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- References [16]
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- Immunohistochemistry [1]
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- Product number
- 17975-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17975-1-AP, RRID:AB_2242349
- Product name
- Acetylcholinesterase antibody
- Antibody type
- Polyclonal
- Description
- Acetylcholinesterase antibody (Cat. #17975-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Acetylcholine in the gingival epithelium drives the pathogenesis of periodontitis.
Malignant epithelia cells-derived spermine induces APOE+ macrophages to suppress tumor immunity in adenocarcinoma of the esophagogastric junction.
Integrating serum pharmacochemistry, network pharmacology, and metabolomics to explore the protective mechanism of Hua-Feng-Dan in ischemic stroke.
DHYZ modulates hippocampal cholinergic pathway acetylation to ameliorate cognitive deficits post-ischemic stroke in rats.
A novel dicyanoisophorone-based fluorescent probe for rapid detection of acetylcholinesterase in biological systems.
Mitochondrial respiratory complex IV deficiency recapitulates amyotrophic lateral sclerosis.
Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer.
Zexieyin formula alleviates Alzheimer's disease via post-synaptic CaMKII modulating AMPA receptor: Involved in promoting neurogenesis to strengthen synaptic plasticity in mice hippocampus.
Pyridostigmine Protects Against Diabetic Cardiomyopathy by Regulating Vagal Activity, Gut Microbiota, and Branched-Chain Amino Acid Catabolism in Diabetic Mice.
A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota.
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Near-Infrared Fluorescence Probe for Evaluating Acetylcholinesterase Activity in PC12 Cells and In Situ Tracing AChE Distribution in Zebrafish.
Quantification of heat shock protein 70 and acetylcholinesterase over a time course suggests environmental adaptation in a foundational molluscan species.
Lithium attenuates scopolamine-induced memory deficits with inhibition of GSK-3β and preservation of postsynaptic components.
Zheng Z, Lin L, Lin H, Zhou J, Wang Z, Wang Y, Chen J, Lai C, Li R, Shen Z, Zhong M, Xie C, Chen Y, Zhang X, Guo Z, Dong R, He S, Chen F
Frontiers in immunology 2025;16:1559966
Frontiers in immunology 2025;16:1559966
Acetylcholine in the gingival epithelium drives the pathogenesis of periodontitis.
Xu S, Guo J, Yang S, Cheng B, Xia J
Frontiers in cell and developmental biology 2025;13:1701252
Frontiers in cell and developmental biology 2025;13:1701252
Malignant epithelia cells-derived spermine induces APOE+ macrophages to suppress tumor immunity in adenocarcinoma of the esophagogastric junction.
Zhang Y, Liu Z, Sun H, Wang Z, Chen Y, Hu Z, Li X, Xu K, Chen Y, Xu Y, Wang C, Xu S
Frontiers in medicine 2025;12:1636699
Frontiers in medicine 2025;12:1636699
Integrating serum pharmacochemistry, network pharmacology, and metabolomics to explore the protective mechanism of Hua-Feng-Dan in ischemic stroke.
Yuan X, He X, Shu Q, Gao Y, Chen Y, Xu J, Zhang Y, Cao G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157251
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157251
DHYZ modulates hippocampal cholinergic pathway acetylation to ameliorate cognitive deficits post-ischemic stroke in rats.
Liu Z, Shi X, Xu X, Hu Y, Wen Y, Wang X, Ye L, Gong J
Brain research 2025 Nov 1;1866:149926
Brain research 2025 Nov 1;1866:149926
A novel dicyanoisophorone-based fluorescent probe for rapid detection of acetylcholinesterase in biological systems.
Gui Y, Wang J, Gou Q, Yu X, Yang Y, Wang C, Li L, Gao W, Liu W, Wang H, Shu X, Zhang Y, Shang J
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2025 Mar 15;329:125587
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2025 Mar 15;329:125587
Mitochondrial respiratory complex IV deficiency recapitulates amyotrophic lateral sclerosis.
Cheng M, Lu D, Li K, Wang Y, Tong X, Qi X, Yan C, Ji K, Wang J, Wang W, Lv H, Zhang X, Kong W, Zhang J, Ma J, Li K, Wang Y, Feng J, Wei P, Li Q, Shen C, Fu XD, Ma Y, Zhang X
Nature neuroscience 2025 Apr;28(4):748-756
Nature neuroscience 2025 Apr;28(4):748-756
Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer.
Wang J, Wei J, Pu T, Zeng A, Karthikeyan V, Bechtold B, Vo K, Chen J, Lin TP, Chang AP, Corey E, Puhr M, Klocker H, Culig Z, Bland T, Wu BJ
Cell reports. Medicine 2024 Feb 20;5(2):101388
Cell reports. Medicine 2024 Feb 20;5(2):101388
Zexieyin formula alleviates Alzheimer's disease via post-synaptic CaMKII modulating AMPA receptor: Involved in promoting neurogenesis to strengthen synaptic plasticity in mice hippocampus.
Sun Y, Zhang H, Liu R, Wang Y, Zhang X, Huang R, Zhu B, Wu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Aug;131:155802
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Aug;131:155802
Pyridostigmine Protects Against Diabetic Cardiomyopathy by Regulating Vagal Activity, Gut Microbiota, and Branched-Chain Amino Acid Catabolism in Diabetic Mice.
Yang Y, Zhao M, He X, Wu Q, Li DL, Zang WJ
Frontiers in pharmacology 2021;12:647481
Frontiers in pharmacology 2021;12:647481
A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota.
Guo Y, Zhu X, Zeng M, Qi L, Tang X, Wang D, Zhang M, Xie Y, Li H, Yang X, Chen D
Translational psychiatry 2021 May 27;11(1):328
Translational psychiatry 2021 May 27;11(1):328
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
Wang D, Zhang H, Zeng M, Tang X, Zhu X, Guo Y, Qi L, Xie Y, Zhang M, Chen D
Aging 2021 Mar 26;13(7):10240-10274
Aging 2021 Mar 26;13(7):10240-10274
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Wu X, Sheng H, Wang L, Xia P, Wang Y, Yu L, Lv W, Hu J
Aging 2021 Mar 26;13(7):10034-10057
Aging 2021 Mar 26;13(7):10034-10057
Near-Infrared Fluorescence Probe for Evaluating Acetylcholinesterase Activity in PC12 Cells and In Situ Tracing AChE Distribution in Zebrafish.
Ma J, Si T, Yan C, Li Y, Li Q, Lu X, Guo Y
ACS sensors 2020 Jan 24;5(1):83-92
ACS sensors 2020 Jan 24;5(1):83-92
Quantification of heat shock protein 70 and acetylcholinesterase over a time course suggests environmental adaptation in a foundational molluscan species.
Ravaschiere A, Cutler C, Edleson K, Halem Z, Magun H, Meckler F, Cox R
Ecotoxicology and environmental safety 2017 Aug;142:222-229
Ecotoxicology and environmental safety 2017 Aug;142:222-229
Lithium attenuates scopolamine-induced memory deficits with inhibition of GSK-3β and preservation of postsynaptic components.
Wu YY, Wang X, Tan L, Liu D, Liu XH, Wang Q, Wang JZ, Zhu LQ
Journal of Alzheimer's disease : JAD 2013;37(3):515-27
Journal of Alzheimer's disease : JAD 2013;37(3):515-27
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 17975-1-AP(ACHE antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACHE antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ACHE. This antibody recognizes human,mouse,rat antigen. The ACHE antibody has been validated for the following applications: ELISA, WB, IHC analysis.
