Explore
Validate
LearnPA1-41303
antibody from Invitrogen Antibodies
Targeting: CCR5
CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Western blot
Other assayAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Other assay [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PA1-41303 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CCR5 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Suggested positive control: MCF-7 whole cell lysates.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 μg
- Concentration
- 0.5 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Effects of CCL5 on the biological behavior of breast cancer and the mechanisms of its interaction with tumor‑associated macrophages.
Cigarette smoke promotes HIV infection of primary bronchial epithelium and additively suppresses CFTR function.
An G, Wu F, Huang S, Feng L, Bai J, Gu S, Zhao X
Oncology reports 2019 Dec;42(6):2499-2511
Oncology reports 2019 Dec;42(6):2499-2511
Cigarette smoke promotes HIV infection of primary bronchial epithelium and additively suppresses CFTR function.
Chinnapaiyan S, Dutta R, Bala J, Parira T, Agudelo M, Nair M, Unwalla HJ
Scientific reports 2018 May 22;8(1):7984
Scientific reports 2018 May 22;8(1):7984
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 2 CS increases expression of HIV receptors CD4 and CCR5 in NHBE ALI cultures. NHBE ALI cultures were exposed to CS and total protein was extracted. Cells were lysed with RIPA buffer containing protease inhibitor cocktail and protein expression was quantified by Western blot analysis and normalized using beta-actin. CS significantly enhances expression of CD4 (panel a) and CCR5 protein expression (panel b) when compared to air-exposed controls. CS does not increase CXCR4 protein expression (panel c). Western blot images ( a - c ) are representative of NHBE ALI cultures from three independent lungs. Relative density of the detected protein band was measured by using the ImageJ software and the values obtained were averaged. n = 3 lungs (unless stated otherwise). *Significant (p < 0.05).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 2. Expression of CCL5 and its receptor in different breast cancer cell lines and the secretion of CCL5. (A) The mRNA expression levels of CCL5, CCR1, CCR3 and CCR5 in different breast cancer cells; MCF-7 cells served as a control, while GAPDH expression was an internal reference. **P
