313705

antibody from BioLegend
Targeting: CCR5 CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Provider product page for 313705

Antibody data

Product number
313705 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#313705, RRID:AB_345305
Product name
FITC anti-human CD195 (CCR5)
Antibody type
Monoclonal
Antigen
CHO cells transfected with human CCR5
Description
CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
Reactivity
Human
Host
Rat
Conjugate
Green dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
CCR5 protein structure - 313705 shown in red.