Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 60171-1-Ig - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60171-1-Ig, RRID:AB_10693634
- Product name
- ALDH1A1 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated ALDH1A1 antibody (Cat. #60171-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1A10A2
- Vial size
- 20ul, 150ul
Submitted references AG1295 Attenuates High-Glucose-Induced Proliferation, Migration, Phenotype Transition, and Interleukin-6 Expression in Human Corneal Stromal Fibroblasts.
3D Differentiation of Bone-Marrow Derived Mesenchymal Stromal Cells into the Keratocyte Lineage for Corneal Bioprinting.
ONECUT2-driven activation of ADAMTS14 boosts colorectal cancer stemness via Wnt pathway.
SLC4A7 suppresses lung adenocarcinoma oncogenesis by reducing lactate transport and protein lactylation.
A positive feedback loop of OTUD1 and c-Jun driven by leptin expedites stemness maintenance in ovarian cancer.
Lfng-expressing centroacinar cell is a unique cell-of-origin for p53 deficient pancreatic cancer.
Propofol Inhibits the Stem Characteristics and Tumor Growth of NSCLC by Altering the Expression and Localization of HDAC1.
E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent manner.
Programmed death-ligand 1 regulates ameloblastoma growth and recurrence.
Perirenal adipose tissue contains a subpopulation of cold-inducible adipocytes derived from brown-to-white conversion.
Identification and Validation of a Prognostic Signature Derived from the Cancer Stem Cells for Oral Squamous Cell Carcinoma.
Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer.
Oncogenic fusion of CD63-BCAR4 contributes cancer stem cell-like properties via ALDH1 activity.
Modification of lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression.
microRNA-17 is a tumor suppressor in oral squamous cell carcinoma and is repressed by LSD1.
SPDEF enhances cancer stem cell-like properties and tumorigenesis through directly promoting GALNT7 transcription in luminal breast cancer.
Targeting ALDH1A1 to induce Necroptosis in Nasopharyngeal Carcinoma.
Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.
lncRNA TPTEP1 inhibits stemness and radioresistance of glioma through miR‑106a‑5p‑mediated P38 MAPK signaling.
Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice.
The ionophore antibiotic gramicidin A inhibits pancreatic cancer stem cells associated with CD47 down-regulation.
Garcinol from Garcinia indica Downregulates Cancer Stem-like Cell Biomarker ALDH1A1 in Nonsmall Cell Lung Cancer A549 Cells through DDIT3 Activation.
Zheng Y, Jiang H, Wang J, Zhang Q, Wan Q, Wang Y
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2026 Mar 18;:10807683261433333
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2026 Mar 18;:10807683261433333
3D Differentiation of Bone-Marrow Derived Mesenchymal Stromal Cells into the Keratocyte Lineage for Corneal Bioprinting.
Taoum A, Friede R, Thaden O, Rachynskyi O, Frank A, Wang M, Dehli F, Fuest M, Duarte Campos D
Advanced healthcare materials 2025 Nov;14(28):e2405073
Advanced healthcare materials 2025 Nov;14(28):e2405073
ONECUT2-driven activation of ADAMTS14 boosts colorectal cancer stemness via Wnt pathway.
Jiang Y, Tan X
Human cell 2025 Nov 12;39(1):7
Human cell 2025 Nov 12;39(1):7
SLC4A7 suppresses lung adenocarcinoma oncogenesis by reducing lactate transport and protein lactylation.
Yan H, He Q, Gao Y, He X, Luo H, Shao L, Dong J, Li F
International journal of oncology 2025 May;66(5)
International journal of oncology 2025 May;66(5)
A positive feedback loop of OTUD1 and c-Jun driven by leptin expedites stemness maintenance in ovarian cancer.
Wang J, Yang F, Chen Y, Xing Y, Huang J, Cao J, Xiong J, Liu Y, Zhao Q, Luo M, Xiong J, Fan G, Lyu Q, Li F, Zhang W
Oncogene 2025 Jun;44(22):1731-1745
Oncogene 2025 Jun;44(22):1731-1745
Lfng-expressing centroacinar cell is a unique cell-of-origin for p53 deficient pancreatic cancer.
Chung WC, Zhang S, Atfi A, Xu K
Oncogene 2025 Feb;44(6):348-362
Oncogene 2025 Feb;44(6):348-362
Propofol Inhibits the Stem Characteristics and Tumor Growth of NSCLC by Altering the Expression and Localization of HDAC1.
Liu M, Leng H, Wang J, Zhang Y, Gong H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 31;39(24):e71337
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 31;39(24):e71337
E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent manner.
Li J, Chen Y, Wang J, Liu L, Qadir J, Xie D, Wan X, Luo Y, Xian J, Ye T
Journal of experimental & clinical cancer research : CR 2025 Aug 30;44(1):261
Journal of experimental & clinical cancer research : CR 2025 Aug 30;44(1):261
Programmed death-ligand 1 regulates ameloblastoma growth and recurrence.
Zhang L, Lin H, Liang J, Liu X, Zhang C, Man Q, Li R, Zhao Y, Liu B
International journal of oral science 2025 Apr 16;17(1):29
International journal of oral science 2025 Apr 16;17(1):29
Perirenal adipose tissue contains a subpopulation of cold-inducible adipocytes derived from brown-to-white conversion.
Zhang H, Li Y, Ibáñez CF, Xie M
eLife 2024 Mar 12;13
eLife 2024 Mar 12;13
Identification and Validation of a Prognostic Signature Derived from the Cancer Stem Cells for Oral Squamous Cell Carcinoma.
Shi M, Huang K, Wei J, Wang S, Yang W, Wang H, Li Y
International journal of molecular sciences 2024 Jan 14;25(2)
International journal of molecular sciences 2024 Jan 14;25(2)
Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer.
Liu CC, Chen L, Cai YW, Chen YF, Liu YM, Zhou YJ, Shao ZM, Yu KD
Cell reports. Medicine 2024 Feb 20;5(2):101396
Cell reports. Medicine 2024 Feb 20;5(2):101396
Oncogenic fusion of CD63-BCAR4 contributes cancer stem cell-like properties via ALDH1 activity.
Bae K, Kim DE, Kim JH, Lee JY, Yoon KA
Molecular carcinogenesis 2024 Dec;63(12):2282-2290
Molecular carcinogenesis 2024 Dec;63(12):2282-2290
Modification of lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression.
Zhang Z, Wang Y, Liang Z, Meng Z, Zhang X, Ma G, Chen Y, Zhang M, Su Y, Li Z, Liang Y, Niu H
iScience 2023 Nov 17;26(11):108142
iScience 2023 Nov 17;26(11):108142
microRNA-17 is a tumor suppressor in oral squamous cell carcinoma and is repressed by LSD1.
Wangzhou K, Fu W, Li M, Lu Z, Lai Z, Liu C, Tan Y, Hao C
Oral diseases 2023 Mar;29(2):491-504
Oral diseases 2023 Mar;29(2):491-504
SPDEF enhances cancer stem cell-like properties and tumorigenesis through directly promoting GALNT7 transcription in luminal breast cancer.
Li J, Wan X, Xie D, Yuan H, Pei Q, Luo Y, Chen Y, Xian J, Ye T
Cell death & disease 2023 Aug 26;14(8):569
Cell death & disease 2023 Aug 26;14(8):569
Targeting ALDH1A1 to induce Necroptosis in Nasopharyngeal Carcinoma.
Wang H, Zhan Y, Peng S, Fan S, Wang W
Journal of Cancer 2022;13(14):3515-3525
Journal of Cancer 2022;13(14):3515-3525
Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.
Xin M, Gao Q, Xiang X, Xu J, Jiao Y, Li X, Zhang X, Jia X
Frontiers in pharmacology 2022;13:890974
Frontiers in pharmacology 2022;13:890974
lncRNA TPTEP1 inhibits stemness and radioresistance of glioma through miR‑106a‑5p‑mediated P38 MAPK signaling.
Tang T, Wang LX, Yang ML, Zhang RM
Molecular medicine reports 2020 Dec;22(6):4857-4867
Molecular medicine reports 2020 Dec;22(6):4857-4867
Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice.
Zhou H, Su J, Hu X, Zhou C, Li H, Chen Z, Xiao Q, Wang B, Wu W, Sun Y, Zhou Y, Tang C, Liu F, Wang L, Feng C, Liu M, Li S, Zhang Y, Xu H, Yao H, Shi L, Yang H
Cell 2020 Apr 30;181(3):590-603.e16
Cell 2020 Apr 30;181(3):590-603.e16
The ionophore antibiotic gramicidin A inhibits pancreatic cancer stem cells associated with CD47 down-regulation.
Wang RQ, Geng J, Sheng WJ, Liu XJ, Jiang M, Zhen YS
Cancer cell international 2019;19:145
Cancer cell international 2019;19:145
Garcinol from Garcinia indica Downregulates Cancer Stem-like Cell Biomarker ALDH1A1 in Nonsmall Cell Lung Cancer A549 Cells through DDIT3 Activation.
Wang J, Wang L, Ho CT, Zhang K, Liu Q, Zhao H
Journal of agricultural and food chemistry 2017 May 10;65(18):3675-3683
Journal of agricultural and food chemistry 2017 May 10;65(18):3675-3683
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The ALDH1A1 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human ALDH1A1. This antibody recognizes human, mouse, rat antigen. The ALDH1A1 antibody has been validated for the following applications: ELISA, WB analysis.