10020-1-AP

antibody from Proteintech Group

Targeting: ICAM1 BB2, CD54

Provider product page for 10020-1-AP

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Antibody data

Antibody Data
Antigen structure
References [109]
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Product number: 10020-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#10020-1-AP, RRID:AB_2121773
Product name: Icam-1 antibody
Antibody type: Polyclonal
Description: KD/KO validated Icam-1 antibody (Cat. #10020-1-AP) is a rabbit polyclonal antibody that shows reactivity with mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

ICAM1 protein structure - 10020-1-AP shown in red.

Submitted references ARF6 controls VSMC phenotypic switching upon lipid stimulation to promote inflammatory signaling contributing to the progression of atherosclerosis.

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The Journal of biological chemistry 2026 Mar;302(3):111165

Semaglutide ameliorates aortic endothelial cell dysfunction in sarcopenia through the SIRT1/cGAS-STING signaling axis.

Liu Y, Sun W, Huang Z, Qiao G, Tang L, Huang T, Wang X, Li L, Zhang X, Ye X, Yang P, Wu H
Free radical biology & medicine 2026 Jul;250:352-369

Theacrine protects vascular endothelial cells against oxidative damage after ischemic stroke by inhibiting Rac1 and activating Nrf2 pathway.

Zhang Y, Li Y, Li X, Liao P, Chen W, Feng Y, Zhang X, Chen Y, Nan L, Li H, Yan G
International immunopharmacology 2026 Jan 1;168(Pt 2):115951

Macrophage-Mimicking Biomimetic Microbubbles for Early Ultrasound Molecular Imaging of Acute Rejection in Heart Transplantation.

Wang C, Li G, Chen J, Liu C, Liu Y, Ai X, Yang Y, Leng X, Wang Z, Jiang S
ACS applied materials & interfaces 2026 Feb 4;18(4):6639-6655

Theophylline Inhibits Capillary Degeneration in Early Diabetic Retinopathy.

Lessieur EM, Saadane A, Du Y, Kiser J, Oum A, Bollinger ZR, Lee CA, Tang J, Kern TS
Investigative ophthalmology & visual science 2026 Feb 2;67(2):8

Hydrogen-Enriched Hyaluronic Acid Dressing Ameliorates Diabetic Foot Ulcer via Promoting Mitophagy.

Xu Z, Cui X, Chu H, Wan H, Xie Y, Wang Y, Ni Q, Ding X, Song G
Journal of diabetes 2026 Apr;18(4):e70209

Systematic Analysis of an Immune-Related Gene Signature for Predicting Prognosis and Immune Characteristics in Primary Lower Grade Glioma.

Hou L, Tian L, Li J, Zhang Z, Han X, Zhou H, Xue X
BioMed research international 2025;2025:6180391

Inhibition of ICAM1 diminishes stemness and enhances antitumor immunity in glioblastoma via β-catenin/PD-L1 signaling.

Guo M, Yuan Z, Jin X, Li X, Deng Y, Zhou S, Niu R, Bae J, Park JB, Shi B, Yin J
Nature communications 2025 Sep 30;16(1):8642

The SLCO4A1-Mediated Transmembrane Transport of Lysionotin Attenuates Acute Lung Injury Through Activating the AMPK/Nrf2 Signaling Pathway.

Xiong D, Lin M, Xie W, Zhang X, Huang L, Deng L, Huang X, Liu W, Tang S
Phytotherapy research : PTR 2025 Oct;39(10):4404-4427

Extracellular matrix anchored neutrophils drive pulmonary fibrosis in mice.

Yang L, Sun P, Wang J, Xu M, Zhu B, Yu K, Rong Y, Mao R, Zi S, Liu C, Huang J, Ma J, Chen H, Luo W, Zhang W, Zhang X, Fang S, Chao J
Nature communications 2025 Nov 26;16(1):11655

Hydrogen sulfide improves vascular endothelial function in hypertensive states through SIRT6 anti-inflammatory signaling.

Lu F, Qin X, Lu S, Wan J, Miao Y, Teng X, Jin S, Xiao L, Xue H, Guo Q, Tian D, Wu Y
Acta biochimica et biophysica Sinica 2025 Nov 24;58(4):845-53

Pre-ischaemic empagliflozin treatment attenuates blood-brain barrier disruption via β-catenin mediated protection of cerebral endothelial cells.

Liu G, Qiu Y, You N, Yu M, Chen W, Sun T, Qin Z, Han M, Xue Z, Liang X, Mao B, Ling L, Wu Y, Xing W, Liu Q, Wang D
Cardiovascular research 2025 May 23;121(5):788-802

A nanovaccine for immune activation and prophylactic protection of atherosclerosis in mouse models.

Zhang L, Al-Ammari A, Zhu D, Zhang H, Zhou P, Zhi X, Ding W, Li X, Yu Q, Gai Y, Ma X, Chen C, Zuo C, Zhang J, Zhu W, Sun D
Nature communications 2025 Mar 2;16(1):2111

LncRNA SNHG14 Regulated by ZNF460 Promotes Gastric Cancer Progression and Metastasis by Targeting the miR-206/FNDC3A Axis.

Liu B, Lu T, Zhang G, Dong X, Yu M, Cai H
Journal of cellular and molecular medicine 2025 Jun;29(11):e70652

Interleukin-1 Signaling on Vascular Smooth Muscle Cells Accelerates Atherosclerosis in a Murine Model of Kawasaki Disease.

Chen S, Savas A, Atici A, Lee Y, Lane M, Aubuchon E, Moreira D, Hsu-Wilbraham A, Shimada K, Crother TR, Noval Rivas M, Arditi M
Journal of the American Heart Association 2025 Jun 3;14(11):e040687

Effects of inflammation on hypoxic renal tubular epithelial cell injury under high-glucose conditions and the regulatory role of miR-125b.

Shen X, Liu Y, Zhao J, Cheng Q, Yang G
Scientific reports 2025 Jul 1;15(1):21248

Characterization of microcirculatory endothelial functions in a D-Galactose-induced aging model.

Li Z, He Y, Zhang Q, Li B, Xiu R, Zhang H
Microvascular research 2025 Jan;157:104757

Integrin β2 Plays a Significant Role in Therapeutic Angiogenesis Through Hematopoietic Stem Cell Transplantation.

Saino O, Ogawa Y, Yasui K, Fuchizaki A, Akamatsu R, Irie Y, Tanaka M, Kimura T, Taguchi A
Life (Basel, Switzerland) 2025 Jan 28;15(2)

Steatohepatitis-induced vascular niche alterations promote melanoma metastasis.

Hoffmann J, Schüler J, Dietsch B, Kürschner-Zacharias SW, Sticht C, Trogisch FA, Schreitmüller M, Baljkas T, Schledzewski K, Reinhart M, Wohlfeil SA, Winkler M, Schmid CD, Heineke J, Géraud C, Goerdt S, Reiners-Koch PS, Olsavszky V
Cancer & metabolism 2025 Jan 28;13(1):5

Network pharmacology and animal experiments revealed the protective effects of Guilong prescription on chronic prostatitis and its possible mechanisms.

Peixuan Z, Zeqi SU, Qiongyin F, Cai Z, Ting W
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Feb;45(1):89-99

Role of microvascular pericyte dysfunction in antibody-mediated rejection following kidney transplantation.

Xu J, Pu J, Chen H, Sun L, Fei S, Han Z, Tao J, Ju X, Wang Z, Tan R, Gu M
Renal failure 2025 Dec;47(1):2458749

Distinct populations of lung capillary endothelial cells and their functional significance.

James J, Dekan A, Kacar S, Niihori M, Sano T, McClain N, Varghese M, Bharti D, Lawal OS, Padilla-Rodrigez M, Yi D, Gao H, Tepper RS, Dai Z, Gusev O, Rafikova O, Rafikov R
Communications biology 2025 Dec 26;9(1):140

Esaxerenone inhibits renal macrophage proliferation through MR/TGF-β1 pathway in db/db mice.

Yang F, Liu Z, Li Y, Lv R, Zhao Y, Yang F, Shimosawa T, Tan J, Xu Q, Qiang P
Life sciences 2025 Dec 1;382:124008

Perihematomal Neurovascular Protection: Blocking HSP90 Reduces Blood Infiltration Associated with Inflammatory Effects Following Intracerebral Hemorrhage in Rates.

Hu D, Yan C, Xie H, Wen X, He K, Ding Y, Zhao Y, Meng H, Li K, Yang Z
Translational stroke research 2025 Aug;16(4):1133-1145

SMAD4 Deficiency Promotes Pancreatic Cancer Progression and Confers Susceptibility to TGFβ Inhibition.

Murimwa GZ, Williams NE, Alzhanova D, Mohammadi A, Westcott JM, Beato F, Dai R, Nivelo L, Rossi F, Fleming HK, Tassielli AF, Yazgan Z, Toombs JE, Fleming JB, Singhi AD, Ethun CG, Huang H, Brekken RA
Cancer research 2025 Aug 15;85(16):2987-2996

Neutrophil-like cell membrane-coated metal-organic frameworks for siRNA delivery targeting NOX4 to alleviate oxidative stress in acute ischemic injury.

Wang M, Wang Y, Zhang P, Gu C, Zhao X, Gong X, Yang X, Pan J, Xi Y
Acta biomaterialia 2025 Apr;196:487-505

Cyy-272, an indazole derivative, effectively mitigates obese cardiomyopathy as a JNK inhibitor.

Liu X, Cheng LT, Ye QR, Gao HC, Zhu JW, Zhao K, Liu HM, Wang YJ, Alinejad T, Zhang XH, Chen GZ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117172

A novel PROTAC molecule dBET1 alleviates pathogenesis of experimental autoimmune encephalomyelitis in mice by degrading BRD4.

Song Z, Li J, He Y, Wang X, Tian J, Wu Y
International immunopharmacology 2024 Sep 30;139:112646

Circulating free heme induces cytokine storm and pulmonary hypertension through the MKK3/p38 axis.

Valuparampil Varghese M, James J, Bharti D, Rischard F, Rafikova O, Rafikov R
American journal of physiology. Lung cellular and molecular physiology 2024 Oct 1;327(4):L574-L586

Biomimetic Trypsin-Responsive Structure-Bridged Mesoporous Organosilica Nanomedicine for Precise Treatment of Acute Pancreatitis.

Wang Y, Qian D, Wang X, Zhang X, Li Z, Meng X, Yu L, Yan X, He Z
ACS nano 2024 Jul 23;18(29):19283-19302

Virus-Mimetic Extracellular-Vesicle Vaccine Boosts Systemic and Mucosal Immunity via Immune Recruitment.

Li J, Xing H, Meng F, Liu T, Hong X, Han X, Dong Y, Li M, Wang Z, Zhang S, Cui C, Zheng A
ACS nano 2024 Jul 16;

Modified Guo-Min decoction ameliorates PM2.5-induced lung injury by inhibition of PI3K-AKT and MAPK signaling pathways.

Wang H, Wang G, Meng Y, Liu Y, Yao X, Feng C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155211

Minocycline inhibits microglial activation in the CA1 hippocampal region and prevents long-term cognitive sequel after experimental cerebral malaria.

Moreira ET, Lourenço MP, Cunha-Fernandes T, Silva TI, Siqueira LD, Castro-Faria-Neto HC, Reis PA
Journal of neuroimmunology 2024 Dec 15;397:578480

Therapeutic potential of flavopiridol in diabetic retinopathy: Targeting DDX58.

Zhang X, Hu Q, Peng H, Huang J, Sang W, Guan J, Huang Z, Jiang B, Sun D
International immunopharmacology 2024 Aug 20;137:112504

Exploring the mechanism of Bushen Huoxue prescription in the treatment of early diabetic retinal edema from the perspective of inner blood-retinal barrier injury.

Li J, Guo X, Huang Y, Ren Y, Liang H, Xie X, Zhang M
Journal of ethnopharmacology 2024 Apr 6;323:117658

Second Near-Infrared Macrophage-Biomimetic Nanoprobes for Photoacoustic Imaging of Neuroinflammation.

Pan Y, Chen J, Zhang Y, Ren Y, Wu Z, Xue Q, Zeng S, Fang C, Zhang H, Zhang L, Liu C, Zeng J
Molecular pharmaceutics 2024 Apr 1;21(4):1804-1816

Neutrophil infiltration associated genes on the prognosis and tumor immune microenvironment of lung adenocarcinoma.

Liu R, Zhu G, Sun Y, Li M, Hu Z, Cao P, Li X, Song Z, Chen J
Frontiers in immunology 2023;14:1304529

Repeated Social Defeat Stress Induces an Inflammatory Gut Milieu by Altering the Mucosal Barrier Integrity and Gut Microbiota Homeostasis.

Yadav SK, Ahmad R, Moshfegh CM, Sankarasubramanian J, Joshi V, Elkhatib SK, Chhonker YS, Murry DJ, Talmon GA, Guda C, Case AJ, Singh AB
Biological psychiatry global open science 2023 Oct;3(4):824-836

Exploring the chondroprotective effect of Chaenomeles speciosa on Glucose-6-Phosphate Isomerase model mice using an integrated approach of network pharmacology and experimental validation.

Duan Z, Jin C, Deng Y, Liu J, Gu C, Wang J, Cai X, Li S, Zhou Y
Journal of ethnopharmacology 2023 Oct 5;314:116553

Sirtuin1 Mediates the Protective Effects of Echinacoside against Sepsis-Induced Acute Lung Injury via Regulating the NOX4-Nrf2 Axis.

Xie W, Deng L, Lin M, Huang X, Qian R, Xiong D, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2023 Oct 29;12(11)

Novel soybean polypeptide dglycin alleviates atherosclerosis in apolipoprotein E-deficient mice.

Zhao H, Dan P, Xi J, Chen Z, Zhang P, Wei W, Zhao Y
International journal of biological macromolecules 2023 Nov 1;251:126347

Novel Populations of Lung Capillary Endothelial Cells and Their Functional Significance.

James J, Dekan A, Niihori M, McClain N, Varghese M, Bharti D, Lawal OS, Padilla-Rodrigez M, Yi D, Dai Z, Gusev O, Rafikova O, Rafikov R
Research square 2023 May 3;

Patient-derived melanoma organoid models facilitate the assessment of immunotherapies.

Ou L, Liu S, Wang H, Guo Y, Guan L, Shen L, Luo R, Elder DE, Huang AC, Karakousis G, Miura J, Mitchell T, Schuchter L, Amaravadi R, Flowers A, Mou H, Yi F, Guo W, Ko J, Chen Q, Tian B, Herlyn M, Xu X
EBioMedicine 2023 Jun;92:104614

Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice.

Krzistetzko J, Géraud C, Dormann C, Riedel A, Leibing T
International journal of molecular sciences 2023 Jun 30;24(13)

Activated cGAS/STING signaling elicits endothelial cell senescence in early diabetic retinopathy.

Liu H, Ghosh S, Vaidya T, Bammidi S, Huang C, Shang P, Nair AP, Chowdhury O, Stepicheva NA, Strizhakova A, Hose S, Mitrousis N, Gadde SG, Mb T, Strassburger P, Widmer G, Lad EM, Fort PE, Sahel JA, Zigler JS Jr, Sethu S, Westenskow PD, Proia AD, Sodhi A, Ghosh A, Feenstra D, Sinha D
JCI insight 2023 Jun 22;8(12)

Baicalin inhibited both the Furin/TGFβ1/Smad3/TSP-1 pathway in endothelial cells and the AKT/Ca(2+)/ROS pathway in platelets to ameliorate inflammatory coagulopathy.

Wang P, Wu J, Wang Q, Zhuang S, Zhao J, Yu Y, Zhang W, Zheng Y, Liu X
European journal of pharmacology 2023 Jun 15;949:175674

Diabetes Modulates Iodothyronine Deiodinase 2 Expression in the Mouse Retina: A Role for Thyroid Hormone in the Pathogenesis of Diabetic Retinopathy.

Bapputty R, Sapa H, Masaru M, Gubitosi-Klug RA
Investigative ophthalmology & visual science 2023 Dec 1;64(15):3

SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.

Zheng G, Su Y, Wei L, Yao Y, Wang Y, Luo X, Wang X, Ruan XZ, Li D, Chen Y
Cell death & disease 2023 Apr 6;14(4):249

The Mitigatory Effect of Shen-Qi Compound on the Diabetic Thoracic Aortic Complications through Inhibiting the Inflammatory Microenvironment by miR-223-3p/RBP-J/IRF8 Axis.

Tian Y, Xu G, Gao H, Xie HY, Leng YL, Fu XX, Xie CG
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6686931

Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis.

Chen R, Zeng J, Li C, Xiao H, Li S, Lin Z, Huang K, Shen J, Huang H
Frontiers in pharmacology 2022;13:853383

GNG12 as A Novel Molecular Marker for the Diagnosis and Treatment of Glioma.

Liu R, Liu Z, Zhao Y, Cheng X, Liu B, Wang Y, Wang J, Lian X, Zhu Y, Gao Y
Frontiers in oncology 2022;12:726556

ICAM-1 on the luminal surface of endothelial cells is induced to a greater extent in mouse retina than in other tissues in diabetes.

Lessieur EM, Liu H, Saadane A, Du Y, Kiser J, Kern TS
Diabetologia 2022 Oct;65(10):1734-1744

LipoxinA(4) analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.

Hao H, Xie F, Xu F, Wang Q, Wu Y, Zhang D
International immunopharmacology 2022 Oct;111:109170

Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy.

Liu H, Stepicheva NA, Ghosh S, Shang P, Chowdhury O, Daley RA, Yazdankhah M, Gupta U, Hose SL, Valapala M, Fitting CS, Strizhakova A, Shan Y, Feenstra D, Sahel JA, Jayagopal A, Handa JT, Zigler JS Jr, Fort PE, Sodhi A, Sinha D
Nature communications 2022 Oct 13;13(1):6045

P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy.

Huang L, Chen Y, Liu R, Li B, Fei X, Li X, Liu G, Li Y, Xu B, Fang W
Aging and disease 2022 Oct 1;13(5):1546-1561

Design, synthesis and biological evaluation of marine phidianidine-inspired derivatives against oxidized ldl-induced endothelial injury by activating Nrf2 anti-oxidation pathway.

Xie HX, Wang YH, Zhang JH, Zhang J, Zhong YN, Ge YX, Cheng ZQ, Jiang CS, Meng N
Bioorganic chemistry 2022 Mar;120:105606

Preclinical platforms to study therapeutic efficacy of human γδ T cells.

Ou L, Wang H, Huang H, Zhou Z, Lin Q, Guo Y, Mitchell T, Huang AC, Karakousis G, Schuchter L, Amaravadi R, Guo W, Salvino J, Herlyn M, Xu X
Clinical and translational medicine 2022 Jun;12(6):e814

Is cell regeneration and infiltration a double edged sword for porcine aortic valve deterioration? A large cohort of histopathological analysis.

Li L, Duan X, Wang H, Sun Y, Zhao W, Lu Y, Xu H, You Y, Wang Q
BMC cardiovascular disorders 2022 Jul 28;22(1):336

Neutrophil extracellular traps promote thrombogenicity in cerebral venous sinus thrombosis.

Jin J, Qiao S, Liu J, Li W, Wang F, Gao X, Tian J, Wang N, Zhang J, Dong J, Li H, Wang J, Hu S, Zhou P
Cell & bioscience 2022 Jul 22;12(1):114

Exercise-derived peptide protects against pathological cardiac remodeling.

Yin A, Yuan R, Xiao Q, Zhang W, Xu K, Yang X, Yang W, Xu L, Wang X, Zhuang F, Li Y, Cai Z, Sun Z, Zhou B, He B, Shen L
EBioMedicine 2022 Aug;82:104164

c-Myc participates in high glucose-mediated endothelial inflammation via upregulation of IRAK1 expression in diabetic nephropathy.

Hou W, Lu L, Li X, Sun M, Zhu M, Miao C
Cellular signalling 2022 Apr;92:110263

Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation.

Koch PS, Sandorski K, Heil J, Schmid CD, Kürschner SW, Hoffmann J, Winkler M, Staniczek T, de la Torre C, Sticht C, Schledzewski K, Taketo MM, Trogisch FA, Heineke J, Géraud C, Goerdt S, Olsavszky V
Frontiers in physiology 2021;12:722394

Daphnetin Preconditioning Decreases Cardiac Injury and Susceptibility to Ventricular Arrhythmia following Ischaemia-Reperfusion through the TLR4/MyD88/NF-Κb Signalling Pathway.

Yang F, Jiang X, Cao H, Shuai W, Zhang L, Wang G, Quan D, Jiang X
Pharmacology 2021;106(7-8):369-383

Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.

Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940

Sterol-resistant SCAP Overexpression in Vascular Smooth Muscle Cells Accelerates Atherosclerosis by Increasing Local Vascular Inflammation through Activation of the NLRP3 Inflammasome in Mice.

Li D, Liu M, Li Z, Zheng G, Chen A, Zhao L, Yang P, Wei L, Chen Y, Ruan XZ
Aging and disease 2021 Jun;12(3):747-763

Unveiling the CHO surfaceome: Identification of cell surface proteins reveals cell aggregation-relevant mechanisms.

Klingler F, Mathias S, Schneider H, Buck T, Raab N, Zeh N, Shieh YW, Pfannstiel J, Otte K
Biotechnology and bioengineering 2021 Aug;118(8):3015-3028

Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.

Ma C, Feng K, Yang X, Yang Z, Wang Z, Shang Y, Fan G, Liu L, Yang S, Li X, Han J, Duan Y, Chen Y
British journal of pharmacology 2021 Apr;178(7):1620-1638

Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis.

Yang GS, Zheng B, Qin Y, Zhou J, Yang Z, Zhang XH, Zhao HY, Yang HJ, Wen JK
Theranostics 2020;10(17):7787-7811

Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.

Zhao Y, Tang J, Yang D, Tang C, Chen J
Journal of dairy science 2020 Sep;103(9):8350-8359

Downregulation of G3BP2 reduces atherosclerotic lesions in ApoE(-/-) mice.

Li T, Safitri M, Zhang K, Wang Y, Huang L, Zhu Y, Daniel R, Wu LJ, Qiu J, Wang G
Atherosclerosis 2020 Oct;310:64-74

Endothelial intercellular cell adhesion molecule 1 contributes to cell aggregate formation in CHO cells cultured in serum-free media.

Louie S, Heidersbach A, Blanco N, Haley B, Rose CM, Liu PS, Yim M, Tang D, Lam C, Sandoval WN, Shaw D, Snedecor B, Misaghi S
Biotechnology progress 2020 May;36(3):e2951

Blockade of intercellular adhesion molecule-1 prevents angiotensin II-induced hypertension and vascular dysfunction.

Lang PP, Bai J, Zhang YL, Yang XL, Xia YL, Lin QY, Li HH
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):378-386

Quasi-ultrafine particles promote cell metastasis via HMGB1-mediated cancer cell adhesion.

Gao R, Sang N
Environmental pollution (Barking, Essex : 1987) 2020 Jan;256:113390

Injected laquinimod D-α-tocopheryl polyethylene glycol-1000 succinate polymeric micelles for the treatment of inflammatory bowel disease.

Wang L, Xue P, Tong M, Chen R, Yang W, ZhuGe D, Yuan J, Yao Q, Zhao Y, Xu H
Colloids and surfaces. B, Biointerfaces 2020 Jan 1;185:110575

Inhibition of calcineurin/NFATc4 signaling attenuates ventilator‑induced lung injury.

Li M, Fang XZ, Liu XT, Zheng YF, Xie YB, Ma XD, Xia Y, Shao DH
Molecular medicine reports 2020 Feb;21(2):607-614

Angiocrine Hepatocyte Growth Factor Signaling Controls Physiological Organ and Body Size and Dynamic Hepatocyte Proliferation to Prevent Liver Damage during Regeneration.

Zhang XJ, Olsavszky V, Yin Y, Wang B, Engleitner T, Öllinger R, Schledzewski K, Koch PS, Rad R, Schmid RM, Friess H, Goerdt S, Hüser N, Géraud C, von Figura G, Hartmann D
The American journal of pathology 2020 Feb;190(2):358-371

Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway.

Chen ZQ, Sun XH, Li XJ, Xu ZC, Yang Y, Lin ZY, Xiao HM, Zhang M, Quan SJ, Huang HQ
Acta pharmacologica Sinica 2020 Dec;41(12):1587-1596

DNA damage/cGAS-triggered up-regulation of MALAT1 promotes undesirable inflammatory responses in radiotherapy of cancer.

Yuan C, Wang D, Zhang N, Wang Z, Yang F, He J, Sun R, Yang X, Hu J, Wu M
Biochemical and biophysical research communications 2020 Aug 6;528(4):746-752

ECM1 Prevents Activation of Transforming Growth Factor β, Hepatic Stellate Cells, and Fibrogenesis in Mice.

Fan W, Liu T, Chen W, Hammad S, Longerich T, Hausser I, Fu Y, Li N, He Y, Liu C, Zhang Y, Lian Q, Zhao X, Yan C, Li L, Yi C, Ling Z, Ma L, Zhao X, Xu H, Wang P, Cong M, You H, Liu Z, Wang Y, Chen J, Li D, Hui L, Dooley S, Hou J, Jia J, Sun B
Gastroenterology 2019 Nov;157(5):1352-1367.e13

Low-intensity pulsed ultrasound attenuates cardiac inflammation of CVB3-induced viral myocarditis via regulation of caveolin-1 and MAPK pathways.

Zheng C, Wu SM, Lian H, Lin YZ, Zhuang R, Thapa S, Chen QZ, Chen YF, Lin JF
Journal of cellular and molecular medicine 2019 Mar;23(3):1963-1975

Protective effect of rosiglitazone on chronic renal allograft dysfunction in rats.

Deng J, Xia Y, Zhou Q, Wang X, Xiong C, Shao X, Shao M, Zou H
Transplant immunology 2019 Jun;54:20-28

Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy.

Liu H, Lessieur EM, Saadane A, Lindstrom SI, Taylor PR, Kern TS
Diabetologia 2019 Dec;62(12):2365-2374

TRPC6 modulates adhesion of neutrophils to airway epithelial cells via NF-κB activation and ICAM-1 expression with ozone exposure.

Chen QZ, Zhou YB, Zhou LF, Fu ZD, Wu YS, Chen Y, Li SN, Huang JR, Li JH
Experimental cell research 2019 Apr 15;377(1-2):56-66

Ulcerative colitis-specific delivery of keratinocyte growth factor by neutrophils-simulated liposomes facilitates the morphologic and functional recovery of the damaged colon through alleviating the inflammation.

Zhao YZ, ZhuGe DL, Tong MQ, Lin MT, Zheng YW, Jiang X, Yang WG, Yao Q, Xiang Q, Li XK, Xu HL
Journal of controlled release : official journal of the Controlled Release Society 2019 Apr 10;299:90-106

Effects of Qingshen Granules on the Oxidative Stress-NF/kB Signal Pathway in Unilateral Ureteral Obstruction Rats.

Jin H, Wang Y, Wang D, Zhang L
Evidence-based complementary and alternative medicine : eCAM 2018;2018:4761925

Mechanosensing by β1 integrin induces angiocrine signals for liver growth and survival.

Lorenz L, Axnick J, Buschmann T, Henning C, Urner S, Fang S, Nurmi H, Eichhorst N, Holtmeier R, Bódis K, Hwang JH, Müssig K, Eberhard D, Stypmann J, Kuss O, Roden M, Alitalo K, Häussinger D, Lammert E
Nature 2018 Oct;562(7725):128-132

Control release of mitochondria-targeted antioxidant by injectable self-assembling peptide hydrogel ameliorated persistent mitochondrial dysfunction and inflammation after acute kidney injury.

Zhao M, Zhou Y, Liu S, Li L, Chen Y, Cheng J, Lu Y, Liu J
Drug delivery 2018 Nov;25(1):546-554

Expression and significance of Sirt1 in renal allografts at the early stage of chronic renal allograft dysfunction.

Xia Y, Deng J, Zhou Q, Shao X, Yang X, Sha M, Zou H
Transplant immunology 2018 Jun;48:18-25

Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice.

Leibing T, Géraud C, Augustin I, Boutros M, Augustin HG, Okun JG, Langhans CD, Zierow J, Wohlfeil SA, Olsavszky V, Schledzewski K, Goerdt S, Koch PS
Hepatology (Baltimore, Md.) 2018 Aug;68(2):707-722

Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites.

Feng S, Bowden N, Fragiadaki M, Souilhol C, Hsiao S, Mahmoud M, Allen S, Pirri D, Ayllon BT, Akhtar S, Thompson AAR, Jo H, Weber C, Ridger V, Schober A, Evans PC
Arteriosclerosis, thrombosis, and vascular biology 2017 Nov;37(11):2087-2101

Extracts of Zuo Jin Wan, a traditional Chinese medicine, phenocopies 5-HTR1D antagonist in attenuating Wnt/β-catenin signaling in colorectal cancer cells.

Pan J, Xu Y, Song H, Zhou X, Yao Z, Ji G
BMC complementary and alternative medicine 2017 Nov 28;17(1):506

BTP2, a Store-Operated Calcium Channel Inhibitor, Attenuates Lung Ischemia-Reperfusion Injury in Rats.

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In vitro assessment of deferoxamine on mesenchymal stromal cells from tumor and bone marrow.

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Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.

Gu R, Lei B, Jiang C, Xu G
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Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.

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Puerarin Improves Diabetic Aorta Injury by Inhibiting NADPH Oxidase-Derived Oxidative Stress in STZ-Induced Diabetic Rats.

Li W, Zhao W, Wu Q, Lu Y, Shi J, Chen X
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Human β-defensin-3 alleviates the progression of atherosclerosis accelerated by Porphyromonas gingivalis lipopolysaccharide.

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Neuroprotective effects of Kaempferide-7-O-(4″-O-acetylrhamnosyl)-3-O-rutinoside on cerebral ischemia-reperfusion injury in rats.

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European journal of pharmacology 2016 Oct 5;788:335-342

FTY720 Attenuates Retinal Inflammation and Protects Blood-Retinal Barrier in Diabetic Rats.

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Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes.

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Early treatment with atorvastatin exerts parenchymal and vascular protective effects in experimental cerebral ischaemia.

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Bone marrow cells: Important role on neovascularization of hepatocellular carcinoma.

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Effects of pegylated interferon α2b on metastasis of hepatocellular carcinoma.

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Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation.

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Acta pharmacologica Sinica 2004 Jul;25(7):869-75

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The Icam1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of mouse Icam1. This antibody recognizes mouse, rat antigen. The Icam1 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 10020-1-AP.pdf

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