GTX108370

Maruhashi R, Akizuki R, Sato T, Matsunaga T, Endo S, Yamaguchi M, Yamazaki Y, Sakai H, Ikari A
Biochimica et biophysica acta. Molecular cell research 2018 Mar;1865(3):470-479

Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway.

Yeh YH, Hsiao HF, Yeh YC, Chen TW, Li TK
Journal of experimental & clinical cancer research : CR 2018 Mar 27;37(1):70

Modulation of the mRNA-binding protein HuR as a novel reversal mechanism of epirubicin-triggered multidrug resistance in colorectal cancer cells.

Lin GL, Ting HJ, Tseng TC, Juang V, Lo YL
PloS one 2017;12(10):e0185625

Peri-foci adipose-derived stem cells promote chemoresistance in breast cancer.

Yeh WL, Tsai CF, Chen DR
Stem cell research & therapy 2017 Jul 27;8(1):177

PGRMC1 contributes to doxorubicin-induced chemoresistance in MES-SA uterine sarcoma.

Lin ST, May EW, Chang JF, Hu RY, Wang LH, Chan HL
Cellular and molecular life sciences : CMLS 2015 Jun;72(12):2395-409

Mitochondrial proteomics with siRNA knockdown to reveal ACAT1 and MDH2 in the development of doxorubicin-resistant uterine cancer.

Lo YW, Lin ST, Chang SJ, Chan CH, Lyu KW, Chang JF, May EW, Lin DY, Chou HC, Chan HL
Journal of cellular and molecular medicine 2015 Apr;19(4):744-59

Mesenchymal stem cell-induced doxorubicin resistance in triple negative breast cancer.

Chen DR, Lu DY, Lin HY, Yeh WL
BioMed research international 2014;2014:532161

Carfilzomib and oprozomib synergize with histone deacetylase inhibitors in head and neck squamous cell carcinoma models of acquired resistance to proteasome inhibitors.

Zang Y, Kirk CJ, Johnson DE
Cancer biology & therapy 2014 Sep;15(9):1142-52

Nuclear proteomics with XRCC3 knockdown to reveal the development of doxorubicin-resistant uterine cancer.

Chang JF, Lin ST, Hung E, Lu YL, Soon May EW, Lo YW, Chou HC, Chan HL
Toxicological sciences : an official journal of the Society of Toxicology 2014 Jun;139(2):396-406

Involvement of p38 mitogen-activated protein kinase in acquired gemcitabine-resistant human urothelial carcinoma sublines

Kao Y, Hsu W, Hu H, Hsu S, Lin C, Chiu C, Lu C, Hour T, Pu Y, Huang A
The Kaohsiung Journal of Medical Sciences 2014 July;30(7):323-330

Proteomic analysis of the proteins that are associated with the resistance to paclitaxel in human breast cancer cells.

Chen S, Dong Q, Hu S, Cai J, Zhang W, Sun J, Wang T, Xie J, He H, Xing J, Lu J, Dong Y
Molecular bioSystems 2014 Feb;10(2):294-303

Proteomic analysis of proteins responsible for the development of doxorubicin resistance in human uterine cancer cells.

Lin ST, Chou HC, Chang SJ, Chen YW, Lyu PC, Wang WC, Chang MD, Chan HL
Journal of proteomics 2012 Oct 22;75(18):5822-47

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Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Sample (10 ?g of whole cell lysate) A: Hep3B 6% SDS PAGE GTX108370 diluted at 1:2500 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Unboiled HepG2 whole cell and membrane extracts (30 ?g) were separated by 5% SDS-PAGE, and the membrane was blotted with P Glycoprotein antibody (GTX108370) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: P Glycoprotein antibody detects P Glycoprotein protein at cytoplasm by immunofluorescent analysis.Sample: HeLa cells were fixed in ice-cold MeOH for 5 min.Green: P Glycoprotein protein stained by P Glycoprotein antibody (GTX108370) diluted at 1:500.Blue: Hoechst 33342 staining.