Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- ELISA [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN396214 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Abhydrolase Domain Containing 5 (ABHD5) (AA 240-343) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 240-343
- Isotype
- IgG
- Antibody clone number
- 4B12
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references High frequency of ETFDH c.250G>A mutation in Taiwanese patients with late-onset lipid storage myopathy.
Chanarin-Dorfman syndrome: deficiency in CGI-58, a lipid droplet-bound coactivator of lipase.
Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5.
CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid.
CGI-58 is an alpha/beta-hydrolase within lipid transporting lamellar granules of differentiated keratinocytes.
Lan MY, Fu MH, Liu YF, Huang CC, Chang YY, Liu JS, Peng CH, Chen SS
Clinical genetics 2010 Dec;78(6):565-9
Clinical genetics 2010 Dec;78(6):565-9
Chanarin-Dorfman syndrome: deficiency in CGI-58, a lipid droplet-bound coactivator of lipase.
Yamaguchi T, Osumi T
Biochimica et biophysica acta 2009 Jun;1791(6):519-23
Biochimica et biophysica acta 2009 Jun;1791(6):519-23
Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5.
Schweiger M, Lass A, Zimmermann R, Eichmann TO, Zechner R
American journal of physiology. Endocrinology and metabolism 2009 Aug;297(2):E289-96
American journal of physiology. Endocrinology and metabolism 2009 Aug;297(2):E289-96
CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid.
Ghosh AK, Ramakrishnan G, Chandramohan C, Rajasekharan R
The Journal of biological chemistry 2008 Sep 5;283(36):24525-33
The Journal of biological chemistry 2008 Sep 5;283(36):24525-33
CGI-58 is an alpha/beta-hydrolase within lipid transporting lamellar granules of differentiated keratinocytes.
Akiyama M, Sakai K, Takayama C, Yanagi T, Yamanaka Y, McMillan JR, Shimizu H
The American journal of pathology 2008 Nov;173(5):1349-60
The American journal of pathology 2008 Nov;173(5):1349-60
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
