Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [2]
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- Product number
- ABIN258372 - Provider product page

- Provider
- antibodies-online
- Product name
- anti-Abhydrolase Domain Containing 5 (ABHD5) (AA 200-300), (Internal Region) antibody
- Antibody type
- Polyclonal
- Description
- IgG purified
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Internal Region, AA 200-300
- Vial size
- 0.1 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Prior Endurance Training Enhances Beta-Adrenergic Signaling in Epidydimal Adipose from Mice Fed a High-Fat Diet.
Lipid droplet dynamics and insulin sensitivity upon a 5-day high-fat diet in Caucasians and South Asians.
Increases in skeletal muscle ATGL and its inhibitor G0S2 following 8 weeks of endurance training in metabolically different rat skeletal muscles.
Lipid mixtures containing a very high proportion of saturated fatty acids only modestly impair insulin signaling in cultured muscle cells.
Characterization of lipolytic inhibitor G(0)/G(1) switch gene-2 protein (G0S2) expression in male Sprague-Dawley rat skeletal muscle compared to relative content of adipose triglyceride lipase (ATGL) and comparitive gene identification-58 (CGI-58).
A maternal high fat diet has long-lasting effects on skeletal muscle lipid and PLIN protein content in rat offspring at young adulthood.
Transgenic CGI-58 expression in macrophages alleviates the atherosclerotic lesion development in ApoE knockout mice.
Skeletal muscle PLIN3 and PLIN5 are serine phosphorylated at rest and following lipolysis during adrenergic or contractile stimulation.
Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity.
Contraction-induced lipolysis is not impaired by inhibition of hormone-sensitive lipase in skeletal muscle.
IL-6 and epinephrine have divergent fiber type effects on intramuscular lipolysis.
PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans.
Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1.
Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity.
Skeletal muscle PLIN proteins, ATGL and CGI-58, interactions at rest and following stimulated contraction.
Valsartan improves adipose tissue function in humans with impaired glucose metabolism: a randomized placebo-controlled double-blind trial.
Perilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels.
Alternative splicing and developmental and hormonal regulation of porcine comparative gene identification-58 (CGI-58) mRNA.
Paradoxical increase in TAG and DAG content parallel the insulin sensitizing effect of unilateral DGAT1 overexpression in rat skeletal muscle.
Skeletal muscle lipase content and activity in obesity and type 2 diabetes.
Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training.
CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome.
Snook LA, Trottier SK, Worndl EA, Bombardier E, Tupling AR, MacPherson REK
Obesity (Silver Spring, Md.) 2017 Oct;25(10):1699-1706
Obesity (Silver Spring, Md.) 2017 Oct;25(10):1699-1706
Lipid droplet dynamics and insulin sensitivity upon a 5-day high-fat diet in Caucasians and South Asians.
Gemmink A, Bakker LE, Guigas B, Kornips E, Schaart G, Meinders AE, Jazet IM, Hesselink MK
Scientific reports 2017 Feb 14;7:42393
Scientific reports 2017 Feb 14;7:42393
Increases in skeletal muscle ATGL and its inhibitor G0S2 following 8 weeks of endurance training in metabolically different rat skeletal muscles.
Turnbull PC, Longo AB, Ramos SV, Roy BD, Ward WE, Peters SJ
American journal of physiology. Regulatory, integrative and comparative physiology 2016 Jan 15;310(2):R125-33
American journal of physiology. Regulatory, integrative and comparative physiology 2016 Jan 15;310(2):R125-33
Lipid mixtures containing a very high proportion of saturated fatty acids only modestly impair insulin signaling in cultured muscle cells.
Newsom SA, Everett AC, Park S, Van Pelt DW, Hinko A, Horowitz JF
PloS one 2015;10(3):e0120871
PloS one 2015;10(3):e0120871
Characterization of lipolytic inhibitor G(0)/G(1) switch gene-2 protein (G0S2) expression in male Sprague-Dawley rat skeletal muscle compared to relative content of adipose triglyceride lipase (ATGL) and comparitive gene identification-58 (CGI-58).
Turnbull PC, Ramos SV, MacPherson RE, Roy BD, Peters SJ
PloS one 2015;10(3):e0120136
PloS one 2015;10(3):e0120136
A maternal high fat diet has long-lasting effects on skeletal muscle lipid and PLIN protein content in rat offspring at young adulthood.
MacPherson RE, Castelli LM, Miotto PM, Frendo-Cumbo S, Milburn A, Roy BD, LeBlanc PJ, Ward WE, Peters SJ
Lipids 2015 Feb;50(2):205-17
Lipids 2015 Feb;50(2):205-17
Transgenic CGI-58 expression in macrophages alleviates the atherosclerotic lesion development in ApoE knockout mice.
Xie P, Zeng X, Xiao J, Sun B, Yang D
Biochimica et biophysica acta 2014 Dec;1841(12):1683-90
Biochimica et biophysica acta 2014 Dec;1841(12):1683-90
Skeletal muscle PLIN3 and PLIN5 are serine phosphorylated at rest and following lipolysis during adrenergic or contractile stimulation.
Macpherson RE, Vandenboom R, Roy BD, Peters SJ
Physiological reports 2013 Sep;1(4):e00084
Physiological reports 2013 Sep;1(4):e00084
Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity.
Sitnick MT, Basantani MK, Cai L, Schoiswohl G, Yazbeck CF, Distefano G, Ritov V, DeLany JP, Schreiber R, Stolz DB, Gardner NP, Kienesberger PC, Pulinilkunnil T, Zechner R, Goodpaster BH, Coen P, Kershaw EE
Diabetes 2013 Oct;62(10):3350-61
Diabetes 2013 Oct;62(10):3350-61
Contraction-induced lipolysis is not impaired by inhibition of hormone-sensitive lipase in skeletal muscle.
Alsted TJ, Ploug T, Prats C, Serup AK, Høeg L, Schjerling P, Holm C, Zimmermann R, Fledelius C, Galbo H, Kiens B
The Journal of physiology 2013 Oct 15;591(20):5141-55
The Journal of physiology 2013 Oct 15;591(20):5141-55
IL-6 and epinephrine have divergent fiber type effects on intramuscular lipolysis.
Macdonald TL, Wan Z, Frendo-Cumbo S, Dyck DJ, Wright DC
Journal of applied physiology (Bethesda, Md. : 1985) 2013 Nov;115(10):1457-63
Journal of applied physiology (Bethesda, Md. : 1985) 2013 Nov;115(10):1457-63
PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans.
Koves TR, Sparks LM, Kovalik JP, Mosedale M, Arumugam R, DeBalsi KL, Everingham K, Thorne L, Phielix E, Meex RC, Kien CL, Hesselink MK, Schrauwen P, Muoio DM
Journal of lipid research 2013 Feb;54(2):522-34
Journal of lipid research 2013 Feb;54(2):522-34
Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1.
Mowers J, Uhm M, Reilly SM, Simon J, Leto D, Chiang SH, Chang L, Saltiel AR
eLife 2013 Dec 24;2:e01119
eLife 2013 Dec 24;2:e01119
Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity.
Bosma M, Sparks LM, Hooiveld GJ, Jorgensen JA, Houten SM, Schrauwen P, Kersten S, Hesselink MK
Biochimica et biophysica acta 2013 Apr;1831(4):844-52
Biochimica et biophysica acta 2013 Apr;1831(4):844-52
Skeletal muscle PLIN proteins, ATGL and CGI-58, interactions at rest and following stimulated contraction.
MacPherson RE, Ramos SV, Vandenboom R, Roy BD, Peters SJ
American journal of physiology. Regulatory, integrative and comparative physiology 2013 Apr 15;304(8):R644-50
American journal of physiology. Regulatory, integrative and comparative physiology 2013 Apr 15;304(8):R644-50
Valsartan improves adipose tissue function in humans with impaired glucose metabolism: a randomized placebo-controlled double-blind trial.
Goossens GH, Moors CC, van der Zijl NJ, Venteclef N, Alili R, Jocken JW, Essers Y, Cleutjens JP, Clément K, Diamant M, Blaak EE
PloS one 2012;7(6):e39930
PloS one 2012;7(6):e39930
Perilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels.
Bosma M, Hesselink MK, Sparks LM, Timmers S, Ferraz MJ, Mattijssen F, van Beurden D, Schaart G, de Baets MH, Verheyen FK, Kersten S, Schrauwen P
Diabetes 2012 Nov;61(11):2679-90
Diabetes 2012 Nov;61(11):2679-90
Alternative splicing and developmental and hormonal regulation of porcine comparative gene identification-58 (CGI-58) mRNA.
Li X, Suh Y, Kim E, Moeller SJ, Lee K
Journal of animal science 2012 Dec;90(12):4346-54
Journal of animal science 2012 Dec;90(12):4346-54
Paradoxical increase in TAG and DAG content parallel the insulin sensitizing effect of unilateral DGAT1 overexpression in rat skeletal muscle.
Timmers S, de Vogel-van den Bosch J, Hesselink MK, van Beurden D, Schaart G, Ferraz MJ, Losen M, Martinez-Martinez P, De Baets MH, Aerts JM, Schrauwen P
PloS one 2011 Jan 14;6(1):e14503
PloS one 2011 Jan 14;6(1):e14503
Skeletal muscle lipase content and activity in obesity and type 2 diabetes.
Jocken JW, Moro C, Goossens GH, Hansen D, Mairal A, Hesselink MK, Langin D, van Loon LJ, Blaak EE
The Journal of clinical endocrinology and metabolism 2010 Dec;95(12):5449-53
The Journal of clinical endocrinology and metabolism 2010 Dec;95(12):5449-53
Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training.
Alsted TJ, Nybo L, Schweiger M, Fledelius C, Jacobsen P, Zimmermann R, Zechner R, Kiens B
American journal of physiology. Endocrinology and metabolism 2009 Mar;296(3):E445-53
American journal of physiology. Endocrinology and metabolism 2009 Mar;296(3):E445-53
CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome.
Yamaguchi T, Omatsu N, Matsushita S, Osumi T
The Journal of biological chemistry 2004 Jul 16;279(29):30490-7
The Journal of biological chemistry 2004 Jul 16;279(29):30490-7
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image

- Experimental details
- WB