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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 343507 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#343507, RRID:AB_1877134
- Product name
- Alexa Fluor® 647 anti-human CD34 [581]
- Antibody type
- Monoclonal
- Antigen
- CD34
- Description
- CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 25 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood leukocytes stained with 581 Alexa Fluor® 647 and CD45 (HI30) FITC (top) or mIgG1,κ isotype control Alexa Fluor® 647 and CD45 (HI30) FITC (bottom). Cytograms were gated to display CD14 negative lymphocyte population.
- Conjugate
- Red dye
