Explore
Validate
Learn
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN358152 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (pSer272) antibody
- Antibody type
- Polyclonal
- Description
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer272
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Catalysis and function of the p38 alpha.MK2a signaling complex.
Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme.
Structure of mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 suggests a bifunctional switch that couples kinase activation with nuclear export.
Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells.
5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases.
Lukas SM, Kroe RR, Wildeson J, Peet GW, Frego L, Davidson W, Ingraham RH, Pargellis CA, Labadia ME, Werneburg BG
Biochemistry 2004 Aug 10;43(31):9950-60
Biochemistry 2004 Aug 10;43(31):9950-60
Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme.
Underwood KW, Parris KD, Federico E, Mosyak L, Czerwinski RM, Shane T, Taylor M, Svenson K, Liu Y, Hsiao CL, Wolfrom S, Maguire M, Malakian K, Telliez JB, Lin LL, Kriz RW, Seehra J, Somers WS, Stahl ML
Structure (London, England : 1993) 2003 Jun;11(6):627-36
Structure (London, England : 1993) 2003 Jun;11(6):627-36
Structure of mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 suggests a bifunctional switch that couples kinase activation with nuclear export.
Meng W, Swenson LL, Fitzgibbon MJ, Hayakawa K, Ter Haar E, Behrens AE, Fulghum JR, Lippke JA
The Journal of biological chemistry 2002 Oct 4;277(40):37401-5
The Journal of biological chemistry 2002 Oct 4;277(40):37401-5
Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells.
Han Q, Leng J, Bian D, Mahanivong C, Carpenter KA, Pan ZK, Han J, Huang S
The Journal of biological chemistry 2002 Dec 13;277(50):48379-85
The Journal of biological chemistry 2002 Dec 13;277(50):48379-85
5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases.
Werz O, Klemm J, Samuelsson B, Rådmark O
Proceedings of the National Academy of Sciences of the United States of America 2000 May 9;97(10):5261-6
Proceedings of the National Academy of Sciences of the United States of America 2000 May 9;97(10):5261-6
No comments: Submit comment
No validations: Submit validation data