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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 15633-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15633-1-AP, RRID:AB_2221535
- Product name
- ACOT2 antibody
- Antibody type
- Polyclonal
- Description
- ACOT2 antibody (Cat. #15633-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Txnrd2 loss in skeletal muscle causes muscle atrophy and drives leanness and obesity resistance.
Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation.
Quantitative label-free proteomic analysis of mouse ovarian antral follicles following oral exposure to a human-relevant mixture of three phthalates.
Transcriptome sequencing analysis reveals the molecular regulatory mechanism of myocardial hypertrophy induced by angiotensin II.
Application of microdialysis combined with lipidomics to analyze fatty acid metabolic changes in the disease process of rheumatoid arthritis.
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
Dysregulation of lipid metabolism in the pseudolobule promotes region-specific autophagy in hepatitis B liver cirrhosis.
Requirement of hepatic pyruvate carboxylase during fasting, high fat, and ketogenic diet.
High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo.
YY1 control of mitochondrial-related genes does not account for regulation of immunoglobulin class switch recombination in mice.
Up-Regulated MicroRNA-27b Promotes Adipocyte Differentiation via Induction of Acyl-CoA Thioesterase 2 Expression.
Kiermayer C, Erdelen R, Schriever SC, Böhm R, Prehn C, Artati A, Kleinert M, Miller M, Dyar KA, Schmid RM, Pfluger PT, Adamski J, Brielmeier M
Redox biology 2026 Jun;93:104165
Redox biology 2026 Jun;93:104165
Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation.
Guo W, Zhang C, Zhou Q, Chen T, Xu X, Zhang J, Yu X, Wu H, Zhang X, Ma L, Qian K, Klionsky DJ, Kang R, Kroemer G, Yu Y, Tang D, Wang J
Developmental cell 2025 Sep 8;60(17):2294-2312.e11
Developmental cell 2025 Sep 8;60(17):2294-2312.e11
Quantitative label-free proteomic analysis of mouse ovarian antral follicles following oral exposure to a human-relevant mixture of three phthalates.
Miller KL, Liu X, McSwain MG, Jauregui EJ, Langlais PR, Craig ZR
Toxicological sciences : an official journal of the Society of Toxicology 2024 Oct 1;201(2):226-239
Toxicological sciences : an official journal of the Society of Toxicology 2024 Oct 1;201(2):226-239
Transcriptome sequencing analysis reveals the molecular regulatory mechanism of myocardial hypertrophy induced by angiotensin II.
Zhang J, Sun J, Gu X, Shen Y, Sun H
Biochemical pharmacology 2024 Nov;229:116532
Biochemical pharmacology 2024 Nov;229:116532
Application of microdialysis combined with lipidomics to analyze fatty acid metabolic changes in the disease process of rheumatoid arthritis.
Jiang XM, Zhu YL, Gan PR, Li Y, Xia SL, Xu J, Wei Y, Deng R, Wu H
Journal of pharmaceutical and biomedical analysis 2024 Dec 15;251:116448
Journal of pharmaceutical and biomedical analysis 2024 Dec 15;251:116448
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
Southwell N, Primiano G, Nadkarni V, Attarwala N, Beattie E, Miller D, Alam S, Liparulo I, Shurubor YI, Valentino ML, Carelli V, Servidei S, Gross SS, Manfredi G, Chen Q, D'Aurelio M
EMBO molecular medicine 2023 Jul 10;15(7):e16951
EMBO molecular medicine 2023 Jul 10;15(7):e16951
Dysregulation of lipid metabolism in the pseudolobule promotes region-specific autophagy in hepatitis B liver cirrhosis.
Pu W, Wang X, Zhong X, Zhao D, Zeng Z, Cai W, Zhong Y, Huang J, Tang D, Dai Y
Hepatology communications 2023 Aug 1;7(8)
Hepatology communications 2023 Aug 1;7(8)
Requirement of hepatic pyruvate carboxylase during fasting, high fat, and ketogenic diet.
Selen ES, Rodriguez S, Cavagnini KS, Kim HB, Na CH, Wolfgang MJ
The Journal of biological chemistry 2022 Dec;298(12):102648
The Journal of biological chemistry 2022 Dec;298(12):102648
High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo.
Bonekamp NA, Jiang M, Motori E, Garcia Villegas R, Koolmeister C, Atanassov I, Mesaros A, Park CB, Larsson NG
Life science alliance 2021 Nov;4(11)
Life science alliance 2021 Nov;4(11)
YY1 control of mitochondrial-related genes does not account for regulation of immunoglobulin class switch recombination in mice.
Nandi S, Liang G, Sindhava V, Angireddy R, Basu A, Banerjee S, Hodawadekar S, Zhang Y, Avadhani NG, Sen R, Atchison ML
European journal of immunology 2020 Jun;50(6):822-838
European journal of immunology 2020 Jun;50(6):822-838
Up-Regulated MicroRNA-27b Promotes Adipocyte Differentiation via Induction of Acyl-CoA Thioesterase 2 Expression.
Murata Y, Yamashiro T, Kessoku T, Jahan I, Usuda H, Tanaka T, Okamoto T, Nakajima A, Wada K
BioMed research international 2019;2019:2916243
BioMed research international 2019;2019:2916243
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 15633-1-AP(ACOT2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-ACOT2 (IP:15633-1-AP, 3ug; Detection:15633-1-AP 1:500) with HepG2 cells lysate 1700ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 15633-1-AP(ACOT2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACOT2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ACOT2. This antibody recognizes human,mouse,rat antigen. The ACOT2 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
