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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 343609 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#343609, RRID:AB_11147951
- Product name
- Brilliant Violet 421™ anti-human CD34 [561]
- Antibody type
- Monoclonal
- Antigen
- CD34
- Description
- CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophophoprotein with an approximate molecular weight of 105-120 kD. It is selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue. CD34 is a commonly used marker for identifying human hematopoietic stem/progenitor cells. Based on different sensitivities, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Blue dye
- Isotype
- IgG
- Vial size
- 25 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood mononuclear cells were stained with CD14 PE, CD45 PerCP/Cy5.5, and CD34 (clone 561) Brilliant Violet 421™ (top) or mouse IgG2a Brilliant Violet 421™ isotype control (bottom). Dot plots are from gated on CD14-negative cell population.
- Conjugate
- Blue dye
