ABIN307157

antibody from antibodies-online

Targeting: GPC3 DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN307157

Provider

antibodies-online

Product name

anti-Glypican 3 (GPC3) antibody

Antibody type

Polyclonal

Antigen

Other

Reactivity

Human

Host

Sheep

Isotype

IgG

Vial size

500 µg

Storage

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

References

Submitted references

HLA-A2 and -A24-restricted glypican-3-derived peptide vaccine induces specific CTLs: preclinical study using mice.

Motomura Y, Ikuta Y, Kuronuma T, Komori H, Ito M, Tsuchihara M, Tsunoda Y, Shirakawa H, Baba H, Nishimura Y, Kinoshita T, Nakatsura T
International journal of oncology 2008 May;32(5):985-90

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Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding.

Capurro MI, Xu P, Shi W, Li F, Jia A, Filmus J
Developmental cell 2008 May;14(5):700-11

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Value of glypican 3 immunostaining in the diagnosis of hepatocellular carcinoma on needle biopsy.

Anatelli F, Chuang ST, Yang XJ, Wang HL
American journal of clinical pathology 2008 Aug;130(2):219-23

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Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma.

Lai JP, Sandhu DS, Yu C, Han T, Moser CD, Jackson KK, Guerrero RB, Aderca I, Isomoto H, Garrity-Park MM, Zou H, Shire AM, Nagorney DM, Sanderson SO, Adjei AA, Lee JS, Thorgeirsson SS, Roberts LR
Hepatology (Baltimore, Md.) 2008 Apr;47(4):1211-22

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Immunohistochemical staining using GPC3 antibody , used at 1:20 dilution. Sections heated for 10 minutes with 10 mM sodium citrate.