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LearnPAB17319
antibody from Abnova Corporation
Targeting: MTOR
FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB17319 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB17319, RRID:AB_10643615
- Product name
- MTOR polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of MTOR.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status.
Alcohol impairs leucine-mediated phosphorylation of 4E-BP1, S6K1, eIF4G, and mTOR in skeletal muscle.
mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.
Cheng SW, Fryer LG, Carling D, Shepherd PR
The Journal of biological chemistry 2004 Apr 16;279(16):15719-22
The Journal of biological chemistry 2004 Apr 16;279(16):15719-22
Alcohol impairs leucine-mediated phosphorylation of 4E-BP1, S6K1, eIF4G, and mTOR in skeletal muscle.
Lang CH, Frost RA, Deshpande N, Kumar V, Vary TC, Jefferson LS, Kimball SR
American journal of physiology. Endocrinology and metabolism 2003 Dec;285(6):E1205-15
American journal of physiology. Endocrinology and metabolism 2003 Dec;285(6):E1205-15
mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.
Hannan KM, Brandenburger Y, Jenkins A, Sharkey K, Cavanaugh A, Rothblum L, Moss T, Poortinga G, McArthur GA, Pearson RB, Hannan RD
Molecular and cellular biology 2003 Dec;23(23):8862-77
Molecular and cellular biology 2003 Dec;23(23):8862-77
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from K-562 cells, using MTOR polyclonal antibody (Cat # PAB17319).Peptide "+" means "with peptide blocking".
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human brain tissue using MTOR polyclonal antibody (Cat # PAB17319).Peptide "+" means "with peptide blocking".
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
