14188-1-AP

antibody from Proteintech Group

Targeting: PRKCD

Provider product page for 14188-1-AP

Western blot

ELISA

Immunoprecipitation

Antibody data

Antibody Data
Antigen structure
References [16]
Comments [0]
Validations
Western blot [1]

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Product number: 14188-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#14188-1-AP, RRID:AB_10638614
Product name: PKC Delta antibody
Antibody type: Polyclonal
Description: PKC Delta antibody (Cat. #14188-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

PRKCD protein structure - 14188-1-AP shown in red.

Submitted references Electroacupuncture reduces calcium influx and inhibits endoplasmic reticulum stress by inhibiting the PKCδ-TRPA1 pathway to promote motor function recovery after spinal cord injury.

Zhang Y, Liang C, Huang Z, Hu Y, Mo Y, Ning S, Li Z, Wu Y, Zhang J, Li X, Wang Z
Burns & trauma 2026;14:tkaf066

Podocyte TLR4 deletion alleviates diabetic kidney disease through prohibiting PKCδ/SHP-1-dependent ER stress and relieving podocyte damage and inflammation.

Li Z, Tan D, Lin J, Zhang T, Liu B, Zhao B, Liang D, Li L, Wei X, Lv Z, Wang R, Hu M
Journal of advanced research 2026 Apr;82:845-862

A phosphoproteomic study uncovers the importance of PP2A-B56α in liver injury precipitated by NLRP3 activation during MC-LR exposure.

Yin H, Jiang H, Zhao R, Zhang Y, Fan X, Zhai X, Yang X, Zhang Y
Ecotoxicology and environmental safety 2025 Sep 1;302:118752

SIRT6 Lysine-Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE-Cadherin Pathway Regulating Vascular Endothelial Barrier.

Feng R, Fang Z, Zhao S, Zhang YE, Wu N, Guo Z, Zhong X, Jiang B, Xu H, Hong H, Zhang Z, Abdurahman M, Yu X, Geng J, Nie X, Abuduwahapi S, Huang D, Zhao G, Zhang W, Lu H, Shen L, Zhao X, Chen Z, Guo J, Zheng H, He Y, Wu S, Peng J, Song J, Wang X, Li H, Huang Y, Qin S, Lu H, Wang X, Zhao J, Huang L, Zhao Y, Li P, Ge J, Li H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e04948

Elevated Sphingosine Levels Suppress Profibrotic TGF-β Signaling via the PKC/miR-21/SMAD7 Axis in Sphingosine Kinase 2-Deficient Renal Fibroblasts and Unilateral Ureteral Obstruction-Induced Kidney Fibrosis.

Oftring A, Wagner V, Thomas D, Huber LS, Geisslinger G, Schaefer L, Vutukuri R, Pfeilschifter J, Schwalm S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70768

Podophyllotoxin mediates hepatic toxicity via the C5a/C5aR/ROS/NLRP3 and cGMP/PKG/mTOR axis in rats based on toxicological evidence chain (TEC) concept by phosphoproteomic analysis.

Liu C, Huang X, Kong J, Li X, Wang Y, Zhang F, Duan J
Ecotoxicology and environmental safety 2025 Jan 1;289:117441

LNCGM1082 in Gut Epithelial Cells Promotes Expulsion of Infected Epithelial Cells and Release of IL-18.

Wang Y, Gao Y, Su X, Hao Y, Zhang Y, Yang R
ImmunoHorizons 2024 Jan 1;8(1):35-46

PKCδ Regulates Chromatin Remodeling and DNA Repair through SIRT6.

Affandi T, Haas A, Ohm AM, Wright GM, Black JC, Reyland ME
Molecular cancer research : MCR 2024 Feb 1;22(2):181-196

Metabolic reprogramming contributes to radioprotection by protein kinase Cδ.

Ohm AM, Affandi T, Reisz JA, Caino MC, D'Alessandro A, Reyland ME
The Journal of biological chemistry 2023 Oct;299(10):105186

PKCδ regulates chromatin remodeling and DNA repair through SIRT6.

Affandi T, Haas A, Ohm AM, Wright GM, Black JC, Reyland ME
bioRxiv : the preprint server for biology 2023 May 24;

Tumor-Associated Fibroblast-Derived Exosomal circDennd1b Promotes Pituitary Adenoma Progression by Modulating the miR-145-5p/ONECUT2 Axis and Activating the MAPK Pathway.

Jiang Q, Lei Z, Wang Z, Wang Q, Zhang Z, Liu X, Xing B, Li S, Guo X, Liu Y, Li X, Qi Y, Shu K, Zhang H, Huang Y, Lei T
Cancers 2023 Jun 27;15(13)

ZCL-082, a boron-containing compound, induces apoptosis of non-Hodgkin's lymphoma via targeting p90 ribosomal S6 kinase 1/NF-κB signaling pathway.

Ma C, Liu M, Zhang J, Cai H, Wu Y, Zhang Y, Ji Y, Shan H, Zou Z, Yang L, Liu L, Xu H, Lei H, Liu C, Zhou L, Cao Y, Zhou H, Wu Y
Chemico-biological interactions 2022 Jan 5;351:109770

Theaflavin-3,3'-di-gallate represses prostate cancer by activating the PKCδ/aSMase signaling pathway through a 67 kDa laminin receptor.

Sun L, Wen S, Li Q, Lai X, Chen R, Zhang Z, Cao J, Sun S
Food & function 2022 Apr 20;13(8):4421-4431

Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms.

Saleiro D, Wen JQ, Kosciuczuk EM, Eckerdt F, Beauchamp EM, Oku CV, Blyth GT, Fischietti M, Ilut L, Colamonici M, Palivos W, Atsaves PA, Tan D, Kocherginsky M, Weinberg RS, Fish EN, Crispino JD, Hoffman R, Platanias LC
Nature communications 2022 Apr 1;13(1):1750

Tyrosine kinase inhibitors protect the salivary gland from radiation damage by increasing DNA double-strand break repair.

Affandi T, Ohm AM, Gaillard D, Haas A, Reyland ME
The Journal of biological chemistry 2021 Jan-Jun;296:100401

Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy.

Zhou H, Lei X, Yan Y, Lydic T, Li J, Weintraub NL, Su H, Chen W
JCI insight 2019 Jun 11;5(14)

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The PKC delta antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PKC delta. This antibody recognizes human,mouse,rat antigen. The PKC delta antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 14188-1-AP.pdf

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