inflammatory Responses and Memory Impairment by Blocking the TAK1/NF-κB Signaling Pathway.
Effects of Exercise Training on Anxious-Depressive-like Behavior in Alzheimer Rat.
Over-Expression of Allograft Inflammatory Factor-1 (AIF-1) in Patients with Rheumatoid Arthritis.
Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage.
BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease.
Synaptic alterations and immune response are sexually dimorphic in a non-pertussis toxin model of experimental autoimmune encephalomyelitis.
Scorpion alleviates bone cancer pain through inhibition of bone destruction and glia activation.
Protective role of cinnabar and realgar in Hua-Feng-Dan against LPS plus rotenone-induced neurotoxicity and disturbance of gut microbiota in rats.
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Photobiomodulation therapy for repeated closed head injury in rats.
Acetate attenuates perioperative neurocognitive disorders in aged mice.
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Menthol protects dopaminergic neurons against inflammation-mediated damage in lipopolysaccharide (LPS)-Evoked model of Parkinson's disease.
Glutathione Depletion and Parkinsonian Neurotoxin MPP(+)-Induced TRPM2 Channel Activation Play Central Roles in Oxidative Cytotoxicity and Inflammation in Microglia.
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
CCR4 antagonist (C021) influences the level of nociceptive factors and enhances the analgesic potency of morphine in a rat model of neuropathic pain.
Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages.
Cu(II) disrupts autophagy-mediated lysosomal degradation of oligomeric Aβ in microglia via mTOR-TFEB pathway.
Mefenamic acid can attenuate depressive symptoms by suppressing microglia activation induced upon chronic stress.
Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation.
The blockade of CC chemokine receptor type 1 influences the level of nociceptive factors and enhances opioid analgesic potency in a rat model of neuropathic pain.
Intracerebral Hemorrhage-Induced Brain Injury in Rats: the Role of Extracellular Peroxiredoxin 2.
Interferon-λ Attenuates Rabies Virus Infection by Inducing Interferon-Stimulated Genes and Alleviating Neurological Inflammation.
[Establishment of a vimentin knockout and HIV-1 gp120 transgenic mouse model].
H(2)S attenuates injury after ischemic stroke by diminishing the assembly of CaMKII with ASK1-MKK3-p38 signaling module.
Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury.
Expression of cysteinyl leukotriene receptor in brain tissues of rats with Streptococcus pneumoniae meningitis.
Naringenin Produces Neuroprotection Against LPS-Induced Dopamine Neurotoxicity via the Inhibition of Microglial NLRP3 Inflammasome Activation.
Pharmacological Blockade of Spinal CXCL3/CXCR2 Signaling by NVP CXCR2 20, a Selective CXCR2 Antagonist, Reduces Neuropathic Pain Following Peripheral Nerve Injury.
Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis.
Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet.
Intracerebroventricular administration of lupus serum induces microglia activation and leukocyte adhesion in the cerebromicrovasculature of mice.
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Farrerol protects dopaminergic neurons in a rat model of lipopolysaccharide-induced Parkinson's disease by suppressing the activation of the AKT and NF-κB signaling pathways.
Nanozyme-Based Bandage with Single-Atom Catalysis for Brain Trauma.
TREM2 deficiency aggravates α-synuclein-induced neurodegeneration and neuroinflammation in Parkinson's disease models.
Splicing repression is a major function of TDP-43 in motor neurons.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1.
Complement Inhibition Attenuates Early Erythrolysis in the Hematoma and Brain Injury in Aged Rats.
Naringenin targets on astroglial Nrf2 to support dopaminergic neurons.
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Redox Trimetallic Nanozyme with Neutral Environment Preference for Brain Injury.
Microglia as modulators of exosomal alpha-synuclein transmission.
Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway.
Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor.
MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo.
Maternal separation disturbs postnatal development of the medial prefrontal cortex and affects the number of neurons and glial cells in adolescent rats.
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats.
Involvement of Macrophage Inflammatory Protein-1 Family Members in the Development of Diabetic Neuropathy and Their Contribution to Effectiveness of Morphine.
Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3β-Nrf2/NF-κB Signaling Axis.
Allograft Inflammatory Factor-1 Mediates Macrophage-Induced Impairment of Insulin Signaling in Adipocytes.
Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures.
Differential Regulation of Adhesion and Phagocytosis of Resting and Activated Microglia by Dopamine.
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Meloxicam Improves Cognitive Impairment of Diabetic Rats through COX2-PGE2-EPs-cAMP/pPKA Pathway.
Pharmacological blockade of CXCR3 by (±)-NBI-74330 reduces neuropathic pain and enhances opioid effectiveness - Evidence from in vivo and in vitro studies.
Zaprinast diminished pain and enhanced opioid analgesia in a rat neuropathic pain model.
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
[Role of allograft inflammatory factor-1 in regulating the proliferation, migration and apoptosis of colorectal cancer cells].
Combination Treatment with Methylene Blue and Hypothermia in Global Cerebral Ischemia.
A model to study complement involvement in experimental retinal degeneration.
CD4+ αβ T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries.
Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways.
Early Postnatal Exposure to Airborne Fine Particulate Matter Induces Autism-like Phenotypes in Male Rats.
Notch Signaling Regulates Microglial Activation and Inflammatory Reactions in a Rat Model of Temporal Lobe Epilepsy.
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Glia maturation factor beta is required for reactive gliosis after traumatic brain injury in zebrafish.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis.
Lipopolysaccharide from Rhodobacter sphaeroides (TLR4 antagonist) attenuates hypersensitivity and modulates nociceptive factors.
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Involvement of microglial cells in the antinociceptive effects of metamizol in a mouse model of neuropathic pain.
Upregulation of allograft inflammatory factor‑1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype.
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model.
Colony-stimulating factor-1-induced AIF1 expression in tumor-associated macrophages enhances the progression of hepatocellular carcinoma.
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Ketamine Alleviates Depressive-Like Behaviors via Down-Regulating Inflammatory Cytokines Induced by Chronic Restraint Stress in Mice.
Intranasal Delivery of a Caspase-1 Inhibitor in the Treatment of Global Cerebral Ischemia.
The RS504393 Influences the Level of Nociceptive Factors and Enhances Opioid Analgesic Potency in Neuropathic Rats.
Licochalcone A Prevents the Loss of Dopaminergic Neurons by Inhibiting Microglial Activation in Lipopolysaccharide (LPS)-Induced Parkinson's Disease Models.
Spinal CCL1/CCR8 signaling interplay as a potential therapeutic target - Evidence from a mouse diabetic neuropathy model.
Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.
Silk fibroin-Pellethane® cardiovascular patches: Effect of silk fibroin concentration on vascular remodeling in rat model.
Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat.
Fingolimod (FTY720) attenuates social deficits, learning and memory impairments, neuronal loss and neuroinflammation in the rat model of autism.
Antibody incubation at 37°C improves fluorescent immunolabeling in free-floating thick tissue sections.
Sarsasapogenin-AA13 ameliorates Aβ-induced cognitive deficits via improving neuroglial capacity on Aβ clearance and antiinflammation.
Adenosine production by brain cells.
CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke.
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
Ginsenoside Rg1 protects against sepsis-associated encephalopathy through beclin 1-independent autophagy in mice.
Early start of progressive motor deficits in Line 61 α-synuclein transgenic mice.
Bexarotene protects against traumatic brain injury in mice partially through apolipoprotein E.
Vanillin Protects Dopaminergic Neurons against Inflammation-Mediated Cell Death by Inhibiting ERK1/2, P38 and the NF-κB Signaling Pathway.
Galangin Reduces the Loss of Dopaminergic Neurons in an LPS-Evoked Model of Parkinson's Disease in Rats.
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Gypenoside Attenuates β Amyloid-Induced Inflammation in N9 Microglial Cells via SOCS1 Signaling.
Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model.
Regulation and role of ERK phosphorylation in glial cells following a nigrostriatal pathway injury.
Trans-cinnamaldehyde improves memory impairment by blocking microglial activation through the destabilization of iNOS mRNA in mice challenged with lipopolysaccharide.
Participation of pro- and anti-nociceptive interleukins in botulinum toxin A-induced analgesia in a rat model of neuropathic pain.
Methylene Blue promotes cortical neurogenesis and ameliorates behavioral deficit after photothrombotic stroke in rats.
Impact of acquired and innate immunity on spinal cord ischemia and reperfusion injury.
Blockade of IL-18 signaling diminished neuropathic pain and enhanced the efficacy of morphine and buprenorphine.
Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model.
Expression of allograft inflammatory factor-1 in peripheral blood monocytes and synovial membranes in patients with rheumatoid arthritis.
Beneficial properties of maraviroc on neuropathic pain development and opioid effectiveness in rats.
Treatment with a carbon monoxide-releasing molecule (CORM-2) inhibits neuropathic pain and enhances opioid effectiveness in rats.
Intrathecal Injection of Human Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorates Neuropathic Pain in Rats.
Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy.
NOD2 is involved in the inflammatory response after cerebral ischemia-reperfusion injury and triggers NADPH oxidase 2-derived reactive oxygen species.
Intervention with exercise restores motor deficits but not nigrostriatal loss in a progressive MPTP mouse model of Parkinson's disease.
Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson's disease models are mediated by GPR109A-dependent mechanisms.
The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain.
Targeting the CD80/CD86 costimulatory pathway with CTLA4-Ig directs microglia toward a repair phenotype and promotes axonal outgrowth.
Chronic Noise Exposure Acts Cumulatively to Exacerbate Alzheimer's Disease-Like Amyloid-β Pathology and Neuroinflammation in the Rat Hippocampus.
Minocycline enhances the effectiveness of nociceptin/orphanin FQ during neuropathic pain.
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.
Photoreceptor degeneration, structural remodeling and glial activation: a morphological study on a genetic mouse model for pericyte deficiency.
Genetics of gene expression characterizes response to selective breeding for alcohol preference.
Cold-inducible RNA-binding protein mediates neuroinflammation in cerebral ischemia.
Peripheral immunomodulation with ginsenoside Rg1 ameliorates neuroinflammation-induced behavioral deficits in rats.
Involvement of pro- and antinociceptive factors in minocycline analgesia in rat neuropathic pain model.
Maternal bisphenol a diet induces anxiety-like behavior in female juvenile with neuroimmune activation.
Minocycline influences the anti-inflammatory interleukins and enhances the effectiveness of morphine under mice diabetic neuropathy.
ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy.
Intraperitoneal administration of AAV9-shRNA inhibits target gene expression in the dorsal root ganglia of neonatal mice.
Time course and progression of wild type α-synuclein accumulation in a transgenic mouse model.
Effects of selective and non-selective inhibitors of nitric oxide synthase on morphine- and endomorphin-1-induced analgesia in acute and neuropathic pain in rats.
Involvement of extraneural tissues and upregulation of inducible nitric oxide synthase after experimental infection with rabies virus in BALB/c mice and LEW/SsN rats.
The dynamic expression of allograft inflammatory factor-1 in hepatic tissues and splenic cells of BALB/c mice with Schistosoma japonicum infection.
Daintain/AIF-1 promotes breast cancer cell migration by up-regulated TNF-α via activate p38 MAPK signaling pathway.
17β-Estradiol increased the expression of daintain/AIF-1 in RAW264.7 macrophages.
Costachescu I, Gogu RM, Stanciu GD, Solcan C, Horodincu L, Szilagyi A, Craciun VC, Ababei DC, Tamba BI
Frontiers in pharmacology 2026;17:1761426
Frontiers in pharmacology 2026;17:1761426
Rosuvastatin attenuates blood-brain barrier dysfunction after ICH through modulation of CXCL12-associated VEGFR2/p38 MAPK signaling.
Yuan M, Zhou H, Pan H, Xiao Z, Wu H, Wu W
Neuropharmacology 2026 Sep 1;295:110998
Neuropharmacology 2026 Sep 1;295:110998
Stem Cell-Derived Exosomes Improve Neurological Dysfunction in a Rat Model of Moderate-to-Severe Cerebral Palsy.
Peng T Jr, Lin H, Zeng X, Xie Y, Luo J, Zhang L, Huang S, Ye Z, Guo X, Le W, Zhang M, Li W, Peng T Sr, Liu L, Han M, Gao T, Tang H, Zhang J, He L, Xu K
Stem cell reviews and reports 2026 May;22(4):1865-1885
Stem cell reviews and reports 2026 May;22(4):1865-1885
Flavonoids of Ziziphora clinopodioides improve Alzheimer's cognitive impairment and inhibit NLRP3 inflammasome activation via autophagy-lysosome pathway.
Gu L, Liu J, Shan X, Li S, Zheng M, Wang C, Tan Y, Zhuo X, Li Q, Yang W, Zhang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158028
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158028
Glaucine suppresses IL-16/CD4 to alleviate neuropathic pain via spinal p56(lck)-NMDA receptor signaling.
Li X, Wang R, Ma X, Yang J, Zhang S, Zhang Z, Jiang H, Liu J, Yu B, Dai W
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar;399(5):6485-6500
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar;399(5):6485-6500
Thymic stromal lymphopoietin modification gates chronic pain via regulation of transient receptor potential vanilloid type 1-caspase1.
Lu YY, Lu CC, Tsai HP, Wu CH
The International journal of neuroscience 2026 Mar;136(3):309-317
The International journal of neuroscience 2026 Mar;136(3):309-317
PROTAC-Mediated Degradation of mHTT Aggregates Attenuates Neurotoxicity in Cellular and R6/2 Mouse Models of Huntington's Disease.
Lu PC, Huang YA, Wali N, Tseng MC, He RY, Chern Y, Wei TT, Shie JJ, Huang JJ
Journal of the American Chemical Society 2026 Mar 4;148(8):8107-8121
Journal of the American Chemical Society 2026 Mar 4;148(8):8107-8121
Integrated stress response inhibition rescues inflammation-associated accelerated forgetting of recognition memory in mice.
Liu SY, Zuo Y, Jin X, Kuang X, Tian SW
Psychopharmacology 2026 Mar 23;
Psychopharmacology 2026 Mar 23;
Sphingosine-1-Phosphate Receptor 3 Mediated Neuroinflammation is Critically Involved in the Development of Brain Injury Following Cardiac Arrest in Mice.
Wang X, Cai SQ, Gao Y, Fan JJ, Ren LW, Gao HC, Chen XD, Duan ML
Neurochemical research 2026 Mar 19;51(2)
Neurochemical research 2026 Mar 19;51(2)
Modulating GRP75 to restore calcium homeostasis: a novel neuroprotective strategy of CRSE6(#) in Parkinson's disease models.
Wang X, Li S, Xiang X, Zhang X, Yu C, Qing D, Law BY, Tang Y
Journal of advanced research 2026 Mar 19;
Journal of advanced research 2026 Mar 19;
A Ratiometric Afterglow Luminescence Probe for in Vivo Imaging of Neuroinflammation in Traumatic Brain Injury.
Deng L, Xiang J, Zeng X, Li Z, Chen Z, Zhang C, He H, Ye T, Gong Q, Song G, Liang C
Analytical chemistry 2026 Mar 17;98(10):7877-7887
Analytical chemistry 2026 Mar 17;98(10):7877-7887
Blood-brain barrier-penetrative lipid nanoparticles enable systemic delivery of TRIM11 mRNA to disaggregate Tau in Alzheimer's disease models.
Zou Y, Sang Y, Zheng M, Shi B
Cell reports. Medicine 2026 Mar 17;7(3):102685
Cell reports. Medicine 2026 Mar 17;7(3):102685
Tanshinone IIA-pretreated mesenchymal stem cells alleviate neuroinflammation in 3×Tg-AD mice via the TREM2/PI3K/Akt pathway.
Wu J, Ge Y, Zhang L, Huang J, Huang N, Luo Y
Stem cell research & therapy 2026 Mar 17;17(1)
Stem cell research & therapy 2026 Mar 17;17(1)
Evodiamine alleviates MPTP-induced Parkinson's disease in mice by regulating gut microbiota and suppressing TLR4/MyD88/NF-kB pathway.
Wang S, Zhu Y, Wang J, Jin W, Li N, Li Z, Chang Y, Jiang C, Wang T
Scientific reports 2026 Mar 13;16(1)
Scientific reports 2026 Mar 13;16(1)
The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease.
Yue M, Chen T, Chen W, Wei J, Liao B, Zhang J, Li F, Hong D, Fang X
Neural regeneration research 2026 Mar 1;21(3):1211-1221
Neural regeneration research 2026 Mar 1;21(3):1211-1221
M2 macrophage-derived exosomes delivering haptoglobin and interleukin-10 plasmids for synergistic therapy of intracerebral hemorrhage.
Wang K, Li J, He M, Wang L, Guo X, Zhou S
Bioactive materials 2026 Jun;60:510-526
Bioactive materials 2026 Jun;60:510-526
Triamcinolone acetonide nanoparticles ameliorate interstitial cystitis and anxiety/depression by targeting the bladder-metabolic-brain axis.
Liu Z, Ju Q, Yang Y, Lu Q, Huang R, Yang J, Bao Y, Jiang T, Peng Y, Liu Y, Zhang D, Shen W
Materials today. Bio 2026 Jun;38:103112
Materials today. Bio 2026 Jun;38:103112
Electroacupuncture as a promising therapeutic strategy for chronic constriction injury-induced neuropathic pain: Insights into the PPARα/SIRT1/NF-κB axis.
Jia P, Chen Y, Wu Q, Zhang R, Jabeen T, Du Y, Lei L, Duan S, Chen A, Yin L, Jiang S
Colloids and surfaces. B, Biointerfaces 2026 Jun;262:115546
Colloids and surfaces. B, Biointerfaces 2026 Jun;262:115546
Dynamic expression of type III collagen in the lesion core of post-ischemic brain colocalizing with angiogenesis and lipid droplets during fibrotic scar formation.
Mutoh T, Kitajo K, Yamaguchi A
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Jan;46(1):134-150
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Jan;46(1):134-150
Japanese encephalitis virus activates the NLRP3/caspase-1/GSDMD signaling pathway in dopaminergic neurons.
Guo X, Lu S, Huang Z, Li J, Cheng G, Hu X, Zhang W, Gu C
PLoS neglected tropical diseases 2026 Jan;20(1):e0013924
PLoS neglected tropical diseases 2026 Jan;20(1):e0013924
Chronic Stress Leads to Time-Dependent Bone Loss Through HPA Axis Dysregulation and GR Nuclear Translocation Disorder.
Yan Y, Li J, Lu Z, Zhang Z, Hao G, Zhao Y, Liu H, Liu Y, Bao X, Duan M, Li Y
International journal of molecular sciences 2026 Jan 31;27(3)
International journal of molecular sciences 2026 Jan 31;27(3)
Sodium tanshinone IIA sulfonate alleviates neuroinflammation-induced damage to hippocampal neurons by activating SIRT1 in mice with sepsis-associated encephalopathy.
Song Y, Lin W, Yuan H, Hu H, Wu S, Lu Y, Li D, Jing L, Tu S, Zhu W
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120731
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120731
Glycyrrhizic acid-loaded biomimetic hybrid liposomes targeting inflammatory cascades and PD-1/PD-L1 pathway to reverse neuroinflammation-driven cognitive decline.
Wang Y, Luo F, Zhang P, Niu H, Tan Y, Zhang Y, Tang Z, Du L, Jin Y, Jin X
Materials today. Bio 2026 Feb;36:102657
Materials today. Bio 2026 Feb;36:102657
Reducing Neuroinflammation via Inhibition of Fibrinogen Deposition and Microglial Activation as an Underlying Mechanism of Paning I Decoction in Ameliorating Parkinson's Disease Symptoms.
Chen YJ, Chen JW, Xie MR, Wang RZ, Wan YL, Zeng J, Zhong BW, Zhou SQ, Liu F
Immunity, inflammation and disease 2026 Feb;14(2):e70310
Immunity, inflammation and disease 2026 Feb;14(2):e70310
Nighttime-restricted feeding disrupts spermatogenesis in mice via gut microbiota-derived KYNA homeostasis.
Yang D, Xie D, Li C, Liu Y, Cheng X, Liu J, Lu Q, Jia L, Liu W, Luo Q, Chen Z, Huang C
Communications biology 2026 Feb 3;9(1)
Communications biology 2026 Feb 3;9(1)
Roflumilast Elicits Therapeutic and Neuroprotective Effects in 3-Nitropropionic Acid-Induced Huntington's Disease-Like Neurodegeneration in Rats by Mitigating NLRP3 Inflammasome-Mediated Pyroptosis, Ferroptosis, and Glial Activation.
Taha M, Salah D, Abdou K, Senousy MA
Neurochemical research 2026 Feb 28;51(2)
Neurochemical research 2026 Feb 28;51(2)
Machine learning-guided Huanglian Jiedu decoction targets STING in periodontitis-induced Alzheimer's Disease.
Li J, Chen M, Ren P, Sun G, Zhong F, Zhu Y, Li G, Fan Y, Chen J, Xu M, Qiao M, Zhao G, Xu Y, Wu W
NPJ digital medicine 2026 Feb 27;9(1)
NPJ digital medicine 2026 Feb 27;9(1)
High-intensity interval training remodels perineuronal nets in the medial prefrontal cortex to drive microglial polarization and alleviate osteoarthritis pain.
Lin C, Zhang X, Ye Z, Zhou F, Huang K, Zhu S, Chen A, Li X
Scientific reports 2026 Feb 20;16(1)
Scientific reports 2026 Feb 20;16(1)
NIR-II-Responsive Biomimetic Nanoplatform for Precise Inhibition of Ischemic Stroke via Dual Modulation of Ion Channels and Microglia.
Liu X, Wu Z, Lv H, Li B, Li C, Zhao J, Li S, Zhang H, Zhang H, Xing C
ACS applied materials & interfaces 2026 Feb 18;18(6):9497-9511
ACS applied materials & interfaces 2026 Feb 18;18(6):9497-9511
Luteolin-Loaded TGN/RAP12 Dual-Peptide Functionalized Nanoparticles: Synergistic Enhancement of BBB Penetration and Microglia Targeting in Alzheimer's Disease.
Liu S, Xing Y, Na Y, Wu H, Liu C, Wang Z, Zhang N, Wu X, Geng F
Molecules (Basel, Switzerland) 2026 Feb 15;31(4)
Molecules (Basel, Switzerland) 2026 Feb 15;31(4)
Neuro-bone-skin tri-regeneration via a microenvironment-responsive PRP-loaded chitosan hydrogel for traumatic brain injury therapy.
Yang W, Su Y, Wang H, Liu P, Cheng P, Zhao H, He Y, Liu Y, Ma S, Guan F, Yao M
Materials today. Bio 2026 Apr;37:102913
Materials today. Bio 2026 Apr;37:102913
Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.
Li Y, Hu J, Ran B, Zhong H, Zhong N, Zhong Y, Fu X, Liu X, Wu G, Zhong Q, Li J
Materials today. Bio 2026 Apr;37:102783
Materials today. Bio 2026 Apr;37:102783
Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury.
Li X, Ye J, Zhong D, Xie J, Ding Z, Zhou M
Biomaterials 2026 Apr;327:123767
Biomaterials 2026 Apr;327:123767
RUVBL2 Regulates Microglia Metabolic Reprogramming to Mediate Stress Granules Aggregation Exacerbating Postoperative Delirium in Aged Mild Cognitive Impairment Rats.
Zhang L, Wang Z, Yang C, Wang X, Liu X, Zhang H, Liu H, Liao H, Chen J, Wang H
Aging cell 2026 Apr;25(4):e70458
Aging cell 2026 Apr;25(4):e70458
IMR-1 ameliorates perinatal LPS-induced brain injury by promoting the conversion of glial cells into neurons.
Tang J, Zhou S, Zhang Z, Duan B, Xu Y
Journal of molecular histology 2026 Apr 27;57(3)
Journal of molecular histology 2026 Apr 27;57(3)
Auditory activity sustains adult neurogenesis and cognition through the locus coeruleus-norepinephrine system.
Liu Q, Luo X, Liang Z, Qin D, Wang M, Guo W
Cell stem cell 2026 Apr 2;33(4):605-621.e6
Cell stem cell 2026 Apr 2;33(4):605-621.e6
Propionate Aggravates Anxiety and Cognitive Dysfunction in High-Fat Diet Mice by Activating Hippocampal Microglia-Mediated Neuroinflammation.
Zuo X, Bai H, Zhao Q, Zhao X, Feng X
ACS chemical neuroscience 2026 Apr 15;17(8):1566-1578
ACS chemical neuroscience 2026 Apr 15;17(8):1566-1578
Platelet factors 4 produces an antidepressant effect in mice via inhibition of neuroinflammation.
Li YH, Zhan JQ, Zhao Y, Ouyang ZY, Luo LQ, Wei B, Yang YJ
Journal of advanced research 2026 Apr 15;
Journal of advanced research 2026 Apr 15;
Spermidine Attenuates Neuroimmune Dysfunction in Gulf War Illness via Modulation of the Gut- Brain Axis.
Trivedi A, Roy S, More M, Bose D, Saha P, Kumar R, Sarkar S, Skupsky J, Tuteja A, Sullivan K, Klimas N, Chatterjee S
Molecular neurobiology 2026 Apr 10;63(1)
Molecular neurobiology 2026 Apr 10;63(1)
Thalamic glutamatergic neurons regulate seizure onset and generalization in temporal lobe epilepsy.
Liang S, Han Y, Wang J, Liu L, Zhu M, Zhang M, Sun Z, Zhang X, Wang Y, Sun Y
Cell reports 2026 Apr 10;45(4):117246
Cell reports 2026 Apr 10;45(4):117246
Naltrexone treatment improves anxiety- and depression-like behavior in alcohol-exposed mice.
Yang S, Tong L, Zhang L, Cui R, Lyu X, He L, Liu H
Behavioural pharmacology 2026 Apr 1;37(2):117-125
Behavioural pharmacology 2026 Apr 1;37(2):117-125
Lipofuscin autofluorescence confounds intracellular amyloid β detection in the aged mouse brain.
Dougnon G, Matsui H
Aging brain 2025;8:100148
Aging brain 2025;8:100148
Glutathione metabolism as a key regulator of oxidative hippocampal injury in sepsis-associated encephalopathy: an integrated proteomics and metabolomics study.
Li Y, Wang L, Ma T, Peng T, Wang L, Wang J, Li Y, Wang Y
Frontiers in neuroscience 2025;19:1671955
Frontiers in neuroscience 2025;19:1671955
Coixol ameliorates dopaminergic neurodegeneration by inhibiting neuroinflammation and protecting mitochondrial function.
Yang S, Han J, Xue M, Zhang Y, Yan A, Gao X, He J, Sun X, Fu S, Liu D, Huang B
Frontiers in pharmacology 2025;16:1657910
Frontiers in pharmacology 2025;16:1657910
The protective effect of Blautia coccoides in secondary injury of intracerebral hemorrhage.
Shao X, Zheng M, Ye C, Lu J, Li M, Su K, Lin H, He L, Qi X, Wang J
Frontiers in microbiology 2025;16:1616222
Frontiers in microbiology 2025;16:1616222
Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.
Zhang Y, Wu Q, Pan Y, Xin M, Wang W, Zhai X, Zhou P, Zhang C, Wang Y
Frontiers in pharmacology 2025;16:1596087
Frontiers in pharmacology 2025;16:1596087
Effect of Fangxia-Dihuang Decoction on doxorubicin-induced cognitive impairment in breast cancer animal model.
Wang X, Sun Q, Li J, Lai B, Pei X, Chen N
Frontiers in oncology 2025;15:1515498
Frontiers in oncology 2025;15:1515498
Madecassoside exerts anti-neurodegeneration effects in protein l-isoaspartyl methyltransferase deficient mice via targeting PRDX2-mediated oxidative stress and inflammation.
Zhong W, Zhu G, Lu D, Wang L, Zhang B, Su Z, Qin Z
Biochemical pharmacology 2025 Sep;239:117034
Biochemical pharmacology 2025 Sep;239:117034
Refinement of TSLP expression mediates chronic allodynia associated with IL22/STAT3 axis.
Lu CC, Lu YY, Tsai HP, Wu CH
Neurochemistry international 2025 Sep;188:106022
Neurochemistry international 2025 Sep;188:106022
Thiamet-G ameliorates Parkinson's disease-associated cognitive impairment via increasing O-GlcNAcylation of STING in the microglia.
Zhu S, Wang N, Chen S, Zou J, Tan S
Neurochemistry international 2025 Sep;188:106014
Neurochemistry international 2025 Sep;188:106014
Huangqi Guizhi Wuwu decoction alleviate Oxaliplatin-Induced Peripheral Neuropathy by adjusting the myelin regeneration.
Yang X, Zhu H, Li Z, Wang Q, Gao Y, Li Z, Tao L, Li L, Sun D, Zhang L, Shen W, Cheng H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157039
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157039
Nicotinamide Riboside Alleviates the Neurotoxic Injury of Dendritic Spine Plasticity Mediated by Hypoxic Microglial Activation.
Hou J, Zhang H, Huo X, Guan R, Wang B, Wang Y, Zhao F, Liu X, Hu Y, Zhuang C, Zou Y
Biomolecules 2025 Sep 30;15(10)
Biomolecules 2025 Sep 30;15(10)
Aging-related decline in the liver and brain is accelerated by refined diet consumption.
Kromm F, Bozkir HÖ, Brandt A, Yergaliyev T, Camarinha-Silva A, Bergheim I
GeroScience 2025 Sep 26;
GeroScience 2025 Sep 26;
Human brain cell types shape host-rabies virus transcriptional interactions revealing a preexisting pro-viral astrocyte subpopulation.
Feige L, Young K, Cerapio JP, Kozaki T, Kergoat L, Libri V, Ginhoux F, Hasan M, Ben Ameur L, Chin G, Goode Z, Bourhy H, Saunders A
Cell reports 2025 Sep 23;44(9):116159
Cell reports 2025 Sep 23;44(9):116159
Dectin-1 Drives Diabetic Retinopathy via Inducing Microglia-Mediated Inflammation and Blood-Retinal Barrier Breakdown.
Zhang L, Zhang S, Li Y, Yang Z, Hu W, Bai H, Zhou W, Wang Z, Li M, Zhang S, Liao R
Developmental neurobiology 2025 Oct;85(4):e22997
Developmental neurobiology 2025 Oct;85(4):e22997
Microglia in the Rostral Ventromedial Medulla Mediate Synaptic Pruning via the C1q/C3-CR3 Signaling Pathway-A Mechanism for the Chronic Orofacial Pain.
Huang X, Zeng J, Hu Z, Wu Y, Zhang G, Zhang C, Yu C, Song M
Molecular neurobiology 2025 Oct;62(10):13338-13351
Molecular neurobiology 2025 Oct;62(10):13338-13351
Deletion of ZNRF2 Exacerbates MPTP-Induced Parkinson's Disease by Activating mTOR-Mediated Neuroinflammatory Pathways.
Zhang F, Xu J, Yuan Q, Xie Y, Zhang L, Zhang J, Xu Z, Liu M
Molecular neurobiology 2025 Oct;62(10):12394-12412
Molecular neurobiology 2025 Oct;62(10):12394-12412
Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway.
Li Q, Hong H, Xu G, Xia M, Wang T, Zhou Z, Huang J, Fu Q, Cui Z
Journal of integrative neuroscience 2025 Oct 29;24(10):43900
Journal of integrative neuroscience 2025 Oct 29;24(10):43900
Modeling Alzheimer's Disease with APOE4 Neuron-Glial Brain Assembloids Reveals IGFBPs as Therapeutic Targets.
Sherman E, Qiu K, Roberts R, Shichman L, Li S, Sun H, Ide L, Tucker A, Lee S, Gniadzik W, Shin JB, Sol-Church K, Kapur J, Zhang A, Erisir A, Jiang L, Alzheimer’s Disease Neuroimaging Initiative
bioRxiv : the preprint server for biology 2025 Oct 19;
bioRxiv : the preprint server for biology 2025 Oct 19;
Ramelteon Ameliorates Isoflurane-Induced Hyperactivity and Social-Recognition Impairment in Aged Mice.
Takeda E, Abe M, Murakami R, Seki K
Journal of integrative neuroscience 2025 Oct 15;24(10):42403
Journal of integrative neuroscience 2025 Oct 15;24(10):42403
TDP-43 mediated oxidative stress induced mitochondrial dysfunction in neurons and hyperalgesia in sciatic nerve injured mice.
Li L, Huang P, Zhu D, Chen Y, Li Y, Weng B, Bai X, Cui J
Brain research 2025 Oct 15;1865:149883
Brain research 2025 Oct 15;1865:149883
Disulfide-Appended siRNA Nanoeyedrops: Noninvasive Gene Therapy for Targeting Retinal Angiogenesis.
Liu S, Wang D, Ye S, Zhang J, Du B, Lian Z, Yang W, Zhou J, Chen Q, Li J, Li J, Yang H
ACS nano 2025 Oct 14;19(40):35333-35347
ACS nano 2025 Oct 14;19(40):35333-35347
CircFGFR2 induces astrocyte pyroptosis to promote ischemic stroke.
Pang N, Liu Y, Yu S, Li Y, Shi K
Neuroscience 2025 Oct 1;584:356-366
Neuroscience 2025 Oct 1;584:356-366
Neuronutritional enhancement of antioxidant defense system through Nrf2/HO1/NQO1 axis in fibromyalgia.
Inferrera F, Tranchida N, Fusco R, Cuzzocrea S, Impellizzeri D, Siracusa R, D'Amico R, Rashan L, Badaeva A, Danilov A, Calabrese V, Di Paola R, Cordaro M
Neurochemistry international 2025 Nov;190:106057
Neurochemistry international 2025 Nov;190:106057
Microglial activation drives neuronal dysregulation in alcohol-induced seizure susceptibility.
Zhang S, Zhou Y, Ren Y, Shang J, Jiang A, Hong Y, Hong S, Wang C, Wang W, Chen J
Scientific reports 2025 Nov 3;15(1):38389
Scientific reports 2025 Nov 3;15(1):38389
Kaempferol attenuated LPS-induced microglial neurotoxicity by promoting mitophagy to inhibit mtDNA-mediated NLRP3 inflammasome activation.
Xiao L, Liang L, Zhou S, Peng F, Yuan C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157486
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157486
Urolithin B promotes the functional recovery of spinal cord injury by alleviating neuroinflammation via the inhibition of NLRP3 signaling pathway.
Su Y, Wang H, Yang W, Zhang S, Liu F, Han K, Guan F, Ma S, Cui Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157331
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157331
Trofinetide Improves Cognitive Function in APP/PS1 Mice by Suppressing Inflammation and Apoptosis.
Chen M, Ning Y, Yang H, Jia J
Molecular neurobiology 2025 Nov 21;63(1):129
Molecular neurobiology 2025 Nov 21;63(1):129
Xiaoyao San against depression via glia-mediated neuroinflammation using network pharmacology and experimental validation.
Liu XY, Yan YZ, Jiang AJ, He WY, Fang YY, Li CH, Deng MF, Tan SJ, Zeng P
Scientific reports 2025 Nov 12;15(1):39708
Scientific reports 2025 Nov 12;15(1):39708
Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.
Li H, Tao D, Chen Y, Deng Y, Wei W, Xue X
European journal of medical research 2025 Nov 10;30(1):1096
European journal of medical research 2025 Nov 10;30(1):1096
GIV/Girdin Modulation of Microglial Activation in Ischemic Stroke: Impact of FTO-Mediated m6A Modification.
Xie P, Xia M, Long T, Guo D, Cao W, Sun P, Yu W
Molecular neurobiology 2025 May;62(5):5501-5517
Molecular neurobiology 2025 May;62(5):5501-5517
Berbamine alleviates neuropathic pain via suppressing spinal TMEM34/SGK1/FOXO3 axis.
Yao CH, Zhang ZM, Zhang S, Jiang H, Wang R, Liu JH, Xie H, Dai WL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156619
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156619
Mg(2+)-Loaded Black Phosphorus Nanosheet Protects against Cerebral Ischemic Injury through Anti-Oxidative and Anti-Inflammatory Effects.
Wang M, Xia X, Li Y, Zhang K, Cheng X, Wen X, Zhao L, Guo X, Song F, Cheng A
Advanced healthcare materials 2025 May;14(13):e2500929
Advanced healthcare materials 2025 May;14(13):e2500929
Ectoparasites enhance survival by suppressing host exploration and limiting dispersal.
Liu P, Ren D, Li G, Xu X, Presotto L, Liu W, Zhao N, Li D, Chen M, Wang J, Liu X, Zhao C, Lu L, Liu Q
Nature communications 2025 May 9;16(1):4318
Nature communications 2025 May 9;16(1):4318
Neutrophil Extracellular Traps Promote AIM2-Dependent Microglial Pyroptosis Following Stroke.
Chen H, Ni L, Zhang J, Zheng X, Chen Y, Jin X, Hu B, Xu X, Tang Q, Li S, Hao Y, Sun S, He C, Cao S, Hu X
Aging and disease 2025 May 30;17(3):1616-1633
Aging and disease 2025 May 30;17(3):1616-1633
Clonidine Ameliorates Neuroinflammation in the Rat Model of Tourette Syndrome.
Ke Z, Huang Y, Wang A, Chen Y
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 May 20;20(1):56
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 May 20;20(1):56
DANCR knockdown alleviates neuroinflammation and functional recovery after spinal cord injury via regulating the ACTN4 / STAT3 axis.
Xia B, Yu C, Liu J, Lin J, Lyu J, Wang X, Zhu L
Archives of biochemistry and biophysics 2025 Mar;765:110293
Archives of biochemistry and biophysics 2025 Mar;765:110293
Exploring the active components and potential mechanisms of Zhimu-Huangbai herb-pair in the treatment of depression.
Lei X, Zhao D, Chen T, Li Q, Xue A, Hu Z, Jia F, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156365
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156365
Inhibiting HMGB1/AGER/NF-κB pathway prevents pro-inflammatory microglia polarization and protect photoreceptors in retinitis pigmentosa.
Hu C, Cui T, Xu Z, Yang K, Wu Y, Cai W, Yu J, Qiu Y
International immunopharmacology 2025 Mar 6;149:114192
International immunopharmacology 2025 Mar 6;149:114192
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Hao Z, Ji R, Su Y, Wang H, Yang W, Zhang S, Liu Y, Ma S, Guan F, Cui Y
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Transcranial magneto-acoustic stimulation enhances motor function and modulates cortical excitability of motor cortex in a Parkinson's disease mouse model.
Zhang S, Wang Q, Xu Y, Zhang H, Mi J, Lu X, Fan R, Lv J, Xu G
Behavioural brain research 2025 Mar 5;480:115364
Behavioural brain research 2025 Mar 5;480:115364
Sinomenine alleviates neuroinflammation in chronic cerebral hypoperfusion by promoting M2 microglial polarization and inhibiting neuronal pyroptosis via exosomal miRNA-223-3p.
Yang Q, Chen Q, Zhang KB, Liu Y, Zheng JC, Hu DX, Luo J
Acta neuropathologica communications 2025 Mar 5;13(1):48
Acta neuropathologica communications 2025 Mar 5;13(1):48
Multiple synergistic anti-aging effects of vascular cell adhesion molecule 1 functionalized nanoplatform to improve age-related neurodegenerative diseases.
Zhu S, Zhang Y, Li C, Deng Z, Yin Y, Dong Z, Kuang L, Li C, Hu X, Yin T, Wang Y
Journal of controlled release : official journal of the Controlled Release Society 2025 Mar 10;379:363-376
Journal of controlled release : official journal of the Controlled Release Society 2025 Mar 10;379:363-376
Nanoemulsion-based pseudopolyrotaxane hydrogel for enhanced corneal bioavailability and treatment of corneal inflammation.
Fang G, Zhao R, Zhu L, Wang Q, Peng S, Kang L, Lu H, Zhang G, Tang B
Journal of controlled release : official journal of the Controlled Release Society 2025 Mar 10;379:14-29
Journal of controlled release : official journal of the Controlled Release Society 2025 Mar 10;379:14-29
Allograft inflammatory Factor-1 induces the dedifferentiation of Vascular Smooth Muscle cells into a macrophage-like phenotype both in vivo and in vitro.
Dong R, Li J, Jiang G, Tian Y, Bi W
Experimental cell research 2025 Mar 1;446(1):114475
Experimental cell research 2025 Mar 1;446(1):114475
Electromagnetic pulse exposure induces neuroinflammation and blood-brain barrier disruption by activating the NLRP3 inflammasome/NF-κB signaling pathway in mice.
Lin Y, Lang H, Gao P, Miao X, Guo Q, Hao Y, Ai T, Li J, Zhang J, Guo G
Ecotoxicology and environmental safety 2025 Mar 1;292:117972
Ecotoxicology and environmental safety 2025 Mar 1;292:117972
Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model.
Ding X, Chen C, Zhao H, Dai B, Ye L, Song T, Huang S, Wang J, You T
Neural regeneration research 2025 Mar 1;20(3):858-872
Neural regeneration research 2025 Mar 1;20(3):858-872
Juvenile fluoxetine treatment affects the maturation of the medial prefrontal cortex and behavior of adolescent female rats.
Kryst J, Chocyk A, Solarz-Andrzejewska A, Majcher-Maślanka I
Pharmacological reports : PR 2025 Jun;77(3):670-688
Pharmacological reports : PR 2025 Jun;77(3):670-688
Myelination Trajectory and Microglial Dynamics Following Repeated Sevoflurane Exposure in Developing Brain.
Che J, Wu Y, Dong J, Jiang X, Yang L, Chen Y, Zhang J
Glia 2025 Jun;73(6):1221-1240
Glia 2025 Jun;73(6):1221-1240
Chaperone-mediated autophagy, heat shock protein 70, and serotonin: novel targets of beta-hydroxybutyrate in HFFD/LPS-induced sporadic Alzheimer's disease model.
Mohamed RA, Abdallah DM, El-Abhar HS
Inflammopharmacology 2025 Jun;33(6):3461-3477
Inflammopharmacology 2025 Jun;33(6):3461-3477
Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4.
Liu W, Zhu Y, Ye W, Xiong J, Wang H, Gao Y, Huang S, Zhang Y, Zhou X, Zhou X, Ge X, Cai W, Zheng X
Cell death and differentiation 2025 Jun;32(6):1041-1057
Cell death and differentiation 2025 Jun;32(6):1041-1057
Allopregnanolone relieves paclitaxel induced mechanical hypersensitivity via inhibiting spinal cord PGE(2)-EP2 mediated microglia-neuron signaling.
Guo K, Gao L, Li P, Feng S, Zhao L, Wang X
IBRO neuroscience reports 2025 Jun;18:211-221
IBRO neuroscience reports 2025 Jun;18:211-221
CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1-Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis.
Han J, Hong R, Cao C, Feng W, Zhuang W, Wang G, Tang J, Yang Y, Zhang C, Zhou A, Qu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414550
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414550
Dragon's Blood Modulates Disulfidptosis-Related Genes to Alleviate Ischemic Brain Injury in Mice.
Xu C, Hang H, Li W, Meng Y, Zhao H, Liu C, Zhang R
Neurochemical research 2025 Jun 6;50(3):185
Neurochemical research 2025 Jun 6;50(3):185
miR-210 Regulates Autophagy Through the AMPK/mTOR Signaling Pathway, Reduces Neuronal Cell Death and Inflammatory Responses, and Enhances Functional Recovery Following Cerebral Hemorrhage in Mice.
Wang Y, Jiang L, Tian JJ, Zhu LL, Dai HJ, Guo C, Zhou LY, Wang L, Lu Y, Zhang Y
Neurochemical research 2025 Jun 5;50(3):180
Neurochemical research 2025 Jun 5;50(3):180
Visualization of P2X7 Receptors in Living Human Gliomas: An 18F-GSK1482160 PET Imaging and Neuropathology Study.
Zhou W, Yue Q, Yuan Y, Huang Q, He K, Hua T, Han J, He Y, Guan Y, Chen L, Xie F, Mao Y
Clinical cancer research : an official journal of the American Association for Cancer Research 2025 Jun 3;31(11):2183-2195
Clinical cancer research : an official journal of the American Association for Cancer Research 2025 Jun 3;31(11):2183-2195
Qinglongyi nanoparticles alleviate neuroinflammation and promote neuronal survival by inhibiting neuronal ferroptosis in intracerebral hemorrhage.
Yan T, Kang G, Meng Y, Zhang L, Jiang Q, Shen N, Li H, Xu M, Yu L, Ni G, Ma H, Guo F, Cui Y, Che F
International immunopharmacology 2025 Jun 26;159:114945
International immunopharmacology 2025 Jun 26;159:114945
miR-29a nanoparticles improve chronic insomnia by regulating microglia activation and hippocampal neuronal cell pyroptosis through PER2/NF-κB axis.
Hou D, Hu Y, Li H, Yang G
International immunopharmacology 2025 Jun 26;159:114882
International immunopharmacology 2025 Jun 26;159:114882
Senolytic Treatment Attenuates Global Ischemic Brain Injury and Enhances Cognitive Recovery by Targeting Mitochondria.
Gu C, Guo T, Chen X, Zhou X, Sun Y
Cellular and molecular neurobiology 2025 Jun 18;45(1):60
Cellular and molecular neurobiology 2025 Jun 18;45(1):60
Targeting glial fibrillary acidic protein in glaucoma: a monoclonal antibody approach to modulate glial reactivity and neuroinflammation for neuroprotection.
Guan C, Zhang L, Fomo KN, Yang J, Pfeiffer N, Grus FH
Journal of neuroinflammation 2025 Jun 17;22(1):159
Journal of neuroinflammation 2025 Jun 17;22(1):159
GLUT1 maintains esophageal cancer stem cell-like characteristics by inhibiting autophagy-dependent ferroptosis via EGFR.
Sui X, Zhou H, Wang T
Experimental cell research 2025 Jun 15;449(2):114600
Experimental cell research 2025 Jun 15;449(2):114600
Anticonvulsant effect of Stachydrine on pentylenetetrazole-induced kindling seizure mouse model via Notch and NMDAR signaling pathways.
Li Q, Li R, Ge B, Luo X, Xu J, Fu L, Kong Y, Yang JY, Li S
Journal of ethnopharmacology 2025 Jun 12;349:119975
Journal of ethnopharmacology 2025 Jun 12;349:119975
Human brain cell types shape host-rabies virus transcriptional interactions revealing a preexisting pro-viral astrocyte subpopulation.
Feige L, Young K, Cerapio JP, Kozaki T, Kergoat L, Libri V, Ginhoux F, Hasan M, Ben Ameur L, Chin G, Goode Z, Bourhy H, Saunders A
bioRxiv : the preprint server for biology 2025 Jun 12;
bioRxiv : the preprint server for biology 2025 Jun 12;
Mesenchymal Stem Cell-Derived Mitochondrial Transfer Promotes Tip Cell Phenotype via Glutathione Metabolic Reprogramming in Stroke Mice.
Zhang Q, Huang J, Chen X, Li L, Chen L, Zhou X, Zhao X, Liu M, Zhao W, Yan J, Wang Y, Su Y, Liu Y, Xu S, Zeng W
ACS nano 2025 Jun 10;19(22):20452-20471
ACS nano 2025 Jun 10;19(22):20452-20471
Cyclophilin D knockdown/knockout promotes microglia M2 polarization by inhibiting STAT1 to alleviate neuroinflammation in neonatal white matter injury.
Zhou J, Gao T, Tang W, Wang Z, Zhao L, Wang L
Brain research 2025 Jun 1;1856:149596
Brain research 2025 Jun 1;1856:149596
Targeting PD-L1 for Ischemic Stroke Recovery: Age-Dependent Modulation of Immune and BBB Pathways.
Hang H, Xu C, Wang L, Liu C, Zhang R, Wu G, Zhao H
CNS neuroscience & therapeutics 2025 Jul;31(7):e70523
CNS neuroscience & therapeutics 2025 Jul;31(7):e70523
Incorporation of graphene oxide into collagenous biomaterials attenuates scar-forming phenotype transition of reactive astrocytes in vitro.
Verstappen K, Klymov A, Marques PAAP, Leeuwenburgh SCG, Walboomers XF
Brain research bulletin 2025 Jul;227:111380
Brain research bulletin 2025 Jul;227:111380
Developmental wave of programmed ganglion cell death in human retinal organoids.
Brooks T, Park YK, Vielle A, Ha M, Del Rio-Tsonis K, Robinson ML, Vergara MN
bioRxiv : the preprint server for biology 2025 Jul 30;
bioRxiv : the preprint server for biology 2025 Jul 30;
Candesartan Mitigates Perioperative Neurocognitive Disorders by Modulating Hypertension-Linked Neuroinflammatory Factor.
Wu Z, Li Y, Gong T, Li J, Zhao P, Huo X, Zhu Y, Zeng Q
Neurochemical research 2025 Jul 29;50(4):252
Neurochemical research 2025 Jul 29;50(4):252
The expression profile of type 1 equilibrative nucleoside transporter in aged C57BL/6J mouse brain.
Zhang XY, Ma Z, Jin YH, Long Z, Tang Q, He G, Jia YF
Acta biochimica et biophysica Sinica 2025 Jul 28;58(4):780-91
Acta biochimica et biophysica Sinica 2025 Jul 28;58(4):780-91
Cannabidiol ameliorates seizures and neuronal damage in ferric chloride-induced posttraumatic epilepsy by targeting TRPV1 channel.
Ma L, Gao Y, Chen J, Hai D, Yu J, Tang S, Liu N, Liu Y
Journal of ethnopharmacology 2025 Jul 24;351:120072
Journal of ethnopharmacology 2025 Jul 24;351:120072
Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model.
Yao L, Jing R, Wang C, Wang Y, Li X, Wu X, Wang Y, Liu L, Mu L, Liu P, Hu Y
Journal of ethnopharmacology 2025 Jul 24;351:120011
Journal of ethnopharmacology 2025 Jul 24;351:120011
Mild subcortical stroke induces widespread astrogliosis independent of microglia and age.
Stackhouse TL, Marxmiller BD, Sullivan SJ, McConnell HL, Knittel LM, De La Torre R, Houser A, Zhang W, Woltjer RL, Mishra A
bioRxiv : the preprint server for biology 2025 Jul 23;
bioRxiv : the preprint server for biology 2025 Jul 23;
Botulinum toxin type A inhibits microglia pyroptosis by suppressing Cblb-mediated degradation of Pdlim1 to attenuate neuropathic pain.
Tian S, Wu L, Zheng H, Cheng Z, Liu J, Liu M, Yu X, Tu J, Wu W
The journal of headache and pain 2025 Jul 22;26(1):165
The journal of headache and pain 2025 Jul 22;26(1):165
Kaempferol ameliorated central nervous injury induced by alcohol uptake through improving intestinal barrier function.
Zhou S, Liang L, Zhong W, Chen J, Xiao L
Neuroreport 2025 Jul 2;36(10):524-531
Neuroreport 2025 Jul 2;36(10):524-531
Effects of ATF2/TSC1 on epilepsy by modulating the microphages polarization of microglia.
Huang W, Chen W, Zhao Z, Liu L, Zhao Y, Chen X, Li R
Scientific reports 2025 Jul 2;15(1):22958
Scientific reports 2025 Jul 2;15(1):22958
Poldip2 Aggravates inflammation in diabetic retinopathy by impairing mitophagy via the AMPK/ULK1/Pink1 pathway.
Lin S, Ji Z, Gao J, Fan J, Hou J, Liu S, Wang C, Chen K, Tao L, Jiang Z
Life sciences 2025 Jul 15;373:123681
Life sciences 2025 Jul 15;373:123681
Integrative analysis identifies IL-6/JUN/MMP-9 pathway destroyed blood-brain-barrier in autism mice via machine learning and bioinformatic analysis.
Hu C, Li H, Cui J, Li Y, Zhang F, Li H, Luo X, Hao Y
Translational psychiatry 2025 Jul 11;15(1):239
Translational psychiatry 2025 Jul 11;15(1):239
Targeting modulation of the choroid plexus blood-CSF barrier and CSF hypersecretion via lipid nanoparticle-mediated co-delivery of siRNA and resveratrol.
Wang Q, Xia X, Zhang H, Li Y, Zhu L, Shi Y, Tang Y, Cheng J, Hui X, Gao H
Nature communications 2025 Jul 10;16(1):6389
Nature communications 2025 Jul 10;16(1):6389
SETD1B promotes brain cell ferroptosis in ischemic stroke mice via increasing H3K4me3 enrichment on the Tfrc promoter.
Wang L, Liu HR, Liu HQ, Li XS, Tang TT, Wang KJ, Wei GR, Tian J, Zhang YY, Luo XJ
Life sciences 2025 Jul 1;372:123625
Life sciences 2025 Jul 1;372:123625
THSG counteracts microglial glycolytic reprogramming and neuronal necroptosis both in vivo and in vitro under conditions of neuroinflammation.
Guo Z, Zhong S, Bai J, Lang X, Cao M, Hu Y, Qin X, Sun Y
Scientific reports 2025 Jul 1;15(1):21721
Scientific reports 2025 Jul 1;15(1):21721
Magnolol acts as a neurorestorative agent in an A(β1‑42)‑induced mouse model of Alzheimer's disease.
Yu Q, Shi Y, Wu Y, Liu R, Zhang H, Wu L, Ding M
Experimental and therapeutic medicine 2025 Jan;29(1):12
Experimental and therapeutic medicine 2025 Jan;29(1):12
Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage.
Li J, Hao G, Yan Y, Li M, Li G, Lu Z, Sun Z, Chen Y, Liu H, Zhao Y, Wu M, Bao X, Wang Y, Li Y
Neurochemistry international 2025 Jan;182:105914
Neurochemistry international 2025 Jan;182:105914
Remifentanil-induced inflammation in microglial cells: Activation of the PAK4-mediated NF-κB/NLRP3 pathway and onset of hyperalgesia.
Cui C, Wu X, Dong S, Chen B, Zhang T
Brain, behavior, and immunity 2025 Jan;123:334-352
Brain, behavior, and immunity 2025 Jan;123:334-352
Maternal separation during lactation affects recognition memory, emotional behaviors, hippocampus and gut microbiota composition in C57BL6J adolescent female mice.
Wu Z, Zhou L, Fu H, Xie Y, Sun L, Li Y, Xiao L, Zhang L, Su Y, Wang G
Behavioural brain research 2025 Jan 5;476:115249
Behavioural brain research 2025 Jan 5;476:115249
The aqueous extract of Armadillidium vulgare Latreille alleviates neuropathic pain via inhibiting neuron-astrocyte crosstalk mediated by the IL-12-IFN-γ-IFNGR-CXCL10 pathway.
Yang Y, Zhang S, Yang J, Yao C, Li X, Dai W, Liu J
Journal of ethnopharmacology 2025 Jan 31;340:119173
Journal of ethnopharmacology 2025 Jan 31;340:119173
Taxus chinensis (Pilg.) Rehder fruit attenuates aging behaviors and neuroinflammation by inhibiting microglia activation via TLR4/NF-κB/NLRP3 pathway.
Meimei C, Fei Z, Wen X, Huangwei L, Zhenqiang H, Rongjun Y, Qiang Z, Qiuyang L, Xiaozhen L, Yuan Y, Zhaoyang Y, Candong L
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118943
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118943
STEAP3-SLC39A8-mediated microglia ferroptosis involved in neurotoxicity in rats after exposure to lead and cadmium combined.
Sun Y, Liu J, Xiao K, Chen S, Ma J, Cao M, Yang Y, Shao H, Cui G, Du Z
International immunopharmacology 2025 Jan 27;146:113854
International immunopharmacology 2025 Jan 27;146:113854
Altered ATP13A2/PARK9 Levels Influence α-Synuclein Accumulation in Neurons via Phagocytosis and Secretion in Glial Cells.
Tsunemi T, Ishiguro Y, Yoroisaka A, Feng D, Hattori N
Cells 2025 Jan 22;14(3)
Cells 2025 Jan 22;14(3)
Semen Strychni Pulveratum and vomicine alleviate neuroinflammation in amyotrophic lateral sclerosis through cGAS-STING-TBK1 pathway.
Zhan Y, Huang J, Tang X, Du B, Yang B
Journal of ethnopharmacology 2025 Jan 10;336:118741
Journal of ethnopharmacology 2025 Jan 10;336:118741
Microglial activation and hypothalamic structural plasticity in HFD obesity: insights from semaglutide and minocycline.
Rong X, Wei F, Jiang Y, Ma Q, Wang D, Shen J
Journal of lipid research 2025 Feb;66(2):100736
Journal of lipid research 2025 Feb;66(2):100736
Evaluation of TRPM2 Channel-Mediated Autophagic Signaling Pathway in Hippocampus and Cortex Tissues of Rat Offspring Following Prenatal Exposure to Elevated Alcohol Levels.
Uğuz AC, Okan A, Doğanyiğit Z, Yilmaz S, Ateş Ş, Arikan Söylemez ES, Karabulut S, Kumru AS, Espino J
Environmental toxicology 2025 Feb;40(2):222-244
Environmental toxicology 2025 Feb;40(2):222-244
Microglia-derived Galectin-9 drives amyloid-β pathology in Alzheimer's disease.
Zhang G, Peng Q, Guo X, Pan L, Xiong M, Zhang X, Dai L, Zhang Z, Xiao T, He J, Liu M, Ke W, Zhang Z
Aging cell 2025 Feb;24(2):e14396
Aging cell 2025 Feb;24(2):e14396
Inhibition of Kv1.1 channels ameliorates Cu(II)-induced microglial activation and cognitive impairment in mice.
Ni W, Ding J, Gong P, Tan X, Li J
Neurochemistry international 2025 Feb;183:105936
Neurochemistry international 2025 Feb;183:105936
Demyelination of the amygdala mediates psychological stress-induced emotional disorders partially contributed by activation of P2X7R/NLRP3 cascade.
Li Y, Zhang Y, Lin D, Fu X, Jing C
Brain, behavior, and immunity 2025 Feb;124:365-375
Brain, behavior, and immunity 2025 Feb;124:365-375
OTUD5 Protects Dopaminergic Neurons by Promoting the Degradation of α-Synuclein in Parkinson's Disease Model.
Song X, Liu T, Yu L, Ji Q, Guo X, Zong R, Li Y, Huang G, Xue Q, Fu Q, Liu B, Zheng Y, Chen L, Gao C, Liu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2406700
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2406700
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.
He X, Deng B, Zhang C, Zhang G, Yang F, Zhu D, Yang Y, Ma B, Hu X, Wang Y, Kang X
Molecular medicine (Cambridge, Mass.) 2025 Feb 9;31(1):53
Molecular medicine (Cambridge, Mass.) 2025 Feb 9;31(1):53
Identification and Therapeutic Potential of Polymethoxylated Flavones in Citri Reticulatae Pericarpium for Alzheimer's Disease: Targeting Neuroinflammation.
Wang X, Yi Z, Zhang Y, Zhang J, Li X, Qi D, Wang Q, Chai X, Liu H, Wang G, Pan Y, Liu Y, Yu G
Molecules (Basel, Switzerland) 2025 Feb 7;30(4)
Molecules (Basel, Switzerland) 2025 Feb 7;30(4)
Schisandra chinensis lignans exerts endocannabinoids-like antidepressive effect: The phagocytotic relationship of activated CB2R-mediated M2 microglia and "stressed-but-viable" neuron.
Wang J, Du H, Li M, Yan T, Jia Y
Journal of ethnopharmacology 2025 Feb 27;342:119385
Journal of ethnopharmacology 2025 Feb 27;342:119385
Baicalein alleviates long-term cognitive impairments induced by repeated neonatal sevoflurane exposure via inhibition of cortical microglial TLR4/NF-kB signaling.
Niu Y, Zeng Q, Yang Y, Liu W, Zhang H, Chen S, Li X
Brain, behavior, & immunity - health 2025 Dec;50:101126
Brain, behavior, & immunity - health 2025 Dec;50:101126
Integrative single-cell and spatial transcriptome analysis reveals the functions of TREM2(high) macrophages and infarct border dynamics post-myocardial infarction.
Xiong T, Chen Y, Liu C, Li Y, Zhang Y, Chang Q
Molecular and cellular biochemistry 2025 Dec;480(12):6077-6109
Molecular and cellular biochemistry 2025 Dec;480(12):6077-6109
MicroRNA-3473b regulates corticosterone-induced microglial polarization and inflammation through TREM2.
Shi J, Ma C, Liu Y, Yang C, Wu J, Wang X
Journal of pharmacological sciences 2025 Dec;159(4):209-218
Journal of pharmacological sciences 2025 Dec;159(4):209-218
Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells-Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation.
Li J, Xu M, Cai B, Li X, Liang Z, Xia X, Zhang H, Zhang Z, Tan F, Zheng JC
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e08574
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e08574
VSIG2 as a novel immunosuppressive ligand interacts with Nectin-2 to regulate T cell responses.
Wang X, Hu R, Chen K, He K, Li Y, Gao J, Tian Y, Du G, Wang Z, Zhao Y, Lai L, Su M
Journal of neuroinflammation 2025 Dec 5;23(1):11
Journal of neuroinflammation 2025 Dec 5;23(1):11
Yueju pill and its active component- Myricetin attenuate the reinstatement of methamphetamine-seeking behavior in mice.
Du Y, Fan S, Yang X, Ma W, Li S, Xu Y, Li C, Chen S, Wang Y, Wang M, Ma T, Zhang J
International immunopharmacology 2025 Dec 3;166:115601
International immunopharmacology 2025 Dec 3;166:115601
Ectomesenchymal Stem Cell Transplantation Induces Microglial Polarization and Anti-inflammatory IL-10 Secretion via NF-κB and MAPK Pathways to Mitigate Brain Injury Post-cerebral Hemorrhage.
Li Y, Yang W, Tang Y, Du S, Ye Y, Xu B, Shi W, Zhao X, Lu X
Neurochemical research 2025 Dec 20;51(1):20
Neurochemical research 2025 Dec 20;51(1):20
Galectin-9 activates microglial asparagine endopeptidase and promotes α-synuclein pathology in Parkinson's disease.
Peng Q, Zhang G, Guo X, Xu X, Li Y, Pan L, Meng L, Xiong J, Li S, Zhang Z
Cell death and differentiation 2025 Dec 14;
Cell death and differentiation 2025 Dec 14;
The SARS-CoV-2 nucleocapsid protein induces microglia senescence-mediated cognitive impairment via Glycolysis.
Yang NS, Sha HX, Zhang CY, Chen H, Liu YB, Xiong JB, Duan JX, Zhang J, Guan CX, Zhou Y, Su F, Zhong WJ
Molecular medicine (Cambridge, Mass.) 2025 Dec 12;32(1):7
Molecular medicine (Cambridge, Mass.) 2025 Dec 12;32(1):7
SIRT1 Attenuates Neuropathic Pain via CDK5-Kalirin-7 Signaling Pathway in Type 2 Diabetic Rats.
Xie C, Cao Y, Shen Y, Wu S, Wang J, Ye X, Wei N, Cao H, Li J
Molecular neurobiology 2025 Aug;62(8):9670-9685
Molecular neurobiology 2025 Aug;62(8):9670-9685
More severe vascular remodeling in deep brain regions caused by hemodynamic differences is a potential mechanism of hypertensive cerebral small vessel disease.
Liu N, Li N, Cao X, Qin W, Huang Q, Xue Y, Zhang M, Zhang Y, Kang S, Chen G, Tang J, Wang S, Fu J
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2025 Aug;45(8):1593-1605
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2025 Aug;45(8):1593-1605
The slow progression of Japanese encephalitis in aged mice is likely associated to B cell recruitment in the brain.
Song ZR, Yang YL, Zhou Y, Liu LB, Xue FY, Liu LS, Gao N, Fan DY, Wang YS, An J, Wang PG
Virologica Sinica 2025 Aug;40(4):546-559
Virologica Sinica 2025 Aug;40(4):546-559
Mechanism of Dendrobium officinale polysaccharide in alleviating Alzheimer's disease: Insights from metabolomics, lipidomics, and proteomics analysis.
Fu J, Liang Z, Chen Z, Chen W, Zhou Y, Xiong F, Meng L, Liang Q, Gao H
International journal of biological macromolecules 2025 Aug;319(Pt 2):145531
International journal of biological macromolecules 2025 Aug;319(Pt 2):145531
Synergistic microglial modulation by laminarin-based platinum nanozymes for potential intracerebral hemorrhage therapy.
Guo X, Zheng Q, Gao W, Xiao Y, Shi L, Lin F, Xiong Y, Zhang Y, Xu Q, Wang L, He S, Zheng F
Biomaterials 2025 Aug;319:123212
Biomaterials 2025 Aug;319:123212
Oseltamivir Phosphate Modulates CD24-Siglec-G/10 Interaction to Suppress Microglial-Driven Neuroinflammation After Cardiac Arrest.
Chen Y, Liu Y, Li N, Wang L, Li P, Sun Z, Yu D, Tang Z, Gong P
CNS neuroscience & therapeutics 2025 Aug;31(8):e70495
CNS neuroscience & therapeutics 2025 Aug;31(8):e70495
Metformin promotes PEN2 expression to attenuate microglia-mediated neurotoxicity induced by HIV-1 Tat.
Shen Y, Xu T, Sun Y, Zhang K, Cao X, Shen L, Tang M
Journal of neurovirology 2025 Aug;31(4):376-388
Journal of neurovirology 2025 Aug;31(4):376-388
Mechanistic Study of Jaceosidin in Regulating Secondary Inflammation After Spinal Cord Injury in Mouse by Inhibiting PKM2 Activity.
Dai B, Fan Z, Chen R, Weng X, Fang R
Neuromolecular medicine 2025 Aug 6;27(1):57
Neuromolecular medicine 2025 Aug 6;27(1):57
The mechanism of Yizhi Qingxin formula to improve neuroinflammation in Alzheimer's disease by regulating the TLR4/NF‑κB/NLRP3 pathway.
Chen WX, Huang QY, Sun JH, Yang XY, Pei H, Cao Y, Li H, Ma LN
Journal of Asian natural products research 2025 Aug 4;:1-19
Journal of Asian natural products research 2025 Aug 4;:1-19
Cerebral blood flow in elastin haploinsufficient and 3xTg-AD mice.
Cullen AE, Reeve EH, Winder NR, Henson GD, Arora N, Leonhardt T, Hogan A, Kumaran SK, Setthavonsack N, Krajbich V, Alkayed NJ, Pike MM, Woltjer RL, Walker AE
bioRxiv : the preprint server for biology 2025 Aug 22;
bioRxiv : the preprint server for biology 2025 Aug 22;
Monocyte-Platelet Aggregates Are Major Source of BDNF after Bacterial Stimulation of Human Peripheral Blood Immune Cells.
Sarcletti F, Dijmarescu M, Eigenschink M, Wukowits N, Oehler B, Mayer T, Pell S, Tandecki A, Seki D, Spittler A, Berry D, Berger A, Wisgrill L
European journal of immunology 2025 Apr;55(4):e202451538
European journal of immunology 2025 Apr;55(4):e202451538
Salidroside improves blood-brain barrier integrity and cognitive function in hypobaric hypoxia mice by inhibiting microglia activation through GSK3β.
Zhang X, Zhang H, Liu Z, Huang T, Yi R, Ma Z, Gao Y
Phytotherapy research : PTR 2025 Apr;39(4):1808-1825
Phytotherapy research : PTR 2025 Apr;39(4):1808-1825
Recombinant human heavy-chain ferritin nanoparticles loaded with rosuvastatin attenuates secondary brain injury in intracerebral hemorrhage.
Guo T, Wang Y, Hayat MA, Si Y, Ni Y, Zhang J, Qiu Y, Zeng Y, Cao Y, Hong Y, Chen B, Hu J
International journal of biological macromolecules 2025 Apr;302:140542
International journal of biological macromolecules 2025 Apr;302:140542
Mitochondrial respiratory complex IV deficiency recapitulates amyotrophic lateral sclerosis.
Cheng M, Lu D, Li K, Wang Y, Tong X, Qi X, Yan C, Ji K, Wang J, Wang W, Lv H, Zhang X, Kong W, Zhang J, Ma J, Li K, Wang Y, Feng J, Wei P, Li Q, Shen C, Fu XD, Ma Y, Zhang X
Nature neuroscience 2025 Apr;28(4):748-756
Nature neuroscience 2025 Apr;28(4):748-756
Inhibition of hippocampal mossy fiber plasticity and episodic memory by human Aβ oligomers is prevented by enhancing cAMP signaling in Alzheimer's mice.
Jin SX, Bellier JP, Wells A, LIopis PM, Anekal PV, Tresback JS, Caldarone BJ, Liu L, Li S, Dettmer U, Ramalingam N, Selkoe DJ
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 Apr;21(4):e70194
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 Apr;21(4):e70194
Targeting ceramide-induced microglial pyroptosis: Icariin is a promising therapy for Alzheimer's disease.
Li H, Xiao Q, Zhu L, Kang J, Zhan Q, Peng W
Journal of pharmaceutical analysis 2025 Apr;15(4):101106
Journal of pharmaceutical analysis 2025 Apr;15(4):101106
Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia.
Li X, Jin S, Wang D, Wu Y, Tang X, Liu Y, Yao T, Han S, Sun L, Wang Y, Hou SX
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2414260
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2414260
Photobiomodulation modulates mitochondrial energy metabolism and ameliorates neurological damage in an APP/PS1 mousmodel of Alzheimer's disease.
Chen H, Li N, Liu N, Zhu H, Ma C, Ye Y, Shi X, Luo G, Dong X, Tan T, Wei X, Yin H
Alzheimer's research & therapy 2025 Apr 5;17(1):72
Alzheimer's research & therapy 2025 Apr 5;17(1):72
Green Tea Ameliorates Depression-Like Behavior and Cognitive Impairment Induced by High-Fat Diet and Chronic Mild Stress.
Fan M, Jiang Y, Cai C, Wang Z, Chen L, Hu S, Zhang X, Yin H, Qian Z, Huang S, Yang J
Phytotherapy research : PTR 2025 Apr 17;
Phytotherapy research : PTR 2025 Apr 17;
Luteolin attenuates cadmium neurotoxicity by suppressing glial inflammation and supporting neuronal survival.
Ma HY, Wang J, Wang J, Guo Z, Qin XY, Lan R, Hu Y
International immunopharmacology 2025 Apr 16;152:114406
International immunopharmacology 2025 Apr 16;152:114406
Akkermansia muciniphila protects against dopamine neurotoxicity by modulating butyrate to inhibit microglia-mediated neuroinflammation.
Xu K, Wang G, Gong J, Yang X, Cheng Y, Li D, Sheng S, Zhang F
International immunopharmacology 2025 Apr 16;152:114374
International immunopharmacology 2025 Apr 16;152:114374
Extracellular Vesicle-Liposome-Darunavir Formulation for the Treatment of HIV Neuropathogenesis.
Zhou L, Godse S, Sinha N, Ma D, Mirzahosseini G, Salman M, Pulliam P, Tan C, Singh UP, Ishrat T, Kochat H, Kumar S
ACS applied nano materials 2025 Apr 11;8(14):6857-6876
ACS applied nano materials 2025 Apr 11;8(14):6857-6876
Characterization of Chitinase 3-like protein 1 spatiotemporal distribution in human post-traumatic brain contusions and other neuropathological scenarios.
Carabias CS, Alves VC, Hernández Laín A, Lagares A
Journal of neuropathology and experimental neurology 2025 Apr 1;84(4):305-328
Journal of neuropathology and experimental neurology 2025 Apr 1;84(4):305-328
mtDNA-cGAS-STING axis-dependent NLRP3 inflammasome activation contributes to postoperative cognitive dysfunction induced by sevoflurane in mice.
Yang NS, Zhong WJ, Sha HX, Zhang CY, Jin L, Duan JX, Xiong JB, You ZJ, Zhou Y, Guan CX
International journal of biological sciences 2024;20(5):1927-1946
International journal of biological sciences 2024;20(5):1927-1946
(+)-Borneol inhibits neuroinflammation and M1 phenotype polarization of microglia in epileptogenesis through the TLR4-NFκB signaling pathway.
Li S, Adamu A, Ye Y, Gao F, Mi R, Xue G, Wang Z
Frontiers in neuroscience 2024;18:1497102
Frontiers in neuroscience 2024;18:1497102
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Drug design, development and therapy 2024;18:1349-1368
Drug design, development and therapy 2024;18:1349-1368
Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice.
Zou Y, Wang C, Li H, Zhong M, Lin J, Hu Y, Chen Z, Gan CL
Frontiers in pharmacology 2024;15:1500105
Frontiers in pharmacology 2024;15:1500105
Profiling hypoxia signaling reveals a lncRNA signature contributing to immunosuppression in high-grade glioma.
Li X, Xu J, Li X, Shi J, Wei C, Liang Q
Frontiers in immunology 2024;15:1471388
Frontiers in immunology 2024;15:1471388
Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease.
Wang YH, Chen X, Bai YZ, Gao P, Yang Z, Guo Q, Lu YY, Zheng J, Liu D, Yang J, Tu PF, Zeng KW
Theranostics 2024;14(3):988-1009
Theranostics 2024;14(3):988-1009
The CEBPB(+) glioblastoma subcluster specifically drives the formation of M2 tumor-associated macrophages to promote malignancy growth.
Yang Y, Jin X, Xie Y, Ning C, Ai Y, Wei H, Xu X, Ge X, Yi T, Huang Q, Yang X, Jiang T, Wang X, Piao Y, Jin X
Theranostics 2024;14(10):4107-4126
Theranostics 2024;14(10):4107-4126
HGFIN deficiency exacerbates spinal cord injury by promoting inflammation and cell apoptosis through regulation of the PI3K/AKT signaling pathway.
Ding Q, Gao H, Hu X, Gao W
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Sep;33(9):929-940
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Sep;33(9):929-940
Escitalopram moderately outperforms citalopram towards anti-neuroinflammation and neuroprotection in 6-hydroxydopamine-induced mouse model of Parkinson's disease.
Ovlyakulov B, Hu BL, Kan HY, Guo Q, Li XF, Fan HH, Wu HM, Wang JY, Zhang X, Zhu JH
International immunopharmacology 2024 Sep 30;139:112715
International immunopharmacology 2024 Sep 30;139:112715
Tyrosine phosphorylation and palmitoylation of TRPV2 ion channel tune microglial beta-amyloid peptide phagocytosis.
Yang S, Du Y, Li Y, Tang Q, Zhang Y, Zhao X
Journal of neuroinflammation 2024 Sep 3;21(1):218
Journal of neuroinflammation 2024 Sep 3;21(1):218
Regulation of leptin signaling and diet-induced obesity by SEL1L-HRD1 ER-associated degradation in POMC expressing neurons.
Mao H, Kim GH, Pan L, Qi L
Nature communications 2024 Sep 29;15(1):8435
Nature communications 2024 Sep 29;15(1):8435
β-chitosan attenuates hepatic macrophage-driven inflammation and reverses aging-related cognitive impairment.
Zou C, Cai R, Li Y, Xue Y, Zhang G, Alitongbieke G, Pan Y, Zhang S
iScience 2024 Sep 20;27(9):110766
iScience 2024 Sep 20;27(9):110766
Ginsenoside compound K alleviates D-galactose-induced mild cognitive impairment by modulating gut microbiota-mediated short-chain fatty acid metabolism.
Yan X, Bai X, Fu R, Duan Z, Zeng W, Zhu C
Food & function 2024 Sep 16;15(18):9037-9052
Food & function 2024 Sep 16;15(18):9037-9052
Stereotactically intracerebral transplantation of neural stem cells for ischemic stroke attenuated inflammatory responses and promoted neurogenesis: an experimental study with monkeys.
Liu YF, Liu HT, Chang C, Yang CX, Liu XN, Wang X, Ge W, Wang RZ, Bao XJ
International journal of surgery (London, England) 2024 Sep 1;110(9):5417-5433
International journal of surgery (London, England) 2024 Sep 1;110(9):5417-5433
Rhein inhibits M1 polarization of BV2 microglia through MAPK/IκB signalling pathway and reduces neurotoxicity caused by neuroinflammation.
Qin X, Li B, Hu B, Huang J, Tian X, Zhang X, Wang Y, Huang W
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2024 Oct;84(6):533-545
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2024 Oct;84(6):533-545
Targeting Mitochondrial Oxidative Stress to Protect Against Preterm Birth and Fetal Brain Injury via Nrf2 Induction.
Chen C, Zhu S, Fu T, Chen Y, Bai L, Chen D
Antioxidants & redox signaling 2024 Oct;41(10-12):597-615
Antioxidants & redox signaling 2024 Oct;41(10-12):597-615
ClassIIb histone deacetylase participates in perioperative neurocognitive disorders in elderly mice via HSP90/GR signaling pathway.
Liu Y, Wang X, Wang J, Jin Q, Cai W, Pan C, Nivar J, Tao Y, Cao H, Li J
Experimental neurology 2024 Oct;380:114922
Experimental neurology 2024 Oct;380:114922
ADSC-derived exosomes provide neuroprotection in sepsis-associated encephalopathy by regulating hippocampal pyroptosis.
Zhan Y, Zhang L, Sun J, Yao H, Chen J, Tian M
Experimental neurology 2024 Oct;380:114900
Experimental neurology 2024 Oct;380:114900
Choroid plexus CCL2‒CCR2 signaling orchestrates macrophage recruitment and cerebrospinal fluid hypersecretion in hydrocephalus.
Wang Q, Liu F, Li Y, Zhang H, Qi X, Wu K, Zhang Y, You S, Liu W, Hui X, Li H, Zhu L, Gao H, Cheng J
Acta pharmaceutica Sinica. B 2024 Oct;14(10):4544-4559
Acta pharmaceutica Sinica. B 2024 Oct;14(10):4544-4559
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice.
Zheng S, Zhu J, Wang C, Wu Y, Sun S, Guo H, Chang Y, Ma R, Li G
Cell communication and signaling : CCS 2024 Oct 24;22(1):516
Cell communication and signaling : CCS 2024 Oct 24;22(1):516
Extracellular vesicles from neural stem cells safeguard neurons in intracerebral hemorrhage by suppressing reactive astrocyte neurotoxicity.
Li T, Zhang L, Wang P, Yu J, Zhong J, Tang Q, Zhu T, Chen K, Li F, Hong P, Wei J, Sun X, Ji G, Song B, Zhu J
Cell reports 2024 Oct 22;43(10):114854
Cell reports 2024 Oct 22;43(10):114854
Electroacupuncture attenuates depressive-like behaviors in poststroke depression mice through promoting hippocampal neurogenesis and inhibiting TLR4/NF-κB/NLRP3 signaling pathway.
Li M, Yang F, Zhang X, Yang H, He X, Mao Z, Mao L
Neuroreport 2024 Oct 2;35(14):947-960
Neuroreport 2024 Oct 2;35(14):947-960
Remimazolam ameliorates postoperative cognitive dysfunction after deep hypothermic circulatory arrest through HMGB1-TLR4-NF-κB pathway.
Mao Q, Liang B, Leng Z, Ma W, Chen Y, Xie Y
Brain research bulletin 2024 Oct 15;217:111086
Brain research bulletin 2024 Oct 15;217:111086
Hic-5 antisense oligonucleotide inhibits advanced hepatic fibrosis and steatosis in vivo.
Noguchi M, Miyauchi A, Masaki Y, Sakaki M, Lei XF, Kobayashi-Tanabe M, Miyazaki A, Aoki T, Yoshida H, Seio K, Kim-Kaneyama JR
JHEP reports : innovation in hepatology 2024 Nov;6(11):101195
JHEP reports : innovation in hepatology 2024 Nov;6(11):101195
Single-cell transcriptomics reveals IRF7 regulation of the tumor microenvironment in isocitrate dehydrogenase wild-type glioma.
Li J, Long S, Yang Z, Wei W, Yu S, Liu Q, Hui X, Li X, Wang Y
MedComm 2024 Nov;5(11):e754
MedComm 2024 Nov;5(11):e754
Immune-mediated impairment of tonic immobility defensive behavior in an experimental model of colonic inflammation.
Menescal-de-Oliveira L, Brentegani MR, Teixeira FP, Giusti H, Saia RS
Pflugers Archiv : European journal of physiology 2024 Nov;476(11):1743-1760
Pflugers Archiv : European journal of physiology 2024 Nov;476(11):1743-1760
Aged bone marrow macrophages drive systemic aging and age-related dysfunction via extracellular vesicle-mediated induction of paracrine senescence.
Hou J, Chen KX, He C, Li XX, Huang M, Jiang YZ, Jiao YR, Xiao QN, He WZ, Liu L, Zou NY, Huang M, Wei J, Xiao Y, Yang M, Luo XH, Zeng C, Lei GH, Li CJ
Nature aging 2024 Nov;4(11):1562-1581
Nature aging 2024 Nov;4(11):1562-1581
IDO-Kynurenine pathway mediates NLRP3 inflammasome activation-induced postoperative cognitive impairment in aged mice.
Lu J, Zhang Y, Hao Q, Zhou H, Zong Y
The International journal of neuroscience 2024 Nov;134(11):1309-1319
The International journal of neuroscience 2024 Nov;134(11):1309-1319
Neuroprotective effects of mesenchymal stromal cells in mouse models of Alzheimer's Disease: The Mediating role of gut microbes and their metabolites via the Microbiome-Gut-Brain axis.
Xing C, Zhang X, Wang D, Chen H, Gao X, Sun C, Guo W, Roshan S, Li Y, Hang Z, Cai S, Lei T, Bi W, Hou L, Li L, Wu Y, Li L, Zeng Z, Du H
Brain, behavior, and immunity 2024 Nov;122:510-526
Brain, behavior, and immunity 2024 Nov;122:510-526
Brain Resident Ly6C(hi) Monocytes Are Necessary for Maintaining Adult Hippocampal Neurogenesis.
Huang Y, Gao N, Liu B, Luo W, Chen J, Chen Y, Bi Y, Zhou Z
Aging and disease 2024 Nov 18;16(5):3069-3088
Aging and disease 2024 Nov 18;16(5):3069-3088
Acupuncture Ameliorates Depression-Like Behaviors Through Modulating the Neuroinflammation Mediated by TLR4 Signaling Pathway in Rats Exposed to Chronic Restraint Stress.
Jiang H, Long X, Wang Y, Zhang X, Chen L, Yang X, Zhao B, Zhang Y, Chai Y, Bao T
Molecular neurobiology 2024 May;61(5):2606-2619
Molecular neurobiology 2024 May;61(5):2606-2619
Tonic excitation by astrocytic GABA causes neuropathic pain by augmenting neuronal activity and glucose metabolism.
Ju YH, Cho J, Park JY, Kim H, Hong EB, Park KD, Lee CJ, Chung E, Kim HI, Nam MH
Experimental & molecular medicine 2024 May;56(5):1193-1205
Experimental & molecular medicine 2024 May;56(5):1193-1205
Glucose-modified BSA/procyanidin C1 NPs penetrate the blood-brain barrier and alleviate neuroinflammation in Alzheimer's disease models.
Duan L, Hao Z, Ji R, Li X, Wang H, Su Y, Guan F, Ma S
International journal of biological macromolecules 2024 May;268(Pt 1):131739
International journal of biological macromolecules 2024 May;268(Pt 1):131739
MG53/GMs/HA-Dex neural scaffold promotes the functional recovery of spinal cord injury by alleviating neuroinflammation.
Li X, Ji R, Duan L, Hao Z, Su Y, Wang H, Guan F, Ma S
International journal of biological macromolecules 2024 May;267(Pt 2):131520
International journal of biological macromolecules 2024 May;267(Pt 2):131520
Modulation of Cerebrospinal Fluid Dysregulation via a SPAK and OSR1 Targeted Framework Nucleic Acid in Hydrocephalus.
Wang Q, Cheng J, Liu F, Zhu J, Li Y, Zhao Y, Li X, Zhang H, Ju Y, Ma L, Hui X, Lin Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2306622
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2306622
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
Wang L, Li C, Zhan H, Li S, Zeng K, Xu C, Zou Y, Xie Y, Zhan Z, Yin S, Zeng Y, Chen X, Lv G, Han Z, Zhou D, Zhou D, Yang Y, Zhou A
Cell reports. Medicine 2024 May 21;5(5):101533
Cell reports. Medicine 2024 May 21;5(5):101533
CDDO, an Anti-Inflammatory and Antioxidant Compound, Attenuates Vasospasm and Neuronal Cell Apoptosis in Rats Subjected to Experimental Subarachnoid Hemorrhage.
Winardi W, Lo YP, Tsai HP, Huang YH, Tseng TT, Chung CL
Current issues in molecular biology 2024 May 13;46(5):4688-4700
Current issues in molecular biology 2024 May 13;46(5):4688-4700
Synergistic effect of mesenchymal stem cell-derived extracellular vesicle and miR-137 alleviates autism-like behaviors by modulating the NF-κB pathway.
Qin Q, Shan Z, Xing L, Jiang Y, Li M, Fan L, Zeng X, Ma X, Zheng D, Wang H, Wang H, Liu H, Liang S, Wu L, Liang S
Journal of translational medicine 2024 May 13;22(1):446
Journal of translational medicine 2024 May 13;22(1):446
MSC-derived exosomal miR-140-3p improves cognitive dysfunction in sepsis-associated encephalopathy by HMGB1 and S-lactoylglutathione metabolism.
Ma Y, She X, Liu Y, Qin X
Communications biology 2024 May 11;7(1):562
Communications biology 2024 May 11;7(1):562
RTA-408 Regulates p-NF-κB/TSLP/STAT5 Signaling to Ameliorate Nociceptive Hypersensitivity in Chronic Constriction Injury Rats.
Lu YY, Tsai HP, Tsai TH, Miao HC, Zhang ZH, Wu CH
Molecular neurobiology 2024 Mar;61(3):1714-1725
Molecular neurobiology 2024 Mar;61(3):1714-1725
Htr2b Promotes M1 Microglia Polarization and Neuroinflammation after Spinal Cord Injury via Inhibition of Neuregulin-1/ErbB Signaling.
Chen W, Gao X, Yang W, Xiao X, Pan X, Li H
Molecular neurobiology 2024 Mar;61(3):1643-1654
Molecular neurobiology 2024 Mar;61(3):1643-1654
Inhibiting the NLRP3 Inflammasome with MCC950 Alleviates Neurological Impairment in the Brain of EAE Mice.
Hou B, Yin J, Liu S, Guo J, Zhang B, Zhang Z, Yang L, Tan X, Long Y, Feng S, Zhou J, Wu Y, Wang X, Han S, Wang Z, He X
Molecular neurobiology 2024 Mar;61(3):1318-1330
Molecular neurobiology 2024 Mar;61(3):1318-1330
Near-infrared light-activatable, analgesic nanocomposite delivery system for comprehensive therapy of diabetic wounds in rats.
Chen S, Wang H, Du J, Ding Z, Wang T, Zhang L, Yang J, Guan Y, Chen C, Li M, Hei Z, Tao Y, Yao W
Biomaterials 2024 Mar;305:122467
Biomaterials 2024 Mar;305:122467
Intracerebral hemorrhage-induced brain injury in mice: The role of peroxiredoxin 2-Toll-like receptor 4 inflammatory axis.
Du Y, Wang J, Zhang J, Li N, Li G, Liu X, Lin Y, Wang D, Kang K, Bian L, Zhao X
CNS neuroscience & therapeutics 2024 Mar;30(3):e14681
CNS neuroscience & therapeutics 2024 Mar;30(3):e14681
Human umbilical cord mesenchymal stem cell-derived exosomes attenuate neuroinflammation and oxidative stress through the NRF2/NF-κB/NLRP3 pathway.
Che J, Wang H, Dong J, Wu Y, Zhang H, Fu L, Zhang J
CNS neuroscience & therapeutics 2024 Mar;30(3):e14454
CNS neuroscience & therapeutics 2024 Mar;30(3):e14454
Rasd1 is involved in white matter injury through neuron-oligodendrocyte communication after subarachnoid hemorrhage.
Fu W, Che X, Tan J, Cui S, Ma Y, Xu D, Long H, Yang X, Wen T, He Z
CNS neuroscience & therapeutics 2024 Mar;30(3):e14452
CNS neuroscience & therapeutics 2024 Mar;30(3):e14452
Novel perfluorocarbon-based oxygenation therapy alleviates Post-SAH hypoxic brain injury by inhibiting HIF-1α.
Peng Z, Ye QS, Li XJ, Zheng DY, Zhou Y, Hang CH, Wu JH, Li W, Zhuang Z
Free radical biology & medicine 2024 Mar;214:173-183
Free radical biology & medicine 2024 Mar;214:173-183
LncTCONS_00058568 is involved in the pathophysiologic processes mediated by P2X7R in the lower thoracic spinal cord after acute kidney injury.
Wang Y, Chen Z, Liu Q, Lv Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 31;38(6):e23563
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 31;38(6):e23563
Inhibition of repulsive guidance molecule-a ameliorates compromised blood-spinal cord barrier integrity associated with neuromyelitis optica in rats.
Katsu M, Sekine-Tanaka M, Tanaka M, Horai Y, Akatsuka A, Suga M, Kiyohara K, Fujita T, Sasaki A, Yamashita T
Journal of neuroimmunology 2024 Mar 15;388:578297
Journal of neuroimmunology 2024 Mar 15;388:578297
MyD88 Inhibition Attenuates Cerebral Ischemia-reperfusion Injury by Regulating the Inflammatory Response and Reducing Blood-brain Barrier Damage.
Jiang F, Xu C, Fan X, Yang S, Fan W, Li M, Song J, Wei W, Chen H, Zhong D, Li G
Neuroscience 2024 Jun 21;549:121-137
Neuroscience 2024 Jun 21;549:121-137
cGAS/STING signaling pathway-mediated microglial activation in the PFC underlies chronic ethanol exposure-induced anxiety-like behaviors in mice.
Zhao W, Zhao S, Wei R, Wang Z, Zhang F, Zong F, Zhang HT
International immunopharmacology 2024 Jun 15;134:112185
International immunopharmacology 2024 Jun 15;134:112185
A disulfiram derivative against lung cancer via the Notch signaling pathway without neurotoxicity and hepatotoxicity.
Lv H, Yang H, Duan Y, Sha H, Zhao Z
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4747-4760
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4747-4760
The impact of Nrf2 knockout on the neuroprotective effects of dexmedetomidine in a mice model of cognitive impairment.
Chen L, Yue Z, Liu Z, Liu H, Zhang J, Zhang F, Hu T, Fu J
Behavioural brain research 2024 Jul 9;469:115006
Behavioural brain research 2024 Jul 9;469:115006
Echinatin alleviates inflammation and pyroptosis in hypoxic-ischemic brain damage by inhibiting TLR4/ NF-κB pathway.
Tao X, Hu Y, Mao N, Shen M, Fang M, Zhang M, Lou J, Fang Y, Guo X, Lin Z
International immunopharmacology 2024 Jul 30;136:112372
International immunopharmacology 2024 Jul 30;136:112372
Trilobatin suppresses aging-induced cognitive impairment by targeting SIRT2: Involvement of remodeling gut microbiota to mediate the brain-gut axis.
Xie DY, Lin M, Luo YM, Dong L, Wei Y, Gao JM, Zhu YZ, Gong QH
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155744
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155744
Disorder of neuroplasticity aggravates cognitive impairment via neuroinflammation associated with intestinal flora dysbiosis in chronic heart failure.
Chen J, Wei X, Wu X, Zhang Q, Xia G, Xia H, Shang H, Lin S
Aging 2024 Jul 1;16(13):10882-10904
Aging 2024 Jul 1;16(13):10882-10904
Melatonin Exerts an Anti-Panoptoic Role in Spinal Cord Ischemia-Reperfusion Injured Rats.
Xie L, Wu H, Shi W, Zhang J, Huang X, Yu T
Advanced biology 2024 Jan;8(1):e2300424
Advanced biology 2024 Jan;8(1):e2300424
3-N-butylphthalide attenuates neuroinflammation in rotenone-induced Parkinson's disease models via the cGAS-STING pathway.
Liu Y, Duan R, Li P, Zhang B, Liu Y
International journal of immunopathology and pharmacology 2024 Jan-Dec;38:3946320241229041
International journal of immunopathology and pharmacology 2024 Jan-Dec;38:3946320241229041
BAFF deficiency aggravated optic nerve crush-induced retinal ganglion cells damage by regulating apoptosis and neuroinflammation via NF-κB-IκBα signaling.
Lin J, Deng W, Liao J, Ke D, Cui L, Zhong H, Huang K, Jiang L, Chen Q, Xu F, Tang F
International immunopharmacology 2024 Jan 5;126:111287
International immunopharmacology 2024 Jan 5;126:111287
Based on spinal central sensitization creating analgesic screening approach to excavate anti-neuropathic pain ingredients of Corydalis yanhusuo W.T.Wang.
Zhou MY, Yao CH, Yang YJ, Li X, Yang J, Liu JH, Yu BY, Dai WL
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117084
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117084
Extract of Astragali Radix and Solanum nigrum Linne regulates microglia and macrophage polarization and inhibits the growth and infiltration of C6 glioblastoma.
Shen M, Liu S, Wei Q, Zhang X, Wen S, Qiu R, Li Y, Fan H
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117067
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117067
SEL1L-HRD1 ER-associated degradation regulates leptin receptor maturation and signaling in POMC neurons in diet-induced obesity.
Mao H, Kim GH, Qi L
Research square 2024 Jan 12;
Research square 2024 Jan 12;
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway.
Lu T, Ding L, Zheng X, Li Y, Wei W, Liu W, Tao J, Xue X
Molecular neurobiology 2024 Feb;61(2):753-771
Molecular neurobiology 2024 Feb;61(2):753-771
The role of ApoE in fatty acid transport from neurons to astrocytes under ischemia/hypoxia conditions.
Chen H, Zhao S, Jian Q, Yan Y, Wang S, Zhang X, Ji Y
Molecular biology reports 2024 Feb 23;51(1):320
Molecular biology reports 2024 Feb 23;51(1):320
SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex.
Lin LL, Wang HH, Pederson B, Wei X, Torres M, Lu Y, Li ZJ, Liu X, Mao H, Wang H, Zhou LE, Zhao Z, Sun S, Qi L
Nature communications 2024 Feb 16;15(1):1440
Nature communications 2024 Feb 16;15(1):1440
Disease-Associated Neurotoxic Astrocyte Markers in Alzheimer Disease Based on Integrative Single-Nucleus RNA Sequencing.
Yu W, Li Y, Zhong F, Deng Z, Wu J, Yu W, Lü Y
Cellular and molecular neurobiology 2024 Feb 12;44(1):20
Cellular and molecular neurobiology 2024 Feb 12;44(1):20
Qualitative evaluations of reactive microglial heterogeneity in cultured porcine retina.
Johansson K, Mohlin C
Histology and histopathology 2024 Dec;39(12):1611-1620
Histology and histopathology 2024 Dec;39(12):1611-1620
Neuroprotection of celastrol against postoperative cognitive dysfunction through dampening cGAS-STING signaling.
Bu X, Guo H, Gao W, Zhang L, Hou J, Li B, Xia Z, Wang W
Experimental neurology 2024 Dec;382:114987
Experimental neurology 2024 Dec;382:114987
STING Driving Synaptic Phagocytosis of Hippocampal Microglia/Macrophages Contributes to Cognitive Impairment in Sepsis-Associated Encephalopathy in Mice.
Lv X, Jia M, Feng X, Jian JX, Yang JJ, Ma DQ, Ji MH, Diao YG, Shen JC
CNS neuroscience & therapeutics 2024 Dec;30(12):e70166
CNS neuroscience & therapeutics 2024 Dec;30(12):e70166
Ginsenoside compound K alleviates brain aging by inhibiting ferroptosis through modulation of the ASK1-MKK7-JNK signaling pathway.
Yan X, Bai X, Sun G, Duan Z, Fu R, Zeng W, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156239
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156239
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
Yang Y, Wu J, Jia L, Feng S, Qi Z, Yu H, Wu Y, Wang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
The microRNA-29ab1/Zfp36/AR Axis in the Hypothalamus Regulates Male-Typical Behaviors in Mice.
Ma J, Lin Y, Xiong W, Liu X, Pan M, Sun J, Sun Y, Li Y, Guo H, Pang G, Wang X, Ren F
International journal of molecular sciences 2024 Dec 5;25(23)
International journal of molecular sciences 2024 Dec 5;25(23)
Liu-Shen-Wan inhibits PI3K/Akt and TRPV1 signaling alleviating bone cancer pain in rats.
Zhang H, Jiang J, Chen X, Zhu F, Fu F, Chen A, Fu L, Mao D
Cancer biology & therapy 2024 Dec 31;25(1):2432098
Cancer biology & therapy 2024 Dec 31;25(1):2432098
Evaluation of the Neuroprotective Effect of Total Glycosides of Cistanche deserticola and Investigation of Novel Brain-Targeting Natural MAO-B Inhibitors.
Zhai X, Xie W, Yaqoob MD, Zhao F, Zhu HZ, Yang SS, Wang K, Wang X, Wang HC, Wang X
ACS chemical neuroscience 2024 Dec 18;15(24):4544-4558
ACS chemical neuroscience 2024 Dec 18;15(24):4544-4558
TFEB signaling promotes autophagic degradation of NLRP3 to attenuate neuroinflammation in diabetic encephalopathy.
Lin Y, Cheng L, Chen Y, Li W, Guo Q, Miao Y
American journal of physiology. Cell physiology 2024 Dec 1;327(6):C1481-C1496
American journal of physiology. Cell physiology 2024 Dec 1;327(6):C1481-C1496
γ-Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer-Related Pathologies in a Mouse Model of Down Syndrome.
Chen XQ, Becker A, Albay R, Nguyen PD, Karachentsev D, Roberts AJ, Rynearson KD, Tanzi RE, Mobley WC
Annals of neurology 2024 Aug;96(2):390-404
Annals of neurology 2024 Aug;96(2):390-404
Propofol Mitigates Sepsis-Induced Brain Injury by Inhibiting Ferroptosis Via Activation of the Nrf2/HO-1axis.
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Neurochemical research 2024 Aug;49(8):2131-2147
Neurochemical research 2024 Aug;49(8):2131-2147
Melatonin regulates microglial M1/M2 polarization via AMPKα2-mediated mitophagy in attenuating sepsis-associated encephalopathy.
Yang Y, Ke J, Cao Y, Gao Y, Lin C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117092
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117092
Effects of nanoplastic exposure during pregnancy and lactation on neurodevelopment of rat offspring.
Tian L, Zhang Y, Chen J, Liu X, Nie H, Li K, Liu H, Lai W, Shi Y, Xi Z, Lin B
Journal of hazardous materials 2024 Aug 5;474:134800
Journal of hazardous materials 2024 Aug 5;474:134800
UAMC-3203 inhibits ferroptosis and promotes functional recovery in rats with spinal cord injury.
Kan S, Feng S, Zhao X, Chen Z, Zhou M, Liu L, Zhu H, Cheng Y, Fu X, Hu W, Zhu R
Scientific reports 2024 Aug 30;14(1):20180
Scientific reports 2024 Aug 30;14(1):20180
Effect of Scaffold Geometrical Structure on Macrophage Polarization during Bone Regeneration Using Honeycomb Tricalcium Phosphate.
Takabatake K, Tsujigiwa H, Nakano K, Chang A, Piao T, Inada Y, Arashima T, Morimatsu A, Tanaka A, Kawai H, Nagatsuka H
Materials (Basel, Switzerland) 2024 Aug 19;17(16)
Materials (Basel, Switzerland) 2024 Aug 19;17(16)
Fisetin Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglia/Macrophage M1 Polarization and JAK2/STAT3 Signaling Pathway.
Ji R, Hao Z, Wang H, Su Y, Yang W, Li X, Duan L, Guan F, Ma S
Journal of agricultural and food chemistry 2024 Aug 14;72(32):17964-17976
Journal of agricultural and food chemistry 2024 Aug 14;72(32):17964-17976
Mice with type I interferon signaling deficiency are prone to epilepsy upon HSV-1 infection.
Yang W, Tang CY, Fan DY, Wang YS, Wang PG, An J, Luan GM
Virologica Sinica 2024 Apr;39(2):251-263
Virologica Sinica 2024 Apr;39(2):251-263
Oral exposure of polystyrene microplastics and doxycycline affects mice neurological function via gut microbiota disruption: The orchestrating role of fecal microbiota transplantation.
Sun H, Yang B, Zhu X, Li Q, Song E, Song Y
Journal of hazardous materials 2024 Apr 5;467:133714
Journal of hazardous materials 2024 Apr 5;467:133714
Repetitive transcranial magnetic stimulation ameliorates cognitive deficits in mice with radiation-induced brain injury by attenuating microglial pyroptosis and promoting neurogenesis via BDNF pathway.
Qin T, Guo L, Wang X, Zhou G, Liu L, Zhang Z, Ding G
Cell communication and signaling : CCS 2024 Apr 3;22(1):216
Cell communication and signaling : CCS 2024 Apr 3;22(1):216
Enriched Environment Inhibits Neurotoxic Reactive Astrocytes via JAK2-STAT3 to Promote Glutamatergic Synaptogenesis and Cognitive Improvement in Chronic Cerebral Hypoperfusion Rats.
Fan B, Lin J, Luo Q, Liao W, Hao C
Neurotoxicity research 2024 Apr 2;42(2):22
Neurotoxicity research 2024 Apr 2;42(2):22
MiR-181c-5p ameliorates learning and memory in sleep-deprived mice via HMGB1/TLR4/NF-κB pathway.
Hu Y, Hu C, Yin J, Zhong J, Deng Y, Yang G
Anais da Academia Brasileira de Ciencias 2023;95(suppl 1):e20220750
Anais da Academia Brasileira de Ciencias 2023;95(suppl 1):e20220750
PD-L1 promotes GSDMD-mediated NET release by maintaining the transcriptional activity of Stat3 in sepsis-associated encephalopathy.
Zhu CL, Xie J, Liu Q, Wang Y, Li HR, Yu CM, Li P, Deng XM, Bian JJ, Wang JF
International journal of biological sciences 2023;19(5):1413-1429
International journal of biological sciences 2023;19(5):1413-1429
Icariin reduces cognitive dysfunction induced by surgical trauma in aged rats by inhibiting hippocampal neuroinflammation.
Wang L, Peng G, Chen L, Guo M, Wang B, Zhang Y, Zhou J, Zhong M, Ye J
Frontiers in behavioral neuroscience 2023;17:1162009
Frontiers in behavioral neuroscience 2023;17:1162009
Energy intake restriction significantly improves POCD after internal fixation of tibial fractures in mice.
Xie W, Sun J, Zheng J, Xie W, Jiang C, Kang Z, Huang Y
American journal of translational research 2023;15(3):1667-1679
American journal of translational research 2023;15(3):1667-1679
Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression.
Li H, Yang C, Wei Y, Li X, Jiang W, Xu Y, Li L, Guo R, Chen D, Gao P, Zhang H, Qin H, Zhang Z, Liu X, Yan D
Theranostics 2023;13(11):3794-3813
Theranostics 2023;13(11):3794-3813
Neuroprotective Effects of Leptin on the APP/PS1 Alzheimer's Disease Mouse Model: Role of Microglial and Neuroinflammation.
Ma J, Hou YH, Liao ZY, Ma Z, Zhang XX, Wang JL, Zhu YB, Shan HL, Wang PY, Li CB, Lv YL, Wei YL, Dou JZ
Degenerative neurological and neuromuscular disease 2023;13:69-79
Degenerative neurological and neuromuscular disease 2023;13:69-79
IL-1β/IL-1R1 signaling is involved in the propagation of α-synuclein pathology of the gastrointestinal tract to the brain.
Muhammad B, Li H, Gu Y, Xue S, Gao Y, Xu Z, Fang X, Ding H, Wu F, Geng D, Niu H
Journal of neurochemistry 2023 Sep;166(5):830-846
Journal of neurochemistry 2023 Sep;166(5):830-846
Biliverdin modulates the Nrf2/A20/eEF1A2 axis to alleviate cerebral ischemia-reperfusion injury by inhibiting pyroptosis.
Bai W, Huo S, Zhou G, Li J, Yang Y, Shao J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115057
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115057
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
Lei P, Li Z, Hua Q, Song P, Gao L, Zhou L, Cai Q
International journal of molecular sciences 2023 Sep 30;24(19)
International journal of molecular sciences 2023 Sep 30;24(19)
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Hu S, Wang X, Yang X, Ouyang S, Pan X, Fu Y, Wu S
Neuroscience 2023 Sep 1;527:37-51
Neuroscience 2023 Sep 1;527:37-51
Clemastine fumarate attenuates tauopathy and meliorates cognition in hTau mice via autophagy enhancement.
Zhu J, Jiang X, Chang Y, Wu Y, Sun S, Wang C, Zheng S, Wang M, Yao Y, Li G, Ma R
International immunopharmacology 2023 Oct;123:110649
International immunopharmacology 2023 Oct;123:110649
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway.
Li H, Zhang C, Zhou Y, Deng Y, Zheng X, Xue X
Aging 2023 Oct 26;15(20):11639-11653
Aging 2023 Oct 26;15(20):11639-11653
Long-term normalization of calcineurin activity in model mice rescues Pin1 and attenuates Alzheimer's phenotypes without blocking peripheral T cell IL-2 response.
Stallings NR, O'Neal MA, Hu J, Shen ZJ, Malter JS
Alzheimer's research & therapy 2023 Oct 17;15(1):179
Alzheimer's research & therapy 2023 Oct 17;15(1):179
Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation.
Kanwore K, Kanwore K, Guo X, Xia Y, Zhou H, Zhang L, Adzika GK, Joseph AA, Abiola AA, Mu P, Kambey PA, Noah MLN, Gao D
Inflammation and regeneration 2023 Oct 13;43(1):49
Inflammation and regeneration 2023 Oct 13;43(1):49
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Tung TH, Lai WD, Lee HC, Su KP, Panunggal B, Huang SY
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14550-14561
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14550-14561
Aluminum exposure induces central nervous system impairment via activating NLRP3-medicated pyroptosis pathway.
Hao W, Zhu X, Liu Z, Song Y, Wu S, Lu X, Yang J, Jin C
Ecotoxicology and environmental safety 2023 Oct 1;264:115401
Ecotoxicology and environmental safety 2023 Oct 1;264:115401
NCBP1 Improves Cognitive Function in Mice by Reducing Oxidative Stress, Neuronal Loss, and Glial Activation After Status Epilepticus.
Gao X, You Z, Huang C, Liu Z, Tan Z, Li J, Liu Y, Liu X, Wei F, Fan Z, Qi S, Sun J
Molecular neurobiology 2023 Nov;60(11):6676-6688
Molecular neurobiology 2023 Nov;60(11):6676-6688
Multi-parametric MRI assessment of melatonin regulating the polarization of microglia in rats after cerebral ischemia/reperfusion injury.
Li Z, Gong P, Zhang M, Li C, Xiao P, Yu M, Wang X, An L, Bi F, Song X, Wang X
Brain research bulletin 2023 Nov;204:110807
Brain research bulletin 2023 Nov;204:110807
The bexarotene derivative OAB-14 ameliorates cognitive decline in APP/PS1 transgenic mice by suppressing microglia-mediated neuroinflammation through the PPAR-γ pathway.
Zhang F, Cao RL, Liu P, Chi TY, Ji XF, Zheng ZH, Chen GL, Zou LB
International immunopharmacology 2023 Nov;124(Pt A):110911
International immunopharmacology 2023 Nov;124(Pt A):110911
OTUD1 ameliorates cerebral ischemic injury through inhibiting inflammation by disrupting K63-linked deubiquitination of RIP2.
Zheng S, Li Y, Song X, Wu M, Yu L, Huang G, Liu T, Zhang L, Shang M, Zhu Q, Gao C, Chen L, Liu H
Journal of neuroinflammation 2023 Nov 27;20(1):281
Journal of neuroinflammation 2023 Nov 27;20(1):281
Nobiletin Mitigates D-Galactose-Induced Memory Impairment via Improving Hippocampal Neurogenesis in Mice.
Xiong W, Li R, Li B, Wang X, Wang H, Sun Y, Wang X, Li Y, Ren F
Nutrients 2023 May 8;15(9)
Nutrients 2023 May 8;15(9)
Multi-omics analysis of a drug-induced model of bipolar disorder in zebrafish.
Li Y, Zhang L, Mao M, He L, Wang T, Pan Y, Zhao X, Li Z, Mu X, Qian Y, Qiu J
iScience 2023 May 19;26(5):106744
iScience 2023 May 19;26(5):106744
Adiponectin Attenuates Splenectomy-Induced Cognitive Deficits by Neuroinflammation and Oxidative Stress via TLR4/MyD88/NF-κb Signaling Pathway in Aged Rats.
Zhang Z, Guo L, Yang F, Peng S, Wang D, Lai X, Su B, Xie H
ACS chemical neuroscience 2023 May 17;14(10):1799-1809
ACS chemical neuroscience 2023 May 17;14(10):1799-1809
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Jiang F, Guo Y, Hu L, Zhang M, Meng J, Si Y, Shi H
Brain research 2023 May 1;1806:148299
Brain research 2023 May 1;1806:148299
Deep Sc-RNA sequencing decoding the molecular dynamic architecture of the human retina.
Huang L, Li R, Ye L, Zhang S, Tian H, Du M, Qu C, Li S, Li J, Yang M, Wu B, Chen R, Huang G, Zhong L, Yang H, Yu M, Shi Y, Wang C, Zhang H, Chen W, Yang Z
Science China. Life sciences 2023 Mar;66(3):496-515
Science China. Life sciences 2023 Mar;66(3):496-515
Novel 2,6-disubstituted benzofuran-3-one analogues improve cerebral ischemia/reperfusion injury via neuroprotective and antioxidative effects.
Yang Z, Luo G, Ying Y, Li H, Wan Y, Xu G, Li M, Xian Y, Feng Y, Fang Y
Bioorganic chemistry 2023 Mar;132:106346
Bioorganic chemistry 2023 Mar;132:106346
Treatment with Granulocyte-Macrophage Colony-Stimulating Factor Reduces Viral Titers in the Brains of West Nile Virus-Infected Mice and Improves Survival.
Stonedahl S, Leser JS, Clarke P, Potter H, Boyd TD, Tyler KL
Journal of virology 2023 Mar 30;97(3):e0180522
Journal of virology 2023 Mar 30;97(3):e0180522
Selective Targeting of Class I HDAC Reduces Microglial Inflammation in the Entorhinal Cortex of Young APP/PS1 Mice.
Wang C, Shen D, Hu Y, Chen J, Liu J, Huang Y, Yu X, Chu H, Zhang C, Yin L, Liu Y, Ma H
International journal of molecular sciences 2023 Mar 2;24(5)
International journal of molecular sciences 2023 Mar 2;24(5)
Neuronal loss of NCLX-dependent mitochondrial calcium efflux mediates age-associated cognitive decline.
Jadiya P, Cohen HM, Kolmetzky DW, Kadam AA, Tomar D, Elrod JW
iScience 2023 Mar 17;26(3):106296
iScience 2023 Mar 17;26(3):106296
Polydatin Alleviates Chronic Stress-Induced Depressive and Anxiety-like Behaviors in a Mouse Model.
Wang J, Men Y, Wang Z
ACS chemical neuroscience 2023 Mar 1;14(5):977-987
ACS chemical neuroscience 2023 Mar 1;14(5):977-987
Blocking Two-Pore Domain Potassium Channel TREK-1 Inhibits the Activation of A1-Like Reactive Astrocyte Through the NF-κB Signaling Pathway in a Rat Model of Major Depressive Disorder.
Cong T, Sun Y, Zhou Y, Wu H, Li L, Chu Z, Chen X, Li J, Zhao D, Wang Y, Liu Y, Yin S, Xiao Z
Neurochemical research 2023 Jun;48(6):1737-1754
Neurochemical research 2023 Jun;48(6):1737-1754
The internal ribosome entry site determines the neurotropic potential of enterovirus A71.
Wu GH, Lee KM, Kao CY, Shih SR
Microbes and infection 2023 Jun;25(5):105107
Microbes and infection 2023 Jun;25(5):105107
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Guo L, Jiang ZM, Zhan YJ, Pan W, Wu QW, Song FX, Zhou X, Zhou XY, Liu LJ, Wang JT
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Thymopentin (TP-5) prevents lipopolysaccharide-induced neuroinflammation and dopaminergic neuron injury by inhibiting the NF-κB/NLRP3 signaling pathway.
Peng SJ, Feng Y, Li X, Wang XX, Wang Y, Zhou BT, Liu Y, Liu T, Wu YC
International immunopharmacology 2023 Jun;119:110109
International immunopharmacology 2023 Jun;119:110109
Intermittent hypoxia exacerbated depressive and anxiety-like behaviors in the bleomycin-induced pulmonary fibrosis mice.
Xiong M, Wu Z, Zhao Y, Zhao D, Pan Z, Wu X, Liu W, Hu K
Brain research bulletin 2023 Jun 15;198:55-64
Brain research bulletin 2023 Jun 15;198:55-64
Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice.
Lyraki R, Grabek A, Tison A, Weerasinghe Arachchige LC, Peitzsch M, Bechmann N, Youssef SA, de Bruin A, Bakker ERM, Claessens F, Chaboissier MC, Schedl A
Disease models & mechanisms 2023 Jun 1;16(6)
Disease models & mechanisms 2023 Jun 1;16(6)
Emodin attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis.
Cui YR, Bu ZQ, Yu HY, Yan LL, Feng J
Neural regeneration research 2023 Jul;18(7):1535-1541
Neural regeneration research 2023 Jul;18(7):1535-1541
Parthenolide alleviates microglia-mediated neuroinflammation via MAPK/TRIM31/NLRP3 signaling to ameliorate cognitive disorder.
Fan M, Wang C, Zhao X, Jiang Y, Wang C
International immunopharmacology 2023 Jul;120:110287
International immunopharmacology 2023 Jul;120:110287
ONO-2506 Can Delay Levodopa-induced Dyskinesia in the Early Stage.
Yuan Y, Zhang X, Wu Y, Lian P, Cao X, Xu Y
Neuroscience 2023 Jul 15;523:61-79
Neuroscience 2023 Jul 15;523:61-79
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Wang CQ, Su Z, Dai CG, Song JL, Qian B
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Heterozygous disruption of beclin 1 alleviates neurotoxicity induced by sub-chronic exposure of arsenite in mice.
Li D, Qin Q, Xia Y, Cheng S, Zhang J, Duan X, Qin X, Tian X, Mao L, Qiu J, Jiang X, Zou Z, Chen C
Neurotoxicology 2023 Jan;94:11-23
Neurotoxicology 2023 Jan;94:11-23
Fra-1 induces apoptosis and neuroinflammation by targeting S100A8 to modulate TLR4 pathways in spinal cord ischemia/reperfusion injury.
Chen Y, Dong Y, Zhang ZL, Han J, Chen FS, Tong XY, Ma H
Brain pathology (Zurich, Switzerland) 2023 Jan;33(1):e13113
Brain pathology (Zurich, Switzerland) 2023 Jan;33(1):e13113
Fingolimod ameliorates schizophrenia-like cognitive impairments induced by phencyclidine in male rats.
Yu X, Qi X, Wei L, Zhao L, Deng W, Guo W, Wang Q, Ma X, Hu X, Ni P, Li T
British journal of pharmacology 2023 Jan;180(2):161-173
British journal of pharmacology 2023 Jan;180(2):161-173
Microglia in Cultured Porcine Retina: Qualitative Immunohistochemical Analyses of Reactive Microglia in the Outer Retina.
Johansson K, Mohlin C
International journal of molecular sciences 2023 Jan 3;24(1)
International journal of molecular sciences 2023 Jan 3;24(1)
Aluminum induces neuroinflammation via P2X7 receptor activating NLRP3 inflammasome pathway.
Zhu X, Hao W, Liu Z, Song Y, Hao C, Wu S, Lu X, Yang J, Jin C
Ecotoxicology and environmental safety 2023 Jan 1;249:114373
Ecotoxicology and environmental safety 2023 Jan 1;249:114373
ASK1 inhibitor NQDI‑1 decreases oxidative stress and neuroapoptosis via the ASK1/p38 and JNK signaling pathway in early brain injury after subarachnoid hemorrhage in rats.
Duan J, Yuan W, Jiang J, Wang J, Yan X, Liu F, Liu A
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
CXCR4 knockout induces neuropathological changes in the MPTP-lesioned model of Parkinson's disease.
Ma J, Dong L, Chang Q, Chen S, Zheng J, Li D, Wu S, Yang H, Li X
Biochimica et biophysica acta. Molecular basis of disease 2023 Feb;1869(2):166597
Biochimica et biophysica acta. Molecular basis of disease 2023 Feb;1869(2):166597
Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke.
Zhu ZH, Jia F, Ahmed W, Zhang GL, Wang H, Lin CQ, Chen WH, Chen LK
Neural regeneration research 2023 Feb;18(2):404-409
Neural regeneration research 2023 Feb;18(2):404-409
Prenatal Sevoflurane Exposure Impairs the Learning and Memory of Rat Offspring via HMGB1-Induced NLRP3/ASC Inflammasome Activation.
Shan Y, Liu P, Zhou Y, Ding X, Liu H, Yang J
ACS chemical neuroscience 2023 Feb 15;14(4):699-708
ACS chemical neuroscience 2023 Feb 15;14(4):699-708
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Guo TT, Zhang Z, Sun Y, Zhu RY, Wang FX, Ma LJ, Jiang L, Liu HD
Nutrients 2023 Feb 13;15(4)
Nutrients 2023 Feb 13;15(4)
Microglia trigger the structural plasticity of GABAergic neurons in the hippocampal CA1 region of a lipopolysaccharide-induced neuroinflammation model.
Chen J, Wang T, Zhou Y, Hong Y, Zhang S, Zhou Z, Jiang A, Liu D
Experimental neurology 2023 Dec;370:114565
Experimental neurology 2023 Dec;370:114565
Antinociceptive and neuroprotective effect of echinacoside on peripheral neuropathic pain in mice through inhibiting P2X7R/FKN/CX3CR1 pathway.
Liu N, Zhang GX, Zhu CH, Lan XB, Tian MM, Zheng P, Peng XD, Li YX, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115675
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115675
Ischemic Preconditioning Alleviates Cerebral Ischemia-Reperfusion Injury by Interfering With Glycocalyx.
Zhang YN, Wu Q, Zhang NN, Chen HS
Translational stroke research 2023 Dec;14(6):929-940
Translational stroke research 2023 Dec;14(6):929-940
Spatiotemporal expression patterns of ZBP1 in the brain of mouse experimental stroke model.
Mutoh T, Kikuchi H, Jitsuishi T, Kitajo K, Yamaguchi A
Journal of chemical neuroanatomy 2023 Dec;134:102362
Journal of chemical neuroanatomy 2023 Dec;134:102362
Ilexchinene, a new seco-ursane triterpenoid from the leaves of Ilex chinensis with therapeutic effect on neuroinflammation by attenuating the MAPK/NF-κB signaling pathway.
Shao S, Li R, Wang K, Xia W, Cui B, Li S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155110
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155110
Debris generated by laser and/or balloon cause cerebral infarction with different severity.
Yang K, Tan J, Deng Y, Jiang S, Tang J, Shi W, Yu B
Lasers in medical science 2023 Dec 23;39(1):15
Lasers in medical science 2023 Dec 23;39(1):15
Metformin promotes Schwann cell remyelination, preserves neural tissue and improves functional recovery after spinal cord injury.
Huang Z, Lin J, Jiang H, Lin W, Huang Z, Chen J, Xiao W, Lin Q, Wang J, Wen S, Zhu Q, Liu J
Neuropeptides 2023 Aug;100:102348
Neuropeptides 2023 Aug;100:102348
Cognitive Alterations in Old Mice Are Associated with Intestinal Barrier Dysfunction and Induced Toll-like Receptor 2 and 4 Signaling in Different Brain Regions.
Brandt A, Kromm F, Hernández-Arriaga A, Martínez Sánchez I, Bozkir HÖ, Staltner R, Baumann A, Camarinha-Silva A, Heijtz RD, Bergheim I
Cells 2023 Aug 27;12(17)
Cells 2023 Aug 27;12(17)
Effects of Fisetin Treatment on Cellular Senescence of Various Tissues and Organs of Old Sheep.
Huard CA, Gao X, Dey Hazra ME, Dey Hazra RO, Lebsock K, Easley JT, Millett PJ, Huard J
Antioxidants (Basel, Switzerland) 2023 Aug 21;12(8)
Antioxidants (Basel, Switzerland) 2023 Aug 21;12(8)
Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition.
Ma H, Zhang X, Liu L, Huang Y, Sun S, Chen K, Xin Q, Liu P, Yan Y, Wang Y, Li Y, Liu H, Zhao R, Tan K, Chen X, Yuan X, Li Y, Liu Y, Dai H, Liu C, Wang H, Zhang XD
Science advances 2023 Aug 2;9(31):eadh7828
Science advances 2023 Aug 2;9(31):eadh7828
Ketogenic diet alleviates brain iron deposition and cognitive dysfunction via Nrf2-mediated ferroptosis pathway in APP/PS1 mouse.
Qin Y, Bai D, Tang M, Zhang M, Zhao L, Li J, Yang R, Jiang G
Brain research 2023 Aug 1;1812:148404
Brain research 2023 Aug 1;1812:148404
Modulation of the endoplasmic reticulum stress and unfolded protein response mitigates the behavioral effects of early-life stress.
Solarz-Andrzejewska A, Majcher-Maślanka I, Kryst J, Chocyk A
Pharmacological reports : PR 2023 Apr;75(2):293-319
Pharmacological reports : PR 2023 Apr;75(2):293-319
Poly-L-ornithine blocks the inhibitory effects of fibronectin on oligodendrocyte differentiation and promotes myelin repair.
Xiong YJ, Soomro SH, Huang ZH, Yu PP, Ping J, Fu H
Neural regeneration research 2023 Apr;18(4):832-839
Neural regeneration research 2023 Apr;18(4):832-839
Allograft inflammatory factor 1 is a potential diagnostic, immunological, and prognostic biomarker in pan-cancer.
Liu X, Zhang D, Hu J, Xu S, Xu C, Shen Y
Aging 2023 Apr 3;15(7):2582-2609
Aging 2023 Apr 3;15(7):2582-2609
Mitochondrial-targeting fluorescent small molecule IR-780 alleviates radiation-induced brain injury.
Zhang C, Zheng J, Chen W, Yang W, Tan X, Fan X, Shen G, Qu L, Chen Z, Shi C
Brain research 2023 Apr 15;1805:148285
Brain research 2023 Apr 15;1805:148285
Ferulic acid produces neuroprotection against radiation-induced neuroinflammation by affecting NLRP3 inflammasome activation.
Liu G, Nie Y, Huang C, Zhu G, Zhang X, Hu C, Li Z, Gao Y, Ma Z
International journal of radiation biology 2022;98(9):1442-1451
International journal of radiation biology 2022;98(9):1442-1451
Probiotic Lactobacillus rhamnosus GR-1 supplementation attenuates Pb-induced learning and memory deficits by reshaping the gut microbiota.
Gu X, Bi N, Wang T, Huang C, Wang R, Xu Y, Wang HL
Frontiers in nutrition 2022;9:934118
Frontiers in nutrition 2022;9:934118
Effects of Electroacupuncture on the Correlation between Serum and Central Immunity in AD Model Animals.
Jiang J, Wang Z, Yu R, Yang J, Tian H, Liu H, Wang S, Li Z, Zhu X
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3478847
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3478847
The Role of Microglia/Macrophages Activation and TLR4/NF-κB/MAPK Pathway in Distraction Spinal Cord Injury-Induced Inflammation.
Liang W, Han B, Hai Y, Liu Y, Liu X, Yang J, Sun D, Yin P
Frontiers in cellular neuroscience 2022;16:926453
Frontiers in cellular neuroscience 2022;16:926453
Anomalous Levels of CD47/Signal Regulatory Protein Alpha in the Hippocampus Lead to Excess Microglial Engulfment in Mouse Model of Perioperative Neurocognitive Disorders.
Shui M, Sun Y, Lin D, Xue Z, Liu J, Wu A, Wei C
Frontiers in neuroscience 2022;16:788675
Frontiers in neuroscience 2022;16:788675
Neuroinflammation in a Rat Model of Tourette Syndrome.
Zhongling K, Yanhui C, Guofeng C, Yanyan L
Frontiers in behavioral neuroscience 2022;16:710116
Frontiers in behavioral neuroscience 2022;16:710116
Transcranial near-infrared laser improves postoperative neurocognitive disorder in aged mice via SIRT3/AMPK/Nrf2 pathway.
Zhong J, Zhao L, Wu W, Chen J, Yuan S, Zhang X, Wang Z
Frontiers in neuroscience 2022;16:1100915
Frontiers in neuroscience 2022;16:1100915
Dexmedetomidine post-conditioning protects blood-brain barrier integrity by modulating microglia/macrophage polarization via inhibiting NF-κB signaling pathway in intracerebral hemorrhage.
Guo H, Zhang W, Wang Z, Li Z, Zhou J, Yang Z
Frontiers in molecular neuroscience 2022;15:977941
Frontiers in molecular neuroscience 2022;15:977941
Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.
Peng Q, Zhang G, Guo X, Dai L, Xiong M, Zhang Z, Chen L, Zhang Z
Frontiers in molecular neuroscience 2022;15:1046992
Frontiers in molecular neuroscience 2022;15:1046992
Lipid profiles in the cerebrospinal fluid of rats with 6-hydroxydopamine-induced lesions as a model of Parkinson's disease.
Qiu J, Peng G, Tang Y, Li S, Liu Z, Zheng J, Wang Y, Liu H, Wei L, Su Y, Lin Y, Dai W, Zhang Z, Chen X, Ding L, Guo W, Zhu X, Xu P, Mo M
Frontiers in aging neuroscience 2022;14:1077738
Frontiers in aging neuroscience 2022;14:1077738
LPS activates neuroinflammatory pathways to induce depression in Parkinson's disease-like condition.
Zhang J, Xue B, Jing B, Tian H, Zhang N, Li M, Lu L, Chen L, Diao H, Chen Y, Wang M, Li X
Frontiers in pharmacology 2022;13:961817
Frontiers in pharmacology 2022;13:961817
α7 Nicotinic Acetylcholine Receptor May Be a Pharmacological Target for Perioperative Neurocognitive Disorders.
Wei P, Lyu W, Xu L, Feng H, Zhou H, Li J
Frontiers in pharmacology 2022;13:907713
Frontiers in pharmacology 2022;13:907713
Acupuncture Ameliorates Depressive Behaviors by Modulating the Expression of Hippocampal Iba-1 and HMGB1 in Rats Exposed to Chronic Restraint Stress.
Chen L, Jiang H, Bao T, Wang Y, Meng H, Sun Y, Liu P, Quan S, Li W, Qi S, Ren X
Frontiers in psychiatry 2022;13:903004
Frontiers in psychiatry 2022;13:903004
DAPT Attenuates Cadmium-Induced Toxicity in Mice by Inhibiting Inflammation and the Notch/HES-1 Signaling Axis.
Yang JY, Shen DY, Wang J, Dai JF, Qin XY, Hu Y, Lan R
Frontiers in pharmacology 2022;13:902796
Frontiers in pharmacology 2022;13:902796
Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice.
Zhao P, Li X, Yang Q, Lu Y, Wang G, Yang H, Dong J, Zhang H
Frontiers in pharmacology 2022;13:1038802
Frontiers in pharmacology 2022;13:1038802
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Yang L, Wu C, Parker E, Li Y, Dong Y, Tucker L, Brann DW, Lin HW, Zhang Q
Theranostics 2022;12(5):2205-2231
Theranostics 2022;12(5):2205-2231
Continuous theta-burst stimulation enhances and sustains neurogenesis following ischemic stroke.
Zong X, Gu J, Zhou S, Ding D, Hu Y, Tucker L, Huang Z, Geng D, Gao D
Theranostics 2022;12(13):5710-5726
Theranostics 2022;12(13):5710-5726
Oral SARS-CoV-2 Inoculation Causes Nasal Viral Infection Leading to Olfactory Bulb Infection: An Experimental Study.
Ueha R, Ito T, Furukawa R, Kitabatake M, Ouji-Sageshima N, Ueha S, Koyama M, Uranaka T, Kondo K, Yamasoba T
Frontiers in cellular and infection microbiology 2022;12:924725
Frontiers in cellular and infection microbiology 2022;12:924725
Intestinal Flora Composition Determines Microglia Activation and Improves Epileptic Episode Progress.
Ding X, Zhou J, Zhao L, Chen M, Wang S, Zhang M, Zhang X, Jiang G
Frontiers in cellular and infection microbiology 2022;12:835217
Frontiers in cellular and infection microbiology 2022;12:835217
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhu C, Tian M, Liu N, Ma L, Lan X, Yang J, Du J, Ma H, Li Y, Zheng P, Yu J, Peng X
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
Apelin-13 reduces lipopolysaccharide-induced neuroinflammation and cognitive impairment via promoting glucocorticoid receptor expression and nuclear translocation.
Hu S, Shen P, Chen B, Tian SW, You Y
Neuroscience letters 2022 Sep 25;788:136850
Neuroscience letters 2022 Sep 25;788:136850
Celastrol inhibits pathologic neovascularization in oxygen-induced retinopathy by targeting the miR-17-5p/HIF-1α/VEGF pathway.
Zhao K, Jiang Y, Zhang J, Shi J, Zheng P, Yang C, Chen Y
Cell cycle (Georgetown, Tex.) 2022 Oct;21(19):2091-2108
Cell cycle (Georgetown, Tex.) 2022 Oct;21(19):2091-2108
Panax notoginseng saponins alleviates inflammation induced by microglial activation and protects against ischemic brain injury via inhibiting HIF-1α/PKM2/STAT3 signaling.
Gao J, Yao M, Zhang W, Yang B, Yuan G, Liu JX, Zhang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113479
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113479
Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2-Signal Transducer and Activator of Transcription 6 Pathway.
Wang J, Zhang G, Yang Y, Zhang X, Shi K, Zhang X, Yan T, Jia Y
Journal of agricultural and food chemistry 2022 Nov 9;70(44):14157-14169
Journal of agricultural and food chemistry 2022 Nov 9;70(44):14157-14169
6-methoxyflavone suppresses neuroinflammation in lipopolysaccharide- stimulated microglia through the inhibition of TLR4/MyD88/p38 MAPK/NF-κB dependent pathways and the activation of HO-1/NQO-1 signaling.
Chen WF, Shih YH, Liu HC, Cheng CI, Chang CI, Chen CY, Lin IP, Lin MY, Lee CH
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154025
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154025
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
Yang G, Cao Y, Wang P, Mei L, Chen J, Lu W
The Journal of surgical research 2022 May;273:247-254
The Journal of surgical research 2022 May;273:247-254
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.
Guo L, Jiang ZM, Sun RX, Pang W, Zhou X, Du ML, Chen MX, Lv X, Wang JT
Brain research bulletin 2022 May;182:111-117
Brain research bulletin 2022 May;182:111-117
Genetic lesions of the noradrenergic system trigger induction of oxidative stress and inflammation in the ventral midbrain.
Barut J, Rafa-Zabłocka K, Jurga AM, Bagińska M, Nalepa I, Parlato R, Kreiner G
Neurochemistry international 2022 May;155:105302
Neurochemistry international 2022 May;155:105302
The effect of prolonged formalin fixation on the expression of proteins in human brain tissues.
Wu X, Deng C, Su Y, Zhang C, Chen M, Tian K, Wu H, Xu S
Acta histochemica 2022 May;124(4):151879
Acta histochemica 2022 May;124(4):151879
Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation.
Yang S, Du Y, Zhao X, Tang Q, Su W, Hu Y, Yu P
International journal of molecular sciences 2022 May 11;23(10)
International journal of molecular sciences 2022 May 11;23(10)
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Liu MX, Luo L, Fu JH, He JY, Chen MY, He ZJ, Jia J
Experimental neurology 2022 Mar;349:113952
Experimental neurology 2022 Mar;349:113952
Gut microbiota shapes social dominance through modulating HDAC2 in the medial prefrontal cortex.
Wang T, Xu J, Xu Y, Xiao J, Bi N, Gu X, Wang HL
Cell reports 2022 Mar 8;38(10):110478
Cell reports 2022 Mar 8;38(10):110478
Salidroside alleviates cadmium-induced toxicity in mice by restoring the notch/HES-1 and RIP1-driven inflammatory signaling axis.
Shu XM, Hu Y, Fang X, Wang J, Qin XY, Lan R
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Jun;71(5-6):615-626
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Jun;71(5-6):615-626
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
Kou L, Chi X, Sun Y, Han C, Wan F, Hu J, Yin S, Wu J, Li Y, Zhou Q, Zou W, Xiong N, Huang J, Xia Y, Wang T
Journal of neuroinflammation 2022 Jun 6;19(1):133
Journal of neuroinflammation 2022 Jun 6;19(1):133
Therapeutic Effect of Mitochondrial Division Inhibitor-1 (Mdivi-1) on Hyperglycemia-Exacerbated Early and Delayed Brain Injuries after Experimental Subarachnoid Hemorrhage.
Chung CL, Huang YH, Lin CJ, Chong YB, Wu SC, Chai CY, Tsai HP, Kwan AL
International journal of molecular sciences 2022 Jun 22;23(13)
International journal of molecular sciences 2022 Jun 22;23(13)
Neuroglobin alleviates the neurotoxicity of sevoflurane to fetal rats by inhibiting neuroinflammation and affecting microglial polarization.
Zhang Y, Gao Y, Yang F, Wu X, Tang Z, Liu H
Brain research bulletin 2022 Jun 1;183:142-152
Brain research bulletin 2022 Jun 1;183:142-152
Ppp4r3a deficiency leads to depression-like behaviors in mice by modulating the synthesis of synaptic proteins.
Gao F, Liu A, Qi X, Wang M, Chen X, Wei S, Gao S, Sun Y, Sun P, Li X, Sun W, Li J, Liu Q
Disease models & mechanisms 2022 Jun 1;15(6)
Disease models & mechanisms 2022 Jun 1;15(6)
Astragalin attenuates AlCl(3)/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation.
Hu Y, Fang X, Wang J, Ren TT, Zhao YY, Dai JF, Qin XY, Lan R
Neurotoxicology 2022 Jul;91:60-68
Neurotoxicology 2022 Jul;91:60-68
MG53 protein rejuvenates hUC-MSCs and facilitates their therapeutic effects in AD mice by activating Nrf2 signaling pathway.
Ma S, Zhou X, Wang Y, Li Z, Wang Y, Shi J, Guan F
Redox biology 2022 Jul;53:102325
Redox biology 2022 Jul;53:102325
Icariin attenuates ischaemic stroke through suppressing inflammation mediated by endoplasmic reticulum stress signalling pathway in rats.
Zheng J, Liao Y, Xu Y, Mo Z
Clinical and experimental pharmacology & physiology 2022 Jul;49(7):719-730
Clinical and experimental pharmacology & physiology 2022 Jul;49(7):719-730
Neuroprotective effects of CysLTR antagonist on Streptococcus pneumoniae-induced meningitis in rats.
Yu S, Chen X, Li X, Yan J, Jiang Y
Experimental and therapeutic medicine 2022 Jul;24(1):443
Experimental and therapeutic medicine 2022 Jul;24(1):443
Delayed administration of nafamostat mesylate inhibits thrombin-mediated blood-spinal cord barrier breakdown during acute spinal cord injury in rats.
Zhao C, Zhou T, Zhao X, Pang Y, Li W, Fan B, Li M, Liu X, Ma L, Zhang J, Sun C, Shen W, Kong X, Yao X, Feng S
Journal of neuroinflammation 2022 Jul 16;19(1):189
Journal of neuroinflammation 2022 Jul 16;19(1):189
Neonatal microglia and proteinase inhibitors-treated adult microglia improve traumatic brain injury in rats by resolving the neuroinflammation.
Zheng P, Bai Q, Feng J, Zhao B, Duan J, Zhao L, Liu N, Ren D, Zou S, Chen W
Bioengineering & translational medicine 2022 Jan;7(1):e10249
Bioengineering & translational medicine 2022 Jan;7(1):e10249
The intestinal microbial metabolite nicotinamide n-oxide prevents herpes simplex encephalitis via activating mitophagy in microglia.
Li F, Wang Y, Song X, Wang Z, Jia J, Qing S, Huang L, Wang Y, Wang S, Ren Z, Zheng K, Wang Y
Gut microbes 2022 Jan-Dec;14(1):2096989
Gut microbes 2022 Jan-Dec;14(1):2096989
Malignant Melanoma-Derived Exosomes Induce Endothelial Damage and Glial Activation on a Human BBB Chip Model.
Wang P, Wu Y, Chen W, Zhang M, Qin J
Biosensors 2022 Jan 31;12(2)
Biosensors 2022 Jan 31;12(2)
Islet amyloid polypeptide cross-seeds tau and drives the neurofibrillary pathology in Alzheimer's disease.
Zhang G, Meng L, Wang Z, Peng Q, Chen G, Xiong J, Zhang Z
Molecular neurodegeneration 2022 Jan 29;17(1):12
Molecular neurodegeneration 2022 Jan 29;17(1):12
2-PMAP Ameliorates Cerebral Vasospasm and Brain Injury after Subarachnoid Hemorrhage by Regulating Neuro-Inflammation in Rats.
Wu CH, Tsai HP, Su YF, Tsai CY, Lu YY, Lin CL
Cells 2022 Jan 12;11(2)
Cells 2022 Jan 12;11(2)
Coeloglossum viride var. bracteatum extract attenuates Aβ-induced toxicity by inhibiting RIP1-driven inflammation and necroptosis.
Li XX, Lang XY, Ren TT, Wang J, Lan R, Qin XY
Journal of ethnopharmacology 2022 Jan 10;282:114606
Journal of ethnopharmacology 2022 Jan 10;282:114606
Isoliquiritigenin attenuates neuroinflammation in mice model of Parkinson's disease by promoting Nrf2/NQO-1 pathway.
Huang L, Han Y, Zhou Q, Sun Z, Yan J
Translational neuroscience 2022 Jan 1;13(1):301-308
Translational neuroscience 2022 Jan 1;13(1):301-308
Neuroprotective effects of liraglutide against inflammation through the AMPK/NF-κB pathway in a mouse model of Parkinson's disease.
Cao B, Zhang Y, Chen J, Wu P, Dong Y, Wang Y
Metabolic brain disease 2022 Feb;37(2):451-462
Metabolic brain disease 2022 Feb;37(2):451-462
Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.
Lu T, Li H, Zhou Y, Wei W, Ding L, Zhan Z, Liu W, Tao J, Xue X
Journal of neuroinflammation 2022 Feb 7;19(1):37
Journal of neuroinflammation 2022 Feb 7;19(1):37
Connexin43 inhibition attenuated dopaminergic neuronal loss in the lipopolysaccharide-induced mice model of Parkinson's disease.
Zhao Y, Qi Y, Li Q, Quan H, Liu D, Zhou H
Neuroscience letters 2022 Feb 6;771:136471
Neuroscience letters 2022 Feb 6;771:136471
Neurotoxicological profile of the hallucinogenic compound 25I-NBOMe.
Herian M, Wojtas A, Maćkowiak M, Wawrzczak-Bargiela A, Solarz A, Bysiek A, Madej K, Gołembiowska K
Scientific reports 2022 Feb 21;12(1):2939
Scientific reports 2022 Feb 21;12(1):2939
HIV-1 Tat drives the Fabp4/NF-κB feedback loop in microglia to mediate inflammatory response and neuronal apoptosis.
Zhou X, Zhou S, Tao J, Gao Y, Meng G, Cao D, Gao L
Journal of neurovirology 2022 Dec;28(4-6):483-496
Journal of neurovirology 2022 Dec;28(4-6):483-496
MMP-12 knockdown prevents secondary brain damage after ischemic stroke in mice.
Arruri V, Chokkalla AK, Jeong S, Chelluboina B, Mehta SL, Veeravalli KK, Vemuganti R
Neurochemistry international 2022 Dec;161:105432
Neurochemistry international 2022 Dec;161:105432
Fluoxetine shows neuroprotective effects against LPS-induced neuroinflammation via the Notch signaling pathway.
Zhang J, Zhang N, Lei J, Jing B, Li M, Tian H, Xue B, Li X
International immunopharmacology 2022 Dec;113(Pt A):109417
International immunopharmacology 2022 Dec;113(Pt A):109417
Postmortem 7T MRI for guided histopathology and evaluation of cerebrovascular disease.
Lahna D, Roese N, Woltjer R, Boespflug EL, Schwartz D, Grinstead J, Dodge HH, Wall R, Kaye JA, Rooney WD, Silbert LC
Journal of neuropathology and experimental neurology 2022 Dec 19;82(1):57-70
Journal of neuropathology and experimental neurology 2022 Dec 19;82(1):57-70
Aberrant neural activity in prefrontal pyramidal neurons lacking TDP-43 precedes neuron loss.
Liang B, Thapa R, Zhang G, Moffitt C, Zhang Y, Zhang L, Johnston A, Ruby HP, Barbera G, Wong PC, Zhang Z, Chen R, Lin DT, Li Y
Progress in neurobiology 2022 Aug;215:102297
Progress in neurobiology 2022 Aug;215:102297
A pilot study: Gut microbiota, metabolism and inflammation in hypertensive intracerebral haemorrhage.
Li W, Wu LX, Huang BS, Yang LJ, Huang JQ, Li ZS, Jiao J, Cheng T, Li D, Xiong Y
Journal of applied microbiology 2022 Aug;133(2):972-986
Journal of applied microbiology 2022 Aug;133(2):972-986
Blocking Hepatoma-Derived Growth Factor Attenuates Vasospasm and Neuron Cell Apoptosis in Rats Subjected to Subarachnoid Hemorrhage.
Chung CL, Wu CH, Huang YH, Wu SC, Chai CY, Tsai HP, Kwan AL
Translational stroke research 2022 Apr;13(2):300-310
Translational stroke research 2022 Apr;13(2):300-310
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
Qiu J, Chen Y, Zhuo J, Zhang L, Liu J, Wang B, Sun D, Yu S, Lou H
Neuropharmacology 2022 Apr 1;207:108963
Neuropharmacology 2022 Apr 1;207:108963
Photobiomodulation Therapy Attenuates Anxious-Depressive-Like Behavior in the TgF344 Rat Model.
Yang L, Wu C, Tucker L, Dong Y, Li Y, Xu P, Zhang Q
Journal of Alzheimer's disease : JAD 2021;83(4):1415-1429
Journal of Alzheimer's disease : JAD 2021;83(4):1415-1429
Gut Microbiota Disorders Promote Inflammation and Aggravate Spinal Cord Injury Through the TLR4/MyD88 Signaling Pathway.
Rong Z, Huang Y, Cai H, Chen M, Wang H, Liu G, Zhang Z, Wu J
Frontiers in nutrition 2021;8:702659
Frontiers in nutrition 2021;8:702659
NU9056, a KAT 5 Inhibitor, Treatment Alleviates Brain Dysfunction by Inhibiting NLRP3 Inflammasome Activation, Affecting Gut Microbiota, and Derived Metabolites in LPS-Treated Mice.
Chen L, Qing W, Yi Z, Lin G, Peng Q, Zhou F
Frontiers in nutrition 2021;8:701760
Frontiers in nutrition 2021;8:701760
Attenuation in Proinflammatory Factors and Reduction in Neuronal Cell Apoptosis and Cerebral Vasospasm by Minocycline during Early Phase after Subarachnoid Hemorrhage in the Rat.
Chung CL, Tsai HP, Huang YH, Wu SC, Chai CY, Kwan AL
BioMed research international 2021;2021:5545727
BioMed research international 2021;2021:5545727
Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood-brain barrier during kainic acid-induced brain damage.
Yu H, He B, Han X, Yan T
Open life sciences 2021;16(1):845-855
Open life sciences 2021;16(1):845-855
Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells.
Bodnar B, Zhang Y, Liu J, Lin Y, Wang P, Wei Z, Saribas S, Zhu Y, Li F, Wang X, Yang W, Li Q, Ho WZ, Hu W
Frontiers in cellular neuroscience 2021;15:682272
Frontiers in cellular neuroscience 2021;15:682272
Isoliquiritigenin Confers Neuroprotection and Alleviates Amyloid-β42-Induced Neuroinflammation in Microglia by Regulating the Nrf2/NF-κB Signaling.
Fu Y, Jia J
Frontiers in neuroscience 2021;15:638772
Frontiers in neuroscience 2021;15:638772
Class IIa HDAC Downregulation Contributes to Surgery-Induced Cognitive Impairment Through HMGB1-Mediated Inflammatory Response in the Hippocampi of Aged Mice.
Huang CM, Cai JJ, Jin SW, Lin QC, Fang QJ, Nan K, Han Y, Ge WW, Liu Y, Tao YX, Cao H, Li J
Journal of inflammation research 2021;14:2301-2315
Journal of inflammation research 2021;14:2301-2315
Edaravone Plays Protective Effects on LPS-Induced Microglia by Switching M1/M2 Phenotypes and Regulating NLRP3 Inflammasome Activation.
Li J, Dai X, Zhou L, Li X, Pan D
Frontiers in pharmacology 2021;12:691773
Frontiers in pharmacology 2021;12:691773
Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer's-Like Pathology in the Hippocampus by Altering the Phenotype of Microglia in the APP/PS1 Mouse Model.
Wu D, Kumal JPP, Lu X, Li Y, Mao D, Tang X, Nie M, Liu X, Sun L, Liu B, Zhang Y
Frontiers in neurology 2021;12:666430
Frontiers in neurology 2021;12:666430
Catalytic patch with redox Cr/CeO(2) nanozyme of noninvasive intervention for brain trauma.
Zhang S, Liu Y, Sun S, Wang J, Li Q, Yan R, Gao Y, Liu H, Liu S, Hao W, Dai H, Liu C, Sun Y, Long W, Mu X, Zhang XD
Theranostics 2021;11(6):2806-2821
Theranostics 2021;11(6):2806-2821
Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring.
Yang L, Dong Y, Wu C, Youngblood H, Li Y, Zong X, Li L, Xu T, Zhang Q
Theranostics 2021;11(3):1269-1294
Theranostics 2021;11(3):1269-1294
Hypoxia-preconditioned mesenchymal stem cells attenuate microglial pyroptosis after intracerebral hemorrhage.
Liu J, He J, Huang Y, Ge L, Xiao H, Zeng L, Jiang Z, Lu M, Hu Z
Annals of translational medicine 2021 Sep;9(17):1362
Annals of translational medicine 2021 Sep;9(17):1362
Edaravone attenuates cadmium-induced toxicity by inhibiting oxidative stress and inflammation in ICR mice.
Fan SR, Ren TT, Yun MY, Lan R, Qin XY
Neurotoxicology 2021 Sep;86:1-9
Neurotoxicology 2021 Sep;86:1-9
Nilotinib inhibits microglia-mediated neuroinflammation to protect against dopaminergic neuronal death in Parkinson's disease models.
Wu J, Xu X, Zheng L, Mo J, Jin X, Bao Y
International immunopharmacology 2021 Oct;99:108025
International immunopharmacology 2021 Oct;99:108025
Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats.
Xing C, Zhou Y, Xu H, Ding M, Zhang Y, Zhang M, Hu M, Huang X, Song L
Neuroscience research 2021 Oct;171:124-132
Neuroscience research 2021 Oct;171:124-132
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Lu Y, Hao R, Hu Y, Wei Y, Xie Y, Shen Y, Rui Q, Yu G
Chemico-biological interactions 2021 Oct 1;348:109653
Chemico-biological interactions 2021 Oct 1;348:109653
Bioinformatics analysis identifies CSF1R as an essential gene mediating Neuropathic pain - Experimental research.
Xu C, Zheng H, Liu T, Zhang Y, Feng Y
International journal of surgery (London, England) 2021 Nov;95:106140
International journal of surgery (London, England) 2021 Nov;95:106140
Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.
Hao W, Hao C, Wu C, Xu Y, Wu S, Lu X, Yang J, Jin C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112591
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112591
TC10, a Rho family GTPase, is required for efficient axon regeneration in a neuron-autonomous manner.
Koinuma S, Negishi R, Nomura R, Sato K, Kojima T, Segi-Nishida E, Goitsuka R, Iwakura Y, Wada N, Koriyama Y, Kiryu-Seo S, Kiyama H, Nakamura T
Journal of neurochemistry 2021 May;157(4):1196-1206
Journal of neurochemistry 2021 May;157(4):1196-1206
A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota.
Guo Y, Zhu X, Zeng M, Qi L, Tang X, Wang D, Zhang M, Xie Y, Li H, Yang X, Chen D
Translational psychiatry 2021 May 27;11(1):328
Translational psychiatry 2021 May 27;11(1):328
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
Wang D, Zhang H, Zeng M, Tang X, Zhu X, Guo Y, Qi L, Xie Y, Zhang M, Chen D
Aging 2021 Mar 26;13(7):10240-10274
Aging 2021 Mar 26;13(7):10240-10274
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Wu X, Sheng H, Wang L, Xia P, Wang Y, Yu L, Lv W, Hu J
Aging 2021 Mar 26;13(7):10034-10057
Aging 2021 Mar 26;13(7):10034-10057
Protective effects of melatonin on the white matter damage of neonatal rats by regulating NLRP3 inflammasome activity.
Qin M, Liu Y, Sun M, Li X, Xu J, Zhang L, Jiang H
Neuroreport 2021 Jun 9;32(9):739-747
Neuroreport 2021 Jun 9;32(9):739-747
Edaravone attenuates H(2)O(2) or glutamate-induced toxicity in hippocampal neurons and improves AlCl(3)/D-galactose induced cognitive impairment in mice.
Wu HT, Yu Y, Li XX, Lang XY, Gu RZ, Fan SR, Fang X, Bai JP, Lan R, Qin XY
Neurotoxicology 2021 Jul;85:68-78
Neurotoxicology 2021 Jul;85:68-78
Increased Expression of Thymic Stromal Lymphopoietin in Chronic Constriction Injury of Rat Nerve.
Wu CH, Lu CC, Huang CL, Wu MK, Lu YY
International journal of molecular sciences 2021 Jul 1;22(13)
International journal of molecular sciences 2021 Jul 1;22(13)
Minocycline alleviates depression-like symptoms by rescuing decrease in neurogenesis in dorsal hippocampus via blocking microglia activation/phagocytosis.
Bassett B, Subramaniyam S, Fan Y, Varney S, Pan H, Carneiro AMD, Chung CY
Brain, behavior, and immunity 2021 Jan;91:519-530
Brain, behavior, and immunity 2021 Jan;91:519-530
Role of lipocalin-2 in extracellular peroxiredoxin 2-induced brain swelling, inflammation and neuronal death.
Zhang J, Novakovic N, Hua Y, Keep RF, Xi G
Experimental neurology 2021 Jan;335:113521
Experimental neurology 2021 Jan;335:113521
Adrenomedullin 2 attenuates LPS-induced inflammation in microglia cells by receptor-mediated cAMP-PKA pathway.
Sun J, Qian P, Kang Y, Dai HB, Wang FZ, Wang HY, Zhou H, Gao Q, Zhou YB
Neuropeptides 2021 Feb;85:102109
Neuropeptides 2021 Feb;85:102109
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Wang C, Xu T, Lachance BB, Zhong X, Shen G, Xu T, Tang C, Jia X
Journal of neuroinflammation 2021 Feb 18;18(1):50
Journal of neuroinflammation 2021 Feb 18;18(1):50
Annexin A1 Attenuates Neutrophil Migration and IL-6 Expression through Fpr2 in a Mouse Model of Streptococcus suis-Induced Meningitis.
Ni C, Gao S, Zheng Y, Liu P, Zhai Y, Huang W, Jiang H, Lv Q, Kong D, Jiang Y
Infection and immunity 2021 Feb 16;89(3)
Infection and immunity 2021 Feb 16;89(3)
Gisenoside Rg1 attenuates cadmium-induced neurotoxicity in vitro and in vivo by attenuating oxidative stress and inflammation.
Ren TT, Yang JY, Wang J, Fan SR, Lan R, Qin XY
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2021 Dec;70(10-12):1151-1164
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2021 Dec;70(10-12):1151-1164
Schizandrin A ameliorates cognitive functions via modulating microglial polarisation in Alzheimer's disease mice.
Wang Q, Liu L, Guan H, Zhou Y, Li Q
Pharmaceutical biology 2021 Dec;59(1):860-867
Pharmaceutical biology 2021 Dec;59(1):860-867
Integration of Raman spectra with transcriptome data in glioblastoma multiforme defines tumour subtypes and predicts patient outcome.
Le Reste PJ, Pilalis E, Aubry M, McMahon M, Cano L, Etcheverry A, Chatziioannou A, Chevet E, Fautrel A
Journal of cellular and molecular medicine 2021 Dec;25(23):10846-10856
Journal of cellular and molecular medicine 2021 Dec;25(23):10846-10856
Comprehensive transcriptomic characterization reveals core genes and module associated with immunological changes via 1619 samples of brain glioma.
Zhang Y, Ma W, Fan W, Ren C, Xu J, Zeng F, Bao Z, Jiang T, Zhao Z
Cell death & disease 2021 Dec 8;12(12):1140
Cell death & disease 2021 Dec 8;12(12):1140
Axl Alleviates Neuroinflammation and Delays Japanese Encephalitis Progression in Mice.
Wang ZY, Zhen ZD, Fan DY, Wang PG, An J
Virologica Sinica 2021 Aug;36(4):667-677
Virologica Sinica 2021 Aug;36(4):667-677
8-Formylophiopogonanone B antagonizes doxorubicin-induced cardiotoxicity by suppressing heme oxygenase-1-dependent myocardial inflammation and fibrosis.
Qin D, Yue R, Deng P, Wang X, Zheng Z, Lv M, Zhang Y, Pu J, Xu J, Liang Y, Pi H, Yu Z, Hu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111779
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111779
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
Xia Y, Zhang G, Kou L, Yin S, Han C, Hu J, Wan F, Sun Y, Wu J, Li Y, Huang J, Xiong N, Zhang Z, Wang T
Brain : a journal of neurology 2021 Aug 17;144(7):2024-2037
Brain : a journal of neurology 2021 Aug 17;144(7):2024-2037
Phytogalactolipid dLGG Inhibits Mouse Melanoma Brain Metastasis through Regulating Oxylipin Activity and Re-Programming Macrophage Polarity in the Tumor Microenvironment.
Yang CC, Chang MT, Chang CK, Shyur LF
Cancers 2021 Aug 16;13(16)
Cancers 2021 Aug 16;13(16)
Phosphatase and Tensin Homolog Deleted on Chromosome Ten Knockdown Attenuates Cognitive Deficits by Inhibiting Neuroinflammation in a Mouse Model of Perioperative Neurocognitive Disorder.
Shen Y, Chen L, Zhang Y, Du J, Hu J, Bao H, Xing Y, Si Y
Neuroscience 2021 Aug 1;468:199-210
Neuroscience 2021 Aug 1;468:199-210
Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage.
Xu J, Duan Z, Qi X, Ou Y, Guo X, Zi L, Wei Y, Liu H, Ma L, Li H, You C, Tian M
Frontiers in bioengineering and biotechnology 2020;8:785
Frontiers in bioengineering and biotechnology 2020;8:785
Microglia TREM2: A Potential Role in the Mechanism of Action of Electroacupuncture in an Alzheimer's Disease Animal Model.
Li Y, Jiang J, Tang Q, Tian H, Wang S, Wang Z, Liu H, Yang J, Ren J
Neural plasticity 2020;2020:8867547
Neural plasticity 2020;2020:8867547
Nrf2 Ablation Promotes Alzheimer's Disease-Like Pathology in APP/PS1 Transgenic Mice: The Role of Neuroinflammation and Oxidative Stress.
Ren P, Chen J, Li B, Zhang M, Yang B, Guo X, Chen Z, Cheng H, Wang P, Wang S, Wang N, Zhang G, Wu X, Ma D, Guan D, Zhao R
Oxidative medicine and cellular longevity 2020;2020:3050971
Oxidative medicine and cellular longevity 2020;2020:3050971
Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia.
He XM, Zhou YZ, Sheng S, Li JJ, Wang GQ, Zhang F
Oxidative medicine and cellular longevity 2020;2020:2963540
Oxidative medicine and cellular longevity 2020;2020:2963540
Resveratrol Preincubation Enhances the Therapeutic Efficacy of hUC-MSCs by Improving Cell Migration and Modulating Neuroinflammation Mediated by MAPK Signaling in a Mouse Model of Alzheimer's Disease.
Wang X, Wu J, Ma S, Xie Y, Liu H, Yao M, Zhang Y, Yang GL, Yang B, Guo R, Guan F
Frontiers in cellular neuroscience 2020;14:62
Frontiers in cellular neuroscience 2020;14:62
Bloodletting Puncture at Hand Twelve Jing-Well Points Improves Neurological Recovery by Ameliorating Acute Traumatic Brain Injury-Induced Coagulopathy in Mice.
Li B, Zhou X, Yi TL, Xu ZW, Peng DW, Guo Y, Guo YM, Cao YL, Zhu L, Zhang S, Cheng SX
Frontiers in neuroscience 2020;14:403
Frontiers in neuroscience 2020;14:403
Kalirin-7 contributes to type 2 diabetic neuropathic pain via the postsynaptic density-95/N-methyl-D-aspartate receptor 2B-dependent N-methyl-D-aspartate receptor 2B phosphorylation in the spinal cord in rats.
Lu JH, Zhang MB, Wang JW, Ye XY, Chen JL, Jia GL, Xie CS, Shen YJ, Tao YX, Li J, Cao H
American journal of translational research 2020;12(8):4819-4829
American journal of translational research 2020;12(8):4819-4829
Caveolin-1 in spinal cord modulates type-2 diabetic neuropathic pain through the Rac1/NOX2/NR2B signaling pathway.
Chen JL, Lu JH, Xie CS, Shen YJ, Wang JW, Ye XY, Zhang MB, Jia GL, Tao YX, Li J, Cao H
American journal of translational research 2020;12(5):1714-1727
American journal of translational research 2020;12(5):1714-1727
FTY720 Prevents Spatial Memory Impairment in a Rat Model of Chronic Cerebral Hypoperfusion via a SIRT3-Independent Pathway.
Zhang M, Hu Y, Zhang J, Zhang J
Frontiers in aging neuroscience 2020;12:593364
Frontiers in aging neuroscience 2020;12:593364
LongShengZhi Capsule Attenuates Alzheimer-Like Pathology in APP/PS1 Double Transgenic Mice by Reducing Neuronal Oxidative Stress and Inflammation.
Yin Z, Wang X, Zheng S, Cao P, Chen Y, Yu M, Liao C, Zhang Z, Han J, Duan Y, Yang X, Zhang S
Frontiers in aging neuroscience 2020;12:582455
Frontiers in aging neuroscience 2020;12:582455
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Yu Y, Wu DM, Li J, Deng SH, Liu T, Zhang T, He M, Zhao YY, Xu Y
Frontiers in immunology 2020;11:593368
Frontiers in immunology 2020;11:593368
Glucagon-like peptide-1 receptor agonist Exendin-4 improves neurological outcomes by attenuating TBI- induced inflammatory responses and MAPK activation in rats.
Zhang J, Yi T, Cheng S, Zhang S
International immunopharmacology 2020 Sep;86:106715
International immunopharmacology 2020 Sep;86:106715
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat.
Chen Y, Li J, Ma B, Li N, Wang S, Sun Z, Xue C, Han Q, Wei J, Zhao RC
Aging 2020 Sep 23;12(18):18274-18296
Aging 2020 Sep 23;12(18):18274-18296
MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis.
Ma S, Wang Y, Zhou X, Li Z, Zhang Z, Wang Y, Huang T, Zhang Y, Shi J, Guan F
ACS chemical neuroscience 2020 Sep 2;11(17):2590-2601
ACS chemical neuroscience 2020 Sep 2;11(17):2590-2601
Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain.
Zajaczkowska R, Kwiatkowski K, Pawlik K, Piotrowska A, Rojewska E, Makuch W, Wordliczek J, Mika J
Pharmacological reports : PR 2020 Oct;72(5):1310-1322
Pharmacological reports : PR 2020 Oct;72(5):1310-1322
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage.
Xiong Y, Xin DQ, Hu Q, Wang LX, Qiu J, Yuan HT, Chu XL, Liu DX, Li G, Wang Z
Neural regeneration research 2020 Oct;15(10):1920-1930
Neural regeneration research 2020 Oct;15(10):1920-1930
IL-1β/IL-1R1 signaling induced by intranasal lipopolysaccharide infusion regulates alpha-Synuclein pathology in the olfactory bulb, substantia nigra and striatum.
Niu H, Wang Q, Zhao W, Liu J, Wang D, Muhammad B, Liu X, Quan N, Zhang H, Zhang F, Wang Y, Li H, Yang R
Brain pathology (Zurich, Switzerland) 2020 Nov;30(6):1102-1118
Brain pathology (Zurich, Switzerland) 2020 Nov;30(6):1102-1118
Morphological analyzes of microglia heterogeneity and dynamics during photoreceptor degeneration in vitro: Presumptive dark microglia in porcine retina.
Johansson K, Svensson LA, Mohlin C
Experimental eye research 2020 Nov;200:108217
Experimental eye research 2020 Nov;200:108217
Attenuation of Acute Intracerebral Hemorrhage-Induced Microglial Activation and Neuronal Death Mediated by the Blockade of Metabotropic Glutamate Receptor 5 In Vivo.
Rahman MS, Yang J, Luan Y, Qiu Z, Zhang J, Lu H, Chen X, Liu Y
Neurochemical research 2020 May;45(5):1230-1243
Neurochemical research 2020 May;45(5):1230-1243
Changes in macrophage inflammatory protein-1 (MIP-1) family members expression induced by traumatic brain injury in mice.
Ciechanowska A, Popiolek-Barczyk K, Pawlik K, Ciapała K, Oggioni M, Mercurio D, De Simoni MG, Mika J
Immunobiology 2020 May;225(3):151911
Immunobiology 2020 May;225(3):151911
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Hou B, Zhang Y, Liang P, He Y, Peng B, Liu W, Han S, Yin J, He X
Cell death & disease 2020 May 15;11(5):377
Cell death & disease 2020 May 15;11(5):377
Carbon dot targeting to nitrogen signaling molecules for inhibiting neuronal death.
Ouyang L, Mu X, Wang J, Li Q, Gao Y, Liu H, Sun S, Ren Q, Yan R, Wang J, Liu Q, Sun Y, Liu C, He H, Long W, Zhang XD
Journal of materials chemistry. B 2020 Mar 18;8(11):2321-2330
Journal of materials chemistry. B 2020 Mar 18;8(11):2321-2330
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
Zong X, Dong Y, Li Y, Yang L, Li Y, Yang B, Tucker L, Zhao N, Brann DW, Yan X, Hu S, Zhang Q
Translational stroke research 2020 Jun;11(3):450-467
Translational stroke research 2020 Jun;11(3):450-467
The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression.
Wang X, Yang J, Lu T, Zhan Z, Wei W, Lyu X, Jiang Y, Xue X
Aging 2020 Jun 9;12(11):11085-11099
Aging 2020 Jun 9;12(11):11085-11099
Natural Xanthone α-Mangostin Inhibits LPS-Induced Microglial Inflammatory Responses and Memory Impairment by Blocking the TAK1/NF-κB Signaling Pathway.
Guan H, Li J, Tan X, Luo S, Liu Y, Meng Y, Wu B, Zhou Y, Yang Y, Chen H, Hou L, Qiu Y, Li J
Molecular nutrition & food research 2020 Jul;64(14):e2000096
Molecular nutrition & food research 2020 Jul;64(14):e2000096
Effects of Exercise Training on Anxious-Depressive-like Behavior in Alzheimer Rat.
Wu C, Yang L, Li Y, Dong Y, Yang B, Tucker LD, Zong X, Zhang Q
Medicine and science in sports and exercise 2020 Jul;52(7):1456-1469
Medicine and science in sports and exercise 2020 Jul;52(7):1456-1469
Over-Expression of Allograft Inflammatory Factor-1 (AIF-1) in Patients with Rheumatoid Arthritis.
Piotrowska K, Słuczanowska-Głabowska S, Kurzawski M, Dziedziejko V, Kopytko P, Paczkowska E, Rogińska D, Safranow K, Machaliński B, Pawlik A
Biomolecules 2020 Jul 16;10(7)
Biomolecules 2020 Jul 16;10(7)
Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage.
Guo F, Xu D, Lin Y, Wang G, Wang F, Gao Q, Wei Q, Lei S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1872-1884
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1872-1884
BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease.
Wu Y, Gong Y, Luan Y, Li Y, Liu J, Yue Z, Yuan B, Sun J, Xie C, Li L, Zhen J, Jin X, Zheng Y, Wang X, Xie L, Wang W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1412-1429
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1412-1429
Synaptic alterations and immune response are sexually dimorphic in a non-pertussis toxin model of experimental autoimmune encephalomyelitis.
Murphy KL, Fischer R, Swanson KA, Bhatt IJ, Oakley L, Smeyne R, Bracchi-Ricard V, Bethea JR
Experimental neurology 2020 Jan;323:113061
Experimental neurology 2020 Jan;323:113061
Scorpion alleviates bone cancer pain through inhibition of bone destruction and glia activation.
Yu J, Luo Y, Jin H, Lv J, Zhou T, Yabasin IB, Wen Q
Molecular pain 2020 Jan-Dec;16:1744806920909993
Molecular pain 2020 Jan-Dec;16:1744806920909993
Protective role of cinnabar and realgar in Hua-Feng-Dan against LPS plus rotenone-induced neurotoxicity and disturbance of gut microbiota in rats.
Chen C, Zhang BB, Hu AL, Li H, Liu J, Zhang F
Journal of ethnopharmacology 2020 Jan 30;247:112299
Journal of ethnopharmacology 2020 Jan 30;247:112299
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Xu B, Lang LM, Lian S, Guo JR, Wang JF, Liu J, Yang HM, Li SZ
Brain research 2020 Jan 1;1726:146495
Brain research 2020 Jan 1;1726:146495
Photobiomodulation therapy for repeated closed head injury in rats.
Yang B, Xu J, Li Y, Dong Y, Li Y, Tucker L, Yang L, Zong X, Wu C, Xu T, Hu S, Zhang Q, Yan X
Journal of biophotonics 2020 Feb;13(2):e201960117
Journal of biophotonics 2020 Feb;13(2):e201960117
Acetate attenuates perioperative neurocognitive disorders in aged mice.
Wen C, Xie T, Pan K, Deng Y, Zhao Z, Li N, Bian J, Deng X, Zha Y
Aging 2020 Feb 26;12(4):3862-3879
Aging 2020 Feb 26;12(4):3862-3879
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Lang L, Xu B, Yuan J, Li S, Lian S, Chen Y, Guo J, Yang H
International immunopharmacology 2020 Dec;89(Pt B):106908
International immunopharmacology 2020 Dec;89(Pt B):106908
Menthol protects dopaminergic neurons against inflammation-mediated damage in lipopolysaccharide (LPS)-Evoked model of Parkinson's disease.
Du J, Liu D, Zhang X, Zhou A, Su Y, He D, Fu S, Gao F
International immunopharmacology 2020 Aug;85:106679
International immunopharmacology 2020 Aug;85:106679
Glutathione Depletion and Parkinsonian Neurotoxin MPP(+)-Induced TRPM2 Channel Activation Play Central Roles in Oxidative Cytotoxicity and Inflammation in Microglia.
Yıldızhan K, Nazıroğlu M
Molecular neurobiology 2020 Aug;57(8):3508-3525
Molecular neurobiology 2020 Aug;57(8):3508-3525
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
Fan X, Elkin K, Shi Y, Zhang Z, Cheng Y, Gu J, Liang J, Wang C, Ji X
Neurological research 2020 Aug;42(8):693-702
Neurological research 2020 Aug;42(8):693-702
CCR4 antagonist (C021) influences the level of nociceptive factors and enhances the analgesic potency of morphine in a rat model of neuropathic pain.
Bogacka J, Popiolek-Barczyk K, Pawlik K, Ciechanowska A, Makuch W, Rojewska E, Dobrogowski J, Przeklasa-Muszynska A, Mika J
European journal of pharmacology 2020 Aug 5;880:173166
European journal of pharmacology 2020 Aug 5;880:173166
Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages.
Wang ZY, Zhen ZD, Fan DY, Qin CF, Han DS, Zhou HN, Wang PG, An J
Journal of virology 2020 Aug 17;94(17)
Journal of virology 2020 Aug 17;94(17)
Cu(II) disrupts autophagy-mediated lysosomal degradation of oligomeric Aβ in microglia via mTOR-TFEB pathway.
Tan X, Guan H, Yang Y, Luo S, Hou L, Chen H, Li J
Toxicology and applied pharmacology 2020 Aug 15;401:115090
Toxicology and applied pharmacology 2020 Aug 15;401:115090
Mefenamic acid can attenuate depressive symptoms by suppressing microglia activation induced upon chronic stress.
Feng X, Fan Y, Chung CY
Brain research 2020 Aug 1;1740:146846
Brain research 2020 Aug 1;1740:146846
Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation.
Wu Z, Zhang Y, Zhang Y, Zhao P
Cellular and molecular neurobiology 2020 Apr;40(3):437-446
Cellular and molecular neurobiology 2020 Apr;40(3):437-446
The blockade of CC chemokine receptor type 1 influences the level of nociceptive factors and enhances opioid analgesic potency in a rat model of neuropathic pain.
Pawlik K, Piotrowska A, Kwiatkowski K, Ciapała K, Popiolek-Barczyk K, Makuch W, Mika J
Immunology 2020 Apr;159(4):413-428
Immunology 2020 Apr;159(4):413-428
Intracerebral Hemorrhage-Induced Brain Injury in Rats: the Role of Extracellular Peroxiredoxin 2.
Bian L, Zhang J, Wang M, Keep RF, Xi G, Hua Y
Translational stroke research 2020 Apr;11(2):288-295
Translational stroke research 2020 Apr;11(2):288-295
Interferon-λ Attenuates Rabies Virus Infection by Inducing Interferon-Stimulated Genes and Alleviating Neurological Inflammation.
Li Y, Zhao L, Luo Z, Zhang Y, Lv L, Zhao J, Sui B, Huang F, Cui M, Fu ZF, Zhou M
Viruses 2020 Apr 6;12(4)
Viruses 2020 Apr 6;12(4)
[Establishment of a vimentin knockout and HIV-1 gp120 transgenic mouse model].
He X, Peng L, Zhang B, Li L, Wu C, Xiao H, Yang W, Zeng Z, Yang X, Long M, Cao H, Huang S
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2020 Apr 30;40(4):519-524
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2020 Apr 30;40(4):519-524
H(2)S attenuates injury after ischemic stroke by diminishing the assembly of CaMKII with ASK1-MKK3-p38 signaling module.
Song YJ, Shi Y, Cui MM, Li M, Wen XR, Zhou XY, Lou HQ, Wang YL, Qi DS, Tang M, Zhang XB
Behavioural brain research 2020 Apr 20;384:112520
Behavioural brain research 2020 Apr 20;384:112520
Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury.
Zhao C, Zhou X, Qiu J, Xin D, Li T, Chu X, Yuan H, Wang H, Wang Z, Wang D
Drug design, development and therapy 2019;13:3693-3704
Drug design, development and therapy 2019;13:3693-3704
Expression of cysteinyl leukotriene receptor in brain tissues of rats with Streptococcus pneumoniae meningitis.
Yu S, Yan J, Chen X, Zhu X, Li X, Liao L
International journal of clinical and experimental pathology 2019;12(12):4242-4252
International journal of clinical and experimental pathology 2019;12(12):4242-4252
Naringenin Produces Neuroprotection Against LPS-Induced Dopamine Neurotoxicity via the Inhibition of Microglial NLRP3 Inflammasome Activation.
Chen C, Wei YZ, He XM, Li DD, Wang GQ, Li JJ, Zhang F
Frontiers in immunology 2019;10:936
Frontiers in immunology 2019;10:936
Pharmacological Blockade of Spinal CXCL3/CXCR2 Signaling by NVP CXCR2 20, a Selective CXCR2 Antagonist, Reduces Neuropathic Pain Following Peripheral Nerve Injury.
Piotrowska A, Rojewska E, Pawlik K, Kreiner G, Ciechanowska A, Makuch W, Nalepa I, Mika J
Frontiers in immunology 2019;10:2198
Frontiers in immunology 2019;10:2198
Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis.
Liu F, Li Z, He X, Yu H, Feng J
Frontiers in pharmacology 2019;10:1320
Frontiers in pharmacology 2019;10:1320
Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet.
Xu J, Gao H, Zhang L, Rong S, Yang W, Ma C, Chen M, Huang Q, Deng Q, Huang F
Journal of pineal research 2019 Sep;67(2):e12584
Journal of pineal research 2019 Sep;67(2):e12584
Intracerebroventricular administration of lupus serum induces microglia activation and leukocyte adhesion in the cerebromicrovasculature of mice.
Wang X, Li Y, Wang Y, Feng Q, Yang P, Qin L
Journal of neuroimmunology 2019 Sep 15;334:576994
Journal of neuroimmunology 2019 Sep 15;334:576994
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhang G, Liu N, Zhu C, Ma L, Yang J, Du J, Zhang W, Sun T, Niu J, Yu J
International immunopharmacology 2019 Oct;75:105753
International immunopharmacology 2019 Oct;75:105753
Farrerol protects dopaminergic neurons in a rat model of lipopolysaccharide-induced Parkinson's disease by suppressing the activation of the AKT and NF-κB signaling pathways.
Li Y, Zeng Y, Meng T, Gao X, Huang B, He D, Ran X, Du J, Zhang Y, Fu S, Hu G
International immunopharmacology 2019 Oct;75:105739
International immunopharmacology 2019 Oct;75:105739
Nanozyme-Based Bandage with Single-Atom Catalysis for Brain Trauma.
Yan R, Sun S, Yang J, Long W, Wang J, Mu X, Li Q, Hao W, Zhang S, Liu H, Gao Y, Ouyang L, Chen J, Liu S, Zhang XD, Ming D
ACS nano 2019 Oct 22;13(10):11552-11560
ACS nano 2019 Oct 22;13(10):11552-11560
TREM2 deficiency aggravates α-synuclein-induced neurodegeneration and neuroinflammation in Parkinson's disease models.
Guo Y, Wei X, Yan H, Qin Y, Yan S, Liu J, Zhao Y, Jiang F, Lou H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12164-12174
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12164-12174
Splicing repression is a major function of TDP-43 in motor neurons.
Donde A, Sun M, Ling JP, Braunstein KE, Pang B, Wen X, Cheng X, Chen L, Wong PC
Acta neuropathologica 2019 Nov;138(5):813-826
Acta neuropathologica 2019 Nov;138(5):813-826
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Ma B, Cheng H, Mu C, Geng G, Zhao T, Luo Q, Ma K, Chang R, Liu Q, Gao R, Nie J, Xie J, Han J, Chen L, Ma G, Zhu Y, Chen Q
Nature communications 2019 Mar 4;10(1):1034
Nature communications 2019 Mar 4;10(1):1034
Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1.
Yousef H, Czupalla CJ, Lee D, Chen MB, Burke AN, Zera KA, Zandstra J, Berber E, Lehallier B, Mathur V, Nair RV, Bonanno LN, Yang AC, Peterson T, Hadeiba H, Merkel T, Körbelin J, Schwaninger M, Buckwalter MS, Quake SR, Butcher EC, Wyss-Coray T
Nature medicine 2019 Jun;25(6):988-1000
Nature medicine 2019 Jun;25(6):988-1000
Complement Inhibition Attenuates Early Erythrolysis in the Hematoma and Brain Injury in Aged Rats.
Wang M, Hua Y, Keep RF, Wan S, Novakovic N, Xi G
Stroke 2019 Jul;50(7):1859-1868
Stroke 2019 Jul;50(7):1859-1868
Naringenin targets on astroglial Nrf2 to support dopaminergic neurons.
Wang GQ, Zhang B, He XM, Li DD, Shi JS, Zhang F
Pharmacological research 2019 Jan;139:452-459
Pharmacological research 2019 Jan;139:452-459
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Zhu BL, Long Y, Luo W, Yan Z, Lai YJ, Zhao LG, Zhou WH, Wang YJ, Shen LL, Liu L, Deng XJ, Wang XF, Sun F, Chen GJ
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Xu B, Zang SC, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM, Lian S
Brain, behavior, and immunity 2019 Feb;76:223-235
Brain, behavior, and immunity 2019 Feb;76:223-235
Redox Trimetallic Nanozyme with Neutral Environment Preference for Brain Injury.
Mu X, Wang J, Li Y, Xu F, Long W, Ouyang L, Liu H, Jing Y, Wang J, Dai H, Liu Q, Sun Y, Liu C, Zhang XD
ACS nano 2019 Feb 26;13(2):1870-1884
ACS nano 2019 Feb 26;13(2):1870-1884
Microglia as modulators of exosomal alpha-synuclein transmission.
Xia Y, Zhang G, Han C, Ma K, Guo X, Wan F, Kou L, Yin S, Liu L, Huang J, Xiong N, Wang T
Cell death & disease 2019 Feb 20;10(3):174
Cell death & disease 2019 Feb 20;10(3):174
Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway.
Wang J, Jiang C, Zhang K, Lan X, Chen X, Zang W, Wang Z, Guan F, Zhu C, Yang X, Lu H, Wang J
Free radical biology & medicine 2019 Feb 1;131:345-355
Free radical biology & medicine 2019 Feb 1;131:345-355
Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor.
Yang C, Hou X, Feng Q, Li Y, Wang X, Qin L, Yang P
Journal of translational medicine 2019 Dec 21;17(1):426
Journal of translational medicine 2019 Dec 21;17(1):426
MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo.
Guan F, Zhou X, Li P, Wang Y, Liu M, Li F, Cui Y, Huang T, Yao M, Zhang Y, Ma J, Ma S
Progress in neuro-psychopharmacology & biological psychiatry 2019 Dec 20;95:109684
Progress in neuro-psychopharmacology & biological psychiatry 2019 Dec 20;95:109684
Maternal separation disturbs postnatal development of the medial prefrontal cortex and affects the number of neurons and glial cells in adolescent rats.
Majcher-Maślanka I, Solarz A, Chocyk A
Neuroscience 2019 Dec 15;423:131-147
Neuroscience 2019 Dec 15;423:131-147
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Xu B, Lang LM, Li SZ, Guo JR, Wang JF, Yang HM, Lian S
Biomolecules 2019 Aug 30;9(9)
Biomolecules 2019 Aug 30;9(9)
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Zhang B, Wang G, He J, Yang Q, Li D, Li J, Zhang F
Journal of neuroinflammation 2019 Apr 22;16(1):92
Journal of neuroinflammation 2019 Apr 22;16(1):92
Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats.
Fan J, Chen M, Wang X, Tian Z, Wang J, Fan D, Zeng J, Zhang K, Dai X
Toxicological sciences : an official journal of the Society of Toxicology 2019 Apr 1;168(2):381-393
Toxicological sciences : an official journal of the Society of Toxicology 2019 Apr 1;168(2):381-393
Involvement of Macrophage Inflammatory Protein-1 Family Members in the Development of Diabetic Neuropathy and Their Contribution to Effectiveness of Morphine.
Rojewska E, Zychowska M, Piotrowska A, Kreiner G, Nalepa I, Mika J
Frontiers in immunology 2018;9:494
Frontiers in immunology 2018;9:494
Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3β-Nrf2/NF-κB Signaling Axis.
Huang B, Liu J, Meng T, Li Y, He D, Ran X, Chen G, Guo W, Kan X, Fu S, Wang W, Liu D
Frontiers in immunology 2018;9:2527
Frontiers in immunology 2018;9:2527
Allograft Inflammatory Factor-1 Mediates Macrophage-Induced Impairment of Insulin Signaling in Adipocytes.
Ren J, Lin Y, Tang J, Yue H, Zhao Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):403-413
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):403-413
Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures.
Zhang B, Wei YZ, Wang GQ, Li DD, Shi JS, Zhang F
Frontiers in cellular neuroscience 2018;12:531
Frontiers in cellular neuroscience 2018;12:531
Differential Regulation of Adhesion and Phagocytosis of Resting and Activated Microglia by Dopamine.
Fan Y, Chen Z, Pathak JL, Carneiro AMD, Chung CY
Frontiers in cellular neuroscience 2018;12:309
Frontiers in cellular neuroscience 2018;12:309
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Zuo Y, Wang J, Liao F, Yan X, Li J, Huang L, Liu F
Frontiers in molecular neuroscience 2018;11:401
Frontiers in molecular neuroscience 2018;11:401
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Xu B, Lian S, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM
Brain research bulletin 2018 Sep;142:163-175
Brain research bulletin 2018 Sep;142:163-175
Meloxicam Improves Cognitive Impairment of Diabetic Rats through COX2-PGE2-EPs-cAMP/pPKA Pathway.
Li H, Luo Y, Xu Y, Yang L, Hu C, Chen Q, Yang Y, Ma J, Zhang J, Xia H, Li Y, Yang J
Molecular pharmaceutics 2018 Sep 4;15(9):4121-4131
Molecular pharmaceutics 2018 Sep 4;15(9):4121-4131
Pharmacological blockade of CXCR3 by (±)-NBI-74330 reduces neuropathic pain and enhances opioid effectiveness - Evidence from in vivo and in vitro studies.
Piotrowska A, Rojewska E, Pawlik K, Kreiner G, Ciechanowska A, Makuch W, Zychowska M, Mika J
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3418-3437
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3418-3437
Zaprinast diminished pain and enhanced opioid analgesia in a rat neuropathic pain model.
Rojewska E, Piotrowska A, Jurga A, Makuch W, Mika J
European journal of pharmacology 2018 Nov 15;839:21-32
European journal of pharmacology 2018 Nov 15;839:21-32
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
Wu C, Yang L, Tucker D, Dong Y, Zhu L, Duan R, Liu TC, Zhang Q
Medicine and science in sports and exercise 2018 May;50(5):945-956
Medicine and science in sports and exercise 2018 May;50(5):945-956
[Role of allograft inflammatory factor-1 in regulating the proliferation, migration and apoptosis of colorectal cancer cells].
Ai XL, Yao F, Wang XJ, Duan DB, Li K, Hu ZY, Yin G, Wang M, Wu BY
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2018 May 20;38(5):511-519
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2018 May 20;38(5):511-519
Combination Treatment with Methylene Blue and Hypothermia in Global Cerebral Ischemia.
Li L, Yang R, Li P, Lu H, Hao J, Li L, Tucker D, Zhang Q
Molecular neurobiology 2018 Mar;55(3):2042-2055
Molecular neurobiology 2018 Mar;55(3):2042-2055
A model to study complement involvement in experimental retinal degeneration.
Mohlin C, Sandholm K, Kvanta A, Ekdahl KN, Johansson K
Upsala journal of medical sciences 2018 Mar;123(1):28-42
Upsala journal of medical sciences 2018 Mar;123(1):28-42
CD4+ αβ T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries.
Du B, Ding YQ, Xiao X, Ren HY, Su BY, Qi JG
Journal of neuroinflammation 2018 Mar 15;15(1):81
Journal of neuroinflammation 2018 Mar 15;15(1):81
Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways.
Chen G, Liu J, Jiang L, Ran X, He D, Li Y, Huang B, Wang W, Liu D, Fu S
International journal of molecular sciences 2018 Mar 12;19(3)
International journal of molecular sciences 2018 Mar 12;19(3)
Early Postnatal Exposure to Airborne Fine Particulate Matter Induces Autism-like Phenotypes in Male Rats.
Li K, Li L, Cui B, Gai Z, Li Q, Wang S, Yan J, Lin B, Tian L, Liu H, Liu X, Xi Z
Toxicological sciences : an official journal of the Society of Toxicology 2018 Mar 1;162(1):189-199
Toxicological sciences : an official journal of the Society of Toxicology 2018 Mar 1;162(1):189-199
Notch Signaling Regulates Microglial Activation and Inflammatory Reactions in a Rat Model of Temporal Lobe Epilepsy.
Wu L, Li Y, Yu M, Yang F, Tu M, Xu H
Neurochemical research 2018 Jun;43(6):1269-1282
Neurochemical research 2018 Jun;43(6):1269-1282
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Zhang J, Tucker LD, DongYan, Lu Y, Yang L, Wu C, Li Y, Zhang Q
Neurochemistry international 2018 Jun;116:1-12
Neurochemistry international 2018 Jun;116:1-12
Glia maturation factor beta is required for reactive gliosis after traumatic brain injury in zebrafish.
Yin G, Du M, Li R, Li K, Huang X, Duan D, Ai X, Yao F, Zhang L, Hu Z, Wu B
Experimental neurology 2018 Jul;305:129-138
Experimental neurology 2018 Jul;305:129-138
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis.
Nagahara H, Seno T, Yamamoto A, Obayashi H, Inoue T, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y
Biochemical and biophysical research communications 2018 Jan 8;495(2):1901-1907
Biochemical and biophysical research communications 2018 Jan 8;495(2):1901-1907
Lipopolysaccharide from Rhodobacter sphaeroides (TLR4 antagonist) attenuates hypersensitivity and modulates nociceptive factors.
Jurga AM, Rojewska E, Makuch W, Mika J
Pharmaceutical biology 2018 Dec;56(1):275-286
Pharmaceutical biology 2018 Dec;56(1):275-286
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Wang B, Zhang G, Yang M, Liu N, Li YX, Ma H, Ma L, Sun T, Tan H, Yu J
Neurochemical research 2018 Dec;43(12):2404-2422
Neurochemical research 2018 Dec;43(12):2404-2422
Involvement of microglial cells in the antinociceptive effects of metamizol in a mouse model of neuropathic pain.
Zajaczkowska R, Popiolek-Barczyk K, Pilat D, Rojewska E, Makuch W, Wordliczek J, Mika J
Pharmacology, biochemistry, and behavior 2018 Dec;175:77-88
Pharmacology, biochemistry, and behavior 2018 Dec;175:77-88
Upregulation of allograft inflammatory factor‑1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype.
Li Y, Wang X, Zhang L, Yuan X, Hao J, Ni J, Hao L
International journal of molecular medicine 2018 Aug;42(2):861-872
International journal of molecular medicine 2018 Aug;42(2):861-872
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
Zhang D, Sun X, Ren L, Yang C, Liu X, Zhang H, Jiang Y, Hu X
Journal of proteomics 2018 Aug 30;186:28-37
Journal of proteomics 2018 Aug 30;186:28-37
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
Cheng L, Chen L, Wei X, Wang Y, Ren Z, Zeng S, Zhang X, Wen H, Gao C, Liu H
Journal of neuroinflammation 2018 Aug 29;15(1):243
Journal of neuroinflammation 2018 Aug 29;15(1):243
Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model.
Jurga AM, Piotrowska A, Makuch W, Przewlocka B, Mika J
Frontiers in pharmacology 2017;8:48
Frontiers in pharmacology 2017;8:48
Colony-stimulating factor-1-induced AIF1 expression in tumor-associated macrophages enhances the progression of hepatocellular carcinoma.
Cai H, Zhu XD, Ao JY, Ye BG, Zhang YY, Chai ZT, Wang CH, Shi WK, Cao MQ, Li XL, Sun HC
Oncoimmunology 2017;6(9):e1333213
Oncoimmunology 2017;6(9):e1333213
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Lu Y, Dong Y, Tucker D, Wang R, Ahmed ME, Brann D, Zhang Q
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484
Ketamine Alleviates Depressive-Like Behaviors via Down-Regulating Inflammatory Cytokines Induced by Chronic Restraint Stress in Mice.
Tan S, Wang Y, Chen K, Long Z, Zou J
Biological & pharmaceutical bulletin 2017;40(8):1260-1267
Biological & pharmaceutical bulletin 2017;40(8):1260-1267
Intranasal Delivery of a Caspase-1 Inhibitor in the Treatment of Global Cerebral Ischemia.
Zhao N, Zhuo X, Lu Y, Dong Y, Ahmed ME, Tucker D, Scott EL, Zhang Q
Molecular neurobiology 2017 Sep;54(7):4936-4952
Molecular neurobiology 2017 Sep;54(7):4936-4952
The RS504393 Influences the Level of Nociceptive Factors and Enhances Opioid Analgesic Potency in Neuropathic Rats.
Kwiatkowski K, Piotrowska A, Rojewska E, Makuch W, Mika J
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2017 Sep;12(3):402-419
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2017 Sep;12(3):402-419
Licochalcone A Prevents the Loss of Dopaminergic Neurons by Inhibiting Microglial Activation in Lipopolysaccharide (LPS)-Induced Parkinson's Disease Models.
Huang B, Liu J, Ju C, Yang D, Chen G, Xu S, Zeng Y, Yan X, Wang W, Liu D, Fu S
International journal of molecular sciences 2017 Sep 22;18(10)
International journal of molecular sciences 2017 Sep 22;18(10)
Spinal CCL1/CCR8 signaling interplay as a potential therapeutic target - Evidence from a mouse diabetic neuropathy model.
Zychowska M, Rojewska E, Piotrowska A, Kreiner G, Nalepa I, Mika J
International immunopharmacology 2017 Nov;52:261-271
International immunopharmacology 2017 Nov;52:261-271
Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.
Zhang W, Xiao D, Shan L, Zhao J, Mao Q, Xia H
Biotechnology and bioengineering 2017 Nov;114(11):2539-2549
Biotechnology and bioengineering 2017 Nov;114(11):2539-2549
Silk fibroin-Pellethane® cardiovascular patches: Effect of silk fibroin concentration on vascular remodeling in rat model.
Chantawong P, Tanaka T, Uemura A, Shimada K, Higuchi A, Tajiri H, Sakura K, Murakami T, Nakazawa Y, Tanaka R
Journal of materials science. Materials in medicine 2017 Nov 14;28(12):191
Journal of materials science. Materials in medicine 2017 Nov 14;28(12):191
Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat.
Liu F, Wang Z, Qiu Y, Wei M, Li C, Xie Y, Shen L, Huang Y, Ma C
Journal of neuroinflammation 2017 Mar 31;14(1):70
Journal of neuroinflammation 2017 Mar 31;14(1):70
Fingolimod (FTY720) attenuates social deficits, learning and memory impairments, neuronal loss and neuroinflammation in the rat model of autism.
Wu H, Wang X, Gao J, Liang S, Hao Y, Sun C, Xia W, Cao Y, Wu L
Life sciences 2017 Mar 15;173:43-54
Life sciences 2017 Mar 15;173:43-54
Antibody incubation at 37°C improves fluorescent immunolabeling in free-floating thick tissue sections.
Xiao X, Feng YP, Du B, Sun HR, Ding YQ, Qi JG
BioTechniques 2017 Mar 1;62(3):115-122
BioTechniques 2017 Mar 1;62(3):115-122
Sarsasapogenin-AA13 ameliorates Aβ-induced cognitive deficits via improving neuroglial capacity on Aβ clearance and antiinflammation.
Huang C, Dong D, Jiao Q, Pan H, Ma L, Wang R
CNS neuroscience & therapeutics 2017 Jun;23(6):498-509
CNS neuroscience & therapeutics 2017 Jun;23(6):498-509
Adenosine production by brain cells.
Jackson EK, Kotermanski SE, Menshikova EV, Dubey RK, Jackson TC, Kochanek PM
Journal of neurochemistry 2017 Jun;141(5):676-693
Journal of neurochemistry 2017 Jun;141(5):676-693
CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke.
Arunachalam P, Ludewig P, Melich P, Arumugam TV, Gerloff C, Prinz I, Magnus T, Gelderblom M
Stroke 2017 Jul;48(7):1957-1965
Stroke 2017 Jul;48(7):1957-1965
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
Lu Y, Wang R, Dong Y, Tucker D, Zhao N, Ahmed ME, Zhu L, Liu TC, Cohen RM, Zhang Q
Neurobiology of aging 2017 Jan;49:165-182
Neurobiology of aging 2017 Jan;49:165-182
Ginsenoside Rg1 protects against sepsis-associated encephalopathy through beclin 1-independent autophagy in mice.
Li Y, Wang F, Luo Y
The Journal of surgical research 2017 Jan;207:181-189
The Journal of surgical research 2017 Jan;207:181-189
Early start of progressive motor deficits in Line 61 α-synuclein transgenic mice.
Rabl R, Breitschaedel C, Flunkert S, Duller S, Amschl D, Neddens J, Niederkofler V, Rockenstein E, Masliah E, Roemer H, Hutter-Paier B
BMC neuroscience 2017 Jan 31;18(1):22
BMC neuroscience 2017 Jan 31;18(1):22
Bexarotene protects against traumatic brain injury in mice partially through apolipoprotein E.
Zhong J, Cheng C, Liu H, Huang Z, Wu Y, Teng Z, He J, Zhang H, Wu J, Cao F, Jiang L, Sun X
Neuroscience 2017 Feb 20;343:434-448
Neuroscience 2017 Feb 20;343:434-448
Vanillin Protects Dopaminergic Neurons against Inflammation-Mediated Cell Death by Inhibiting ERK1/2, P38 and the NF-κB Signaling Pathway.
Yan X, Liu DF, Zhang XY, Liu D, Xu SY, Chen GX, Huang BX, Ren WZ, Wang W, Fu SP, Liu JX
International journal of molecular sciences 2017 Feb 12;18(2)
International journal of molecular sciences 2017 Feb 12;18(2)
Galangin Reduces the Loss of Dopaminergic Neurons in an LPS-Evoked Model of Parkinson's Disease in Rats.
Chen G, Liu J, Jiang L, Ran X, He D, Li Y, Huang B, Wang W, Fu S
International journal of molecular sciences 2017 Dec 21;19(1)
International journal of molecular sciences 2017 Dec 21;19(1)
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Shah SZA, Zhao D, Taglialatela G, Khan SH, Hussain T, Dong H, Lai M, Zhou X, Yang L
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Gypenoside Attenuates β Amyloid-Induced Inflammation in N9 Microglial Cells via SOCS1 Signaling.
Cai H, Liang Q, Ge G
Neural plasticity 2016;2016:6362707
Neural plasticity 2016;2016:6362707
Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model.
Jurga AM, Rojewska E, Piotrowska A, Makuch W, Pilat D, Przewlocka B, Mika J
Neural plasticity 2016;2016:5238730
Neural plasticity 2016;2016:5238730
Regulation and role of ERK phosphorylation in glial cells following a nigrostriatal pathway injury.
Li D, Tong L, Kawano H, Liu N, Yan HJ, Zhao L, Li HP
Brain research 2016 Oct 1;1648(Pt A):90-100
Brain research 2016 Oct 1;1648(Pt A):90-100
Trans-cinnamaldehyde improves memory impairment by blocking microglial activation through the destabilization of iNOS mRNA in mice challenged with lipopolysaccharide.
Zhang L, Zhang Z, Fu Y, Yang P, Qin Z, Chen Y, Xu Y
Neuropharmacology 2016 Nov;110(Pt A):503-518
Neuropharmacology 2016 Nov;110(Pt A):503-518
Participation of pro- and anti-nociceptive interleukins in botulinum toxin A-induced analgesia in a rat model of neuropathic pain.
Zychowska M, Rojewska E, Makuch W, Luvisetto S, Pavone F, Marinelli S, Przewlocka B, Mika J
European journal of pharmacology 2016 Nov 15;791:377-388
European journal of pharmacology 2016 Nov 15;791:377-388
Methylene Blue promotes cortical neurogenesis and ameliorates behavioral deficit after photothrombotic stroke in rats.
Ahmed ME, Tucker D, Dong Y, Lu Y, Zhao N, Wang R, Zhang Q
Neuroscience 2016 Nov 12;336:39-48
Neuroscience 2016 Nov 12;336:39-48
Impact of acquired and innate immunity on spinal cord ischemia and reperfusion injury.
Yamanaka K, Sasaki N, Fujita Y, Kawamoto A, Hirata K, Okita Y
General thoracic and cardiovascular surgery 2016 May;64(5):251-9
General thoracic and cardiovascular surgery 2016 May;64(5):251-9
Blockade of IL-18 signaling diminished neuropathic pain and enhanced the efficacy of morphine and buprenorphine.
Pilat D, Piotrowska A, Rojewska E, Jurga A, Ślusarczyk J, Makuch W, Basta-Kaim A, Przewlocka B, Mika J
Molecular and cellular neurosciences 2016 Mar;71:114-24
Molecular and cellular neurosciences 2016 Mar;71:114-24
Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model.
Rojewska E, Piotrowska A, Makuch W, Przewlocka B, Mika J
Neuropharmacology 2016 Mar;102:80-91
Neuropharmacology 2016 Mar;102:80-91
Expression of allograft inflammatory factor-1 in peripheral blood monocytes and synovial membranes in patients with rheumatoid arthritis.
Pawlik A, Kotrych D, Paczkowska E, Roginska D, Dziedziejko V, Safranow K, Machalinski B
Human immunology 2016 Jan;77(1):131-136
Human immunology 2016 Jan;77(1):131-136
Beneficial properties of maraviroc on neuropathic pain development and opioid effectiveness in rats.
Kwiatkowski K, Piotrowska A, Rojewska E, Makuch W, Jurga A, Slusarczyk J, Trojan E, Basta-Kaim A, Mika J
Progress in neuro-psychopharmacology & biological psychiatry 2016 Jan 4;64:68-78
Progress in neuro-psychopharmacology & biological psychiatry 2016 Jan 4;64:68-78
Treatment with a carbon monoxide-releasing molecule (CORM-2) inhibits neuropathic pain and enhances opioid effectiveness in rats.
Jurga AM, Piotrowska A, Starnowska J, Rojewska E, Makuch W, Mika J
Pharmacological reports : PR 2016 Feb;68(1):206-13
Pharmacological reports : PR 2016 Feb;68(1):206-13
Intrathecal Injection of Human Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorates Neuropathic Pain in Rats.
Chen C, Chen F, Yao C, Shu S, Feng J, Hu X, Hai Q, Yao S, Chen X
Neurochemical research 2016 Dec;41(12):3250-3260
Neurochemical research 2016 Dec;41(12):3250-3260
Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy.
Popiolek-Barczyk K, Kolosowska N, Piotrowska A, Makuch W, Rojewska E, Jurga AM, Pilat D, Mika J
Neural plasticity 2015;2015:676473
Neural plasticity 2015;2015:676473
NOD2 is involved in the inflammatory response after cerebral ischemia-reperfusion injury and triggers NADPH oxidase 2-derived reactive oxygen species.
Liu H, Wei X, Kong L, Liu X, Cheng L, Yan S, Zhang X, Chen L
International journal of biological sciences 2015;11(5):525-35
International journal of biological sciences 2015;11(5):525-35
Intervention with exercise restores motor deficits but not nigrostriatal loss in a progressive MPTP mouse model of Parkinson's disease.
Sconce MD, Churchill MJ, Greene RE, Meshul CK
Neuroscience 2015 Jul 23;299:156-74
Neuroscience 2015 Jul 23;299:156-74
Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson's disease models are mediated by GPR109A-dependent mechanisms.
Fu SP, Wang JF, Xue WJ, Liu HM, Liu BR, Zeng YL, Li SN, Huang BX, Lv QK, Wang W, Liu JX
Journal of neuroinflammation 2015 Jan 17;12:9
Journal of neuroinflammation 2015 Jan 17;12:9
The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain.
Zychowska M, Rojewska E, Makuch W, Przewlocka B, Mika J
European journal of pharmacology 2015 Feb 15;749:115-23
European journal of pharmacology 2015 Feb 15;749:115-23
Targeting the CD80/CD86 costimulatory pathway with CTLA4-Ig directs microglia toward a repair phenotype and promotes axonal outgrowth.
Louveau A, Nerrière-Daguin V, Vanhove B, Naveilhan P, Neunlist M, Nicot A, Boudin H
Glia 2015 Dec;63(12):2298-312
Glia 2015 Dec;63(12):2298-312
Chronic Noise Exposure Acts Cumulatively to Exacerbate Alzheimer's Disease-Like Amyloid-β Pathology and Neuroinflammation in the Rat Hippocampus.
Cui B, Li K, Gai Z, She X, Zhang N, Xu C, Chen X, An G, Ma Q, Wang R
Scientific reports 2015 Aug 7;5:12943
Scientific reports 2015 Aug 7;5:12943
Minocycline enhances the effectiveness of nociceptin/orphanin FQ during neuropathic pain.
Popiolek-Barczyk K, Rojewska E, Jurga AM, Makuch W, Zador F, Borsodi A, Piotrowska A, Przewlocka B, Mika J
BioMed research international 2014;2014:762930
BioMed research international 2014;2014:762930
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.
Ota K, Obayashi M, Ozaki K, Ichinose S, Kakita A, Tada M, Takahashi H, Ando N, Eishi Y, Mizusawa H, Ishikawa K
Acta neuropathologica communications 2014 Sep 11;2:136
Acta neuropathologica communications 2014 Sep 11;2:136
Photoreceptor degeneration, structural remodeling and glial activation: a morphological study on a genetic mouse model for pericyte deficiency.
Genové G, Mollick T, Johansson K
Neuroscience 2014 Oct 24;279:269-84
Neuroscience 2014 Oct 24;279:269-84
Genetics of gene expression characterizes response to selective breeding for alcohol preference.
Hoffman PL, Saba LM, Flink S, Grahame NJ, Kechris K, Tabakoff B
Genes, brain, and behavior 2014 Nov;13(8):743-57
Genes, brain, and behavior 2014 Nov;13(8):743-57
Cold-inducible RNA-binding protein mediates neuroinflammation in cerebral ischemia.
Zhou M, Yang WL, Ji Y, Qiang X, Wang P
Biochimica et biophysica acta 2014 Jul;1840(7):2253-61
Biochimica et biophysica acta 2014 Jul;1840(7):2253-61
Peripheral immunomodulation with ginsenoside Rg1 ameliorates neuroinflammation-induced behavioral deficits in rats.
Zheng X, Liang Y, Kang A, Ma SJ, Xing L, Zhou YY, Dai C, Xie H, Xie L, Wang GJ, Hao HP
Neuroscience 2014 Jan 3;256:210-22
Neuroscience 2014 Jan 3;256:210-22
Involvement of pro- and antinociceptive factors in minocycline analgesia in rat neuropathic pain model.
Rojewska E, Popiolek-Barczyk K, Jurga AM, Makuch W, Przewlocka B, Mika J
Journal of neuroimmunology 2014 Dec 15;277(1-2):57-66
Journal of neuroimmunology 2014 Dec 15;277(1-2):57-66
Maternal bisphenol a diet induces anxiety-like behavior in female juvenile with neuroimmune activation.
Luo G, Wang S, Li Z, Wei R, Zhang L, Liu H, Wang C, Niu R, Wang J
Toxicological sciences : an official journal of the Society of Toxicology 2014 Aug 1;140(2):364-73
Toxicological sciences : an official journal of the Society of Toxicology 2014 Aug 1;140(2):364-73
Minocycline influences the anti-inflammatory interleukins and enhances the effectiveness of morphine under mice diabetic neuropathy.
Zychowska M, Rojewska E, Kreiner G, Nalepa I, Przewlocka B, Mika J
Journal of neuroimmunology 2013 Sep 15;262(1-2):35-45
Journal of neuroimmunology 2013 Sep 15;262(1-2):35-45
ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy.
Elsherbiny NM, Ahmad S, Naime M, Elsherbini AM, Fulzele S, Al-Gayyar MM, Eissa LA, El-Shishtawy MM, Liou GI
Life sciences 2013 Jul 30;93(2-3):78-88
Life sciences 2013 Jul 30;93(2-3):78-88
Intraperitoneal administration of AAV9-shRNA inhibits target gene expression in the dorsal root ganglia of neonatal mice.
Machida A, Kuwahara H, Mayra A, Kubodera T, Hirai T, Sunaga F, Tajiri M, Hirai Y, Shimada T, Mizusawa H, Yokota T
Molecular pain 2013 Jul 18;9:36
Molecular pain 2013 Jul 18;9:36
Time course and progression of wild type α-synuclein accumulation in a transgenic mouse model.
Amschl D, Neddens J, Havas D, Flunkert S, Rabl R, Römer H, Rockenstein E, Masliah E, Windisch M, Hutter-Paier B
BMC neuroscience 2013 Jan 9;14:6
BMC neuroscience 2013 Jan 9;14:6
Effects of selective and non-selective inhibitors of nitric oxide synthase on morphine- and endomorphin-1-induced analgesia in acute and neuropathic pain in rats.
Makuch W, Mika J, Rojewska E, Zychowska M, Przewlocka B
Neuropharmacology 2013 Dec;75:445-57
Neuropharmacology 2013 Dec;75:445-57
Involvement of extraneural tissues and upregulation of inducible nitric oxide synthase after experimental infection with rabies virus in BALB/c mice and LEW/SsN rats.
Liao PH, Hsu YH, Yang HH, Wang MH, Chen LK
Pathology international 2012 Sep;62(9):619-27
Pathology international 2012 Sep;62(9):619-27
The dynamic expression of allograft inflammatory factor-1 in hepatic tissues and splenic cells of BALB/c mice with Schistosoma japonicum infection.
Chen QR, Guan F, Yan DJ, Lei DS, Fu L, Xia HS, Zhu YH, Chen ZW, Niu AO
Tissue antigens 2012 Jan;79(1):33-41
Tissue antigens 2012 Jan;79(1):33-41
Daintain/AIF-1 promotes breast cancer cell migration by up-regulated TNF-α via activate p38 MAPK signaling pathway.
Li T, Feng Z, Jia S, Wang W, Du Z, Chen N, Chen Z
Breast cancer research and treatment 2012 Feb;131(3):891-8
Breast cancer research and treatment 2012 Feb;131(3):891-8
17β-Estradiol increased the expression of daintain/AIF-1 in RAW264.7 macrophages.
Yan DJ, Chen ZW
Bioscience, biotechnology, and biochemistry 2010;74(10):2103-5
Bioscience, biotechnology, and biochemistry 2010;74(10):2103-5
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse spleen tissue were subjected to SDS PAGE followed by western blot with 10904-1-AP(IBA1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using AIF1 antibody 10904-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-IBA1 (IP:10904-1-AP, 3ug; Detection:10904-1-AP 1:500) with U-937 cells lysate 3000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 10904-1-AP(IBA1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
