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Learn15675-1-AP
antibody from Proteintech Group
Targeting: CD44
CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1
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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [447]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 15675-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15675-1-AP, RRID:AB_2076198
- Product name
- CD44 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CD44 antibody (Cat. #15675-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Targeting CAMK1D-engineered nanoactivator suppresses cancer stem cell maintenance and immune evasion in enzalutamide-resistant prostate cancer.
Medium-molecular weight hyaluronic acid orchestrates hair follicle regeneration via CD44/AKT-driven endogenous ROS activation of β-catenin.
Prognostic value and predictive biomarkers of synergistic interaction between tumor-associated macrophages and cancer stem cells in colorectal cancer.
Biomimetic Nanoplatform for Targeted Glioblastoma Therapy via Concurrently Triggering GPX4/DHODH Mediated Ferroptosis.
Lung Adenocarcinoma Promotes NETosis via the NPM1-TNFAIP6-CD44-SPP1 Axis.
A Rsv@HMnO(2)-HA nanozyme for AKI therapy via targeting inflammatory storm and activating SIRT1/PGC-1α to restore mitochondrial homeostasis.
Bovine Preadipocyte-Derived Exosomal miR-26a Promotes Intramuscular Adipogenesis by Directly Targeting GSK3B.
Downregulation of TDP43 by atovaquone inhibits oxidative phosphorylation and enhances sensitivity of triple-negative breast cancer to EGFR-TKIs.
Ginsenoside Ro alleviated cuproptosis induced by high oxalate via inhibiting zinc transporter ZnT1 in renal tubular epithelial cells.
Targeting astrocytic CLC2(CLCN2) restores myelin regeneration through inhibition of SPP1/CD44 signaling pathway in leukoencephalopathy.
SPP1 Drives Colorectal Cancer Liver Metastasis and Immunotherapy Resistance by Stimulating CXCL12 Production in Cancer-Associated Fibroblasts.
MEN1 Promotes Ferroptosis by Disrupting CD44 Alternative Splicing to Suppress Lung Cancer.
Goat bone marrow mesenchymal stem cell angiotensin-converting enzyme 2 attenuates Streptococcus uberis-induced ferroptosis in goat mammary epithelial cells by downregulating the reactive oxygen species-chaperone-mediated autophagy pathway.
Sulfated Pelvetia siliquosa Polysaccharides Attenuate Pyroptosis via NF-κB Pathway Inhibition Against Calcium Oxalate Stone Formation.
Citrate-coated Prussian blue nanozyme hitchhikes neutrophils to ameliorate calcium oxalate crystal-induced kidney injury via inhibiting pyroptosis and NETosis.
HSPA5 promotes YAP/TAZ stability independently of the Hippo pathway and induces proneural-to-mesenchymal transition in glioblastoma.
Integrated single-cell and spatial transcriptomic profiling decodes lineage plasticity and immune microenvironment remodeling in prostate cancer progression.
CD44 is associated with papillary thyroid carcinoma metastasis via potential modulation of the immunosuppressive tumor microenvironment.
Asporin regulates glycolysis and stemness of gastric cancer cells.
OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17-Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC.
Targeting keratin 6 A overcomes gemcitabine resistance by restoring equilibrative nucleoside transporter 1 and TAM-mediated metabolic compensation in pancreatic cancer.
KRT15 identified by scRNA-Seq and machine learning as stemness regulator and prognostic biomarker in ESCC.
Smad2 Cooperating with TGIF2 Contributes to EMT and Cancer Stem Cells Properties in Pancreatic Cancer via Co-Targeting SOX2.
Dot1l Regulates the Spontaneous Bone Regeneration of Periosteum-Derived Stem Cells by Regulating Chac1 Expression.
Single-Cell Transcriptomic Analysis Highlights the Impact of NFKB2-Mediated MIF-CD44 Signaling Axis in Endometrioid Endometrial Cancer.
Comprehensive analysis of IGFL1 in colorectal cancer and its promotion of tumour progression via inhibition of lipophagy.
Chrysin sensitizes glioblastoma cells and spheroids to temozolomide treatment by reducing EMT and stemness phenotypes, as well as targeting multidrug resistance proteins.
LINC01559 drives osimertinib resistance in NSCLC through a ceRNA network regulating miR-320a/IGF2BP3 axis.
Alpha-estradiol and (R)-(-)-ibuprofen inhibit gastric cancer progression via GLI1 G-quadruplex.
TNF‑α induces premature senescence in tendon stem cells via the NF‑κB and p53/p21/cyclin E/CDK2 signaling pathways.
Pien Tze Huang Attenuates Cell Proliferation and Stemness Promoted by miR-483-5p in Hepatocellular Carcinoma Cells.
The chromatin remodeling factor BAP18 promotes non-small cell lung cancer progression via the recruitment of β-catenin with the transcriptional coactivator complex ACTL6A-PAF1.
AMIGO2 accelerates tumor progression by inducing a cancer stem cell-like phenotype.
Neurodevelopmental hijacking of oligodendrocyte lineage programs drives glioblastoma infiltration.
Aurora kinase A drives non-canonical YAP1/TAZ crosstalk to sustain primary resistance to anti-EGFR therapies in colorectal cancer.
Stepwise targeting hyaluronic acid-based polymeric prodrug for acute kidney injury and prevents its progression to chronic kidney disease.
Magnesium hexacyanoferrate mitigates sepsis-associated encephalopathy through inhibiting microglial activation and neuronal cuproptosis.
Targeting MCM10 disrupts cancer stemness and counteracts sorafenib resistance in hepatocellular carcinoma.
Microcystin-LR facilitates pubertal bone retardation by interfering with glutamine metabolism to accelerate stem cell senescence through Hippo/GLS pathway.
Aucubin inhibits the activity of lung cancer stem-like cells by targeting degradation of β-catenin.
Enhanced lubricin secretion by human synovial mesenchymal stem cells compared to adipose mesenchymal stem cells.
Meningococci drive host membrane tubulation to recruit their signaling receptors.
Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by attenuating the malignancy of cancer stem cells via the gut microbiota-bile acid-FXR axis.
USP30-AS1 Dictates Breast Cancer Cell Fate and Chemoresistance via a miR-3646/FZD7/Wnt/β-Catenin Circuit.
Dual-Targeted Biomimetic Nanoparticles for Enhanced Delivery of Polyphyllin B Synergistically Induce Ferroptosis and Immunogenic Cell Death in Gastric Cancer.
Aberrantly High Expression of Steroid Receptor Coactivator-1 Drives Lung Cancer Growth and Metastasis by Enhancing Cancer Stemness.
E7 peptide modified poly(ε-caprolactone)/silk fibroin/octacalcium phosphate nanofiber membranes with "recruitment-osteoinduction" potentials for effective guided bone regeneration.
Drug Screening of Primary Human Endometriotic Cells Based on Micro-Encapsulating Microfluidic Chip.
A dual-targeting bio-liposomes nanodrug repair endothelial cell dysfunction and restore macrophage cholesterol flow homeostasis to treat early atherosclerosis.
Qingre Huayu Jianpi decoction suppresses colorectal tumorigenesis by inhibiting cancer stem cells and cancer-associated fibroblasts.
Streamlined metal-based hydrogel facilitates stem cell differentiation, extracellular matrix homeostasis and cartilage repair in male rats.
Molecular landscape of atherosclerotic plaque progression: insights from proteomics, single-cell transcriptomics and genomics.
KLF14 inhibits tumor progression via FOSL1 in glioma.
GNE-317 Reverses MSN-Mediated Proneural-to-Mesenchymal Transition and Suppresses Chemoradiotherapy Resistance in Glioblastoma via PI3K/mTOR.
Molecular signature of primate astrocytes reveals pathways and regulatory changes contributing to human brain evolution.
Fatty acid synthase inhibitor cerulenin attenuates glioblastoma progression by reducing EMT and stemness phenotypes, inducing oxidative and ER stress response, and targeting PI3K/AKT/NF-κB axis.
Increased HA/CD44/TGFβ signaling implicates in renal fibrosis of a Col4a5 mutant Alport mice.
CD44v6-mediated regulation of gastric cancer stem cells: a potential therapeutic target.
Macrophages-derived small extracellular vesicles regulate chondrocyte proliferation and affect osteoarthritis progression via upregulating Osteopontin expression.
Brown adipose tissue secretes OLFM4 to coordinate sensory and sympathetic innervation via Schwann cells.
Alpha-1 antitrypsin modulates neutrophil phenotype and function: implications for inflammatory regulation.
Precision medicine for acute kidney injury: Baicalein-nanodrug delivery system combat oxidative stress and repair mitochondrial dysfunction.
Alterations in gene expression associated with invasion of RAS-mutant thyroid tumors and their potential diagnostic and therapeutic utility.
TCF7 functions as a prognostic biomarker in bladder cancer by strengthening EMT and stemness associated with TGF-β/SMAD3 signaling.
Moesin silencing enhances the radiosensitivity of glioblastoma by inhibiting DNA damage repair via CD44/AKT1 signaling pathway.
The MIR181A2HG/miR-5680/VCAN-CD44 Axis Regulates Gastric Cancer Lymph Node Metastasis by Promoting M2 Macrophage Polarization.
Downregulation of ferroptosis-related ATF3 alleviates lupus nephritis progression.
MicroRNA-32-5p promotes the proliferation and metastasis of gastric cancer cells.
Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer.
Shen Qi Wan regulates OPN/CD44/PI3K pathway to improve airway inflammation in COPD: Network pharmacology, bioinformatics, and experimental validation.
CD44 is associated with muscle inflammation in polymyositis and skin damage in idiopathic inflammatory myopathy.
Neurotransmitter-Mimicking Nanovesicles Facilitate Postoperative Glioblastoma Stem Cell-Specific Treatment for Preventing Tumor Recurrence.
Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1.
Single-cell multi-omics analysis identifies SPP1(+) macrophages as key drivers of ferroptosis-mediated fibrosis in ligamentum flavum hypertrophy.
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Mechanistic studies of Ca(2+)-induced classical pyroptosis pathway promoting renal adhesion on calcium oxalate kidney stone formation.
Core-shell vector-mediated co-delivery of CRISPR/Cas9 system and hydrophobic drugs against triple-negative breast cancer stem cells.
N2 neutrophils induce cell stemness reprogramming to promote gastric cancer progression via exosomal miRNAs.
PRAS40 promotes colorectal cancer stemness by enhancing glycolysis through triggering PGK1 acetylation.
CAV2-expressing nerves induce metabolic switch toward mitochondrial oxidative phosphorylation to promote cancer stemness.
Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin.
Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity.
Lomibuvir sensitizes radioiodine-resistant thyroid cancer cell lines to radioiodine treatment by targeting hTERT RNA-dependent polymerase activity.
Combined downregulation of TGF-β1 and GRP78 is responsible for overcoming acquired sorafenib resistance, which is initiated by rewiring the cell surface CD44-GRP78-IGF-1R signaling circuit.
GATA2 promotes cervical cancer progression under the transcriptional activation of TRIP4.
Integrated network pharmacology and experimental validation reveal EGFR/p53/Bcl-2-mediated anti-hepatocellular carcinoma effects of Zedoary Turmeric Oil.
Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellular carcinoma.
Phospholipase D6 activates Wnt/β-catenin signaling through mitochondrial metabolic reprogramming to promote tumorigenesis in colorectal cancer.
M2 macrophages regulate nucleus pulposus cell extracellular matrix synthesis through the OPN-CD44 axis in intervertebral disc degeneration.
Hyaluronic acid-functionalized nanoparticles enable enhanced chemo/chemodynamic therapy for the targeted treatment of colon cancer.
Silencing of fibronectin type III domain-containing protein 3A (FNDC3A) attenuates epithelial-to-mesenchymal transition (EMT), cancer invasion, and stemness in triple-negative breast cancer (TNBC).
Shuxuetong injection inhibits pyroptosis in acute ischemic stroke via CD44/NLRP3/GSDMD signal.
CD44 on cancer stem cell is a potential immunological and prognostic pan-cancer biomarker.
P4HA1 is highly expressed in gastric cancer and promotes proliferation and metastasis of gastric cancer cells.
The development and potent antitumor efficacy of CD44/CD133 dual-targeting IL7Rα-armored CAR-T cells against glioblastoma.
Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes.
Hyaluronic acid-mediated epithelial-mesenchymal transition of human lens epithelial cells via CD44 and TGF-β2.
ΔNp63α promotes cigarette smoke-induced renal cancer stem cell activity via the Sonic Hedgehog pathway.
VEGFA/NRP-1/GAPVD1 axis promotes progression and cancer stemness of triple-negative breast cancer by enhancing tumor cell-macrophage crosstalk.
Exosomes Derived from Antler Mesenchymal Stem Cells Promote Wound Healing by miR-21-5p/STAT3 Axis.
Effect of Sonic hedgehog gene-modified bone marrow mesenchymal stem cells on graft-induced retinal gliosis and retinal ganglion cells survival in diabetic mice.
Investigating the mechanism and the effect of aquaporin 5 (AQP5) on the self-renewal capacity of gastric cancer stem cells.
Potential mechanism of Luoshi Neiyi prescription in endometriosis based on serum pharmacochemistry and network pharmacology.
USP7 regulates growth and maintains the stemness of p53-mutant colorectal cancer cells via stabilizing of mutant p53.
The prognostic value of co-expression of stemness markers CD44 and CD133 in endometrial cancer.
Molecular glue triggers degradation of PHGDH by enhancing the interaction between DDB1 and PHGDH.
Lyophilizable Stem Cell-Hybrid Liposome with Long-Term Stability and High Targeting Capacity.
Hyaluronic acid-coated polypeptide nanogel enhances specific distribution and therapy of tacrolimus in rheumatoid arthritis.
Phosphatase LHPP confers prostate cancer ferroptosis activation by modulating the AKT-SKP2-ACSL4 pathway.
LncRNA HOTAIRM1 promotes radioresistance in nasopharyngeal carcinoma by modulating FTO acetylation-dependent alternative splicing of CD44.
Biomimetic nanocomplex based corneal neovascularization theranostics.
Exploring the prognostic value of BRMS1 + microglia based on single-cell anoikis regulator patterns in the immunologic microenvironment of GBM.
Downregulation of short-stature homeobox protein 2 suppresses gastric cancer cell growth and stemness in vitro and in vivo via inactivating wnt/β-catenin signaling.
Short-term usage of proton pump inhibitors during admission was associated with increased risk of rehospitalization in critically ill patients with myocardial infarction: a cohort study.
Association of the podocyte phenotype with extracapillary hypercellularity in patients with diabetic kidney disease.
Dual-targeted halofuginone hydrobromide nanocomplexes for promotion of macrophage repolarization and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes in adjuvant-induced arthritis in rats.
CAFs-derived lactate enhances the cancer stemness through inhibiting the MST1 ubiquitination degradation in OSCC.
Single-cell sequencing reveals PTX3 involvement in ovarian cancer metastasis.
Tumor microenvironment remodeling after neoadjuvant chemoradiotherapy in local advanced rectal cancer revealed by single-cell RNA sequencing.
Platycodin D ameliorates polycystic ovary syndrome-induced ovarian damage by upregulating CD44 to attenuate ferroptosis.
The involvement of epidermal growth factor receptor/protein kinase B signaling in the tumor intrinsic PD-L1-induced malignant potential of oral squamous cell carcinoma.
YAP maintains cartilage stem/progenitor cell homeostasis in osteoarthritis.
Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus.
α5-nAChR/ADAM10 signaling mediates nicotine-related cutaneous melanoma progression via STAT3 activation.
Adipose stem cells-derived small extracellular vesicles transport Thrombospondin 1 cargo to promote insulin resistance in gestational diabetes mellitus.
Melatonin inhibits the stemness of head and neck squamous cell carcinoma by modulating HA synthesis via the FOSL1/HAS3 axis.
Squalene monooxygenase facilitates bladder cancer development in part by regulating PCNA.
ZNF217-activated Notch signaling mediates sulforaphane-suppressed stem cell properties in colorectal cancer.
Hinokitiol Inhibits Breast Cancer Cells In Vitro Stemness-Progression and Self-Renewal with Apoptosis and Autophagy Modulation via the CD44/Nanog/SOX2/Oct4 Pathway.
Mechanism of Porphyra Yezoensis Polysaccharides in Inhibiting Hyperoxalate-Induced Renal Injury and Crystal Deposition.
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
EphA2 promotes the transcription of KLF4 to facilitate stemness in oral squamous cell carcinoma.
Hypomethylation-enhanced CRTC2 expression drives malignant phenotypes and primary resistance to immunotherapy in hepatocellular carcinoma.
RANKL/RANK signaling recruits Tregs via the CCL20-CCR6 pathway and promotes stemness and metastasis in colorectal cancer.
Huaier enhances the tumor-killing effect and reverses gemcitabine-induced stemness by suppressing FoxM1.
Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues.
The demethylase ALKBH5 mediates ZKSCAN3 expression through the m(6)A modification to activate VEGFA transcription and thus participates in MNNG-induced gastric cancer progression.
Spatiotemporally sequential delivery of biomimetic liposomes potentiates glioma chemotherapy.
Engineering of targeting antioxidant polypeptide nanopolyplexes for the treatment of acute lung injury.
Combining microfluidic chip and low-attachment culture devices to isolate oral cancer stem cells.
BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma.
Oxidized ATM governs stemness of breast cancer stem cell through regulating ubiquitylation and acetylation switch.
Near-infrared-responsive GE11-CuS@Gal nanoparticles as an intelligent drug release system for targeting therapy against oral squamous cell carcinoma.
Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway.
Microscopic clusters feature the composition of biochemical tetraspanin-assemblies and constitute building-blocks of tetraspanin enriched domains.
Combining transcriptomics and network pharmacology to reveal the mechanism of Zuojin capsule improving spasmolytic polypeptide-expressing metaplasia.
PLEK2 mediates metastasis and invasion via α5-nAChR activation in nicotine-induced lung adenocarcinoma.
UDP-glucose dehydrogenase supports autophagy-deficient PDAC growth via increasing hyaluronic acid biosynthesis.
In-situ gelation of fibrin gel encapsulating platelet-rich plasma-derived exosomes promotes rotator cuff healing.
Molecular Mechanisms of Intracellular Delivery of Nanoparticles Monitored by an Enzyme-Induced Proximity Labeling.
Regulatory roles of NAMPT and NAD(+) metabolism in uterine leiomyoma progression: Implications for ECM accumulation, stemness, and microenvironment.
Effects of sulforaphane on prostate cancer stem cells-like properties: In vitro and molecular docking studies.
Rosmarinic acid attenuates glioblastoma cells and spheroids' growth and EMT/stem-like state by PTEN/PI3K/AKT downregulation and ERK-induced apoptosis.
Luoshi Neiyi Prescription inhibits estradiol synthesis and inflammation in endometriosis through the HIF1A/EZH2/SF-1 pathway.
Hyaluronic acid-modified extracellular vesicles for targeted doxorubicin delivery in hepatocellular carcinoma.
YAP/TAZ-TEAD activity promotes the malignant transformation of cervical intraepithelial neoplasia through enhancing the characteristics and Warburg effect of cancer stem cells.
Identifying polyamine related biomarkers in diagnosis and treatment of ulcerative colitis by integrating bulk and single-cell sequencing data.
Promotion of hepatocellular carcinoma stemness and progression by abnormal spindle-like microcephaly-associated protein via the Wnt/β-catenin pathway.
Homologous Tumor Cell-Derived Biomimetic Nano-Trojan Horse Integrating Chemotherapy with Genetherapy for Boosting Triple-Negative Breast Cancer Therapy.
A human fetal cerebellar map of the late second trimester reveals developmental molecular characteristics and abnormality in trisomy 21.
Early rhombic lip Protogenin(+ve) stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma.
tsRNA-GlyGCC promotes colorectal cancer progression and 5-FU resistance by regulating SPIB.
Inhibiting CD44-ICD Attenuates LPS-Induced Initiation of Hepatic Inflammation in Septic Mice.
LOXL2-induced PEAR1 Ser891 phosphorylation suppresses CD44 degradation and promotes triple-negative breast cancer metastasis.
Biomineralization-Tuned Nanounits Reprogram the Signal Transducer and Activator of Transcription 3 Signaling for Ferroptosis-Immunotherapy in Cancer Stem Cells.
H3K18 lactylation-mediated VCAM1 expression promotes gastric cancer progression and metastasis via AKT-mTOR-CXCL1 axis.
Mesothelin-based CAR-T cells exhibit potent antitumor activity against ovarian cancer.
Dysregulation of neuroprotective lipoxin pathway in astrocytes in response to cytokines and ocular hypertension.
A chemo/chemodynamic nanoparticle based on hyaluronic acid induces ferroptosis and apoptosis for triple-negative breast cancer therapy.
Sulforaphane Suppresses MCF-7 Breast Cancer Cells Growth via miR-19/PTEN Axis to Antagonize the Effect of Butyl Benzyl Phthalate.
Diallyl Trisulfide Suppresses the Renal Cancer Stem-like Cell Properties via Nanog.
Protective Effect of Alkaline Mineral Water on Calcium Oxalate-Induced Kidney Injury in Mice.
Extracellular vesicles carrying miR-6836 derived from resistant tumor cells transfer cisplatin resistance of epithelial ovarian cancer via DLG2-YAP1 signaling pathway.
FAK downregulation suppresses stem-like properties and migration of human colorectal cancer cells.
Decoding the Intercellular Cross-Talking Between Immune Cells and Renal Innate Cells in Diabetic Kidney Disease by Bioinformatics.
RUNX1/CD44 axis regulates the proliferation, migration, and immunotherapy of gliomas: A single-cell sequencing analysis.
Inhibition of Na+/H+ exchanger (NHE) 7 by 5-(N-ethyl-N-isopropyl)-Amiloride displays anti-cancer activity in non-small cell lung cancer by disrupting cancer stem cell activity and downregulating PD-L1 expression.
Vitamin D inhibits osteosarcoma by reprogramming nonsense-mediated RNA decay and SNAI2-mediated epithelial-to-mesenchymal transition.
YAP1 affects the prognosis through the regulation of stemness in endometrial cancer.
Radiated tumor cell-derived microparticles effectively kill stem-like tumor cells by increasing reactive oxygen species.
A novel TOX3-WDR5-ABCG2 signaling axis regulates the progression of colorectal cancer by accelerating stem-like traits and chemoresistance.
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance.
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
SEC61 translocon subunit gamma enhances low-dose cisplatin-induced cancer-stem cell properties of head and neck squamous cell carcinoma via enhancing Ca(2+)-mediated autophagy.
The PRX-1/TLR4 axis promotes hypoxia-induced radiotherapy resistance in non-small cell lung cancer by targeting the NF-κB/p65 pathway.
Fabrication of a Three-Dimensional Spheroid Culture System for Oral Squamous Cell Carcinomas Using a Microfabricated Device.
Dysregulation of Neuroprotective Lipoxin Pathway in Astrocytes in Response to Cytokines and Ocular Hypertension.
Histone acetyltransferase CSRP2BP promotes the epithelial-mesenchymal transition and metastasis of cervical cancer cells by activating N-cadherin.
Diallyl trisulfide inhibits gastric cancer stem cell properties through ΔNp63/sonic hedgehog pathway.
Single-Cell RNA Sequencing of Coronary Perivascular Adipose Tissue From End-Stage Heart Failure Patients Identifies SPP1(+) Macrophage Subpopulation as a Target for Alleviating Fibrosis.
Hyaluronan decorated layer-by-layer assembled lipid nanoparticles for miR-181a delivery in glioblastoma treatment.
Hyaluronan-CD44 Interaction Regulates Mouse Retinal Progenitor Cells Migration, Proliferation and Neuronal Differentiation.
Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy.
Black Phosphorus as a Targeting PPAR-γ Agonist to Reverse Chemoresistance in Patient-derived Organoids, Mice, and Pancreatic Tumor Cells.
The Critical Role of The Piezo1/β-catenin/ATF4 Axis on The Stemness of Gli1(+) BMSCs During Simulated Microgravity-Induced Bone Loss.
Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma.
Exosomes obtained from adipose mesenchymal stem cells prevent ischemia-reperfusion injury after torsion-detorsion in rat testes.
METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3.
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
EGFRvIII Promotes the Proneural-Mesenchymal Transition of Glioblastoma Multiforme and Reduces Its Sensitivity to Temozolomide by Regulating the NF-κB/ALDH1A3 Axis.
Low-dose phthalates promote breast cancer stem cell properties via the oncogene ΔNp63α and the Sonic hedgehog pathway.
Accelerate wound healing by microscale gel array patch encapsulating defined SDF-1α gradient.
Human amniotic mesenchymal stem cell-conditioned medium inhibited LPS-induced cell injury and inflammation by modulating CD14/TLR4-mediated signaling pathway in monocytes.
Integrated analysis based on vesicle trafficking-related genes identifying CNIH4 as a novel therapeutic target for glioma.
MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4.
LIMP-2 enhances cancer stem-like cell properties by promoting autophagy-induced GSK3β degradation in head and neck squamous cell carcinoma.
Identification of Piezo1 as a potential target for therapy of colon cancer stem-like cells.
Placental homing peptide guides HIF1α‑silenced exosomes conjugates for targeted enhancement of invasion of trophoblast cells.
Engineering a facile and versatile nanoplatform to facilitate the delivery of multiple agents for targeted breast cancer chemo-immunotherapy.
USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST1.
CD44 targeted indirubin nanocrystal-loaded hyaluronic acid hydrogel for the treatment of psoriasis.
Effects of non-steroidal anti-inflammatory drug (ibuprofen) in low and high dose on stemness and biological characteristics of human dental pulp-derived mesenchymal stem cells.
CD166-specific CAR-T cells potently target colorectal cancer cells.
Emodin reverses resistance to gemcitabine in pancreatic cancer by suppressing stemness through regulation of the epithelial‑mesenchymal transition.
3D Gelatin Microsphere Scaffolds Promote Functional Recovery after Spinal Cord Hemisection in Rats.
Sodium Butyrate Induces CRC Cell Ferroptosis via the CD44/SLC7A11 Pathway and Exhibits a Synergistic Therapeutic Effect with Erastin.
Sandwich Biomimetic Scaffold Based Tendon Stem/Progenitor Cell Alignment in a 3D Microenvironment for Functional Tendon Regeneration.
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection.
Leucine rich repeat containing 32 accelerates tenogenic differentiation of tendon-derived stem cells and promotes Achilles tendon repair in rats.
Macrophage-derived GPNMB trapped by fibrotic extracellular matrix promotes pulmonary fibrosis.
Apoptotic tumor cell-derived microparticles loading Napabucasin inhibit CSCs and synergistic immune therapy.
Integrating a phenotypic screening with a structural simplification strategy to identify 4-phenoxy-quinoline derivatives to potently disrupt the mitotic localization of Aurora kinase B.
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Biodegradable nano black phosphorus based SDF1-α delivery system ameliorates Erectile Dysfunction in a cavernous nerve injury rat model by recruiting endogenous stem/progenitor cells.
Dipeptidase‑2 is a prognostic marker in lung adenocarcinoma that is correlated with its sensitivity to cisplatin.
CD44 Drives M1 Macrophage Polarization in Diabetic Retinopathy.
CD44 expression is correlated with osteosarcoma cell progression and immune infiltration and affects the Wnt/β-catenin signaling pathway.
B7-H3 confers stemness characteristics to gastric cancer cells by promoting glutathione metabolism through AKT/pAKT/Nrf2 pathway.
Hyperthermia-triggered biomimetic bubble nanomachines.
Exosome miR-3184-5p inhibits gastric cancer growth by targeting XBP1 to regulate the AKT, STAT3, and IRE1 signalling pathways.
Preoperative administration of a biomimetic platelet nanodrug enhances postoperative drug delivery by bypassing thrombus.
EMT-activated secretory and endocytic vesicular trafficking programs underlie a vulnerability to PI4K2A antagonism in lung cancer.
Organoids From Mucinous Appendiceal Adenocarcinomas as High-Fidelity Models for Individual Therapy.
An Integrated Proteomics and Metabolomics Strategy for the Mechanism of Calcium Oxalate Crystal-Induced Kidney Injury.
DSC2 Suppresses the Metastasis of Gastric Cancer through Inhibiting the BRD4/Snail Signaling Pathway and the Transcriptional Activity of β-Catenin.
Antitumor Effect of Si-Jun-Zi Decoction on SGC7901 Gastric Cancer Cells by CMTM2 Activation.
Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis.
GALNT1 Enhances Malignant Phenotype of Gastric Cancer via Modulating CD44 Glycosylation to Activate the Wnt/β-catenin Signaling Pathway.
Self-Assembly Catalase Nanocomplex Conveyed by Bacterial Vesicles for Oxygenated Photodynamic Therapy and Tumor Immunotherapy.
Elevated Protein Kinase A Activity in Stomach Mesenchyme Disrupts Mesenchymal-epithelial Crosstalk and Induces Preneoplasia.
The Dibenzyl Isoquinoline Alkaloid Berbamine Ameliorates Osteoporosis by Inhibiting Bone Resorption.
IL25 Enhanced Colitis-Associated Tumorigenesis in Mice by Upregulating Transcription Factor GLI1.
The N(6)-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.
Polyphosphate-crosslinked collagen scaffolds for hemostasis and alveolar bone regeneration after tooth extraction.
ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2.
GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma.
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
CAFs-secreted exosomal cricN4BP2L2 promoted colorectal cancer stemness and chemoresistance by interacting with EIF4A3.
Dental pulp stem cells-based therapy for the oviduct injury via immunomodulation and angiogenesis in vivo.
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
Bortezomib prodrug catalytic nanoreactor for chemo/chemodynamic therapy and macrophage re-education.
Cellular Hypoxia Mitigation by Dandelion-like Nanoparticles for Synergistic Photodynamic Therapy of Oral Squamous Cell Carcinoma.
Babao Dan Alleviates 5-Fluorouracil-Induced Intestinal Damage via Wnt/β-Catenin Pathway.
CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway.
Regulation of ZO-1 on β-catenin mediates sulforaphane suppressed colorectal cancer stem cell properties in colorectal cancer.
CRISPR-mediated MECOM depletion retards tumor growth by reducing cancer stem cell properties in lung squamous cell carcinoma.
Treating intrauterine adhesion using conditionally reprogrammed physiological endometrial epithelial cells.
Upregulation of Runt related transcription factor 1 (RUNX1) contributes to tendon-bone healing after anterior cruciate ligament reconstruction using bone mesenchymal stem cells.
FAM64A promotes HNSCC tumorigenesis by mediating transcriptional autoregulation of FOXM1.
SPI1-induced downregulation of FTO promotes GBM progression by regulating pri-miR-10a processing in an m6A-dependent manner.
Claudin1 decrease induced by 1,25-dihydroxy-vitamin D3 potentiates gefitinib resistance therapy through inhibiting AKT activation-mediated cancer stem-like properties in NSCLC cells.
ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis.
TDO2 modulates liver cancer cell migration and invasion via the Wnt5a pathway.
Photosynthetic microorganisms coupled photodynamic therapy for enhanced antitumor immune effect.
SARS-CoV-2 productively infects human brain microvascular endothelial cells.
Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis.
Establishment of the SIS scaffold-based 3D model of human peritoneum for studying the dissemination of ovarian cancer.
Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.
Capsaicin inhibits the stemness of anaplastic thyroid carcinoma cells by triggering autophagy-lysosome mediated OCT4A degradation.
Epidermal growth factor/epidermal growth factor receptor signaling blockage inhibits tumor cell-derived exosome uptake by oral squamous cell carcinoma through macropinocytosis.
Proteome analysis of NRF2 inhibition in melanoma reveals CD44 up-regulation and increased apoptosis resistance upon vemurafenib treatment.
Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer.
A novel type of mesenchymal stem cells derived from bovine metanephric mesenchyme.
CCK regulates osteogenic differentiation through TNFα/NF-κB in peri-implantitis.
Endothelial cell-derived S1P promotes migration and stemness by binding with GPR63 in colorectal cancer.
Exosomes derived from bone marrow mesenchymal stem cells inhibit neuroinflammation after traumatic brain injury.
Chromium (VI)-induced ALDH1A1/EGF axis promotes lung cancer progression.
CD44 promotes angiogenesis in myocardial infarction through regulating plasma exosome uptake and further enhancing FGFR2 signaling transduction.
The Ginsenoside Compound K Suppresses Stem-Cell-like Properties and Colorectal Cancer Metastasis by Targeting Hypoxia-Driven Nur77-Akt Feed-Forward Signaling.
EBV promotes vascular mimicry of dormant cancer cells by potentiating stemness and EMT.
Multifunctional nanoparticles of sinomenine hydrochloride for treat-to-target therapy of rheumatoid arthritis via modulation of proinflammatory cytokines.
Sijunzi Decoction Inhibits Stemness by Suppressing β-Catenin Transcriptional Activity in Gastric Cancer Cells.
JUN activation modulates chromatin accessibility to drive TNFα-induced mesenchymal transition in glioblastoma.
CD44-fibrinogen binding promotes bleeding in acute promyelocytic leukemia by in situ fibrin(ogen) deposition.
Exosomal DEK removes chemoradiotherapy resistance by triggering quiescence exit of breast cancer stem cells.
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression.
Preclinical Application of Conditional Reprogramming Culture System for Laryngeal and Hypopharyngeal Carcinoma.
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness.
Sirt1 Promotes the Restoration of Hepatic Progenitor Cell (HPC)-Mediated Liver Fatty Injury in NAFLD Through Activating the Wnt/β-Catenin Signal Pathway.
MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Long noncoding RNA SH3PXD2A-AS1 promotes colorectal cancer progression by regulating p53-mediated gene transcription.
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Cronobacter sakazakii ATCC 29544 Translocated Human Brain Microvascular Endothelial Cells via Endocytosis, Apoptosis Induction, and Disruption of Tight Junction.
Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer.
The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resistant Prostate Cancer.
YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma.
The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway.
Discovering and Characterizing of Survivin Dominant Negative Mutants With Stronger Pro-apoptotic Activity on Cancer Cells and CSCs.
MiR-552-3p promotes malignant progression of gallbladder carcinoma by reactivating the Akt/β-catenin signaling pathway due to inhibition of the tumor suppressor gene RGMA.
Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma.
Circular RNA cia-MAF drives self-renewal and metastasis of liver tumor-initiating cells via transcription factor MAFF.
Single-Cell Analyses Reveal Mechanisms of Cancer Stem Cell Maintenance and Epithelial-Mesenchymal Transition in Recurrent Bladder Cancer.
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation.
A novel Lnc408 maintains breast cancer stem cell stemness by recruiting SP3 to suppress CBY1 transcription and increasing nuclear β-catenin levels.
Diallyl trisulfide inhibited tobacco smoke-mediated bladder EMT and cancer stem cell marker expression via the NF-κB pathway in vivo.
SHARPIN stabilizes β-catenin through a linear ubiquitination-independent manner to support gastric tumorigenesis.
SOCS6 promotes radiosensitivity and decreases cancer cell stemness in esophageal squamous cell carcinoma by regulating c-Kit ubiquitylation.
S100 calcium-binding protein A9 from tumor-associated macrophage enhances cancer stem cell-like properties of hepatocellular carcinoma.
Diallyl trisulphide, a H(2) S donor, compromises the stem cell phenotype and restores thyroid-specific gene expression in anaplastic thyroid carcinoma cells by targeting AKT-SOX2 axis.
Expression of CD44 and CD133 stem cell markers in squamous cell carcinoma of esophagus.
LncRNA LPAL2/miR-1287-5p/EGFR Axis Modulates TED-Derived Orbital Fibroblast Activation Through Cell Adhesion Factors.
A "dual-guide" bioinspired drug delivery strategy of a macrophage-based carrier against postoperative triple-negative breast cancer recurrence.
Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.
Grade-targeted nanoparticles for improved hypoxic tumor microenvironment and enhanced photodynamic cancer therapy.
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
RAB27A-dependent release of exosomes by liver cancer stem cells induces Nanog expression in their differentiated progenies and confers regorafenib resistance.
miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling.
EBV latent membrane proteins promote hybrid epithelial-mesenchymal and extreme mesenchymal states of nasopharyngeal carcinoma cells for tumorigenicity.
FOXD1 promotes EMT and cell stemness of oral squamous cell carcinoma by transcriptional activation of SNAI2.
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
CD44-Targeting Oxygen Self-Sufficient Nanoparticles for Enhanced Photodynamic Therapy Against Malignant Melanoma.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
ARPP-19 Mediates Herceptin Resistance via Regulation of CD44 in Gastric Cancer.
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells.
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
A sericin/ graphene oxide composite scaffold as a biomimetic extracellular matrix for structural and functional repair of calvarial bone.
Enrichment of CD44 in Exosomes From Breast Cancer Cells Treated With Doxorubicin Promotes Chemoresistance.
CCL21/CCR7 interaction promotes EMT and enhances the stemness of OSCC via a JAK2/STAT3 signaling pathway.
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
MicroRNA-148a-3p inhibits cancer progression and is a novel screening biomarker for gastric cancer.
5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation.
TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition.
Nanog mediates tobacco smoke-induced enhancement of renal cancer stem cell properties.
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
Destabilization of β-catenin and RAS by targeting the Wnt/β-catenin pathway as a potential treatment for triple-negative breast cancer.
The miRNA-149-5p/MyD88 axis is responsible for ursolic acid-mediated attenuation of the stemness and chemoresistance of non-small cell lung cancer cells.
KIAA1429 promotes osteosarcoma progression by promoting stem cell properties and is regulated by miR-143-3p.
A mutant KRAS-induced factor REG4 promotes cancer stem cell properties via Wnt/β-catenin signaling.
Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties.
Inhibition of miR-9 decreases osteosarcoma cell proliferation.
MiR-7 reduces the BCSC subset by inhibiting XIST to modulate the miR-92b/Slug/ESA axis and inhibit tumor growth.
Hypoxia-induced lncRNA PDIA3P1 promotes mesenchymal transition via sponging of miR-124-3p in glioma.
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
Stem-like tumor cells involved in heterogeneous vasculogenesis in breast cancer.
UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop.
P38 MAPK signaling pathway mediates COM crystal-induced crystal adhesion change in rat renal tubular epithelial cells.
Inhibition of breast cancer growth via miR-7 suppressing ALDH1A3 activity concomitant with decreasing breast cancer stem cell subpopulation.
RNA Binding Protein RNPC1 Suppresses the Stemness of Human Endometrial Cancer Cells via Stabilizing MST1/2 mRNA.
An all-silk-derived functional nanosphere matrix for sequential biomolecule delivery and in situ osteochondral regeneration.
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
Diospyros kaki leaves inhibit HGF/Met signaling-mediated EMT and stemness features in hepatocellular carcinoma.
WISP-2, an upregulated gene in hip cartilage from the DDH model rats, induces chondrocyte apoptosis through PPARγ in vitro.
The cancer cell glycocalyx proteoglycan Glypican-1 mediates interstitial flow mechanotransduction to enhance cell migration and metastasis.
Human colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF.
CD44 3'-Untranslated Region Functions as a Competing Endogenous RNA to Enhance NK Sensitivity of Liver Cancer Stem Cell by Regulating ULBP2 Expression.
Nuclear CD44 Mediated by Importin β Participated in Naïve Genes Transcriptional Regulation in C3A-iCSCs.
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling.
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer.
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
FNDC3B circular RNA promotes the migration and invasion of gastric cancer cells via the regulation of E-cadherin and CD44 expression.
Targeting Frizzled-7 Decreases Stemness and Chemotherapeutic Resistance in Gastric Cancer Cells by Suppressing Myc Expression.
In-vivo anti-tumor activity of a novel poloxamer-based thermosensitive in situ gel for sustained delivery of norcantharidin.
PES1 is regulated by CD44 in liver cancer stem cells via miR-105-5p.
WDR76 degrades RAS and suppresses cancer stem cell activation in colorectal cancer.
Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.
BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.
Osterix promotes the migration and angiogenesis of breast cancer by upregulation of S100A4 expression.
MicroRNA-135a-5p promotes neuronal differentiation of pluripotent embryonal carcinoma cells by repressing Sox6/CD44 pathway.
Metabolomic analysis reveals a protective effect of Fu-Fang-Jin-Qian-Chao herbal granules on oxalate-induced kidney injury.
Pseudomonas aeruginosa ExsA Regulates a Metalloprotease, ImpA, That Inhibits Phagocytosis of Macrophages.
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
A Therapeutic Strategy for Chemotherapy-Resistant Gastric Cancer via Destabilization of Both β-Catenin and RAS.
Long non-coding RNA DILC promotes the progression of gallbladder carcinoma.
The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling.
Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19.
CD44 is overexpressed and correlated with tumor progression in gallbladder cancer.
Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells.
Tumor suppressor LKB1 inhibits the progression of gallbladder carcinoma and predicts the prognosis of patients with this malignancy.
LGR5, a novel functional glioma stem cell marker, promotes EMT by activating the Wnt/β-catenin pathway and predicts poor survival of glioma patients.
Isobavachalcone sensitizes cells to E2-induced paclitaxel resistance by down-regulating CD44 expression in ER+ breast cancer cells.
Proteomic Analysis of Plasma Membrane Proteins of Antler Stem Cells Using Label-Free LC⁻MS/MS.
Studying the mechanism of PLAGL2 overexpression and its carcinogenic characteristics based on 3'-untranslated region in colorectal cancer.
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system.
Endogenous and exogenous galectin-3 promote the adhesion of tumor cells with low expression of MUC1 to HUVECs through upregulation of N-cadherin and CD44.
miR-1307-3p suppresses the chondrogenic differentiation of human adipose-derived stem cells by targeting BMPR2.
Inhibiting transforming growth factor-β signaling regulates in vitro maintenance and differentiation of bovine bone marrow mesenchymal stem cells.
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability.
High-resolution acoustophoretic 3D cell patterning to construct functional collateral cylindroids for ischemia therapy.
CD44-targeted hyaluronic acid-curcumin prodrug protects renal tubular epithelial cell survival from oxidative stress damage.
A Ultrasensitive Near-Infrared Fluorescent Probe Reveals Pyroglutamate Aminopeptidase 1 Can Be a New Inflammatory Cytokine.
Histochemical evidence of IGF2 mRNA-binding protein 2-mediated regulation of osteoclast function and adhesive ability.
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
miR34a/GOLPH3 Axis abrogates Urothelial Bladder Cancer Chemoresistance via Reduced Cancer Stemness.
β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Prohibitin, relocated to the front ends, can control the migration directionality of colorectal cancer cells.
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Overexpression of PER3 Inhibits Self-Renewal Capability and Chemoresistance of Colorectal Cancer Stem-Like Cells via Inhibition of Notch and β-Catenin Signaling.
Adipocytes enhance expression of osteoclast adhesion-related molecules through the CXCL12/CXCR4 signalling pathway.
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
DACH1 suppresses breast cancer as a negative regulator of CD44.
S100P is associated with proliferation and migration in nasopharyngeal carcinoma.
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Autophagy plays an important role in stemness mediation and the novel dual function of EIG121 in both autophagy and stemness regulation of endometrial carcinoma JEC cells.
SLC39A4 expression is associated with enhanced cell migration, cisplatin resistance, and poor survival in non-small cell lung cancer.
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Sulfiredoxin May Promote Cervical Cancer Metastasis via Wnt/β-Catenin Signaling Pathway.
CD44+ cancer cell-induced metastasis: A feasible neck metastasis model.
Hypoxia Promotes Gastric Cancer Malignancy Partly through the HIF-1α Dependent Transcriptional Activation of the Long Non-coding RNA GAPLINC.
MiR-21-5p Links Epithelial-Mesenchymal Transition Phenotype with Stem-Like Cell Signatures via AKT Signaling in Keloid Keratinocytes.
MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer.
CD44 correlates with clinicopathological characteristics and is upregulated by EGFR in breast cancer.
Extracellular serglycin upregulates the CD44 receptor in an autocrine manner to maintain self-renewal in nasopharyngeal carcinoma cells by reciprocally activating the MAPK/β-catenin axis.
NIBP impacts on the expression of E-cadherin, CD44 and vimentin in colon cancer via the NF-κB pathway.
EB-virus latent membrane protein 1 potentiates the stemness of nasopharyngeal carcinoma via preferential activation of PI3K/AKT pathway by a positive feedback loop.
KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway.
NOTCH1 inhibition enhances the efficacy of conventional chemotherapeutic agents by targeting head neck cancer stem cell.
Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice.
Vorinostat protects against calcium oxalate-induced kidney injury in mice.
Histochemical evidence of zoledronate inhibiting c-src expression and interfering with CD44/OPN-mediated osteoclast adhesion in the tibiae of mice.
Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells.
Knock out CD44 in reprogrammed liver cancer cell C3A increases CSCs stemness and promotes differentiation.
CD163+ tumor-associated macrophages correlated with poor prognosis and cancer stem cells in oral squamous cell carcinoma.
Expression and clinical significance of colorectal cancer stem cell marker EpCAM(high)/CD44(+) in colorectal cancer.
Cancer stem-like cell characteristics induced by EB virus-encoded LMP1 contribute to radioresistance in nasopharyngeal carcinoma by suppressing the p53-mediated apoptosis pathway.
Amyloid-β precursor protein promotes cell proliferation and motility of advanced breast cancer.
Correlation of ALDH1, CD44, OCT4 and SOX2 in tongue squamous cell carcinoma and their association with disease progression and prognosis.
Nanotopographical cues augment mesenchymal differentiation of human embryonic stem cells.
Wentilactone B from Aspergillus wentii induces apoptosis and inhibits proliferation and migration of human hepatoma SMMC-7721 cells.
Sun F, Yan Y, Sun D, Liu S, Dong Z, Pan G, Zhang L, Shao X, Xu Y, Qu Y, Li T
Theranostics 2026;16(6):2918-2935
Theranostics 2026;16(6):2918-2935
Medium-molecular weight hyaluronic acid orchestrates hair follicle regeneration via CD44/AKT-driven endogenous ROS activation of β-catenin.
Liu J, Piao M, Zhou Y, Yang C, Zhao B
International journal of biological macromolecules 2026 May;360:151752
International journal of biological macromolecules 2026 May;360:151752
Prognostic value and predictive biomarkers of synergistic interaction between tumor-associated macrophages and cancer stem cells in colorectal cancer.
Kou Y, Wang Y, Yang R, Tang H, Gu F, Han B, Wang Y
Molecular and clinical oncology 2026 Mar;24(3):16
Molecular and clinical oncology 2026 Mar;24(3):16
Biomimetic Nanoplatform for Targeted Glioblastoma Therapy via Concurrently Triggering GPX4/DHODH Mediated Ferroptosis.
Ren G, Wang X, Li P, Wu H, Bi Z, Gao Q, Ma B, Tian Z, Liu J, Feng F, Liu W, Li L, Zhang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 23;:e21236
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 23;:e21236
Lung Adenocarcinoma Promotes NETosis via the NPM1-TNFAIP6-CD44-SPP1 Axis.
Liu R, Hu Z, Li M, Yang S, Wang J, Zhang Z, Yang L, Chen J
Cancers 2026 Mar 22;18(6)
Cancers 2026 Mar 22;18(6)
A Rsv@HMnO(2)-HA nanozyme for AKI therapy via targeting inflammatory storm and activating SIRT1/PGC-1α to restore mitochondrial homeostasis.
Su J, Wu L, Zhu H, Wang H, He X, Liang B, Cai J
Journal of advanced research 2026 Mar 17;
Journal of advanced research 2026 Mar 17;
Bovine Preadipocyte-Derived Exosomal miR-26a Promotes Intramuscular Adipogenesis by Directly Targeting GSK3B.
Du Y, Guo J, Zhao Z, Qin L, Zhang J, Zhao Y, Peng Y
Journal of agricultural and food chemistry 2026 Mar 11;74(9):7442-7453
Journal of agricultural and food chemistry 2026 Mar 11;74(9):7442-7453
Downregulation of TDP43 by atovaquone inhibits oxidative phosphorylation and enhances sensitivity of triple-negative breast cancer to EGFR-TKIs.
Lin L, Ke H, Chen M, Zhang Y, Fu S, Yu F, Su J, Yang X, Guo Y, Ding Q, Zhang Y, Zhao L
Free radical biology & medicine 2026 Jul;250:64-79
Free radical biology & medicine 2026 Jul;250:64-79
Ginsenoside Ro alleviated cuproptosis induced by high oxalate via inhibiting zinc transporter ZnT1 in renal tubular epithelial cells.
Li C, Zhou Y, Nie Y, Fu J, Zeng J, Zhang S, Han L, Li Z, Yang H, Li S, Yu B, Ying X, Wu W
Journal of ginseng research 2026 Jan;50(1):100908
Journal of ginseng research 2026 Jan;50(1):100908
Targeting astrocytic CLC2(CLCN2) restores myelin regeneration through inhibition of SPP1/CD44 signaling pathway in leukoencephalopathy.
Yang L, Lu Y, Liu J, Zhu F, Jiang Y, Lu T, Zhong X, Qiu W, Tang C, Peng F
Molecular psychiatry 2026 Jan;31(1):116-136
Molecular psychiatry 2026 Jan;31(1):116-136
SPP1 Drives Colorectal Cancer Liver Metastasis and Immunotherapy Resistance by Stimulating CXCL12 Production in Cancer-Associated Fibroblasts.
Liu S, Zhang Z, Wang Z, Liu C, Liang G, Xu T, Li Z, Duan X, Xu G, Feng X, Feng Q, Wang Q, Han D, Zhang C, Li J, Shen L
Cancer research 2026 Jan 2;86(1):58-79
Cancer research 2026 Jan 2;86(1):58-79
MEN1 Promotes Ferroptosis by Disrupting CD44 Alternative Splicing to Suppress Lung Cancer.
Pan T, Zhu J, Wang X, Tang D, Wang Z, Yang Y, Teng Y, Tian Q, Dan G, Chen C, Yu D, Liu M, Wang H, Zhang T, Guo B, Chen T, Jin B
Cancer research 2026 Jan 2;86(1):146-166
Cancer research 2026 Jan 2;86(1):146-166
Goat bone marrow mesenchymal stem cell angiotensin-converting enzyme 2 attenuates Streptococcus uberis-induced ferroptosis in goat mammary epithelial cells by downregulating the reactive oxygen species-chaperone-mediated autophagy pathway.
Wu G, Xu J, Chen X, Wang G, Zhang Y
Journal of dairy science 2026 Feb;109(2):1854-1873
Journal of dairy science 2026 Feb;109(2):1854-1873
Sulfated Pelvetia siliquosa Polysaccharides Attenuate Pyroptosis via NF-κB Pathway Inhibition Against Calcium Oxalate Stone Formation.
Tong XY, Chen XW, Zhang JY, Ouyang JM
Marine drugs 2026 Feb 8;24(2)
Marine drugs 2026 Feb 8;24(2)
Citrate-coated Prussian blue nanozyme hitchhikes neutrophils to ameliorate calcium oxalate crystal-induced kidney injury via inhibiting pyroptosis and NETosis.
Ba X, Yang X, He Y, Ye T, Zeng X, Zhong Z, Guo X, Tang K
Journal of nanobiotechnology 2026 Feb 7;24(1)
Journal of nanobiotechnology 2026 Feb 7;24(1)
HSPA5 promotes YAP/TAZ stability independently of the Hippo pathway and induces proneural-to-mesenchymal transition in glioblastoma.
Gui S, Yu W, Song Z, Peng L, Luo H, Huang K, Xiao J, Xie J, Cai S, Yuan S, Tao Z, Cheng Z
Cell death & disease 2026 Feb 7;17(1):208
Cell death & disease 2026 Feb 7;17(1):208
Integrated single-cell and spatial transcriptomic profiling decodes lineage plasticity and immune microenvironment remodeling in prostate cancer progression.
Yu H, Wang Y, He M, Chen Y, Bi J, Lin X, Cui X
Molecular cancer 2026 Feb 28;25(1)
Molecular cancer 2026 Feb 28;25(1)
CD44 is associated with papillary thyroid carcinoma metastasis via potential modulation of the immunosuppressive tumor microenvironment.
Adeerjiang Y, Huo MH, Ma L, Li XX, Tian Y, Bai C, Wang BW, Qu X, Yao XY, Ma LL, Gan XX, Kuang JY, Liang HZ, Qiang BR, Wang R, Bao JL, Jiang S, Du GL
Clinical and experimental medicine 2026 Feb 25;26(1)
Clinical and experimental medicine 2026 Feb 25;26(1)
Asporin regulates glycolysis and stemness of gastric cancer cells.
Xu G, Cai Z, Zhuang Y, Wang H, Lin Q, Guo T, Tao H
Journal of molecular histology 2026 Feb 13;57(2):74
Journal of molecular histology 2026 Feb 13;57(2):74
OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17-Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC.
Cui L, Si S, Ye M, Lin P, Zou M, Lin Y, Chen X, Guo B, Sun W, Zhao X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e15452
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e15452
Targeting keratin 6 A overcomes gemcitabine resistance by restoring equilibrative nucleoside transporter 1 and TAM-mediated metabolic compensation in pancreatic cancer.
Zhang J, Wang X, Zeng S, Tang B, Yang X, Xie S, Sun H, Wang R, Xia R, Li J, Wang H, Shi Z, Gu J, Wei D
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Apr 17;87:101404
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Apr 17;87:101404
KRT15 identified by scRNA-Seq and machine learning as stemness regulator and prognostic biomarker in ESCC.
Xiong K, Zhu Y, Fang H, Sun X, Li Z, Tuerxun D, Zhang P
iScience 2026 Apr 17;29(4):115020
iScience 2026 Apr 17;29(4):115020
Smad2 Cooperating with TGIF2 Contributes to EMT and Cancer Stem Cells Properties in Pancreatic Cancer via Co-Targeting SOX2.
Zu F, Chen C, Geng Q, Li H, Chan B, Luo G, Wu M, Ilmer M, Renz BW, Bentum-Ennin L, Gu H, Sheng W
International journal of biological sciences 2025;21(2):524-543
International journal of biological sciences 2025;21(2):524-543
Dot1l Regulates the Spontaneous Bone Regeneration of Periosteum-Derived Stem Cells by Regulating Chac1 Expression.
Jiang T, Fang B, Yu Z, Cao D
Stem cells international 2025;2025:1508850
Stem cells international 2025;2025:1508850
Single-Cell Transcriptomic Analysis Highlights the Impact of NFKB2-Mediated MIF-CD44 Signaling Axis in Endometrioid Endometrial Cancer.
Zhang L, Yang M, Zhang Q, Zhang Y, Li Q, Chen Q
International journal of women's health 2025;17:3293-3313
International journal of women's health 2025;17:3293-3313
Comprehensive analysis of IGFL1 in colorectal cancer and its promotion of tumour progression via inhibition of lipophagy.
Wang A, Zhou Y, Deng Z, Duan Y, Dai Z, Jiang D
Frontiers in immunology 2025;16:1719525
Frontiers in immunology 2025;16:1719525
Chrysin sensitizes glioblastoma cells and spheroids to temozolomide treatment by reducing EMT and stemness phenotypes, as well as targeting multidrug resistance proteins.
Aksüt Y, Şengelen A, Gürsoy DM, Öğütcü İ, Kuvet Ö, Pekmez M
Frontiers in pharmacology 2025;16:1643186
Frontiers in pharmacology 2025;16:1643186
LINC01559 drives osimertinib resistance in NSCLC through a ceRNA network regulating miR-320a/IGF2BP3 axis.
Xu L, Zhang Y, Xing L, Zhou Y, Chang N, Xi H, Xu X, Zhang J
Frontiers in pharmacology 2025;16:1592846
Frontiers in pharmacology 2025;16:1592846
Alpha-estradiol and (R)-(-)-ibuprofen inhibit gastric cancer progression via GLI1 G-quadruplex.
Li Q, Pan P, Xian Q, Li J, Wang J, Cai J, Wang J, Jia Y, Sun H, Zhang L, Ma X
Frontiers in pharmacology 2025;16:1492694
Frontiers in pharmacology 2025;16:1492694
TNF‑α induces premature senescence in tendon stem cells via the NF‑κB and p53/p21/cyclin E/CDK2 signaling pathways.
Guo H, Cao H, Lu Q, Gu Z, Feng G
International journal of molecular medicine 2025 Sep;56(3)
International journal of molecular medicine 2025 Sep;56(3)
Pien Tze Huang Attenuates Cell Proliferation and Stemness Promoted by miR-483-5p in Hepatocellular Carcinoma Cells.
Wei LH, Chen X, Shen AL, Fang Y, Xie QR, Guo Z, Sferra TJ, Chen YQ, Peng J
Chinese journal of integrative medicine 2025 Sep;31(9):782-791
Chinese journal of integrative medicine 2025 Sep;31(9):782-791
The chromatin remodeling factor BAP18 promotes non-small cell lung cancer progression via the recruitment of β-catenin with the transcriptional coactivator complex ACTL6A-PAF1.
Hao J, Hu Q, Li X, Shi S, Na F, Zeng K, Li H, Zhao Y, Zhao M
The Journal of biological chemistry 2025 Sep;301(9):110596
The Journal of biological chemistry 2025 Sep;301(9):110596
AMIGO2 accelerates tumor progression by inducing a cancer stem cell-like phenotype.
Seong HK, Osaki M, Izutsu R, Jehung JP, Sato R, Sasaki R, Hamada J, Yamamoto A, Takenaka A, Okada F
Scientific reports 2025 Sep 25;15(1):32861
Scientific reports 2025 Sep 25;15(1):32861
Neurodevelopmental hijacking of oligodendrocyte lineage programs drives glioblastoma infiltration.
Wu Y, Wu BZ, Ellenbogen Y, Kant JBY, Yu P, Li X, Caloren L, Sotov V, Tran C, Restrepo M, Kushida M, Ayyadhury S, Kossinna P, Lau R, Habibi P, Mansouri S, Regala J, Durbic T, Aboualizadeh F, Tsao J, Ketela T, Pugh T, Butler MO, Wang BX, Dirks PB, Gao A, Zadeh G, Gaiti F
Developmental cell 2025 Sep 22;60(18):2420-2433.e12
Developmental cell 2025 Sep 22;60(18):2420-2433.e12
Aurora kinase A drives non-canonical YAP1/TAZ crosstalk to sustain primary resistance to anti-EGFR therapies in colorectal cancer.
Rio-Vilariño A, Garcia-Bautista A, Cenigaonandia-Campillo A, Mateos-Gomez PA, Garcia-Garcia L, Schlaepfer MI, Garcia-Hernandez L, Puerto-Nevado LD, Aguilera O, Baños N, Minguez P, Castellano VM, Garcia-Foncillas J, Cebrian A
Molecular therapy. Oncology 2025 Sep 18;33(3):201032
Molecular therapy. Oncology 2025 Sep 18;33(3):201032
Stepwise targeting hyaluronic acid-based polymeric prodrug for acute kidney injury and prevents its progression to chronic kidney disease.
Zhou LB, Peng XZ, Long HM, Hu JB, Xu JT
Materials today. Bio 2025 Oct;34:102207
Materials today. Bio 2025 Oct;34:102207
Magnesium hexacyanoferrate mitigates sepsis-associated encephalopathy through inhibiting microglial activation and neuronal cuproptosis.
Zhang Y, Xin J, Zhao D, Chen G, Ji P, Liu P, Wei H, Wang H, Xia Y, Wang Y, Wang Z, Ren X, Huo M, Yu H, Yang J
Biomaterials 2025 Oct;321:123279
Biomaterials 2025 Oct;321:123279
Targeting MCM10 disrupts cancer stemness and counteracts sorafenib resistance in hepatocellular carcinoma.
Zhang Z, Liang L, Li Y, Fan Y, Liu Y, He Z, Wu X, Cong L, Jiang Y, Wan T
Cancer gene therapy 2025 Oct;32(10):1076-1089
Cancer gene therapy 2025 Oct;32(10):1076-1089
Microcystin-LR facilitates pubertal bone retardation by interfering with glutamine metabolism to accelerate stem cell senescence through Hippo/GLS pathway.
Pan C, Liu T, Fan Z, Ma B, Wang K, Wang X, Zhang Y, Hong R, Chen H
Environmental pollution (Barking, Essex : 1987) 2025 Oct 15;383:126931
Environmental pollution (Barking, Essex : 1987) 2025 Oct 15;383:126931
Aucubin inhibits the activity of lung cancer stem-like cells by targeting degradation of β-catenin.
Li Q, Xie H, Li L, Yan W, Liu G
The Journal of pharmacy and pharmacology 2025 Nov 28;77(12):1777-1786
The Journal of pharmacy and pharmacology 2025 Nov 28;77(12):1777-1786
Enhanced lubricin secretion by human synovial mesenchymal stem cells compared to adipose mesenchymal stem cells.
Takakuwa T, Endo K, Ozeki N, Nakagawa Y, Koga H, Tomita M, Sekiya I
Stem cell research & therapy 2025 Nov 26;16(1):697
Stem cell research & therapy 2025 Nov 26;16(1):697
Meningococci drive host membrane tubulation to recruit their signaling receptors.
Laurent-Granger A, Sollier K, Saubamea B, Mignon V, Goudin N, Wormser Y, Wuckelt M, Rifai M, Heng T, L'hermitte L, Conflitti M, Meyer J, Lecuyer H, Jamet A, Borghi N, Girard P, Bille E, Lavieu G, Rubinstein E, Marullo S, Coureuil M
Nature communications 2025 Nov 25;16(1):10433
Nature communications 2025 Nov 25;16(1):10433
Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by attenuating the malignancy of cancer stem cells via the gut microbiota-bile acid-FXR axis.
Zhang Y, Shen M, Baokan J, Xu L, Ni M, Jin J, Shen W, Sun D, Li L, Lai Y, Yan Q, Yu C, Tan J, Xu C, Tao L, Fan M, Cheng H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157366
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157366
USP30-AS1 Dictates Breast Cancer Cell Fate and Chemoresistance via a miR-3646/FZD7/Wnt/β-Catenin Circuit.
He Q, Yang S, Xin Q, Jiang Y, Jiang L, Xu N
Current issues in molecular biology 2025 Nov 24;47(12)
Current issues in molecular biology 2025 Nov 24;47(12)
Dual-Targeted Biomimetic Nanoparticles for Enhanced Delivery of Polyphyllin B Synergistically Induce Ferroptosis and Immunogenic Cell Death in Gastric Cancer.
Zu D, Yao J, Li X, Huang Y, Hu C, Deng M, Bao Q, Shi Y, Ye Z, Cheng X
ACS applied materials & interfaces 2025 Nov 12;17(45):61676-61694
ACS applied materials & interfaces 2025 Nov 12;17(45):61676-61694
Aberrantly High Expression of Steroid Receptor Coactivator-1 Drives Lung Cancer Growth and Metastasis by Enhancing Cancer Stemness.
Pan J, Zhou H, Liu L, Xu S, Hou Y, Cheng K, Li Y, Zhu C, Wu N, Bai C, Wang R, Liu C, Wang R, Yuan Y
Biomolecules & therapeutics 2025 Nov 1;33(6):1004-1014
Biomolecules & therapeutics 2025 Nov 1;33(6):1004-1014
E7 peptide modified poly(ε-caprolactone)/silk fibroin/octacalcium phosphate nanofiber membranes with "recruitment-osteoinduction" potentials for effective guided bone regeneration.
Xiao Y, Qu Y, Hu X, Zhao J, Xu S, Zheng L, Liang X
International journal of biological macromolecules 2025 May;305(Pt 1):140862
International journal of biological macromolecules 2025 May;305(Pt 1):140862
Drug Screening of Primary Human Endometriotic Cells Based on Micro-Encapsulating Microfluidic Chip.
Chen Q, Wang J, Li W, Shang L, Wang D, Duan P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2504647
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2504647
A dual-targeting bio-liposomes nanodrug repair endothelial cell dysfunction and restore macrophage cholesterol flow homeostasis to treat early atherosclerosis.
Zhang Q, Ma S, Kang X, Liu Y, Ma F, Yu F, Luo X, Li G, Hao Y, Zhang H, Liu B, Jiang Y
Journal of nanobiotechnology 2025 May 20;23(1):365
Journal of nanobiotechnology 2025 May 20;23(1):365
Qingre Huayu Jianpi decoction suppresses colorectal tumorigenesis by inhibiting cancer stem cells and cancer-associated fibroblasts.
Guirong C, Lili H, Guifang D, Weiqi L, Xiongbo G, Fan X, Zhenyu N, Jinbin S, Gang C, Lina Z, Wenfeng G, Qun D, Yanwu L
Journal of ethnopharmacology 2025 May 12;347:119722
Journal of ethnopharmacology 2025 May 12;347:119722
Streamlined metal-based hydrogel facilitates stem cell differentiation, extracellular matrix homeostasis and cartilage repair in male rats.
Li W, Shi Z, Jing H, Dou Y, Liu X, Zhang M, Qiu Z, Heger Z, Li N
Nature communications 2025 May 10;16(1):4344
Nature communications 2025 May 10;16(1):4344
Molecular landscape of atherosclerotic plaque progression: insights from proteomics, single-cell transcriptomics and genomics.
Wang C, Feng Y, Liu X, Sun H, Guo Z, Shao J, Li K, Chen J, Shu K, Kong D, Wang J, Li Y, Lei X, Li C, Liu B, Sun W, Lai Z
BMC medicine 2025 May 1;23(1):254
BMC medicine 2025 May 1;23(1):254
KLF14 inhibits tumor progression via FOSL1 in glioma.
Wang X, Qu X, Liu X, Wang K, Yang Y, Zhang Y, Wang Z, Fan G, Li Y, Zeng Y, Chen H, Zhu T
Biochemistry and biophysics reports 2025 Mar;41:101885
Biochemistry and biophysics reports 2025 Mar;41:101885
GNE-317 Reverses MSN-Mediated Proneural-to-Mesenchymal Transition and Suppresses Chemoradiotherapy Resistance in Glioblastoma via PI3K/mTOR.
Yang YC, Jin XY, Yang LL, Xu X, Xie Y, Ai YD, Li XC, Ma YC, Xu CL, Li Q, Ge XL, Yi TL, Jiang T, Wang XG, Piao YZ, Jin X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2412517
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2412517
Molecular signature of primate astrocytes reveals pathways and regulatory changes contributing to human brain evolution.
Ciuba K, Piotrowska A, Chaudhury D, Dehingia B, Duński E, Behr R, Soroczyńska K, Czystowska-Kuźmicz M, Abbas M, Bulanda E, Gawlik-Zawiślak S, Pietrzak S, Figiel I, Włodarczyk J, Verkhratsky A, Niedbała M, Kaspera W, Wypych T, Wilczyński B, Pękowska A
Cell stem cell 2025 Mar 6;32(3):426-444.e14
Cell stem cell 2025 Mar 6;32(3):426-444.e14
Fatty acid synthase inhibitor cerulenin attenuates glioblastoma progression by reducing EMT and stemness phenotypes, inducing oxidative and ER stress response, and targeting PI3K/AKT/NF-κB axis.
Pekmez M, Mete ŞB, Aksüt Y, Öğütcü İ, Baştürk FN, Gerçek YC, Şengelen A
Medical oncology (Northwood, London, England) 2025 Mar 25;42(5):136
Medical oncology (Northwood, London, England) 2025 Mar 25;42(5):136
Increased HA/CD44/TGFβ signaling implicates in renal fibrosis of a Col4a5 mutant Alport mice.
Bao Y, Wu W, Lin J, Yang Y, Lin S, Su J, Qin Y, Wang B, Duan S
Molecular medicine (Cambridge, Mass.) 2025 Mar 12;31(1):96
Molecular medicine (Cambridge, Mass.) 2025 Mar 12;31(1):96
CD44v6-mediated regulation of gastric cancer stem cells: a potential therapeutic target.
Chen H, Ling R, Lai J, Liu Z, Wang Z, Yang H, Kong Y
Clinical and experimental medicine 2025 Mar 12;25(1):80
Clinical and experimental medicine 2025 Mar 12;25(1):80
Macrophages-derived small extracellular vesicles regulate chondrocyte proliferation and affect osteoarthritis progression via upregulating Osteopontin expression.
Tu M, Liu AM, Huang W, Wang D, Chen HQ, Hu XY
Journal of cell communication and signaling 2025 Jun;19(2):e70008
Journal of cell communication and signaling 2025 Jun;19(2):e70008
Brown adipose tissue secretes OLFM4 to coordinate sensory and sympathetic innervation via Schwann cells.
Lai M, Zhou W, Zou W, Qiu L, Liang Z, Chen W, Wang Y, Guo B, Zhao C, Zhang S, Lai P, Hu L, Liu X, Jiang Y, Chen Y, Huang MJ, Bai X, Zou Z
Nature communications 2025 Jun 4;16(1):5206
Nature communications 2025 Jun 4;16(1):5206
Alpha-1 antitrypsin modulates neutrophil phenotype and function: implications for inflammatory regulation.
Oshins R, Patel I, Khartabil L, Katikaneni DS, Scindia Y, Khodayari N
Journal of leukocyte biology 2025 Jun 4;117(6)
Journal of leukocyte biology 2025 Jun 4;117(6)
Precision medicine for acute kidney injury: Baicalein-nanodrug delivery system combat oxidative stress and repair mitochondrial dysfunction.
Zhou X, Wang N, Zhao B, Liu Z, Yu P
International journal of pharmaceutics 2025 Jun 10;678:125694
International journal of pharmaceutics 2025 Jun 10;678:125694
Alterations in gene expression associated with invasion of RAS-mutant thyroid tumors and their potential diagnostic and therapeutic utility.
Condello V, Doerfler WR, Nikitski AV, Spagnolo DM, Fornal IJ, Schmidt GM, Wald AI, Nikiforova MN, Nikiforov YE
European thyroid journal 2025 Jun 1;14(3)
European thyroid journal 2025 Jun 1;14(3)
TCF7 functions as a prognostic biomarker in bladder cancer by strengthening EMT and stemness associated with TGF-β/SMAD3 signaling.
Zhang C, Cai H, Ye M, Wang L, Liu W, Huang Q, Peng X, Mao G, Zhang Q, Mei Y
Molecular and cellular biochemistry 2025 Jul;480(7):4135-4148
Molecular and cellular biochemistry 2025 Jul;480(7):4135-4148
Moesin silencing enhances the radiosensitivity of glioblastoma by inhibiting DNA damage repair via CD44/AKT1 signaling pathway.
Ding X, Wang Y, Shao Z, Wen X, Wang B, Liu G, Xu C, Chai L, Qiu H, Zhang L
Discover oncology 2025 Jul 31;16(1):1451
Discover oncology 2025 Jul 31;16(1):1451
The MIR181A2HG/miR-5680/VCAN-CD44 Axis Regulates Gastric Cancer Lymph Node Metastasis by Promoting M2 Macrophage Polarization.
Zang W, Yang Y, Chen J, Mao Q, Xue W, Hu Y
Cancer medicine 2025 Jan;14(2):e70600
Cancer medicine 2025 Jan;14(2):e70600
Downregulation of ferroptosis-related ATF3 alleviates lupus nephritis progression.
Xiao G, Tang S, Zhang Y, Yuan Q, Sun D, Wang W
Gene 2025 Jan 20;934:149009
Gene 2025 Jan 20;934:149009
MicroRNA-32-5p promotes the proliferation and metastasis of gastric cancer cells.
Sun C, Huang LG, Leng B, Guo Y, Chen C, Lv R, Dong Y, Gao TT, Sun DQ
Scientific reports 2025 Jan 17;15(1):2282
Scientific reports 2025 Jan 17;15(1):2282
Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer.
Teng Y, Zhao H, Xue G, Zhang G, Huang Y, Guo W, Zou K, Zou L
Journal of translational medicine 2025 Jan 11;23(1):44
Journal of translational medicine 2025 Jan 11;23(1):44
Shen Qi Wan regulates OPN/CD44/PI3K pathway to improve airway inflammation in COPD: Network pharmacology, bioinformatics, and experimental validation.
Huang J, Zhou X, Xu Y, Yu C, Zhang H, Qiu J, Wei J, Luo Q, Xu Z, Lin Y, Qiu P, Li C
International immunopharmacology 2025 Jan 10;144:113624
International immunopharmacology 2025 Jan 10;144:113624
CD44 is associated with muscle inflammation in polymyositis and skin damage in idiopathic inflammatory myopathy.
Zhou Y, Zhao Y, Yin G, Kang L, Zhu X, Xie Q
Clinical and experimental rheumatology 2025 Feb;43(2):241-250
Clinical and experimental rheumatology 2025 Feb;43(2):241-250
Neurotransmitter-Mimicking Nanovesicles Facilitate Postoperative Glioblastoma Stem Cell-Specific Treatment for Preventing Tumor Recurrence.
Liang F, You Q, Yu B, Wang C, Yang Y, Zhu L, He Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2409713
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2409713
Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1.
Xie B, Wu P, Liu H, Yang X, Huang L
Journal of translational medicine 2025 Feb 7;23(1):165
Journal of translational medicine 2025 Feb 7;23(1):165
Single-cell multi-omics analysis identifies SPP1(+) macrophages as key drivers of ferroptosis-mediated fibrosis in ligamentum flavum hypertrophy.
Fei C, Chen Y, Tan R, Yang X, Wu G, Li C, Shi J, Le S, Yang W, Xu J, Wang L, Zhang Z
Biomarker research 2025 Feb 25;13(1):33
Biomarker research 2025 Feb 25;13(1):33
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Wu Y, Meng L, Zhan S, Li M, Huang J, Chen X, Chen L, Gao X, Chen H, Chen H, Zhong Y, Xu L, Xu Y
Journal of translational medicine 2025 Feb 24;23(1):224
Journal of translational medicine 2025 Feb 24;23(1):224
Mechanistic studies of Ca(2+)-induced classical pyroptosis pathway promoting renal adhesion on calcium oxalate kidney stone formation.
Xiang J, Lv M, Luo Y, Ke K, Zhang B, Wang M, Zhang K, Li H
Scientific reports 2025 Feb 24;15(1):6669
Scientific reports 2025 Feb 24;15(1):6669
Core-shell vector-mediated co-delivery of CRISPR/Cas9 system and hydrophobic drugs against triple-negative breast cancer stem cells.
Wang T, Chen T, Li D, Hang X, Zhang S, Yi H, Jiang T, Ding D, Zhang X
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:1080-1091
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:1080-1091
N2 neutrophils induce cell stemness reprogramming to promote gastric cancer progression via exosomal miRNAs.
Tang H, Zhong Y, Wang J, Meng S, Yu D, Fan B, Dong X, Wang M, Fu M, Qian Y, Zhang X, Ji R, Zhang X, Fang X, Zhang J
Cellular signalling 2025 Dec;136:112085
Cellular signalling 2025 Dec;136:112085
PRAS40 promotes colorectal cancer stemness by enhancing glycolysis through triggering PGK1 acetylation.
Zhang C, Bo Y, Zhang T, Chen X, Zhang T, Teng H, Wang Y, Luo Y, Sun J, Wang L, Wang X, Huang L
Oncogenesis 2025 Dec 27;15(1):2
Oncogenesis 2025 Dec 27;15(1):2
CAV2-expressing nerves induce metabolic switch toward mitochondrial oxidative phosphorylation to promote cancer stemness.
Zhang Z, Wang C, Sun Z, Shi X, Shuai Y, Wang Y, Wang Y, Guo H, Liu R, Luo J
Nature communications 2025 Dec 2;17(1):203
Nature communications 2025 Dec 2;17(1):203
Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin.
Xi SY, Zhang H, Wang QJ, Liu YJ, Chang SC, Shi CF, Fang D, Tao LH, Cheng HB, Zou X
Journal of cancer research and clinical oncology 2025 Dec 17;152(1):12
Journal of cancer research and clinical oncology 2025 Dec 17;152(1):12
Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity.
Li Y, Sheng M, Li W, Liu S, Wang B, Liu B, Luo M, Zhou X, Xia Q, Hong S, Zheng Z, Cheng SY, Jiang X, Li J, Huang T
Nature communications 2025 Dec 13;17(1):440
Nature communications 2025 Dec 13;17(1):440
Lomibuvir sensitizes radioiodine-resistant thyroid cancer cell lines to radioiodine treatment by targeting hTERT RNA-dependent polymerase activity.
Cheng X, Xu S, Wu J, Gao W, Bao J, Yu H, Zhang L
Journal of endocrinological investigation 2025 Aug;48(8):1797-1810
Journal of endocrinological investigation 2025 Aug;48(8):1797-1810
Combined downregulation of TGF-β1 and GRP78 is responsible for overcoming acquired sorafenib resistance, which is initiated by rewiring the cell surface CD44-GRP78-IGF-1R signaling circuit.
Li S, Oh GH, Hong JA, Choi S, Kim M, Kwon H, Ko SK, Park SJ, Kim HK, Choi HJ, Song JJ
Cancer gene therapy 2025 Aug;32(8):884-898
Cancer gene therapy 2025 Aug;32(8):884-898
GATA2 promotes cervical cancer progression under the transcriptional activation of TRIP4.
Wang R, Zhang F, Li J, Yang D, Zhao H, Yuan J, Jia Y, Yu W, Guo W, Zou L, Zou K
Cellular signalling 2025 Aug;132:111778
Cellular signalling 2025 Aug;132:111778
Integrated network pharmacology and experimental validation reveal EGFR/p53/Bcl-2-mediated anti-hepatocellular carcinoma effects of Zedoary Turmeric Oil.
Zhong M, Li Y, Wang H, Fan N, Chu X, Liu L, Zhao C, Sun Y, Zhang S, Fu H
Journal of ethnopharmacology 2025 Aug 29;352:120241
Journal of ethnopharmacology 2025 Aug 29;352:120241
Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellular carcinoma.
Huang H, Peng W, Zhou Q, Zhao Y, Liu L, Cui H, Liang J, Cao M, Chen W, Wang R, Chen S, Xiong S, Cheng B, Bai S
Cell communication and signaling : CCS 2025 Aug 25;23(1):379
Cell communication and signaling : CCS 2025 Aug 25;23(1):379
Phospholipase D6 activates Wnt/β-catenin signaling through mitochondrial metabolic reprogramming to promote tumorigenesis in colorectal cancer.
Lee HJ, Lim SH, Lee H, Han JM, Min DS
Experimental & molecular medicine 2025 Apr;57(4):910-924
Experimental & molecular medicine 2025 Apr;57(4):910-924
M2 macrophages regulate nucleus pulposus cell extracellular matrix synthesis through the OPN-CD44 axis in intervertebral disc degeneration.
Tao Z, Zhang T, Ge Y, Li L, Ma C, Wang Z, Chen T, Zhang H, Li R, Jiang T, Ren Y
Osteoarthritis and cartilage 2025 Apr;33(4):447-460
Osteoarthritis and cartilage 2025 Apr;33(4):447-460
Hyaluronic acid-functionalized nanoparticles enable enhanced chemo/chemodynamic therapy for the targeted treatment of colon cancer.
Liu S, Tong S, Liu G, Wang S, Zhang K, Qiu Z
International journal of biological macromolecules 2025 Apr;303:140553
International journal of biological macromolecules 2025 Apr;303:140553
Silencing of fibronectin type III domain-containing protein 3A (FNDC3A) attenuates epithelial-to-mesenchymal transition (EMT), cancer invasion, and stemness in triple-negative breast cancer (TNBC).
Wada N, Sakai S, Inoue Y, Nishizuka M
Biochimica et biophysica acta. Molecular cell research 2025 Apr;1872(4):119935
Biochimica et biophysica acta. Molecular cell research 2025 Apr;1872(4):119935
Shuxuetong injection inhibits pyroptosis in acute ischemic stroke via CD44/NLRP3/GSDMD signal.
Shang J, Huang G, Wang B, Wang J, Wei W, Cui Y, Liu X
Journal of ethnopharmacology 2025 Apr 9;345:119618
Journal of ethnopharmacology 2025 Apr 9;345:119618
CD44 on cancer stem cell is a potential immunological and prognostic pan-cancer biomarker.
Zhu YJ, Li SY, Yang SS, Du Y, Zhang ZY, Liu JY
Cancer cell international 2025 Apr 8;25(1):134
Cancer cell international 2025 Apr 8;25(1):134
P4HA1 is highly expressed in gastric cancer and promotes proliferation and metastasis of gastric cancer cells.
Gao P, Tian H, Ge K, Wang F, Zhao Y, Sun J, Zhang Q
Discover oncology 2025 Apr 19;16(1):575
Discover oncology 2025 Apr 19;16(1):575
The development and potent antitumor efficacy of CD44/CD133 dual-targeting IL7Rα-armored CAR-T cells against glioblastoma.
Zhai Y, Li G, Pan C, Yu M, Hu H, Wang D, Shi Z, Jiang T, Zhang W
Cancer letters 2025 Apr 1;614:217541
Cancer letters 2025 Apr 1;614:217541
Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes.
Wang W, Cheng Z, Yu M, Liu K, Duan H, Zhang Y, Huang X, Li M, Li C, Hu Y, Luo Z, Liu M
Nature communications 2025 Apr 1;16(1):3131
Nature communications 2025 Apr 1;16(1):3131
Hyaluronic acid-mediated epithelial-mesenchymal transition of human lens epithelial cells via CD44 and TGF-β2.
Gui Y, Peng J, Jiang S
Arquivos brasileiros de oftalmologia 2024;88(1):e20230163
Arquivos brasileiros de oftalmologia 2024;88(1):e20230163
ΔNp63α promotes cigarette smoke-induced renal cancer stem cell activity via the Sonic Hedgehog pathway.
Zhao Y, Ma N, Wu W, Wu Y, Zhang W, Qian W, Sun X, Zhang T
Genetics and molecular biology 2024;47(2):e20230347
Genetics and molecular biology 2024;47(2):e20230347
VEGFA/NRP-1/GAPVD1 axis promotes progression and cancer stemness of triple-negative breast cancer by enhancing tumor cell-macrophage crosstalk.
Wang L, Zhang L, Zhao L, Shao S, Ning Q, Jing X, Zhang Y, Zhao F, Liu X, Gu S, Zhao X, Luo M
International journal of biological sciences 2024;20(2):446-463
International journal of biological sciences 2024;20(2):446-463
Exosomes Derived from Antler Mesenchymal Stem Cells Promote Wound Healing by miR-21-5p/STAT3 Axis.
Meng D, Li Y, Chen Z, Guo J, Yang M, Peng Y
International journal of nanomedicine 2024;19:11257-11273
International journal of nanomedicine 2024;19:11257-11273
Effect of Sonic hedgehog gene-modified bone marrow mesenchymal stem cells on graft-induced retinal gliosis and retinal ganglion cells survival in diabetic mice.
Wang T, Li HC, Ma J, Yu XL
International journal of ophthalmology 2024;17(1):34-41
International journal of ophthalmology 2024;17(1):34-41
Investigating the mechanism and the effect of aquaporin 5 (AQP5) on the self-renewal capacity of gastric cancer stem cells.
Gao P, Chen A, Tian H, Wang F, Wang N, Ge K, Lian C, Wang F, Zhang Q
Journal of Cancer 2024;15(13):4313-4327
Journal of Cancer 2024;15(13):4313-4327
Potential mechanism of Luoshi Neiyi prescription in endometriosis based on serum pharmacochemistry and network pharmacology.
Wu L, Lin S, Hu Y, Jing S, Sun B, Chen X, Jia J, Zeng C, Pei F
Frontiers in pharmacology 2024;15:1395160
Frontiers in pharmacology 2024;15:1395160
USP7 regulates growth and maintains the stemness of p53-mutant colorectal cancer cells via stabilizing of mutant p53.
Li X, Pan J, Zheng P
Frontiers in oncology 2024;14:1427663
Frontiers in oncology 2024;14:1427663
The prognostic value of co-expression of stemness markers CD44 and CD133 in endometrial cancer.
Jiang P, Tian C, Zheng Y, Gong C, Wang J, Liu Y
Frontiers in oncology 2024;14:1338908
Frontiers in oncology 2024;14:1338908
Molecular glue triggers degradation of PHGDH by enhancing the interaction between DDB1 and PHGDH.
Huang Z, Zhang K, Jiang Y, Wang M, Li M, Guo Y, Gao R, Li N, Wang C, Chen J, Wang J, Liu N, Liu X, Liu S, Wei M, Yang C, Yang G
Acta pharmaceutica Sinica. B 2024 Sep;14(9):4001-4013
Acta pharmaceutica Sinica. B 2024 Sep;14(9):4001-4013
Lyophilizable Stem Cell-Hybrid Liposome with Long-Term Stability and High Targeting Capacity.
Zhang T, Zheng X, Lin R, Sun H, Wu H, Zhang J, Chen S, Li Y, Xu D, Gao J
Advanced healthcare materials 2024 Sep;13(22):e2400704
Advanced healthcare materials 2024 Sep;13(22):e2400704
Hyaluronic acid-coated polypeptide nanogel enhances specific distribution and therapy of tacrolimus in rheumatoid arthritis.
Li Y, Wang X, Gao Y, Zhang Z, Liu T, Zhang Z, Wang Y, Chang F, Yang M
Journal of nanobiotechnology 2024 Sep 6;22(1):547
Journal of nanobiotechnology 2024 Sep 6;22(1):547
Phosphatase LHPP confers prostate cancer ferroptosis activation by modulating the AKT-SKP2-ACSL4 pathway.
Xie G, Li N, Li K, Xu Y, Zhang Y, Cao S, Huang B, Liu R, Zhou P, Ding Y, Ding Y, Yang J, Jia Z, Huang Z
Cell death & disease 2024 Sep 11;15(9):665
Cell death & disease 2024 Sep 11;15(9):665
LncRNA HOTAIRM1 promotes radioresistance in nasopharyngeal carcinoma by modulating FTO acetylation-dependent alternative splicing of CD44.
Mi J, Wang Y, He S, Qin X, Li Z, Zhang T, Huang W, Wang R
Neoplasia (New York, N.Y.) 2024 Oct;56:101034
Neoplasia (New York, N.Y.) 2024 Oct;56:101034
Biomimetic nanocomplex based corneal neovascularization theranostics.
Ye J, Cheng Y, Wen X, Han Y, Wei X, Wu Y, Chen C, Su M, Cai S, Pan J, Liu G, Chu C
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:50-60
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:50-60
Exploring the prognostic value of BRMS1 + microglia based on single-cell anoikis regulator patterns in the immunologic microenvironment of GBM.
Zhao S, Ni K, Xie J, Cheng C, Zhao N, Liu J, Ji W, Wang Q, Zhang P, Liu Y
Journal of neuro-oncology 2024 Oct;170(1):101-117
Journal of neuro-oncology 2024 Oct;170(1):101-117
Downregulation of short-stature homeobox protein 2 suppresses gastric cancer cell growth and stemness in vitro and in vivo via inactivating wnt/β-catenin signaling.
Chen X, Li S, Sun B
Drug development research 2024 Nov;85(7):e70006
Drug development research 2024 Nov;85(7):e70006
Short-term usage of proton pump inhibitors during admission was associated with increased risk of rehospitalization in critically ill patients with myocardial infarction: a cohort study.
Zhu JD, Yang LJ, Zhao JN, Wang P, Li YH, Zhang XS, Pan JM, Jiang MH, Yang HY, Yin SJ, He GH
European journal of clinical pharmacology 2024 Nov;80(11):1741-1750
European journal of clinical pharmacology 2024 Nov;80(11):1741-1750
Association of the podocyte phenotype with extracapillary hypercellularity in patients with diabetic kidney disease.
Han W, Zheng Q, Zhang Z, Wang X, Gao L, Niu D, Wang X, Li R, Wang C
Journal of nephrology 2024 Nov;37(8):2209-2222
Journal of nephrology 2024 Nov;37(8):2209-2222
Dual-targeted halofuginone hydrobromide nanocomplexes for promotion of macrophage repolarization and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes in adjuvant-induced arthritis in rats.
Zhu J, Lin Y, Li G, He Y, Su Z, Tang Y, Zhang Y, Xu Q, Yao Z, Zhou H, Liu B, Cai X
Journal of pharmaceutical analysis 2024 Nov;14(11):100981
Journal of pharmaceutical analysis 2024 Nov;14(11):100981
CAFs-derived lactate enhances the cancer stemness through inhibiting the MST1 ubiquitination degradation in OSCC.
Zhang S, Wang J, Chen Y, Liang W, Liu H, Du R, Sun Y, Hu C, Shang Z
Cell & bioscience 2024 Nov 27;14(1):144
Cell & bioscience 2024 Nov 27;14(1):144
Single-cell sequencing reveals PTX3 involvement in ovarian cancer metastasis.
Liu S, Wu T, Song X, Quan L, Wang X, Liu Q, Zhou X
Journal of ovarian research 2024 Nov 23;17(1):235
Journal of ovarian research 2024 Nov 23;17(1):235
Tumor microenvironment remodeling after neoadjuvant chemoradiotherapy in local advanced rectal cancer revealed by single-cell RNA sequencing.
Su W, Ling Y, Yang X, Wu Y, Xing C
Journal of translational medicine 2024 Nov 18;22(1):1037
Journal of translational medicine 2024 Nov 18;22(1):1037
Platycodin D ameliorates polycystic ovary syndrome-induced ovarian damage by upregulating CD44 to attenuate ferroptosis.
Ji R, Wang S, Chen X, Yang Z, Zhang Z, Bao S, Xiao Z, Zhang Y, Yin T, Yang J
Free radical biology & medicine 2024 Nov 1;224:707-722
Free radical biology & medicine 2024 Nov 1;224:707-722
The involvement of epidermal growth factor receptor/protein kinase B signaling in the tumor intrinsic PD-L1-induced malignant potential of oral squamous cell carcinoma.
Sasabe E, Tomomura A, Yamamoto T
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2024 May;53(5):310-320
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2024 May;53(5):310-320
YAP maintains cartilage stem/progenitor cell homeostasis in osteoarthritis.
Zhang L, Wang X, Xia G, Huang J, Wen Z, Liang C, Cao X, Zhou Y, Wu S
Journal of orthopaedic translation 2024 May;46:79-90
Journal of orthopaedic translation 2024 May;46:79-90
Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus.
Song Y, Jiang W, Afridi SK, Wang T, Zhu F, Xu H, Nazir FH, Liu C, Wang Y, Long Y, Huang YA, Qiu W, Tang C
Cell reports 2024 May 28;43(5):114226
Cell reports 2024 May 28;43(5):114226
α5-nAChR/ADAM10 signaling mediates nicotine-related cutaneous melanoma progression via STAT3 activation.
Li X, Meng X, Fan H, Wang Y, Jia Y, Jiao J, Ma X
Archives of dermatological research 2024 May 25;316(6):269
Archives of dermatological research 2024 May 25;316(6):269
Adipose stem cells-derived small extracellular vesicles transport Thrombospondin 1 cargo to promote insulin resistance in gestational diabetes mellitus.
Li H, Yang H, Liu J, Yang H, Gao X, Yang X, Liu Z, Qian Q
Diabetology & metabolic syndrome 2024 May 19;16(1):105
Diabetology & metabolic syndrome 2024 May 19;16(1):105
Melatonin inhibits the stemness of head and neck squamous cell carcinoma by modulating HA synthesis via the FOSL1/HAS3 axis.
Luo X, Wang J, Chen Y, Zhou X, Shao Z, Liu K, Shang Z
Journal of pineal research 2024 Mar;76(2):e12940
Journal of pineal research 2024 Mar;76(2):e12940
Squalene monooxygenase facilitates bladder cancer development in part by regulating PCNA.
Zhu C, Fang X, Liu X, Jiang C, Ren W, Huang W, Jiang Y, Wang D
Biochimica et biophysica acta. Molecular cell research 2024 Mar;1871(3):119681
Biochimica et biophysica acta. Molecular cell research 2024 Mar;1871(3):119681
ZNF217-activated Notch signaling mediates sulforaphane-suppressed stem cell properties in colorectal cancer.
Wang M, Tang L, Chen S, Wang L, Wu J, Zhong C, Li Y, Chen Y
The Journal of nutritional biochemistry 2024 Mar;125:109551
The Journal of nutritional biochemistry 2024 Mar;125:109551
Hinokitiol Inhibits Breast Cancer Cells In Vitro Stemness-Progression and Self-Renewal with Apoptosis and Autophagy Modulation via the CD44/Nanog/SOX2/Oct4 Pathway.
Chiang YF, Huang KC, Chen HY, Hamdy NM, Huang TC, Chang HY, Shieh TM, Huang YJ, Hsia SM
International journal of molecular sciences 2024 Mar 31;25(7)
International journal of molecular sciences 2024 Mar 31;25(7)
Mechanism of Porphyra Yezoensis Polysaccharides in Inhibiting Hyperoxalate-Induced Renal Injury and Crystal Deposition.
Deng JW, Li CY, Huang YP, Liu WF, Zhang Q, Long J, Wu WQ, Huang LH, Zeng GH, Sun XY
Journal of agricultural and food chemistry 2024 Mar 27;72(12):6372-6388
Journal of agricultural and food chemistry 2024 Mar 27;72(12):6372-6388
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
Lv L, Wei Q, Zhang J, Dong Y, Shan Z, Chang N, Zhao Y, Bian P, Yi Q
Cellular & molecular biology letters 2024 Mar 19;29(1):39
Cellular & molecular biology letters 2024 Mar 19;29(1):39
EphA2 promotes the transcription of KLF4 to facilitate stemness in oral squamous cell carcinoma.
Bai J, Chen Y, Sun Y, Wang X, Wang Y, Guo S, Shang Z, Shao Z
Cellular and molecular life sciences : CMLS 2024 Jun 25;81(1):278
Cellular and molecular life sciences : CMLS 2024 Jun 25;81(1):278
Hypomethylation-enhanced CRTC2 expression drives malignant phenotypes and primary resistance to immunotherapy in hepatocellular carcinoma.
Zhang R, Dai J, Yao F, Zhou S, Huang W, Xu J, Yu K, Chen Y, Fan B, Zhang L, Xu J, Li Q
iScience 2024 Jun 21;27(6):109821
iScience 2024 Jun 21;27(6):109821
RANKL/RANK signaling recruits Tregs via the CCL20-CCR6 pathway and promotes stemness and metastasis in colorectal cancer.
Ouyang J, Hu S, Zhu Q, Li C, Kang T, Xie W, Wang Y, Li Y, Lu Y, Qi J, Xia M, Chen J, Yang Y, Sun Y, Gao T, Ye L, Liang Q, Pan Y, Zhu C
Cell death & disease 2024 Jun 20;15(6):437
Cell death & disease 2024 Jun 20;15(6):437
Huaier enhances the tumor-killing effect and reverses gemcitabine-induced stemness by suppressing FoxM1.
Wang Q, Gong M, Liu R, Mo J, Bai R, An R, Wang X, Han L, Wang Z, Ma Q, Wu Z, Zhou C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155656
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155656
Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues.
Wu J, Wang C, Sun S, Ren T, Pan L, Liu H, Hou S, Wu S, Yan X, Zhang J, Zhao X, Liu W, Zhu S, Wei S, Zhang C, Jia X, Zhang Q, Yu Z, Zhuo Y, Zhao Q, Yang C, Wang N
Protein & cell 2024 Jul 20;15(8):594-611
Protein & cell 2024 Jul 20;15(8):594-611
The demethylase ALKBH5 mediates ZKSCAN3 expression through the m(6)A modification to activate VEGFA transcription and thus participates in MNNG-induced gastric cancer progression.
Wang Q, Huang Y, Jiang M, Tang Y, Wang Q, Bai L, Yu C, Yang X, Ding K, Wang W, Bai J, Chen Y
Journal of hazardous materials 2024 Jul 15;473:134690
Journal of hazardous materials 2024 Jul 15;473:134690
Spatiotemporally sequential delivery of biomimetic liposomes potentiates glioma chemotherapy.
Zhou M, Wu Y, Sun M, Qin Y, Zhao J, Qiu Z, Li C, Zhang Y, Xiong Y, Shen Y, Zou Z, Tu J, Shen W, Sun C
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:876-888
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:876-888
Engineering of targeting antioxidant polypeptide nanopolyplexes for the treatment of acute lung injury.
Li YX, Bao YT, Hu JB
International journal of biological macromolecules 2024 Jan;254(Pt 3):127872
International journal of biological macromolecules 2024 Jan;254(Pt 3):127872
Combining microfluidic chip and low-attachment culture devices to isolate oral cancer stem cells.
Chen HH, Nguyen TV, Shih YH, Chang KC, Chiu KC, Hsia SM, Fuh LJ, Shieh TM
Journal of dental sciences 2024 Jan;19(1):560-567
Journal of dental sciences 2024 Jan;19(1):560-567
BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma.
Feng Y, Cai L, Pook M, Liu F, Chang CH, Mouti MA, Nibhani R, Militi S, Dunford J, Philpott M, Fan Y, Fan GC, Liu Q, Qi J, Wang C, Hong W, Morgan H, Wang M, Sadayappan S, Jegga AG, Oppermann U, Wang Y, Huang W, Jiang L, Pauklin S
Gastroenterology 2024 Jan;166(1):139-154
Gastroenterology 2024 Jan;166(1):139-154
Oxidized ATM governs stemness of breast cancer stem cell through regulating ubiquitylation and acetylation switch.
Zhou X, Liu X, Wan X, Xu M, Wang R, Yang D, Peng M, Jin T, Tang R, Liu M, Hou Y
Biochemical and biophysical research communications 2024 Jan 8;691:149243
Biochemical and biophysical research communications 2024 Jan 8;691:149243
Near-infrared-responsive GE11-CuS@Gal nanoparticles as an intelligent drug release system for targeting therapy against oral squamous cell carcinoma.
Lan Q, Wang S, Chen Z, Hua J, Hu J, Luo S, Xu Y
International journal of pharmaceutics 2024 Jan 5;649:123667
International journal of pharmaceutics 2024 Jan 5;649:123667
Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway.
Jin H, Liu C, Liu X, Wang H, Zhang Y, Liu Y, Li J, Yu Z, Liu HX
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117270
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117270
Microscopic clusters feature the composition of biochemical tetraspanin-assemblies and constitute building-blocks of tetraspanin enriched domains.
Schmidt SC, Massenberg A, Homsi Y, Sons D, Lang T
Scientific reports 2024 Jan 24;14(1):2093
Scientific reports 2024 Jan 24;14(1):2093
Combining transcriptomics and network pharmacology to reveal the mechanism of Zuojin capsule improving spasmolytic polypeptide-expressing metaplasia.
Xiong M, Chen X, Wang H, Tang X, Wang Q, Li X, Ma H, Ye X
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117075
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117075
PLEK2 mediates metastasis and invasion via α5-nAChR activation in nicotine-induced lung adenocarcinoma.
Li Q, Li J, Wang J, Wang J, Lu T, Jia Y, Sun H, Ma X
Molecular carcinogenesis 2024 Feb;63(2):253-265
Molecular carcinogenesis 2024 Feb;63(2):253-265
UDP-glucose dehydrogenase supports autophagy-deficient PDAC growth via increasing hyaluronic acid biosynthesis.
Fan M, Huo S, Guo Y, Wang R, Hao W, Zhang Z, Wang L, Zhao Y
Cell reports 2024 Feb 27;43(2):113808
Cell reports 2024 Feb 27;43(2):113808
In-situ gelation of fibrin gel encapsulating platelet-rich plasma-derived exosomes promotes rotator cuff healing.
Li M, Shi L, Chen X, Yi D, Ding Y, Chen J, Xing G, Chen S, Wang L, Zhang Y, Zhu Y, Wang Y
Communications biology 2024 Feb 20;7(1):205
Communications biology 2024 Feb 20;7(1):205
Molecular Mechanisms of Intracellular Delivery of Nanoparticles Monitored by an Enzyme-Induced Proximity Labeling.
Ren J, Zhang Z, Geng S, Cheng Y, Han H, Fan Z, Dai W, Zhang H, Wang X, Zhang Q, He B
Nano-micro letters 2024 Feb 1;16(1):103
Nano-micro letters 2024 Feb 1;16(1):103
Regulatory roles of NAMPT and NAD(+) metabolism in uterine leiomyoma progression: Implications for ECM accumulation, stemness, and microenvironment.
Chiang YF, Huang KC, Huang TC, Chen HY, Ali M, Al-Hendy A, Huang PS, Hsia SM
Redox biology 2024 Dec;78:103411
Redox biology 2024 Dec;78:103411
Effects of sulforaphane on prostate cancer stem cells-like properties: In vitro and molecular docking studies.
Xuan Y, Xu J, Que H, Zhu J
Archives of biochemistry and biophysics 2024 Dec;762:110216
Archives of biochemistry and biophysics 2024 Dec;762:110216
Rosmarinic acid attenuates glioblastoma cells and spheroids' growth and EMT/stem-like state by PTEN/PI3K/AKT downregulation and ERK-induced apoptosis.
Şengelen A, Önay-Uçar E
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156060
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156060
Luoshi Neiyi Prescription inhibits estradiol synthesis and inflammation in endometriosis through the HIF1A/EZH2/SF-1 pathway.
Wu L, Lan D, Sun B, Su R, Pei F, Kuang Z, Su Y, Lin S, Wang X, Zhang S, Chen X, Jia J, Zeng C
Journal of ethnopharmacology 2024 Dec 5;335:118659
Journal of ethnopharmacology 2024 Dec 5;335:118659
Hyaluronic acid-modified extracellular vesicles for targeted doxorubicin delivery in hepatocellular carcinoma.
Liu Y, Hinnant B, Chen S, Tao H, Huang Z, Qian M, Zhou M, Han Z, Han ZC, Zhang J, Li Z
Experimental cell research 2024 Dec 1;443(2):114332
Experimental cell research 2024 Dec 1;443(2):114332
YAP/TAZ-TEAD activity promotes the malignant transformation of cervical intraepithelial neoplasia through enhancing the characteristics and Warburg effect of cancer stem cells.
Li S, Li X, Yang YB, Wu SF
Apoptosis : an international journal on programmed cell death 2024 Aug;29(7-8):1198-1210
Apoptosis : an international journal on programmed cell death 2024 Aug;29(7-8):1198-1210
Identifying polyamine related biomarkers in diagnosis and treatment of ulcerative colitis by integrating bulk and single-cell sequencing data.
Wei W, Lu Y, Zhang M, Guo J, Zhang H
Scientific reports 2024 Aug 5;14(1):18094
Scientific reports 2024 Aug 5;14(1):18094
Promotion of hepatocellular carcinoma stemness and progression by abnormal spindle-like microcephaly-associated protein via the Wnt/β-catenin pathway.
Li GJ, Xiang Y, Yang JY, Weiskirchen R, Feng R, Zhai WL
Journal of gastrointestinal oncology 2024 Aug 31;15(4):1613-1626
Journal of gastrointestinal oncology 2024 Aug 31;15(4):1613-1626
Homologous Tumor Cell-Derived Biomimetic Nano-Trojan Horse Integrating Chemotherapy with Genetherapy for Boosting Triple-Negative Breast Cancer Therapy.
Duan W, Shen Q, Ju L, Huang Z, Geng J, Wu Q, Yu C, Wei J
ACS applied materials & interfaces 2024 Aug 28;16(34):45523-45536
ACS applied materials & interfaces 2024 Aug 28;16(34):45523-45536
A human fetal cerebellar map of the late second trimester reveals developmental molecular characteristics and abnormality in trisomy 21.
Yu H, Liu Y, Xu F, Fu Y, Yang M, Ding L, Wu Y, Tang F, Qiao J, Wen L
Cell reports 2024 Aug 27;43(8):114586
Cell reports 2024 Aug 27;43(8):114586
Early rhombic lip Protogenin(+ve) stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma.
Visvanathan A, Saulnier O, Chen C, Haldipur P, Orisme W, Delaidelli A, Shin S, Millman J, Bryant A, Abeysundara N, Wu X, Hendrikse LD, Patil V, Bashardanesh Z, Golser J, Livingston BG, Nakashima T, Funakoshi Y, Ong W, Rasnitsyn A, Aldinger KA, Richman CM, Van Ommeren R, Lee JJY, Ly M, Vladoiu MC, Kharas K, Balin P, Erickson AW, Fong V, Zhang J, Suárez RA, Wang H, Huang N, Pallota JG, Douglas T, Haapasalo J, Razavi F, Silvestri E, Sirbu O, Worme S, Kameda-Smith MM, Wu X, Daniels C, MichaelRaj AK, Bhaduri A, Schramek D, Suzuki H, Garzia L, Ahmed N, Kleinman CL, Stein LD, Dirks P, Dunham C, Jabado N, Rich JN, Li W, Sorensen PH, Wechsler-Reya RJ, Weiss WA, Millen KJ, Ellison DW, Dimitrov DS, Taylor MD
Cell 2024 Aug 22;187(17):4733-4750.e26
Cell 2024 Aug 22;187(17):4733-4750.e26
tsRNA-GlyGCC promotes colorectal cancer progression and 5-FU resistance by regulating SPIB.
Xu R, Du A, Deng X, Du W, Zhang K, Li J, Lu Y, Wei X, Yang Q, Tang H
Journal of experimental & clinical cancer research : CR 2024 Aug 17;43(1):230
Journal of experimental & clinical cancer research : CR 2024 Aug 17;43(1):230
Inhibiting CD44-ICD Attenuates LPS-Induced Initiation of Hepatic Inflammation in Septic Mice.
Li LH, Hsu DZ, Chandrasekaran VRM, Liu MY
International journal of molecular sciences 2024 Aug 15;25(16)
International journal of molecular sciences 2024 Aug 15;25(16)
LOXL2-induced PEAR1 Ser891 phosphorylation suppresses CD44 degradation and promotes triple-negative breast cancer metastasis.
Shen Y, Yan J, Li L, Sun H, Zhang L, Li G, Wang X, Liu R, Wu X, Han B, Sun X, Liu J, Fan X
The Journal of clinical investigation 2024 Aug 15;134(16)
The Journal of clinical investigation 2024 Aug 15;134(16)
Biomineralization-Tuned Nanounits Reprogram the Signal Transducer and Activator of Transcription 3 Signaling for Ferroptosis-Immunotherapy in Cancer Stem Cells.
Zhao Y, Fei Y, Zhao Y, Li M, Hu Y, Cai K, Yu SH, Luo Z
ACS nano 2024 Aug 13;18(32):21268-21287
ACS nano 2024 Aug 13;18(32):21268-21287
H3K18 lactylation-mediated VCAM1 expression promotes gastric cancer progression and metastasis via AKT-mTOR-CXCL1 axis.
Zhao Y, Jiang J, Zhou P, Deng K, Liu Z, Yang M, Yang X, Li J, Li R, Xia J
Biochemical pharmacology 2024 Apr;222:116120
Biochemical pharmacology 2024 Apr;222:116120
Mesothelin-based CAR-T cells exhibit potent antitumor activity against ovarian cancer.
Guo J, Zeng X, Zhu Y, Yang D, Zhao X
Journal of translational medicine 2024 Apr 18;22(1):367
Journal of translational medicine 2024 Apr 18;22(1):367
Dysregulation of neuroprotective lipoxin pathway in astrocytes in response to cytokines and ocular hypertension.
Karnam S, Maurya S, Ng E, Choudhary A, Thobani A, Flanagan JG, Gronert K
Acta neuropathologica communications 2024 Apr 12;12(1):58
Acta neuropathologica communications 2024 Apr 12;12(1):58
A chemo/chemodynamic nanoparticle based on hyaluronic acid induces ferroptosis and apoptosis for triple-negative breast cancer therapy.
Wang N, Zhang Q, Wang Z, Liu Y, Yang S, Zhao X, Peng J
Carbohydrate polymers 2024 Apr 1;329:121795
Carbohydrate polymers 2024 Apr 1;329:121795
Sulforaphane Suppresses MCF-7 Breast Cancer Cells Growth via miR-19/PTEN Axis to Antagonize the Effect of Butyl Benzyl Phthalate.
Cao W, Lu X, Zhong C, Wu J
Nutrition and cancer 2023;75(3):980-991
Nutrition and cancer 2023;75(3):980-991
Diallyl Trisulfide Suppresses the Renal Cancer Stem-like Cell Properties via Nanog.
Zhang T, Cao W, Sun H, Yu D, Zhong C
Nutrition and cancer 2023;75(3):971-979
Nutrition and cancer 2023;75(3):971-979
Protective Effect of Alkaline Mineral Water on Calcium Oxalate-Induced Kidney Injury in Mice.
Liu L, Lin C, Li X, Cheng Y, Wang R, Luo C, Zhao X, Jiang Z
Evidence-based complementary and alternative medicine : eCAM 2023;2023:4559802
Evidence-based complementary and alternative medicine : eCAM 2023;2023:4559802
Extracellular vesicles carrying miR-6836 derived from resistant tumor cells transfer cisplatin resistance of epithelial ovarian cancer via DLG2-YAP1 signaling pathway.
Zou Y, Zhao Z, Wang J, Ma L, Liu Y, Sun L, Song Y
International journal of biological sciences 2023;19(10):3099-3114
International journal of biological sciences 2023;19(10):3099-3114
FAK downregulation suppresses stem-like properties and migration of human colorectal cancer cells.
Xu C, Zhang W, Liu C
PloS one 2023;18(4):e0284871
PloS one 2023;18(4):e0284871
Decoding the Intercellular Cross-Talking Between Immune Cells and Renal Innate Cells in Diabetic Kidney Disease by Bioinformatics.
Zhou M, Lu F, Jiang L, Chen C, Chen S, Geng L, Sun R, Li Q, Duan S, Zhang B, Mao H, Xing C, Yuan Y
Journal of inflammation research 2023;16:3049-3062
Journal of inflammation research 2023;16:3049-3062
RUNX1/CD44 axis regulates the proliferation, migration, and immunotherapy of gliomas: A single-cell sequencing analysis.
Zhang H, Cao H, Luo H, Zhang N, Wang Z, Dai Z, Wu W, Liu G, Xie Z, Cheng Q, Cheng Y
Frontiers in immunology 2023;14:1086280
Frontiers in immunology 2023;14:1086280
Inhibition of Na+/H+ exchanger (NHE) 7 by 5-(N-ethyl-N-isopropyl)-Amiloride displays anti-cancer activity in non-small cell lung cancer by disrupting cancer stem cell activity and downregulating PD-L1 expression.
Wang BY, Shen HT, Lee YL, Chien PJ, Chang WW
American journal of cancer research 2023;13(10):4721-4733
American journal of cancer research 2023;13(10):4721-4733
Vitamin D inhibits osteosarcoma by reprogramming nonsense-mediated RNA decay and SNAI2-mediated epithelial-to-mesenchymal transition.
Capobianco E, McGaughey V, Seraphin G, Heckel J, Rieger S, Lisse TS
Frontiers in oncology 2023;13:1188641
Frontiers in oncology 2023;13:1188641
YAP1 affects the prognosis through the regulation of stemness in endometrial cancer.
Kong W, Huang Y, Jiang P, Tu Y, Li N, Wang J, Zhou Q, Zheng Y, Gou S, Tian C, Yuan R
PeerJ 2023;11:e15891
PeerJ 2023;11:e15891
Radiated tumor cell-derived microparticles effectively kill stem-like tumor cells by increasing reactive oxygen species.
Hu Y, Wan C, Yang X, Tian Y, Deng S, An D, Wang Y, Wang J, Liao Z, Meng J, Qin Y, Sun Y, Yang K
Frontiers in bioengineering and biotechnology 2023;11:1156951
Frontiers in bioengineering and biotechnology 2023;11:1156951
A novel TOX3-WDR5-ABCG2 signaling axis regulates the progression of colorectal cancer by accelerating stem-like traits and chemoresistance.
Hao J, Huang J, Hua C, Zuo Y, Yu W, Wu X, Li L, Xue G, Wan X, Ru L, Guo Z, Han S, Deng W, Lin F, Guo W
PLoS biology 2023 Sep;21(9):e3002256
PLoS biology 2023 Sep;21(9):e3002256
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
Zhao X, Guo B, Sun W, Yu J, Cui L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2206878
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2206878
CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance.
Takasugi M, Ohtani N, Takemura K, Emmrich S, Zakusilo FT, Yoshida Y, Kutsukake N, Mariani JN, Windrem MS, Chandler-Militello D, Goldman SA, Satoh J, Ito S, Seluanov A, Gorbunova V
Cell reports 2023 Sep 26;42(9):113130
Cell reports 2023 Sep 26;42(9):113130
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
Hong SY, Yang YY, Wang SG, Qin BL
Chemico-biological interactions 2023 Sep 1;382:110636
Chemico-biological interactions 2023 Sep 1;382:110636
SEC61 translocon subunit gamma enhances low-dose cisplatin-induced cancer-stem cell properties of head and neck squamous cell carcinoma via enhancing Ca(2+)-mediated autophagy.
Bu X, Zhang J, Sun H, Wang W, Ma X, Sun L
Journal of dental sciences 2023 Oct;18(4):1685-1692
Journal of dental sciences 2023 Oct;18(4):1685-1692
The PRX-1/TLR4 axis promotes hypoxia-induced radiotherapy resistance in non-small cell lung cancer by targeting the NF-κB/p65 pathway.
Hao J, Song Z, Su J, Li L, Zou L, Zou K
Cellular signalling 2023 Oct;110:110806
Cellular signalling 2023 Oct;110:110806
Fabrication of a Three-Dimensional Spheroid Culture System for Oral Squamous Cell Carcinomas Using a Microfabricated Device.
Ikeda-Motonakano R, Hirabayashi-Nishimuta F, Yada N, Yamasaki R, Nagai-Yoshioka Y, Usui M, Nakazawa K, Yoshiga D, Yoshioka I, Ariyoshi W
Cancers 2023 Oct 26;15(21)
Cancers 2023 Oct 26;15(21)
Dysregulation of Neuroprotective Lipoxin Pathway in Astrocytes in Response to Cytokines and Ocular Hypertension.
Karnam S, Maurya S, Ng E, Choudhary A, Thobani A, Flanagan JG, Gronert K
bioRxiv : the preprint server for biology 2023 Oct 2;
bioRxiv : the preprint server for biology 2023 Oct 2;
Histone acetyltransferase CSRP2BP promotes the epithelial-mesenchymal transition and metastasis of cervical cancer cells by activating N-cadherin.
Yang X, Sun F, Gao Y, Li M, Liu M, Wei Y, Jie Q, Wang Y, Mei J, Mei J, Ma L, Shi Y, Chen M, Li Y, Li Q, Liu M, Ma Y
Journal of experimental & clinical cancer research : CR 2023 Oct 17;42(1):268
Journal of experimental & clinical cancer research : CR 2023 Oct 17;42(1):268
Diallyl trisulfide inhibits gastric cancer stem cell properties through ΔNp63/sonic hedgehog pathway.
Ge M, Zhu J, Yi K, Chen Y, Cao W, Wang M, Xie C, Li X, Geng S, Wu J, Zhong C, Cao H, Jiang Z, Han H
Molecular carcinogenesis 2023 Nov;62(11):1673-1685
Molecular carcinogenesis 2023 Nov;62(11):1673-1685
Single-Cell RNA Sequencing of Coronary Perivascular Adipose Tissue From End-Stage Heart Failure Patients Identifies SPP1(+) Macrophage Subpopulation as a Target for Alleviating Fibrosis.
Fu M, Shu S, Peng Z, Liu X, Chen X, Zeng Z, Yang Y, Cui H, Zhao R, Wang X, Du L, Wu M, Feng W, Song J
Arteriosclerosis, thrombosis, and vascular biology 2023 Nov;43(11):2143-2164
Arteriosclerosis, thrombosis, and vascular biology 2023 Nov;43(11):2143-2164
Hyaluronan decorated layer-by-layer assembled lipid nanoparticles for miR-181a delivery in glioblastoma treatment.
Passos Gibson V, Tahiri H, Yang C, Phan QT, Banquy X, Hardy P
Biomaterials 2023 Nov;302:122341
Biomaterials 2023 Nov;302:122341
Hyaluronan-CD44 Interaction Regulates Mouse Retinal Progenitor Cells Migration, Proliferation and Neuronal Differentiation.
Ma J, Fang X, Chen M, Wang Y, Zhang L
Stem cell reviews and reports 2023 Nov;19(8):2929-2942
Stem cell reviews and reports 2023 Nov;19(8):2929-2942
Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy.
Xiao C, Sun Y, Fan J, Nguyen W, Chen S, Long Y, Chen W, Zhu A, Liu B
Acta pharmaceutica Sinica. B 2023 Nov;13(11):4591-4606
Acta pharmaceutica Sinica. B 2023 Nov;13(11):4591-4606
Black Phosphorus as a Targeting PPAR-γ Agonist to Reverse Chemoresistance in Patient-derived Organoids, Mice, and Pancreatic Tumor Cells.
Jiang S, Liu W, Shi D, Cheng H, Deng T, Chen G, Ma L, Zhang X, Gong P
Advanced healthcare materials 2023 Nov;12(29):e2301324
Advanced healthcare materials 2023 Nov;12(29):e2301324
The Critical Role of The Piezo1/β-catenin/ATF4 Axis on The Stemness of Gli1(+) BMSCs During Simulated Microgravity-Induced Bone Loss.
Hu Y, Tian H, Chen W, Liu Y, Cao Y, Pei H, Ming C, Shan C, Chen X, Dai Z, Yang S, Shao Z, Lan S, Liu Y, Tong W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2303375
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2303375
Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma.
Thirant C, Peltier A, Durand S, Kramdi A, Louis-Brennetot C, Pierre-Eugène C, Gautier M, Costa A, Grelier A, Zaïdi S, Gruel N, Jimenez I, Lapouble E, Pierron G, Sitbon D, Brisse HJ, Gauthier A, Fréneaux P, Grossetête S, Baudrin LG, Raynal V, Baulande S, Bellini A, Bhalshankar J, Carcaboso AM, Geoerger B, Rohrer H, Surdez D, Boeva V, Schleiermacher G, Delattre O, Janoueix-Lerosey I
Nature communications 2023 May 4;14(1):2575
Nature communications 2023 May 4;14(1):2575
Exosomes obtained from adipose mesenchymal stem cells prevent ischemia-reperfusion injury after torsion-detorsion in rat testes.
Şimşek FB, Şencan A, Vatansever HS
Pediatric surgery international 2023 May 24;39(1):204
Pediatric surgery international 2023 May 24;39(1):204
METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3.
Hu B, Zou X, Yu Y, Jiang Y, Xu H
Regenerative therapy 2023 Mar;22:148-159
Regenerative therapy 2023 Mar;22:148-159
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
Gai C, Zhao Y, Xin D, Li T, Cheng Y, Jiang Z, Song Y, Liu D, Wang Z
Cells 2023 Mar 9;12(6)
Cells 2023 Mar 9;12(6)
EGFRvIII Promotes the Proneural-Mesenchymal Transition of Glioblastoma Multiforme and Reduces Its Sensitivity to Temozolomide by Regulating the NF-κB/ALDH1A3 Axis.
Shi ZF, Li GZ, Zhai Y, Pan CQ, Wang D, Yu MC, Liu C, Zhang W, Yu XG
Genes 2023 Mar 4;14(3)
Genes 2023 Mar 4;14(3)
Low-dose phthalates promote breast cancer stem cell properties via the oncogene ΔNp63α and the Sonic hedgehog pathway.
Cao WS, Zhao MJ, Chen Y, Zhu JY, Xie CF, Li XT, Geng SS, Zhong CY, Fu JY, Wu JS
Ecotoxicology and environmental safety 2023 Mar 1;252:114605
Ecotoxicology and environmental safety 2023 Mar 1;252:114605
Accelerate wound healing by microscale gel array patch encapsulating defined SDF-1α gradient.
Xu Z, Wu J, Gong P, Chang C
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:1-12
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:1-12
Human amniotic mesenchymal stem cell-conditioned medium inhibited LPS-induced cell injury and inflammation by modulating CD14/TLR4-mediated signaling pathway in monocytes.
Li M, Li T, Jin J, Xie C, Zhu J
Molecular immunology 2023 Jun;158:10-21
Molecular immunology 2023 Jun;158:10-21
Integrated analysis based on vesicle trafficking-related genes identifying CNIH4 as a novel therapeutic target for glioma.
Fang Z, Kong F, Zeng J, Zhang Z, Wang Y, Wang Y, Duan J, Chen L, Wang J, Liu F
Cancer medicine 2023 Jun;12(11):12943-12959
Cancer medicine 2023 Jun;12(11):12943-12959
MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4.
Wang R, Yu W, Zhu T, Lin F, Hua C, Ru L, Guo P, Wan X, Xue G, Guo Z, Han S, Lv K, Zhang G, Ge H, Guo W, Xu L, Deng W
Cancer science 2023 Jun;114(6):2277-2292
Cancer science 2023 Jun;114(6):2277-2292
LIMP-2 enhances cancer stem-like cell properties by promoting autophagy-induced GSK3β degradation in head and neck squamous cell carcinoma.
Liu Y, Li S, Wang S, Yang Q, Wu Z, Zhang M, Chen L, Sun Z
International journal of oral science 2023 Jun 8;15(1):24
International journal of oral science 2023 Jun 8;15(1):24
Identification of Piezo1 as a potential target for therapy of colon cancer stem-like cells.
Li R, Wang D, Li H, Lei X, Liao W, Liu XY
Discover oncology 2023 Jun 12;14(1):95
Discover oncology 2023 Jun 12;14(1):95
Placental homing peptide guides HIF1α‑silenced exosomes conjugates for targeted enhancement of invasion of trophoblast cells.
Chen F, Cen H, Mao D, Feng R
Molecular medicine reports 2023 Jul;28(1)
Molecular medicine reports 2023 Jul;28(1)
Engineering a facile and versatile nanoplatform to facilitate the delivery of multiple agents for targeted breast cancer chemo-immunotherapy.
Bahreyni A, Mohamud Y, Zhang J, Luo H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114789
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114789
USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST1.
Chen J, Wu Z, Deng W, Tang M, Wu L, Lin N, Chen L, Fu Y, Zhao M, Chen C, Li W
Journal of translational medicine 2023 Jul 8;21(1):453
Journal of translational medicine 2023 Jul 8;21(1):453
CD44 targeted indirubin nanocrystal-loaded hyaluronic acid hydrogel for the treatment of psoriasis.
Li L, Liu C, Fu J, Wang Y, Yang D, Peng B, Liu X, Han X, Meng Y, Feng F, Hu X, Qi C, Wang Y, Zheng Y, Li P
International journal of biological macromolecules 2023 Jul 15;243:125239
International journal of biological macromolecules 2023 Jul 15;243:125239
Effects of non-steroidal anti-inflammatory drug (ibuprofen) in low and high dose on stemness and biological characteristics of human dental pulp-derived mesenchymal stem cells.
Salkın H, Basaran KE
Connective tissue research 2023 Jan;64(1):14-25
Connective tissue research 2023 Jan;64(1):14-25
CD166-specific CAR-T cells potently target colorectal cancer cells.
He S, Li S, Guo J, Zeng X, Liang D, Zhu Y, Li Y, Yang D, Zhao X
Translational oncology 2023 Jan;27:101575
Translational oncology 2023 Jan;27:101575
Emodin reverses resistance to gemcitabine in pancreatic cancer by suppressing stemness through regulation of the epithelial‑mesenchymal transition.
Wei W, Wang J, Hu Y, Chen S, Liu J
Experimental and therapeutic medicine 2023 Jan;25(1):7
Experimental and therapeutic medicine 2023 Jan;25(1):7
3D Gelatin Microsphere Scaffolds Promote Functional Recovery after Spinal Cord Hemisection in Rats.
Ke H, Yang H, Zhao Y, Li T, Xin D, Gai C, Jiang Z, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(3):e2204528
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(3):e2204528
Sodium Butyrate Induces CRC Cell Ferroptosis via the CD44/SLC7A11 Pathway and Exhibits a Synergistic Therapeutic Effect with Erastin.
Bian Z, Sun X, Liu L, Qin Y, Zhang Q, Liu H, Mao L, Sun S
Cancers 2023 Jan 9;15(2)
Cancers 2023 Jan 9;15(2)
Sandwich Biomimetic Scaffold Based Tendon Stem/Progenitor Cell Alignment in a 3D Microenvironment for Functional Tendon Regeneration.
Li S, Sun Y, Chen Y, Lu J, Jiang G, Yu K, Wu Y, Mao Y, Jin H, Luo J, Dong S, Hu B, Ding Y, Liu A, Shen Y, Feng G, Yan S, He Y, Yan R
ACS applied materials & interfaces 2023 Jan 25;15(3):4652-4667
ACS applied materials & interfaces 2023 Jan 25;15(3):4652-4667
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection.
Ayyar BV, Ettayebi K, Salmen W, Karandikar UC, Neill FH, Tenge VR, Crawford SE, Bieberich E, Prasad BVV, Atmar RL, Estes MK
Nature communications 2023 Feb 28;14(1):1148
Nature communications 2023 Feb 28;14(1):1148
Leucine rich repeat containing 32 accelerates tenogenic differentiation of tendon-derived stem cells and promotes Achilles tendon repair in rats.
Kang K, Cui L, Zhang Q, Gao S
Experimental animals 2023 Feb 21;72(1):9-18
Experimental animals 2023 Feb 21;72(1):9-18
Macrophage-derived GPNMB trapped by fibrotic extracellular matrix promotes pulmonary fibrosis.
Wang J, Zhang X, Long M, Yuan M, Yin J, Luo W, Wang S, Cai Y, Jiang W, Chao J
Communications biology 2023 Feb 2;6(1):136
Communications biology 2023 Feb 2;6(1):136
Apoptotic tumor cell-derived microparticles loading Napabucasin inhibit CSCs and synergistic immune therapy.
Jing B, Guo F, An R, Gao Y, Li Y, Xie Y, Wang J, Chen Y, Li H, Gao T, Jin Q, Zhang L, Xie M
Journal of nanobiotechnology 2023 Feb 2;21(1):37
Journal of nanobiotechnology 2023 Feb 2;21(1):37
Integrating a phenotypic screening with a structural simplification strategy to identify 4-phenoxy-quinoline derivatives to potently disrupt the mitotic localization of Aurora kinase B.
Lv G, Shi Q, Zhang T, Li J, Long Y, Zhang W, Choudhry N, Yang K, Li H, Kalashova J, Yang C, Zhou X, Reddy MC, Anantoju KK, Zhang S, Zhang J, Allen TD, Liu H, Nimishetti N, Yang D
Bioorganic & medicinal chemistry 2023 Feb 15;80:117173
Bioorganic & medicinal chemistry 2023 Feb 15;80:117173
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Cui L, Lu Y, Zheng J, Guo B, Zhao X
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Biodegradable nano black phosphorus based SDF1-α delivery system ameliorates Erectile Dysfunction in a cavernous nerve injury rat model by recruiting endogenous stem/progenitor cells.
Fu Q, Song L, Li J, Yi B, Huang Y, Zhang Z, Xin Z, Zhu J
Journal of nanobiotechnology 2023 Dec 18;21(1):487
Journal of nanobiotechnology 2023 Dec 18;21(1):487
Dipeptidase‑2 is a prognostic marker in lung adenocarcinoma that is correlated with its sensitivity to cisplatin.
Wang Y, Zhang T, Du H, Yang M, Xie G, Liu T, Deng S, Yuan W, He S, Wu D, Xu Y
Oncology reports 2023 Aug;50(2)
Oncology reports 2023 Aug;50(2)
CD44 Drives M1 Macrophage Polarization in Diabetic Retinopathy.
Pan Z, Zhao Y, Zhou S, Wang J, Fan F
Current eye research 2023 Aug;48(8):770-780
Current eye research 2023 Aug;48(8):770-780
CD44 expression is correlated with osteosarcoma cell progression and immune infiltration and affects the Wnt/β-catenin signaling pathway.
Ji H, Kong L, Wang Y, Hou Z, Kong W, Qi J, Jin Y
Journal of bone oncology 2023 Aug;41:100487
Journal of bone oncology 2023 Aug;41:100487
B7-H3 confers stemness characteristics to gastric cancer cells by promoting glutathione metabolism through AKT/pAKT/Nrf2 pathway.
Xia L, Chen Y, Li J, Wang J, Shen K, Zhao A, Jin H, Zhang G, Xi Q, Xia S, Shi T, Li R
Chinese medical journal 2023 Aug 20;136(16):1977-1989
Chinese medical journal 2023 Aug 20;136(16):1977-1989
Hyperthermia-triggered biomimetic bubble nanomachines.
Gao J, Qin H, Wang F, Liu L, Tian H, Wang H, Wang S, Ou J, Ye Y, Peng F, Tu Y
Nature communications 2023 Aug 11;14(1):4867
Nature communications 2023 Aug 11;14(1):4867
Exosome miR-3184-5p inhibits gastric cancer growth by targeting XBP1 to regulate the AKT, STAT3, and IRE1 signalling pathways.
Lin S, Que Y, Que C, Li F, Deng M, Xu D
Asia-Pacific journal of clinical oncology 2023 Apr;19(2):e27-e38
Asia-Pacific journal of clinical oncology 2023 Apr;19(2):e27-e38
Preoperative administration of a biomimetic platelet nanodrug enhances postoperative drug delivery by bypassing thrombus.
Ji J, Lian W, Zhang Y, Lin D, Wang J, Mo Y, Xu X, Hou C, Ma C, Zheng Y, Chen J, Zhong J, Zhang F, Ke Y, Chen H
International journal of pharmaceutics 2023 Apr 5;636:122851
International journal of pharmaceutics 2023 Apr 5;636:122851
EMT-activated secretory and endocytic vesicular trafficking programs underlie a vulnerability to PI4K2A antagonism in lung cancer.
Tan X, Xiao GY, Wang S, Shi L, Zhao Y, Liu X, Yu J, Russell WK, Creighton CJ, Kurie JM
The Journal of clinical investigation 2023 Apr 3;133(7)
The Journal of clinical investigation 2023 Apr 3;133(7)
Organoids From Mucinous Appendiceal Adenocarcinomas as High-Fidelity Models for Individual Therapy.
Liu G, Xiao X, Xia Y, Huang W, Chen W, Xu J, Chen S, Wang H, Wei J, Li H, Shu M, Lu X, Zhang C, He Y
Frontiers in medicine 2022;9:829033
Frontiers in medicine 2022;9:829033
An Integrated Proteomics and Metabolomics Strategy for the Mechanism of Calcium Oxalate Crystal-Induced Kidney Injury.
Gao S, Chao Y, Li N, Li H, Zhao H, Liu X, Chen W, Dong X
Frontiers in medicine 2022;9:805356
Frontiers in medicine 2022;9:805356
DSC2 Suppresses the Metastasis of Gastric Cancer through Inhibiting the BRD4/Snail Signaling Pathway and the Transcriptional Activity of β-Catenin.
Sun C, Wang L, Du DD, Ji JB, Yang XX, Yu BF, Shang PF, Guo XL
Oxidative medicine and cellular longevity 2022;2022:4813571
Oxidative medicine and cellular longevity 2022;2022:4813571
Antitumor Effect of Si-Jun-Zi Decoction on SGC7901 Gastric Cancer Cells by CMTM2 Activation.
Li X, Chen W, Miao L, Sun H, Gao X, Guo S, Zhang Y, Yang Y, Guo J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4675815
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4675815
Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis.
Xu J, Li Y, Li Z, Shao W, Song J, Wei J
Journal of oncology 2022;2022:3966386
Journal of oncology 2022;2022:3966386
GALNT1 Enhances Malignant Phenotype of Gastric Cancer via Modulating CD44 Glycosylation to Activate the Wnt/β-catenin Signaling Pathway.
Zhang J, Wang H, Wu J, Yuan C, Chen S, Liu S, Huo M, Zhang C, He Y
International journal of biological sciences 2022;18(16):6068-6083
International journal of biological sciences 2022;18(16):6068-6083
Self-Assembly Catalase Nanocomplex Conveyed by Bacterial Vesicles for Oxygenated Photodynamic Therapy and Tumor Immunotherapy.
Zhang J, Li Z, Liu L, Li L, Zhang L, Wang Y, Zhao J
International journal of nanomedicine 2022;17:1971-1985
International journal of nanomedicine 2022;17:1971-1985
Elevated Protein Kinase A Activity in Stomach Mesenchyme Disrupts Mesenchymal-epithelial Crosstalk and Induces Preneoplasia.
Puri P, Grimmett G, Faraj R, Gibson L, Gilbreath E, Yoder BK
Cellular and molecular gastroenterology and hepatology 2022;14(3):643-668.e1
Cellular and molecular gastroenterology and hepatology 2022;14(3):643-668.e1
The Dibenzyl Isoquinoline Alkaloid Berbamine Ameliorates Osteoporosis by Inhibiting Bone Resorption.
Zhang C, Zhong Z, Sang W, Ghorbani F, Ghalandari B, Mohamadali M, Irani S, Qian Z, Yi C, Yu B
Frontiers in endocrinology 2022;13:885507
Frontiers in endocrinology 2022;13:885507
IL25 Enhanced Colitis-Associated Tumorigenesis in Mice by Upregulating Transcription Factor GLI1.
Liu J, Qian B, Zhou L, Shen G, Tan Y, Liu S, Zhao Z, Shi J, Qi W, Zhou T, Yang X, Gao G, Yang Z
Frontiers in immunology 2022;13:837262
Frontiers in immunology 2022;13:837262
The N(6)-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.
Li B, Zhao R, Qiu W, Pan Z, Zhao S, Qi Y, Qiu J, Zhang S, Guo Q, Fan Y, Xu H, Li M, Li G, Xue H
Theranostics 2022;12(14):6363-6379
Theranostics 2022;12(14):6363-6379
Polyphosphate-crosslinked collagen scaffolds for hemostasis and alveolar bone regeneration after tooth extraction.
Gu JT, Jiao K, Li J, Yan JF, Wang KY, Wang F, Liu Y, Tay FR, Chen JH, Niu LN
Bioactive materials 2022 Sep;15:68-81
Bioactive materials 2022 Sep;15:68-81
ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2.
Chen Y, Wang MH, Wu JY, Zhu JY, Xie CF, Li XT, Wu JS, Geng SS, Li YD, Han HY, Zhong CY
The Journal of nutritional biochemistry 2022 Sep;107:109067
The Journal of nutritional biochemistry 2022 Sep;107:109067
GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma.
Chen W, Wang H, Lu Y, Huang Y, Xuan Y, Li X, Guo T, Wang C, Lai D, Wu S, Zhao W, Mai H, Li H, Wang B, Ma X, Zhang X
Laboratory investigation; a journal of technical methods and pathology 2022 Sep;102(9):1011-1022
Laboratory investigation; a journal of technical methods and pathology 2022 Sep;102(9):1011-1022
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
Dang Y, He Q, Yang S, Sun H, Liu Y, Li W, Tang Y, Zheng Y, Wu T
Pharmaceuticals (Basel, Switzerland) 2022 Sep 22;15(10)
Pharmaceuticals (Basel, Switzerland) 2022 Sep 22;15(10)
CAFs-secreted exosomal cricN4BP2L2 promoted colorectal cancer stemness and chemoresistance by interacting with EIF4A3.
Qu Z, Yang KD, Luo BH, Zhang F
Experimental cell research 2022 Sep 15;418(2):113266
Experimental cell research 2022 Sep 15;418(2):113266
Dental pulp stem cells-based therapy for the oviduct injury via immunomodulation and angiogenesis in vivo.
Luo L, Xing Z, Liao X, Li Y, Luo Y, Ai Y, He Y, Ye Q
Cell proliferation 2022 Oct;55(10):e13293
Cell proliferation 2022 Oct;55(10):e13293
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
Zhao X, Shu D, Sun W, Si S, Ran W, Guo B, Cui L
Cancer communications (London, England) 2022 Oct;42(10):987-1007
Cancer communications (London, England) 2022 Oct;42(10):987-1007
Bortezomib prodrug catalytic nanoreactor for chemo/chemodynamic therapy and macrophage re-education.
Huang Y, Guan Z, Ren L, Luo Y, Chen M, Sun Y, He Y, Zeng Z, Dai X, Jiang J, Huang Z, Zhao C
Journal of controlled release : official journal of the Controlled Release Society 2022 Oct;350:332-349
Journal of controlled release : official journal of the Controlled Release Society 2022 Oct;350:332-349
Cellular Hypoxia Mitigation by Dandelion-like Nanoparticles for Synergistic Photodynamic Therapy of Oral Squamous Cell Carcinoma.
Tao Y, Liu Y, Dong Z, Chen X, Wang Y, Li T, Li J, Zang S, He X, Chen D, Zhao Z, Li M
ACS applied materials & interfaces 2022 Oct 5;14(39):44039-44053
ACS applied materials & interfaces 2022 Oct 5;14(39):44039-44053
Babao Dan Alleviates 5-Fluorouracil-Induced Intestinal Damage via Wnt/β-Catenin Pathway.
Gui MX, Huang B, Peng J, Chen X, Muthu R, Gao Y, Wang RG, Lin JM
Chinese journal of integrative medicine 2022 Nov;28(11):1000-1006
Chinese journal of integrative medicine 2022 Nov;28(11):1000-1006
CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway.
Qin C, Li T, Wang Y, Zhao B, Li Z, Li T, Yang X, Zhao Y, Wang W
Cancer cell international 2022 Nov 7;22(1):340
Cancer cell international 2022 Nov 7;22(1):340
Regulation of ZO-1 on β-catenin mediates sulforaphane suppressed colorectal cancer stem cell properties in colorectal cancer.
Chen Y, Tang L, Ye X, Chen Y, Shan E, Han H, Zhong C
Food & function 2022 Nov 28;13(23):12363-12370
Food & function 2022 Nov 28;13(23):12363-12370
CRISPR-mediated MECOM depletion retards tumor growth by reducing cancer stem cell properties in lung squamous cell carcinoma.
Ma Y, Kang B, Li S, Xie G, Bi J, Li F, An G, Liu B, Li J, Shen Y, Xu X, Yang H, Yang Y, Gu Y, Wu N
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Nov 2;30(11):3341-3357
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Nov 2;30(11):3341-3357
Treating intrauterine adhesion using conditionally reprogrammed physiological endometrial epithelial cells.
Xia S, Wu M, Zhou X, Zhang X, Ye L, Zhang K, Kang Y, Liu J, Zhang Y, Wu W, Dong D, Chen H, Li H
Stem cell research & therapy 2022 May 3;13(1):178
Stem cell research & therapy 2022 May 3;13(1):178
Upregulation of Runt related transcription factor 1 (RUNX1) contributes to tendon-bone healing after anterior cruciate ligament reconstruction using bone mesenchymal stem cells.
Kang K, Geng Q, Cui L, Wu L, Zhang L, Li T, Zhang Q, Gao S
Journal of orthopaedic surgery and research 2022 May 13;17(1):266
Journal of orthopaedic surgery and research 2022 May 13;17(1):266
FAM64A promotes HNSCC tumorigenesis by mediating transcriptional autoregulation of FOXM1.
Zhao X, Chen H, Qiu Y, Cui L
International journal of oral science 2022 May 10;14(1):25
International journal of oral science 2022 May 10;14(1):25
SPI1-induced downregulation of FTO promotes GBM progression by regulating pri-miR-10a processing in an m6A-dependent manner.
Zhang S, Zhao S, Qi Y, Li B, Wang H, Pan Z, Xue H, Jin C, Qiu W, Chen Z, Guo Q, Fan Y, Xu J, Gao Z, Wang S, Guo X, Deng L, Ni S, Xue F, Wang J, Zhao R, Li G
Molecular therapy. Nucleic acids 2022 Mar 8;27:699-717
Molecular therapy. Nucleic acids 2022 Mar 8;27:699-717
Claudin1 decrease induced by 1,25-dihydroxy-vitamin D3 potentiates gefitinib resistance therapy through inhibiting AKT activation-mediated cancer stem-like properties in NSCLC cells.
Jia Z, Wang K, Duan Y, Hu K, Zhang Y, Wang M, Xiao K, Liu S, Pan Z, Ding X
Cell death discovery 2022 Mar 18;8(1):122
Cell death discovery 2022 Mar 18;8(1):122
ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis.
Zhang T, Yin C, Fedorov A, Qiao L, Bao H, Beknazarov N, Wang S, Gautam A, Williams RM, Crawford JC, Peri S, Studitsky V, Beg AA, Thomas PG, Walkley C, Xu Y, Poptsova M, Herbert A, Balachandran S
Nature 2022 Jun;606(7914):594-602
Nature 2022 Jun;606(7914):594-602
TDO2 modulates liver cancer cell migration and invasion via the Wnt5a pathway.
Liu H, Xiang Y, Zong QB, Dai ZT, Wu H, Zhang HM, Huang Y, Shen C, Wang J, Lu ZX, Ponnambalam S, Chen K, Wu Y, Zhang TC, Liao XH
International journal of oncology 2022 Jun;60(6)
International journal of oncology 2022 Jun;60(6)
Photosynthetic microorganisms coupled photodynamic therapy for enhanced antitumor immune effect.
Wang H, Liu H, Guo Y, Zai W, Li X, Xiong W, Zhao X, Yao Y, Hu Y, Zou Z, Wu J
Bioactive materials 2022 Jun;12:97-106
Bioactive materials 2022 Jun;12:97-106
SARS-CoV-2 productively infects human brain microvascular endothelial cells.
Yang RC, Huang K, Zhang HP, Li L, Zhang YF, Tan C, Chen HC, Jin ML, Wang XR
Journal of neuroinflammation 2022 Jun 15;19(1):149
Journal of neuroinflammation 2022 Jun 15;19(1):149
Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis.
Chen Y, Zhao H, Liang W, Jiang E, Zhou X, Shao Z, Liu K, Shang Z
Oncogene 2022 Jan;41(5):634-646
Oncogene 2022 Jan;41(5):634-646
Establishment of the SIS scaffold-based 3D model of human peritoneum for studying the dissemination of ovarian cancer.
Herbert SL, Fick A, Heydarian M, Metzger M, Wöckel A, Rudel T, Kozjak-Pavlovic V, Wulff C
Journal of tissue engineering 2022 Jan-Dec;13:20417314221088514
Journal of tissue engineering 2022 Jan-Dec;13:20417314221088514
Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.
Ding R, Li G, Yao Y, Zhang L, Zhang X, Li J, Shen T, Gao Y, Wu T, Kong S, Huang M, Li Y
Journal of physiology and biochemistry 2022 Feb;78(1):99-108
Journal of physiology and biochemistry 2022 Feb;78(1):99-108
Capsaicin inhibits the stemness of anaplastic thyroid carcinoma cells by triggering autophagy-lysosome mediated OCT4A degradation.
Wu L, Xu S, Cheng X, Zhang L, Wang Y, Wu J, Bao J, Yu H, Lu R
Phytotherapy research : PTR 2022 Feb;36(2):938-950
Phytotherapy research : PTR 2022 Feb;36(2):938-950
Epidermal growth factor/epidermal growth factor receptor signaling blockage inhibits tumor cell-derived exosome uptake by oral squamous cell carcinoma through macropinocytosis.
Sasabe E, Tomomura A, Liu H, Sento S, Kitamura N, Yamamoto T
Cancer science 2022 Feb;113(2):609-621
Cancer science 2022 Feb;113(2):609-621
Proteome analysis of NRF2 inhibition in melanoma reveals CD44 up-regulation and increased apoptosis resistance upon vemurafenib treatment.
Weitzenböck HP, Gschwendtner A, Wiesner C, Depke M, Schmidt F, Trautinger F, Hengstschläger M, Hundsberger H, Mikula M
Cancer medicine 2022 Feb;11(4):956-967
Cancer medicine 2022 Feb;11(4):956-967
Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer.
Wei J, Zheng X, Li W, Li X, Fu Z
Cancer cell international 2022 Feb 11;22(1):75
Cancer cell international 2022 Feb 11;22(1):75
A novel type of mesenchymal stem cells derived from bovine metanephric mesenchyme.
Wang Y, Wu Y, Liu Y, Zhang Y, Yang X, Gao Y, Guan W
Tissue & cell 2022 Dec;79:101970
Tissue & cell 2022 Dec;79:101970
CCK regulates osteogenic differentiation through TNFα/NF-κB in peri-implantitis.
Chou L, Chang Y, Lan K, Liu M, Lu Y, Li X, Li P, Xu Y
The Journal of international medical research 2022 Dec;50(12):3000605221141312
The Journal of international medical research 2022 Dec;50(12):3000605221141312
Endothelial cell-derived S1P promotes migration and stemness by binding with GPR63 in colorectal cancer.
Zeng S, Liang Y, Hu H, Wang F, Liang L
Pathology, research and practice 2022 Dec;240:154197
Pathology, research and practice 2022 Dec;240:154197
Exosomes derived from bone marrow mesenchymal stem cells inhibit neuroinflammation after traumatic brain injury.
Wen L, Wang YD, Shen DF, Zheng PD, Tu MD, You WD, Zhu YR, Wang H, Feng JF, Yang XF
Neural regeneration research 2022 Dec;17(12):2717-2724
Neural regeneration research 2022 Dec;17(12):2717-2724
Chromium (VI)-induced ALDH1A1/EGF axis promotes lung cancer progression.
Ge X, Li M, Song GX, Zhang Z, Yin J, Ge Z, Shi Z, Liu LZ, Jiang BH, Qian X, Shen H
Clinical and translational medicine 2022 Dec;12(12):e1136
Clinical and translational medicine 2022 Dec;12(12):e1136
CD44 promotes angiogenesis in myocardial infarction through regulating plasma exosome uptake and further enhancing FGFR2 signaling transduction.
Zhang Q, Chen L, Huang L, Cheng H, Wang L, Xu L, Hu D, He C, Fu C, Wei Q
Molecular medicine (Cambridge, Mass.) 2022 Dec 3;28(1):145
Molecular medicine (Cambridge, Mass.) 2022 Dec 3;28(1):145
The Ginsenoside Compound K Suppresses Stem-Cell-like Properties and Colorectal Cancer Metastasis by Targeting Hypoxia-Driven Nur77-Akt Feed-Forward Signaling.
Zhang M, Shi Z, Zhang S, Li X, To SKY, Peng Y, Liu J, Chen S, Hu H, Wong AST, Zeng JZ
Cancers 2022 Dec 20;15(1)
Cancers 2022 Dec 20;15(1)
EBV promotes vascular mimicry of dormant cancer cells by potentiating stemness and EMT.
Cheng T, Zhang S, Xia T, Zhang Y, Ji Y, Pan S, Xie H, Ren Q, You Y, You B
Experimental cell research 2022 Dec 15;421(2):113403
Experimental cell research 2022 Dec 15;421(2):113403
Multifunctional nanoparticles of sinomenine hydrochloride for treat-to-target therapy of rheumatoid arthritis via modulation of proinflammatory cytokines.
Lin Y, Yi O, Hu M, Hu S, Su Z, Liao J, Wang W, Wang S, Liu L, Liu B, Cai X
Journal of controlled release : official journal of the Controlled Release Society 2022 Aug;348:42-56
Journal of controlled release : official journal of the Controlled Release Society 2022 Aug;348:42-56
Sijunzi Decoction Inhibits Stemness by Suppressing β-Catenin Transcriptional Activity in Gastric Cancer Cells.
Li YJ, Liao LL, Liu P, Tang P, Wang H, Peng QH
Chinese journal of integrative medicine 2022 Aug;28(8):702-710
Chinese journal of integrative medicine 2022 Aug;28(8):702-710
JUN activation modulates chromatin accessibility to drive TNFα-induced mesenchymal transition in glioblastoma.
Lv X, Li Q, Liu H, Gong M, Zhao Y, Hu J, Wu F, Wu X
Journal of cellular and molecular medicine 2022 Aug;26(16):4602-4612
Journal of cellular and molecular medicine 2022 Aug;26(16):4602-4612
CD44-fibrinogen binding promotes bleeding in acute promyelocytic leukemia by in situ fibrin(ogen) deposition.
Wang C, Wang Y, Zuo N, Fang S, Shi J
Blood advances 2022 Aug 9;6(15):4617-4633
Blood advances 2022 Aug 9;6(15):4617-4633
Exosomal DEK removes chemoradiotherapy resistance by triggering quiescence exit of breast cancer stem cells.
Yang YS, Jia XZ, Lu QY, Cai SL, Huang XT, Yang SH, Wood C, Wang YH, Zhou JJ, Chen YD, Yang JS, Yang WJ
Oncogene 2022 Apr;41(18):2624-2637
Oncogene 2022 Apr;41(18):2624-2637
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression.
Yan X, He Y, Yang S, Zeng T, Hua Y, Bao S, Yang F, Duan N, Sun C, Liang Y, Fu Z, Huang X, Li W, Yin Y
Cell death discovery 2022 Apr 12;8(1):196
Cell death discovery 2022 Apr 12;8(1):196
Preclinical Application of Conditional Reprogramming Culture System for Laryngeal and Hypopharyngeal Carcinoma.
Dong Y, Wang J, Ji W, Zheng M, Wang P, Liu L, Li S
Frontiers in cell and developmental biology 2021;9:744969
Frontiers in cell and developmental biology 2021;9:744969
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806
Frontiers in cell and developmental biology 2021;9:679806
ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness.
Cui Y, Yang J, Bai Y, Li Q, Yao Y, Liu C, Wu F, Zhang J, Zhang Y
Frontiers in cell and developmental biology 2021;9:616887
Frontiers in cell and developmental biology 2021;9:616887
Sirt1 Promotes the Restoration of Hepatic Progenitor Cell (HPC)-Mediated Liver Fatty Injury in NAFLD Through Activating the Wnt/β-Catenin Signal Pathway.
Li Q, Gong Y, Wang Y, Liu B, Chu Y, Gui S, Zheng Y, Chen X
Frontiers in nutrition 2021;8:791861
Frontiers in nutrition 2021;8:791861
MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.
Yang W, Tu H, Tang K, Huang H, Ou S, Wu J
Frontiers in cardiovascular medicine 2021;8:709079
Frontiers in cardiovascular medicine 2021;8:709079
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, Qian W, Wang D, Yu D, Zhong C
Nutrition and cancer 2021;73(7):1157-1167
Nutrition and cancer 2021;73(7):1157-1167
Long noncoding RNA SH3PXD2A-AS1 promotes colorectal cancer progression by regulating p53-mediated gene transcription.
Hou P, Lin T, Meng S, Shi M, Chen F, Jiang T, Li Z, Li M, Chu S, Zheng J, Bai J
International journal of biological sciences 2021;17(8):1979-1994
International journal of biological sciences 2021;17(8):1979-1994
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Cui X, Qin T, Zhao Z, Yang G, Sanches JGP, Zhang Q, Fan S, Cao L, Hu X
Journal of Cancer 2021;12(15):4686-4697
Journal of Cancer 2021;12(15):4686-4697
Cronobacter sakazakii ATCC 29544 Translocated Human Brain Microvascular Endothelial Cells via Endocytosis, Apoptosis Induction, and Disruption of Tight Junction.
Jin T, Guan N, Du Y, Zhang X, Li J, Xia X
Frontiers in microbiology 2021;12:675020
Frontiers in microbiology 2021;12:675020
Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer.
Chen J, Wu Y, Luo X, Jin D, Zhou W, Ju Z, Wang D, Meng Q, Wang H, Fu X, Xu J, Song Z
Theranostics 2021;11(15):7507-7526
Theranostics 2021;11(15):7507-7526
The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resistant Prostate Cancer.
Lin Q, Cao J, Du X, Yang K, Shen Y, Wang W, Klocker H, Shi J, Zhang J
Frontiers in oncology 2021;11:787953
Frontiers in oncology 2021;11:787953
YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma.
Xie Q, Zhao S, Liu W, Cui Y, Li F, Li Z, Guo T, Yu W, Guo W, Deng W, Gu C
Frontiers in oncology 2021;11:702491
Frontiers in oncology 2021;11:702491
The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway.
Sanches JGP, Song B, Zhang Q, Cui X, Yabasin IB, Ntim M, Li X, He J, Zhang Y, Mao J, Lu Y, Li L
Frontiers in oncology 2021;11:637298
Frontiers in oncology 2021;11:637298
Discovering and Characterizing of Survivin Dominant Negative Mutants With Stronger Pro-apoptotic Activity on Cancer Cells and CSCs.
Guo W, Ma X, Fu Y, Liu C, Liu Q, Hu F, Miao H, Zhang T, Liu Y, Han MH, You F, Yang Y, Zheng W
Frontiers in oncology 2021;11:635233
Frontiers in oncology 2021;11:635233
MiR-552-3p promotes malignant progression of gallbladder carcinoma by reactivating the Akt/β-catenin signaling pathway due to inhibition of the tumor suppressor gene RGMA.
Song F, Yang Z, Li L, Wei Y, Tang X, Liu S, Yu M, Chen J, Wang S, Fu J, Zhang K, Yang P, Yang X, Chen Z, Zhang B, Wang H
Annals of translational medicine 2021 Sep;9(17):1374
Annals of translational medicine 2021 Sep;9(17):1374
Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma.
Xie J, Wang Z, Fan W, Liu Y, Liu F, Wan X, Liu M, Wang X, Zeng D, Wang Y, He B, Yan M, Zhang Z, Zhang M, Hou Z, Wang C, Kang Z, Fang W, Zhang L, Lam EW, Guo X, Yan J, Zeng Y, Chen M, Liu Q
Signal transduction and targeted therapy 2021 Sep 4;6(1):333
Signal transduction and targeted therapy 2021 Sep 4;6(1):333
Circular RNA cia-MAF drives self-renewal and metastasis of liver tumor-initiating cells via transcription factor MAFF.
Chen Z, Lu T, Huang L, Wang Z, Yan Z, Guan Y, Hu W, Fan Z, Zhu P
The Journal of clinical investigation 2021 Oct 1;131(19)
The Journal of clinical investigation 2021 Oct 1;131(19)
Single-Cell Analyses Reveal Mechanisms of Cancer Stem Cell Maintenance and Epithelial-Mesenchymal Transition in Recurrent Bladder Cancer.
Wang H, Mei Y, Luo C, Huang Q, Wang Z, Lu GM, Qin L, Sun Z, Huang CW, Yang ZW, Chen J, Yin W, Qian CN, Zeng J, Chen L, Leng Q, Guo Y, Jia G
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Nov 15;27(22):6265-6278
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Nov 15;27(22):6265-6278
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Gao C, Jia W, Xu W, Wu Q, Wu J
Journal of neuroinflammation 2021 May 22;18(1):118
Journal of neuroinflammation 2021 May 22;18(1):118
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
Long Y, Wang Z, Fan J, Yuan L, Tong C, Zhao Y, Liu B
Journal of materials chemistry. B 2021 May 12;9(18):3838-3855
Journal of materials chemistry. B 2021 May 12;9(18):3838-3855
Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation.
Zhu J, Li X, Liang C, Zhou X, Ge M, Chen Y, Jin J, Yin J, Xu H, Xie C, Zhong C
Cell death discovery 2021 May 12;7(1):102
Cell death discovery 2021 May 12;7(1):102
A novel Lnc408 maintains breast cancer stem cell stemness by recruiting SP3 to suppress CBY1 transcription and increasing nuclear β-catenin levels.
Wen S, Qin Y, Wang R, Yang L, Zeng H, Zhu P, Li Q, Qiu Y, Chen S, Liu Y, Hou Y, Tang X, Liu M, Tu G
Cell death & disease 2021 May 1;12(5):437
Cell death & disease 2021 May 1;12(5):437
Diallyl trisulfide inhibited tobacco smoke-mediated bladder EMT and cancer stem cell marker expression via the NF-κB pathway in vivo.
Geng H, Guo W, Feng L, Xie D, Bi L, Wang Y, Zhang T, Liang Z, Yu D
The Journal of international medical research 2021 Mar;49(3):300060521992900
The Journal of international medical research 2021 Mar;49(3):300060521992900
SHARPIN stabilizes β-catenin through a linear ubiquitination-independent manner to support gastric tumorigenesis.
Zhang L, Liu Q, Liu KW, Qin ZY, Zhu GX, Shen LT, Zhang N, Liu BY, Che LR, Li JY, Wang T, Wen LZ, Liu KJ, Guo Y, Yin XR, Wang XW, Zhou ZH, Xiao HL, Cui YH, Bian XW, Lan CH, Chen D, Wang B
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2021 Mar;24(2):402-416
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2021 Mar;24(2):402-416
SOCS6 promotes radiosensitivity and decreases cancer cell stemness in esophageal squamous cell carcinoma by regulating c-Kit ubiquitylation.
Sun X, Sun Y, Li J, Zhao X, Shi X, Gong T, Pan S, Zheng Z, Zhang X
Cancer cell international 2021 Mar 12;21(1):165
Cancer cell international 2021 Mar 12;21(1):165
S100 calcium-binding protein A9 from tumor-associated macrophage enhances cancer stem cell-like properties of hepatocellular carcinoma.
Wei R, Zhu WW, Yu GY, Wang X, Gao C, Zhou X, Lin ZF, Shao WQ, Wang SH, Lu M, Qin LX
International journal of cancer 2021 Mar 1;148(5):1233-1244
International journal of cancer 2021 Mar 1;148(5):1233-1244
Diallyl trisulphide, a H(2) S donor, compromises the stem cell phenotype and restores thyroid-specific gene expression in anaplastic thyroid carcinoma cells by targeting AKT-SOX2 axis.
Zhang L, Xu S, Cheng X, Zheng J, Wang Y, Wu J, Wang X, Wu L, Yu H, Bao J
Phytotherapy research : PTR 2021 Jun;35(6):3428-3443
Phytotherapy research : PTR 2021 Jun;35(6):3428-3443
Expression of CD44 and CD133 stem cell markers in squamous cell carcinoma of esophagus.
Gupta P, Rizvi SZ, Lal N, Gupta V, Srivastav AN, Musa O
Indian journal of pathology & microbiology 2021 Jul-Sep;64(3):472-478
Indian journal of pathology & microbiology 2021 Jul-Sep;64(3):472-478
LncRNA LPAL2/miR-1287-5p/EGFR Axis Modulates TED-Derived Orbital Fibroblast Activation Through Cell Adhesion Factors.
Wang N, Hou SY, Qi X, Deng M, Cao JM, Tong BD, Xiong W
The Journal of clinical endocrinology and metabolism 2021 Jul 13;106(8):e2866-e2886
The Journal of clinical endocrinology and metabolism 2021 Jul 13;106(8):e2866-e2886
A "dual-guide" bioinspired drug delivery strategy of a macrophage-based carrier against postoperative triple-negative breast cancer recurrence.
Qiu Y, Ren K, Zhao W, Yu Q, Guo R, He J, Mei L, Liu Y, Tang J, Xu S, Li J, Wei J, Li M, Zhang Z, He Q
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:191-204
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:191-204
Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.
Wang D, Xie D, Bi L, Wang Y, Zou C, Chen L, Geng H, Qian W, Li Y, Sun H, Wang X, Lu Y, Yu D, Zhong C
Oncology letters 2021 Feb;21(2):146
Oncology letters 2021 Feb;21(2):146
Grade-targeted nanoparticles for improved hypoxic tumor microenvironment and enhanced photodynamic cancer therapy.
Tao YK, Hou XY, Gao H, Zhang X, Zuo FM, Wang Y, Li XX, Jiang G
Nanomedicine (London, England) 2021 Feb;16(3):221-235
Nanomedicine (London, England) 2021 Feb;16(3):221-235
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Zhang M, Wang L, Yue Y, Zhang L, Liu T, Jing M, Liang X, Ma M, Xu S, Wang K, Wang X, Fan J
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
RAB27A-dependent release of exosomes by liver cancer stem cells induces Nanog expression in their differentiated progenies and confers regorafenib resistance.
Huang H, Hou J, Liu K, Liu Q, Shen L, Liu B, Lu Q, Zhang N, Che L, Li J, Jiang S, Wang B, Wen Q, Hu L, Gao J
Journal of gastroenterology and hepatology 2021 Dec;36(12):3429-3437
Journal of gastroenterology and hepatology 2021 Dec;36(12):3429-3437
miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling.
Peng J, Shi S, Yu J, Liu J, Wei H, Song H, Wang S, Li Z, He S, Li L, Zhang H, Yan Z, Zhao R, Liu Y, Liu Y, Li J, Zhang R, Wang W
Cancer cell international 2021 Dec 22;21(1):702
Cancer cell international 2021 Dec 22;21(1):702
EBV latent membrane proteins promote hybrid epithelial-mesenchymal and extreme mesenchymal states of nasopharyngeal carcinoma cells for tumorigenicity.
Zhu N, Xu X, Wang Y, Zeng MS, Yuan Y
PLoS pathogens 2021 Aug;17(8):e1009873
PLoS pathogens 2021 Aug;17(8):e1009873
FOXD1 promotes EMT and cell stemness of oral squamous cell carcinoma by transcriptional activation of SNAI2.
Chen Y, Liang W, Liu K, Shang Z
Cell & bioscience 2021 Aug 4;11(1):154
Cell & bioscience 2021 Aug 4;11(1):154
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Liao Y, Hua Y, Li Y, Zhang C, Yu W, Guo P, Zou K, Li W, Sun Y, Wang R, Zuo Y, Sui S, Tian C, Hao J, Chen M, Hu S, Chen M, Long Q, Wang X, Zou L, Xie F, Guo W, Deng W
Cell death and differentiation 2021 Apr;28(4):1347-1363
Cell death and differentiation 2021 Apr;28(4):1347-1363
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
Diao C, Guo P, Yang W, Sun Y, Liao Y, Yan Y, Zhao A, Cai X, Hao J, Hu S, Yu W, Chen M, Wang R, Li W, Zuo Y, Pan J, Hua C, Lu X, Fan W, Zheng Z, Deng W, Luo G, Guo W
Molecular oncology 2021 Apr;15(4):1180-1202
Molecular oncology 2021 Apr;15(4):1180-1202
CD44-Targeting Oxygen Self-Sufficient Nanoparticles for Enhanced Photodynamic Therapy Against Malignant Melanoma.
Hou X, Tao Y, Li X, Pang Y, Yang C, Jiang G, Liu Y
International journal of nanomedicine 2020;15:10401-10416
International journal of nanomedicine 2020;15:10401-10416
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
ARPP-19 Mediates Herceptin Resistance via Regulation of CD44 in Gastric Cancer.
Gao X, Lu C, Chen C, Sun K, Liang Q, Shuai J, Wang X, Xu Y
OncoTargets and therapy 2020;13:6629-6643
OncoTargets and therapy 2020;13:6629-6643
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Su P, Ahmad B, Zou K, Zou L
OncoTargets and therapy 2020;13:5207-5222
OncoTargets and therapy 2020;13:5207-5222
Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells.
Wu DM, Liu T, Deng SH, Han R, Zhang T, Li J, Xu Y
OncoTargets and therapy 2020;13:3751-3763
OncoTargets and therapy 2020;13:3751-3763
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
Yang B, Bai H, Sa Y, Zhu P, Liu P
Journal of Cancer 2020;11(8):2303-2317
Journal of Cancer 2020;11(8):2303-2317
A sericin/ graphene oxide composite scaffold as a biomimetic extracellular matrix for structural and functional repair of calvarial bone.
Qi C, Deng Y, Xu L, Yang C, Zhu Y, Wang G, Wang Z, Wang L
Theranostics 2020;10(2):741-756
Theranostics 2020;10(2):741-756
Enrichment of CD44 in Exosomes From Breast Cancer Cells Treated With Doxorubicin Promotes Chemoresistance.
Wang X, Cheng K, Zhang G, Jia Z, Yu Y, Guo J, Hua Y, Guo F, Li X, Zou W, Sun H, Dong J, Yang Z
Frontiers in oncology 2020;10:960
Frontiers in oncology 2020;10:960
CCL21/CCR7 interaction promotes EMT and enhances the stemness of OSCC via a JAK2/STAT3 signaling pathway.
Chen Y, Shao Z, Jiang E, Zhou X, Wang L, Wang H, Luo X, Chen Q, Liu K, Shang Z
Journal of cellular physiology 2020 Sep;235(9):5995-6009
Journal of cellular physiology 2020 Sep;235(9):5995-6009
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Guo X, Dai X, Liu J, Cheng A, Qin C, Wang Z
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
MicroRNA-148a-3p inhibits cancer progression and is a novel screening biomarker for gastric cancer.
Bao C, Guo L
Journal of clinical laboratory analysis 2020 Oct;34(10):e23454
Journal of clinical laboratory analysis 2020 Oct;34(10):e23454
5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation.
Cho YH, Ro EJ, Yoon JS, Mizutani T, Kang DW, Park JC, Il Kim T, Clevers H, Choi KY
Nature communications 2020 Oct 21;11(1):5321
Nature communications 2020 Oct 21;11(1):5321
TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition.
Chen Y, Wang MH, Zhu JY, Xie CF, Li XT, Wu JS, Geng SS, Han HY, Zhong CY
Oncogenesis 2020 Oct 10;9(10):89
Oncogenesis 2020 Oct 10;9(10):89
Nanog mediates tobacco smoke-induced enhancement of renal cancer stem cell properties.
Zhang T, Sun H, Liu R, Cao W, Zhang T, Li E, Sun X, Wu W, Yu D, Zhong C
Environmental toxicology 2020 Nov;35(11):1274-1283
Environmental toxicology 2020 Nov;35(11):1274-1283
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
Xiang L, Huang X, Wang S, Ou H, Chen Z, Hu Z, Huang Y, Li X, Yuan Y, Yang D
Cancer science 2020 Nov;111(11):4102-4117
Cancer science 2020 Nov;111(11):4102-4117
Destabilization of β-catenin and RAS by targeting the Wnt/β-catenin pathway as a potential treatment for triple-negative breast cancer.
Ryu WJ, Lee JD, Park JC, Cha PH, Cho YH, Kim JY, Sohn JH, Paik S, Choi KY
Experimental & molecular medicine 2020 May;52(5):832-842
Experimental & molecular medicine 2020 May;52(5):832-842
The miRNA-149-5p/MyD88 axis is responsible for ursolic acid-mediated attenuation of the stemness and chemoresistance of non-small cell lung cancer cells.
Chen Q, Luo J, Wu C, Lu H, Cai S, Bao C, Liu D, Kong J
Environmental toxicology 2020 May;35(5):561-569
Environmental toxicology 2020 May;35(5):561-569
KIAA1429 promotes osteosarcoma progression by promoting stem cell properties and is regulated by miR-143-3p.
Han Q, Yang J, Yang H, Li C, Li J, Cao Y
Cell cycle (Georgetown, Tex.) 2020 May;19(10):1172-1185
Cell cycle (Georgetown, Tex.) 2020 May;19(10):1172-1185
A mutant KRAS-induced factor REG4 promotes cancer stem cell properties via Wnt/β-catenin signaling.
Hwang JH, Yoon J, Cho YH, Cha PH, Park JC, Choi KY
International journal of cancer 2020 May 15;146(10):2877-2890
International journal of cancer 2020 May 15;146(10):2877-2890
Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties.
Takasugi M, Firsanov D, Tombline G, Ning H, Ablaeva J, Seluanov A, Gorbunova V
Nature communications 2020 May 12;11(1):2376
Nature communications 2020 May 12;11(1):2376
Inhibition of miR-9 decreases osteosarcoma cell proliferation.
Gang W, Tanjun W, Yong H, Jiajun Q, Yi Z, Hao H
Bosnian journal of basic medical sciences 2020 May 1;20(2):218-225
Bosnian journal of basic medical sciences 2020 May 1;20(2):218-225
MiR-7 reduces the BCSC subset by inhibiting XIST to modulate the miR-92b/Slug/ESA axis and inhibit tumor growth.
Li M, Pan M, You C, Zhao F, Wu D, Guo M, Xu H, Shi F, Zheng D, Dou J
Breast cancer research : BCR 2020 Mar 6;22(1):26
Breast cancer research : BCR 2020 Mar 6;22(1):26
Hypoxia-induced lncRNA PDIA3P1 promotes mesenchymal transition via sponging of miR-124-3p in glioma.
Wang S, Qi Y, Gao X, Qiu W, Liu Q, Guo X, Qian M, Chen Z, Zhang Z, Wang H, Xu J, Xue H, Guo X, Zhang P, Zhao R, Li G
Cell death & disease 2020 Mar 3;11(3):168
Cell death & disease 2020 Mar 3;11(3):168
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, Hu S, Guo P, Chen M, Sui S, Xiong Y, Li F, Lu J, Guo W, Luo G, Deng W
Cell death & disease 2020 Jul 6;11(7):506
Cell death & disease 2020 Jul 6;11(7):506
Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
Wang B, Ye Q, Zou C
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507
Stem-like tumor cells involved in heterogeneous vasculogenesis in breast cancer.
Mao Y, Zhu L, Huang Z, Luo C, Zhou T, Li L, Wang G, Yang Z, Qi W, Yang X, Gao G
Endocrine-related cancer 2020 Jan;27(1):23-39
Endocrine-related cancer 2020 Jan;27(1):23-39
UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop.
Liu X, Ma F, Liu C, Zhu K, Li W, Xu Y, Li G, Niu Z, Liu J, Chen D, Li Z, Fu Y, Qian C
Cell death & disease 2020 Jan 6;11(1):10
Cell death & disease 2020 Jan 6;11(1):10
P38 MAPK signaling pathway mediates COM crystal-induced crystal adhesion change in rat renal tubular epithelial cells.
Qi S, Wang Q, Xie B, Chen Y, Zhang Z, Xu Y
Urolithiasis 2020 Feb;48(1):9-18
Urolithiasis 2020 Feb;48(1):9-18
Inhibition of breast cancer growth via miR-7 suppressing ALDH1A3 activity concomitant with decreasing breast cancer stem cell subpopulation.
Pan M, Li M, You C, Zhao F, Guo M, Xu H, Li L, Wang L, Dou J
Journal of cellular physiology 2020 Feb;235(2):1405-1416
Journal of cellular physiology 2020 Feb;235(2):1405-1416
RNA Binding Protein RNPC1 Suppresses the Stemness of Human Endometrial Cancer Cells via Stabilizing MST1/2 mRNA.
Wu X, Wang Y, Zhong W, Cheng H, Tian Z
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 23;26:e921389
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 23;26:e921389
An all-silk-derived functional nanosphere matrix for sequential biomolecule delivery and in situ osteochondral regeneration.
Zhang W, Ling C, Zhang A, Liu H, Jiang Y, Li X, Sheng R, Yao Q, Chen J
Bioactive materials 2020 Dec;5(4):832-843
Bioactive materials 2020 Dec;5(4):832-843
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
Zou K, Li Z, Zhang Y, Mu L, Chen M, Wang R, Deng W, Zou L, Liu J
Aging 2020 Dec 9;13(2):2575-2592
Aging 2020 Dec 9;13(2):2575-2592
Diospyros kaki leaves inhibit HGF/Met signaling-mediated EMT and stemness features in hepatocellular carcinoma.
Ko H, Huh G, Jung SH, Kwon H, Jeon Y, Park YN, Kim YJ
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Aug;142:111475
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Aug;142:111475
WISP-2, an upregulated gene in hip cartilage from the DDH model rats, induces chondrocyte apoptosis through PPARγ in vitro.
Ji X, Liu T, Zhao S, Li J, Li L, Wang E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):4904-4917
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):4904-4917
The cancer cell glycocalyx proteoglycan Glypican-1 mediates interstitial flow mechanotransduction to enhance cell migration and metastasis.
Moran H, Cancel LM, Mayer MA, Qazi H, Munn LL, Tarbell JM
Biorheology 2019;56(2-3):151-161
Biorheology 2019;56(2-3):151-161
Human colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF.
Zhang R, Qi F, Shao S, Li G, Feng Y
Cancer cell international 2019;19:192
Cancer cell international 2019;19:192
CD44 3'-Untranslated Region Functions as a Competing Endogenous RNA to Enhance NK Sensitivity of Liver Cancer Stem Cell by Regulating ULBP2 Expression.
Weng J, Han X, Liu K, Yang J, Wei S, Zhang Y, Zeng F, Li Y, Shen L, Gao Y
International journal of biological sciences 2019;15(8):1664-1675
International journal of biological sciences 2019;15(8):1664-1675
Nuclear CD44 Mediated by Importin β Participated in Naïve Genes Transcriptional Regulation in C3A-iCSCs.
Su M, Wang P, Wang X, Zhang M, Wei S, Liu K, Han S, Han X, Deng Y, Shen L
International journal of biological sciences 2019;15(6):1252-1260
International journal of biological sciences 2019;15(6):1252-1260
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling.
Pan TJ, Li LX, Zhang JW, Yang ZS, Shi DM, Yang YK, Wu WZ
Journal of Cancer 2019;10(20):4777-4792
Journal of Cancer 2019;10(20):4777-4792
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, Zhong C
Oncology letters 2019 Sep;18(3):3081-3091
Oncology letters 2019 Sep;18(3):3081-3091
MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer.
Wei C, Zhang R, Cai Q, Gao X, Tong F, Dong J, Hu Y, Wu G, Dong X
Aging 2019 Sep 8;11(17):6734-6761
Aging 2019 Sep 8;11(17):6734-6761
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Wang SS, Zheng M, Pang X, Zhang M, Yu XH, Wu JB, Gao XL, Wu JS, Yang X, Tang YJ, Tang YL, Liang XH
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
FNDC3B circular RNA promotes the migration and invasion of gastric cancer cells via the regulation of E-cadherin and CD44 expression.
Hong Y, Qin H, Li Y, Zhang Y, Zhuang X, Liu L, Lu K, Li L, Deng X, Liu F, Shi S, Liu G
Journal of cellular physiology 2019 Nov;234(11):19895-19910
Journal of cellular physiology 2019 Nov;234(11):19895-19910
Targeting Frizzled-7 Decreases Stemness and Chemotherapeutic Resistance in Gastric Cancer Cells by Suppressing Myc Expression.
Cheng Y, Li L, Pan S, Jiang H, Jin H
Medical science monitor : international medical journal of experimental and clinical research 2019 Nov 16;25:8637-8644
Medical science monitor : international medical journal of experimental and clinical research 2019 Nov 16;25:8637-8644
In-vivo anti-tumor activity of a novel poloxamer-based thermosensitive in situ gel for sustained delivery of norcantharidin.
Xie MH, Ge M, Peng JB, Jiang XR, Wang DS, Ji LQ, Ying Y, Wang Z
Pharmaceutical development and technology 2019 Jun;24(5):623-629
Pharmaceutical development and technology 2019 Jun;24(5):623-629
PES1 is regulated by CD44 in liver cancer stem cells via miR-105-5p.
Wei S, Liu K, He Q, Gao Y, Shen L
FEBS letters 2019 Jul;593(14):1777-1786
FEBS letters 2019 Jul;593(14):1777-1786
WDR76 degrades RAS and suppresses cancer stem cell activation in colorectal cancer.
Ro EJ, Cho YH, Jeong WJ, Park JC, Min DS, Choi KY
Cell communication and signaling : CCS 2019 Jul 30;17(1):88
Cell communication and signaling : CCS 2019 Jul 30;17(1):88
Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.
Yuan W, Ji J, Shu Y, Chen J, Liu S, Wu L, Zhou Z, Liu Z, Tang Q, Zhang X, Shu X
Journal of molecular medicine (Berlin, Germany) 2019 Jan;97(1):89-102
Journal of molecular medicine (Berlin, Germany) 2019 Jan;97(1):89-102
BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.
Zhao X, Zheng F, Li Y, Hao J, Tang Z, Tian C, Yang Q, Zhu T, Diao C, Zhang C, Chen M, Hu S, Guo P, Zhang L, Liao Y, Yu W, Chen M, Zou L, Guo W, Deng W
Redox biology 2019 Jan;20:427-441
Redox biology 2019 Jan;20:427-441
Osterix promotes the migration and angiogenesis of breast cancer by upregulation of S100A4 expression.
Qu S, Wu J, Bao Q, Yao B, Duan R, Chen X, Li L, Yuan H, Jin Y, Ma C
Journal of cellular and molecular medicine 2019 Feb;23(2):1116-1127
Journal of cellular and molecular medicine 2019 Feb;23(2):1116-1127
MicroRNA-135a-5p promotes neuronal differentiation of pluripotent embryonal carcinoma cells by repressing Sox6/CD44 pathway.
Li W, Fang J, Shen J, Liu X, Hou J, Zhu Y, Ma X
Biochemical and biophysical research communications 2019 Feb 5;509(2):603-610
Biochemical and biophysical research communications 2019 Feb 5;509(2):603-610
Metabolomic analysis reveals a protective effect of Fu-Fang-Jin-Qian-Chao herbal granules on oxalate-induced kidney injury.
Chen W, Liu WR, Hou JB, Ding JR, Peng ZJ, Gao SY, Dong X, Ma JH, Lin QS, Lu JR, Guo ZY
Bioscience reports 2019 Feb 28;39(2)
Bioscience reports 2019 Feb 28;39(2)
Pseudomonas aeruginosa ExsA Regulates a Metalloprotease, ImpA, That Inhibits Phagocytosis of Macrophages.
Tian Z, Cheng S, Xia B, Jin Y, Bai F, Cheng Z, Jin S, Liu X, Wu W
Infection and immunity 2019 Dec;87(12)
Infection and immunity 2019 Dec;87(12)
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, Meng Y, Chen Y, Wang X, Chen J, Zhang Q, Shao J, Zhong C
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, Wang Y
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
A Therapeutic Strategy for Chemotherapy-Resistant Gastric Cancer via Destabilization of Both β-Catenin and RAS.
Ryu WJ, Lee JE, Cho YH, Lee G, Seo MK, Lee SK, Hwang JH, Min DS, Noh SH, Paik S, Kim S, Cheong JH, Choi KY
Cancers 2019 Apr 8;11(4)
Cancers 2019 Apr 8;11(4)
Long non-coding RNA DILC promotes the progression of gallbladder carcinoma.
Liang C, Yang P, Han T, Wang RY, Xing XL, Si AF, Ma QY, Chen Z, Li HY, Zhang B
Gene 2019 Apr 30;694:102-110
Gene 2019 Apr 30;694:102-110
The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling.
Wu DM, Zhang T, Liu YB, Deng SH, Han R, Liu T, Li J, Xu Y
Cell death & disease 2019 Apr 25;10(5):349
Cell death & disease 2019 Apr 25;10(5):349
Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19.
Ren J, Ding L, Zhang D, Shi G, Xu Q, Shen S, Wang Y, Wang T, Hou Y
Theranostics 2018;8(14):3932-3948
Theranostics 2018;8(14):3932-3948
CD44 is overexpressed and correlated with tumor progression in gallbladder cancer.
He Y, Xue C, Yu Y, Chen J, Chen X, Ren F, Ren Z, Cui G, Sun R
Cancer management and research 2018;10:3857-3865
Cancer management and research 2018;10:3857-3865
Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells.
Su P, Yang Y, Wang G, Chen X, Ju Y
International journal of oncology 2018 Sep;53(3):1343-1353
International journal of oncology 2018 Sep;53(3):1343-1353
Tumor suppressor LKB1 inhibits the progression of gallbladder carcinoma and predicts the prognosis of patients with this malignancy.
Hu MT, Wang JH, Yu Y, Liu C, Li B, Cheng QB, Jiang XQ
International journal of oncology 2018 Sep;53(3):1215-1226
International journal of oncology 2018 Sep;53(3):1215-1226
LGR5, a novel functional glioma stem cell marker, promotes EMT by activating the Wnt/β-catenin pathway and predicts poor survival of glioma patients.
Zhang J, Cai H, Sun L, Zhan P, Chen M, Zhang F, Ran Y, Wan J
Journal of experimental & clinical cancer research : CR 2018 Sep 12;37(1):225
Journal of experimental & clinical cancer research : CR 2018 Sep 12;37(1):225
Isobavachalcone sensitizes cells to E2-induced paclitaxel resistance by down-regulating CD44 expression in ER+ breast cancer cells.
Shi J, Chen Y, Chen W, Tang C, Zhang H, Chen Y, Yang X, Xu Z, Wei J, Chen J
Journal of cellular and molecular medicine 2018 Nov;22(11):5220-5230
Journal of cellular and molecular medicine 2018 Nov;22(11):5220-5230
Proteomic Analysis of Plasma Membrane Proteins of Antler Stem Cells Using Label-Free LC⁻MS/MS.
Wang D, Ba H, Li C, Zhao Q, Li C
International journal of molecular sciences 2018 Nov 5;19(11)
International journal of molecular sciences 2018 Nov 5;19(11)
Studying the mechanism of PLAGL2 overexpression and its carcinogenic characteristics based on 3'-untranslated region in colorectal cancer.
Su C, Li D, Li N, Du Y, Yang C, Bai Y, Lin C, Li X, Zhang Y
International journal of oncology 2018 May;52(5):1479-1490
International journal of oncology 2018 May;52(5):1479-1490
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Li X, Meng Y, Xie C, Zhu J, Wang X, Li Y, Geng S, Wu J, Zhong C, Li M
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Qian W, Kong X, Zhang T, Wang D, Song J, Li Y, Li X, Geng H, Min J, Kong Q, Liu J, Liu Z, Wang D, Zhang Z, Yu D, Zhong C
Oncogenesis 2018 Mar 13;7(3):24
Oncogenesis 2018 Mar 13;7(3):24
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Zhang Q, Li XT, Chen Y, Chen JQ, Zhu JY, Meng Y, Wang XQ, Li Y, Geng SS, Xie CF, Wu JS, Zhong CY, Han HY
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Song L, Chen X, Wang P, Gao S, Qu C, Liu L
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Wang J, Tian L, Khan MN, Zhang L, Chen Q, Zhao Y, Yan Q, Fu L, Liu J
Cancer letters 2018 Feb 28;415:73-85
Cancer letters 2018 Feb 28;415:73-85
Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system.
Saito Y, Nakaoka T, Muramatsu T, Ojima H, Sukeda A, Sugiyama Y, Uchida R, Furukawa R, Kitahara A, Sato T, Kanai Y, Saito H
Scientific reports 2018 Feb 12;8(1):2821
Scientific reports 2018 Feb 12;8(1):2821
Endogenous and exogenous galectin-3 promote the adhesion of tumor cells with low expression of MUC1 to HUVECs through upregulation of N-cadherin and CD44.
Cao Z, Hao Z, Xin M, Yu L, Wang L, Zhang Y, Zhang X, Guo X
Laboratory investigation; a journal of technical methods and pathology 2018 Dec;98(12):1642-1656
Laboratory investigation; a journal of technical methods and pathology 2018 Dec;98(12):1642-1656
miR-1307-3p suppresses the chondrogenic differentiation of human adipose-derived stem cells by targeting BMPR2.
Yang Z, Li R, Ao J, Wa QD, Zhang Y, Chen L, Wen J, Chen B, Pan W, Li B, Tian XB
International journal of molecular medicine 2018 Dec;42(6):3115-3124
International journal of molecular medicine 2018 Dec;42(6):3115-3124
Inhibiting transforming growth factor-β signaling regulates in vitro maintenance and differentiation of bovine bone marrow mesenchymal stem cells.
Zhao XX, An XL, Zhu XC, Jiang Y, Zhai YH, Zhang S, Cai NN, Tang B, Li ZY, Zhang XM
Journal of experimental zoology. Part B, Molecular and developmental evolution 2018 Dec;330(8):406-416
Journal of experimental zoology. Part B, Molecular and developmental evolution 2018 Dec;330(8):406-416
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Chen Y, Li Y, Wang XQ, Meng Y, Zhang Q, Zhu JY, Chen JQ, Cao WS, Wang XQ, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability.
Lu Y, Maruyama J, Kuwata K, Fukuda H, Iwasa H, Arimoto-Matsuzaki K, Sugimura H, Hata Y
Biochemistry and biophysics reports 2018 Dec;16:130-137
Biochemistry and biophysics reports 2018 Dec;16:130-137
High-resolution acoustophoretic 3D cell patterning to construct functional collateral cylindroids for ischemia therapy.
Kang B, Shin J, Park HJ, Rhyou C, Kang D, Lee SJ, Yoon YS, Cho SW, Lee H
Nature communications 2018 Dec 20;9(1):5402
Nature communications 2018 Dec 20;9(1):5402
CD44-targeted hyaluronic acid-curcumin prodrug protects renal tubular epithelial cell survival from oxidative stress damage.
Hu JB, Li SJ, Kang XQ, Qi J, Wu JH, Wang XJ, Xu XL, Ying XY, Jiang SP, You J, Du YZ
Carbohydrate polymers 2018 Aug 1;193:268-280
Carbohydrate polymers 2018 Aug 1;193:268-280
A Ultrasensitive Near-Infrared Fluorescent Probe Reveals Pyroglutamate Aminopeptidase 1 Can Be a New Inflammatory Cytokine.
Gong Q, Zou R, Xing J, Xiang L, Zhang R, Wu A
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2018 Apr;5(4):1700664
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2018 Apr;5(4):1700664
Histochemical evidence of IGF2 mRNA-binding protein 2-mediated regulation of osteoclast function and adhesive ability.
Liu H, Li D, Liu S, Liu Z, Li M
Histochemistry and cell biology 2018 Apr;149(4):343-351
Histochemistry and cell biology 2018 Apr;149(4):343-351
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Yang HF, Yu M, Jin HD, Yao JQ, Lu ZL, Yabasin IB, Yan Q, Wen QP
Frontiers in physiology 2017;8:510
Frontiers in physiology 2017;8:510
miR34a/GOLPH3 Axis abrogates Urothelial Bladder Cancer Chemoresistance via Reduced Cancer Stemness.
Zhang Q, Zhuang J, Deng Y, Yang L, Cao W, Chen W, Lin T, Lv X, Yu H, Xue Y, Guo H
Theranostics 2017;7(19):4777-4790
Theranostics 2017;7(19):4777-4790
β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Yu W, Li L, Zheng F, Yang W, Zhao S, Tian C, Yin W, Chen Y, Guo W, Zou L, Deng W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):467-478
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):467-478
Prohibitin, relocated to the front ends, can control the migration directionality of colorectal cancer cells.
Ma LL, Shen L, Tong GH, Tang N, Luo Y, Guo LL, Hu CT, Huang YX, Huang G, Jing FY, Liu C, Li ZY, Zhou N, Yan QW, Lei Y, Zhu SJ, Cheng ZQ, Cao GW, Deng YJ, Ding YQ
Oncotarget 2017 Sep 29;8(44):76340-76356
Oncotarget 2017 Sep 29;8(44):76340-76356
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, Yu D, Zhong C
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Overexpression of PER3 Inhibits Self-Renewal Capability and Chemoresistance of Colorectal Cancer Stem-Like Cells via Inhibition of Notch and β-Catenin Signaling.
Zhang F, Sun H, Zhang S, Yang X, Zhang G, Su T
Oncology research 2017 May 24;25(5):709-719
Oncology research 2017 May 24;25(5):709-719
Adipocytes enhance expression of osteoclast adhesion-related molecules through the CXCL12/CXCR4 signalling pathway.
Luo T, Liu H, Feng W, Liu D, Du J, Sun J, Wang W, Han X, Guo J, Amizuka N, Li X, Li M
Cell proliferation 2017 Jun;50(3)
Cell proliferation 2017 Jun;50(3)
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Zhu J, Wang S, Chen Y, Li X, Jiang Y, Yang X, Li Y, Wang X, Meng Y, Zhu M, Ma X, Huang C, Wu R, Xie C, Geng S, Wu J, Zhong C, Han H
The Journal of nutritional biochemistry 2017 Jun;44:80-91
The Journal of nutritional biochemistry 2017 Jun;44:80-91
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Chen Y, Wang XQ, Zhang Q, Zhu JY, Li Y, Xie CF, Li XT, Wu JS, Geng SS, Zhong CY, Han HY
Nutrients 2017 Jun 3;9(6)
Nutrients 2017 Jun 3;9(6)
DACH1 suppresses breast cancer as a negative regulator of CD44.
Xu H, Yu S, Yuan X, Xiong J, Kuang D, Pestell RG, Wu K
Scientific reports 2017 Jun 28;7(1):4361
Scientific reports 2017 Jun 28;7(1):4361
S100P is associated with proliferation and migration in nasopharyngeal carcinoma.
Liu Y, Wang C, Shan X, Wu J, Liu H, Liu H, Zhang J, Xu W, Sha Z, He J, Fan J
Oncology letters 2017 Jul;14(1):525-532
Oncology letters 2017 Jul;14(1):525-532
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, Li Y, Chen Y, Wang X, Meng Y, Zhu M, Wu R, Huang C, Ma X, Geng S, Wu J, Zhong C
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Wei X, Ye J, Shang Y, Chen H, Liu S, Liu L, Wang R
Oncotarget 2017 Dec 12;8(65):109301-109318
Oncotarget 2017 Dec 12;8(65):109301-109318
Autophagy plays an important role in stemness mediation and the novel dual function of EIG121 in both autophagy and stemness regulation of endometrial carcinoma JEC cells.
Ran X, Zhou P, Zhang K
International journal of oncology 2017 Aug;51(2):644-656
International journal of oncology 2017 Aug;51(2):644-656
SLC39A4 expression is associated with enhanced cell migration, cisplatin resistance, and poor survival in non-small cell lung cancer.
Wu DM, Liu T, Deng SH, Han R, Xu Y
Scientific reports 2017 Aug 3;7(1):7211
Scientific reports 2017 Aug 3;7(1):7211
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Zhu JY, Yang X, Chen Y, Jiang Y, Wang SJ, Li Y, Wang XQ, Meng Y, Zhu MM, Ma X, Huang C, Wu R, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Sulfiredoxin May Promote Cervical Cancer Metastasis via Wnt/β-Catenin Signaling Pathway.
Lan K, Zhao Y, Fan Y, Ma B, Yang S, Liu Q, Linghu H, Wang H
International journal of molecular sciences 2017 Apr 27;18(5)
International journal of molecular sciences 2017 Apr 27;18(5)
CD44+ cancer cell-induced metastasis: A feasible neck metastasis model.
Wu TF, Chen L, Bu LL, Gao J, Zhang WF, Jia J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017 Apr 1;101:243-250
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017 Apr 1;101:243-250
Hypoxia Promotes Gastric Cancer Malignancy Partly through the HIF-1α Dependent Transcriptional Activation of the Long Non-coding RNA GAPLINC.
Liu L, Zhao X, Zou H, Bai R, Yang K, Tian Z
Frontiers in physiology 2016;7:420
Frontiers in physiology 2016;7:420
MiR-21-5p Links Epithelial-Mesenchymal Transition Phenotype with Stem-Like Cell Signatures via AKT Signaling in Keloid Keratinocytes.
Yan L, Cao R, Liu Y, Wang L, Pan B, Lv X, Jiao H, Zhuang Q, Sun X, Xiao R
Scientific reports 2016 Sep 6;6:28281
Scientific reports 2016 Sep 6;6:28281
MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer.
Vos MC, Hollemans E, Ezendam N, Feijen H, Boll D, Pijlman B, van der Putten H, Klinkhamer P, van Kuppevelt TH, van der Wurff AA, Massuger LF
Journal of ovarian research 2016 Sep 2;9(1):53
Journal of ovarian research 2016 Sep 2;9(1):53
CD44 correlates with clinicopathological characteristics and is upregulated by EGFR in breast cancer.
Xu H, Wu K, Tian Y, Liu Q, Han N, Yuan X, Zhang L, Wu GS, Wu K
International journal of oncology 2016 Oct;49(4):1343-50
International journal of oncology 2016 Oct;49(4):1343-50
Extracellular serglycin upregulates the CD44 receptor in an autocrine manner to maintain self-renewal in nasopharyngeal carcinoma cells by reciprocally activating the MAPK/β-catenin axis.
Chu Q, Huang H, Huang T, Cao L, Peng L, Shi S, Zheng L, Xu L, Zhang S, Huang J, Li X, Qian C, Huang B
Cell death & disease 2016 Nov 3;7(11):e2456
Cell death & disease 2016 Nov 3;7(11):e2456
NIBP impacts on the expression of E-cadherin, CD44 and vimentin in colon cancer via the NF-κB pathway.
Xu CY, Qin MB, Tan L, Liu SQ, Huang JA
Molecular medicine reports 2016 Jun;13(6):5379-85
Molecular medicine reports 2016 Jun;13(6):5379-85
EB-virus latent membrane protein 1 potentiates the stemness of nasopharyngeal carcinoma via preferential activation of PI3K/AKT pathway by a positive feedback loop.
Yang CF, Yang GD, Huang TJ, Li R, Chu QQ, Xu L, Wang MS, Cai MD, Zhong L, Wei HJ, Huang HB, Huang JL, Qian CN, Huang BJ
Oncogene 2016 Jun 30;35(26):3419-31
Oncogene 2016 Jun 30;35(26):3419-31
KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway.
Li L, Duan T, Wang X, Zhang RH, Zhang M, Wang S, Wang F, Wu Y, Huang H, Kang T
Scientific reports 2016 Feb 5;6:20460
Scientific reports 2016 Feb 5;6:20460
NOTCH1 inhibition enhances the efficacy of conventional chemotherapeutic agents by targeting head neck cancer stem cell.
Zhao ZL, Zhang L, Huang CF, Ma SR, Bu LL, Liu JF, Yu GT, Liu B, Gutkind JS, Kulkarni AB, Zhang WF, Sun ZJ
Scientific reports 2016 Apr 25;6:24704
Scientific reports 2016 Apr 25;6:24704
Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice.
Peng Z, Chen W, Wang L, Ye Z, Gao S, Sun X, Guo Z
International journal of clinical and experimental pathology 2015;8(3):2680-9
International journal of clinical and experimental pathology 2015;8(3):2680-9
Vorinostat protects against calcium oxalate-induced kidney injury in mice.
Wang L, Chen W, Peng Z, Liu C, Zhang C, Guo Z
Molecular medicine reports 2015 Sep;12(3):4291-4297
Molecular medicine reports 2015 Sep;12(3):4291-4297
Histochemical evidence of zoledronate inhibiting c-src expression and interfering with CD44/OPN-mediated osteoclast adhesion in the tibiae of mice.
Liu H, Cui J, Sun J, Du J, Feng W, Sun B, Li J, Han X, Liu B, Yimin, Oda K, Amizuka N, Li M
Journal of molecular histology 2015 Jun;46(3):313-23
Journal of molecular histology 2015 Jun;46(3):313-23
Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells.
Kang DW, Choi CY, Cho YH, Tian H, Di Paolo G, Choi KY, Min do S
The Journal of experimental medicine 2015 Jul 27;212(8):1219-37
The Journal of experimental medicine 2015 Jul 27;212(8):1219-37
Knock out CD44 in reprogrammed liver cancer cell C3A increases CSCs stemness and promotes differentiation.
Han S, Guo J, Liu Y, Zhang Z, He Q, Li P, Zhang M, Sun H, Li R, Li Y, Zeng W, Liu J, Lian L, Gao Y, Shen L
Oncotarget 2015 Dec 29;6(42):44452-65
Oncotarget 2015 Dec 29;6(42):44452-65
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Oncology letters 2014 May;7(5):1544-1548
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Cancer letters 2014 Mar 28;344(2):260-71
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BMC cancer 2014 Dec 10;14:928
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Biological & pharmaceutical bulletin 2012;35(11):1964-71
Biological & pharmaceutical bulletin 2012;35(11):1964-71
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 15675-1-AP(CD44 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using CD44 antibody 15675-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-CD44 (IP:15675-1-AP, 5ug; Detection:15675-1-AP 1:800) with HeLa cells lysate 2500ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 15675-1-AP(CD44 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 15675-1-AP(CD44 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CD44 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CD44. This antibody recognizes human, mouse antigen. The CD44 antibody has been validated for the following applications: ELISA, WB, IHC, IP, FC, IF analysis.
