313103

antibody from BioLegend

Targeting: ICAM1 BB2, CD54

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

313103

Provider

BioLegend

Product name

FITC anti-human CD54

Antibody type

Monoclonal

Antigen

Burkittt's lymphoma cell line Raji

Description

CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 on the cell surface is potently upregulated by activation; a soluble form of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen.

Reactivity

Human, Rat, Bovine, Simian

Host

Mouse

Conjugate

Green dye

Isotype

IgG

Vial size

25 tests

Storage

The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.