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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Flow cytometry [3]
- Other assay [3]
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- Product number
- MA1-19594 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD105 Monoclonal Antibody (MEM-226), FITC
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- This antibody reacts with an extracellular epitope of CD105 (Endoglin), a 90 kDa type I homodimerizing membrane glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow; it is also present on syncytiotrophoblast on placenta throughout pregnancy.
- Reactivity
- Human, Rat
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Antibody clone number
- MEM-226
- Vial size
- 100 Tests
- Concentration
- 0.03 mg/mL
- Storage
- 4°C, store in dark, DO NOT FREEZE!
Submitted references Transplanted allogeneic cardiac progenitor cells secrete GDF-15 and stimulate an active immune remodeling process in the ischemic myocardium.
Bcl-xL mutant promotes cartilage differentiation of BMSCs by upregulating TGF-β/BMP expression levels.
VAP-PLGA microspheres (VAP-PLGA) promote adipose-derived stem cells (ADSCs)-induced wound healing in chronic skin ulcers in mice via PI3K/Akt/HIF-1α pathway.
Sodium Selenite Improves The Therapeutic Effect Of BMSCs Via Promoting The Proliferation And Differentiation, Thereby Promoting The Hematopoietic Factors.
Mishra R, Saha P, Datla SR, Mellacheruvu P, Gunasekaran M, Guru SA, Fu X, Chen L, Bolli R, Sharma S, Kaushal S
Journal of translational medicine 2022 Jul 21;20(1):323
Journal of translational medicine 2022 Jul 21;20(1):323
Bcl-xL mutant promotes cartilage differentiation of BMSCs by upregulating TGF-β/BMP expression levels.
Xiao K, Yang L, Xie W, Gao X, Huang R, Xie M
Experimental and therapeutic medicine 2021 Jul;22(1):736
Experimental and therapeutic medicine 2021 Jul;22(1):736
VAP-PLGA microspheres (VAP-PLGA) promote adipose-derived stem cells (ADSCs)-induced wound healing in chronic skin ulcers in mice via PI3K/Akt/HIF-1α pathway.
Jiang W, Zhang J, Zhang X, Fan C, Huang J
Bioengineered 2021 Dec;12(2):10264-10284
Bioengineered 2021 Dec;12(2):10264-10284
Sodium Selenite Improves The Therapeutic Effect Of BMSCs Via Promoting The Proliferation And Differentiation, Thereby Promoting The Hematopoietic Factors.
Yan D, Tang B, Yan L, Zhang L, Miao M, Chen X, Sui G, Zhang Q, Liu D, Wang H
OncoTargets and therapy 2019;12:9685-9696
OncoTargets and therapy 2019;12:9685-9696
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometry analysis of CD105 using a monoclonal antibody (Product # MA1-19594).
- Conjugate
- Green dye
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Separation of HUVEC cells stained using anti-human CD105 (MEM-226) FITC Monoclonal antibody (Product # MA1-19594), 20 µL reagent per million cells in 100 µL of cell suspension (red-filled) from unstained HUVEC cells (black-dashed) in flow cytometry analysis (surface staining) of HUVEC cells.
- Conjugate
- Green dye
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Separation of HUVEC cells stained using anti-human CD105 (MEM-226) FITC Monoclonal antibody (Product # MA1-19594), 20 µL reagent per million cells in 100 µL of cell suspension (red-filled) from unstained HUVEC cells (black-dashed) in flow cytometry analysis (surface staining) of HUVEC cells.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 1 Culture and identification of bone marrow mesenchymal stem cells. (A) Light microscopy of BMSCs (scale bar=100 um for the left image and 200 um for the right image). (B) Percentage of CD34-, CD45-, CD73-, CD90- and CD105-positive BMSCs were detected by flow cytometry. BMSC, bone marrow mesenchymal stem cell.
- Conjugate
- Green dye
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 1. Morphology and immune phenotype of adipose-derived stem cells (ADSCs) were identified by morphological observation and flow cytometry. (a) Morphology of the primary (P1) and third passage (P3) of ADSCs. Images were acquired at 200x magnification. (b) Immune phenotype of ADSCs. The average data from three independent experiments were shown as mean +- standard deviation
- Conjugate
- Green dye
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 1 Identification of BMSCs in mice. Morphological observations at different magnifications (40x, 100x, and 200x) showed that the bone marrow stem cells (BMSCs) isolated from mice were homogeneously elongated ( A ). Various cell surface markers of BMSCs were detected on the cells, including CD90, CD73, CD105, CD44, and CD45 ( B ). The values are from triplicate determinations. A P value less than 0.05 was considered to be statistically significant. ***Indicates a P value less than 0.001.
- Conjugate
- Green dye
