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- Antigen structure
- References [59]
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- Other assay [5]
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- Product number
- MA5-13595 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- MMP9 Monoclonal Antibody (GE-213)
- Antibody type
- Monoclonal
- Antigen
- Purifed from natural sources
- Description
- MA5-13595 targets MMP-9 (92kDa Collagenase IV) in IA, IHC (F), and IP applications and shows reactivity with Human samples. The MA5-13595 immunogen is purified human MMP-9.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- GE-213
- Vial size
- 500 μL
- Concentration
- 0.2 mg/mL
- Storage
- 4°C
Submitted references Ganoderma lucidum, a promising agent possessing antioxidant and anti-inflammatory effects for treating calvarial defects with graft application in rats.
CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis.
Potential contribution of phenotypically modulated smooth muscle cells and related inflammation in the development of experimental obstructive pulmonary vasculopathy in rats.
Association of Fascin and matrix metalloproteinase-9 expression with poor prognostic parameters in breast carcinoma of Egyptian women.
Clinical significance of sIL-2R levels in B-cell lymphomas.
High glucose induces reactive oxygen species-dependent matrix metalloproteinase-9 expression and cell migration in brain astrocytes.
Inhibitory effect of midazolam on MMP-9, MMP-1 and MMP-13 expression in PMA-stimulated human chondrocytes via recovery of NF-κB signaling.
PI3-K/Akt/JNK/NF-κB is essential for MMP-9 expression and outgrowth in human limbal epithelial cells on intact amniotic membrane.
Suppression of matrix metalloproteinase-9 expression by andrographolide in human monocytic THP-1 cells via inhibition of NF-κB activation.
The influence of transforming growth factor-α, cyclooxygenase-2, matrix metalloproteinase (MMP)-7, MMP-9 and CXCR4 proteins involved in epithelial-mesenchymal transition on overall survival of patients with gastric cancer.
Identification of distinct gene expression profiles between esophageal squamous cell carcinoma and adjacent normal epithelial tissues.
Identification of distinct gene expression profiles between esophageal squamous cell carcinoma and adjacent normal epithelial tissues.
Expression of LGR8 and related biomarkers in hepatocellular carcinoma: correlation with clinicopathological parameters.
Expression of LGR8 and related biomarkers in hepatocellular carcinoma: correlation with clinicopathological parameters.
Association between testicular Aryl hydrocarbon Receptor levels and idiopathic male infertility: a case-control study in Iran.
Matrix metalloproteinase-9 potentiates early brain injury after subarachnoid hemorrhage.
Expression of metalloproteases and their inhibitors by tumor and stromal cells in ductal carcinoma in situ of the breast and their relationship with microinvasive events.
Nuclear-targeted inhibition of NF-kappaB on MMP-9 production by N-2-(4-bromophenyl) ethyl caffeamide in human monocytic cells.
Study of matrix metalloproteinases and their inhibitors in prostate cancer.
Expression of metalloproteases and their inhibitors in different histological types of breast cancer.
Immunohistochemical study of matrix metalloproteinases and their inhibitors in pure and mixed invasive and in situ ductal carcinomas of the breast.
Expression of metalloproteases and their inhibitors in primary tumors and in local recurrences after mastectomy for breast cancer.
Immunohistochemical expression of epidermal growth factor receptor, E-cadherin, and matrix metalloproteinase-9 in ovarian epithelial cancer and relation to patient deaths.
MMP19 is upregulated during melanoma progression and increases invasion of melanoma cells.
Immunohistochemical expression of matrix metalloproteinases in photodamaged skin by photodynamic therapy.
Progression and observational frequency of atheromatous plaques in autopsied coronary arteries.
VAMP3, syntaxin-13 and SNAP23 are involved in secretion of matrix metalloproteinases, degradation of the extracellular matrix and cell invasion.
Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways.
The expression of six biomarkers in the four most common ovarian cancers: correlation with clinicopathological parameters.
Inhibitory effect of CD147/HAb18 monoclonal antibody on cartilage erosion and synovitis in the SCID mouse model for rheumatoid arthritis.
Comparative analysis and clinical value of the expression of metalloproteases and their inhibitors by intratumor stromal fibroblasts and those at the invasive front of breast carcinomas.
Syndecan-2 functions as a docking receptor for pro-matrix metalloproteinase-7 in human colon cancer cells.
Atherosclerotic progression attenuates the expression of Nogo-B in autopsied coronary artery: pathology and virtual histology intravascular ultrasound analysis.
GSK-3-specific inhibitor-supplemented hESC medium prevents the epithelial-mesenchymal transition process and the up-regulation of matrix metalloproteinases in hESCs cultured in feeder-free conditions.
Expression of matrix metalloproteinases 2 and 9 in odontogenic myxoma in vivo and in vitro.
Differential expression of stromal MMP-1, MMP-9 and TIMP-1 in basal cell carcinomas of immunosuppressed patients and controls.
Collagenase-2 (matrix metalloproteinase-8) plays a protective role in tongue cancer.
Expression of E-cadherin, beta-catenin, cathepsin D, gelatinases and their inhibitors in invasive ductal breast carcinomas.
Overexpression of matrix metalloproteinases and their inhibitors in mononuclear inflammatory cells in breast cancer correlates with metastasis-relapse.
Matrix metalloproteinase-9 activity is associated with poor prognosis in T3-T4 node-negative colorectal cancer.
Matrix metalloproteinases and their inhibitors in the chamber angle of normal eyes and patients with primary open-angle glaucoma and exfoliation glaucoma.
Usefulness of MMP-9/TIMP-1 in predicting tumor recurrence in patients undergoing curative surgical resection for gastric carcinoma.
Study of matrix metalloproteinases and their inhibitors in breast cancer.
Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer.
Recombination of CXCR4, VEGF, and MMP-9 predicting lymph node metastasis in human breast cancer.
Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1.
Significance of matrix metalloproteinase 9 and CD34 expressions in esophageal carcinoma: correlation with DNA content.
Significance of matrix metalloproteinase 9 and CD34 expressions in esophageal carcinoma: correlation with DNA content.
Role of matrix metalloproteinase-9 in ex vivo expansion of human limbal epithelial cells cultured on human amniotic membrane.
Expression of matrix metalloproteinase-9 in pleural effusions of tuberculosis and lung cancer.
Intracellular and cell surface localization of a complex between alphaMbeta2 integrin and promatrix metalloproteinase-9 progelatinase in neutrophils.
Diminished matrix metalloproteinase 9 secretion in human immunodeficiency virus-infected mononuclear phagocytes: modulation of innate immunity and implications for neurological disease.
Derivation and characterization of a Wilms' tumour cell line, WiT 49.
Imbalance between expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in invasiveness and metastasis of human gastric carcinoma.
Imbalance between expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in invasiveness and metastasis of human gastric carcinoma.
Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin.
Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin.
Extracellular matrix and matrix metalloproteinase changes in human corneas after complicated laser-assisted in situ keratomileusis (LASIK).
Extracellular matrix and matrix metalloproteinase changes in human corneas after complicated laser-assisted in situ keratomileusis (LASIK).
Laçin N, İzol SB, İpek F, Tuncer MC
Acta cirurgica brasileira 2019;34(9):e201900904
Acta cirurgica brasileira 2019;34(9):e201900904
CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis.
Chen XW, Yu TJ, Zhang J, Li Y, Chen HL, Yang GF, Yu W, Liu YZ, Liu XX, Duan CF, Tang HL, Qiu M, Wang CL, Zheng H, Yue J, Guo AM, Yang J
Oncogene 2017 Aug 31;36(35):5045-5057
Oncogene 2017 Aug 31;36(35):5045-5057
Potential contribution of phenotypically modulated smooth muscle cells and related inflammation in the development of experimental obstructive pulmonary vasculopathy in rats.
Otsuki S, Sawada H, Yodoya N, Shinohara T, Kato T, Ohashi H, Zhang E, Imanaka-Yoshida K, Shimpo H, Maruyama K, Komada Y, Mitani Y
PloS one 2015;10(2):e0118655
PloS one 2015;10(2):e0118655
Association of Fascin and matrix metalloproteinase-9 expression with poor prognostic parameters in breast carcinoma of Egyptian women.
Youssef NS, Hakim SA
Diagnostic pathology 2014 Jul 4;9:136
Diagnostic pathology 2014 Jul 4;9:136
Clinical significance of sIL-2R levels in B-cell lymphomas.
Yoshida N, Oda M, Kuroda Y, Katayama Y, Okikawa Y, Masunari T, Fujiwara M, Nishisaka T, Sasaki N, Sadahira Y, Mihara K, Asaoku H, Matsui H, Seto M, Kimura A, Arihiro K, Sakai A
PloS one 2013;8(11):e78730
PloS one 2013;8(11):e78730
High glucose induces reactive oxygen species-dependent matrix metalloproteinase-9 expression and cell migration in brain astrocytes.
Hsieh HL, Lin CC, Hsiao LD, Yang CM
Molecular neurobiology 2013 Dec;48(3):601-14
Molecular neurobiology 2013 Dec;48(3):601-14
Inhibitory effect of midazolam on MMP-9, MMP-1 and MMP-13 expression in PMA-stimulated human chondrocytes via recovery of NF-κB signaling.
Wang JJ, Huan SK, Hsieh KH, Chou HC, Hsiao G, Jayakumar T, Sheu JR
Archives of medical science : AMS 2013 Apr 20;9(2):332-9
Archives of medical science : AMS 2013 Apr 20;9(2):332-9
PI3-K/Akt/JNK/NF-κB is essential for MMP-9 expression and outgrowth in human limbal epithelial cells on intact amniotic membrane.
Cheng CY, Hsieh HL, Hsiao LD, Yang CM
Stem cell research 2012 Jul;9(1):9-23
Stem cell research 2012 Jul;9(1):9-23
Suppression of matrix metalloproteinase-9 expression by andrographolide in human monocytic THP-1 cells via inhibition of NF-κB activation.
Lee WR, Chung CL, Hsiao CJ, Chou YC, Hsueh PJ, Yang PC, Jan JS, Cheng YW, Hsiao G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2012 Feb 15;19(3-4):270-7
Phytomedicine : international journal of phytotherapy and phytopharmacology 2012 Feb 15;19(3-4):270-7
The influence of transforming growth factor-α, cyclooxygenase-2, matrix metalloproteinase (MMP)-7, MMP-9 and CXCR4 proteins involved in epithelial-mesenchymal transition on overall survival of patients with gastric cancer.
Fanelli MF, Chinen LT, Begnami MD, Costa WL Jr, Fregnami JH, Soares FA, Montagnini AL
Histopathology 2012 Aug;61(2):153-61
Histopathology 2012 Aug;61(2):153-61
Identification of distinct gene expression profiles between esophageal squamous cell carcinoma and adjacent normal epithelial tissues.
Tao Y, Chai D, Ma L, Zhang T, Feng Z, Cheng Z, Wu S, Qin Y, Lai M
The Tohoku journal of experimental medicine 2012 Apr;226(4):301-11
The Tohoku journal of experimental medicine 2012 Apr;226(4):301-11
Identification of distinct gene expression profiles between esophageal squamous cell carcinoma and adjacent normal epithelial tissues.
Tao Y, Chai D, Ma L, Zhang T, Feng Z, Cheng Z, Wu S, Qin Y, Lai M
The Tohoku journal of experimental medicine 2012 Apr;226(4):301-11
The Tohoku journal of experimental medicine 2012 Apr;226(4):301-11
Expression of LGR8 and related biomarkers in hepatocellular carcinoma: correlation with clinicopathological parameters.
Lin CK, Jin JS, Yu CP, Tsai WC
The Chinese journal of physiology 2011 Jun 30;54(3):161-8
The Chinese journal of physiology 2011 Jun 30;54(3):161-8
Expression of LGR8 and related biomarkers in hepatocellular carcinoma: correlation with clinicopathological parameters.
Lin CK, Jin JS, Yu CP, Tsai WC
The Chinese journal of physiology 2011 Jun 30;54(3):161-8
The Chinese journal of physiology 2011 Jun 30;54(3):161-8
Association between testicular Aryl hydrocarbon Receptor levels and idiopathic male infertility: a case-control study in Iran.
Bidgoli SA, Karimi M, Asami Z, Baher H, Djamali Zavarhei M
The Science of the total environment 2011 Aug 15;409(18):3267-73
The Science of the total environment 2011 Aug 15;409(18):3267-73
Matrix metalloproteinase-9 potentiates early brain injury after subarachnoid hemorrhage.
Guo Z, Sun X, He Z, Jiang Y, Zhang X, Zhang JH
Neurological research 2010 Sep;32(7):715-20
Neurological research 2010 Sep;32(7):715-20
Expression of metalloproteases and their inhibitors by tumor and stromal cells in ductal carcinoma in situ of the breast and their relationship with microinvasive events.
González LO, González-Reyes S, Junquera S, Marín L, González L, Del Casar JM, González JM, Vizoso F
Journal of cancer research and clinical oncology 2010 Sep;136(9):1313-21
Journal of cancer research and clinical oncology 2010 Sep;136(9):1313-21
Nuclear-targeted inhibition of NF-kappaB on MMP-9 production by N-2-(4-bromophenyl) ethyl caffeamide in human monocytic cells.
Chou YC, Sheu JR, Chung CL, Chen CY, Lin FL, Hsu MJ, Kuo YH, Hsiao G
Chemico-biological interactions 2010 Mar 30;184(3):403-12
Chemico-biological interactions 2010 Mar 30;184(3):403-12
Study of matrix metalloproteinases and their inhibitors in prostate cancer.
Escaff S, Fernández JM, González LO, Suárez A, González-Reyes S, González JM, Vizoso FJ
British journal of cancer 2010 Mar 2;102(5):922-9
British journal of cancer 2010 Mar 2;102(5):922-9
Expression of metalloproteases and their inhibitors in different histological types of breast cancer.
Del Casar JM, González-Reyes S, González LO, González JM, Junquera S, Bongera M, García MF, Andicoechea A, Serra C, Vizoso FJ
Journal of cancer research and clinical oncology 2010 Jun;136(6):811-9
Journal of cancer research and clinical oncology 2010 Jun;136(6):811-9
Immunohistochemical study of matrix metalloproteinases and their inhibitors in pure and mixed invasive and in situ ductal carcinomas of the breast.
Gonzalez LO, Junquera S, del Casar JM, González L, Marín L, González-Reyes S, Andicoechea A, González-Fernández R, González JM, Pérez-Fernández R, Vizoso FJ
Human pathology 2010 Jul;41(7):980-9
Human pathology 2010 Jul;41(7):980-9
Expression of metalloproteases and their inhibitors in primary tumors and in local recurrences after mastectomy for breast cancer.
del Casar JM, Carreño G, González LO, Junquera S, González-Reyes S, González JM, Bongera M, Merino AM, Vizoso FJ
Journal of cancer research and clinical oncology 2010 Jul;136(7):1049-58
Journal of cancer research and clinical oncology 2010 Jul;136(7):1049-58
Immunohistochemical expression of epidermal growth factor receptor, E-cadherin, and matrix metalloproteinase-9 in ovarian epithelial cancer and relation to patient deaths.
Alshenawy HA
Annals of diagnostic pathology 2010 Dec;14(6):387-95
Annals of diagnostic pathology 2010 Dec;14(6):387-95
MMP19 is upregulated during melanoma progression and increases invasion of melanoma cells.
Müller M, Beck IM, Gadesmann J, Karschuk N, Paschen A, Proksch E, Djonov V, Reiss K, Sedlacek R
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010 Apr;23(4):511-21
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010 Apr;23(4):511-21
Immunohistochemical expression of matrix metalloproteinases in photodamaged skin by photodynamic therapy.
Almeida Issa MC, Piñeiro-Maceira J, Farias RE, Pureza M, Raggio Luiz R, Manela-Azulay M
The British journal of dermatology 2009 Sep;161(3):647-53
The British journal of dermatology 2009 Sep;161(3):647-53
Progression and observational frequency of atheromatous plaques in autopsied coronary arteries.
Lee WS, Kim SW, Ryu WS
Korean circulation journal 2009 Oct;39(10):399-407
Korean circulation journal 2009 Oct;39(10):399-407
VAMP3, syntaxin-13 and SNAP23 are involved in secretion of matrix metalloproteinases, degradation of the extracellular matrix and cell invasion.
Kean MJ, Williams KC, Skalski M, Myers D, Burtnik A, Foster D, Coppolino MG
Journal of cell science 2009 Nov 15;122(Pt 22):4089-98
Journal of cell science 2009 Nov 15;122(Pt 22):4089-98
Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways.
Lolmede K, Campana L, Vezzoli M, Bosurgi L, Tonlorenzi R, Clementi E, Bianchi ME, Cossu G, Manfredi AA, Brunelli S, Rovere-Querini P
Journal of leukocyte biology 2009 May;85(5):779-87
Journal of leukocyte biology 2009 May;85(5):779-87
The expression of six biomarkers in the four most common ovarian cancers: correlation with clinicopathological parameters.
Lin CK, Chao TK, Yu CP, Yu MH, Jin JS
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2009 Mar;117(3):162-75
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2009 Mar;117(3):162-75
Inhibitory effect of CD147/HAb18 monoclonal antibody on cartilage erosion and synovitis in the SCID mouse model for rheumatoid arthritis.
Jia J, Wang C, Shi Z, Zhao J, Jia Y, Zhao-Hui Z, Li X, Chen Z, Zhu P
Rheumatology (Oxford, England) 2009 Jul;48(7):721-6
Rheumatology (Oxford, England) 2009 Jul;48(7):721-6
Comparative analysis and clinical value of the expression of metalloproteases and their inhibitors by intratumor stromal fibroblasts and those at the invasive front of breast carcinomas.
Del Casar JM, González LO, Alvarez E, Junquera S, Marín L, González L, Bongera M, Vázquez J, Vizoso FJ
Breast cancer research and treatment 2009 Jul;116(1):39-52
Breast cancer research and treatment 2009 Jul;116(1):39-52
Syndecan-2 functions as a docking receptor for pro-matrix metalloproteinase-7 in human colon cancer cells.
Ryu HY, Lee J, Yang S, Park H, Choi S, Jung KC, Lee ST, Seong JK, Han IO, Oh ES
The Journal of biological chemistry 2009 Dec 18;284(51):35692-701
The Journal of biological chemistry 2009 Dec 18;284(51):35692-701
Atherosclerotic progression attenuates the expression of Nogo-B in autopsied coronary artery: pathology and virtual histology intravascular ultrasound analysis.
Lee WS, Kim SW, Hong SA, Lee TJ, Park ES, Kim HJ, Lee KJ, Kim TH, Kim CJ, Ryu WS
Journal of Korean medical science 2009 Aug;24(4):596-604
Journal of Korean medical science 2009 Aug;24(4):596-604
GSK-3-specific inhibitor-supplemented hESC medium prevents the epithelial-mesenchymal transition process and the up-regulation of matrix metalloproteinases in hESCs cultured in feeder-free conditions.
Ullmann U, Gilles C, De Rycke M, Van de Velde H, Sermon K, Liebaers I
Molecular human reproduction 2008 Mar;14(3):169-79
Molecular human reproduction 2008 Mar;14(3):169-79
Expression of matrix metalloproteinases 2 and 9 in odontogenic myxoma in vivo and in vitro.
Miyagi SP, Hiraki KR, Martins MD, Marques MM
Journal of oral science 2008 Jun;50(2):187-92
Journal of oral science 2008 Jun;50(2):187-92
Differential expression of stromal MMP-1, MMP-9 and TIMP-1 in basal cell carcinomas of immunosuppressed patients and controls.
Boyd S, Tolvanen K, Virolainen S, Kuivanen T, Kyllönen L, Saarialho-Kere U
Virchows Archiv : an international journal of pathology 2008 Jan;452(1):83-90
Virchows Archiv : an international journal of pathology 2008 Jan;452(1):83-90
Collagenase-2 (matrix metalloproteinase-8) plays a protective role in tongue cancer.
Korpi JT, Kervinen V, Mäklin H, Väänänen A, Lahtinen M, Läärä E, Ristimäki A, Thomas G, Ylipalosaari M, Aström P, Lopez-Otin C, Sorsa T, Kantola S, Pirilä E, Salo T
British journal of cancer 2008 Feb 26;98(4):766-75
British journal of cancer 2008 Feb 26;98(4):766-75
Expression of E-cadherin, beta-catenin, cathepsin D, gelatinases and their inhibitors in invasive ductal breast carcinomas.
Zhang YG, DU J, Tian XX, Zhong YF, Fang WG
Chinese medical journal 2007 Sep 20;120(18):1597-605
Chinese medical journal 2007 Sep 20;120(18):1597-605
Overexpression of matrix metalloproteinases and their inhibitors in mononuclear inflammatory cells in breast cancer correlates with metastasis-relapse.
González LO, Pidal I, Junquera S, Corte MD, Vázquez J, Rodríguez JC, Lamelas ML, Merino AM, García-Muñiz JL, Vizoso FJ
British journal of cancer 2007 Oct 8;97(7):957-63
British journal of cancer 2007 Oct 8;97(7):957-63
Matrix metalloproteinase-9 activity is associated with poor prognosis in T3-T4 node-negative colorectal cancer.
Cho YB, Lee WY, Song SY, Shin HJ, Yun SH, Chun HK
Human pathology 2007 Nov;38(11):1603-10
Human pathology 2007 Nov;38(11):1603-10
Matrix metalloproteinases and their inhibitors in the chamber angle of normal eyes and patients with primary open-angle glaucoma and exfoliation glaucoma.
Rönkkö S, Rekonen P, Kaarniranta K, Puustjärvi T, Teräsvirta M, Uusitalo H
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2007 May;245(5):697-704
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2007 May;245(5):697-704
Usefulness of MMP-9/TIMP-1 in predicting tumor recurrence in patients undergoing curative surgical resection for gastric carcinoma.
Seo YS, Park JJ, Kim JH, Kim JY, Yeon JE, Kim JS, Byun KS, Bak YT
Digestive diseases and sciences 2007 Mar;52(3):753-9
Digestive diseases and sciences 2007 Mar;52(3):753-9
Study of matrix metalloproteinases and their inhibitors in breast cancer.
Vizoso FJ, González LO, Corte MD, Rodríguez JC, Vázquez J, Lamelas ML, Junquera S, Merino AM, García-Muñiz JL
British journal of cancer 2007 Mar 26;96(6):903-11
British journal of cancer 2007 Mar 26;96(6):903-11
Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer.
Kubben FJ, Sier CF, Hawinkels LJ, Tschesche H, van Duijn W, Zuidwijk K, van der Reijden JJ, Hanemaaijer R, Griffioen G, Lamers CB, Verspaget HW
European journal of cancer (Oxford, England : 1990) 2007 Aug;43(12):1869-76
European journal of cancer (Oxford, England : 1990) 2007 Aug;43(12):1869-76
Recombination of CXCR4, VEGF, and MMP-9 predicting lymph node metastasis in human breast cancer.
Hao L, Zhang C, Qiu Y, Wang L, Luo Y, Jin M, Zhang Y, Guo TB, Matsushima K, Zhang Y
Cancer letters 2007 Aug 8;253(1):34-42
Cancer letters 2007 Aug 8;253(1):34-42
Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1.
Ries C, Pitsch T, Mentele R, Zahler S, Egea V, Nagase H, Jochum M
The Biochemical journal 2007 Aug 1;405(3):547-58
The Biochemical journal 2007 Aug 1;405(3):547-58
Significance of matrix metalloproteinase 9 and CD34 expressions in esophageal carcinoma: correlation with DNA content.
El-Kenawy Ael-M, Lotfy M, El-Kott A, El-Shahat M
Journal of clinical gastroenterology 2005 Oct;39(9):791-4
Journal of clinical gastroenterology 2005 Oct;39(9):791-4
Significance of matrix metalloproteinase 9 and CD34 expressions in esophageal carcinoma: correlation with DNA content.
El-Kenawy Ael-M, Lotfy M, El-Kott A, El-Shahat M
Journal of clinical gastroenterology 2005 Oct;39(9):791-4
Journal of clinical gastroenterology 2005 Oct;39(9):791-4
Role of matrix metalloproteinase-9 in ex vivo expansion of human limbal epithelial cells cultured on human amniotic membrane.
Sun CC, Cheng CY, Chien CS, Pang JH, Ku WC, Chen PY, Yang CM
Investigative ophthalmology & visual science 2005 Mar;46(3):808-15
Investigative ophthalmology & visual science 2005 Mar;46(3):808-15
Expression of matrix metalloproteinase-9 in pleural effusions of tuberculosis and lung cancer.
Park KJ, Hwang SC, Sheen SS, Oh YJ, Han JH, Lee KB
Respiration; international review of thoracic diseases 2005 Mar-Apr;72(2):166-75
Respiration; international review of thoracic diseases 2005 Mar-Apr;72(2):166-75
Intracellular and cell surface localization of a complex between alphaMbeta2 integrin and promatrix metalloproteinase-9 progelatinase in neutrophils.
Stefanidakis M, Ruohtula T, Borregaard N, Gahmberg CG, Koivunen E
Journal of immunology (Baltimore, Md. : 1950) 2004 Jun 1;172(11):7060-8
Journal of immunology (Baltimore, Md. : 1950) 2004 Jun 1;172(11):7060-8
Diminished matrix metalloproteinase 9 secretion in human immunodeficiency virus-infected mononuclear phagocytes: modulation of innate immunity and implications for neurological disease.
Ciborowski P, Enose Y, Mack A, Fladseth M, Gendelman HE
Journal of neuroimmunology 2004 Dec;157(1-2):11-6
Journal of neuroimmunology 2004 Dec;157(1-2):11-6
Derivation and characterization of a Wilms' tumour cell line, WiT 49.
Alami J, Williams BR, Yeger H
International journal of cancer 2003 Nov 10;107(3):365-74
International journal of cancer 2003 Nov 10;107(3):365-74
Imbalance between expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in invasiveness and metastasis of human gastric carcinoma.
Zhang S, Li L, Lin JY, Lin H
World journal of gastroenterology 2003 May;9(5):899-904
World journal of gastroenterology 2003 May;9(5):899-904
Imbalance between expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in invasiveness and metastasis of human gastric carcinoma.
Zhang S, Li L, Lin JY, Lin H
World journal of gastroenterology 2003 May;9(5):899-904
World journal of gastroenterology 2003 May;9(5):899-904
Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin.
Ratzinger G, Stoitzner P, Ebner S, Lutz MB, Layton GT, Rainer C, Senior RM, Shipley JM, Fritsch P, Schuler G, Romani N
Journal of immunology (Baltimore, Md. : 1950) 2002 May 1;168(9):4361-71
Journal of immunology (Baltimore, Md. : 1950) 2002 May 1;168(9):4361-71
Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin.
Ratzinger G, Stoitzner P, Ebner S, Lutz MB, Layton GT, Rainer C, Senior RM, Shipley JM, Fritsch P, Schuler G, Romani N
Journal of immunology (Baltimore, Md. : 1950) 2002 May 1;168(9):4361-71
Journal of immunology (Baltimore, Md. : 1950) 2002 May 1;168(9):4361-71
Extracellular matrix and matrix metalloproteinase changes in human corneas after complicated laser-assisted in situ keratomileusis (LASIK).
Maguen E, Zorapapel NC, Zieske JD, Ninomiya Y, Sado Y, Kenney MC, Ljubimov AV
Cornea 2002 Jan;21(1):95-100
Cornea 2002 Jan;21(1):95-100
Extracellular matrix and matrix metalloproteinase changes in human corneas after complicated laser-assisted in situ keratomileusis (LASIK).
Maguen E, Zorapapel NC, Zieske JD, Ninomiya Y, Sado Y, Kenney MC, Ljubimov AV
Cornea 2002 Jan;21(1):95-100
Cornea 2002 Jan;21(1):95-100
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Immunoprecipitation of MMP-9 (92kDa Collagenase IV) using MMP-9 (92kDa Collagenase IV) Monoclonal Antibody (Product # MA5-13595) on Native Human HT1080-TPA (Medium) Cells.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
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- Figure 1 Left: examples of tissue with immunostaining for the more significant proteins in patients with tumours belong to poor prognostic group (cluster 2 group: A , B and C ) and better prognostic group (cluster 1 group: D , E and F ; magnification x 400). ( A ) Immunohistochemical staining of matrix metalloproteinase (MMP)-11 in inflammatory mononuclear cells, tumour cells and fibroblastic cells. ( B ) Immunohistochemical staining of MMP-9 in inflammatory mononuclear cells, tumour cells and fibroblastic cell negatives. ( C ) Immunohistochemical staining of tissular inhibitors of metalloproteinase (TIMP)-1 in inflammatory mononuclear cells and in fibroblastic cells, tumour cell negatives. ( D ) No immunohistochemical staining of MMP-9 in inflammatory mononuclear cells, tumour cells and fibroblastic cells. ( E ) Immunohistochemical staining of MMP-11 in tumour cells, inflammatory mononuclear cells and fibroblastic cell negatives. ( F ) Immunohistochemical staining of TIMP-1 in fibroblastic cells, inflammatory mononuclear cells and tumour cell negatives. In all cases, inflammatory mononuclear cells are indicated with small arrows, and fibroblastic cells with large arrows.
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- Figure 1 Fascin and MMP-9 expressions in normal breast tissue and invasive ductal carcinomas. a : Moderate fascin expression in the myoepithelial cells and luminal cells of few normal acini (IHC x 400). b : Positive cytoplasmic fascin expression in malignant cells (IHC x 400). c : Negative MMP-9 expression in normal breast tissue (IHC x 400). d : Positive cytoplasmic MMP-9 expression of malignant cells with weak expression of stromal cells (IHC x 400).
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- Figure 2 Fascin and MMP-9 expression in invasive ductal carcinomas with adjacent in situ component. (a) : Positive cytoplasmic fascin expression in the myoepithelial cells of the in situ component (IHC x 200). (b) : Positive cytoplasmic fascin expression in the in situ carcinoma lesions as well as the adjacent invasive carcinoma (IHC x 200). (c) : Positive cytoplasmic MMP-9 expression in the in situ carcinoma lesions (IHC x 200). (d) : Positive cytoplasmic MMP-9 expression in invasive carcinoma and negative expression in the in situ carcinoma lesions (IHC x 200).
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- Figure 5 Invasive ductal breast carcinomas. a : Enhanced fascin expression at the leading edge of the tumor (IHC x 100). b : The same field with higher magnification power showing positive cytoplasmic fascin expression of malignant cells and endothelial cells (IHC x 200). c : Enhanced MMP-9 expression at the tumor-host border (IHC x 100). d : The same field with higher magnification power showing positive cytoplasmic MMP-9 expression of malignant cells (IHC x 200).
