326704

antibody from BioLegend
Targeting: FZD4 CD344, EVR1
Provider product page for 326704

Antibody data

Product number
326704 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#326704, RRID:AB_2107361
Product name
Biotin anti-human CD349 (Frizzled-9)
Antibody type
Monoclonal
Antigen
WERI-RB-1 retinoblastoma cells
Description
CD349 is a member of the Frizzled family, known as Frizzled-9 (Fz9, FZD9, hFz9, or FzE6) which was originally described as FZD3. Ten frizzled member have been identified in humans. FZD9 is a seven transmembrane G-protein-coupled receptor (GPCR), a receptor for Wnt proteins. It is involved in the activation of Wnt/β-catenin pathway (canonic Wnt signaling). FZD9 is predominately expressed in fetal and adult brain, testis, eye, skeletal muscle and kidney and is also expressed on Mesenchymal stem cells, and neural precursor cells. Frizzled proteins play important roles in controlling cell fate, proliferation, migration, tissue architecture and organogenesis during embryonic development and in adult organisms. FZD9 is an important factor for nervous system development and is critical for hippocampal development.
Reactivity
Human
Host
Mouse
Conjugate
Biotin
Isotype
IgM
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C. Do not freeze.
FZD4 protein structure - 326704 shown in red.