ALX-804-225-C100

antibody from Enzo Life Sciences

Targeting: BAX BCL2L4

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

ALX-804-225-C100

Provider

Enzo Life Sciences

Proper citation

Enzo Life Sciences Cat#ALX-804-225-C100, RRID:AB_2050801

Product name

Bax (human) monoclonal antibody (2D2)

Antibody type

Monoclonal

Antigen

Synthetic peptide

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

2D2

Vial size

100 μg

Storage

+4°C

Handling

Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20¡C.

References

Submitted references

Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis.

Yethon JA, Epand RF, Leber B, Epand RM, Andrews DW
The Journal of biological chemistry 2003 Dec 5;278(49):48935-41

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Direct addition of BimL to mitochondria does not lead to cytochrome c release.

Terradillos O, Montessuit S, Huang DC, Martinou JC
FEBS letters 2002 Jul 3;522(1-3):29-34

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Nonionic detergents induce dimerization among members of the Bcl-2 family.

Hsu YT, Youle RJ
The Journal of biological chemistry 1997 May 23;272(21):13829-34

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Movement of Bax from the cytosol to mitochondria during apoptosis.

Wolter KG, Hsu YT, Smith CL, Nechushtan A, Xi XG, Youle RJ
The Journal of cell biology 1997 Dec 1;139(5):1281-92

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Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis.

Hsu YT, Wolter KG, Youle RJ
Proceedings of the National Academy of Sciences of the United States of America 1997 Apr 15;94(8):3668-72