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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 331522 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#331522, RRID:AB_10720182
- Product name
- Alexa Fluor® 488 anti-human CD1c [L161]
- Antibody type
- Monoclonal
- Antigen
- CD1c
- Description
- CD1c, also known as R7 or M241, is a 43 kD member of the five CD1 antigens (CD1a-e) in human. The CD1 molecules are type I glycoprotein with structural similarities to MHC class I and a non-covalent associated with β2-microglobulin, belonging to Ig superfamily. CD1c is expressed on cortical thymocytes, Langerhans cells, dendritic cells, and a subset of B cells. It has been reported that CD1c is also expressed on mature T cells with tightly regulated manner. The function of CD1c is involved in antigen-presentation of glycolipids. It may also act in T cells as an immune regulatory molecule.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes were stained with CD19 APC and CD1c (clone L161) Alexa Fluor® 488 (top) or Mouse IgG1, κ Alexa Fluor® 488 isotype control (bottom).
- Conjugate
- Green dye
