Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 15054-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15054-1-AP, RRID:AB_2224138
- Product name
- AKR1A1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AKR1A1 antibody (Cat. #15054-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A new branch of mammalian vitamin B(6) metabolism: AKR1C-mediated conversion of pyridoxal to pyridoxine and 4-pyridoxolactone.
The denitrosylase SCoR2 controls cardioprotective metabolic reprogramming.
The denitrosylase SCoR2 controls cardioprotective metabolic reprogramming.
The protein denitrosylase SCoR2 regulates lipogenesis and fat storage.
Identification of a Selective SCoR2 Inhibitor That Protects Against Acute Kidney Injury.
AKR1A1 is a novel mammalian S-nitroso-glutathione reductase.
Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury.
Kito N, Kitaura Y, Iino K, Toriumi K, Noh H, Ogawa N, Arai M, Hemmi H, Ito T
The FEBS journal 2026 Feb 25;
The FEBS journal 2026 Feb 25;
The denitrosylase SCoR2 controls cardioprotective metabolic reprogramming.
Grimmett ZW, Zhang R, Zhou HL, Chen Q, Miller D, Qian Z, Lin J, Kalra R, Gross SS, Koch WJ, Premont RT, Stamler JS
eLife 2025 Nov 17;14
eLife 2025 Nov 17;14
The denitrosylase SCoR2 controls cardioprotective metabolic reprogramming.
Grimmett ZW, Zhang R, Zhou HL, Chen Q, Miller D, Qian Z, Lin J, Kalra R, Gross SS, Koch WJ, Premont RT, Stamler JS
bioRxiv : the preprint server for biology 2025 Jul 18;
bioRxiv : the preprint server for biology 2025 Jul 18;
The protein denitrosylase SCoR2 regulates lipogenesis and fat storage.
Venetos NM, Stomberski CT, Zhou HL, Qian Z, McLaughlin PJ, Bansal PK, Feczko J, Bederman I, Nguyen H, Hausladen A, Schindler JC, Grimmett ZW, Brunengraber H, Premont RT, Stamler JS
Science signaling 2025 Dec 23;18(918):eadv0660
Science signaling 2025 Dec 23;18(918):eadv0660
Identification of a Selective SCoR2 Inhibitor That Protects Against Acute Kidney Injury.
Zhou HL, Hausladen A, Anand P, Rajavel M, Stomberski CT, Zhang R, Premont RT, Greenlee WJ, van den Akker F, Stamler JS
Journal of medicinal chemistry 2023 Apr 27;66(8):5657-5668
Journal of medicinal chemistry 2023 Apr 27;66(8):5657-5668
AKR1A1 is a novel mammalian S-nitroso-glutathione reductase.
Stomberski CT, Anand P, Venetos NM, Hausladen A, Zhou HL, Premont RT, Stamler JS
The Journal of biological chemistry 2019 Nov 29;294(48):18285-18293
The Journal of biological chemistry 2019 Nov 29;294(48):18285-18293
Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury.
Zhou HL, Zhang R, Anand P, Stomberski CT, Qian Z, Hausladen A, Wang L, Rhee EP, Parikh SM, Karumanchi SA, Stamler JS
Nature 2019 Jan;565(7737):96-100
Nature 2019 Jan;565(7737):96-100
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The AKR1A1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AKR1A1. This antibody recognizes human,mouse,rat antigen. The AKR1A1 antibody has been validated for the following applications: ELISA, WB analysis.