326503

antibody from BioLegend
Targeting: CD163 M130, MM130, SCARI1
Provider product page for 326503
Flow cytometry

Antibody data

Product number
326503 - Provider product page
Provider
BioLegend
Product name
Biotin anti-human CD163
Antibody type
Monoclonal
Antigen
human monocytes
Description
CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, Hemoglobin-Haptoglobin Complex Receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kuffer cells, monocytes, subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP) resulting in soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammation diseases.
Reactivity
Human
Host
Mouse
Conjugate
Biotin
Isotype
IgG
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C. Do not freeze.
CD163 protein structure - 326503 shown in red.