ABIN499846

antibody from antibodies-online

Targeting: CFLAR c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN499846

Provider

antibodies-online

Product name

anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (N-Term) antibody

Antibody type

Polyclonal

Antigen

Bacteria FLIP (N-Terminus) Peptide (ABIN499845)

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.

References

Submitted references

Casper is a FADD- and caspase-related inducer of apoptosis.

Shu HB, Halpin DR, Goeddel DV
Immunity 1997 Jun;6(6):751-63

---

I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis.

Hu S, Vincenz C, Ni J, Gentz R, Dixit VM
The Journal of biological chemistry 1997 Jul 11;272(28):17255-7

---

Inhibition of death receptor signals by cellular FLIP.

Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schröter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J
Nature 1997 Jul 10;388(6638):190-5

---

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors.

Thome M, Schneider P, Hofmann K, Fickenscher H, Meinl E, Neipel F, Mattmann C, Burns K, Bodmer JL, Schröter M, Scaffidi C, Krammer PH, Peter ME, Tschopp J
Nature 1997 Apr 3;386(6624):517-21

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of FLIP in K562 cell lysate with AP30341PU-N FLIP antibody at (A) 1 and (B) 2 ?g/ml.

Immunocytochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Immunocytochemistry of FLIP in HeLa cells with AP30341PU-N FLIP antibody at 5 ?g/ml.