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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Immunocytochemistry [3]
- Other assay [2]
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- Product number
- PA3-860 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- KCNH2 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Description
- PA3-860 detects HERG in human samples. PA3-860 has been used successfully in Western blot, immunfluorescence, and immunoprecipitation procedures. By Western blot this antibody detects the ~135 kDa and ~155 kDa forms of HERG. The PA3-860 immunogen corresponds to a cDNA fragment of HERG encoding 181 amino acid residues from the C-terminus.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- Conc. Not Determined
- Storage
- -20°C, Avoid Freeze/Thaw Cycles
Submitted references ZC88, a novel 4-amino piperidine analog, inhibits the growth of neuroblastoma cells through blocking hERG potassium channel.
Chronic inhibition of cardiac Kir2.1 and HERG potassium channels by celastrol with dual effects on both ion conductivity and protein trafficking.
HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects.
Wei X, Sun H, Yan H, Zhang C, Zhang S, Liu X, Hua N, Ma X, Zheng J
Cancer biology & therapy 2013 May;14(5):450-7
Cancer biology & therapy 2013 May;14(5):450-7
Chronic inhibition of cardiac Kir2.1 and HERG potassium channels by celastrol with dual effects on both ion conductivity and protein trafficking.
Sun H, Liu X, Xiong Q, Shikano S, Li M
The Journal of biological chemistry 2006 Mar 3;281(9):5877-84
The Journal of biological chemistry 2006 Mar 3;281(9):5877-84
HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects.
Zhou Z, Gong Q, Epstein ML, January CT
The Journal of biological chemistry 1998 Aug 14;273(33):21061-6
The Journal of biological chemistry 1998 Aug 14;273(33):21061-6
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence staining of HERG in HEK 293 cells using Product # PA3-860.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence staining of HERG in HEK 293 cells using Product # PA3-860.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence staining of HERG in HEK 293 cells using Product # PA3-860.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
