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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 343511 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#343511, RRID:AB_1877198
- Product name
- Pacific Blue™ anti-human CD34 [581]
- Antibody type
- Monoclonal
- Antigen
- CD34
- Description
- CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Blue dye
- Isotype
- IgG
- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human peripheral blood leukocytes stained with CD34 Pacific Blue™ (clone 581) or mouse IgG1, κ Pacific Blue™ isotype control and costained with CD45 FITC, CD14 PE and 7-AAD, then analyzed via gating on total live and CD14 negative lymphocyte population.
- Conjugate
- Blue dye
