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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- 620802 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#620802, RRID:AB_2085644
- Product name
- Purified anti-CRP (C-reactive protein)
- Antibody type
- Polyclonal
- Antigen
- Recombinant (partial)
- Description
- CRP (C-reactive protein) is a member of the pentaxin family. CRP exists as a homopentamer in a discoid arrangement (noncovalently attached). Individual subunits are approximately 24 kD, the molecular weight of the entire molecule is approximately 120 kD CRP is secreted and can be found in plasma. This protein promotes agglutination, phagocytosis, and complement fixation through Ca2+-dependent binding to phosphorylcholine. CRP is thought to scavenge nuclear material released from damaged circulating cells. CRP is the major protein involved in acute phase response to pathogens; both CRP and degradation products of CRP act as anti-inflammatory agents. CRP has been shown to interact with both DNA and histones. The Poly6208 antibody recognizes human CRP and has been shown to be useful for Western blotting.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 200 µl
- Storage
- Upon receipt, store frozen at -20° C.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Recombinant human C-reactive protein (20 ng per lane) was resolved by electrophoresis, transferred to nitrocellulose, and probed with rabbit polyclonal antibody against CRP. Proteins were visualized using a donkey anti-rabbit secondary conjugated to HRP and a chemiluminescence detection system.
- Conjugate
- Unconjugated
